Eline Slagboom
Hoogleraar Moleculaire Epidemiologie
- Naam
- Prof.dr. P. Slagboom
- Telefoon
- +31 71 526 9731
- p.slagboom@lumc.nl
- ORCID iD
- 0000-0002-2875-4723
P. Eline Slagboom is professor in de moleculaire epidemiologie en hoofd van de gelijknamige sectie in de afdeling ‘Biomedical Data Sciences’. Ze is voorzitter van het LUMC Profilerings gebied ‘Ageing’ en van de Vereniging voor Verouderingsonderzoek. Slagboom is de ‘principle investigator’ van de Leiden LangLeven Studie en ze is Fellow bij het Max Planck Instituut voor de Biologie van Veroudering in Keulen, Duitsland en bestuurslid van het biobanken consortium BBMRI-NL (Biobanking and Biomolecular Resources Research Infrastructure) waar zij het nationale metabolomics onderzoek leidt. Slagboom zit in het organiserend committee van prestigieuze congressen zoals die van de Welcome Trust, UK).
Meer informatie over Eline Slagboom
P. Eline Slagboom is professor in de moleculaire epidemiologie en hoofd van de gelijknamige sectie in de afdeling ‘Biomedical Data Sciences’. Ze is voorzitter van het LUMC Profilerings gebied ‘Ageing’ en van de Vereniging voor Verouderingsonderzoek. Slagboom is de ‘principle investigator’ van de Leiden LangLeven Studie en ze is Fellow bij het Max Planck Instituut voor de Biologie van Veroudering in Keulen, Duitsland en bestuurslid van het biobanken consortium BBMRI-NL (Biobanking and Biomolecular Resources Research Infrastructure) waar zij het nationale metabolomics onderzoek leidt. Slagboom zit in het organiserend committee van prestigieuze congressen zoals die van de Welcome Trust, UK).
Moleculaire Epidemiologie
In de afgelopen 25 jaar ben ik geinspireerd geweest door het feit dat het verouderingsproces de basis vormt van de meest frequente ziekten, tussen mensen zeer verschillend verloopt en modificeerbaar is. De studies in mijn groep naar de moleculaire epidemiologie van veroudering omvatten studies naar de biologie van het genoom, naar de aetiologie en biomarkers van verouderingsziekten en van langlevendheid en gezond ouder worden. Mijn leerstoel en ons werk houden verband met diverse NWA agendas (Big data, preventie en gezondheid en precisie geneeskunde) en resulteerde in meer dan 400 publicaties en het slagen van meer dan 20 jonge promovendi. Recentelijk bestuderen we ook de respons van ouderen op leefstijl interventies (de Samen Oud Samen Thuis Studie).
Ik geef met passie les en heb een MOOC en trainingsprogramma ontwikkeld om creatief en logisch denken in de wetenschap te stimuleren bij middelbare school leerlingen en hun leraren. Deze training geef ik ook aan studenten in de LUMC Master Vitality and Ageing.
Wetenschappelijke carrière
Professor P. Eline Slagboom rondde de studie biologie af in 1985 in Leiden en promoveerde op 30-11-1993 op haar proefschrift getiteld ‘Genomic instability and aging”. Tussen ’93 en 2000 was zij groepsleider bij het TNO Gaubius Instituut en werd in 2000 benoemd tot hoogleraar in de Moleculaire Epidemiologie bij het Leids Universitair Medisch Centrum. Haar inauguratie vond plaats op 21-03-2003 en de oratie was getiteld: ‘Van het concert des levens…’
Slagboom trok veel getalenteerde onderzoekers aan en haar groep groeide aanzienlijk over de jaren door verworven subsidies en samenwerking met de industrie. De grootste projecten die zij coördineerde betroffen een door NWO gesteund grootschalig genotypeer-centrum, een grootschalig FP-7 EU project (IDEAL: Integrated research on DEvelopmental determinants of Aging and Longevity) en het Netherlands Consortium for Healthy Ageing.
Prijzen en eervolle benoemingen
- Designers and Artists 4 Genomics Award (2011).
- Benoemd als Fellow bij het Max Planck Instituut voor de Biologie van Veroudering in Keulen, Duitsland
Hoogleraar Moleculaire Epidemiologie
- Faculteit Geneeskunde
- Divisie 4
- Biomedical Data Sciences
- Moleculaire Epidemiologie
- Moqri, M.; Herzog, C.; Poganik, J.R.; Ying, K.J.; Justice, J.N.; Belsky, D.W.; Higgins-Chen, A.T.; Chen, B.H.; Cohen, A.A.; Fuellen, G.; Haegg, S.; Marioni, R.E.; Widschwendter, M.; Fortney, K.; Fedichev, P.O.; Zhavoronkov, A.; Barzilai, N.; Lasky-Su, J.; Kiel, D.P.; Kennedy, B.K.; Cummings, S.; Slagboom, P.E.; Verdin, E.; Maier, A.B.; Sebastiano, V.; Snyder, M.P.; Gladyshev, V.N.; Horvath, S. & Ferrucci, L. (2024), Validation of biomarkers of aging, Nature Medicine.
- Luna, J.L. de; Nounu, A.; Neumeyer, S.; Sinke, L.; Wilson, R.; Hellbach, F.; Matías-García, P.R.; Delerue, T.; Winkelmann, J.; Peters, A.; Thorand, B.; Beekman, M.; Heijmans, B.T.; Slagboom, E.; Gieger, C.; Linseisen, J. & Waldenberger, M. (2024), Epigenome-wide association study of dietary fatty acid intake, Clinical Epigenetics 16(1).
- Andreu-Sanchez, S.; Ahmad, S.; Kurilshikov, A.; Beekman, M.; Ghanbari, M.; Faassen, M. van; Munckhof, I.C.L. van den; Steur, M.; Harms, A.; Hankemeier, T.; Ikram, M.A.; Kavousi, M.; Voortman, T.; Kraaij, R.; Netea, M.G.; Rutten, J.H.W.; Riksen, N.P.; Zhernakova, A.; Kuipers, F.; Slagboom, P.E.; Duijn, C.M. van; Fu, J.Y. & Vojinovic, D. (2024), Unraveling interindividual variation of trimethylamine N-oxide and its precursors at the population level, iMeta.
- Sterenborg, R.B.T.M.; Steinbrenner, I.; Li, Y.; Bujnis, M.N.; Naito, T.; Marouli, E.; Galesloot, T.E.; Babajide, O.; Andreasen, L.; Astrup, A.; Asvold, B.O.; Bandinelli, S.; Beekman, M.; Beilby, J.P.; Bork-Jensen, J.; Boutin, T.; Brody, J.A.; Brown, S.J.; Brumpton, B.; Campbell, P.J.; Cappola, A.R.; Ceresini, G.; Chaker, L.; Chasman, D.; Concas, M.P.; Almeida, R.C. de; Cross, S.M.; Cucca, F.; Deary, I.J.; Kjaergaard, A.D.; Tcheugui, J.B.E.; Ellervik, C.; Eriksson, J.G.; Ferrucci, L.; Freudenberg, J.; Fuchsberger, C.; Gieger, C.; Giulianini, F.; Gögele, M.; Graham, S.E.; Grarup, N.; Gunjaca, I.; Hansen, T.; Harding, B.N.; Harris, S.E.; Haunso, S.; Hayward, C.; Hui, J.; Ittermann, T.; Jukema, J.W.; Kajantie, E.; Kanters, J.K.; Kårhus, L.L.; Kiemeney, L.A.L.M.; Kloppenburg, M.; Kühnel, B.; Lahti, J.; Langenberg, C.; Lapauw, B.; Leese, G.; Li, S.; Liewald, D.C.M.; Linneberg, A.; Lominchar, J.V.T.; Luan, J.A.; Martin, N.G.; Matana, A.; Meima, M.E.; Meitinger, T.; Meulenbelt, I.; Mitchell, B.D.; Mollehave, L.T.; Mora, S.; Naitza, S.; Nauck, M.; Netea-Maier, R.T.; Noordam, R.; Nursyifa, C.; Okada, Y.; Onano, S.; Papadopoulou, A.; Palmer, C.N.A.; Pattaro, C.; Pedersen, O.; Peters, A.; Pietzner, M.; Polasek, O.; Pramstaller, P.P.; Psaty, B.M.; Punda, A.; Ray, D.; Redmond, P.; Richards, J.B.; Ridker, P.M.; Russ, T.C.; Ryan, K.A.; Olesen, M.S.; Schultheiss, U.T.; Selvin, E.; Siddiqui, M.K.; Sidore, C.; Slagboom, P.E.; Sorensen, T.I.A.; Soto-Pedre, E.; Spector, T.D.; Spedicati, B.; Srinivasan, S.; Starr, J.M.; Stott, D.J.; Tanaka, T.; Torlak, V.; Trompet, S.; Tuhkanen, J.; Uitterlinden, A.G.; Akker, E.B. van den; Eynde, T. van den; Klauw, M.M. van der; Heemst, D. van; Verroken, C.; Visser, W.E.; Vojinovic, D.; Völzke, H.; Waldenberger, M.; Walsh, J.P.; Wareham, N.J.; Weiss, S.; Willer, C.J.; Wilson, S.G.; Wolffenbuttel, B.H.R.; Wouters, H.J.C.M.; Wright, M.J.; Yang, Q.; Zemunik, T.; Zhou, W.; Zhu, G.; Zöllner, S.; Smit, J.W.A.; Peeters, R.P.; Köttgen, A.; Teumer, A.; Medici, M.; Ghs DiscovEHR & Regeneron Genetics Ctr (2024), Multi-trait analysis characterizes the genetics of thyroid function and identifies causal associations with clinical implications, Nature Communications 15(1).
- Sluiskes, M.; Goeman, J.; Beekman, M.; Slagboom, E.; Akker, E. van den; Putter, H. & Rodríguez-Girondo, M. (2024), The AccelerAge framework: a new statistical approach to predict biological age based on time-to-event data, European Journal of Epidemiology.
- Karjalainen, M.K.; Karthikeyan, S.; Oliver-Williams, C.; Sliz, E.; Allara, E.; Fung, W.T.; Surendran, P.; Zhang, W.H.; Jousilahti, P.; Kristiansson, K.; Salomaa, V.; Goodwin, M.; Hughes, D.A.; Boehnke, M.; Silva, L.F.; Yin, X.Y.; Mahajan, A.; Neville, M.J.; Zuydam, N.R. van; Mutsert, R. de; Li-Gao, R.; Mook-Kanamori, D.O.; Demirkan, A.; Liu, J.; Noordam, R.; Trompet, S.; Chen, Z.M.; Kartsonaki, C.; Li, L.M.; Lin, K.; Hagenbeek, F.A.; Hottenga, J.J.; Pool, R.; Ikram, M.A.; Meurs, J. van; Haller, T.; Milaneschi, Y.; Kähönen, M.; Mishra, P.P.; Joshi, P.K.; Macdonald-Dunlop, E.; Mangino, M.; Zierer, J.; Acar, I.E.; Hoyng, C.B.; Lechanteur, Y.T.E.; Franke, L.; Kurilshikov, A.; Zhernakova, A.; Beekman, M.; Akker, E.B. van den; Kolcic, I.; Polasek, O.; Rudan, I.; Gieger, C.; Waldenberger, M.; Asselbergs, F.W.; Hayward, C.; Fu, J.Y.; Hollander, A.I. den; Menni, C.; Spector, T.D.; Wilson, J.F.; Lehtimäki, T.; Raitakari, O.T.; Penninx, B.W.J.H.; Esko, T.; Walters, R.G.; Jukema, J.W.; Sattar, N.; Ghanbari, M.; Dijk, K.W. van; Karpe, F.; McCarthy, M.I.; Laakso, M.; Järvelin, M.R.; Timpson, N.J.; Perola, M.; Kooner, J.S.; Chambers, J.C.; Duijn, C. van; Slagboom, P.E.; Boomsma, D.I.; Danesh, J.; Ala-Korpela, M.; Butterworth, A.S.; Kettunen, J.; China Kadoorie Biobank; Estonian Biobank Res Team & FinnGen (2024), Genome-wide characterization of circulating metabolic biomarkers, Nature.
- Todtenhaupt, P.; Franken, L.A.; Groene, S.G.; Hoolwerff, M. van; Meeren, L.E. van der; Klink, J.M.M. van; Roest, A.A.W.; Bruin, C. de; Ramos, Y.F.M.; Haak, M.C.; Lopriore, E.; Heijmans, B.T. & Pel, M. van (2023), A robust and standardized method to isolate and expand mesenchymal stromal cells from human umbilical cord, Cytotherapy 25(10): 1057-1068.
- Boone, I.; Tuerlings, M.; Almeida, R.C. de; Lehmann, J.; Ramos, Y.; Nelissen, R.; Slagboom, E.; Keizer, P. de & Meulenbelt, I. (2023), Identified senescence endotypes in aged cartilage are reflected in the blood metabolome, Geroscience.
- Berg, N. van den; Rodríguez-Girondo, M.; Dijk, I.K. van; Slagboom, P.E. & Beekman, M. (2023), Increasing number of long-lived ancestors marks a decade of healthspan extension and healthier metabolomics profiles, Nature Communications 14(1).
- Bizzarri, D.; Reinders, M.J.T.; Beekman, M.; Slagboom, P.E.; Akker, E.B. van den & BbmriNl (2023), Technical report, Metabolites 13(12).
- Bizzarri, D.; Reinders, M.J.T.; Beekman, M.; Slagboom, P.E.; Akker, E.B. van den & BbmriNl (2023), Technical Report: A Comprehensive Comparison between Different Quantification Versions of Nightingale Health's 1H-NMR Metabolomics Platform, Metabolites 13(12).
- Kavousi, M.; Bos, M.M.; Barnes, H.J.; Cardenas, C.L.L.; Wong, D.R.; Lu, H.J.; Hodonsky, C.J.; Landsmeer, L.P.L.; Turner, A.W.; Kho, M.; Hasbani, N.R.; Vries, P.S. de; Bowden, D.W.; Chopade, S.; Deelen, J.; Benavente, E.D.; Guo, X.Q.; Hofer, E.; Hwang, S.J.; Lutz, S.M.; Lyytikaeinen, L.P.; Slenders, L.; Smith, A.V.; Stanislawski, M.A.; Setten, J. van; Wong, Q.N.; Yanek, L.R.; Becker, D.M.; Beekman, M.; Budoff, M.J.; Feitosa, M.F.; Finan, C.; Hilliard, A.T.; Kardia, S.L.R.; Kovacic, J.C.; Kral, B.G.; Langefeld, C.D.; Launer, L.J.; Malik, S.; Hoesein, F.A.A.M.; Mokry, M.; Schmidt, R.; Smith, J.A.; Taylor, K.D.; Terry, J.G.; Grond, J. van der; Meurs, J. van; Vliegenthart, R.; Xu, J.Z.; Young, K.A.; Zilhao, N.R.; Zweiker, R.; Assimes, T.L.; Becker, L.C.; Bos, D.; Carr, J.J.; Cupples, L.A.; Kleijn, D.P.V. de; Winther, M. de; Ruijter, H.M. den; Fornage, M.; Freedman, B.I.; Gudnason, V.; Hingorani, A.D.; Hokanson, J.E.; Ikram, M.A.; Isgum, I.; Jacobs, D.R.; Kaehoenen, M.; Lange, L.A.; Lehtimaeki, T.; Pasterkamp, G.; Raitakari, O.T.; Schmidt, H.; Slagboom, P.E.; Uitterlinden, A.G.; Vernooij, M.W.; Bis, J.C.; Franceschini, N.; Psaty, B.M.; Post, W.S.; Rotter, J.I.; Bjoerkegren, J.L.M.; O'Donnell, C.J.; Bielak, L.F.; Peyser, P.A.; Malhotra, R.; Laan, S.W. van der & Miller, C.L. (2023), Multi-ancestry genome-wide study identifies effector genes and druggable pathways for coronary artery calcification, Nature Genetics.
