Gregorius Luyten
Hoogleraar Oogheelkunde
- Naam
- Prof.dr. G.P.M. Luyten
- Telefoon
- +31 71 526 6674
- g.p.m.luyten@lumc.nl
Hoogleraar, afdelingshoofd en opleider van de afdeling oogheelkunde van het Leids Universitair Medisch Centrum (LUMC) te Leiden. Lid Raad van Toezicht van Koninklijke VISIO, Stichting Oogheelkunde Rijswijk en Stichting Oogfonds Nederland.
Meer informatie over Gregorius Luyten
Hoogleraar, afdelingshoofd en opleider van de afdeling oogheelkunde van het Leids Universitair Medisch Centrum (LUMC) te Leiden.
Lid Raad van Toezicht van Koninklijke VISIO, Stichting Oogheelkunde Rijswijk en Stichting Oogfonds Nederland.
Oogheelkunde
Prof. dr. G.P.M. Luyten is opgeleid als oogarts en gepromoveerd op het gebied van de oogoncologie. De academische oogheelkundige zorg functioneert in de keten waarbij wij zorg moeten dragen voor de hoogcomplexe zorg. Wij willen zorgdragen dat patiënten de beste zorg kunnen krijgen op de juiste plaats en juiste tijd. Dit vergt een goede samenwerking met de verschillende ketenaanbieders, huisartsen, optometristen, oogartsen en de revalidatiecentra om participatie van patiënten in de maatschappij zo maximaal mogelijk te bevorderen. Het is onze rol in de sterke verbinding van patiëntenzorg, onderwijs en onderzoek steeds te zoeken en te streven naar innovatie en verbetering van de oogzorg, dit te implementeren, dit te onderwijzen en over te dragen aan onze oogheelkundige collega’s zodat we steeds de best oogheelkundige zorg kunnen blijven leveren.
Oogoncologie
Vanuit de kliniek ben ik direct betrokken bij de diagnostiek en behandeling van de patiënten met een oogmelanoom als landelijk verwijscentrum. De onderzoekslijnen zijn de (klinische) uitkomsten en kwaliteit van diagnostiek en behandeling van patiënten met een primair en gemetastaseerd oogmelanoom met als uiteindelijk doel de prognose en kwaliteit van leven van deze patiënten te verbeteren. Huidige lijnen zijn onder andere opzetten van landelijke polikliniek voor het BAP1-tumor-predispositie-syndroom en onderzoek en implementatie van image-guided protonenbestraling.
Dysphotopsie
Patiënten krijgen in toenemende mate klachten van dysphotopsie (negatief en positief) na een succesvol uitgevoerde cataractoperatie (4-18%) wat in veel gevallen niet wordt herkend en erkend door vele oogartsen. Er bestaat geen duidelijk verklaring en oplossing voor deze klachten. In het kader van een Europees gesubsidieerde studie met een high resolution MRI-oogmodel onderzocht met behulp van raytracing technologie hierin een verklaring te vinden. Als landelijk verwijscentrum wordt bij deze patiënten een lenswissel uitgevoerd met een succespercentage tot 80%.
Regeneratieve geneeskunde
De combinatie van topreferente klinische zorg op gebied van kinderoogheelkunde en erfelijke en niet-erfelijke netvliesaandoeningen en toponderzoekers op het gebied van gentherapie en stamcelonderzoek maakt dat de afdeling sterk gaat inzetten om dit onderzoeksgebied. Door de samenwerkingen binnen en buiten het LUMC zowel nationaal als internationaal biedt dit grote kansen om binnen 10 jaar te komen tot klinische toepassingen die grote verschillen gaan maken.
Wetenschappelijke carrière
- Studentonderzoeker afdeling celbiologie genetica (Prof Galjaard), Erasmus Universiteit Rotterdam
- Promotie 16 mei 1996: 'Primary and metastatic uveal melanoma: towards a therapeutic approach'
- Oratie 15 januari 2008: 'Anders leren kijken'
Hoogleraar Oogheelkunde
- Faculteit Geneeskunde
- Divisie 3
- Oogheelkunde
- Klaassen, L.; Jaarsma-Coes, M.G.; Verbist, B.M.; Vu, T.H.K.; Marinkovic, M.; Rasch, C.R.N.; Luyten, G.P.M. & Beenakker, J.W.M. (2022), Automatic three-dimensional magnetic resonance-based measurements of tumour prominence and basal diameter for treatment planning of uveal melanoma, PHYSICS & IMAGING IN RADIATION ONCOLOGY 24: 102-110.
- Rozendal, L.R.W.; Vught, L. van; Luyten, G.P.M. & Beenakker, J.W.M. (2022), The value of static perimetry in the diagnosis and follow-up of negative dysphotopsia, Optometry and Vision Science 99(8): 645-651.
- Wierenga, A.P.A.; Brouwer, N.J.; Gelmi, M.C.; Verdijk, R.M.; Stern, M.H.; Bas, Z.; Malkani, K.; Duinen, S.G. van; Ganguly, A.; Kroes, W.G.M.; Marinkovic, M.; Luyten, G.P.M.; Shields, C.L. & Jager, M.J. (2022), Chromosome 3 and 8q aberrations in uveal melanoma show greater impact on survival in patients with light Iris versus dark iris color, Ophthalmology 129(4): 421-430.
- Haarman, A.E.G.; Tedja, M.S.; Brussee, C.; Enthoven, C.A.; Rijn, G.A. van; Vingerling, J.R.; Keunen, J.E.E.; Boon, C.J.F.; Geerards, A.J.M.; Luyten, G.P.M.; Verhoeven, V.J.M. & Klaver, C.C.W. (2021), Prevalence of myopic macular features in Dutch individuals of European ancestry with high myopia, JAMA Ophthalmology 140(2).
- Marinkovic, M.; Pors, L.J.; Berg, V. van den; Peters, F.P.; Schalenbourg, A.; Zografos, L.; Pica, A.; Hrbacek, J.; Duinen, S.G. van; Vu, T.H.K.; Bleeker, J.C.; Rasch, C.R.N.; Jager, M.J.; Luyten, G.P.M. & Horeweg, N. (2021), Clinical outcomes after international referral of uveal melanoma patients for proton therapy, Cancers 13(24).
- Hassan, M.K.; Fleury, E.; Shamonin, D.; Fonk, L.G.; Marinkovic, M.; Jaarsma-Coes, M.G.; Luyten, G.P.M.; Webb, A.; Beenakker, J.W. & Stoel, B. (2021), An automatic framework to create patient-specific eye models from 3D magnetic resonance images for treatment selection in patients with uveal melanoma, Advances in Radiation Oncology 6(6).
- Vught, L. van; Shamonin, D.P.; Luyten, G.P.M.; Stoel, B.C. & Beenakker, J.W.M. (2021), MRI-based 3D retinal shape determination, BMJ Open Ophthalmology 6(1).
- Ferreira, T.A.; Jaarsma-Coes, M.G.; Marinkovic, M.; Verbist, B.; Verdijk, R.M.; Jager, M.J.; Luyten, G.P.M. & Beenakker, J.W.M. (2021), MR imaging characteristics of uveal melanoma with histopathological validation, Neuroradiology 64.
- Gaurisankar, Z.S.; Rijn, G.A. van; Cheng, Y.Y.Y.; Luyten, G.P.M. & Beenakker, J.W.M. (2021), Two-year results after combined phacoemulsification and iris-fixated phakic intraocular lens removal, Graefe's Archive for Clinical and Experimental Ophthalmology 260.
- Tang, M.C.Y.; Jaarsma-Coes, M.G.; Ferreira, T.A.; Fonk, L.Z.G.; Marinkovic, M.; Luyten, G.P.M. & Beenakker, J.W.M. (2021), A comparison of 3 T and 7 T MRI for the clinical evaluation of uveal melanoma, Journal of Magnetic Resonance Imaging 55(5).
