Sander van Kasteren
Assistant professor
- Naam
- Dr. S.I. van Kasteren
- Telefoon
- +31 71 527 4725
- s.i.van.kasteren@chem.leidenuniv.nl
Meer informatie is beschikbaar op de Engelse profielpagina.
Promovendi
Nieuws
Assistant professor
- Wiskunde en Natuurwetenschappen
- Leiden Institute of Chemistry
- LIC/Bio-organic Synthesis
- Poolman J.M., Maity C., Boekhoven J., Mee L. van der, Sage V.A.A. le, Groenewold G.J.M., Kasteren S.I. van, Versluis F., Esch J.H. van & Eelkema R. (2016), A toolbox for controlling the properties and functionalisation of hydrazone-based supramolecular hydrogels, JOURNAL OF MATERIALS CHEMISTRY B 4(5): 852-858.
- Elsland D.M. van, Bos E., Boer W. de, Overkleeft H.S., Koster A.J. & Kasteren S.I. van (2016), Detection of bioorthogonal groups by correlative light and electron microscopy allows imaging of degraded bacteria in phagocytes, CHEMICAL SCIENCE 7(1): 752-758.
- Pawlak J.B., Hos B.J., Graaff M.J. van de, Megantari O.A, Meeuwenoord N., Overkleeft H.S., Filippov D.V., Ossendorp F. & Kasteren S.I. van. (2016), The Optimization of Bioorthogonal Epitope Ligation within MHC-I Complexes, ACS CHEMICAL BIOLOGY .
- Versluis F., Elsland D.M. van, Mytnyk S., Perrier D.L., Trausel F., Poolman J.M., Maity C., Sage V.A. le, Kasteren S.I. van, Esch J.H. & Eelkema R. (2016), Negatively Charged Lipid Membranes Catalyze Supramolecular Hydrogel Formation., Journal of the American Chemical Society 138(28): 8670-8673.
- Jagessar S.A., Holtman I.R., Hofman S., Morandi E., Heijmans N., Laman J.D., Gran B., Faber B.W., Kasteren S.I. van, Eggen B.J. & 't Hart B.A. (2016), Lymphocryptovirus Infection of Nonhuman Primate B Cells Converts Destructive into Productive Processing of the Pathogenic CD8 T Cell Epitope in Myelin Oligodendrocyte Glycoprotein., Journal of immunology (Baltimore, Md. : 1950) 197(4): 1074-1088.
- Elsland D.M. van & Kasteren S.I. van (2016), Imaging Bioorthogonal Groups in Their Ultrastructural Context with Electron Microscopy., Angewandte Chemie (International ed. in English) 55(33): 9472-9473.
- Pawlak J.B., Hos B., Megantari O.A., Ossendorp F.A. & Kasteren S.I. van (2016), Bias-free imaging of antigen degradation using bioorthogonal antigens, Journal of Immunology 196.
- Pawlak J.B., Gential G.P.P., Ruckwardt T.J., Bremmers J.S., Meeuwenoord N.J., Ossendorp F.A., Overkleeft H.S., Filippov D.V. & Kasteren S.I. (2015), Bioorthogonal Deprotection on the Dendritic Cell Surface for Chemical Control of Antigen Cross-Presentation, Angewandte Chemie International Edition 54(19): 5628-5631.
- Watts C. & Kasteren S.I. van (2015), Inhibitors against endosomal/lysosomal enzymes ( octrooi nr. 9,050,374), (USPTO). [octrooi]
- Elsland D.M. van, Bos E., Overkleeft H.S., Koster A.J. & Kasteren S.I. van (2015), The potential of bioorthogonal chemistry for correlative light and electron microscopy: a call to arms, Journal of Chemical Biology 8(4): 1-5.
- Burkhard C., Verheije M. H. Verheije, Wicht O., Kasteren S.I. van, Kuppeveld F.J. van, Haagmans B.L., Pelkmans L., Rottier P.J.M., Bosch B.J. & Haan C.A.M. de (2014), Coronavirus Cell Entry Occurs through the Endo-/Lysosomal Pathway in a Proteolysis-Dependent Manner, PLOS PATHOGENS 10(11).
- Willems Lianne I., Overkleeft Herman S. & van Kasteren Sander I. (2014), Current Developments in Activity-Based Protein Profiling, BIOCONJUGATE CHEMISTRY 25(7): 1181-1191.
- Engelsma Sander B., Willems Lianne I., van Paaschen Claudia E., van Kasteren Sander I., van der Marel Gijsbert A., Overkleeft Herman S. & Filippov Dmitri V. (2014), Acylazetine as a Dienophile in Bioorthogonal Inverse Electron-Demand Diels-Alder Ligation, 16(10): 2744-2747.