- Costeira, R.; Evangelista, L.; Wilson, R.; Yan, X.Y.; Hellbach, F.; Sinke, L.; Christiansen, C.; Villicana, S.; Masachs, O.M.; Tsai, P.C.; Mangino, M.; Menni, C.; Berry, S.E.; Beekman, M.; Heemst, D. van; Slagboom, P.E.; Heijmans, B.T.; Suhre, K.; Kastenmueller, G.; Gieger, C.; Peters, A.; Small, K.S.; Linseisen, J.; Waldenberger, M. & Bell, J.T. (2023), Metabolomic biomarkers of habitual B vitamin intakes unveil novel differentially methylated positions in the human epigenome, Clinical Epigenetics 15(1).
- Holstein, Y. van; Berkmortel, P.J.E. van den; Trompet, S.; Heemst, D. van; Bos, F. van den; Roemeling-van Rhijn, M.R.V.; Glas, N.A. de; Beekman, M.; Slagboom, P.E.; Portielje, J.E.A.; Mooijaart, S.P. & Munster, B.C. van (2023), The association of blood biomarkers with treatment response and adverse health outcomes in older patients with solid tumors: A systematic review, Journal of Geriatric Oncology 14(7).
- Kuiper, L.M.; Polinder-Bos, H.A.; Bizzarri, D.; Vojinovic, D.; Vallerga, C.L.; Beekman, M.; Dollé, E.T.; Ghanbari, M.; Voortman, T.; Reinders, M.J.T.; Verschuren, W.M.M.; Slagboom, P.E.; Akker, E.B. van den & Meurs, J.B.J. van (2023), Epigenetic and Metabolomic Biomarkers for Biological Age: A Comparative Analysis of Mortality and Frailty Risk, The Journals of Gerontology, Series A: Biological Sciences and Medical Sciences 78(10): 1753-1762.
- Weihs, A.; Chaker, L.; Martin, T.C.; Braun, K.V.E.; Campbell, P.J.; Cox, S.R.; Fornage, M.; Gieger, C.; Grabe, H.J.; Grallert, H.; Harris, S.E.; Kuhnel, B.; Marioni, R.E.; Martin, N.G.; McCartney, D.L.; McRae, A.F.; Meisinger, C.; Meurs, J.B.J. van; Nano, J.; Nauck, M.; Peters, A.; Prokisch, H.; Roden, M.; Selvin, E.; Beekman, M.; Heemst, D. van; Slagboom, E.P.; Swenson, B.R.; Tin, A.; Tsai, P.C.; Uitterlinden, A.; Visser, W.E.; Volzke, H.; Waldenberger, M.; Walsh, J.P.; Kottgen, A.; Wilson, S.G.; Peeters, R.P.; Bell, J.T.; Medici, M. & Teumer, A. (2023), Epigenome-Wide Association Study Reveals CpG Sites Associated with Thyroid Function and Regulatory Effects on KLF9, Thyroid 33(3): 301-311.
- Dekkers, K.F.; Slieker, R.C.; Ioan-Facsinay, A.; Iterson, M. van; Ikram, M.A.; Greevenbroek, M.M.J. van; Veldink, J.H.; Franke, L.; Boomsma, D.I.; Slagboom, P.E.; Jukema, J.W.; Heijmans, B.T. & BIOS consortium (2023), Lipid-induced transcriptomic changes in blood link to lipid metabolism and allergic response, Nature Communications 14(1).
- Costeira, R.; Ruiz, L.D.; Sinke, L.; Christiansen, C.; Heijmans, B.; Slagboom, E.; Waldenberger, M.; Berry, S.; Ordovás, J.M. & Bell, J.T. (2023), Human DNA methylation trajectories of the postprandial metabolic response to food, Annals of Nutrition and Metabolism 79: 353-353.
- Giacconi, R.; Piacenza, F.; Aversano, V.; Zampieri, M.; Bürkle, A.; Villanueva, M.M.; Dollé, M.E.T.; Jansen, E.; Grune, T.; Gonos, E.S.; Franceschi, C.; Capri, M.; Weinberger, B.; Sikora, E.; Toussaint, O.; Debacq-Chainiaux, F.; Stuetz, W.; Slagboom, P.E.; Bernhardt, J.; Fernández-Sánchez, M.L.; Provinciali, M. & Malavolta, M. (2023), Uncovering the Relationship between Selenium Status, Age, Health, and Dietary Habits: Insights from a Large Population Study including Nonagenarian Offspring from the MARK-AGE Project, Nutrients 15(9).
- Kochlik, B.; Herpich, C.; Moreno-Villanueva, M.; Klaus, S.; Müller-Werdan, U.; Weinberger, B.; Fiegl, S.; Toussaint, O.; Debacq-Chainiaux, F.; Schön, C.; Bernhard, J.; Breusing, N.; Gonos, E.S.; Franceschi, C.; Capri, M.; Sikora, E.; Hervonen, A.; Hurme, M.; Slagboom, P.E.; Dolle, M.E.T.; Jansen, E.; Grune, T.; Bürkle, A. & Norman, K. (2023), Associations of circulating GDF15 with combined cognitive frailty and depression in older adults of the MARK-AGE study, Geroscience.
- Groene, S.G.; Gremmen, I.J.; Zwet, E.W. van; Roest, A.A.W.; Haak, M.C.; Klink, J.M.M. van; Lopriore, E.; Heijmans, B.T. & Bruin, C. de (2023), Fetal growth restriction inhibits childhood growth despite catch-up in discordant identical twins: an observational cohort study, European journal of endocrinology 189(2): 183-189.
- Walton, E.; Baltramonaityte, V.; Calhoun, V.; Heijmans, B.T.; Thompson, P.M. & Cecil, C.A.M. (2023), A systematic review of neuroimaging epigenetic research: calling for an increased focus on development, Molecular Psychiatry 28(7): 2839-2847.
- Schorr, K.; Agayn, V.; Vries, J. de; Groot, L.C.P.G.M. de; Beekman, M. & Slagboom, P.E. (2023), An unhealthful plant-based diet and circulating hsCRP levels are independently associated with lower physical well-being in older adults, Proceedings of the Nutrition Society 82(OCE5).
- Wiersema, J.M.; Kamphuis, A.E.P.; Rohling, J.H.T.; Kervezee, L.; Akintola, A.A.; Jansen, S.W.; Slagboom, P.E.; Heemst, D. van & Spoel, E. van der (2022), The association between continuous ambulatory heart rate, heart rate variability, and 24-h rhythms of heart rate with familial longevity and aging, Aging 14(18): 7223-7239.
- Buergel, T.; Steinfeldt, J.; Ruyoga, G.; Pietzner, M.; Bizzarri, D.; Vojinovic, D.; Belzen, J.U. zu; Loock, L.; Kittner, P.; Christmann, L.; Hollmann, N.; Strangalies, H.; Braunger, J.M.; Wild, B.; Chiesa, S.T.; Spranger, J.; Klostermann, F.; Akker, E.B. van den; Trompet, S.; Mooijaart, S.P.; Sattar, N.; Jukema, J.W.; Lavrijssen, B.; Kavousi, M.; Ghanbari, M.; Ikram, M.A.; Slagboom, E.; Kivimaki, M.; Langenberg, C.; Deanfield, J.; Eils, R. & Landmesser, U. (2022), Metabolomic profiles predict individual multidisease outcomes, Nature Medicine 28.
- Hellbach, F.; Sinke, L.; Costeira, R.; Baumeister, S.E.; Beekman, M.; Louca, P.; Leeming, E.R.; Mompeo, O.; Berry, S.; Wilson, R.; Wawro, N.; Freuer, D.; Hauner, H.; Peters, A.; Winkelmann, J.; Koenig, W.; Meisinger, C.; Waldenberger, M.; Heijmans, B.T.; Slagboom, P.E.; Bell, J.T. & Linseisen, J. (2022), Pooled analysis of epigenome-wide association studies of food consumption in KORA, TwinsUK and LLS, European Journal of Nutrition 62.
- Giacconi, R.; Laffon, B.; Costa, S.; Teixeira-Gomes, A.; Maggi, F.; Macera, L.; Spezia, P.G.; Piacenza, F.; Burkle, A.; Moreno-Villanueva, M.; Bonassi, S.; Valdiglesias, V.; Teixeira, J.P.; Dolle, M.E.T.; Rietman, M.L.; Jansen, E.; Grune, T.; Gonos, E.S.; Franceschi, C.; Capri, M.; Weinberger, B.; Sikora, E.; Stuetz, W.; Toussaint, O.; Debacq-Chainiaux, F.; Hervonen, A.; Hurme, M.; Slagboom, P.E.; Schon, C.; Bernhardt, J.; Breusing, N.; Pasaro, E.; Maseda, A.; Lorenzo-Lopez, L.; Millan-Calenti, J.C.; Provinciali, M. & Malavolta, M. (2022), Association of Torquetenovirus viremia with physical frailty and cognitive impairment in three independent European cohorts, Gerontology.
- Bizzarri, D.; Reinders, M.J.T.; Beekman, M.; Slagboom, P.E. & Akker, E.B. van den (2022), MiMIR, Bioinformatics 38(15): 3847-3849.
- Giacconi, R.; D'Aquila, P.; Malavolta, M.; Piacenza, F.; Burkle, A.; Villanueva, M.M.; Dolle, M.E.T.; Jansen, E.; Grune, T.; Gonos, E.S.; Franceschi, C.; Capri, M.; Gradinaru, D.; Grubeck-Loebenstein, B.; Sikora, E.; Stuetz, W.; Weber, D.; Toussaint, O.; Debacq-Chainiaux, F.; Hervonen, A.; Hurme, M.; Slagboom, P.E.; Schon, C.; Bernhardt, J.; Breusing, N.; Duncan, T.; Passarino, G.; Bellizzi, D. & Provinciali, M. (2022), Bacterial DNAemia in older participants and nonagenarian offspring and association with redox biomarkers , The Journals of Gerontology, Series A: Biological Sciences and Medical Sciences 78(1).
- Jonkman, T.H.; Dekkers, K.F.; Slieker, R.C.; Grant, C.D.; Ikram, M.A.; Greevenbroek, M.M.J. van; Franke, L.; Veldink, J.H.; Boomsma, D.I.; Slagboom, P.E.; Consortium, B.I.O.S. & Heijmans, B.T. (2022), Functional genomics analysis identifies T and NK cell activation as a driver of epigenetic clock progression, Genome Biology 23(1).
- Bizzarri, D.; Reinders, M.J.T.; Beekman, M.; Slagboom, P.E.; BBMRI-NL & Akker, E.B. van den (2022), 1H-NMR metabolomics-based surrogates to impute common clinical risk factors and endpoints, EBioMedicine 75.
- Spek, A. van der; Karamujic-Comic, H.; Pool, R.; Bot, M.; Beekman, M.; Garmaeva, S.; Arp, P.P.; Henkelman, S.; Liu, J.; Alves, A.C.; Willemsen, G.; Grootheest, G. van; Aubert, G.; Ikram, M.A.; Jarvelin, M.R.; Lansdorp, P.; Uitterlinden, A.G.; Zhernakova, A.; Slagboom, P.E.; Penninx, B.W.J.H.; Boomsma, D.I.; Amin, N.; Duijn, C.M. van & BBMRI Metabolomics Consortium (2022), Fat metabolism is associated with telomere length in six population-based studies, Human Molecular Genetics 31(7): 1159-1170.
- Watson, H.J.; Thornton, L.M.; Yilmaz, Z.; Baker, J.H.; Coleman, J.R.I.; Adan, R.A.H.; Alfredsson, L.; Andreassen, O.A.; Ask, H.; Berrettini, W.H.; Boehnke, M.; Boehm, I.; Boni, C.; Buehren, K.; Bulant, J.; Burghardt, R.; Chang, X.; Cichon, S.; Cone, R.D.; Courtet, P.; Crow, S.; Crowley, J.J.; Danner, U.N.; Zwaan, M. de; Dedoussis, G.; DeSocio, J.E.; Dick, D.M.; Dikeos, D.; Dina, C.; Djurovic, S.; Dmitrzak-Weglarz, M.; Docampo-Martinez, E.; Duriez, P.; Egberts, K.; Ehrlich, S.; Eriksson, J.G.; Escaramís, G.; Esko, T.; Estivill, X.; Farmer, A.; Fernández-Aranda, F.; Fichter, M.M.; Föcker, M.; Foretova, L.; Forstner, A.J.; Frei, O.; Gallinger, S.; Giegling, I.; Giuranna, J.; Gonidakis, F.; Gorwood, P.; Gratacòs, M.; Guillaume, S.; Guo, Y.R.; Hakonarson, H.; Hauser, J.; Havdahl, A.; Hebebrand, J.; Helder, S.G.; Herms, S.; Herpertz-Dahlmann, B.; Herzog, W.; Hinney, A.; Hübel, C.; Hudson, J.I.; Imgart, H.; Jamain, S.; Janout, V.; Jiménez-Murcia, S.; Jones, I.R.; Julià, A.; Kalsi, G.; Kaminská, D.; Kaprio, J.; Karhunen, L.; Kas, M.J.H.; Keel, P.K.; Kennedy, J.L.; Keski-Rahkonen, A.; Kiezebrink, K.; Klareskog, L.; Klump, K.L.; Knudsen, G.P.S.; Via, M.C. la; Hellard, S. le; Leboyer, M.; Li, D.; Lilenfeld, L.; Lin, B.C.; Lissowska, J.; Luykx, J.; Magistretti, P.; Maj, M.; Marsal, S.; Marshall, C.R.; Mattingsdal, M.; Meulenbelt, I.; Micali, N.; Mitchell, K.S.; Monteleone, A.M.; Monteleone, P.; Myers, R.; Navratilova, M.; Ntalla, I.; O'Toole, J.K.; Ophoff, R.A.; Padyukov, L.; Pantel, J.; Papezová, H.; Pinto, D.; Raevuori, A.; Ramoz, N.; Reichborn-Kjennerud, T.; Ricca, V.; Ripatti, S.; Ripke, S.; Ritschel, F.; Roberts, M.; Rotondo, A.; Rujescu, D.; Rybakowski, F.; Scherag, A.; Scherer, S.W.; Schmidt, U.; Scott, L.J.; Seitz, J.; Silén, Y.; Slachtová, L.; Slagboom, P.E.; Slof-Op 't Landt, C.T.; Slopien, A.; Sorbi, S.; Swiatkowska, B.; Tortorella, A.; Tozzi, F.; Treasure, J.; Tsitsika, A.; Tyszkiewicz-Nwafor, M.; Tziouvas, K.; Elburg, A.A. van; Furth, E.F. van; Walton, E.; Widen, E.; Zerwas, S.; Zipfel, S.; Bergen, A.W.; Boden, J.M.; Brandt, H.; Crawford, S.; Halmi, K.A.; Horwood, L.J.; Johnson, C.; Kaplan, A.S.; Kaye, W.H.; Mitchell, J.E.; Olsen, C.M.; Pearson, J.F.; Pedersen, N.L.; Strober, M.; Werge, T.; Whiteman, D.C.; Woodside, D.B.; Gordon, S.; Maguire, S.; Larsen, J.T.; Parker, R.; Petersen, L.; Jordan, J.; Kennedy, M.; Wade, T.D.; Birgegård, A.; Lichtenstein, P.; Landén, M.; Martin, N.G.; Mortensen, P.B.; Breen, G. & Bulik, C.M. (2022), Common genetic variation and age of onset of anorexia nervosa, Biological Society Global Open Science 2(4): 368-378.
