Jan Bruijn
Hoogleraar Immunopathologie, in het bijzonder de nier
- Naam
- Prof.dr. J.A. Bruijn
- Telefoon
- +31 71 526 6587
- j.a.bruijn@lumc.nl
- ORCID iD
- 0000-0001-7592-250X
Professor Bruijn is hoogleraar immunopathologie, in het bijzonder die van de nier.
Meer informatie over Jan Bruijn
Pathologie
Mijn werkzaamheden omvatten drie taken: patiëntenzorg, onderwijs en wetenschappelijk onderzoek. In de patiëntenzorg werk ik als patholoog. De patholoog stelt diagnoses bij patiënten aan de hand van weefselonderzoek. Binnen dit vakgebied ben ik gespecialiseerd in nierziektes. Daarnaast geef ik onderwijs aan studenten Geneeskunde, Biomedische Wetenschappen en Medische Biologie te Leiden. In het wetenschappelijk onderzoek richt ik mij tot ziektes van het immuunsysteem ('immunopathologie') en binnen dit gebied vooral op nierziektes. In de nier onderzoeken wij het zeer complexe netwerk van moleculen die een rol spelen in de normale situatie, bij het ontstaan van ziektes en na transplantatie. Door toepassing van moderne technieken, zoals moleculaire biologie en computertechnologie gaat dit onderzoek momenteel sneller dan ooit. Wij hebben dan ook goede hoop dat wij door het onderzoek meer zullen gaan begrijpen van nierziektes, zodat patiënten in een vroeger stadium en beter behandeld zullen kunnen worden.
Wetenschappelijke carrière
- Promotie: "Polyclonal B-cell stimulation and extracellular matrix in experimental glomerulonephritis" (1988)
- Oratie: “Herkenning en Begrip” (1996)
Hoogleraar Immunopathologie, in het bijzonder de nier
- Faculteit Geneeskunde
- Divisie 4
- Pathologie
- Gerrits, T.; Brouwer, I.J.; Dijkstra, K.L.; Wolterbeek, R.; Bruijn, J.A.; Scharpfenecker, M. & Baelde, H.J. (2023), Endoglin is an important mediator in the final common pathway of chronic kidney disease to end-stage renal disease, International Journal of Molecular Sciences 24(1).
- Yong, Q.; Dijkstra, K.L.; Keur, C. van der; Bruijn, J.A.; Eikmans, M. & Baelde, H.J. (2023), MIF Increases sFLT1 Expression in Early Uncomplicated Pregnancy and Preeclampsia, International Journal of Molecular Sciences 24(12).
- Bos, E.M.J.; Rijnink, E.C.; Zandbergen, M.; Pool, J.D.N.D. de; Almekinders, M.M.; Berden, J.H.M.; Bijl, M.; Hagen, E.C.; Kolster-Bijdevaate, C.; Steup-Beekman, G.M.; Wolterbeek, R.; Bloemenkamp, K.W.M.; Baelde, H.J.; Bruijn, J.A.; Bajema, I.M. & Wilhelmus, S. (2022), Increased microchimerism in peripheral blood of women with systemic lupus erythematosus, Clinical and Experimental Rheumatology 40(11): 2153-2160.
- Bos, E.M.J.; Sangle, S.R.; Wilhelmus, S.; Wolterbeek, R.; Jordan, N.; D'Cruz, D.; Isenberg, D.; Cook, H.T.; Bruijn, J.A. & Bajema, I.M. (2022), Use of Glomerular CD68+ Cells as a Surrogate Marker for Endocapillary Hypercellularity in Lupus Nephritis, Kidney International Reports 7(4): 841-847.
- Khalil, R.; Boels, M.G.S.; Group, P.; Berg, B.M. van den; Bruijn, J.A.; Rabelink, T.J.; Hogendoorn, P.C.W. & Baelde, H.J. (2022), Mutations in the heparan sulfate backbone elongating enzymes EXT1 and EXT2 have no major effect on endothelial glycocalyx and the glomerular filtration barrier, Molecular Genetics and Genomics 297.
- Bolognesi, M.M.; Capitoli, G.; Galimberti, S.; Cattoretti, G.; Bajema, I.; Bruijn, J.A.; Cook, H.T.; Noel, L.H.; Pagni, F.; Ferrario, F.; Trejo, M.W. & L'Imperio, V. (2022), Dissecting the histological features of lupus nephritis highlights new common patterns of injury in class III/IV, Annals of the Rheumatic Diseases 81(12): 1704-1711.
- Aanhold, C.C.L. van; Dijkstra, K.L.; Bos, M.; Wolterbeek, R.; Berg, B.M. van den; Bruijn, J.A.; Bajema, I.M. & Baelde, H.J. (2021), Reduced glomerular endothelial thrombomodulin is associated with glomerular macrophage infiltration in diabetic nephropathy, The American Journal of Pathology 191(5): 829-837.
- Gerrits, T.; Zandbergen, M.; Wolterbeek, R.; Bruijn, J.A.; Baelde, H.J. & Scharpfenecker, M. (2020), Endoglin promotes myofibroblast differentiation and extracellular matrix production in diabetic nephropathy, International Journal of Molecular Sciences 21(20).
- Daalen, E.E. van; Trejo, M.A.C.W.; Goceroglu, A.; Ferrario, F.; Joh, K.; Noel, L.H.; Ogawa, Y.; Wilhelmus, S.; Ball, M.J.; Honsova, E.; Hruskova, Z.; Kain, R.; Kimura, T.; Kollar, M.; Kronbichler, A.; Lindhard, K.; Puechal, X.; Salvatore, S.; Szpirt, W.; Takizawa, H.; Tesar, V.; Berden, A.E.; Dekkers, O.M.; Hagen, E.C.; Oosting, J.; Rahmattulla, C.; Wolterbeek, R.; Bos, W.J.; Bruijn, J.A. & Bajema, I.M. (2020), Developments in the histopathological classification of ANCA-associated glomerulonephritis, Clinical Journal of the American Society of Nephrology 15(8): 1103-1111.
- Aanhold, C.C.L. van; Bus, P.; Zandbergen, M.; Bos, M.; Berbee, J.F.P.; Quint, K.D.; Bruijn, J.A. & Baelde, H.J. (2020), The vascular endothelial growth factor inhibitor soluble FLT-1 ameliorates atopic dermatitis in APOC1 transgenic mice, Journal of Investigative Dermatology 140(2): 491-+.
- Bellur, S.S.; Roberts, I.S.D.; Troyanov, S.; Royal, V.; Coppo, R.; Cook, H.T.; Cattran, D.; Terroba, Y.A.; Asunis, A.M.; Bajema, I.; Bertoni, E.; Bruijn, J.A.; Cannata-Ortiz, P.; Casartelli, D.; Palma, A.M. di; Ferrario, F.; Fortunato, M.; Furci, L.; Gakiopoulou, H.; Ljubanovic, D.G.; Giannakakis, K.; Goma, M.; Grone, H.J.; Gutierrez, E.; Haider, S.A.; Honsova, E.; Ioachim, E.; Karkoszka, H.; Kipgen, D.; Maldyk, J.; Mazzucco, G.; Orhan, D.; Ozluk, Y.; Pantzaki, A.; Perkowska-Ptasinska, A.; Riispere, Z.; Soderberg, M.P.; Steenbergen, E.; Stoppacciaro, A.; Feilitzen, B.S. von & Tardanico, R. (2019), Reproducibility of the Oxford classification of immunoglobulin A nephropathy, impact of biopsy scoring on treatment allocation and clinical relevance of disagreements: evidence from the VALidation of IGA study cohort, Nephrology Dialysis Transplantation 34(10): 1681-1690.
- Chua, J.S.; Zandbergen, M.; Wolterbeek, R.; Baelde, H.J.; Es, L.A. van; Fijter, J.W. de; Bruijn, J.A. & Bajema, I.M. (2019), Complement-mediated microangiopathy in IgA nephropathy and IgA vasculitis with nephritis, Modern Pathology 32(8): 1147-1157.
- Khalil, R.; Koop, K.; Kreutz, R.; Spaink, H.P.; Hogendoorn, P.C.W.; Bruijn, J.A. & Baelde, H.J. (2019), Increased dynamin expression precedes proteinuria in glomerular disease, Journal of Pathology 247(2): 177-185.
