Mark Overhand
Universitair hoofddocent
- Naam
- Dr.ing. M. Overhand
- Telefoon
- +31 71 527 1762
- m.overhand@chem.leidenuniv.nl
- ORCID iD
- 0000-0002-7086-4889
Promovendi
Universitair hoofddocent
- Wiskunde en Natuurwetenschappen
- Leiden Institute of Chemistry
- LIC/Opleidingen
- Miao Q., Dekkers M.W.A., Sai Sankar Gupta K.B., Overhand M., Dasgupta R. & Ubbink M. (2023), Rigidified and Hydrophilic DOTA-like Lanthanoid Ligands: Design, Synthesis, and Dynamic Properties, Inorganic Chemistry 62(9): 3776–3787.
- Miao Q., Nitsche C., Orton H., Overhand M., Otting G. & Ubbink M. (2022), Paramagnetic chemical probes for studying biological macromolecules, Chemical Reviews 122(10): 9571-9642.
- Miao Q., Zurlo E., Bruin D. de, Wondergem J.A.J., Skinner S.P., Timmer M., Cramer A.J., Heinrich D.M., Overhand M. & Huber M.I. (2021), Corrigendum: a two-armed probe for in-cell DEER measurements on proteins (vol 26, pg 17128, 2020), Chemistry: a European Journal 27(23): 6994-6994.
- Miao Q., Zurlo E., Bruin D. de, Wondergem A.J., Timmer M., Blok A.J., Heinrich D.M., Overhand M., Huber M.I. & Ubbink M. (2020), A two‐armed probe for in‐cell DEER measurements on proteins, Chemistry: a European Journal 26(71): 17128-17133.
- Miao Q., Liu W.-M., Kock T., Blok A.J., Timmer M., Overhand M. & Ubbink M. (2019), A double-armed, hydrophilic transition metal complex as paramagnetic NMR probe, Angewandte Chemie (International Edition) 58(37): 13093-13100.
- Nabuurs R.J.A., Kapoerchan V.V., Metaxas A., Hafith S., Backer M. de, Welling M.M., Jiskoot W., Nieuwendijk A.M.C.H. van den, Windhorst A.D., Overkleeft H.S., Buchem M.A. van, Overhand M. & Weerd L. van der (2016), Bis-pyridylethenyl benzene as novel backbone for amyloid-beta binding compounds, Bioorganic & Medicinal Chemistry 24(23): 6139-6148.
- Schilder J., Liu W.M., Kumar P., Overhand M., Huber M.I. & Ubbink M. (2016), Protein docking using an ensemble of spin labels optimized by intra-molecular paramagnetic relaxation enhancement, Physical Chemistry Chemical Physics 18(8): 5729-5742.
- Swierstra J., Kapoerchan V., Knijnenburg A., Belkum A. van & Overhand M. (2016), Structure, toxicity and antibiotic activity of gramicidin S and derivatives, European Journal of Clinical Microbiology and Infectious Diseases 35(5): 763-769.
- Schilder J., Liu W.M., Kumar P., Overhand M., Huber M.I. & Ubbink M. (2016), Protein docking using an ensemble of spin labels optimized by intra-molecular paramagnetic relaxation enhancement, Physical Chemistry Chemical Physics 18(8): 5729-5742.
- Liu W.M., Overhand M. & Ubbink M. (2014), The application of paramagnetic lanthanoid ions in NMR spectroscopy on proteins, Coordination Chemistry Reviews 273: 2-12.
- Liu W.M., Skinner S.P., Timmer M., Blok A., Hass M.A.S., Filippov D.V., Overhand M. & Ubbink M. (2014), A Two-Armed Lanthanoid-Chelating Paramagnetic NMR Probe Linked to Proteins via Thioether Linkages, Chemistry: a European Journal 20(21): 6256-6258.
- Nabuurs Rob J.A., Kapoerchan Varsha V., Metaxas Athanasios, De Jongh Sanne, De Backer Maaike, Welling Mick M., Jiskoot Wim, Windhorst Albert D., Overkleeft Hermen S., Van Buchem Mark A., Overhand Mark & Van der Weerd Louise (2014), Polyfluorinated bis-styrylbenzenes as amyloid-beta plaque binding ligands, 22(8): 2469-2481.