- Paraschiakos, S.; Sa, C.R. de; Okai, J.; Slagboom, P.E.; Beekman, M. & Knobbe, A. (2022), A recurrent neural network architecture to model physical activity energy expenditure in older people, Data Mining and Knowledge Discovery 36.
- Bogaards, F.A.; Gehrmann, T.; Beekman, M.; Akker, E. ben van den; Rest, O. van de; Hangelbroek, R.W.J.; Noordam, R.; Mooijaart, S.P.; Groot, L.C.P.G.M. de; Reinders, M.J.T. & Slagboom, P.E. (2022), PLIS: a metabolomic response monitor to a lifestyle intervention study in older adults, The FASEB Journal 36(11).
- Groene, S.G.; Openshaw, K.M.; Jansén-Storbacka, L.R.; Slaghekke, F.; Haak, M.C.; Heijmans, B.T.; Klink, J.M.M. van; Roest, A.A.W.; Meeren, L.E. van der & Lopriore, E. (2022), Impact of placental sharing and large bidirectional anastomoses on birthweight discordance in monochorionic twins: a retrospective cohort study in 449 cases, American Journal of Obstetrics & Gynecology 227(5).
- Morwani-Mangnani, J.; Giannos, P.; Belzer, C.; Beekman, M.; Slagboom, P.E. & Prokopidis, K. (2022), Gut microbiome changes due to sleep disruption in older and younger individuals: a case for sarcopenia?, SLEEP 45(12).
- Niehues, A.; Bizzarri, D.; Reinders, M.J.T.; Slagboom, P.E.; Gool, A.J. van; Akker, E.B. van den; Hoen, P.A.C.'.; BBMRI-NL BIOS Consortium & BBMRI-NL Metabolomics Consortium (2022), Metabolomic predictors of phenotypic traits can replace and complement measured clinical variables in population-scale expression profiling studies, BMC Genomics 23(1).
- Boer, C.G.; Hatzikotoulas, K.; Southam, L.; Stefansdottir, L.; Zhang, Y.F.; Almeida, R.C. de; Wu, T.T.; Zheng, J.; Hartley, A.; Teder-Laving, M.; Skogholt, A.H.; Terao, C.; Zengini, E.; Alexiadis, G.; Barysenka, A.; Bjornsdottir, G.; Gabrielsen, M.E.; Gilly, A.; Ingvarsson, T.; Johnsen, M.B.; Jonsson, H.; Kloppenburg, M.; Luetge, A.; Lund, S.H.; Magi, R.; Mangino, M.; Nelissen, R.R.G.H.H.; Shivakumar, M.; Steinberg, J.; Takuwa, H.; Thomas, L.F.; Tuerlings, M.; Babis, G.C.; Cheung, J.P.Y.; Kang, J.H.; Kraft, P.; Lietman, S.A.; Samartzis, D.; Slagboom, P.E.; Stefansson, K.; Thorsteinsdottir, U.; Tobias, J.H.; Uitterlinden, A.G.; Winsvold, B.; Zwart, J.A.; Smith, G.D.; Sham, P.C.; Thorleifsson, G.; Gaunt, T.R.; Morris, A.P.; Valdes, A.M.; Tsezou, A.; Cheah, K.S.E.; Ikegawa, S.; Hveem, K.; Esko, T.; Wilkinson, J.M.; Meulenbelt, I.; Lee, M.T.M.; Meurs, J.B.J. van; Styrkarsdottir, U.; Zeggini, E.; arcOGEN Consortium; HUNT All-In Pain; ARGO Consortium & Regeneron Genetics Ctr (2021), Deciphering osteoarthritis genetics across 826,690 individuals from 9 populations, Cell 184(18): 4784-+.
- Hassouneh, F.; Goldeck, D.; Pera, A.; Heemst, D. van; Slagboom, P.E.; Pawelec, G. & Solana, R. (2021), Functional changes of T-cell subsets with age and CMV infection, International Journal of Molecular Sciences 22(18).
- Bos, M.M.; Goulding, N.J.; Lee, M.; Hofman, A.; Bot, M.; Pool, R.; Vijfhuizen, L.; Zhang, X.; Li, C.; Mustafa, R.; Neville, M.J.; Li-Gao, R.; Trompet, S.; Beekman, M.; Biermasz, N.R.; Boomsma, D.I.; Boer, I. de; Christodoulides, C.; Dehghan, A.; Dijk, K.W. van; Ford, I.; Ghanbari, M.; Heijmans, B.T.; Ikram, M.A.; Jukema, J.W.; Mook-Kanamori, D.O.; Karpe, F.; Luik, A.I.; Lumey, L.; Maagdenberg, A.M. van den; Mooijaart, S.P.; Mutsert, R. de; Penninx, B.W.J.H.; Rensen, P.C.N.; Richmond, R.C.; Rosendaal, F.R.; Sattar, N.; Schoevers, R.; Slagboom, P.E.; Terwindt, G.M.; Thesing, C.S.; Wade, K.; Wijsman, C.A.; Willemsen, G.; Zinderman, A.; Verwoert, G.C.; Noordam, R. & Lawlor, D.A. (2021), INVESTIGATING THE RELATIONSHIPS BETWEEN UNFAVORABLE SLEEP AND METABOLOMIC TRAITS: EVIDENCE FROM MULTI-COHORT MULTIVARIABLE REGRESSION AND MENDELIAN RANDOMIZATION ANALYSES, Atherosclerosis 331: E42-E42.
- Vliet, N.A. van; Bos, M.M.; Thesing, C.S.; Chaker, L.; Pietzner, M.; Houtman, E.; Neville, M.J.; Li-Gao, R.; Trompet, S.; Mustafa, R.; Ahmadizar, F.; Beekman, M.; Bot, M.; Budde, K.; Christodoulides, C.; Dehghan, A.; Delles, C.; Elliott, P.; Evangelou, M.; Gao, H.; Ghanbari, M.; Herwaarden, A.E. van; Ikram, M.A.; Jaeger, M.; Jukema, J.W.; Karaman, I.; Karpe, F.; Kloppenburg, M.; Meessen, J.M.T.A.; Meulenbelt, I.; Milaneschi, Y.; Mooijaart, S.P.; Mook-Kanamori, D.O.; Netea, M.G.; Netea-Maier, R.T.; Peeters, R.P.; Penninx, B.W.J.H.; Sattar, N.; Slagboom, P.E.; Suchiman, H.E.D.; Volzke, H.; Dijk, K.W. van; Noordam, R.; Heemst, D. van & BBMRI Metabolomics Consortium (2021), Higher thyrotropin leads to unfavorable lipid profile and somewhat higher cardiovascular disease risk, BMC Medicine 19(1).
- Dongen, J. van; Gordon, S.D.; McRae, A.F.; Odintsova, V.V.; Mbarek, H.; Breeze, C.E.; Sugden, K.; Lundgren, S.; Castillo-Fernandez, J.E.; Hannon, E.; Moffitt, T.E.; Hagenbeek, F.A.; Beijsterveldt, C.E.M. van; Hottenga, J.J.; Tsai, P.C.; Min, J.L.; Hemani, G.; Ehli, E.A.; Paul, F.; Stern, C.D.; Heijmans, B.T.; Slagboom, P.E.; Daxinger, L.; Maarel, S.M. van der; Geus, E.J.C. de; Willemsen, G.; Montgomery, G.W.; Reversade, B.; Ollikainen, M.; Kaprio, J.; Spector, T.D.; Bell, J.T.; Mill, J.; Caspi, A.; Martin, N.G.; Boomsma, D.I.; Bios Consortium & Genetics DNA Methylation Consortiu (2021), Identical twins carry a persistent epigenetic signature of early genome programming, Nature Communications 12(1).
- Wang, W.; Dijk, K.W. van; Wijsman, C.A.; Rozing, M.P.; Mooijaart, S.P.; Beekman, M.; Slagboom, P.E.; Jukema, J.W. & Noordam, R. (2021), DIFFERENTIAL INSULIN SENSITIVITY OF NMR-BASED METABOLOMIC MEASURES IN A TWO-STEP HYPERINSULINEMIC EUGLYCEMIC CLAMP STUDY, Atherosclerosis 331: E44-E45.
- Stokes, C.S.; Weber, D.; Wagenpfeil, S.; Stuetz, W.; Moreno-Villanueva, M.; Dolle, M.E.T.; Jansen, E.; Gonos, E.S.; Bernhardt, J.; Grubeck-Loebenstein, B.; Fiegl, S.; Sikora, E.; Toussaint, O.; Debacq-Chainiaux, F.; Capri, M.; Hervonen, A.; Slagboom, P.E.; Breusing, N.; Frank, J.; Burkle, A.; Franceschi, C. & Grune, T. (2021), Association between fat-soluble vitamins and self-reported health status: a cross-sectional analysis of the MARK-AGE cohort, British Journal of Nutrition.
- Groene, S.G.; Spekman, J.A.; Pas, A.B. te; Heijmans, B.T.; Haak, M.C.; Klink, J.M.M. van; Roest, A.A.W. & Lopriore, E. (2021), Respiratory distress syndrome and bronchopulmonary dysplasia after fetal growth restriction, EClinicalMedicine 32.
- Maas, S.C.E.; Vidaki, A.; Teumer, A.; Costeira, R.; Wilson, R.; Dongen, J. van; Beekman, M.; Volker, U.; Grabe, H.J.; Kunze, S.; Ladwig, K.H.; Meurs, J.B.J. van; Uitterlinden, A.G.; Voortman, T.; Boomsma, D.I.; Slagboom, P.E.; Heemst, D. van; Kallen, C.J.H. van der; Berg, L.H. van den; Waldenberger, M.; Volzke, H.; Peters, A.; Bell, J.T.; Ikram, M.A.; Ghanbari, M. & Kayser, M. (2021), Validating biomarkers and models for epigenetic inference of alcohol consumption from blood, Clinical Epigenetics 13(1).
- Mulder, R.H.; Neumann, A.; Cecil, C.A.M.; Walton, E.; Houtepen, L.C.; Simpkin, A.J.; Rijlaarsdam, J.; Heijmans, B.T.; Gaunt, T.R.; Felix, J.F.; Jaddoe, V.W.V.; Bakermans-Kranenburg, M.J.; Tiemeier, H.; Relton, C.L.; IJzendoorn, M.H. van & Suderman, M. (2021), Epigenome-wide change and variation in DNA methylation in childhood, Human Molecular Genetics 30(1): 119-134.
- Vliet, N.A. van; Heemst, D. van; Almeida, O.P.; Asvold, B.O.; Aubert, C.E.; Bae, J. bin; Barnes, L.E.; Bauer, D.C.; Blauw, G.J.; Brayne, C.; Cappola, A.R.; Ceresini, G.; Comijs, H.C.; Dartigues, J.F.; Degryse, J.M.; Dullaart, R.P.F.; Eersel, M.E.A. van; Elzen, W.P.J. den; Ferrucci, L.; Fink, H.A.; Flicker, L.; Grabe, H.J.; Han, J.W.; Helmer, C.; Huisman, M.; Ikram, M.A.; Imaizumi, M.; Jongh, R.T. de; Jukema, J.W.; Kim, K.W.; Kuller, L.H.; Lopez, O.L.; Mooijaart, S.P.; Moon, J.H.; Moutzouri, E.; Nauck, M.; Parle, J.; Peeters, R.P.; Samuels, M.H.; Schmidt, C.O.; Schminke, U.; Slagboom, P.E.; Stordal, E.; Vaes, B.; Volzke, H.; Westendorp, R.G.J.; Yamada, M.; Yeap, B.B.; Rodondi, N.; Gussekloo, J.; Trompet, S. & Thyroid Studies Collaboration (2021), Association of Thyroid dysfunction with cognitive function an individual participant data analysis, JAMA Internal Medicine 181(11).
- Albalak, G.; Stijntjes, M.; Wijsman, C.A.; Slagboom, P.E.; Ouderaa, F.J. van der; Mooijaart, S.P.; Heemst, D. van & Noordam, R. (2021), Timing of objectively-collected physical activity in relation to body weight and metabolic health in sedentary older people: a cross-sectional and prospective analysis, International Journal of Obesity.
- D'Aquila, P.; Giacconi, R.; Malavolta, M.; Piacenza, F.; Burkle, A.; Villanueva, M.M.; Dolle, M.E.T.; Jansen, E.; Grune, T.; Gonos, E.S.; Franceschi, C.; Capri, M.; Grubeck-Loebenstein, B.; Sikora, E.; Toussaint, O.; Debacq-Chainiaux, F.; Hervonen, A.; Hurme, M.; Slagboom, P.E.; Schon, C.; Bernhardt, J.; Breusing, N.; Passarino, G.; Provinciali, M. & Bellizzi, D. (2021), Microbiome in blood samples from the general population recruited in the MARK-AGE project, Frontiers in Microbiology 12.
- Reilly, N.A.; Lutgens, E.; Kuiper, J.; Heijmans, B.T. & Jukema, J.W. (2021), Effects of fatty acids on T cell function, Nature Reviews Cardiology 18.