- Khalil, R.; Lalai, R.A.; Wiweger, M.I.; Avramut, C.M.; Koster, A.J.; Spaink, H.P.; Bruijn, J.A.; Hogendoorn, P.C.W. & Baelde, H.J. (2019), Glomerular permeability is not affected by heparan sulfate glycosaminoglycan deficiency in zebrafish embryos, American Journal of Physiology - Renal Physiology 317(5).
- Barbour, S.J.; Coppo, R.; Zhang, H.; Liu, Z.H.; Suzuki, Y.; Matsuzaki, K.; Katafuchi, R.; Er, L.; Espino-Hernandez, G.; Kim, S.J.; Reich, H.N.; Feehally, J.; Cattran, D.C.; Russo, M.L.; Troyanov, S.; Cook, H.T.; Roberts, I.; Tesar, V.; Maixnerova, D.; Lundberg, S.; Gesualdo, L.; Emma, F.; Fuiano, L.; Beltrame, G.; Rollino, C.; Amore, A.; Camilla, R.; Peruzzi, L.; Praga, M.; Feriozzi, S.; Polci, R.; Segoloni, G.; Colla, L.; Pani, A.; Piras, D.; Angioi, A.; Cancarini, G.; Ravera, S.; Durlik, M.; Moggia, E.; Ballarin, J.; Giulio, S. di; Pugliese, F.; Serriello, I.; Caliskan, Y.; Sever, M.; Kilicaslan, I.; Locatelli, F.; Vecchio, L. del; Wetzels, J.F.M.; Peters, H.; Berg, U.; Carvalho, F.; Ferreira, A.C.D.; Maggio, M.; Wiecek, A.; Ots-Rosenberg, M.; Magistroni, R.; Topaloglu, R.; Bilginer, Y.; D'Amico, M.; Stangou, M.; Giacchino, F.; Goumenos, D.; Kalliakmani, P.; Gerolymos, M.; Galesic, K.; Geddes, C.; Siamopoulos, K.; Balafa, O.; Galliani, M.; Stratta, P.; Quaglia, M.; Bergia, R.; Cravero, R.; Salvadori, M.; Cirami, L.; Fellstrorn, B.; Smerud, H.K.; Ferrario, F.; Stellato, T.; Egido, J.; Martin, C.; Floege, J.; Eitner, F.; Lupo, A.; Bernich, P.; Mene, R.; Morosetti, M.; Kooten, C. van; Rabelink, T.; Reinders, M.E.J.; Grinyo, J.M.B.; Cusinato, S.; Benozzi, L.; Savoldi, S.; Licata, C.; Mizerska-Wasiak, M.; Martina, G.; Messuerotti, A.; Canton, A. dal; Esposito, C.; Migotto, C.; Triolo, G.; Mariano, F.; Pozzi, C.; Boero, R.; Bellur, S.; Mazzucco, G.; Giannakakis, C.; Honsova, E.; Sundelin, B.; Palma, A.M. di; Ferrario, F.; Gutierrez, E.; Asunis, A.M.; Barratt, J.; Tardanico, R.; Perkowska-Ptasinska, A.; Terroba, J.A.; Fortunato, M.; Pantzaki, A.; Ozluk, Y.; Steenbergen, E.; Soderberg, M.; Riispere, Z.; Furci, L.; Orhan, D.; Kipgen, D.; Casartelli, D.; Ljubanovic, D.G.; Gakiopoulou, H.; Bertoni, E.; Ortiz, P.C.; Karkoszka, H.; Groene, H.J.; Stoppacciaro, A.; Bajema, I.; Bruijn, J.; Oliveras, X.F.; Maldyk, J.; Loachim, E.; Bavbek, N.; Cook, T.; Troyanov, S.; Alpers, C.; Amore, A.; Barratt, J.; Berthoux, F.; Bonsib, S.; Bruijn, J.; D'Agati, V.; D'Amico, G.; Emancipator, S.; Emmal, F.; Ferrario, F.; Fervenza, F.; Florquin, S.; Fogo, A.; Geddes, C.; Groene, H.; Haas, M.; Hill, P.; Hogg, R.; Hsu, S.; Hunley, T.; Hladunewich; Jennette, C.; Joh, K.; Julian, B.; Kawamura, T.; Lai, F.; Leung, C.; Li, L.; Li, P.; Liu, Z.; Massat, A.; Mackinnon, B.; Mezzano, S.; Schena, F.; Tomino, Y.; Walker, P.; Wang, H.; Weening, J.; Yoshikawa, N.; Zeng, C.H.; Shi, S.F.; Nogi, C.; Suzuki, H.; Koike, K.; Hirano, K.; Kawamura, T.; Yokoo, T.; Hanai, M.; Fukami, K.; Takahashi, K.; Yuzawa, Y.; Niwa, M.; Yasuda, Y.; Maruyama, S.; Ichikawa, D.; Suzuki, T.; Shirai, S.; Fukuda, A.; Fujimoto, S.; Trimarchi, H. & Int IgA Nephropathy Network (2019), Evaluating a New International Risk-Prediction Tool in IgA Nephropathy, JAMA Internal Medicine 179(7): 942-952.
- Fanouriakis, A.; Kostopoulou, M.; Alunno, A.; Aringer, M.; Bajema, I.; Boletis, J.N.; Cervera, R.; Doria, A.; Gordon, C.; Govoni, M.; Houssiau, F.; Jayne, D.; Kouloumas, M.; Kuhn, A.; Larsen, J.L.; Lerstrom, K.; Moroni, G.; Mosca, M.; Schneider, M.; Smolen, J.S.; Svenungsson, E.; Tesar, V.; Tincani, A.; Troldborg, A.; Vollenhoven, R. van; Wenzel, J.; Bertsias, G. & Boumpas, D.T. (2019), 2019 update of the EULAR recommendations for the management of systemic lupus erythematosus, Annals of the Rheumatic Diseases 78(6): 736-745.
- Trejo, M.A.C.W.; Flossmann, O.; Westman, K.W.; Hoglund, P.; Hagen, E.C.; Walsh, M.; Bruijn, J.A.; Jayne, D.R.W.; Bajema, I.M.; Berden, A.E. & European Vasculitis Soc (2019), Renal relapse in antineutrophil cytoplasmic autoantibody-associated vasculitis: unpredictable, but predictive of renal outcome, Rheumatology 58(1): 103-109.
- Rijnink, E.C.; Teng, Y.K.O.; Kraaij, T.; Dekkers, O.M.; Bruijn, J.A. & Bajema, I.M. (2018), Validation of the Systemic Lupus International Collaborating Clinics classification criteria in a cohort of patients with full house glomerular deposits, Kidney International 93(1): 214-220.
- Bus, P.; Chua, J.S.; Klessens, C.Q.F.; Zandbergen, M.; Wolterbeek, R.; Kooten, C. van; Trouw, L.A.; Bruijn, J.A. & Baelde, H.J. (2018), Complement Activation in Patients With Diabetic Nephropathy, Kidney International Reports 3(2): 302-313.
- Daalen, E.E. van; Jennette, J.C.; McAdoo, S.P.; Pusey, C.D.; Alba, M.A.; Poulton, C.J.; Wolterbeek, R.; Nguyen, T.Q.; Goldschmeding, R.; Alchi, B.; Griffiths, M.; Zoysa, J.R. de; Vincent, B.; Bruijn, J.A. & Bajema, I.M. (2018), Predicting Outcome in Patients with Anti-GBM Glomerulonephritis, Clinical Journal of the American Society of Nephrology 13(1): 63-72.
- Bajema, I.M.; Wilhelmus, S.; Alpers, C.E.; Bruijn, J.A.; Colvin, R.B.; Cook, H.T.; D'Agati, V.D.; Ferrario, F.; Haas, M.; Jennette, J.C.; Joh, K.; Nast, C.C.; Noel, L.H.; Rijnink, E.C.; Roberts, I.S.D.; Seshan, S.V.; Sethi, S. & Fogo, A.B. (2018), Revision of the International Society of Nephrology/Renal Pathology Society classification for lupus nephritis: clarification of definitions, and modified National Institutes of Health activity and chronicity indices, Kidney International 93(4): 789-796.