- Jaarsma-Coes, M.G.; Ferreira, T.A.; Houdt, P.J. van; Heide, U.A. van der; Luyten, G.P.M. & Beenakker, J.W.M. (2021), Eye-specific quantitative dynamic contrast-enhanced MRI analysis for patients with intraocular masses, Magnetic Resonance Materials in Physics, Biology and Medicine.
- Souri, Z.; Wierenga, A.P.A.; Kroes, W.G.M.; Velden, P.A. van der; Verdijk, R.M.; Eikmans, M.; Luyten, G.P.M. & Jager, M.J. (2021), LAG3 and its ligands show increased expression in high-risk uveal melanoma, Cancers 13(17).
- Vught, L. van; Dekker, C.E.; Stoel, B.C.; Luyten, G.P.M. & Beenakker, J.W.M. (2021), Evaluation of intraocular lens position and retinal shape in negative dysphotopsia using high-resolution magnetic resonance imaging, Journal of Cataract and Refractive Surgery 47(8): 1032-1038.
- Souri, Z.; Jochemsen, A.G.; Wierenga, A.P.A.; Kroes, W.G.M.; Verdijk, R.M.; Velden, P.A. van der; Luyten, G.P.M. & Jager, M.J. (2021), Expression of HDACs 1, 3 and 8 Is upregulated in the presence of Infiltrating lymphocytes in uveal melanoma, Cancers 13(16).
- Voorde, A.M.W. ten; Wierenga, A.P.A.; Nell, R.J.; Velden, P.A. van der; Luyten, G.P.M.; Verdijk, R.M. & Jager, M.J. (2021), In uveal melanoma, angiopoietin-2 but not angiopoietin-1 is increased in high-risk tumors, providing a potential druggable target, Cancers 13(16).
- Souri, Z.; Wierenga, A.P.A.; Kilic, E.; Brosens, E.; Bohringer, S.; Kroes, W.G.M.; Verdijk, R.M.; Velden, P.A. van der; Luyten, G.P.M. & Jager, M.J. (2021), MiRNAs correlate with HLA expression in uveal melanoma, Cancers 13(16).
- Haarman, A.E.G.; Enthoven, C.A.; Tedja, M.S.; Polling, J.R.; Tideman, J.W.L.; Keunen, J.E.E.; Boon, C.J.F.; Felix, J.F.; Raat, H.; Geerards, A.J.M.; Luyten, G.P.M.; Rijn, G.A. van; Verhoeven, V.J.M. & Klaver, C.C.W. (2021), Phenotypic consequences of the GJD2 risk genotype in myopia development, Investigative Ophthalmology & Visual Science 62(10).
- Rijn, G.A. van; Gaurisankar, Z.S.; Saxena, R.; Gibbes, D.; Jongman, H.P.; Haasnoot, G.W.; Cheng, Y.Y.Y.; Beenakker, J.W.M. & Luyten, G.P.M. (2021), Implantation of an iris-fixated phakic intraocular lens for the correction of hyperopia, Journal of Cataract and Refractive Surgery 47(6): 748-758.
- Brouwer, N.J.; Konstantinou, E.K.; Gragoudas, E.S.; Marinkovic, M.; Luyten, G.P.M.; Kim, I.K.; Jager, M.J. & Vavvas, D.G. (2021), Targeting the YAP/TAZ pathway in uveal and conjunctival melanoma with verteporfin, Investigative Ophthalmology & Visual Science 62(4).
- Nell, R.J.; Menger, N.V.; Versluis, M.; Luyten, G.P.M.; Verdijk, R.M.; Madigan, M.C.; Jager, M.J. & Velden, P.A. van der (2021), Involvement of mutant and wild-type CYSLTR2 in the development and progression of uveal nevi and melanoma, BMC Cancer 21(1).
- Brouwer, N.J.; Marinkovic, M.; Bleeker, J.C.; Luyten, G.P.M. & Jager, M.J. (2021), Anterior Segment OCTA of Melanocytic Lesions of the Conjunctiva and Iris, American Journal of Ophthalmology 222: 137-147.
- Fleury, E.; Trnkova, P.; Erdal, E.; Hassan, M.; Stoel, B.; Jaarma-Coes, M.; Luyten, G.; Herault, J.; Webb, A.; Beenakker, J.W.; Pignol, J.P. & Hoogeman, M. (2021), Three-dimensional MRI-based treatment planning approach for non-invasive ocular proton therapy, Medical Physics 48(3).
- Garg, G.; Finger, P.T.; Kivela, T.T.; Simpson, E.R.; Gallie, B.L.; Saakyan, S.; Amiryan, A.G.; Valskiy, V.; Chin, K.J.; Semenova, E.; Seregard, S.; Fili, M.; Wilson, M.; Haik, B.; Caminal, J.M.; Catala-Mora, J.; Gutierrez, C.; Pelayes, D.E.; Folgar, A.M.; Jager, M.J.; Dogrusoz, M.; Luyten, G.P.M.; Singh, A.D.; Suzuki, S. & AJCC Ophthalmic Oncology Task Forc (2021), Patients presenting with metastases, British Journal of Ophthalmology 106(4).
- Vught, L. van; Beenakker, J.W.M. & Luyten, G.P.M. (2021), Reply to comment on: Distinct differences in anterior chamber configuration and peripheral aberrations in negative dysphotop.
- Roelofsen, C.D.M.; Wierenga, A.P.A.; Duinen, S. van; Verdijk, R.M.; Bleeker, J.; Marinkovic, M.; Luyten, G.P.M. & Jager, M.J. (2020), Five decades of enucleations for uveal melanoma in one center, Ocular Oncology and Pathology 7(2).
- Souri, Z.; Jochemsen, A.G.; Versluis, M.; Wierenga, A.P.A.; Nemati, F.; Velden, P.A. van der; Kroes, W.G.M.; Verdijk, R.M.; Luyten, G.P.M. & Jager, M.J. (2020), HDAC inhibition increases HLA class I expression in uveal melanoma, Cancers 12(12).
- Brouwer, N.J.; Marinkovic, M.; Bleeker, J.C.; Filali, M. el; Stefansson, E.; Luyten, G.P.M. & Jager, M.J. (2020), Retinal oximetry is altered in eyes with choroidal melanoma but not in eyes with choroidal nevi , RETINA, The Journal of Retinal and Vitreous Diseases 40(11): 2207-2215.
- Gaurisankar, Z.S.; Rijn, G.A. van; Haasnoot, G.W.; Verhoeven, V.J.M.; Klaver, C.C.W.; Luyten, G.P.M. & Beenakker, J.W.M. (2020), Long-term longitudinal changes in axial length in the Caucasian myopic and hyperopic population with a phakic intraocular lens, Acta Ophthalmologica 99(4).
- Houtzagers, L.E.; Wierenga, A.P.A.; Ruys, A.A.M.; Luyten, G.P.M. & Jager, M.J. (2020), Iris colour and the risk of developing uveal melanoma, International Journal of Molecular Sciences 21(19).
- Jaarsma-Coes, M.G.; Marinkovic, M.; Astreinidou, E.; Schuurmans, M.S.; Peters, F.P.; Luyten, G.P.M.; Rasch, C.R.N. & Beenakker, J.W.M. (2020), Measuring eye deformation between planning and proton beam therapy position using magnetic resonance imaging, PHYSICS & IMAGING IN RADIATION ONCOLOGY 16: 33-36.
- Gaurisankar, Z.S.; Rijn, G.A. van; Luyten, G.P.M. & Beenakker, J.W.M. (2020), Differences between Scheimpflug and optical coherence tomography in determining safety distances in eyes with an iris-fixating phakic intraocular lens, Graefe's Archive for Clinical and Experimental Ophthalmology 259.