- Cavalli S., Overhand M. & Kros A. (2014), Assembly into beta-Sheet Structures upon Peptide-Liposome Conjugation through Copper(I)-Catalyzed 3+2 Azide-Alkyne Cycloaddition, ChemPlusChem 79(4): 564-568.
- Guisado-Barrios Gregorio, Munoz Bianca K., Kamer Paul C.J., Lastdrager Bas, Van der Marel Gijs, Overhand Mark, Vega-Vazquez Marino & Martin-Pastor Manuel (2013), Cyclic decapeptide gramicidin S derivatives containing phosphines: novel ligands for asymmetric catalysis, Dalton Transactions 42(6): 1973-1978.
- Otero Jose M., van der Knaap Matthijs, Llamas-Saiz Antonio L., Van Raaij Mark J., Amorin Manuel, Granja Juan R., Filippov Dmitri V., Van der Marel Gijsbert A., Overkleeft Herman S. & Overhand Mark (2013), Design, Synthesis, and Structural Analysis of Turn Modified cyclo-(alpha beta(3)alpha beta(2)alpha)(2) Peptide Derivatives toward Crystalline Hexagon-Shaped Cationic Nanochannel Assemblies, Crystal Growth & Design 13(10): 4355-4367.
- Risseeuw Martijn, Overhand Mark, Fleet George W.J. & Simone Michela I. (2013), A compendium of cyclic sugar amino acids and their carbocyclic and heterocyclic nitrogen analogues, Amino Acids 45(4): 613-689.
- Van der Knaap M., Otero J.M., Llamas-Saiz A.L., Van Raaij M.J., Lageveen L.I., Busscher H.J., Grotenbreg G.M., Van der Marel G.A., Overkleeft H.S. & Overhand M. (2012), Design, synthesis and structural analysis of mixed alpha/beta-peptides that adopt stable cyclic hairpin-like conformations, Tetrahedron 68(10): .
- Van der Knaap M., Basalan F., Van de Mei H.C., Busscher H.J., Van der Marel G.A., Overkleeft H.S. & Overhand M. (2012), Synthesis and Biological Evaluation of Gramicidin S-Inspired Cyclic Mixed a/ss-Peptides, Chemistry and Biodiversity 9(11): .
- Liu W.M., Keizers P.H.J., Hass M.A.S., Blok A.J., Timmer M., Sarris A.J.C., Overhand M. & Ubbink M. (2012), A pH-Sensitive, Colorful, Lanthanide-Chelating Paramagnetic NMR Probe, Journal of the American Chemical Society 134(41): 17306-17313.
- Li J., Girard G., Florea B.I., Geurink P.P., Li N., Marel G.A. van der, Overhand M., Overkleeft H.S. & Wezel G.P. van (2012), Identification and isolation of lantibiotics from culture: a bioorthogonal chemistry approach, Organic and Biomolecular Chemistry 10(43): 8677-8683.
- Knijnenburg A.D., Spalburg E., De Neeling A.J., Mars-Groenendijk R.H., Noort D., Grotenbreg G.M., Van der Marel G.A., Overkleeft H.S. & Overhand M. (2012), Ring-Extended Gramicidin S Analogs Containing cis d-Sugar Amino Acid Turn Mimetics with Varying Ring Size, Helvetica Chimica Acta 95(12): .
- Kapoerchan V.V., Knijnenburg A.D., Keizer P., Spalburg E., De Neeling A.J., Mars-Groenendijk R.H., Noort D., Otero J.M., Llamas-Saiz A.L., Van Raaij M.J., Van der Marel G.A., Overkleeft H.S. & Overhand M. (2012), 'Inverted' analogs of the antibiotic gramicidin S with an improved biological profile, Bioorganic & Medicinal Chemistry 20(20): .
- Knijnenburg A.D., Tuin A.W., Spalburg E., De Neeling A.J., Mars-Groenendijk R.H., Noort D., Otero J.M., Llamas-Saiz A.L., Van Raaij M.J., Van der Marel G.A., Overkleeft H.S. & Overhand M. (2011), Exploring the Conformational and Biological Versatility of beta-Turn-Modified Gramicidin S by Using Sugar Amino Acid Homologues that Vary in Ring Size, Chemistry: a European Journal 17(14): .