- Bus, P.; Gerrits, T.; Heemskerk, S.A.C.; Zandbergen, M.; Wolterbeek, R.; Bruijn, J.A.; Baelde, H.J. & Scharpfenecker, M. (2018), Endoglin Mediates Vascular Endothelial Growth Factor-A–Induced Endothelial Cell Activation by Regulating Akt Signaling, The American Journal of Pathology.
- Bus, P.; Scharpfenecker, M.; Wilk, P. van der; Wolterbeek, R.; Bruijn, J.A. & Baelde, H.J. (2017), The VEGF-A inhibitor sFLT-1 improves renal function by reducing endothelial activation and inflammation in a mouse model of type 1 diabetes, Diabetologia 60(9): 1813-1821.
- Elmonem, M.A.; Khalil, R.; Khodaparast, L.; Khodaparast, L.; Arcolino, F.O.; Morgan, J.; Pastore, A.; Tylzanowski, P.; Ny, A.; Lowe, M.; Witte, P.A. de; Baelde, H.J.; Heuvel, L.P. van den & Levtchenko, E. (2017), Cystinosis (ctns) zebrafish mutant shows pronephric glomerular and tubular dysfunction, Scientific Reports 7.
- Rijnink, E.C.; Teng, Y.K.O.; Wilhelmus, S.; Almekinders, M.; Wolterbeek, R.; Cransberg, K.; Bruijn, J.A. & Bajema, I.M. (2017), Clinical and Histopathologic Characteristics Associated with Renal Outcomes in Lupus Nephritis, Clinical Journal of the American Society of Nephrology 12(5): 734-743.
- Goceroglu, A.; Rahmattulla, C.; Berden, A.E.; Reinders, M.E.J.; Wolterbeek, R.; Steenbergen, E.J.; Hilbrands, L.B.; Noorlander, I.; Berger, S.P.; Peutz-Kootstra, C.J.; Christiaans, M.H.L.; Dijk, M.C.R.F. van; Joode, A.A.E. de; Goldschmeding, R.; Zuilen, A.D. van; Harper, L.; Little, M.A.; Hagen, E.C.; Bruijn, J.A. & Bajema, I.M. (2016), The Dutch Transplantation in Vasculitis (DUTRAVAS) Study: Outcome of Renal Transplantation in Antineutrophil Cytoplasmic Antibody-associated Glomerulonephritis, Transplantation 100(4): 916-924.
- Sethi, S.; Haas, M.; Markowitz, G.S.; D'Agati, V.D.; Rennke, H.G.; Jennette, J.C.; Bajema, I.M.; Alpers, C.E.; Chang, A.; Cornell, L.D.; Cosio, F.G.; Fogo, A.B.; Glassock, R.J.; Hariharan, S.; Kambham, N.; Lager, D.J.; Leung, N.; Mengel, M.; Nath, K.A.; Roberts, I.S.; Rovin, B.H.; Seshan, S.V.; Smith, R.J.H.; Walker, P.D.; Winearls, C.G.; Appel, G.B.; Alexander, M.P.; Cattran, D.C.; Casado, C.A.; Cook, H.T.; Vriese, A.S. de; Radhakrishnan, J.; Racusen, L.C.; Ronco, P. & Fervenza, F.C. (2016), Mayo Clinic/Renal Pathology Society Consensus Report on Pathologic Classification, Diagnosis, and Reporting of GN, Journal of the American Society of Nephrology 27(5): 1278-1287.
- Turner, R.J.; Bloemenkamp, K.W.M.; Bruijn, J.A. & Baelde, H.J. (2016), Loss of Thrombomodulin in Placental Dysfunction in Preeclampsia, Arteriosclerosis, Thrombosis, and Vascular Biology 36(4): 728-735.
- Bos, M.; Baelde, H.J.; Bruijn, J.A.; Bloemenkamp, K.W.M.; Hoorn, M.L.P. van der & Turner, R.J. (2016), Loss of Placental Thrombomodulin in Oocyte Donation Pregnancies., Fertility and Sterility 107.
- Wilhelmus, S.; Bajema, I.M.; Bertsias, G.K.; Boumpas, D.T.; Gordon, C.; Lightstone, L.; Tesar, V. & Jayne, D.R. (2016), Lupus nephritis management guidelines compared, Nephrology Dialysis Transplantation 31(6): 904-913.
- Rahmattulla, C.; Mooyaart, A.L.; Hooven, D. van; Schoones, J.W.; Bruijn, J.A.; Dekkers, O.M.; Bajema, I.M. & European Vasculitis Genetics (2016), Genetic variants in ANCA-associated vasculitis: a meta-analysis, Annals of the Rheumatic Diseases 75(9): 1687-1692.
- Yates, M.; Watts, R.A.; Bajema, I.M.; Cid, M.C.; Crestani, B.; Hauser, T.; Hellmich, B.; Holle, J.U.; Laudien, M.; Little, M.A.; Luqmani, R.A.; Mahr, A.; Merkel, P.A.; Mills, J.; Mooney, J.; Segelmark, M.; Tesar, V.; Westman, K.; Vaglio, A.; Yalcindag, N.; Jayne, D.R. & Mukhtyar, C. (2016), EULAR/ERA-EDTA recommendations for the management of ANCA-associated vasculitis, Annals of the Rheumatic Diseases 75(9): 1583-1594.
- Klessens, C.Q.F.; Woutman, T.D.; Veraar, K.A.M.; Zandbergen, M.; Valk, E.J.J.; Rotmans, J.I.; Wolterbeek, R.; Bruijn, J.A. & Bajema, I.M. (2016), An autopsy study suggests that diabetic nephropathy is underdiagnosed, Kidney International 90(1): 149-156.
- Rahmattulla, C.; Wijngaarden, R.A.F.L. van; Berden, A.E.; Hauer, H.A.; Flossmann, O.; Jayne, D.R.W.; Gaskin, G.; Rasmussen, N.; Noel, L.H.; Ferrario, F.; Waldherr, R.; Wolterbeek, R.; Goceroglu, A.; Pusey, C.D.; Hagen, E.C.; Bruijn, J.A.; Bajema, I.M. & European Vasculitis Study Grp EUVA (2015), Renal function and ear, nose, throat involvement in anti-neutrophil cytoplasmic antibody-associated vasculitis: prospective data from the European Vasculitis Society clinical trials, Rheumatology 54(5): 899-907.
- Tesar, V.; Troyanov, S.; Bellur, S.; Verhave, J.C.; Cook, H.T.; Feehally, J.; Roberts, I.S.D.; Cattran, D.; Coppo, R. & Valiga Study ERA-EDTA Immunonephro (2015), Corticosteroids in IgA Nephropathy: A Retrospective Analysis from the VALIGA Study, Journal of the American Society of Nephrology 26(9): 2248-2258.
- Chua, J.S.; Baelde, H.J.; Zandbergen, M.; Wilhelmus, S.; Es, L.A. van; Fijter, J.W. de; Bruijn, J.A.; Bajema, I.M. & Cohen, D. (2015), Complement Factor C4d Is a Common Denominator in Thrombotic Microangiopathy, Journal of the American Society of Nephrology 26(9): 2239-2247.
- Wilhelmus, S.; Cook, H.T.; Noel, L.H.; Ferrario, F.; Wolterbeek, R.; Bruijn, J.A. & Bajema, I.M. (2015), Interobserver Agreement on Histopathological Lesions in Class III or IV Lupus Nephritis, Clinical Journal of the American Society of Nephrology 10(1): 47-53.
- Penning, M.; Chua, J.S.; Kooten, C. van; Zandbergen, M.; Buurma, A.; Schutte, J.; Bruijn, J.A.; Khankin, E.V.; Bloemenkamp, K.; Karumanchi, S.A. & Baelde, H. (2015), Classical Complement Pathway Activation in the Kidneys of Women With Preeclampsia, Hypertension 66(1): 117-125.
- Wilhelmus, S.; Alpers, C.E.; Cook, H.T.; Ferrario, F.; Fogo, A.B.; Haas, M.; Joh, K.; Noel, L.H.; Seshan, S.V.; Bruijn, J.A. & Bajenna, I.M. (2015), The Revisited Classification of GN in SLE at 10 Years: Time to Re-Evaluate Histopathologic Lesions, Journal of the American Society of Nephrology 26(12): 2938-2946.