- Vosa, U.; Claringbould, A.; Westra, H.J.; Bonder, M.J.; Deelen, P.; Zeng, B.; Kirsten, H.; Saha, A.; Kreuzhuber, R.; Yazar, S.; Brugge, H.; Oelen, R.; Vries, D.H. de; Wijst, M.G.P. van der; Kasela, S.; Pervjakova, N.; Alves, I.; Fave, M.J.; Agbessi, M.; Christiansen, M.W.; Jansen, R.; Seppala, I.; Tong, L.; Teumer, A.; Schramm, K.; Hemani, G.; Verlouw, J.; Yaghootkar, H.; Flitman, R.S.; Brown, A.; Kukushkina, V.; Kalnapenkis, A.; Rueger, S.; Porcu, E.; Kronberg, J.; Kettunen, J.; Lee, B.; Zhang, F.T.; Qi, T.; Hernandez, J.A.; Arindrarto, W.; Beutner, F.; Dmitrieva, J.; Elansary, M.; Fairfax, B.P.; Georges, M.; Heijmans, B.T.; Hewitt, A.W.; Kahonen, M.; Kim, Y.; Knight, J.C.; Kovacs, P.; Krohn, K.; Li, S.; Loeffler, M.; Marigorta, U.M.; Mei, H.L.; Momozawa, Y.; Muller-Nurasyid, M.; Nauck, M.; Nivard, M.G.; Penninx, B.W.J.H.; Pritchard, J.K.; Raitakari, O.T.; Rotzschke, O.; Slagboom, E.P.; Stehouwer, C.D.A.; Stumvoll, M.; Sullivan, P.; Hoen, P.A.C. 't; Thiery, J.; Tonjes, A.; Dongen, J. van; Iterson, M. van; Veldink, J.H.; Volker, U.; Warmerdam, R.; Wijmenga, C.; Swertz, M.; Andiappan, A.; Montgomery, G.W.; Ripatti, S.; Perola, M.; Kutalik, Z.; Dermitzakis, E.; Bergmann, S.; Frayling, T.; Meurs, J. van; Prokisch, H.; Ahsan, H.; Pierce, B.L.; Lehtimaki, T.; Boomsma, D.I.; Psaty, B.M.; Gharib, S.A.; Awadalla, P.; Milani, L.; Ouwehand, W.H.; Downes, K.; Stegle, O.; Battle, A.; Visscher, P.M.; Yang, J.; Scholz, M.; Powell, J.; Gibson, G.; Esko, T.; Franke, L.; BIOS Consortium & i2QTL Consortium (2021), Large-scale cis- and trans-eQTL analyses identify thousands of genetic loci and polygenic scores that regulate blood gene expression, Nature Genetics 53(9): 1300-+.
- Vliet, N.A. van; Bos, M.M.; Thesing, C.S.; Chaker, L.; Pietzner, M.; Houtman, E.; Neville, M.J.; Li-Gao, R.; Trompet, S.; Mustafa, R.; Ahmadizar, F.; Beekman, M.; Bot, M.; Budde, K.; Christodoulides, C.; Dehghan, A.; Delles, C.; Elliott, P.; Evangelou, M.; Gao, H.; Ghanbari, M.; Herwaarden, A.E. van; Ikram, M.A.; Jaeger, M.; Jukema, J.W.; Karaman, I.; Karpe, F.; Kloppenburg, M.; Meessen, J.M.T.A.; Meulenbelt, I.; Milaneschi, Y.; Mooijaart, S.P.; Mook-Kanamori, D.O.; Netea, M.G.; Netea-Maier, R.T.; Peeters, R.P.; Penninx, B.W.J.H.; Sattar, N.; Slagboom, P.E.; Suchiman, H.E.D.; Volzke, H.; Dijk, K.W. van & Noordam, R. (2021), HIGHER THYROID STIMULATING HORMONE LEADS TO CARDIOVASCULAR DISEASE AND AN UNFAVORABLE LIPID PROFILE: EVIDENCE FROM MULTI-COHORT MENDELIAN RANDOMIZATION AND METABOLOMIC PROFILING, Atherosclerosis 331: E40-E40.
- Piacenza, F.; Giacconi, R.; Costarelli, L.; Basso, A.; Burkle, A.; Moreno-Villanueva, M.; Dolle, M.E.T.; Jansen, E.; Grune, T.; Weber, D.; Stuetz, W.; Gonos, E.S.; Schon, C.; Bernhardt, J.; Grubeck-Loebenstein, B.; Sikora, E.; Toussaint, O.; Debacq-Chainiaux, F.; Franceschi, C.; Capri, M.; Hervonen, A.; Hurme, M.; Slagboom, E.; Breusing, N.; Mocchegiani, E. & Malavolta, M. (2021), Age, Sex, and BMI Influence on Copper, Zinc, and Their Major Serum Carrier Proteins in a Large European Population Including Nonagenarian Offspring From MARK-AGE Study, The Journals of Gerontology, Series A: Biological Sciences and Medical Sciences 76(12): 2097-2106.
- Tobi, E.W.; Almqvist, C.; Hedman, A.; Andolf, E.; Holte, J.; Olofsson, J.I.; Wramsby, H.; Wramsby, M.; Pershagen, G.; Heijmans, B.T. & Iliadou, A.N. (2021), DNA methylation differences at birth after conception through ART, Human Reproduction 36(1): 248-259.
- Min, J.L.; Hemani, G.; Hannon, E.; Dekkers, K.F.; Castillo-Fernandez, J.; Luijk, R.; Carnero-Montoro, E.; Lawson, D.J.; Burrows, K.; Suderman, M.; Bretherick, A.D.; Richardson, T.G.; Klughammer, J.; Iotchkova, V.; Sharp, G.; Khleifat, A. al; Shatunov, A.; Iacoangeli, A.; McArdle, W.L.; Ho, K.M.; Kumar, A.; Soderhall, C.; Soriano-Tarraga, C.; Giralt-Steinhauer, E.; Kazmi, N.; Mason, D.; McRae, A.F.; Corcoran, D.L.; Sugden, K.; Kasela, S.; Cardona, A.; Day, F.R.; Cugliari, G.; Viberti, C.; Guarrera, S.; Lerro, M.; Gupta, R.; Bollepalli, S.; Mandaviya, P.; Zeng, Y.N.; Clarke, T.K.; Walker, R.M.; Schmoll, V.; Czamara, D.; Ruiz-Arenas, C.; Rezwan, F.I.; Marioni, R.E.; Lin, T.; Awaloff, Y.; Germain, M.; Aissi, D.; Zwamborn, R.; Eijk, K. van; Dekker, A.; Dongen, J. van; Hottenga, J.J.; Willemsen, G.; Xu, C.J.; Barturen, G.; Catala-Moll, F.; Kerick, M.; Wang, C.; Melton, P.; Elliott, H.R.; Shin, J.; Bernard, M.; Yet, I.; Smarts, M.; Gorrie-Stone, T.; Shaw, C.; Chalabi, A. al; Ring, S.M.; Pershagen, G.; Melen, E.; Jimenez-Conde, J.; Roquer, J.; Lawlor, D.A.; Wright, J.; Martin, N.G.; Montgomery, G.W.; Moffitt, T.E.; Poulton, R.; Esko, T.; Milani, L.; Metspalu, A.; Perry, J.R.B.; Ong, K.K.; Wareham, N.J.; Matullo, G.; Sacerdote, C.; Panico, S.; Caspi, A.; Arseneault, L.; Gagnon, F.; Ollikainen, M.; Kaprio, J.; Felix, J.F.; Rivadeneira, F.; Tiemeier, H.; IJzendoorn, M.H. van; Uitterlinden, A.G.; Jaddoe, V.W.V.; Hale, C.; McIntosh, A.M.; Evans, K.L.; Murray, A.; Raikkonen, K.; Lahti, J.; Nohr, E.A.; Sorensen, T.I.A.; Hansen, T.; Morgen, C.S.; Binder, E.B.; Lucae, S.; Gonzalez, J.R.; Bustamante, M.; Sunyer, J.; Holloway, J.W.; Karmaus, W.; Zhang, H.M.; Deary, I.J.; Wray, N.R.; Starr, J.M.; Beekman, M.; VanHeemst, D.; Slagboom, P.E.; Morange, P.E.; Tregouet, D.A.; Veldink, J.H.; Davies, G.E.; Geus, E.J.C. de; Boomsma, D.I.; Vonk, J.M.; Brunekreef, B.; Koppelman, G.H.; Alarcon-Riquelme, M.E.; Huang, R.C.; Pennell, C.E.; Meurs, J. van; Ikram, M.A.; Hughes, A.D.; Tillin, T.; Chaturvedi, N.; Pausova, Z.; Paus, T.; Spector, T.D.; Kumari, M.; Schalkwyk, L.C.; Visscher, P.M.; Smith, G.D.; Bock, C.; Gaunt, T.R.; Bell, J.T.; Heijmans, B.T.; Mill, J.; Relton, C.L. & BIOS Consortium (2021), Genomic and phenotypic insights from an atlas of genetic effects on DNA methylation, Nature Genetics 53(9): 1311-+.
- Kananen, L.; Enroth, L.; Raitanen, J.; Jylhava, J.; Burkle, A.; Moreno-Villanueva, M.; Bernhardt, J.; Toussaint, O.; Grubeck-Loebenstein, B.; Malavolta, M.; Basso, A.; Piacenza, F.; Collino, S.; Gonos, E.S.; Sikora, E.; Gradinaru, D.; Jansen, E.H.J.M.; Dolle, M.E.T.; Salmon, M.; Stuetz, W.; Weber, D.; Grune, T.; Breusing, N.; Simm, A.; Capri, M.; Franceschi, C.; Slagboom, P.E.; Talbot, D.C.S.; Libert, C.; Koskinen, S.; Bruunsgaard, H.; Hansen, A.M.; Lund, R.; Hurme, M. & Jylha, M. (2021), Self-rated health in individuals with and without disease is associated with multiple biomarkers representing multiple biological domains, Scientific Reports 11(1).
- Pelsma, I.C.M.; Claessen, K.M.J.A.; Slagboom, P.E.; Heemst, D. van; Pereira, A.M.; Kroon, H.; Ramos, Y.F.M.; Kloppenburg, M.; Biermasz, N.R. & Meulenbelt, I.M. (2021), Variants of FOXO3 and RPA3 genes affecting IGF-1 levels alter the risk of development of primary osteoarthritis, European Journal of Endocrinology 184(1): 29-39.
- Chen, J.; Spracklen, C.N.; Marenne, G.; Varshney, A.; Corbin, L.J.; Luan, J.A.; Willems, S.M.; Wu, Y.; Zhang, X.S.; Horikoshi, M.; Boutin, T.S.; Magi, R.; Waage, J.; Li-Gao, R.F.; Chan, K.H.K.; Yao, J.; Anasanti, M.D.; Chu, A.Y.; Claringbould, A.; Heikkinen, J.; Hong, J.; Hottenga, J.J.; Huo, S.F.; Kaakinen, M.A.; Louie, T.; Marz, W.; Moreno-Macias, H.; Ndungu, A.; Nelson, S.C.; Nolte, I.M.; North, K.E.; Raulerson, C.K.; Ray, D.; Rohde, R.; Rybin, D.; Schurmann, C.; Sim, X.L.; Southam, L.; Stewart, I.D.; Wang, C.A.; Wang, Y.J.; Wu, P.T.; Zhang, W.H.; Ahluwalia, T.S.; Appel, E.V.R.; Bielak, L.F.; Brody, J.A.; Burtt, N.P.; Cabrera, C.P.; Cade, B.E.; Chai, J.F.; Chai, X.R.; Chang, L.C.; Chen, C.H.; Chen, B.H.; Chitrala, K.N.; Chiu, Y.F.; Haan, H.G. de; Delgado, G.E.; Demirkan, A.; Duan, Q.; Engmann, J.; Fatumo, S.A.; Gayan, J.; Giulianini, F.; Gong, J.H.; Gustafsson, S.; Hai, Y.; Hartwig, F.P.; He, J.; Heianza, Y.; Huang, T.; Huerta-Chagoya, A.; Hwang, M.Y.; Jensen, R.A.; Kawaguchi, T.; Kentistou, K.A.; Kim, Y.J.; Kleber, M.E.; Kooner, I.K.; Lai, S.Q.; Lange, L.A.; Langefeld, C.D.; Lauzon, M.; Li, M.; Ligthart, S.; Liu, J.; Loh, M.; Long, J.R.; Lyssenko, V.; Mangino, M.; Marzi, C.; Montasser, M.E.; Nag, A.; Nakatochi, M.; Noce, D.; Noordam, R.; Pistis, G.; Preuss, M.; Raffield, L.; Rasmussen-Torvik, L.J.; Rich, S.S.; Robertson, N.R.; Rueedi, R.; Ryan, K.; Sanna, S.; Saxena, R.; Schraut, K.E.; Sennblad, B.; Setoh, K.; Smith, A.V.; Sparso, T.; Strawbridge, R.J.; Takeuchi, F.; Tan, J.Y.; Trompet, S.; Akker, E. van den; Most, P.J. van der; Verweij, N.; Vogel, M.; Wang, H.M.; Wang, C.L.; Wang, N.; Warren, H.R.; Wen, W.Q.; Wilsgaard, T.; Wong, A.; Wood, A.R.; Xie, T.; Zafarmand, M.H.; Zhao, J.H.; Zhao, W.; Amin, N.; Arzumanyan, Z.; Astrup, A.; Bakker, S.J.L.; Baldassarre, D.; Beekman, M.; Bergman, R.N.; Bertoni, A.; Bluher, M.; Bonnycastle, L.L.; Bornstein, S.R.; Bowden, D.W.; Cai, Q.Y.; Campbell, A.; Campbell, H.; Chang, Y.C.; Geus, E.J.C. de; Dehghan, A.; , S.F. du; Eiriksdottir, G.; Farmaki, A.E.; Franberg, M.; Fuchsberger, C.; Gao, Y.T.; Gjesing, A.P.; Goel, A.; Han, S.; Hartman, C.A.; Herder, C.; Hicks, A.A.; Hsieh, C.H.; Hsueh, W.A.; Ichihara, S.; Igase, M.; Ikram, M.A.; Johnson, W.C.; Jorgensen, M.E.; Joshi, P.K.; Kalyani, R.R.; Kandeel, F.R.; Katsuya, T.; Khor, C.C.; Kiess, W.; Kolcic, I.; Kuulasmaa, T.; Kuusisto, J.; Lall, K.; Lam, K.; Lawlor, D.A.; Lee, N.R.; Lemaitre, R.N.; Li, H.L.; Lin, S.Y.; Lindstrom, J.; Linneberg, A.; Liu, J.J.; Lorenzo, C.; Matsubara, T.; Matsuda, F.; Mingrone, G.; Mooijaart, S.; Moon, S.; Nabika, T.; Nadkarni, G.N.; Nadler, J.L.; Nelis, M.; Neville, M.J.; Norris, J.M.; Ohyagi, Y.; Peters, A.; Peyser, P.A.; Polasek, O.; Qi, Q.B.; Raven, D.; Reilly, D.F.; Reiner, A.; Rivideneira, F.; Roll, K.; Rudan, I.; Sabanayagam, C.; Sandow, K.; Sattar, N.; Schurmann, A.; Shi, J.X.; Stringham, H.M.; Taylor, K.D.; Teslovich, T.M.; Thuesen, B.; Timmers, P.R.H.J.; Tremoli, E.; Tsai, M.Y.; Uitterlinden, A.; Dam, R.M. van; Heemst, D. van; Vlieg, A.V.; Vliet-Ostaptchouk, J.V. van; Vangipurapu, J.; Vestergaard, H.; Wang, T.; Dijk, K.W. van; Zemunik, T.; Abecasis, G.R.; Adair, L.S.; Aguilar-Salinas, C.A.; Alarcon-Riquelme, M.E.; An, P.; Aviles-Santa, L.; Becker, D.M.; Beilin, L.J.; Bergmann, S.; Bisgaard, H.; Black, C.; Boehnke, M.; Boerwinkle, E.; Bohm, B.O.; Bonnelykke, K.; Boomsma, D.I.; Bottinger, E.P.; Buchanan, T.A.; Canouil, M.; Caulfield, M.J.; Chambers, J.C.; Chasman, D.I.; Chen, Y.D.I.; Cheng, C.Y.; Collins, F.S.; Correa, A.; Cucca, F.; Silva, H.J. de; Dedoussis, G.; Elmstahl, S.; Evans, M.K.; Ferrannini, E.; Ferrucci, L.; Florez, J.C.; Franks, P.W.; Frayling, T.M.; Froguel, P.; Gigante, B.; Goodarzi, M.O.; Gordon-Larsen, P.; Grallert, H.; Grarup, N.; Grimsgaard, S.; Groop, L.; Gudnason, V.; Guo, X.Q.; Hamsten, A.; Hansen, T.; Hayward, C.; Heckbert, S.R.; Horta, B.L.; Huang, W.; Ingelsson, E.; James, P.S.; Jarvelin, M.R.; Jonas, J.B.; Jukema, J.W.; Kaleebu, P. & Ka (2021), The trans-ancestral genomic architecture of glycemic traits, Nature Genetics 53(6): 840-+.