- Brouwer, N.J.; Marinkovic, M.; Peters, F.P.; Hulshof, M.C.C.M.; Pieters, B.R.; Keizer, R.J.W. de; Horeweg, N.; Laman, M.S.; Bleeker, J.C.; Duinen, S.G. van; Jager, M.J.; Creutzberg, C.L. & Luyten, G.P.M. (2020), Management of conjunctival melanoma with local excision and adjuvant brachytherapy, Eye 35.
- Dogrusoz, M.; Brouwer, N.J.; Geus, S.J.R. de; Ly, L.V.; Bohringer, S.; Duinen, S.G. van; Kroes, W.G.M.; Velden, P.A. van der; Haasnoot, G.W.; Marinkovic, M.; Luyten, G.P.M.; Kivela, T.T. & Jager, M.J. (2020), Prognostic factors five years after enucleation for uveal melanoma, Investigative Ophthalmology & Visual Science 61(3).
- Rola, A.C.; Taktak, A.; Eleuteri, A.; Kalirai, H.; Heimann, H.; Hussain, R.; Bonnett, L.J.; Hill, C.J.; Traynor, M.; Jager, M.J.; Marinkovic, M.; Luyten, G.P.M.; Dogrusoz, M.; Kilic, E.; Klein, A. de; Smit, K.; Poppelen, N.M. van; Damato, B.E.; Afshar, A.; Guthoff, R.F.; Scheef, B.O.; Kakkassery, V.; Saakyan, S.; Tsygankov, A.; Mosci, C.; Ligorio, P.; Viaggi, S.; Guin, C.H.D. le; Bornfeld, N.; Bechrakis, N.E. & Coupland, S.E. (2020), Multicenter external validation of the Liverpool uveal melanoma prognosticator online, Cancers 12(2).
- Rijn, G.A. van; Wijnen, C.J.F.; Dooren, B.T.H. van; Cheng, Y.Y.Y.; Beenakker, J.W.M. & Luyten, G.P.M. (2020), Improved interchangeability with different corneal specular microscopes for quantitative endothelial cell analysis, Clinical Ophthalmology 14: 61-70.
- Rijn, G. van; Gaurisankar, Z.S.; Ilgenfritz, A.P.; Lima, J.E.E.; Haasnoot, G.W.; Beenakker, J.W.M.; Cheng, Y.Y.Y. & Luyten, G.P.M. (2020), Middle- and long-term results after iris-fixated phakic intraocular lens implantation in myopic and hyperopic patients: a meta-analysis, Journal of Cataract and Refractive Surgery 46(1): 125-137.
- Fonk, L.G.; Ferreira, T.A.; Webb, A.G.; Luyten, G.P.M. & Beenakker, J.W.M. (2020), The economic value of MR-imaging for uveal melanoma, Clinical Ophthalmology 14: 1135-1143.
- Gaurisankar, Z.S.; Rijn, G.A. van; Lima, J.E.E.; Ilgenfritz, A.P.; Cheng, Y.; Haasnoot, G.W.; Luyten, G.P.M. & Beenakker, J.W.M. (2019), Correlations between ocular biometrics and refractive error: A systematic review and meta-analysis, Acta Ophthalmologica 97(8): 735-743.
- Gaurisankar, Z.S.; Rijn, G.A. van; Luyten, G.P.M. & Berg, T.J.T.P. van den (2019), Straylight As The Result Of Refractive Correction, Clinical Ophthalmology 13: 2195-2201.
- Wierenga, A.P.A.; Cao, J.F.; Mouthaan, H.; Weeghel, C. van; Verdijk, R.M.; Duinen, S.G. van; Kroes, W.G.M.; Dogrusoz, M.; Marinkovic, M.; Burg, S.S.H. van der; Luyten, G.P.M. & Jager, M.J. (2019), Aqueous Humor Biomarkers Identify Three Prognostic Groups in Uveal Melanoma, Investigative Ophthalmology & Visual Science 60(14): 4740-4747.
- Dogrusoz, M.; Trasel, A.R.; Cao, J.F.; Colak, S.; Pelt, S.I. van; Kroes, W.G.M.; Teunisse, A.E.A.S.; Alsafadi, S.; Duinen, S.G. van; Luyten, G.P.M.; Velden, P.A. van der; Amaro, A.; Pfeffer, U.; Jochemsen, A.G. & Jager, M.J. (2019), Differential Expression of DNA Repair Genes in Prognostically-Favorable versus Unfavorable Uveal Melanoma, Cancers 11(8).
- Weeghel, C. van; Wierenga, A.P.A.; Versluis, M.; Hall, T. van; Velden, P.A. van der; Kroes, W.G.M.; Pfeffer, U.; Luyten, G.P.M. & Jager, M.J. (2019), Do GNAQ and GNA11 Differentially Affect Inflammation and HLA Expression in Uveal Melanoma?, Cancers 11(8).
- Chau, C.; Doorn, R. van; Poppelen, N.M. van; Stoep, N. van der; Mensenkamp, A.R.; Sijmons, R.H.; Paassen, B.W. van; Ouweland, A.M.W. van den; Naus, N.C.; Hout, A.H. van der; Potjer, T.P.; Bleeker, F.E.; Wevers, M.R.; Hest, L.P. van; Jongmans, M.C.J.; Marinkovic, M.; Bleeker, J.C.; Jager, M.J.; Luyten, G.P.M. & Nielsen, M. (2019), Families with BAP1-Tumor Predisposition Syndrome in The Netherlands: Path to Identification and a Proposal for Genetic Screening Guidelines, Cancers 11(8).
- Souri, Z.; Wierenga, A.P.A.; Weeghel, C. van; Velden, P.A. van der; Kroes, W.G.M.; Luyten, G.P.M.; Burg, S.H. van der; Jochemsen, A.G. & Jager, M.J. (2019), Loss of BAP1 Is Associated with Upregulation of the NFkB Pathway and Increased HLA Class I Expression in Uveal Melanoma, Cancers 11(8).
- Brouwer, N.J.; Marinkovic, M.; Luyten, G.P.M.; Shields, C.L. & Jager, M.J. (2019), Pigmentation of conjunctival melanoma recurrences and outcome, Graefe's Archive for Clinical and Experimental Ophthalmology 257(8): 1783-1788.
- Wierenga, A.P.A.; Gezgin, G.; Beelen, E. van; Eikmans, M.; Spruyt-Gerritse, M.; Brouwer, N.J.; Versluis, M.; Verdijk, R.M.; Duinen, S.G. van; Marinkovic, M.; Luyten, G.P.M. & Jager, M.J. (2019), Soluble HLA in the Aqueous Humour of Uveal Melanoma Is Associated with Unfavourable Tumour Characteristics, Cancers 11(8).
- Jaarsma-Coes, M.G.; Ferreira, T.A.; Luyten, G.P.M. & Beenakker, J.W.M. (2019), Reaction on "Ocular ultrasound versus MRI in the detection of extrascleral extension in a patient with choroidal melanoma", BMC Ophthalmology 19(1).
- Brouwer, N.J.; Wierenga, A.P.A.; Gezgin, G.; Marinkovic, M.; Luyten, G.P.M.; Kroes, W.G.M.; Versluis, M.; Velden, P.A. van der; Verdijk, R.M. & Jager, M.J. (2019), Ischemia Is Related to Tumour Genetics in Uveal Melanoma, Cancers 11(7).
- Brouwer, N.J.; Gezgin, G.; Wierenga, A.P.A.; Bronkhorst, I.H.G.; Marinkovic, M.; Luyten, G.P.M.; Versluis, M.; Kroes, W.G.M.; Velden, P.A. van der; Verdijk, R.M. & Jager, M.J. (2019), Tumour Angiogenesis in Uveal Melanoma Is Related to Genetic Evolution, Cancers 11(7).