- Walsh, M.; Faurschou, M.; Berden, A.; Flossmann, O.; Bajema, I.; Hoglund, P.; Smith, R.; Szpirt, W.; Westman, K.; Pusey, C.D.; Jayne, D.R.W. & European Vasculitis Study Grp (2014), Long-Term Follow-Up of Cyclophosphamide Compared with Azathioprine for Initial Maintenance Therapy in ANCA-Associated Vasculitis, Clinical Journal of the American Society of Nephrology 9(9): 1571-1576.
- Mooyaart, A.L.; Valk, E.J.J.; Es, L.A. van; Bruijn, J.A.; Heer, E. de; Freedman, B.I.; Dekkers, O.M. & Baelde, H.J. (2014), Genetic associations in diabetic nephropathy: a meta-analysis (vol 54, pg 544, 2011), Diabetologia 57(3): 650-650.
- Kort, H. de; Mallat, M.J.K.; Kooten, C. van; Heer, E. de; Brand-Schaaf, S.H.; Wal, A.M. van der; Roufosse, C.; Roelen, D.L.; Bruijn, J.A.; Claas, F.H.; Fijter, J.W. de & Bajema, I.M. (2014), Diagnosis of Early Pancreas Graft Failure via Antibody-Mediated Rejection: Single-Center Experience With 256 Pancreas Transplantations, American Journal of Transplantation 14(4): 936-942.
- Penning, M.E.; Bloemenkamp, K.W.M.; Zon, T. van der; Zandbergen, M.; Schutte, J.M.; Bruijn, J.A.; Bajema, I.M. & Baelde, H.J. (2014), Association of Preeclampsia with Podocyte Turnover, Clinical Journal of the American Society of Nephrology 9(8): 1377-1385.
- Rahmattulla, C.; Bruijn, J.A. & Bajema, I.M. (2014), Histopathological classification of antineutrophil cytoplasmic antibody-associated glomerulonephritis: an update, Current Opinion in Nephrology and Hypertension 23(3): 224-231.
- Buurma, A.J.; Turner, R.J.; Driessen, J.H.M.; Mooyaart, A.L.; Schoones, J.W.; Bruijn, J.A.; Bloemenkamp, K.W.M.; Dekkers, O.M. & Baelde, H.J. (2013), Genetic variants in pre-eclampsia: a meta-analysis, Human Reproduction Update 19(3): 289-303.
- Buurma, A.J.; Penning, M.E.; Prins, F.; Schutte, J.M.; Bruijn, J.A.; Wilhelmus, S.; Rajakumar, A.; Bloemenkamp, K.W.M.; Karumanchi, S.A. & Baelde, H.J. (2013), Preeclampsia Is Associated With the Presence of Transcriptionally Active Placental Fragments in the Maternal Lung, Hypertension 62(3): 608-613.
- Berden, A.E.; Jones, R.B.; Erasmus, D.D.; Walsh, M.; Noel, L.H.; Ferrario, F.; Waldherr, R.; Bruijn, J.A.; Jayne, D.R.; Bajema, I.M. & European Vasculitis Soc (2012), Tubular Lesions Predict Renal Outcome in Antineutrophil Cytoplasmic Antibody-Associated Glomerulonephritis after Rituximab Therapy, Journal of the American Society of Nephrology 23(2): 313-321.
- Buurma, A.; Cohen, D.; Veraar, K.; Schonkeren, D.; Claas, F.H.; Bruijn, J.A.; Bloemenkamp, K.W. & Baelde, H.J. (2012), Preeclampsia Is Characterized by Placental Complement Dysregulation, Hypertension 60(5): 1332-+.
- Cohen, D.; Colvin, R.B.; Daha, M.R.; Drachenberg, C.B.; Haas, M.; Nickeleit, V.; Salmon, J.E.; Sis, B.; Zhao, M.H.; Bruijn, J.A. & Bajema, I.M. (2012), Pros and cons for C4d as a biomarker, Kidney International 81(7): 628-639.
- Walsh, M.; Flossmann, O.; Berden, A.; Westman, K.; Hoglund, P.; Stegeman, C.; Jayne, D. & European Vasculitis Study Grp (2012), Risk factors for relapse of antineutrophil cytoplasmic antibody-associated vasculitis, Arthritis and Rheumatism 64(2): 542-548.
- Berden, A.; Goceroglu, A.; Jayne, D.; Luqmani, R.; Rasmussen, N.; Bruijn, J.A. & Bajema, I. (2012), Diagnosis and management of ANCA associated vasculitis, British medical journal 344: -.
- Morgan, M.D.; Pachnio, A.; Begum, J.; Roberts, D.; Rasmussen, N.; Neil, D.A.H.; Bajema, I.; Savage, C.O.S.; Moss, P.A. & Harper, L. (2011), CD4+CD28-T Cell Expansion in Granulomatosis With Polyangiitis (Wegener's) Is Driven by Latent Cytomegalovirus Infection and Is Associated With an Increased Risk of Infection and Mortality, Arthritis and Rheumatism 63(7): 2127-2137.
- Heijl, C.; Harper, L.; Flossmann, O.; Stucker, I.; Scott, D.G.I.; Watts, R.A.; Hoglund, P.; Westman, K.; Mahr, A. & European Vasculitis Study Grp EUVA (2011), Incidence of malignancy in patients treated for antineutrophil cytoplasm antibody-associated vasculitis: follow-up data from European Vasculitis Study Group clinical trials, Annals of the Rheumatic Diseases 70(8): 1415-1421.
- Kort, H. de; Koning, E.J. de; Rabelink, T.J.; Bruijn, J.A. & Bajema, I.M. (2011), Islet transplantation in type 1 diabetes, British medical journal 342.
- Mooyaart, A.L.; Valk, E.J.J.; Es, L.A. van; Bruijn, J.A.; Heer, E. de; Freedman, B.I.; Dekkers, O.M. & Baelde, H.J. (2011), Genetic associations in diabetic nephropathy: a meta-analysis, Diabetologia 54(3): 544-553.
- Cohen, D.; Buurma, A.; Goemaere, N.N.; Girardi, G.; Cessie, S. le; Scherjon, S.; Bloemenkamp, K.W.M.; Heer, E. de; Bruijn, J.A. & Bajema, I.M. (2011), Classical complement activation as a footprint for murine and human antiphospholipid antibody-induced fetal loss, Journal of Pathology 225(4): 502-511.
- Valk, E.J.J.; Bruijn, J.A. & Bajema, I.M. (2011), Diabetic nephropathy in humans: pathologic diversity, Current Opinion in Nephrology and Hypertension 20(3): 285-289.
- Botermans, J.M.; Kort, H. de; Eikmans, M.; Koop, K.; Baelde, H.J.; Mallat, M.J.K.; Zuidwijk, K.; Kooten, C. van; Heer, E. de; Goemaere, N.N.T.; Claas, F.H.J.; Bruijn, J.A.; Fijter, J.W. de; Bajema, I.M. & Groningen, M.C. van (2011), C4d Staining In Renal Allograft Biopsies with Early Acute Rejection and Subsequent Clinical Outcome, Clinical Journal of the American Society of Nephrology 6(5): 1207-1213.
- Drachenberg, C.B.; Torrealba, J.R.; Nankivell, B.J.; Rangel, E.B.; Bajema, I.M.; Kim, D.U.; Arend, L.; Bracamonte, E.R.; Bromberg, J.S.; Bruijn, J.A.; Cantarovich, D.; Chapman, J.R.; Farris, A.B.; Gaber, L.; Goldberg, J.C.; Haririan, A.; Honsova, E.; Iskandar, S.S.; Klassen, D.K.; Kraus, E.; Lower, F.; Odorico, J.; Olson, J.L.; Mittalhenkle, A.; Munivenkatappa, R.; Paraskevas, S.; Papadimitriou, J.C.; Randhawa, P.; Reinholt, F.P.; Renaudin, K.; Revelo, P.; Ruiz, P.; Samaniego, M.D.; Shapiro, R.; Stratta, R.J.; Sutherland, D.E.R.; Troxell, M.L.; Voska, L.; Seshan, S.V.; Racusen, L.C. & Bartlett, S.T. (2011), Guidelines for the Diagnosis of Antibody-Mediated Rejection in Pancreas Allografts-Updated Banff Grading Schema, American Journal of Transplantation 11(9): 1792-1802.