- Julkunen, H.; Cichonska, A.; Slagboom, P.E.; Wurtz, P. & Nightingale Hlth UK Biobank Initia (2021), Metabolic biomarker profiling for identification of susceptibility to severe pneumonia and COVID-19 in the general population, eLife 10.
- Ahluwalia, T.S.; Prins, B.P.; Abdollahi, M.; Armstrong, N.J.; Aslibekyan, S.; Bain, L.; Jefferis, B.; Baumert, J.; Beekman, M.; Ben-Shlomo, Y.; Bis, J.C.; Mitchell, B.D.; Geus, E. de; Delgado, G.E.; Marek, D.; Eriksson, J.; Kajantie, E.; Kanoni, S.; Kemp, J.P.; Lu, C.; Marioni, R.E.; McLachlan, S.; Milaneschi, Y.; Nolte, I.M.; Petrelis, A.M.; Porcu, E.; Sabater-Lleal, M.; Naderi, E.; Seppala, I.; Shah, T.; Singhal, G.; Standl, M.; Teumer, A.; Thalamuthu, A.; Thiering, E.; Trompet, S.; Ballantyne, C.M.; Benjamin, E.J.; Casas, J.P.; Toben, C.; Dedoussis, G.; Deelen, J.; Durda, P.; Engmann, J.; Feitosa, M.F.; Grallert, H.; Hammarstedt, A.; Harris, S.E.; Homuth, G.; Hottenga, J.J.; Jalkanen, S.; Jamshidi, Y.; Jawahar, M.C.; Jess, T.; Kivimaki, M.; Kleber, M.E.; Lahti, J.; Liu, Y.; Marques-Vidal, P.; Mellstrom, D.; Mooijaart, S.P.; Muller-Nurasyid, M.; Penninx, B.; Revez, J.A.; Rossing, P.; Raikkonen, K.; Sattar, N.; Scharnagl, H.; Sennblad, B.; Silveira, A.; St Pourcain, B.; Timpson, N.J.; Trollor, J.; Dongen, J. van; Heemst, D. van; Visvikis-Siest, S.; Vollenweider, P.; Volker, U.; Waldenberger, M.; Willemsen, G.; Zabaneh, D.; Morris, R.W.; Arnett, D.K.; Baune, B.T.; Boomsma, D.I.; Chang, Y.P.C.; Deary, I.J.; Deloukas, P.; Eriksson, J.G.; Evans, D.M.; Ferreira, M.A.; Gaunt, T.; Gudnason, V.; Hamsten, A.; Heinrich, J.; Hingorani, A.; Humphries, S.E.; Jukema, J.W.; Koenig, W.; Kumari, M.; Kutalik, Z.; Lawlor, D.A.; Lehtimaki, T.; Marz, W.; Mather, K.A.; Naitza, S.; Nauck, M.; Ohlsson, C.; Price, J.F.; Raitakari, O.; Rice, K.; Sachdev, P.S.; Slagboom, E.; Sorensen, T.I.A.; Spector, T.; Stacey, D.; Stathopoulou, M.G.; Tanaka, T.; Wannamethee, S.G.; Whincup, P.; Rotter, J.I.; Dehghan, A.; Boerwinkle, E.; Psaty, B.M.; Snieder, H.; Alizadeh, B.Z. & CHARGE Inflammation Working Grp (2021), Genome-wide association study of circulating interleukin 6 levels identifies novel loci, Human Molecular Genetics 30(5): 393-409.
- Wang, W.Y.; Dijk, K.W. van; Wijsman, C.A.; Rozing, M.P.; Mooijaart, S.P.; Beekman, M.; Slagboom, P.E.; Jukema, J.W.; Noordam, R. & Heemst, D. van (2021), Differential insulin sensitivity of NMR-based metabolomic measures in a two-step hyperinsulinemic euglycemic clamp study, Metabolomics 17(6).
- Chen, S.J.; Pawelec, G.; Trompet, S.; Goldeck, D.; Mortensen, L.H.; Slagboom, P.E.; Christensen, K.; Gussekloo, J.; Kearney, P.; Buckley, B.M.; Ford, I.; Jukema, J.W.; Westendorp, R.G.J. & Maier, A.B. (2021), Associations of cytomegalovirus infection with all-cause and cardiovascular mortality in multiple observational cohort studies of older adults, The Journal of Infectious Diseases 223(2): 238-246.
- Pellegrino-Coppola, D.; Claringbould, A.; Stutvoet, M.; Boomsma, D.I.; Ikram, M.A.; Slagboom, P.E.; Westra, H.J.; Franke, L. & BIOS Consortium (2021), Correction for both common and rare cell types in blood is important to identify genes that correlate with age, BMC Genomics 22(1).
- Rodriguez-Girondo, M.; Berg, N. van den; Hof, M.H.; Beekman, M. & Slagboom, E. (2021), Improved selection of participants in genetic longevity studies, BMC Medical Research Methodology 21(1).
- Bacalini, M.G.; Reale, A.; Malavolta, M.; Ciccarone, F.; Moreno-Villanueva, M.; Dolle, M.E.T.; Jansen, E.; Grune, T.; Gonos, E.S.; Schon, C.; Bernhardt, J.; Grubeck-Loebenstein, B.; Sikora, E.; Toussaint, O.; Debacq-Chainiaux, F.; Capri, M.; Hervonen, A.; Hurme, M.; Slagboom, P.E.; Breusing, N.; Aversano, V.; Tagliatesta, S.; Franceschi, C.; Blasco, M.A.; Burkle, A.; Caiafa, P. & Zampieri, M. (2021), Ageing affects subtelomeric DNA methylation in blood cells from a large European population enrolled in the MARK-AGE study, Geroscience 43(3): 1283-1302.
- Liu J., Lahousse L., Nivard M.G., Bot M., Chen L.M., Klinken J.B. van, Thesing C.S., Beekman M., Akker E.B. van den, Slieker R.C., Waterham E., Kallen C.J.H. van der, Boer I. de, Li-Gao R.F., Vojinovic D., Amin N., Radjabzadeh D., Kraaij R., Alferink L.J.M., Murad S.D., Uitterlinden A.G., Willemsen G., Pool R., Milaneschi Y., Heemst D. van, Suchiman H.E.D., Rutters F., Elders P.J.M., Beulens J.W.J., Heijden A.A.W.A. van der, Greevenbroek M.M.J. van, Arts I.C.W., Onderwater G.L.J., Maagdenberg A.M.J.M. van den, Mook-Kanamori D.O., Hankemeier T., Terwindt G.M., Stehouwer C.D.A., Geleijnse J.M., 't Hart L.M., Slagboom P.E., Dijk K.W. van, Zhernakova A., Fu J.Y., Penninx B.W.J.H., Boomsma D.I., Demirkan A., Stricker B.H.C. & Duijn C.M. van (2020), Integration of epidemiologic, pharmacologic, genetic and gut microbiome data in a drug-metabolite atlas, Nature Medicine 26: 110-117.
- Pool R., Hagenbeek F.A., Hendriks A.M., Dongen J. van, Willemsen G., Geus E. de, Dijk K.W. van, Verhoeven A., Suchiman H.E., Beekman M., Slagboom P.E., Harms A.C., Hankemeier T., Boomsma D.I., Beekman M., Suchiman H.E.D., Amin N., Beulens J.W., Bom J.A. van der, Bomer N., Demirkan A., Hilten J.A., Meessen J.M.T.A., Pool R., Moed M.H., Fu J., Onderwater G.L.J., Rutters F., So-Osman C., Flier W.M. van der, Heijden A.A.W.A. van der, Spek A. van der, Asselbergs F.W., Boersma E., Elders P.M., Geleijnse J.M., Ikram M.A., Kloppenburg M., Meulenbelt I., Mooijaart S.P., Nelissen R.G.H.H., Netea M.G., Penninx B.W.J.H., Stehouwer C.D.A., Teunissen C.E., Terwindt G.M., Hart L.M. 't, Maagdenberg A.M.J.M. van den, Harst P. van der, Horst I.C.C. van der, Kallen C.J.H. van der, Greevenbroek M.M.J. van, Spil W.E. van, Wijmenga C., Zwinderman A.H., Zhernikova A., Jukema J.W., Wolf J.J.H.B., Cats D., Mei H., Slofstra M., Swertz M., Akker E.B. van den, Deelen J., Reinders M.J.T., Boomsma D.I., Duijn C.M. van & Slagboom P.E. (2020), Genetics and not shared environment explains familial resemblance in adult metabolomics data, Twin Research and Human Genetics 23(3): 145-155.
- Liu, J.; Lahousse, L.; Nivard, M.G.; Bot, M.; Chen, L.M.; Klinken, J.B. van; Thesing, C.S.; Beekman, M.; Akker, E.B. van den; Slieker, R.C.; Waterham, E.; Kallen, C.J.H. van der; Boer, I. de; Li-Gao, R.F.; Vojinovic, D.; Amin, N.; Radjabzadeh, D.; Kraaij, R.; Alferink, L.J.M.; Murad, S.D.; Uitterlinden, A.G.; Willemsen, G.; Pool, R.; Milaneschi, Y.; Heemst, D. van; Suchiman, H.E.D.; Rutters, F.; Elders, P.J.M.; Beulens, J.W.J.; Heijden, A.A.W.A. van der; Greevenbroek, M.M.J. van; Arts, I.C.W.; Onderwater, G.L.J.; Maagdenberg, A.M.J.M. van den; Mook-Kanamori, D.O.; Hankemeier, T.; Terwindt, G.M.; Stehouwer, C.D.A.; Geleijnse, J.M.; Hart, L.M. 't; Slagboom, P.E.; Dijk, K.W. van; Zhernakova, A.; Fu, J.Y.; Penninx, B.W.J.H.; Boomsma, D.I.; Demirkan, A.; Stricker, B.H.C. & Duijn, C.M. van (2020), Integration of epidemiologic, pharmacologic, genetic and gut microbiome data in a drug-metabolite atlas, Nature Medicine 26(1): 110-+.
- Ouwens, K.G.; Jansen, R.; Nivard, M.G.; Dongen, J. van; Frieser, M.J.; Hottenga, J.J.; Arindrarto, W.; Claringbould, A.; Iterson, M. van; Mei, H.L.; Franke, L.; Heijmans, B.T.; Hoen, P.A.C. 't; Meurs, J. van; Brooks, A.I.; Penninx, B.W.J.H.; Boomsma, D.I.; Isaacs, A.; Pool, R.; Hottenga, J.J.; Greevenbroek, M.M.J. van; Stehouwer, C.D.A.; Kallen, C.J.H. van der; Schalkwijk, C.G.; Wijmenga, C.; Zhernakova, S.; Tigchelaar, E.F.; Slagboom, P.E.; Beekman, M.; Deelen, J.; Heemst, D. van; Veldink, J.H.; Berg, L.H. van den; Duijn, C.M. van; Hofman, B.A.; Uitterlinden, A.G.; Jhamai, P.M.; Verbiest, M.; Suchiman, H.E.D.; Verkerk, M.; Breggen, R. van der; Rooij, J. van; Lakenberg, N.; Galen, M. van; Bot, J.; Zhernakova, D.V.; van't Hof, P.; Deelen, P.; Nooren, I.; Moed, M.; Vermaat, M.; Luijk, R.; Bonder, M.J.; Dijk, F. van; Kielbasa, S.M.; Swertz, M.A.; Zwet, E.W. van; Hoen, P.B. 't & BIOS Consortium (2020), A characterization of cis- and trans-heritability of RNA-Seq-based gene expression, European Journal of Human Genetics 28(2): 253-263.
- Meessen, J.M.T.A.; Saberi-Hosnijeh, F.; Bomer, N.; Hollander, W. den; Bom, J.G. van der; Hilten, J.A. van; Spil, W.E. van; So-Osman, C.; Uitterlinden, A.G.; Kloppenburg, M.; Nelissen, R.G.H.H.; Duijn, C.M. van; Slagboom, P.E.; Meurs, J.B.J. van & Meulenbelt, I. (2020), Serum fatty acid chain length associates with prevalent symptomatic end-stage osteoarthritis, independent of BMI, Scientific Reports 10(1).