- Brouwer, N.J.; Marinkovic, M.; Luyten, G.P.M.; Shields, C.L. & Jager, M.J. (2019), Lack of tumour pigmentation in conjunctival melanoma is associated with light iris colour and worse prognosis, British Journal of Ophthalmology 103(3): 332-337.
- Mohabati, D.; Rijssen, T.J. van; Dijk, E.H.C. van; Luyten, G.R.P.M.; Missotten, T.O.; Hoyng, C.B.; Yzer, S. & Boon, C.J.F. (2018), Clinical characteristics and long-term visual outcome of severe phenotypes of chronic central serous chorioretinopathy, Clinical Ophthalmology 12: 1061-1070.
- Walpole, S.; Pritchard, A.L.; Cebulla, C.M.; Pilarski, R.; Stautberg, M.; Davidorf, F.H.; Fouchardiere, A. de la; Cabaret, O.; Golmard, L.; Stoppa-Lyonnet, D.; Garfield, E.; Njauw, C.N.; Cheung, M.; Turunen, J.A.; Repo, P.; Jarvinen, R.S.; Doorn, R. van; Jager, M.J.; Luyten, G.P.M.; Marinkovic, M.; Chau, C.; Potrony, M.; Hoiom, V.; Helgadottir, H.; Pastorino, L.; Bruno, W.; Andreotti, V.; Dalmasso, B.; Ciccarese, G.; Queirolo, P.; Mastracci, L.; Wadt, K.; Kiilgaard, J.F.; Speicher, M.R.; Poppelen, N. van; Kilic, E.; Al-Jamal, R.T.; Dianzani, I.; Betti, M.; Bergmann, C.; Santagata, S.; Dahiya, S.; Taibjee, S.; Burke, J.; Poplawski, N.; O'Shea, S.J.; Newton-Bishop, J.; Adlard, J.; Adams, D.J.; Lane, A.M.; Kim, I.; Klebe, S.; Racher, H.; Harbour, J.W.; Nickerson, M.L.; Murali, R.; Palmer, J.M.; Howlie, M.; Symmons, J.; Hamilton, H.; Warrier, S.; Glasson, W.; Johansson, P.; Robles-Espinoza, C.D.; Ossio, R.; Klein, A. de; Puig, S.; Ghiorzo, P.; Nielsen, M.; Kivela, T.T.; Tsao, H.; Testa, J.R.; Gerami, P.; Stern, M.H.; Bressac-de Paillerets, B.; Abdel-Rahman, M.H. & Hayward, N.K. (2018), Comprehensive Study of the Clinical Phenotype of Germline BAP1 Variant-Carrying Families Worldwide, JNCI: Journal of the National Cancer Institute 110(12): 1328-1341.
- Brouwer, N.J.; Marinkovic, M.; Jochems, A.; Kapiteijn, E.W.; Duinen, S.G. van; Haeseker, B.I.; Jager, M.J. & Luyten, G.P.M. (2018), Conjunctival Metastasis of a Cutaneous Melanoma, Ocular Oncology and Pathology 4(2): 107-111.
- Ferreira, T.A.; Saraiva, P.; Genders, S.W.; Buchem, M.V.; Luyten, G.P.M. & Beenakker, J.W. (2018), CT and MR imaging of orbital inflammation, Neuroradiology 60(12): 1253-1266.
- Lange, M.J. de; Nell, R.J.; Lalai, R.N.; Versluis, M.; Jordanova, E.S.; Luyten, G.P.M.; Jager, M.J.; Burg, S.H. van der; Zoutman, W.H.; Hall, T. van & Velden, P.A. van der (2018), Digital PCR-Based T-cell Quantification-Assisted Deconvolution of the Microenvironment Reveals that Activated Macrophages Drive Tumor Inflammation in Uveal Melanoma, Molecular Cancer Research 16(12): 1902-1911.
- Beek, J.G.M. van; Buitendijk, G.H.S.; Timman, R.; Muller, K.; Luyten, G.P.M.; Paridaens, D.; Naus, N.C. & Kilic, E. (2018), Quality of life: fractionated stereotactic radiotherapy versus enucleation treatment in uveal melanoma patients, Acta Ophthalmologica 96(8): 841-848.
- Brouwer, N.J.; Genders, S.W.; Marinkovic, M.; Duinen, S.G. van; Jager, M.J. & Luyten, G.P.M. (2018), Two Late Recurrences of Conjunctival Melanoma, Ocular Oncology and Pathology 5(4): 262-266.
- Dijk, E.H.C. van; Kruit, W.H.J.; Jager, M.J.; Luyten, G.P.M.; Vingerling, J.R. & Boon, C.J.F. (2018), Pimasertib-associated ophthalmological adverse events, Acta Ophthalmologica 96(7): 712-718.
- Brouwer, N.J.; Marinkovic, M.; Duinen, S.G. van; Bleeker, J.C.; Jager, M.J. & Luyten, G.P.M. (2018), Treatment of conjunctival melanoma in a Dutch referral centre, British Journal of Ophthalmology 102(9): 1277-1282.
- Marinkovic, M.; Horeweg, N.; Laman, M.S.; Bleeker, J.C.; Ketelaars, M.; Peters, F.P.; Luyten, G.P.M. & Creutzberg, C.L. (2018), Ruthenium-106 brachytherapy for iris and iridociliary melanomas, British Journal of Ophthalmology 102(8): 1154-1159.
- Wouters, M.W.; Michielin, O.; Bastiaannet, E.; Beishon, M.; Catalano, O.; Marmol, V.; Delgado-Bolton, R.; Dendale, R.; Trill, M.D.; Ferrari, A.; Forsea, A.M.; Kreckel, H.; Lovey, J.; Luyten, G.; Massi, D.; Mohr, P.; Oberst, S.; Pereira, P.; Prata, J.P.P.; Rutkowski, P.; Saarto, T.; Sheth, S.; Spurrier-Bernard, G.; Vuoristo, M.S.; Costa, A. & Naredi, P. (2018), ECCO essential requirements for quality cancer care: Melanoma, Critical Reviews in Oncology/Hematology 122: 164-178.
- Brouwer, N.J.; Luyten, G.P.M.; Duinen, S.G. van; Jager, M.J. & Marinkovic, M. (2017), Multiple Pigmented Conjunctival Lesions following Intravitreal Injections in a Patient with Uveal Melanoma, Ocular Oncology and Pathology 3(2): 113-116.
- Gezgin, G.; Dogrusoz, M.; Essen, T.H. van; Kroes, W.G.M.; Luyten, G.P.M.; Velden, P.A. van der; Walter, V.; Verdijk, R.M.; Hall, T. van; Burg, S.H. van der & Jager, M.J. (2017), Genetic evolution of uveal melanoma guides the development of an inflammatory microenvironment, Cancer Immunology, Immunotherapy 66(7): 903-912.
- Gezgin, G.; Luk, S.J.; Cao, J.F.; Dogrusoz, M.; Steen, D.M. van der; Hagedoorn, R.S.; Krijgsman, D.; Velden, P.A. van der; Field, M.G.; Luyten, G.P.M.; Szuhai, K.; Harbour, J.W.; Jordanova, E.S.; Heemskerk, M.H.M. & Jager, M.J. (2017), PRAME as a Potential Target for Immunotherapy in Metastatic Uveal Melanoma, JAMA Ophthalmology 135(6).
- Fonk, L.G.; Verstegen, M.; Teeuwisse, W.; Ferreira, T.; Furth, W. van; Pereira, A.; Webb, A.; Notting, I.; Luyten, G. & Beenakker, J.W. (2017), MR imaging of the optic nerve and chiasm at 7 Tesla improves lesion detection for Neuro-Ophthalmic conditions compared to conventional clinical field strengths, Acta Ophthalmologica 95: 27-27.
