Catherijne Knibbe (Prof. Dr.) is Professor of Individualized Drug Treatment.

More information about Catherijne Knibbe

Professional background & training
Professor Knibbe is a staff hospital pharmacist-clinical pharmacologist in the St. Antonius Hospital in Nieuwegein since 2001, staff member at the Division of Systems Pharmacology and Pharmacy of the Leiden Academic Centre for Drugs Research since 2003 and has been involved in many research projects in the Erasmus MC/Sophia Children’s hospital Rotterdam since 2003 through guest appointments. She was appointed Professor of Individualized Drug Treatment at the Leiden University in 2010.

She studied pharmacy at Utrecht University where she received MSc and Pharm D degrees in 1994 and 1996 respectively. After graduation she qualified as a hospital pharmacist in 2001, as a clinical pharmacologist in 2002 at the Department of Clinical Pharmacy of the St. Antonius Hospital in Nieuwegein and received her PhD at Leiden University in 2002.　　 

Research
In July 2006 she received a Veni grant from the Dutch Organization of Scientific Research NWO allowing her to combine clinical responsibilities as a hospital pharmacist-clinical pharmacologist in Anesthesiology and Intensive Care with the start of a research group developing rational dosing schemes for paediatric indications using population PK-PD modeling within a multidisciplinary and multicentre platform (Division of Pharmacology, LACDR, Leiden, Erasmus MC/Sophia Children's Hospital Rotterdam and UMCU/Wilhelmina Children's Hospital, Utrecht).

More recently, she has extended her research line to develop individualized dosing schemes for morbidly obese children and adults (BMI>40 kg/m²), for which a large number of clinical trials have been initiated, mainly funded by ZonMw.　

In 2013 she received the highly prestigious Vidi grant from the Dutch Organization of Scientific Research NWO for her research line ‘From Descriptive to Predictive Pharmacology in Children using Semi-Physiological population modelling’.　　

She has supervised 23 PhD students, is currently supervising 10 PhD students and 2 Post Docs, and is co-author of over 250 international peer-reviewed publications and contributions to books. She is a frequently invited speaker on national and international conferences.

Awards
Beside the Best PhD Thesis Award 2002 by the Dutch Society of Clinical Pharmacology and Biopharmacy, she was awarded in 2009 the ‘Huizenga penning’ by the Dutch Society of Hospital Pharmacy, which is an award presented to young Dutch hospital-pharmacists for scientific work of outstanding quality. Many of her (former) PhD students have received awards for their work. Dr. Knibbe became a Fellow (FCP) of the American College of Clinical Pharmacology (ACCP) in 2019.

Other activities
In the St. Antonius hospital, Dr. Knibbe is member of the Management Board of the Department of Clinical Pharmacy of the St. Antonius hospital, supervisor of the Clinical Pharmacology training program, co-supervisor of the Hospital Pharmacy training program, and consultant for the department of Intensive Care and Anesthesiology. She is a member of the Board of Regents of the American College of Clinical Pharmacology, member of the Central Committee of Research Involving Human Subjects (the 'CCMO') in The Hague, member of the certification committee of the Dutch Society of Clinical Pharmacology & Biopharmacy, member of the national expert group on dosing guidelines for obese and bariatric surgery patients of the KNMP, and has been chair of the Concilium Hospital Pharmacy of the Dutch Society of Hospital Pharmacy and member of the national Committee of State ‘Doek’ involving medical-ethical aspects of (non-therapeutic) research in children.

Publications