- Bot, M.; Milaneschi, Y.; Al-Shehri, T.; Amin, N.; Garmaeva, S.; Onderwater, G.L.J.; Pool, R.; Thesing, C.S.; Vijfhuizen, L.S.; Vogelzangs, N.; Arts, I.C.W.; Demirkan, A.; Duijn, C. van; Greevenbroek, M. van; Kallen, C.J.H. van der; Kohler, S.; Ligthart, L.; Maagdenberg, M.J.M. van den; Mook-Kanamori, D.O.; Mutsert, R. de; Tiemeier, H.; Schram, M.T.; Stehouwer, C.D.A.; Terwindt, G.M.; Dijk, K.W. van; Fu, J.Y.; Zhernakova, A.; Beekman, M.; Slagboom, P.E.; Boomsma, D.I.; Penninx, B.W.J.H. & BBMRI-NL Metabol Consortium (2020), Metabolomics profile in depression, Biological Psychiatry 87(5): 409-418.
- Bos, M.M.; Noordam, R.; Bennett, K.; Beekman, M.; Mook-Kanamori, D.O.; Dijk, K.W. van; Slagboom, P.E.; Lundstedt, T.; Surowiec, I. & Heemst, D. van (2020), Metabolomics analyses in non-diabetic middle-aged individuals reveal metabolites impacting early glucose disturbances and insulin sensitivity, Metabolomics 16(3).
- Berg, N. van den; Rodriguez-Girondo, M.; Mandemakers, K.; Janssens, A.A.P.O.; Beekman, M. & Slagboom, P.E. (2020), Longevity relatives count score identifies heritable longevity carriers and suggests case improvement in genetic studies, Aging Cell 19(6).
- Beekman, M.; Schutte, B.A.M.; Akker, E.B. van den; Noordam, R.; Dibbets-Schneider, P.; Geus-Oei, L.F. de; Deelen, J.; Rest, O.V. van de; Heemst, D. van; Feskens, E.J.M. & Slagboom, P.E. (2020), Lifestyle-intervention-induced reduction of abdominal fat is reflected by a decreased circulating glycerol level and an increased HDL diameter, Molecular Nutrition & Food Research 64(10).
- Spoel, E. van der; Roelfsema, F.; Akintola, A.A.; Jansen, S.W.; Slagboom, P.E.; Westendorp, R.G.J.; Blauw, G.J.; Pijl, H. & Heemst, D. van (2020), Interrelationships between pituitary hormones as assessed from 24-hour serum concentrations in healthy older subjects, The Journal of Clinical Endocrinology & Metabolism 105(4).
- Hagenbeek, F.A.; Pool, R.; Dongen, J. van; Draisma, H.H.M.; Hottenga, J.J.; Willemsen, G.; Abdellaoui, A.; Fedko, I.O.; Braber, A. den; Visser, P.J.; Geus, E.J.C.N. de; Dijk, K.W. van; Verhoeven, A.; Suchiman, H.E.; Beekman, M.; Slagboom, P.E.; Duijn, C.M. van; Harms, A.C.; Hankemeier, T.; Bartels, M.; Nivard, M.G.; Boomsma, D.I.; Wolf, J.J.H.B.; Cats, D.; Amin, N.; Beulens, J.W.; Bom, J.A. van der; Bomer, N.; Demirkan, A.; Hilten, J.A. van; Meessen, J.M.T.A.; Moed, M.H.; Fu, J.; Onderwater, G.L.J.; Rutters, F.; So-Osman, C.; Flier, W.M. van der; Heijden, A.A.W.A. van der; Spek, A. van der; Asselbergs, F.W.; Boersma, E.; Elders, P.M.; Geleijnse, J.M.; Ikram, M.A.; Kloppenburg, M.; Meulenbelt, I.; Mooijaart, S.P.; Nelissen, R.G.H.H.; Netea, M.G.; Penninx, B.W.J.H.; Stehouwer, C.D.A.; Teunissen, C.E.; Terwindt, G.M.; Hart, L.M. 't; Maagdenberg, A.M.J.M. van den; Harst, P. van der; Horst, I.C.C. van der; Kallen, C.J.H. van der; Greevenbroek, M.M.J. van; Spil, W.E. van; Wijmenga, C.; Zwinderman, A.H.; Zhernikova, A.; Jukema, J.W.; Mei, H.; Slofstra, M.; Swertz, M.; Akker, E.B. van den; Deelen, J.; Reinders, M.J.T. & BBMRI Metabolomics Consortium (2020), Heritability estimates for 361 blood metabolites across 40 genome-wide association studies, Nature Communications 11(1).
- Berg, N. van den; Dijk, I.K. van; Mourits, R.J.; Slagboom, P.E.; Janssens, A.A.P.O. & Mandemakers, K. (2020), Families in comparison, Population Studies 75(1).
- Raz, Y.; Akker, E.B. van den; Roest, T.; Riaz, M.; Rest, O. van de; Suchiman, H.E.D.; Lakenberg, N.; Stassen, S.A.; Putten, M. van; Feskens, E.J.M.; Reinders, M.J.T.; Goeman, J.; Beekman, M.; Raz, V. & Slagboom, P.E. (2020), A data-driven methodology reveals novel myofiber clusters in older human muscles, FASEB Journal 34(4): 5525-5537.
- Sijp, M.P.L. van der; Suchiman, H.E.D.; Eijk, M.; Vojinovic, D.; Niggebrugge, A.H.P.; Blauw, G.J.; Achterberg, W.P. & Slagboom, P.E. (2020), The prognostic value of metabolic profiling in older patients with a proximal femoral fracture, Geriatric Orthopaedic Surgery and Rehabilitation 11.
- Benedetti, E.; Gerstner, N.; Pucic-Bakovic, M.; Keser, T.; Reiding, K.R.; Ruhaak, L.R.; Stambuk, T.; Selman, M.H.J.; Rudan, I.; Polasek, O.; Hayward, C.; Beekman, M.; Slagboom, E.; Wuhrer, M.; Dunlop, M.G.; Lauc, G. & Krumsiek, J. (2020), Systematic evaluation of normalization methods for glycomics data based on performance of network inference, Metabolites 10(7).
- Tilburg, J.; Slieker, R.C.; Suchiman, H.E.D.; Heath, A.; Heemst, D. van; Slagboom, P.E.; Gruijl, F.R. de; Gunn, D.A. & Heijmans, B.T. (2020), Repeat UVA exposure of human skin fibroblasts induces both a transitionary and recovery DNA methylation response, Epigenomics 12(7): 563-573.
- Giacconi, R.; Maggi, F.; Macera, L.; Spezia, P.G.; Pistello, M.; Provinciali, M.; Piacenza, F.; Basso, A.; Burkle, A.; Moreno-Villanueva, M.; Dolle, M.E.T.; Jansen, E.; Grune, T.; Stuetz, W.; Gonos, E.S.; Schon, C.; Bernhardt, J.; Grubeck-Loebenstein, B.; Sikora, E.; Dudkowska, M.; Janiszewska, D.; Toussaint, O.; Debacq-Chainiaux, F.; Franceschi, C.; Capri, M.; Hervonen, A.; Hurme, M.; Slagboom, E.; Breusing, N.; Mocchegiani, E. & Malavolta, M. (2020), Prevalence and loads of torquetenovirus in the European MARK-AGE study population, The Journals of Gerontology, Series A: Biological Sciences and Medical Sciences 75(10): 1838-1845.
- Akker, E.B. van den; Trompet, S.; Wolf, J.J.H.B.; Beekman, M.; Suchiman, H.E.D.; Deelen, J.; Asselbergs, F.W.; Boersma, E.; Cats, D.; Elders, P.M.; Geleijnse, J.M.; Ikram, M.A.; Kloppenburg, M.; Mei, H.; Meulenbelt, I.; Mooijaart, S.P.; Nelissen, R.G.H.H.; Netea, M.G.; Penninx, B.W.J.H.; Slofstra, M.; Stehouwer, C.D.A.; Swertz, M.A.; Teunissen, C.E.; Terwindt, G.M.; Hart, L.M. 't; Maagdenberg, A.M.J.M. van den; Harst, P. van der; Horst, I.C.C. van der; Kallen, C.J.H. van der; Greevenbroek, M.M.J. van; Spil, W.E. van; Wijmenga, C.; Zhernakova, A.; Zwinderman, A.H.; Sattar, N.; Jukema, J.W.; Duijn, C.M. van; Boomsma, D.I.; Reinders, M.J.T. & Slagboom, P.E. (2020), Metabolic age based on the BBMRI-NL H-1-NMR metabolomics repository as biomarker of age-related disease, Circulation: Genomic and Precision Medicine 13(5): 541-547.
- Mourits, R.J.; Berg, N. van den; Rodriguez-Girondo, M.; Mandemakers, K.; Slagboom, P.E.; Beekman, M. & Janssens, A.A.P.O. (2020), Intergenerational transmission of longevity is not affected by other familial factors, The History of the Family 25(3): 484-526.
- Hop, P.J.; Luijk, R.; Daxinger, L.; Iterson, M. van; Dekkers, K.F.; Jansen, R.; Meurs, J.B.J. van; Hoen, P.A.C. 't; Ikram, M.A.; Greevenbroek, M.M.J. van; Boomsma, D.I.; Slagboom, P.E.; Veldink, J.H.; Zwet, E.W. van; Heijmans, B.T. & BIOS Consortium (2020), Genome-wide identification of genes regulating DNA methylation using genetic anchors for causal inference, Genome Biology 21(1).
- Pool, R.; Hagenbeek, F.A.; Hendriks, A.M.; Dongen, J. van; Willemsen, G.; Geus, E. de; Dijk, K.W. van; Verhoeven, A.; Suchiman, H.E.; Beekman, M.; Slagboom, P.E.; Harms, A.C.; Hankemeier, T.; Boomsma, D.I.; Beekman, M.; Suchiman, H.E.D.; Amin, N.; Beulens, J.W.; Bom, J.A. van der; Bomer, N.; Demirkan, A.; Hilten, J.A. van; Meessen, J.M.T.A.; Pool, R.; Moed, M.H.; Fu, J.; Onderwater, G.L.J.; Rutters, F.; So-Osman, C.; Flier, W.M. van der; Heijden, A.A.W.A. van der; Spek, A. van der; Asselbergs, F.W.; Boersma, E.; Elders, P.M.; Geleijnse, J.M.; Ikram, M.A.; Kloppenburg, M.; Meulenbelt, I.; Mooijaart, S.P.; Nelissen, R.G.H.H.; Netea, M.G.; Penninx, B.W.J.H.; Stehouwer, C.D.A.; Teunissen, C.E.; Terwindt, G.M.; Hart, L.M. 't; Maagdenberg, A.M.J.M. van den; Harst, P. van der; Horst, I.C.C. van der; Kallen, C.J.H. van der; Greevenbroek, M.M.J. van; Spil, W.E. van; Wijmenga, C.; Zwinderman, A.H.; Zhernikova, A.; Jukema, J.W.; Wolf, J.J.H.B.; Cats, D.; Mei, H.; Slofstra, M.; Swertz, M.; Akker, E.B. van den; Deelen, J.; Reinders, M.J.T.; Boomsma, D.I.; Duijn, C.M. van; Slagboom, P.E. & BBMRI Metabol Consortium (2020), Genetics and not shared environment explains familial resemblance in adult metabolomics data, Twin Research and Human Genetics 23(3): 145-155.
- Akker, E.B. van den; Makrodimitris, S.; Hulsman, M.; Brugman, M.H.; Nikolic, T.; Bradley, T.; Waisfisz, Q.; Baas, F.; Jakobs, M.E.; Jong, D. de; Slagboom, P.E.; Staal, F.J.T.; Reinders, M.J.T. & Holstege, H. (2020), Dynamic clonal hematopoiesis and functional T-cell immunity in a supercentenarian, Leukemia 35.
- Rutten, J.W.; Hack, R.J.; Duering, M.; Gravesteijn, G.; Dauwerse, J.G.; Overzier, M.; Akker, E.B. van den; Slagboom, E.; Holstege, H.; Nho, K.; Saykin, A.; Dichgans, M.; Malik, R. & Oberstein, S.A.J.L. (2020), Broad phenotype of cysteine-altering NOTCH3 variants in UK Biobank CADASIL to nonpenetrance, Neurology 95(13): E1835-E1843.
- Klaric, L.; Tsepilov, Y.A.; Stanton, C.M.; Mangino, M.; Sikka, T.T.; Esko, T.; Pakhomov, E.; Salo, P.; Deelen, J.; McGurnaghan, S.J.; Keser, T.; Vuckovic, F.; Ugrina, I.; Kristic, J.; Gudelj, I.; Stambuk, J.; Plomp, R.; Pucic-Bakovic, M.; Pavic, T.; Vilaj, M.; Trbojevic-Akmacic, I.; Drake, C.; Dobrinic, P.; Mlinarec, J.; Jelusic, B.; Richmond, A.; Timofeeva, M.; Grishchenko, A.K.; Dmitrieva, J.; Bermingham, M.L.; Sharapov, S.Z.; Farrington, S.M.; Theodoratou, E.; Uh, H.W.; Beekman, M.; Slagboom, E.P.; Louis, E.; Georges, M.; Wuhrer, M.; Colhoun, H.M.; Dunlop, M.G.; Perola, M.; Fischer, K.; Polasek, O.; Campbell, H.; Rudan, I.; Wilson, J.F.; Zoldos, V.; Vitart, V.; Spector, T.; Aulchenko, Y.S.; Lauc, G. & Hayward, C. (2020), Glycosylation of immunoglobulin G is regulated by a large network of genes pleiotropic with inflammatory diseases, Science Advances 6(8).
- Li, C.; Stoma, S.; Lotta, L.A.; Warner, S.; Albrecht, E.; Allione, A.; Arp, P.P.; Broer, L.; Buxton, J.L.; Alves, A.D.C.; Deelen, J.; Fedko, I.O.; Gordon, S.D.; Jiang, T.; Karlsson, R.; Kerrison, N.; Loe, T.K.; Mangino, M.; Milaneschi, Y.; Miraglio, B.; Pervjakova, N.; Russo, A.; Surakka, I.; Spek, A. van der; Verhoeven, J.E.; Amin, N.; Beekman, M.; Blakemore, A.I.; Canzian, F.; Hamby, S.E.; Hottenga, J.J.; Jones, P.D.; Jousilahti, P.; Magi, R.; Medland, S.E.; Montgomery, G.W.; Nyholt, D.R.; Perola, M.; Pietilainen, K.H.; Salomaa, V.; Sillanpaa, E.; Suchiman, H.E.; Heemst, D. van; Willemsen, G.; Agudo, A.; Boeing, H.; Boomsma, D.I.; Chirlaque, M.D.; Fagherazzi, G.; Ferrari, P.; Franks, P.; Gieger, C.; Eriksson, J.G.; Gunter, M.; Hagg, S.; Hovatta, I.; Imaz, L.; Kaprio, J.; Kaaks, R.; Key, T.; Krogh, V.; Martin, N.G.; Melander, O.; Metspalu, A.; Moreno, C.; Onland-Moret, N.C.; Nilsson, P.; Ong, K.K.; Overvad, K.; Palli, D.; Panico, S.; Pedersen, N.L.; Penninx, B.W.J.H.; Quiros, J.R.; Jarvelin, M.R.; Rodriguez-Barranco, M.; Scott, R.A.; Severi, G.; Slagboom, P.E.; Spector, T.D.; Tjonneland, A.; Trichopoulou, A.; Tumino, R.; Uitterlinden, A.G.; Schouw, Y.T. van der; Duijn, C.M. van; Weiderpass, E.; Denchi, E.L.; Matullo, G.; Butterworth, A.S.; Danesh, J.; Samani, N.J.; Wareham, N.J.; Nelson, C.P.; Langenberg, C. & Codd, V. (2020), Genome-wide association analysis in humans links nucleotide metabolism to leukocyte telomere length, American Journal of Human Genetics 106(3): 389-404.