- Vught, L. van; Hervella, L.; Tabernero, J.; Shamonin, D.P.; Webb, A.G.; Artal, P.; Luyten, G.P.M. & Beenakker, J.W.M. (2017), Personalized eye-models for optical assessment of ocular conditions, Acta Ophthalmologica 95: 8-9.
- Beenakker, J.W.M.; Vught, L. van; Meel, R. de; Burakiewicz, J.; Genders, S.; Jager, M.; Luyten, G.P.M.; Verschuuren, J.J.G.M.; Kan, H.E. & Notting, I.C. (2017), Quantitative MRI of extra-ocular muscles in the clinical evaluation of systemic diseases, Acta Ophthalmologica 95: 12-13.
- Luyten, G.; Marinkovic, M.; Sommers, L.; Horeweg, N.; Fiocco, M.; Bleeker, J. & Creutzberg, C.L. (2017), Ruthenium-106 brachytherapy for uveal melanoma without transpupillary thermotherapy: similar efficacy with improved visual outcome, Acta Ophthalmologica 95: 15-15.
- Jong, Y. de; Haverkort, M.E.; Sorge, A.J. van; Jansen, C.; Luyten, G.P.M. & Joosse, M. (2017), A translucent vascularised iris granuloma in a patient with secondary syphilis, Lancet Infectious Diseases 17(3): 255-256.
- Dogrusoz, M.; Bagger, M.; Duinen, S.G. van; Kroes, W.G.; Ruivenkamp, C.A.L.; Bohringer, S.; Andersen, K.K.; Luyten, G.P.M.; Kiilgaard, J.F. & Jager, M.J. (2017), The Prognostic Value of AJCC Staging in Uveal Melanoma Is Enhanced by Adding Chromosome 3 and 8q Status, Investigative Ophthalmology & Visual Science 58(2).
- Leede, E.M. de; Burgmans, M.C.; Kapiteijn, E.; Luyten, G.P.M.; Jager, M.J.; Tijl, F.G.J.; Hartgrink, H.H.; Grunhagen, D.J.; Rothbarth, J.; Veldea, C.J.H. van de; Verhoef, C. & Vahrmeijer, A.L. (2016), Isolated (hypoxic) hepatic perfusion with high-dose chemotherapy in patients with unresectable liver metastases of uveal melanoma: results from two experienced centres, Melanoma Research 26(6): 588-594.
- Kalirai, H.; Shahidipour, H.; Moss, D.; Coupland, S.E. & Luyten, G.P.M. (2016), Use of the Chick Embryo Model in Uveal Melanoma (vol 1, pg 133, 2015), Ocular Oncology and Pathology 2(1): 59-59.
- Tideman, J.W.L.; Snabel, M.C.C.; Tedja, M.S.; Rijn, G.A. van; Wong, K.T.; Kuijpers, R.W.A.M.; Vingerling, J.R.; Hofman, A.; Buitendijk, G.H.S.; Keunen, J.E.E.; Boon, C.J.F.; Geerards, A.J.M.; Luyten, G.P.M.; Verhoeven, V.J.M. & Klaver, C.C.W. (2016), Association of Axial Length With Risk of Uncorrectable Visual Impairment for Europeans With Myopia, JAMA Ophthalmology 134(12): 1355-1363.
- Marinkovic M., Horeweg N., Fiocco M., Peters F.P., Sommers L.W., Laman M.S., Bleeker J.C., Ketelaars M., Luyten G.P.M. & Creutzberg C.L. (2016), Ruthenium-106 brachytherapy for choroidal melanoma without transpupillary thermotherapy: Similar efficacy with improved visual outcome, European Journal of Cancer 68: 106-113.
- Marinkovic, M.; Horeweg, N.; Fiocco, M.; Peters, F.P.; Sommers, L.W.; Laman, M.S.; Bleeker, J.C.; Ketelaars, M.; Luyten, G.P.M. & Creutzberg, C.L. (2016), Ruthenium-106 brachytherapy for choroidal melanoma without transpupillary thermotherapy: Similar efficacy with improved visual outcome, European Journal of Cancer 68: 106-113.
- Essen, T.H. van; Pelt, S.I. van; Bronkhorst, I.H.G.; Versluis, M.; Nemati, F.; Laurent, C.; Luyten, G.P.M.; Hall, T. van; Elsen, P.J. van den; Decaudin, D. & Jager, M.J. (2016), Upregulation of HLA Expression in Primary Uveal Melanoma by Infiltrating Leukocytes, PLoS ONE 11(10).
- Dogrusoz, M.; Bagger, M.; Duinen, S.G. van; Kroes, W.G.M.; Bohringer, S.; Luyten, G.P.M.; Kiilgaard, J.F. & Jager, M.J. (2016), AJCC Staging and Chromosome 3 and 8 status complement each other regarding prognostic value in Uveal Melanoma, Investigative Ophthalmology & Visual Science 57(12).
- Verhoeven, V.J.M.; Snabel, M.C.C.; Rijn, G.A. van; Buitendijk, G.H.S.; Vvong, K.T.; Keunen, J.E.E.; Boon, C.J.F.; Geerards, A.J.M.; Luyten, G.P.M. & Klaver, C.C.W. (2016), Axial length and visual function in high myopia, Investigative Ophthalmology & Visual Science 57(12).
- Beenakker, J.W.; Ferreira, T.; Soemarwoto, K.; Genders, S.; Teeuwisse, W.; Webb, A. & Luyten, G.P.M. (2016), Clinical evaluation of ultra high field MRI for three-dimensional visualization of tumour size in uveal melanoma patients, with direct relevance to treatment planning, Investigative Ophthalmology & Visual Science 57(12).
- Gezgin, G.; Luk, S.J.; Cao, J.F.; Dogrusoz, M.; Krijgsman, D.; Velden, P.A. van der; Luyten, G.P.M.; Harbour, J.W.; Jordanova, E.S.; Heemskerk, M.H.M. & Jager, M.J. (2016), PRAME: a potential target for immunotherapy in uveal melanoma, Investigative Ophthalmology & Visual Science 57(12).
- Beenakker, J.W.M.; Ferreira, T.A.; Soemarwoto, K.P.; Genders, S.W.; Teeuwisse, W.M.; Webb, A.G. & Luyten, G.P.M. (2016), Clinical evaluation of ultra-high-field MRI for three-dimensional visualisation of tumour size in uveal melanoma patients, with direct relevance to treatment planning, Magnetic Resonance Materials in Physics, Biology and Medicine 29(3): 571-577.
- Jongman, H.P.; Marinkovic, M.; Notting, I.; Koetsier, L.; Swart, W.; Schalij-Delfos, N.E.; Bleeker, J.; Jager, M.J. & Luyten, G.P.M. (2016), Donor sclera-wrapped acrylic orbital implants following enucleation: experience in 179 patients in the Netherlands, Acta Ophthalmologica 94(3): 253-256.
- Dijk, E.H.C. van; Duits, D.E.M.; Versluis, M.; Luyten, G.P.M.; Bergen, A.A.B.; Kapiteijn, E.W.; Lange, M.J. de; Boon, C.J.F. & Velden, P.A. van der (2016), Loss of MAPK Pathway Activation in Post-Mitotic Retinal Cells as Mechanism in MEK Inhibition-Related Retinopathy in Cancer Patients, Medicine 95(18).
- Essen, T.H. van; Zijl, L. van; Possemiers, T.; Mulder, A.A.; Zwart, S.J.; Chou, C.H.; Lin, C.C.; Lai, H.J.; Luyten, G.P.M.; Tassignon, M.J.; Zakaria, N.; Ghalbzouri, A. el & Jager, M.J. (2016), Biocompatibility of a fish scale-derived artificial cornea: Cytotoxicity, cellular adhesion and phenotype, and in vivo immunogenicity, Biomaterials 81: 36-45.