- Cohen, D.; Berger, S.P.; Steup-Beekman, G.M.; Bloemenkamp, K.W.M. & Bajema, I.M. (2010), Diagnosis and management of the antiphospholipid syndrome., BMJ 340: c2541.
- Coppo, R.; Troyanov, S.; Camilla, R.; Hogg, R.J.; Cattran, D.C.; Cook, H.T.; Feehally, J.; Roberts, I.S.D.; Amore, A.; Alpers, C.E.; Barratt, J.; Berthoux, F.; Bonsib, S.; Bruijn, J.A.; D'Agati, V.; D'Amico, G.; Emancipator, S.N.; Emma, F.; Ferrario, F.; Fervenza, F.C.; Florquin, S.; Fogo, A.B.; Geddes, C.C.; Groene, H.J.; Haas, M.; Herzenberg, A.M.; Hill, P.A.; Hsu, S.I.; Jennette, J.C.; Joh, K.; Julian, B.A.; Kawamura, T.; Lai, F.M.; Li, L.S.; Li, P.K.; Liu, Z.H.; Mezzano, S.; Schena, F.P.; Tomino, Y.; Walker, P.D.; Wang, H.Y.; Weening, J.J.; Yoshikawa, N.; Zhang, H.; Int igA Nephropathy Network & Renal Pathology Soc (2010), The Oxford IgA nephropathy clinicopathological classification is valid for children as well as adults, Kidney International 77(10): 921-927.
- Tervaert, T.W.C.; Mooyaart, A.L.; Amann, K.; Cohen, A.H.; Cook, H.T.; Drachenberg, C.B.; Ferrario, F.; Fogo, A.B.; Haas, M.; Heer, E. de; Joh, K.; Noel, L.H.; Radhakrishnan, J.; Seshan, S.V.; Bajema, I.M.; Bruijn, J.A. & Renal Pathology Soc (2010), Pathologic Classification of Diabetic Nephropathy, Journal of the American Society of Nephrology 21(4): 556-563.
- Kort, H. de; Munivenkatappa, R.B.; Berger, S.P.; Eikmans, M.; Wal, A. van der; Koning, E.J. de; Kooten, C. van; Heer, E. de; Barth, R.N.; Bruijn, J.A.; Philosophe, B.; Drachenberg, C.B. & Bajema, I.M. (2010), Pancreas Allograft Biopsies with Positive C4d Staining and Anti-Donor Antibodies Related to Worse Outcome for Patients, American Journal of Transplantation 10(7): 1660-1667.
- Berden, A.E.; Ferrario, F.; Hagen, E.C.; Jayne, D.R.; Jennette, J.C.; Joh, K.; Neumann, I.; Noel, L.H.; Pusey, C.D.; Waldherr, R.; Bruijn, J.A. & Bajema, I.M. (2010), Histopathologic Classification of ANCA-Associated Glomerulonephritis, Journal of the American Society of Nephrology 21(10): 1628-1636.
- Mooyaart, A.L.; Zutinic, A.; Bakker, S.J.L.; Grootendorst, D.C.; Kleefstra, N.; Valkengoed, I.G.M. van; Bohringer, S.; Bilo, H.J.G.; Dekker, F.W.; Bruijn, J.A.; Navis, G.; Janssen, B.; Baelde, H.J. & Heer, E. de (2010), Association Between CNDP1 Genotype and Diabetic Nephropathy Is Sex Specific, Diabetes 59(6): 1555-1559.
- Cattran DC, Coppo R, Cook HT, Feehally J, Roberts ISD, Troyanov S, Alpers CE, Amore A, Barratt J, Berthoux F, Bonsib S, Bruijn JA, D'Agati V, D'Amico G, Emancipator S, Emma F, Ferrario F, Fervenza FC, Florquin S & Fogo A (2009), The Oxford classification of IgA nephropathy: rationale, clinicopathological correlations, and classification, Kidney International 76(5): 534-545.
- Roberts ISD, Cook HT, Troyanov S, Alpers CE, Amore A, Barratt J, Berthoux F, Bonsib S, Bruijn JA, Cattran DC, Coppo R, D'Agati V, D'Amico G, Emancipator S, Emma F, Feehally J, Ferrario F, Fervenza FC, Florquin S & Fogo A (2009), The Oxford classification of IgA nephropathy: pathology definitions, correlations, and reproducibility, Kidney International 76(5): 546-556.
- Daleboudt GMN, Bajema IM, Goemaere NNT, van Laar JM, Bruijn JA & Berger SP (2009), The clinical relevance of a repeat biopsy in lupus nephritis flares, Nephrology Dialysis Transplantation 24(12): 3712-3717.
- Mooyaart AL, van Valkengoed IGM, Shaw PKC, Peters V, Baelde HJ, Rabelink TJ, Bruijn JA, Stronks K & de Heer E (2009), Lower frequency of the 5/5 homozygous CNDP1 genotype in South Asian Surinamese, Diabetes Research and Clinical Practice 85(3): 272-278.
- Berden AE, Kallenberg CGM, Savage COS, Yard BA, Abdulahad WH, de Heer E, Bruijn JA & Bajema IM (2009), Cellular Immunity in Wegener's Granulomatosis, Arthritis and Rheumatism 60(6): 1578-1587.
- Hambach L, Ling KW, Pool J, Aghai Z, Blokland E, Tanke HJ, Bruijn JA, Halfwerk H, Van Boven H & Wieles B (2009), Hypomethylating drugs convert HA-1-negative solid tumors into targets for stem cell-based immunotherapy, Blood 113(12): 2715-2722.
- Ijpelaar DHT, Farris AB, Goemaere N, Amann K, Goldschmeding R, Nguyen TQ, Farkash E, van den Heuvel MC, de Heer E, Bruijn JA, Colvin RB & Bajema IM (2008), Fidelity and Evolution of Recurrent FSGS in Renal Allografts, Journal of the American Society of Nephrology 19(11).
- Cohen D, Koopmans M, Hovinga ICLK, Berger SP, van Groningen MR, Steup-Beekman GM, de Heer E, Bruijn JA & Bajema IM (2008), Potential for glomerular C4d as an indicator of thrombotic microangiopathy in lupus nephritis, Arthritis and Rheumatism 58(8).
- van Wijngaarden RAFDL, van Rijn L, Hagen EC, Watts RA, Gregorini G, Tervaert JWC, Mahr AD, Niles JL, de Heer E, Bruijn JA & Bajema IM (2008), Hypotheses on the etiology of antineutrophil cytoplasmic autoantibody-associated vasculitis: The cause is hidden, but the result is known, Clinical Journal of the American Society of Nephrology 3(1).
- Koopmans M, Hovinga ICLK, Baelde HJ, Harvey MS, de Heer E, Bruijn JA & Bajema IA (2008), Chimerism occurs in thyroid, lung, skin and lymph nodes of women with sons, Journal of Reproductive Immunology 78(1).
- IJpelaar DHT, Schulz A, Koop K, Schlesener M, Bruijn JA, Kerjaschki D, Kreutz R & de Heer E (2008), Glomerular hypertrophy precedes albuminuria and segmental loss of podoplanin in podocytes in Munich-Wistar-Fromter rats, AJP - Renal Physiology 294(4).
- Drachenberg CB, Odorico J, Demetris AJ, Arend L, Bajema IM, Bruijn JA, Cantarovich D, Cathro HP, Chapman J, Dimosthenous K, Fyfe-Kirschner B, Gaber L, Gaber O, Goldberg J, Honsova E, Iskandar SS, Klassen DK, Nankivell B, Papadimitriou JC, Racusen LC, Randhawa P, Reinholt FP, Renaudin K, Revelo PP, Ruiz P, Torrealba JR, Vazquez-Martul E, Voska L, Stratta R, Bartlett ST & Sutherland DER (2008), Banff schema for grading pancreas allograft rejection: Working proposal by a multi-disciplinary international consensus panel, American Journal of Transplantation 8(6).