- Sargurupremraj, M.; Suzuki, H.; Jian, X.Q.; Sarnowski, C.; Evans, T.E.; Bis, J.C.; Eiriksdottir, G.; Sakaue, S.; Terzikhan, N.; Habes, M.; Zhao, W.; Armstrong, N.J.; Hofer, E.; Yanek, L.R.; Hagenaars, S.P.; Kumar, R.B.; Akker, E.B. van den; McWhirter, R.E.; Trompet, S.; Mishra, A.; Saba, Y.; Satizabal, C.L.; Beaudet, G.; Petit, L.; Tsuchida, A.; Zago, L.; Schilling, S.; Sigurdsson, S.; Gottesman, R.F.; Lewis, C.E.; Aggarwal, N.T.; Lopez, O.L.; Smith, J.A.; Hernandez, M.C.V.; Grond, J. van der; Wright, M.J.; Knol, M.J.; Dorr, M.; Thomson, R.J.; Bordes, C.; Grand, Q. le; Duperron, M.G.; Smith, A.V.; Knopman, D.S.; Schreiner, P.J.; Evans, D.A.; Rotter, J.I.; Beiser, A.S.; Maniega, S.M.; Beekman, M.; Trollor, J.; Stott, D.J.; Vernooij, M.W.; Wittfeld, K.; Niessen, W.J.; Soumare, A.; Boerwinkle, E.; Sidney, S.; Turner, S.T.; Davies, G.; Thalamuthu, A.; Volker, U.; Buchem, M.A. van; Bryan, R.N.; Dupuis, J.; Bastin, M.E.; Ames, D.; Teumer, A.; Amouyel, P.; Kwok, J.B.; Bulow, R.; Deary, I.J.; Schofield, P.R.; Brodaty, H.; Jiang, J.Y.; Tabara, Y.; Setoh, K.; Miyamoto, S.; Yoshida, K.; Nagata, M.; Kamatani, Y.; Matsuda, F.; Psaty, B.M.; Bennett, D.A.; Jager, P.L. de; Mosley, T.H.; Sachdev, P.S.; Schmidt, R.; Warren, H.R.; Evangelou, E.; Tregouet, D.A.; Ikram, M.A.; Wen, W.; DeCarli, C.; Srikanth, V.K.; Jukema, J.W.; Slagboom, E.P.; Kardia, S.L.R.; Okada, Y.; Mazoyer, B.; Wardlaw, J.M.; Nyquist, P.A.; Mather, K.A.; Grabe, H.J.; Schmidt, H.; Duijn, C.M. van; Gudnason, V.; Longstreth, W.T.; Launer, L.J.; Lathrop, M.; Seshadri, S.; Tzourio, C.; Adams, H.H.; Matthews, P.M.; Fornage, M.; Debette, S.; Int Network Thrombosis INVENT Cons & Int Headache Genomics Consortium I (2020), Cerebral small vessel disease genomics and its implications across the lifespan, Nature Communications 11(1).
- Beenakker, K.G.M.; Westendorp, R.G.J.; Craen, A.J.M. de; Chen, S.J.; Raz, Y.; Ballieux, B.E.P.B.; Nelissen, R.G.H.H.; Later, A.F.L.; Huizinga, T.W.; Slagboom, P.E.; Boomsma, D.I. & Maier, A.B. (2020), Men have a stronger monocyte-derived cytokine production response upon stimulation with the gram-negative stimulus lipopolysaccharide than women, Journal of Innate Immunity 12(2): 142-153.
- Meessen, J.M.T.A.; Fiocco, M.; Tordoir, R.L.; Sjer, A.; Verdegaal, S.H.M.; Slagboom, P.E.; Vlieland, T.P.M.V. & Nelissen, R.G.H.H. (2020), Association of handgrip strength with patient-reported outcome measures after total hip and knee arthroplasty, Rheumatology International 40(4): 565-571.
- Knol, M.J.; Lu, D.W.; Traylor, M.; Adams, H.H.H.; Romero, J.R.J.; Smith, A.V.; Fornage, M.; Hofer, E.; Liu, J.F.; Hostettler, I.C.; Luciano, M.; Trompet, S.; Giese, A.K.; Hilal, S.; Akker, E.B. van den; Vojinovic, D.; Li, S.; Sigurdsson, S.; Lee, S.J. van der; Jack, C.R.; Wilson, D.; Yilmaz, P.; Satizabal, C.L.; Liewald, D.C.M.; Grond, J. van der; Chen, C.; Saba, Y.; Lugt, A. van der; Bastin, M.E.; Windham, B.G.; Cheng, C.Y.; Pirpamer, L.; Kantarci, K.; Himali, J.J.; Yang, Q.; Morris, Z.; Beiser, A.S.; Tozer, D.J.; Vernooij, M.W.; Amin, N.; Beekman, M.; Koh, J.Y.; Stott, D.J.; Houlden, H.; Schmidt, R.; Gottesman, R.F.; MacKinnon, A.D.; DeCarli, C.; Gudnason, V.; Deary, I.J.; Duijn, C.M. van; Slagboom, P.E.; Wong, T.Y.; Rost, N.S.; Jukema, J.W.; Mosley, T.H.; Werring, D.J.; Schmidt, H.; Wardlaw, J.M.; Ikram, M.A.; Seshadri, S.; Launer, L.J. & Markus, H.S. (2020), Association of common genetic variants with brain microbleeds, Neurology 95(24): E3331-E3343.
- Bos, M.M.; Vliet, N.A. van; Beekman, M.; Slagboom, P.E.; Vernooij, M.; Grond, J. van der; Lugt, A. van der; Ahmadizar, F.; Ghanbari, M.; Ikram, M.A.; Heemst, D. van; Bos, D.; Kavousi, M. & BBMRI Metabolomics Consortium (2020), Circulating levels of metabolic biomarkers of site-specific and sex-specific arterial calcification in the multi-cohort BBMRI setting, European Heart Journal 41: 1339-1339.
- Paraschiakos, S.; Cachucho, R.; Moed, M.; Heemst, D. van; Mooijaart, S.; Slagboom, E.P.; Knobbe, A. & Beekman, M. (2020), Activity recognition using wearable sensors for tracking the elderly, User Modeling and User-Adapted Interaction 30.
- Boomsma D., Pool R., Hagenbeek F., Hankemeier T., Kluft C., Fanos V., Nivard M., Bartels M., Harms A.C. & Slagboom P. (2019), Twin studies of metabolomics traits and metabo-phenotype associations, Behavior Genetics 49(6): 494.
- Lee S.J. van der, Teunissen C.E., Pool R., Shipley M.J., Teumer A., Chouraki V., Lent D.M. van, Tynkkynen J., Fischer K., Hernesniemi J., Haller T., Singh-Manoux A., Verhoeven A., Willemsen G., Leeuw F.A. de, Wagner H., Dongen J. van, Hertel J., Budde K., Dijk K. Willems van, Weinhold L., Ikram M.A., Pietzner M., Perola M., Wagner M., Friedrich N., Slagboom P.E., Scheltens P., Yang Q., Gertzen R.E., Egert S., Li S., Hankemeier T., Beijsterveldt C.E.M. van, Vasan R.S., Maier W., Peeters C.F.W., Grabe H.J., Ramirez A., Seshadri S., Metspalu A., Kivimaki M., Salomaa V., Demirkan A., Boomsma D.I., Flier W.M. van der, Amin N. & Duijn C.M. van (2019), Erratum to "Circulating metabolites and general cognitive ability and dementia: Evidence from 11 cohort studies" [Alzheimer's & Dementia 2018;14:707-22.], Alzheimer's & Dementia 15(2): 319.
- Gardiner, S.L.; Trompet, S.; Sabayan, B.; Boogaard, M.W.; Jukema, J.W.; Slagboom, P.E.; Roos, R.A.C.; Grond, J. van der & Aziz, N.A. (2019), Repeat variations in polyglutamine disease-associated genes and cognitive function in old age, Neurobiology of Aging 84.
- Plaat, D. van der; Vonk, J.M.; Terzikhan, N.; Jong, K. de; Vries, M. de; Bastide-van Gemert, S. la; Diemen, C.C. van; Lahousse, L.; Brusselle, G.; Nedeljkovic, I.; Amin, N.; Kromhout, H.; Vermeulen, R.C.H.; Postma, D.S.; Duijn, C.M. van; Boezen, H.M.; Heijmans, B.T.; Hoen, P.A.C.T.; Meurs, J. van; Isaacs, A.; Jansen, R.; Franke, L.; Boomsma, D.I.; Pool, R.; Dongen, J. van; Hottenga, J.J.; Greevenbroek, M.M.J. van; Stehouwer, C.D.A.; Kallen, C.J.H. van der; Schalkwijk, C.G.; Wijmenga, C.; Zhernakova, S.; Tigchelaar, E.E.; Slagboom, P.E.; Beekman, M.; Deelen, J.; Heemst, D. van; Veldink, J.H.; Berg, L.H. van den; Hofman, B.A.; Uitterlinden, A.G.; Jhamai, P.M.; Verbiest, M.; Suchiman, H.E.D.; Verkerk, M.; Breggen, R. van der; Rooij, J. van; Lakenberg, N.; Mei, H.; Iterson, M. van; Galen, M. van; Bot, J.; Zhernakova, D.V.; Hof, P.V.; Deelen, P.; Nooren, I.; Moed, M.; Vermaat, M.; Luijk, R.; Bonder, M.J.; Dijk, F. van; Arindrarto, W.; Kielbasa, S.M.; Swertz, M.A.; Zwet, E.W. van; Hoen, P.B. 't & BIOS Consortium (2019), Occupational exposure to gases/fumes and mineral dust affect DNA methylation levels of genes regulating expression, Human Molecular Genetics 28(15): 2477-2485.
- Maas, S.C.E.; Vidaki, A.; Wilson, R.; Teumer, A.; Liu, F.; Meurs, J.B.J. van; Uitterlinden, A.G.; Boomsma, D.I.; Geus, E.J.C. de; Willemsen, G.; Dongen, J. van; Kallen, C.J.H. van der; Slagboom, P.E.; Beekman, M.; Heemst, D. van; Berg, L.H. van den; Duijts, L.; Jaddoe, V.W.V.; Ladwig, K.H.; Kunze, S.; Peters, A.; Ikram, M.A.; Grabe, H.J.; Felix, J.F.; Waldenberger, M.; Franco, O.H.; Ghanbari, M.; Kayser, M. & BIOS Consortium (2019), Validated inference of smoking habits from blood with a finite DNA methylation marker set, European Journal of Epidemiology 34(11): 1055-1074.
- Giacconi, R.; Malavolta, M.; Burkle, A.; Moreno-Villanueva, M.; Franceschi, C.; Capri, M.; Slagboom, P.E.; Jansen, E.H.J.M.; Dolle, M.E.T.; Grune, T.; Weber, D.; Hervonen, A.; Stuetz, W.; Breusing, N.; Ciccarone, F.; Zampieri, M.; Aversano, V.; Caiafa, P.; Formentini, L.; Piacenza, F.; Pierpaoli, E.; Basso, A.; Provinciali, M. & Cardelli, M. (2019), Nutritional Factors Modulating Alu Methylation in an Italian Sample from The Mark-Age Study Including Offspring of Healthy Nonagenarians, Nutrients 11(12).
- Victorelli, S.; Lagnado, A.; Halim, J.; Moore, W.; Talbot, D.; Barrett, K.; Chapman, J.; Birch, J.; Ogrodnik, M.; Meves, A.; Pawlikowski, J.S.; Jurk, D.; Adams, P.D.; Heemst, D. van; Beekman, M.; Slagboom, P.E.; Gunn, D.A. & Passos, J.F. (2019), Senescent human melanocytes drive skin ageing via paracrine telomere dysfunction, EMBO Journal 38(23).
- Bos, M.M.; Noordam, R.; Blauw, G.J.; Slagboom, P.E.; Rensen, P.C.N. & Heemst, D. van (2019), The ApoE e4 Isoform: Can the Risk of Diseases be Reduced by Environmental Factors?, Journals of Gerontology, Series A 74(1): 99-107.