- Nielsen, M.; Dogrusoz, M.; Bleeker, J.C.; Kroes, W.G.; Asperen, C.J. van; Marinkovic, M.; Luyten, G.P. & Jager, M.J. (2015), The genetic basis of uveal melanoma (vol 38, pg 516, 2015), Journal Fran�ais D'Ophtalmologie 38(10): 1021-1021.
- Kalirai, H.; Shahidipour, H.; Coupland, S.E. & Luyten, G.P.M. (2015), Use of the Chick Embryo Model in Uveal Melanoma, Ocular Oncology and Pathology 1(3): 133-140.
- Lange, M.J. de; Pelt, S.I. van; Versluis, M.; Jordanova, E.S.; Kroes, W.G.M.; Ruivenkamp, C.; Burg, S.H. van der; Luyten, G.P.M.; Hall, T. van; Jager, M.J. & Velden, P.A. van der (2015), Heterogeneity revealed by integrated genomic analysis uncovers a molecular switch in malignant uveal melanoma, Oncotarget 6(35): 37824-37835.
- Jager, M.J.; Krijgsman, D.; Luyten, G.P.M.; Luk, S.J.; Velden, P. van der & Heemskerk, M.H.M. (2015), Selecting uveal melanoma for PRAME-TCR T cell immunotherapy, Acta Ophthalmologica 93.
- Dogrusoz, M.; Kroes, W.G.M.; Duinen, S.G. van; Creutzberg, C.L.; Versluis, M.; Bleeker, J.C.; Marinkovic, M.; Luyten, G.P.M. & Jager, M.J. (2015), Radiation Treatment Affects Chromosome Testing in Uveal Melanoma, Investigative Ophthalmology & Visual Science 56(10): 5956-5964.
- Dijk, E.H.C. van; Herpen, C.M.L. van; Marinkovic, M.; Haanen, J.B.A.G.; Amundson, D.; Luyten, G.P.M.; Jager, M.J.; Kapiteijn, E.H.W.; Keunen, J.E.E.; Adamus, G. & Boon, C.J.F. (2015), Serous Retinopathy Associated with Mitogen-Activated Protein Kinase Kinase Inhibition (Binimetinib) for Metastatic Cutaneous and Uveal Melanoma, Ophthalmology: Journal of The American Academy of Ophthalmology 122(9): 1907-1916.
- Lange, M.J. de; Razzaq, L.; Versluis, M.; Verlinde, S.; Dogrusoz, M.; Bohringer, S.; Marinkovic, M.; Luyten, G.P.M.; Keizer, R.J.W. de; Gruijl, F.R. de; Jager, M.J. & Velden, P.A. van der (2015), Distribution of GNAQ and GNA11 Mutation Signatures in Uveal Melanoma Points to a Light Dependent Mutation Mechanism, PLoS ONE 10(9).
- Lange, M.J. de; Razzaq, L.; Versluis, M.; Verlinde, S.; Dogrusoz, M.; Bohringer, S.; Marinkovic, M.; Luyten, G.P.M.; Keizer, R.J.W. de; Gruijl, F.R. de; Jager, M.J. & Velden, P.A. van der (2015), Distribution of GNAQ and GNA11 Mutation Signatures in Uveal Melanoma Points to a Light Dependent Mutation Mechanism, PLoS ONE 10(9).
- Rodenburg-Vandenbussche, S.; Pieterse, A.H.; Kroonenberg, P.M.; Scholl, I.; Weijden, T. van der; Luyten, G.P.M.; Kruitwagen, R.F.P.M.; Ouden, H. den; Carlier, I.V.E.; Vliet, I.M. van; Zitman, F.G. & Stiggelbout, A.M. (2015), Dutch Translation and Psychometric Testing of the 9-Item Shared Decision Making Questionnaire (SDM-Q-9) and Shared Decision Making Questionnaire-Physician Version (SDM-Q-Doc) in Primary and Secondary Care, PLoS ONE 10(7).
- Beenakker, J.W.M.; Shamonin, D.P.; Webb, A.G.; Stoel, B.C. & Luyten, G.P.M. (2015), Improved 3D retinal shape models with high-field MRI, Investigative Ophthalmology & Visual Science 56(7).
- Dogrusoz, M.; Kroes, W.G.M.; Duinen, S. van; Creutzberg, C.L.; Versluis, M.; Bleeker, J.C.; Marinkovic, M.; Luyten, G.P.M. & Jager, M.J. (2015), Irradiation enhances chromosomal aberrations in uveal melanoma, Investigative Ophthalmology & Visual Science 56(7).
- Gezgin, G.; Bronkhorst, I.H.G.; Essen, T.H. van; Pelt, S. van; Verdijk, R.M.; Velden, P.A. van der; Luyten, G.P.M.; Hall, T. van; Burg, S.H. van der & Jager, M.J. (2015), Loss of BAPI expression is associated with increased angiogenesis in uveal melanoma, Investigative Ophthalmology & Visual Science 56(7).
- State, M.; Beenakker, J.W.M.; Shamonin, D.P.; Mooren, M. van der; Stoel, B.C.; Webb, A.G.; Luyten, G.P.M. & Piers, P.A. (2015), Retinal shape assessment in young phakic eyes by a combined partial coherence interferometry - magnetic resonance imaging approach, Investigative Ophthalmology & Visual Science 56(7).
- Boon, C.J.F.; Dijk, E.H.C. van; Herpen, C.M.L. van; Marinkovic, M.; Amundson, D.; Luyten, G.P.M.; Jager, M.J.; Kapiteijn, E.H.W.; Keunen, J.E.E. & Adamus, G. (2015), Serous retinopathy associated with MEK inhibition (binimetinib) for metastatic cutaneous and uveal melanoma, Investigative Ophthalmology & Visual Science 56(7).
- Nielsen, M.; Dogrusoz, M.; Bleeker, J.C.; Kroes, W.G.; Asperen, C.A. van; Marinkovic, M.; Luyten, G.P.M. & Jager, M.J. (2015), The genetic basis of uveal melanoma, Journal Fran�ais D'Ophtalmologie 38(6): 516-521.
- Versluis, M.; Lange, M.J. de; Pelt, S.I. van; Ruivenkamp, C.A.L.; Kroes, W.G.M.; Cao, J.F.; Jager, M.J.; Luyten, G.P.M. & Velden, P.A. van der (2015), Digital PCR Validates 8q Dosage as Prognostic Tool in Uveal Melanoma, PLoS ONE 10(3).
- Beenakker, J.W.M.; Shamonin, D.P.; Webb, A.G.; Luyten, G.P.M. & Stoel, B.C. (2015), Automated Retinal Topographic Maps Measured With Magnetic Resonance Imaging, Investigative Ophthalmology & Visual Science 56(2): 1033-1039.
- Essen, T.H. van; Pelt, S.I. van; Versluis, M.; Bronkhorst, I.H.G.; Duinen, S.G. van; Marinkovic, M.; Kroes, W.G.M.; Ruivenkamp, C.A.L.; Shukla, S.; Klein, A. de; Kilic, E.; Harbour, J.W.; Luyten, G.P.M.; Velden, P.A. van der; Verdijk, R.M. & Jager, M.J. (2014), Prognostic parameters in uveal melanoma and their association with BAP1 expression, British Journal of Ophthalmology 98(12): 1738-1743.
- Bronkhorst, I.H.G.; Jehs, T.M.L.; Dijkgraaf, E.M.; Luyten, G.P.M.; Velden, P.A. van der; Burg, S.H. van der & Jager, M.J. (2014), Effect of Hypoxic Stress on Migration and Characteristics of Monocytes in Uveal Melanoma, JAMA Ophthalmology 132(5): 614-621.