- Knijnenburg A.D., Kapoerchan V.V., Grotenbreg G.M., Spalburg E., De Neeling A.J., Mars-Groenendijk R.H., Noort D., Otero J.M., Llamas-Saiz A.L., Van Raaij M.J., Ravensbergen B., Nibbering P.H., Van der Marel G.A., Overkleeft H.S. & Overhand M. (2011), Synthesis and evaluation of strand and turn modified ring-extended gramicidin S derivatives, 19(11): .
- Dasgupta S., Hu X.Y., Keizers P.H.J., Liu W.M., Luchinat C., Nagulapalli M., Overhand M., Parigi G., Sgheri L. & Ubbink M. (2011), Narrowing the conformational space sampled by two-domain proteins with paramagnetic probes in both domains, Journal of Biomolecular NMR 51(3): 253-263.
- Van der Knaap M., Lageveen L.T., Busscher H.J., Mars-Groenendijk R.H., Noort D., Otero J.M., Llamas-Saiz A.L., Van Raaij M.J., Van der Marel G.A., Overkleeft H.S. & Overhand M. (2011), Evaluation of Readily Accessible Azoles as Mimics of the Aromatic Ring of D-Phenylalanine in the Turn Region of Gramicidin S, ChemMedChem 6(5): .
- Risseeuw M.D., Florea B.I., Van der Marel G.A., Overkleeft H.S. & Overhand M. (2010), Sugar amino acid based peptide epoxyketones as potential proteasome inhibitors, Bioorg Chem 38(5): 202-209.
- Kapoerchan V.V., Knijnenburg A.D., Niamat M., Spalburg E., De Neeling A.J., Nibbering P.H., Mars-Groenendijk R.H., Noort D., Otero J.M., Llamas-Saiz A.L., Van Raaij M.J., Van der Marel G.A., Overkleeft H.S. & Overhand M. (2010), An adamantyl amino acid containing gramicidin S analogue with broad spectrum antibacterial activity and reduced hemolytic activity, Chemistry: a European Journal 16(40): .
- Kapoerchan V.V., Spalburg E., De Neeling A.J., Mars-Groenendijk R.H., Noort D., Otero J.M., Ferraces-Casais P., Llamas-Saiz A.L., Van Raaij M.J., Van Doorn J., Van der Marel G.A., Overkleeft H.S. & Overhand M. (2010), Gramicidin S derivatives containing cis- and trans-morpholine amino acids (MAAs) as turn mimetics, Chemistry: a European Journal 16(14): .
- Keizers P.H.J., Mersinli B., Reinle W., Donauer J., Hiruma Y., Hannemann F., Overhand M., Bernhardt R. & Ubbink M. (2010), A Solution Model of the Complex Formed by Adrenodoxin and Adrenodoxin Reductase Determined by Paramagnetic NMR Spectroscopy, Biochemistry 49(32): 6846-6855.
- Semrau S., Monster M.W.L., Knaap M. van der, Florea B.I., Schmidt T. & Overhand M. (2010), Membrane lysis by gramicidin S visualized in red blood cells and giant vesicles, Biochimica et Biophysica Acta - Biomembranes 1798(11): .
- Kapoerchan V.V., Wiesner M., Hillaert U., Drijfhout J.W., Overhand M., Alard P., Van der Marel G.A., Overkleeft H.S. & Koning F. (2010), Design, synthesis and evaluation of high-affinity binders for the celiac disease associated HLA-DQ2 molecule, Molecular Immunology 47(5): .
- Knijnenburg A.D., Kapoerchan V.V., Spalburg E., De Neeling A.J., Mars-Groenendijk R.H., Noort D., Van der Marel G.A., Overkleeft H.S. & Overhand M. (2010), Tuning hydrophobicity of highly cationic tetradecameric Gramicidin S analogues using adamantane amino acids, Bioorganic & Medicinal Chemistry : .
- Tuin A.W., Grotenbreg G.M., Spalburg E., De Neeling A.J., Mars-Groenendijk R.H., Van der Marel G.A., Noort D., Overkleeft H.S. & Overhand M. (2009), Structural and biological evaluation of some loloatin C analogues, 17(17): 6233-6240.
- Tuin A.W., Palachanis D.K., Buizert A., Grotenbreg G.M., Spalburg E., De Neeling A.J., Mars-Groenendijk R.H., Noort D., Van der Marel G.A., Overkleeft H.S. & Overhand M. (2009), Synthesis and Biological Evaluation of Novel Gramicidin S Analogues, European Journal of Organic Chemistry (25): 4231-4241.