- Eikmans M, Nacken W, Bajema IM, Zuidwijk K, Roos-van Groningen MC, van Kooten C, de Fijter JW, Bruijn JA, Roth J & Claas FHJ (2008), Presence of macrophage-expressed S100 calcium binding proteins AS and A9 during transplant rejection is associated with expression of IL-4, IL-10, and TGF-beta, Tissue Antigens 71(4).
- Hovinga ICLK, Koopmans M, Grootscholten C, van der Wal AM, Bijl M, Derksen RHWM, Voslcuyl AE, de Heer E, Bruijn JA, Berden JHM & Rajema IM (2008), Pregnancy, chimerism and lupus nephritis: a multi-centre study, Lupus 17(6).
- Koop K, Eikmans M, Wehland M, Baelde H, Ijpelaar D, Kreutz R, Kawachi H, Kerjaschki D, de Heer E & Bruijn JA (2008), Selective loss of podoplanin protein expression accompanies proteinuria and precedes alterations in podocyte morphology in a spontaneous proteinuric rat model, American Journal of Pathology 173(2).
- Cohen D, Koopmans M, Kremer Hovinga IC, Berger SP, Roos van Groningen M, Steup-Beekman GM, de Heer E, Bruijn JA & Bajema IM (2008), Potential for glomerular C4d as an indicator of thrombotic microangiopathy in lupus nephritis., Arthritis and Rheumatism 58(8): 2460-9.
- van Es LA, de Heer E, Vleming LJ, van der Wal A, Mallat M, Bajema I, Bruijn JA & de Fijter JW (2008), GMP-17-positive T-lymphocytes in renal tubules predict progression in early stages of IgA nephropathy, Kidney International 73(12).
- Hovinga ICLK, Koopmans M, Baelde HJ, de Heer E, Bruijn JA & Bajema IM (2007), Tissue chimerism in systemic lupus erythematosus is related to injury, Annals of the Rheumatic Diseases 66(12).
- Hovinga ICLK, Koopmans M, de Heer E, Bruijn JA & Bajema IM (2007), Chimerism in systemic lupus erythematosus - three hypotheses, Rheumatology 46(2).
- Plaisier I, de Bruijn JGM, de Graaf R, ten Have M, Beekman ATF & Penninx BWJH (2007), The contribution of working conditions and social support to the onset of depressive and anxiety disorders among male and female employees, Social Science and Medicine 64(2).
- Hovinga ICLK, Koopmans M, de Heer E, Bruijn JA & Bajema IM (2007), Change in blood group in systemic lupus erythematosus, Lancet 369(9557).
- de Lind VWRAF, Hauer HA, Flossmann O, Jayne DRW, Westman KW, Gaskin G, Rasmussen N, Noel LH, Ferrarici F, Waldherr R, Hagen EC, Bruijn JA & Bajema IM (2007), Clinical and histological determinants of long-term outcome in ANCA-associated glomerulonephritis, Clinical and Experimental Rheumatology 25(1).
- Lupetti A, Brouwer CPJM, Bogaards SJP, Welling MM, de Heer E, Campa M, van Dissel JT, Friesen RHE & Nibbering PH (2007), Human lactoferrin-derived peptide's antifungal activities against disseminated Candida albicans infection, Journal of Infectious Diseases 196(9).
- de Lind van Wijngaarden RAF, Hauer HA, Jayne DRW, Gaskin G, Rasmussen N, Noi LH, Ferrario F, Waldherr R, Hagen EC, Bruijn JA & Bajema IM (2007), Translation of renal histology into clinical severity of ANCA-associated vasculitis, Clinical and Experimental Rheumatology 25(1).
- Baelde HJ, Eikmans M, Lappin DWP, Doran PP, Hohenadel D, Brinkkoetter PT, van der Woude FJ, Waldherr R, Rabelink TJ, de Heer E & Bruijin JA (2007), Reduction of VEGF-A and CTGF expression in diabetic nephropathy is associated with podocyte loss, Kidney International 71(7).
- van Wijngaarden RAFDL, Hauer HA, Wolterbeek R, Jayne DRW, Gaskin G, Rasmussen N, Noel LH, Ferrario F, Waldherr R, Bruijn JA, Bajema IM & Hagen EC (2007), Chances of renal recovery for dialysis-dependent ANCA-associated glomerulonephritis, Journal of the American Society of Nephrology 18(7).
- Koopmans M, Hovinga ICLK, Baelde HJ, de Heer E, Bruijn JA & Bajema IM (2006), Endothelial chimerism in transplantation: Looking for needles in a haystack, Transplantation 82(1).
- Van Wijngaarden RAFD, Hauer HA, Wolterbeek R, Jayne DRW, Gaskin G, Rasmussen N, Noel LH, Ferrario F, Waldherr R, Hagen EC, Bruijn JA & Bajema IM (2006), Clinical and histologic determinants of renal outcome in ANCA-associated vasculitis: A prospective analysis of 100 patients with severe renal involvement, Journal of the American Society of Nephrology 17(8).
- Pinkse GGM, Bouwman WP, Jiawan-Lalai R, Terpstra OT, Bruijn JA & de Heer E (2006), Integrin signaling via RGD peptides and anti-beta 1 antibodies confers resistance to apoptosis in islets of Langerhans, Diabetes 55(2).
- Grootscholten C, Ligtenberg G, Hagen EC, Bake AWLVW, de Glas-Vos JW, Bijl M, Assmann KJ, Bruijn JA, Weening JJ, van Houwelingen HC, Derksen RHWM & Berden JHM (2006), Azathioprine/methylprednisolone versus cyclophosphamide in proliferative lupus nephritis. A randomized controlled trial, Kidney International 70(4).
- Aben JA, Ijpelaar DH, Baelde H, Worley P, Noble N, Bruijn JA & de Heer E (2006), Glomerular expression of neuronal activity-regulated pentraxin precedes the development of anti-Thy-1-induced progressive glomerulosclerosis, Kidney International 70(7).
- Groningen MCRV, Scholten EM, Lelieveld PM, Rowshani AT, Baelde HJ, Bajema IM, Florquin S, Bemelman FJ, de Heer E, de Fijter JW, Bruijn JA & Eikmans M (2006), Molecular comparison of calcineurin inhibitor-induced fibrogenic responses in protocol renal transplant biopsies, Journal of the American Society of Nephrology 17(3).
- Hovinga ICLK, Koopmans M, Baelde HJ, van der Wal AA, Sijpkens YWJ, de Heer E, Bruijn JA & Bajema IA (2006), Chimerism occurs twice as often in lupus nephritis as in normal kidneys, Arthritis and Rheumatism 54(9).
- Koopmans M, Hovinga ICLK, Baelde HJ, Fernandes RJ, de Heer E, Bruijn JA & Bajema IM (2005), Chimerism in kidneys, livers and hearts of normal women: Implications for transplantation studies, American Journal of Transplantation 5(6).
- Pinkse GGM, Jiawan-Lalai R, Bruijn JA & de Heer E (2005), RGD peptides confer survival to hepatocytes via the beta 1-integrin-ILK-pAkt pathway, Journal of Hepatology 42(1).
- Eikmans M, Baelde HJ, de Heer E & Bruijn JA (2005), Messenger RNA assessment in clinical nephrology: perspectives and progress of methodology, Nephrology Dialysis Transplantation 20(12).
- Eikmans M, Roos-van Groningen MC, Sijpkens YWJ, Ehrchen J, Roth J, Baelde HJ, Bajema IM, de Fijter JW, de Heer E & Bruijn JA (2005), Expression of surfactant protein-C, S100A8, S100A9, and B cell markers in renal allografts: Investigation of the prognostic value, Journal of the American Society of Nephrology 16(12).
- van Poelgeest EP, Baelde HJ, Lagaaij EL, Sijpkens YWJ, de Heer E, Bruijn JA & Bajema IM (2005), Endothelial cell chimerism occurs more often and earlier in female than in male recipients of kidney transplants, Kidney International 68(2).
- Roos-van Groningen MC, Eikmans M, Baelde HJ, de Heer E & Bruijn JA (2004), Improvement of extraction and processing of RNA from renal biopsies, Kidney International 65(1).