- van Kasteren Sander I., Overkleeft Hermen, Ovaa Huib & Neefjes Jacques (2014), Chemical biology of antigen presentation by MHC molecules, Current Opinion in Immunology 26: 21-31.
- Kasteren S.I. van & Overkleeft H.S. (2014), Endo-lysosomal proteases in antigen presentation , Current opinion in chemical biology 23(0): 8 - 15.
- Ekkebus R., Kasteren S.I. van, Kulathu Y., Scholten A., Berlin I., Geurink P.P., Jong A. de, Goerdayal S., Neefjes J., Heck A.J.R., Komander D. & Ovaa H. (2013), On Terminal Alkynes That Can React with Active-Site Cysteine Nucleophiles in Proteases, Journal of the American Chemical Society 135(8): 2867-2870.
- Ovaa H., Ekkebus R., Kasteren S.I. van, Jong de A. & Geurink P.P. (2013), Cysteine protease capturing agents ( octrooi nr. 14/412,990), (USPTO). [octrooi]
- Kasteren S. van (2012), Synthesis of post-translationally modified proteins, Biochemical Society Transactions 40: 929-944.
- Kujala P., Raymond C.R., Romeijn M., Godsave S.F., Kasteren S.I. van, Wille H., Prusiner S.B., Mabbott N.A. & Peters P.J. (2011), Prion Uptake in the Gut: Identification of the First Uptake and Replication Sites, PLOS PATHOGENS 7(12): e1002449.
- Kasteren S.I. van, Berlin I., Colbert J.D., Keane D., Ovaa H. & Watts C. (2011), A Multifunctional Protease Inhibitor To Regulate Endolysosomal Function, ACS CHEMICAL BIOLOGY 6(11): 1198-1204.
- Sibson N.R., Anthony D.C., Kasteren S. van, Dickens A., Perez-Balderas F., McAteer M.A., Choudhury R.P. & Davis B.G. (2011), Molecular MRI Approaches to the Detection of CNS Inflammation. In: Magnetic Resonance Neuroimaging. nr. 711: Humana Press. 379-396.
- Garnier P., Wang X.T., Robinson M.A., Kasteren S. van, Perkins A.C., Frier M., Fairbanks A.J. & Davis B.G. (2010), Lectin-directed enzyme activated prodrug therapy (LEAPT): Synthesis and evaluation of rhamnose-capped prodrugs, JOURNAL OF DRUG TARGETING 18(10): 794-802.
- Serres S., Anthony D.C., Jiang Y., Broom K.A., Campbell S.J., Tyler D.J., Kasteren S.I. van, Davis B.G. & Sibson N.R. (2009), Systemic Inflammatory Response Reactivates Immune-Mediated Lesions in Rat Brain, Journal of Neuroscience 29(15): 4820-4828.
- Kasteren S.I. van, Campbell S.J., Serres S., Anthony D.C., Sibson N.R. & Davis B.G. (2009), Glyconanoparticles allow pre-symptomatic in vivo imaging of brain disease, Proceedings of the National Academy of Sciences of the United States of America 106(1): 18-23.
- Kasteren S.I. van, Garnier P. & Davis B.G. (2009), Chemical Methods for Mimicking Post-Translational Modifications. In: Protein Engineering. nr. 22: Springer Berlin Heidelberg. 97-125.
- Gamblin D.P., Kasteren S. van, Bernardes G.J.L., Chalker J.M., Oldham N.J., Fairbanks A.J. & Davis B.G. (2008), Chemical site-selective prenylation of proteins, Molecular Biosystems 4(6): 558-561.
- Gamblin D.P., Kasteren S.I. van, Chalker J.M. & Davis B.G. (2008), Chemical approaches to mapping the function of post-translational modifications, FEBS Journal 275(9): 1949-1959.
- Kasteren S.I. van, Kramer H.B., Gamblin D.P. & Davis B.G. (2007), Site-selective glycosylation of proteins: creating synthetic glycoproteins, NATURE PROTOCOLS 2(12): 3185-3194.
- Kasteren S.I. van, Kramer H.B., Jensen H.H., Campbell S.J., Kirkpatrick J., Oldham N.J., Anthony D.C. & Davis B.G. (2007), Expanding the diversity of chemical protein modification allows post-translational mimicry, 446(7139): 1105-1109.
- Davis B., Kasteren S. van, Anthony D. & Sibson N. (2007), Imaging agent comprising iron containing colloidal particle conjugated to oligosaccharides ( octrooi nr. 2,007,020,450), (WO). [octrooi]
- Gamblin D.P., Garnier P., Kasteren S. van, Oldham N.J., Fairbanks A.J. & Davis B.G. (2004), Glyco-SeS: Selenenylsulfide-mediated protein glycoconjugation - A new strategy in post-translational modification, Angewandte Chemie International Edition 43(7): 828-833.
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