- Risseeuw M.D.P., Van der Marel G.A., Overkleeft H.S. & Overhand M. (2009), Pyranocyclopropanyl sugar amino acids, a new class of constrained (di)peptide isosteres, Tetrahedron Asymmetry 20(6-8): 945-951.
- Risseeuw M.D.P., Van den Berg R., Donker-Koopman W.E., Van der Marel G.A., Aerts J., Overhand M. & Overkleeft H.S. (2009), Synthesis and evaluation of D-gluco-pyranocyclopropyl amines as potential glucosidase inhibitors, Bioorganic and Medicinal Chemistry Letters 19(23): 6600-6603.
- Burck S., Van Assema S.G.A., Lastdrager B., Slootweg J., Ehlers A., Otero J.M., Dacunha-Marinho B., Llamas-Saiz A.L., Overhand M., Van Raaij M.J. & Lammertsma K. (2009), Bisphosphine-Functionalized Cyclic Decapeptides Based on the Natural Product Gramicidin S: A Potential Scaffold for Transition-Metal Coordination, Chemistry: a European Journal 15(33): 8134-8145.
- Knijnenburg A.D., Spalburg E., De Neelin A.J., Mars-Groenendijk R.H., Noort D., Grotenbreg G.M., Van der Marel G.A., Overkleeft H.S. & Overhand M. (2009), Ring-Extended Derivatives of Gramicidin S with Furanoid Sugar Amino Acids in the Turn Region Have Enhanced Antimicrobial Activity, ChemMedChem 4(12): 1976-1979.
- Van der Knaap M., Engels E., Busscher H.J., Otero J.M., Llamas-Saiz A.L., Van Raaij M.J., Mars-Groenendijk R.H., Noort D., Van der Marel G.A., Overkleeft H.S. & Overhand M. (2009), Synthesis and biological evaluation of asymmetric gramicidin S analogues containing modified D-phenylalanine residues, 17(17): 6318-6328.
- Kapoerchan V., Wiesner M., Overhand M., Marel G.A. van der, Koning F. & Overkleeft H.S. (2008), Design of azidoproline containing gluten peptides to suppress CD4+ T-cell responses associated with Celiac disease, Bioorganic & Medicinal Chemistry 16: 2053.
- Kapoerchan V., Wiesner M., Overhand M., Marel G.A. van der, Koning F. & Overkleeft H.S. (2008), Conjugation of nucleosides and oligonucleotides by [3+2] cycloaddition, Bioorganic & Medicinal Chemistry 16(4): 2053-2062.
- Keizers P.H., Saragliadis A., Hiruma Y., Overhand M. & Ubbink M. (2008), Design, Synthesis, and Evaluation of a Lanthanide Chelating Protein Probe: CLaNP-5 Yields Predictable Paramagnetic Effects Independent of Environment, Journal of the American Chemical Society 130: 14802-14812.
- Kapoerchan V., Wiesner M., Overhand M., Marel G.A. van der, Koning F. & Overkleeft H.S. (2007), Design of azidoproline containing gluten peptides to suppress, Bioorganic & Medicinal Chemistry : .
- Popescu D.C., Cavalli S., Tellers E., Vos M.R.J., Pichon B.P., Overhand M., Kros A. & Sommerdijk N.A.J.M. (2007), Lipopeptide monolayers as template for the mineralization of CaCO3. In: , Biomineralization: From Paleontology to Materials Sciences.
- Vlasie M.D., Comuzzi C., Nieuwendijk A.M.C.H. van den, Prudencio M., Overhand M. & Ubbink M. (2007), Long-range-distance NMR effects in a protein labeled with a lanthanide-DOTA chelate, Chemistry: a European Journal 13(6): 1715-1723.
- Cavalli S., Handgraaf J.W., Tellers E., Popescu A.M., Overhand M., Kjaer K., Vaiser V., Sommerdijk N.A.J.M., Rapaport H. & Kros A. (2006), Two-dimensional ordered beta-sheet lipopeptide monolayers, Journal of the American Chemical Society 128(42): 13959-13966.