- Roukens, A.H.; Kroep, J.R.; Marinkovic, M.; Nout, R.A.; Bovee, J.V.M.G.; Vasylenko, Y.; Gelderblom, H. & Lutyen, G.P.M. (2014), Primary Ewing sarcoma of the iris, Lancet 383(9913): 256-256.
- Beenakker, J.W.M.; Rijn, G.A. van; Luyten, G.P.M. & Webb, A.G. (2013), High-resolution MRI of uveal melanoma using a microcoil phased array at 7 T, NMR in Biomedicine 26(12): 1864-1869.
- Rijn, G.A. van; Snoek, C.; Joosse, M.; Saxena, R. & Luyten, G.P.M. (2013), Implantation of phakic intraocular lens in 3 patients with oculocutaneous albinism, Journal of Cataract and Refractive Surgery 39(10): 1604-1608.
- Bronkhorst, I.H.G.; Jehs, T.M.L.; Dijkgraaf, E.M.; Luyten, G.P.M.; Velden, P.A. van der; Burg, S.H. van der & Jager, M.J. (2013), Effect of hypoxic stress on induction and plasticity of tumor-induced immune cells in uveal melanoma, Acta Ophthalmologica 91.
- Pelt, S. van; Essen, T.H. van; Bronkhorst, I.H.G.; Versluis, M.; Luyten, G.P.M.; Hall, T. van; Elsen, P.J. van den; Velden, P.A. van & Jager, M.J. (2013), Gain of chromosome 6 status does not influence HLA-expression in uveal melanoma.
- Geus, S.J.R. de; Jager, M.J.; Luyten, G.P.M. & Dijkman, G. (2013), Shifting exudative age-related macular degeneration patients to ranibizumab after insufficient response to bevacizumab, Acta Ophthalmologica 91(5): E411-E413.
- Essen, T.H. van; Zijl, L. van; Sparks, S.J.; Chen, G.; Lin, C.C.; Lai, H.J.; Luyten, G.P.M.; Ghalbzouri, A.E.L. & Jager, M.J. (2013), Suitability of a fish scale-derived collagen matrix (FSCM) as artificial cornea, Acta Ophthalmologica 91.
- Essen, T.H. van; Lin, C.C.; Hussain, A.K.; Maas, S.; Lai, H.J.; Linnartz, H.; Berg, T.J.T.P. van den; Salvatori, D.C.F.; Luyten, G.P.M. & Jager, M.J. (2013), A Fish Scale-Derived Collagen Matrix as Artificial Cornea in Rats: Properties and Potential, Investigative Ophthalmology & Visual Science 54(5): 3224-3233.
- Vu, T.H.K.; Bronkhorst, I.H.G.; Versluis, M.; Marinkovic, M.; Duinen, S.G. van; Vrolijk, J.; Luyten, G.P.M. & Jager, M.J. (2013), Analysis of Inflammatory Cells in Uveal Melanoma after Prior Irradiation, Investigative Ophthalmology & Visual Science 54(1): 360-369.
- el Filali M, van der Velden PA, Luyten GP & Jager MJ (2012), Anti-angiogenic therapy in uveal melanoma., Developments in Ophthalmology 49: 117-36.
- Filali, M. el; Ly, L.V.; Luyten, G.P.M.; Versluis, M.; Grossniklaus, H.E.; Velden, P.A. van der & Jager, M.J. (2012), Bevacizumab and intraocular tumors: an intriguing paradox., Molecular Vision 18: 2454-67.
- Lange, J. de; Teunisse, A.F.A.S.; Verlaan-de Vries, M.; Lodder, K.; Lam, S.; Luyten, G.P.M.; Bernal, F.; Jager, M.J. & Jochemsen, A.G. (2012), High levels of Hdmx promote cell growth in a subset of uveal melanomas., American Journal of Cancer Research 2(5): 492-507.
- Razzaq, L.; Marinkovic, M.; Jager, M.J.; Bleeker, J.; Luyten, G.P.M. & Keizer, R.J.W. de (2012), Corneal endothelial cell density after ruthenium plaque radiation therapy for iris melanoma patients.
- Nagarkatti-Gude, N.; Bronkhorst, I.H.G.; Duinen, S.G. van; Luyten, G.P.M. & Jager, M.J. (2012), Cytokines and Chemokines in the Vitreous Fluid of Eyes with Uveal Melanoma, Investigative Ophthalmology & Visual Science 53(11): 6748-6755.
- Bronkhorst, I.H.G.; Vu, T.H.K.; Jordanova, E.S.; Luyten, G.P.M.; Burg, S.H. van der & Jager, M.J. (2012), Different Subsets of Tumor-Infiltrating Lymphocytes Correlate with Macrophage Influx and Monosomy 3 in Uveal Melanoma, Investigative Ophthalmology & Visual Science 53(9): 5370-5378.
- Rijn, G.A. van; Mourik, J.E.M.; Teeuwisse, W.M.; Luyten, G.P.M. & Webb, A.G. (2012), Magnetic Resonance Compatibility of Intraocular Lenses Measured at 7 Tesla, Investigative Ophthalmology & Visual Science 53(7): 3449-3453.
- Essen, T.H. van; Bronkhorst, I.H.G.; Maat, W.; Verduyn, W.; Roelen, D.L.; Luyten, G.P.M. & Jager, M.J. (2012), A Comparison of HLA Genotype with Inflammation in Uveal Melanoma, Investigative Ophthalmology & Visual Science 53(6): 2640-2646.
- Vlaskamp M, de Wolff-Rouendaal D, Jansen PM & Luyten GP (2012), Concomitant choroidal melanoma and non-hodgkin lymphoma in two adult patients: case report., Case Reports in Ophthalmology 3(2): 209-13.
- Vries, F.R. de; Notting, I.C.; Marinkovic, M.; Schalij-Delfos, N.E. & Luyten, G.P.M. (2012), Complications due to bovine pericardium used to cover acrylic implants after enucleation and tubes of aqueous devices., Eye 26(2): 336.
- Muller, K.; Naus, N.; Nowak, P.J.C.M.; Schmitz, P.I.M.; Pan, C. de; Santen, C.A. van; Marijnissen, J.P.; Paridaens, D.A.; Levendag, P.C. & Luyten, G.P.M. (2012), Fractionated stereotactic radiotherapy for uveal melanoma, late clinical results, Radiotherapy and Oncology 102(2): 219-224.
- Razzaq L, Marinkovic M, Swart W, van Duinen SG, Keunen JE & Luyten GP (2012), Fuchs' adenoma of the choroid simulating a choroidal hemangioma., Case Reports in Ophthalmology 3(1): 83-6.
- Razzaq, L.; Semenova, E.A.; Marinkovic, M.; Keizer, R.J.W. de; Duinen, S.G. van & Luyten, G.P.M. (2011), Mesectodermal Suprauveal Iridociliary Leiomyoma: Transscleral Excision Without Postoperative Iris Defect, Archives of Ophthalmology -New Series- 129(12): 1635-1637.
- Kamar, S.; Vervaet, C.; Luyten, G.P.M. & Jager, M.J. (2011), Pancorneal contact lens with a toric edge: a new concept in keratoconus., European Journal of Ophthalmology 21(6): 685-90.
- Bronkhorst, I.H.G.; Maat, W.; Jordanova, E.S.; Kroes, W.G.M.; Schalij-Delfos, N.E.; Luyten, G.P.M. & Jager, M.J. (2011), Effect of Heterogeneous Distribution of Monosomy 3 on Prognosis in Uveal Melanoma, Archives of Pathology and Laboratory Medicine 135(8): 1042-1047.