- Boom H, Mallat MJK, De Fijter JW, Paul LC, Bruijn JA & Van Es LA (2004), Calcium levels as a risk factor for delayed graft function, Transplantation 77(6).
- D'Agati VD, Fogo AB, Bruijn JA & Jennette JC (2004), Pathologic classification of focal segmental glomerulosclerosis: A working proposal, American Journal of Kidney Diseases 43(2).
- Baelde HJ, Eikmans M, Doran PP, Lappin DWP, de Heer E & Bruijn JA (2004), Gene expression profiling in glomeruli from human kidneys with diabetic nephropathy, American Journal of Kidney Diseases 43(4).
- Pinkse GGM, Steenvoorde E, Hogendoorn S, Noteborn M, Terpstra OT, Bruijn JA & de Heer E (2004), Stable transplantation results of magnetically retracted islets: a novel method, Diabetologia 47(1).
- Weening JJ, D'Agati VD, Schwartz MM, Seshan SV, Alpers CE, Appel GB, Balow JE, Bruijn JA, Cook T, Ferrario F, Fogo AB, Ginzler EM, Hebert L, Hill G, Hill P, Jennette JC, Kong NC, Lesavre P, Lockshin M, Looi LM, Makino H, Moura LA & Nagata M (2004), The classification of glomerulonephritis in systemic lupus erythematosus revisited, Kidney International 65(2).
- Siegel AK, Kossmehl P, Planert M, Schulz A, Wehland M, Stoll M, Bruijn JA, de Heer E & Kreutz R (2004), Genetic linkage of albuminuria and renal injury in Dahl salt-sensitive rats on a high-salt diet: comparison with spontaneously hypertensive rats, Physiological Genomics 18(2).
- Sijpkens YW, Joosten SA, Wong MC, Dekker FW, Benediktsson H, Bajema IM, Bruijn JA & Paul LC (2004), Immunologic risk factors and glomerular C4d deposits in chronic transplant glomerulopathy, Kidney International 65(6).
- Weening JJ, D'Agati VD, Schwartz MM, Seshan SV, Alpers CE, Appel GB, Balow JE, Bruijn JA, Cook T, Ferrario F, Fogo AB, Ginzler EM, Hebert L, Hill G, Hill P, Jennette JC, Kong NC, Lesavre P, Lockshin M, Looi LM, Makino H, Moura LA & Nagata M (2004), The classification of glomerulonephritis in systemic lupus erythematosus revisited, Journal of the American Society of Nephrology 15(2).
- Eikmans M, IJpelaar DHT, Baelde HJ, de Heer E & Bruijn JA (2004), The use of extracellular matrix probes and extracellular matrix-related probes for assessing diagnosis and prognosis in renal diseases, Current Opinion in Nephrology and Hypertension 13(6).
- Pinkse GGM, Voorhoeve MP, Noteborn M, Terpstra OT, Bruijn JA & de Heer E (2004), Hepatocyte survival depends on beta 1-integrin-mediated attachment of hepatocytes to hepatic extracellular matrix, Liver International 24(3).
- Koop K, Bakker RC, Eikmans M, Baelde HJ, de Heer E, Paul LC & Bruijn JA (2004), Differentiation between chronic rejection and chronic cyclosporine toxicity by analysis of renal cortical mRNA, Kidney International 66(5).
- Baelde HJ, Eikmans M, van Vliet AI, Bergijk EC, de Heer E & Bruijn JA (2004), Alternatively spliced isoforms of fibronectin in immune-mediated glomerulosclerosis: the role of TGF beta and IL-4, Journal of Pathology 204(3).
- Jonkers IJ, Bruijn JA & Vleming LJ (2004), A case of minimal change disease evolving into steroid-dependent nephrotic syndrome with hematuria, American Journal of Kidney Diseases 44(4).
- Aydin Z, Bruijn JA & Vleming LJ (2004), ARF and cerebral infarcts in a young woman, American Journal of Kidney Diseases 44(1).
- Vergunst CE, van Gurp E, Hagen C, van Houwelingen HC, Hauer HA, Noel LH, Waldherr R, Ferrario F, van der Woude FJ, Bruijn JA & Bajema IM (2003), An index for renal outcome in ANCA-associated glomerulonephritis, American Journal of Kidney Diseases 41(3).
- Sijpkens YWJ, Doxiadis IIN, van Kemenade FJ, Zwinderman AH, de Fijter JW, Claas FHJ, Bruijn JA & Paul LC (2003), Chronic rejection with or without transplant vasculopathy, Clinical Transplantation 17(3).
- Volkers AC, Tulen JHM, van den Broek WW, Bruijn JA, Passchier J & Pepplinkhuizen L (2003), Motor activity and autonomic cardiac functioning in major depressive disorder, Journal of Affective Disorders 76(1-3).
- Hauer HA, Hagen EC, de Heer E, Bruijn JA & Bajema IM (2003), Glomerulonephritis in the vasculitides: advances in immunopathology, Current Opinion in Rheumatology 15(1).
- Sijpkens YWJ, Doxiadis IIN, Mallat MJK, De Fijter JW, Bruijn JA, Claas FHJ & Paul LC (2003), Early versus late acute rejection episodes in renal transplantation, Transplantation 75(2).
- Bakker RC, Hollander AAMJ, Mallat MJK, Bruijn JA, Paul LC & de Fijter JW (2003), Conversion from cyclosporine to azathioprine at three months reduces the incidence of chronic allograft nephropathy, Kidney International 64(3).
- Eikmans M, Baelde JJ, de Heer E & Bruijn JA (2003), ECM homeostasis in renal diseases: a genomic approach, Journal of Pathology 200(4).
- Bakker RC, Koop K, Sijpkens YW, Eikmans M, Bajema IM, De Heer E, Bruijn JA & Paul LC (2003), Early interstitial accumulation of collagen type I discriminates chronic rejection from chronic cyclosporine nephrotoxicity, Journal of the American Society of Nephrology 14(8).
- van den Broek WW, Groenland THN, Kusuma A, Mulder PGH & Bruijn JA (2003), Alfentanil has no proconvulsive effect during electroconvulsive therapy, Canadian Journal of Anesthesia / Journal canadien d'anesth�sie 50(2).
- Eikmans M, Baelde HJ, Hagen EC, Paul LC, Eilers PHC, De Heer E & Bruijn JA (2003), Renal mRNA levels as prognostic tools in kidney diseases, Journal of the American Society of Nephrology 14(4).
- Aben JA, Hoogervorst DA, Paul LC, Borrias MC, Noble NA, Border WA, Bruijn JA & De Heer E (2003), Genes expressed by the kidney, but not by bone marrow-derived cells, underlie the genetic predisposition to progressive glomerulosclerosis after mesangial injury, Journal of the American Society of Nephrology 14(9).
- Mehr AP, Siegel AK, Kossmehl P, Schulz A, Plehm R, de Bruijn JA, de Heer E & Kreutz R (2003), Early onset albuminuria in Dahl rats is a polygenetic trait that is independent from salt loading, Physiological Genomics 14(3).
- Leussink BT, Baelde HJ, Broekhuizen-van den Berg TM, de Heer E, van der Voet GB, Slikkerveer A, Bruijn JA & de Wolff FA (2003), Renal epithelial gene expression profile and bismuth-induced resistance against cisplatin nephrotoxicity, Human and Experimental Toxicology 22(10).
- Koop K, Eikmans M, Baelde HJ, Kawachi H, De Heer E, Paul LC & Bruijn JA (2003), Expression of podocyte-associated molecules in acquired human kidney diseases, Journal of the American Society of Nephrology 14(8).
- Havenga MJE, Lemckert AAC, Ophorst OJAE, van Meijer M, Germeraad WTV, Grimbergen J, van den Doel MA, Vogels R, van Deutekom J, Janson AAM, de Bruijn JD, Uytdehaag F, Quax PHA, Logtenberg T, Mehtali M & Bout A (2002), Exploiting the natural diversity in adenovirus tropism for therapy and prevention of disease, Journal of Virology 76(9).
- Eikmans M, Baelde HJ, Hagen CE, Paul LC, Eilers PHC, de Heer E & Bruijn JA (2002), Renal mRNA levels as prognostic tools in kidney diseases., Journal of the American Society of Nephrology 13.