- Cavalli S., Popescu D., Tellers E., Overhand M., Rapaport H., Sommerdijk N.A.J.M. & Kros A. (2006), Beta-sheet lipopeptide monolayers as an ordered template for the mineralization of Calcite: Importance of adaptability, Abstracts of Papers of the American Chemical Society 231(343): .
- Cavalli S., Tipton A.R., Overhand M. & Kros A. (2006), The chemical modification of liposome surfaces via a copper-mediated [3+2] azide-alkyne cycloaddition monitored by a colorimetric assay, Chemical Communications 30: 3193-3195.
- Koning M.C. de, Petersen L., Weterings J.J., Overhand M., Marel G.A. van der & Filippov D.V. (2006), Synthesis of thiol-modified peptide nucleic acids designed for post-assembly conjugation reactions, Tetrahedron 62: 3248-3258.
- Comuzzi C., Cogoi S., Overhand M., Marel G.A. van der, Overkleeft H.S. & Xodo L. (2006), Synthesis and biological evaluation of new pentaphyrin macrocycles for photodynamic therapy, Journal of Medicinal Chemistry 49: 196-204.
- Risseeuw M.D.P., Grotenbreg G.M., Witte M.D., Tuin A.W., Leeuwenburgh M.A., Marel G.A. van der, Overkleeft H.S. & Overhand M. (2006), The synthesis of cis- and trans-fused bicyclic sugar amino acids, European Journal of Organic Chemistry 17: 3877-3886.
- Cavalli S., Popescu D.C., Tellers E., Vos M.R.J., Pichon B.P., Overhand M., Rapaport H., Sommerdijk N.A.J.M. & Kros A. (2006), Self-organizing beta-sheet lipopeptide monolayers as template for the mineralization of CaCO3, Angewandte Chemie - International Edition in English 45(5): 739-744.
- Vlasie M.D., Comuzzi C., Nieuwendijk A.M.C.H. van den, Prudêncio M., Overhand M. & Ubbink M. (2006), Long-range distance NMR effects in a protein labeled with a lanthanide-DOTA chelate, Chemistry: a European Journal : .
- El Oualid F., Cohen L.H., Marel G.A. van der & Overhand M. (2006), Inhibitors of protein: Geranylgeranyl transferases, Current Medicinal Chemistry 13: 2385-2427.
- Grotenbreg G.M., Buizert A.E.M., Llamas-Saiz A.L., Spalburg E., Hooft P.A.V. van, Neeling A.J., Noort D., Raaij M.J. van, Marel G.A. van der, Overkleeft H.S. & Overhand M. (2006), Beta-Turn modified gramicidin S analogues containing arylated sugar amino acids display antimicrobial and hemolytic activity comparable to the natural product, Journal of the American Chemical Society 128: 7559-7565.
- Grotenbreg G.M., Witte M.D., Hooft P.A.V. van, Spalburg E., Reiß P., Noort D., Neeling A.J., Koert U., Marel G.A. van der, Overkleeft H.S. & Overhand M. (2005), Synthesis and biological evaluation of gramicidin S dimmers, ORGANIC & BIOMOLECULAR CHEMISTRY 3: 233-238.
- Koning M.C. de, Knaap M.S. van der, Petersen L., Elst H. van den, Marel G.A. van der, Overhand M. & Filippov D.V. (2005), Reactivity of PNA thioesters in chemical ligation reactions, SYNLETT 6: 595-598.
- Timmer M.S.M., Verhelst S.H.L., Grotenbreg G.M., Overhand M. & Overkleeft H.S. (2005), Carbohydrates as versatile platforms in the construction of small compound libraries, 77: 1173-1181.
- Cavalli S., Popescu D., Tellers E., Overhand M., Sommerdijk N. & Kros A. (2005), Beta- sheet forming lipopeptides as templates for the mineralization of CaCO3, Polymer Preprints 46: 118-119.
- El Oualid F., Elst H. van den, Leroy I.M., Pieterman E., Cohen L.H., Burm B.E.A., Overkleeft H.S., Marel G.A. van der & Overhand M. (2005), A combinatorial approach toward the generation of ambiphilic peptide-based inhibitors of protein:geranylgeranyl transferase-1, Journal Of Combinatorial Chemistry 7: 703-713.