- Bronkhorst, I.H.G.; Ly, L.V.; Jordanova, E.S.; Vrolijk, J.; Versluis, M.; Luyten, G.P.M. & Jager, M.J. (2011), Detection of M2-Macrophages in Uveal Melanoma and Relation with Survival, Investigative Ophthalmology & Visual Science 52(2): 643-650.
- Razzaq, L.; Emmanouilidis-van der Spek, K.; Luyten, G.P.M. & Keizer, R.J.W. de (2011), Anterior segment imaging for iris melanocytic tumors., European Journal of Ophthalmology.
- Ly, L.V.; Bronkhorst, I.H.G.; Beelen, E. van; Vrolijk, J.; Taylor, A.W.; Versluis, M.; Luyten, G.P.M. & Jager, M.J. (2010), Inflammatory Cytokines in Eyes with Uveal Melanoma and Relation with Macrophage Infiltration, Investigative Ophthalmology & Visual Science 51(11): 5445-5451.
- Ly, L.V.; Sluijter, M.; Versluis, M.; Luyten, G.P.M.; Burg, S.H. van der; Melief, C.J.M.; Jager, M.J. & Hall, T. van (2010), Peptide Vaccination after T-Cell Transfer Causes Massive Clonal Expansion, Tumor Eradication, and Manageable Cytokine Storm, Cancer Research 70(21): 8339-8346.
- Ly, L.V.; Baghat, A.; Versluis, M.; Jordanova, E.S.; Luyten, G.P.M.; Rooijen, N. van; Hall, T. van; Velden, P.A. van der & Jager, M.J. (2010), In Aged Mice, Outgrowth of Intraocular Melanoma Depends on Proangiogenic M2-Type Macrophages, Journal of Immunology 185(6): 3481-3488.
- Akdag, F.; Hafezi, F.; Heule-Dieleman, H.A.G.; Bosch, W.A. van den; Luyten, G.P.M.; Tanghe, H.L.J. & Paridaens, D. (2010), Orbital metastases of breast cancer, Ophthalmologe 107(8): 728-732.
- Ly, L.V.; Odish, O.F.F.; Wolff-Rouendaal, D. de; Missotten, G.S.O.A.; Luyten, G.P.M. & Jager, M.J. (2010), Intravascular Presence of Tumor Cells as Prognostic Parameter in Uveal Melanoma: A 35-Year Survey, Investigative Ophthalmology & Visual Science 51(2): 658-665.
- Filali, M. el; Missotten, G.S.O.A.; Maat, W.; Ly, L.V.; Luyten, G.P.M.; Velden, P.A. van der & Jager, M.J. (2010), Regulation of VEGF-A in uveal melanoma, Investigative Ophthalmology & Visual Science.
- Ly L.V., Bronkhorst I.H.G., Beelen E. van, Taylor A.W., Versluis M., Luyten G.P.M., Claas F.H.J. & Jager M.J. (2010), Significance of inflammatory cytokines in eyes with uveal melanoma and relation with the presence of macrophage subtypes, Investigative Ophthalmology & Visual Science.
- El Filali M, Missotten GS, Maat W, Ly LV, Luyten GP, Van der Velden P & Jager MJ (2009), Regulation of VEGF-A in uveal melanoma.
- Maat W, el Filali M, Dirks-Mulder A, Luyten GPM, Gruis NA, Desjardins L, Boender P, Jager MJ & van der Velden PA (2009), Episodic Src activation in uveal melanoma revealed by kinase activity profiling, British Journal of Cancer 101(2): 312-319.
- Maat W, van der Slik AR, Verhoeven DHJ, Alizadeh BZ, Ly LV, Verduijn W, Luyten GPM, Mulder A, van Hall T & Koning F (2009), Evidence for Natural Killer Cell-Mediated Protection from Metastasis Formation in Uveal Melanoma Patients, Investigative Ophthalmology & Visual Science 50(6): 2888-2895.
- Muller K, Nowak PJCM, Naus N, de Pan C, van Santen CA, Levendag P & Luyten GPM (2009), LACRIMAL GLAND RADIOSENSITIVITY IN UVEAL MELANOMA PATIENTS, International Journal of Radiation Oncology - Biology - Physics 74(2): 497-502.
- Dick HB, Budo C, Malecaze F, Guell JL, Marinho AAP, Nuijts RMMA, Luyten GPM, Menezo JL & Kohnen T (2009), Foldable Artiflex Phakic Intraocular Lens for the Correction of Myopia Two-Year Follow-up Results of a Prospective European Multicenter Study, Ophthalmology: Journal of The American Academy of Ophthalmology 116(4): 671-677.
- Mensink HW, Vaarwater J, Kilic E, Naus NC, Mooy N, Luyten G, Bruggenwirth HT, Paridaens D & de Klein A (2009), Chromosome 3 Intratumor Heterogeneity in Uveal Melanoma, Investigative Ophthalmology & Visual Science 50(2): 500-504.
- Filali MKE, Kilic E, Melis M, de Klein A, de Jong M & Luyten GPM (2008), Expression of the SST receptor 2 in uveal melanoma is not a prognostic marker, Graefe's Archive for Clinical and Experimental Ophthalmology 246(11).
- Kilic E, Bruggenwirth HT, Meier M, Naus NC, Beverloo HB, Meijerink JR, Luyten GP & de Klein A (2008), Increased expression of p73 Delta ex2 transcript in uveal melanoma with loss of chromosome 1p, Melanoma Research 18(3).
- Maat W, Beiboer SHW, Jager MJ, Luyten GPM, Gruis NA & van der Velden PA (2008), Epigenetic regulation identifies RASEF as a tumor-suppressor gene in uveal melanoma, Investigative Ophthalmology & Visual Science 49(4).
- Saxena R, Boekhoorn SS, Mulder PGH, Noordzij B, van Rij G & Luyten GPM (2008), Long-term follow-up of endothelial cell change after artisan phakic intraocular lens implantation, Ophthalmology: Journal of The American Academy of Ophthalmology 115(4).
- Kilic E, Stijnen T & Luyten GPM (2008), Preenucleation radiotherapy, uveal melanoma, and competing risks - In reply, Archives of Ophthalmology -New Series- 126(4).
- Maat W, Missotten GS, Luyten GPM & de Keizer RJW (2008), Retained intraocular foreign body masquerading as malignant melanoma of the iris, Graefe's Archive for Clinical and Experimental Ophthalmology 246(4).
- Maat W, Kilic E, Luyten GPM, De Klein A, Jager MJ, Gruis NA & Van der Velden PA (2008), Pyrophosphorolysis detects B-RAF mutations in primary uveal melanoma, Investigative Ophthalmology & Visual Science 49(1).
- van Gils W, Mensink HW, Kilic E, Vaarwater J, Verbiest MM, Paridaens D, Luyten GP, de Klein A & Bruggenwirth HT (2007), Expression of APITD1 is not related to copy number changes of chromosomal region 1p36 or the prognosis of uveal melanoma, Investigative Ophthalmology & Visual Science 48(11).
- Hes FJ, van der Luijt RB, Janssen ALW, Zewald RA, de Jong GJ, Lenders JW, Links TP, Luyten GPM, Sijmons RH, Eussen HJ, Halley DJJ, Lips CJM, Pearson PL, van den Ouweland AMW & Majoor-Krakauer DF (2007), Frequency of Von Hippel-Lindau germline mutations in classic and non-classic Von Hippel-Lindau disease identified by DNA sequencing, Southern blot analysis and multiplex ligation-dependent probe amplification, Clinical Genetics 72(2).
- Zuidervaart W & Luyten GPM (2005), A retrospective analysis of five intra-ocular lenses and the predictive value of six different intra-ocular lens power calculation formulas, Ophthalmologica 219(6).
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