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ZonMW awards funding for LACDR research project to develop novel biomarkers for bacterial infections

As part of the ZonMW Antibiotics resistance funding program, the LACDR cluster Systems Pharmacology was awarded €455.255 for a research project to develop novel clinical biomarkers for bacterial infections.

 The aim of these novel biomarkers was to enable individualized antibiotics treatment while simultaneously reducing the risk of antibiotic resistance development.

The aim of these novel biomarkers is to enable individualized antibiotics treatment while simultaneously reducing the risk of antibiotic resistance development.

The project will be led by LACDR researchers Coen van Hasselt, Thomas Hankemeier and Catherijne Knibbe. The work will be done in close collaboration with clinicians at the St Antoniusziekenhuis (E. van de Garde, W.J. Bos) en het UMC Utrecht (D.W de lange), where several clinical studies have been conducted that form the basis of this project.

The ZonMW evaluation commission determined the research proposal to be of high relevance. The strong combination of state-of-the-art art metabolomics and computational systems pharmacology approached together with relevant clinical data was considered a strong characteristic of this research project.