- Ayres L., Grotenbreg G.M., Marel G.A. van der, Overkleeft H.S., Overhand M. & Hest J.C.M. van (2005), Synthesis and controlled polymerisation of a novel Gramicidin S analogue, Macromolecular Rapid Communications 26: 1336-1340.
- El Oualid F., Baktawar J., Leroy I.M., Elst H. van den, Cohen L.H., Marel G.A. van der, Overkleeft H.S. & Overhand M. (2005), Synthesis and biological evaluation of lipophilic Ca1a2L analogues as potential bisubstrate inhibitors of protein: geranylgeranyl transferase-1, Bioorganic & Medicinal Chemistry 13: 1463-1475.
- Koning M.C. de, Marel G.A. van der & Overhand M. (2003), Synthetic developments towards PNA-peptide conjugates, Current Opinion in Chemical Biology 7: 734-740.
- Tromp R.A., Hoeven M. van der, Amore A., Brussee J., Overhand M., Marel G.A. van der & Gen A. van der (2003), Synthesis of Fmoc-protected (2S,3S)-2-hydroxy-3-amino acids from a furyl substituted chiral cyanohydrin, Tetrahedron Asymmetry 14: 1645-1652.
- Kriek N.M.A.J., Kelly P., Filippov D.V., Meeuwenoord N.J., Marel G.A. van der, Overhand M., Boom J.H. van, Valentijn A. & Overkleeft H.S. (2003), Synthesis of novel tetrahydropyran-based dipeptide isosters by Overman rearrangement of 2,3-didehydroglycosides, European Journal of Organic Chemistry : 2418-2427.
- Kriek N.M.A.J., Hout E. van der, Kelly P., Meijgaarden K.E. van, Geluk A., Ottenhoff T.H.M., Marel G.A. van der, Overhand M., Boom J.H. van, Valentijn A.R.P.M. & Overkleeft H.S. (2003), Synthesis of novel tetrahydron-based dipeptide isosters by Overman rearrangement of 2, 3 didehydroglycosides, European Journal of Organic Chemistry 13: 2418-2427.
- Well R.M. van, Overkleeft H.S., Marel G.A. van der, Bruss D., Thibault G., Groot P.G. de, Boom J.H. van & Overhand M. (2003), Solid-phase synthesis of cyclic RGD-furanoid sugar amino acid peptides as integrin inhibitors, Bioorganic and Medicinal Chemistry Letters 13(3): 331-334.
- Carstensen E.V., Duynstee H.I., Marel G.A. van der, Boom J.H. van, Nielsen J., Overkleeft H.S. & Overhand M. (2003), Synthesis of highly functionalized piperidines via a tandem retro-Michael-2+3-cycloaddition, Journal of Carbohydrate Chemistry 22: 241-252.
- Well R.M. van, Marinelli L., Erkelens K., Marel G.A. van der, Lavecchia A., Overkleeft H.S., Boom J.H. van, Kessler H. & Overhand M. (2003), Synthesis and structural analysis of cyclic oligomers consisting of furanoid and pyranoid epsilon-sugar amino acids, European Journal of Organic Chemistry : 2303-2313.
- Well R.M. van, Marinelli L., Altona C., Erkelens K., Siegal G.D., Raaij M.J. van, Llamas-Saiz A.L., Kessler H., Novellino E., Lavecchia A., Boom J.H. van & Overhand M. (2003), Conformational analysis of furanoid epsilon-sugar amino acid containing cyclic peptides by NMR spectroscopy, molecular dynamics simulation, and X-ray crystallography: Evidence for a novel turn structure, Journal of American Chemical Society 125(36): 10822-10829.
- Kriek N.M.A.J., Hout E. van der, Kelly P., Meijgaarden K.E. van, Geluk A., Ottenhoff T.H.M., Marel G.A. van der, Overhand M., Boom J.H. van, Valentijn A.R.P.M. & Overkleeft H.S. (2003), Synthesis of novel tetrahydropyran-based dipeptide isosters by Overman rearrangement of 2, 3-didehydroglycosides, Eur.J.of Organic Chemistry : 2418-2427.
- Grotenbreg G.M., Spalburg E., Neeling A. de, Marel G.A. van der, Overkleeft H.S., Boom J.H. van & Overhand M. (2003), Synthesis and biological evaluation of novel turn-modified gramicidin S analogues, Bioorganic & Medicinal Chemistry 11: 2835-2841.