- Eikmans M, Sijpkens YWJ, Baelde HJ, De Heer E, Paul LC & Bruijn JA (2002), High transforming growth factor-beta and extracellular matrix mRNA response in renal allografts during early acute rejection is associated with absence of chronic rejection, Transplantation 73(4).
- Bruijn JA & van der Woude FJ (2002), Tacrollmus and ciclosporin microemulsion in renal transplantation, Lancet 360(9335).
- Eikmans M, Baelde HJ, De Heer E & Bruijn JA (2002), RNA expression profiling as prognostic tool in renal patients: Toward nephrogenomics, Kidney International 62(4).
- Hauer HA, Bajema IM, van Houwelingen HC, Ferrario F, Noel LH, Waldherr R, Jayne DRW, Rasmussen N, Bruijn JA & Hagen EC (2002), Renal histology in ANCA-associated vasculitis: Differences between diagnostic and serologic subgroups, Kidney International 61(1).
- van Vliet AI, van Alderwegen IE, Baelde HJ, de Heer E & Bruijn JA (2002), Fibronectin accumulation in glomerulosclerotic lesions: Self-assembly sites and the heparin II binding domain, Kidney International 61(2).
- Koolbergen, D.R.; Hazekamp, M.G.; Heer, E. de; Hoorn, F. van; Huysmans, H.A.; Bruijn, J.A. & Dion, R.A.E. (2002), Structural degeneration of pulmonary homografts used as aortic valve substitute underlines early graft failure, European Journal of Cardio-Thoracic Surgery 22(5).
- Leussink BT, Nagelkerke JF, van de Water B, Slikkerveer A, van der Voet GB, Srinivasan A, Bruijn JA, de Wolff FA & de Heer E (2002), Pathways of proximal tubular cell death in bismuth nephrotoxicity, Toxicology and Applied Pharmacology 180(2).
- Xu W, Baelde HJ, Lagaaij EL, De Heer E, Paul LC & Bruijn JA (2002), Endothelial cell chimerism after renal transplantation in a rat model, Transplantation 74(9).
- Koolbergen, D.R.; Hazelkamp, M.G.; Heer, E. de; Bruggemans, E.F.; Huysmans, H.A.; Dion, R.A.E. & Bruijn, J.A. (2002), The pathology of fresh and cryopreserved homograft heart valves: An analysis of forty explanted homograft valves, The Journal of Thoracic and Cardiovascular Surgery 124(4).
- Hauer HA, Bajema IM, Hagen EC, Noel LH, Ferrario F, Waldherr R, van Houwelingen HC, Lesavre P, Sinico RA, van der Woude F, Gaskin G, Verburgh CA, de Heer E & Bruijn JA (2002), Long-term renal injury in ANCA-associated vasculitis: an analysis of 31 patients with follow-up biopsies, Nephrology Dialysis Transplantation 17(4).
- Hauer HA, Bajema IM, Van Houwelingen HC, Ferrario F, Noel LH, Waldherr R, Jayne DRW, Rasmussen N, Bruijn JA & Hagen EC (2002), Determinants of outcome in ANCA-associated glomerulonephritis: A prospective clinico-histopathological analysis of 96 patients, Kidney International 62(5).
- Sijpkens YWJ, Bruijn JA & Paul LC (2001), Chronic allograft nephropathy categorised in chronic interstitial and vascular rejection, Transplantation Proceedings 33(1-2).
- Leussink BT, Litvinov SV, de Heer E, Slikkerveer A, van der Voet GB, Bruijn JA & de Wolff FA (2001), Loss of homotypic epithelial cell adhesion by selective N-cadherin displacement in bismuth nephrotoxicity, Toxicology and Applied Pharmacology 175(1).
- Eikmans M, Baelde HJ, de Heer E & Bruijn JA (2001), Effect of age and biopsy site on extracellular matrix mRNA and protein levels in human kidney biopsies, Kidney International 60(3).
- Van Vliet AI, Baelde HJ, Vleming LJ, de Heer E & Bruijn JA (2001), Distribution of fibronectin isoforms in human renal disease, Journal of Pathology 193(2).
- Leussink BT, Slikkerveer A, Engelbrecht MRW, van der Voet GB, Nouwen EJ, de Heer E, de Broe ME, de Wolff FA & Bruijn JA (2001), Bismuth overdosing-induced reversible nephropathy in rats, Archives of Toxicology 74(12).
- Bajema IM, Hagen EC, Ferrario F, de Heer E & Bruijn JA (2001), Immunopathological aspects of systemic vasculitis, Springer Seminars in Immunopathology 23(3).
- Bruijn JA, Verburgh CA & Huizinga TWJ (2001), Classifying lupus nephritis: A 32-year-old woman with systemic lupus erythematosus and nephritic syndrome, American Journal of Kidney Diseases 37(3).
- Lagaaij EL, Cramer-Knijnenburg GF, van Kemenade FJ, van Es LA, Bruijn JA & van Krieken JHJM (2001), Endothelial cell chimerism after renal transplantation and vascular rejection, Lancet 357(9249).
- Peutz-Kootstra CJ, De Heer E, Hoedemaeker J, Abrass CK & Bruijn JA (2001), Lupus nephritis: Lessons from experimental animal models, Journal of Laboratory and Clinical Medicine 137(4).
- Lagaaij EL, van Kemenade F, van Es B, Bruijn JA & van Krieken H (2001), Circulating endothelial cells after transplantation - Reply, Lancet 357(9266).
- Bajema IM, Hagen EC, de Heer E, van der Woude J & Bruijn JA (2001), Colocalization of ANCA-antigens and fibrinoid necrosis in ANCA-associated vasculitis, Kidney International 60(5).
- Eikmans M, Baelde HJ, De Heer E & Bruijn JA (2000), Processing renal biopsies for diagnostic mRNA quantification: Improvement of RNA extraction and storage conditions.
- Hauer HA, Bajema IM, de Heer E, Hermans J, Hagen EC & Bruijn JA (2000), Distribution of renal lesions in idiopathic systemic vasculitis: A three-dimensional analysis of 87 glomeruli, American Journal of Kidney Diseases 36(2).
- Schoof PH, Gittenberger-de Groot AC, de Heer E, Bruijn JA, Hazekamp MG & Huysmans HA (2000), Remodeling of the porcine pulmonary autograft wall in the aortic position.
- de Jong-Tieben LM, Berkhout RJM, ter Schegget J, Vermeer BJ, de Fijter JW, Bruijn JA, Westendorp RGJ & Bavinck JNB (2000), The prevalence of human papillomavirus DNA in benign keratotic skin lesions of renal transplant recipients with and without a history of skin cancer is equally high: A clinical study to assess risk factors for keratotic skin lesions and skin cancer.
- Valentin JF, Bruijn JA & Paul LC (2000), Donor treatment with mycophenolate mofetil - Protection against ischemia-reperfusion injury in the rat.
- De Heer E, Sijpkens YWJ, Verkade M, den Dulk M, Langers A, Schutrups J, Bruijn JA & van Es LA (2000), Morphometry of interstitial fibrosis, Nephrology Dialysis Transplantation 15.
- Luca ME, Paul LC, van der Wal AM, Bruijn JA & de Heer E (2000), Treatment with mycophenolate mofetil attenuates the development of Heymann nephritis.
- Peutz-Kootstra CJ, Hansen K, De Heer E, Abrass CK & Bruijn JA (2000), Differential expression of laminin chains and anti-laminin autoantibodies in experimental lupus nephritis, Journal of Pathology 192(3).
- Bajema IM & Bruijn JA (2000), What stuff is this! A historical perspective on fibrinoid necrosis.
- Van Riemsdijk IC, Mulder PG, De Fijter JW, Bruijn JA, Van Hooff JP, Hoitsma AJ, Tegzess AM & Weimar W (2000), Addition of isradipine (Lomir) results in a better renal function after kidney transplantation: A double-blind, randomized, placebo-controlled, multicenter study.
- Leussink BT, Slikkerveer A, Krauwinkel WJJ, van der Voet GB, de Heer E, de Wolff FA & Bruijn JA (2000), Bismuth biokinetics and kidney histopathology after bismuth overdose in rats, Archives of Toxicology 74(7).
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