- Koning M.C. de, Filippov D.V., Marel G.A. van der, Boom J.H. van & Overhand M. (2003), Synthesis of macrocyclic peptide nucleic acid derivatives via intramolecular chemical ligation, Tetrahedron Letters 44: 7597-7600.
- Well R.M. van, Overkleeft H.S., Boom J.H. van, Coop A., Wang J.B., Wang H.Y., Marel G.A. van der & Overhand M. (2003), Synthesis of novel sugar amino acids by Curtius rearrangement, Journal of Organic Chemistry (JOC) : 1704-1710.
- Well R.M. van, Meijer M.E.A., Overkleeft H.S., Boom J.H. van, Marel G.A. van der & Overhand M. (2003), Synthesis of bridged sugar amino acids: a new entry into conformationally locked delta- and epsilon-amino acids, Tetrahedron 59: 2423-2434.
- Koning M.C. de, Filippov D.V., Meeuwenoord N.J., Overhand M., Marel G.A. van der & Boom J.H. van (2002), An approach to the synthesis of peptide-PNA-peptide conjugates via native ligation, Tetrahedron Letters 43: 8173-8176.
- Eloualid F., Bruining L.D., Leroy I.M., Cohen L.H., Boom J.H. van, Marel G.A. van der, Overkleeft H.S. & Overhand M. (2002), Synthesis and biological evaluation of protein: geranylgeranyltransferase I inhibitors based on the CaaX box: Incorporation of sugar amino acids as dipeptide isosteres, Helvetica Chimica Acta 85: 3455-3472.
- Turner J.J.C., Filippov D.V., Overhand M., Marel G.A. van der & Boom J.H. van (2001), Synthesis of novel amino acid carbohydrate hybrids via Mitsunobu glycosylation of nitrobenzenesulfonamides, Tetrahedron Letters 42: 5763-5767.
- Aguilera Diez M.B., Siegal G.D., Overkleeft H.S., Meeuwenoord N.J., Rutjes F.P.J.T., Hest J.C.M. van, Schoemaker H.E., Marel G.A. van der, Boom J.H. van & Overhand M. (2001), Synthesis and structural analysis of a b-hairpin modified peptide containing a sugar amino acid, European Journal of Organic Chemistry 2001(8): 1541-1574.
- Aguilera Diez M.B., Wolf L.B., Nieczypor P., Rutjes F.P.J.T., Overkleeft H.S., Hest J.C.M. van, Schoemaker H.E., Wang B., Mol J.C., Furstner A., Overhand M., Marel G.A. van der & Boom J.H. van (2001), Synthesis of diaminosuberic acid derivatives via ring-closing alkyne metathesis, Journal of Organic Chemistry (JOC) 66: 3584-3589.
- Koning M.C. de, Filippov D.V., Meeuwenoord N.J., Overhand M., Marel G.A. van der & Boom J.H. van (2001), Synthesis of a PNA-peptide conjugate by chemical ligation, SYNLETT 10: 1516-1518.
- Tromp R.A., Hoeven M. van der, Amore A., Brussee J., Overhand M., Marel G.A. van der & Gen A. van der (2001), Chemoenzymatic synthesis of Fmoc-protected (2S,3S)-2-hydroxy-3-amino acids and their application in the synthesis of an alpha-hydroxylated beta-hexapeptide, Tetrahedron Asymmetry 12: 1109-1112.
- Cohen L.H., Pieterman E.J., Leeuwen R.E.W. van, Overhand M., Burm B.E.A., Marel G.A. van der & Boom J.H. van (2000), Inhibitors of prenylation of Ras and other G-proteins and their application as herapeutics, Biochemical Pharmacology 60: 1061-1068.
- Well R.M. van, Overkleeft H.S., Overhand M., Carstenen E.V., Marel G.A. van der & Boom J.H. van (2000), Parallel synthesis of cyclic sugar amino acid/amino acid hybrid molecules, Tetrahedron Letters 41: 9331-9335.
- Overkleeft H.S., Verhelst S.H.L., Pieterman E.J., Meeuwenoord N.J., Overhand M., Cohen L.H., Marel G.A. van der & Boom J.H. van (1999), Design and synthesis of a protein : farnesyltransferase inhibitor based on sugar amino acids, Tetrahedron Letters 40: 4103.
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