- Davies, G.; Lam, M.; Harris, S.E.; Trampush, J.W.; Luciano, M.; Hill, W.D.; Hagenaars, S.P.; Ritchie, S.J.; Marioni, R.E.; Fawns-Ritchie, C.; Liewald, D.C.M.; Okely, J.A.; Ahola-Olli, A.V.; Barnes, C.L.K.; Bertram, L.; Bis, J.C.; Burdick, K.E.; Christoforou, A.; DeRosse, P.; Djurovic, S.; Espeseth, T.; Giakoumaki, S.; Giddaluru, S.; Gustavson, D.E.; Hayward, C.; Hofer, E.; Ikram, M.A.; Karlsson, R.; Knowles, E.; Lahti, J.; Leber, M.; Li, S.; Mather, K.A.; Melle, I.; Morris, D.; Oldmeadow, C.; Palviainen, T.; Payton, A.; Pazoki, R.; Petrovic, K.; Reynolds, C.A.; Sargurupremraj, M.; Scholz, M.; Smith, J.A.; Smith, A.V.; Terzikhan, N.; Thalamuthu, A.; Trompet, S.; Lee, S.J. van der; Ware, E.B.; Windham, B.G.; Wright, M.J.; Yang, J.Y.; Yu, J.; Ames, D.; Amin, N.; Amouyel, P.; Andreassen, O.A.; Armstrong, N.J.; Assareh, A.A.; Attia, J.R.; Attix, D.; Avramopoulos, D.; Bennett, D.A.; Bohmer, A.C.; Boyle, P.A.; Brodaty, H.; Campbell, H.; Cannon, T.D.; Cirulli, E.T.; Congdon, E.; Conley, E.D.; Corley, J.; Cox, S.R.; Dale, A.M.; Dehghan, A.; Dick, D.; Dickinson, D.; Eriksson, J.G.; Evangelou, E.; Faul, J.D.; Ford, I.; Freimer, N.A.; Gao, H.; Giegling, I.; Gillespie, N.A.; Gordon, S.D.; Gottesman, R.F.; Griswold, M.E.; Gudnason, V.; Harris, T.B.; Hartmann, A.M.; Hatzimanolis, A.; Heiss, G.; Holliday, E.G.; Joshi, P.K.; Kahonen, M.; Kardia, S.L.R.; Karlsson, I.; Kleineidam, L.; Knopman, D.S.; Kochan, N.A.; Konte, B.; Kwok, J.B.; Hellard, S. le; Lee, T.; Lehtimaki, T.; Li, S.C.; Lill, C.M.; Liu, T.; Koini, M.; London, E.; Longstreth, W.T.; Lopez, O.L.; Loukola, A.; Luck, T.; Lundervold, A.J.; Lundquist, A.; Lyytikainen, L.P.; Martin, N.G.; Montgomery, G.W.; Murray, A.D.; Need, A.C.; Noordam, R.; Nyberg, L.; Ollier, W.; Papenberg, G.; Pattie, A.; Polasek, O.; Poldrack, R.A.; Psaty, B.M.; Reppermund, S.; Riedel-Heller, S.G.; Rose, R.J.; Rotter, J.I.; Roussos, P.; Rovio, S.P.; Saba, Y.; Sabb, F.W.; Sachdev, P.S.; Satizabal, C.L.; Schmid, M.; Scott, R.J.; Scult, M.A.; Simino, J.; Slagboom, P.E.; Smyrnis, N.; Soumare, A.; Stefanis, N.C.; Stott, D.J.; Straub, R.E.; Sundet, K.; Taylor, A.M.; Taylor, K.D.; Tzoulaki, I.; Tzourio, C.; Uitterlinden, A.; Vitart, V.; Voineskos, A.N.; Kaprio, J.; Wagner, M.; Wagner, H.; Weinhold, L.; Wen, K.H.; Widen, E.; Yang, Q.; Zhao, W.; Adams, H.H.H.; Arking, D.E.; Bilder, R.M.; Bitsios, P.; Boerwinkle, E.; Chiba-Falek, O.; Corvin, A.; Jager, P.L. de; Debette, S.; Donohoe, G.; Elliott, P.; Fitzpatrick, A.L.; Gill, M.; Glahn, D.C.; Hagg, S.; Hansell, N.K.; Hariri, A.R.; Ikram, M.K.; Jukema, J.W.; Vuoksimaa, E.; Keller, M.C.; Kremen, W.S.; Launer, L.; Lindenberger, U.; Palotie, A.; Pedersen, N.L.; Pendleton, N.; Porteous, D.J.; Raikkonen, K.; Raitakari, O.T.; Ramirez, A.; Reinvang, I.; Rudan, I.; Rujescu, D.; Schmidt, R.; Schmidt, H.; Schofield, P.W.; Schofield, P.R.; Starr, J.M.; Steen, V.M.; Trollor, J.N.; Turner, S.T.; Duijn, C.M. van; Villringer, A.; Weinberger, D.R.; Weir, D.R.; Wilson, J.F.; Malhotra, A.; McIntosh, A.M.; Gale, C.R.; Seshadri, S.; Mosley, T.H.; Bressler, J.; Lencz, T. & Deary, I.J. (2019), Study of 300,486 individuals identifies 148 independent genetic loci influencing general cognitive function (vol 9, 2098, 2018), Nature Communications 10.
- Almeida, R.C. de; Ramos, Y.F.M.; Mahfouz, A.; Hollander, W. den; Lakenberg, N.; Houtman, E.; Hoolwerff, M. van; Suchiman, H.E.D.; Ruiz, A.R.; Slagboom, P.E.; Mei, H.L.; Kielbasa, S.M.; Nelissen, R.G.H.H.; Reinders, M. & Meulenbelt, I. (2019), RNA sequencing data integration reveals an miRNA interactome of osteoarthritis cartilage, Annals of the Rheumatic Diseases 78(2): 270-277.
- Onderwater, G.L.J.; Ligthart, L.; Bot, M.; Demirkan, A.; Fu, J.Y.; Kallen, C.J.H. van der; Vijfhuizen, L.S.; Pool, R.; Liu, J.; Vanmolkot, F.H.M.; Beekman, M.; Wen, K.X.; Amin, N.; Thesing, C.S.; Pijpers, J.A.; Kies, D.A.; Zielman, R.; Boer, I. de; Greevenbroek, M.M.J. van; Arts, I.C.W.; Milaneschi, Y.; Schram, M.T.; Dagnelie, P.C.; Franke, L.; Ikram, M.A.; Ferrari, M.D.; Goeman, J.J.; Slagboom, P.E.; Wijmenga, C.; Stehouwer, C.D.A.; Boomsma, D.I.; Duijn, C.M. van; Penninx, B.W.; Hoen, P.A.C. 't; Terwindt, G.M.; Maagdenberg, A.M.J.M. van den & BBMRI Metabolomics Consortium (2019), Large-scale plasma metabolome analysis reveals alterations in HDL metabolism in migraine, Neurology 92(16): E1899-E1911.
- Victorelli, S.; Lagnado, A.; Halim, J.; Moore, W.; Talbot, D.; Barrett, K.; Chapman, J.; Birch, J.; Ogrodnik, M.; Meves, A.; Pawlikowski, J.S.; Jurk, D.; Adams, P.D.; Heemst, D. van; Beekman, M.; Slagboom, P.E.; Gunn, D.A. & Passos, J.F. (2019), Senescent human melanocytes drive skin ageing via paracrine telomere dysfunction, EMBO Journal.
- Boomsma D, Pool R, Hagenbeek F, Hankemeier T, Kluft C, Fanos V, Nivard M, Bartels M, Harms A & Slagboom E (2019), Twin studies of metabolomics traits and metabo-phenotype associations, Behavior Genetics 49(6): 494-494.
- Gardiner, S.L.; Mutsert, R. de; Trompet, S.; Boogaard, M.W.; Dijk, K.W. van; Jukema, P.J.W.; Slagboom, P.E.; Roos, R.A.C.; Pijl, H.; Rosendaal, F.R. & Aziz, N.A. (2019), Repeat length variations in polyglutamine disease-associated genes affect body mass index, International Journal of Obesity 43(3): 440-449.
- Nersisyan, L.; Nikoghosyan, M.; Francioli, L.C.; Menelaou, A.; Pulit, S.L.; Elbers, C.C.; Kloosterman, W.P.; Setten, J. van; Nijman, I.J.; Renkens, I.; Bakker, P.I.W. de; Dijk, F. van; Neerincx, P.B.T.; Deelen, P.; Kanterakis, A.; Dijkstra, M.; Byelas, H.; Velde, K.J. van der; Platteel, M.; Swertz, M.A.; Wijmenga, C.; Palamara, P.F.; Pe'er, I.; Ye, K.; Lameijer, E.W.; Moed, M.H.; Beekman, M.; Craen, A.J.M. de; Suchiman, H.E.D.; Slagboom, P.E.; Guryev, V.; Abdellaoui, A.; Hottenga, J.J.; Kattenberg, M.; Willemsen, G.; Boomsma, D.I.; Leeuwen, E.M. van; Karssen, L.C.; Amin, N.; Rivadeneira, F.; Isaacs, A.; Hofman, A.; Uitterlinden, A.G.; Duijn, C.M. van; Oven, M. van; Kayser, M.; Vermaat, M.; Laros, J.F.J.; Dunnen, J.T. den; Enckevort, D. van; Mei, H.L.; Li, M.K.; Stoneking, M.; Schaik, B.D.C. van; Bot, J.; Marschall, T.; Schonhuth, A.; Hehir-Kwa, J.Y.; Handsaker, R.E.; Polak, P.; Sohail, M.; Vuzman, D.; Estrada, K.; McCarroll, S.A.; Sunyaev, S.R.; Hormozdiari, F.; Koval, V.; Medina-Gomez, C.; Oostra, B.; Veldink, J.H.; Berg, L.H. van den; Pitts, S.J.; Potluri, S.; Sundar, P.; Cox, D.R.; Knijff, P. de; Li, Q.B.; Li, Y.R.; , Y.P. du; Chen, R.Y.; Cao, H.Z.; Wang, J.; Li, N.; Cao, S.J.; Bovenberg, J.A.; Ommen, G.J.B. van; Arakelyan, A. & Genome Netherlands Consortium (2019), WGS-based telomere length analysis in Dutch family trios implicates stronger maternal inheritance and a role for RRM1 gene, Scientific Reports 9.
- Spek, A. van der; Broer, L.; Draisma, H.H.M.; Pool, R.; Albrecht, E.; Beekman, M.; Mangino, M.; Raag, M.; Nyholt, D.R.; Dharuri, H.K.; Codd, V.; Amin, N.; Geus, E.J.C. de; Deelen, J.; Demirkan, A.; Yet, I.; Fischer, K.; Haller, T.; Henders, A.K.; Isaacs, A.; Medland, S.E.; Montgomery, G.W.; Mooijaart, S.P.; Strauch, K.; Suchiman, H.E.D.; Vaarhorst, A.A.M.; Heemst, D. van; Wang-Sattler, R.; Whitfield, J.B.; Willemsen, G.; Wright, M.J.; Martin, N.G.; Samani, N.J.; Metspalu, A.; Slagboom, P.E.; Spector, T.D.; Boomsma, D.I.; Duijn, C.M. van & Gieger, C. (2019), Metabolomics reveals a link between homocysteine and lipid metabolism and leukocyte telomere length: the ENGAGE consortium, Scientific Reports 9.
- Berg, N. van den; Rodriguez-Girondo, M.; Dijk, I.K. van; Mourits, R.J.; Mandemakers, K.; Janssens, A.A.P.O.; Beekman, M.; Smith, K.R. & Slagboom, P.E. (2019), Longevity defined as top 10% survivors and beyond is transmitted as a quantitative genetic trait, Nature Communications 10.
- Surowiec, I.; Noordam, R.; Bennett, K.; Beekman, M.; Slagboom, P.E.; Lundstedt, T. & Heemst, D. van (2019), Metabolomic and lipidomic assessment of the metabolic syndrome in Dutch middle-aged individuals reveals novel biological signatures separating health and disease, Metabolomics 15(2).
- Porcu, E.; Rueger, S.; Lepik, K.; Agbessi, M.; Ahsan, H.; Alves, I.; Andiappan, A.; Arindrarto, W.; Awadalla, P.; Battle, A.; Beutner, F.; Bonder, M.J.; Boomsma, D.; Christiansen, M.; Claringbould, A.; Deelen, P.; Esko, T.; Fave, M.J.; Franke, L.; Frayling, T.; Gharib, S.A.; Gibson, G.; Heijmans, B.T.; Hemani, G.; Jansen, R.; Kahonen, M.; Kalnapenkis, A.; Kasela, S.; Kettunen, J.; Kim, Y.; Kirsten, H.; Kovacs, P.; Krohn, K.; Kronberg-Guzman, J.; Kukushkina, V.; Lee, B.; Lehtimaki, T.; Loeffler, M.; Marigorta, U.M.; Mei, H.L.; Milani, L.; Montgomery, G.W.; Muller-Nurasyid, M.; Nauck, M.; Nivard, M.; Penninx, B.; Perola, M.; Pervjakova, N.; Pierce, B.L.; Powell, J.; Prokisch, H.; Psaty, B.M.; Raitakari, O.T.; Ripatti, S.; Rotzschke, O.; Saha, A.; Scholz, M.; Schramm, K.; Seppala, I.; Slagboom, E.P.; Stehouwer, C.D.A.; Stumvoll, M.; Sullivan, P.; Hoen, P.A.C. 't; Teumer, A.; Thiery, J.; Tong, L.; Tonjes, A.; Dongen, J. van; Iterson, M. van; Meurs, J. van; Veldink, J.H.; Verlouw, J.; Visscher, P.M.; Volker, U.; Vosa, U.; Westra, H.J.; Wijmenga, C.; Yaghootkar, H.; Yang, J.; Zeng, B.; Zhang, F.T.; Arindrarto, W.; Beekman, M.; Boomsma, D.I.; Bot, J.; Deelen, J.; Deelen, P.; Franke, L.; Heijmans, B.T.; Hofman, B.A.; Hottenga, J.J.; Isaacs, A.; Bonder, M.J.; Jhamai, P.M.; Jansen, R.; Kielbasa, S.M.; Lakenberg, N.; Luijk, R.; Mei, H.; Moed, M.; Nooren, I.; Pool, R.; Schalkwijk, C.G.; Slagboom, P.E.; Stehouwer, C.D.A.; Suchiman, H.E.D.; Swertz, M.A.; Tigchelaar, E.F.; Uitterlinden, A.G.; Berg, L.H. van den; Breggen, R. van der; Kallen, C.J.H. van der; Dijk, F. van; Dongen, J. van; Duijn, C.M. van; Galen, M. van; Greevenbroek, M.M.J. van; Heemst, D. van; Iterson, M. van; Meurs, J. van; Rooij, J. van; Van't Hof, P.; Zwet, E.W. van; Vermaat, M.; Veldink, J.H.; Verbiest, M.; Verkerk, M.; Wijmenga, C.; Zhernakova, D.V.; Zhernakova, S.; Santoni, F.A.; Reymond, A.; Kutalik, Z.; eQTLGen Consortium & BIOS Consortium (2019), Mendelian randomization integrating GWAS and eQTL data reveals genetic determinants of complex and clinical traits, Nature Communications 10.
- Onderwater, G.L.J.; Ligthart, L.; Bot, M.; Demirkan, A.; Fu, J.Y.; Kallen, C.J.H. van der; Vijfhuizen, L.S.; Pool, R.; Liu, J.; Vanmolkot, F.H.M.; Beekman, M.; Wen, K.X.; Amin, N.; Thesing, C.S.; Pijpers, J.A.; Kies, D.A.; Zielman, R.; Boer, I. de; Greevenbroek, M.M.J. van; Arts, I.C.W.; Milaneschi, Y.; Schram, M.T.; Dagnelie, P.C.; Franke, L.; Ikram, M.A.; Ferrari, M.D.; Goeman, J.J.; Slagboom, P.E.; Wijmenga, C.; Stehouwer, C.D.A.; Boomsma, D.I.; Duijn, C.M. van; Penninx, B.W.; Hoen, P.A.C. 't; Terwindt, G.M.; Maagdenberg, A.M.J.M. van den & BBMRI Metabolomics Consortium (2019), Large-scale plasma metabolome analysis reveals alterations in HDL metabolism in migraine, Neurology 92(16): E1899-E1911.
- Cecco, M. de; Ito, T.; Petrashen, A.P.; Elias, A.E.; Skvir, N.J.; Criscione, S.W.; Caligiana, A.; Brocculi, G.; Adney, E.M.; Boeke, J.D.; , O. le; Beausejour, C.; Ambati, J.; Ambati, K.; Simon, M.; Seluanov, A.; Gorbunova, V.; Slagboom, P.E.; Helfand, S.L.; Neretti, N. & Sedivy, J.M. (2019), L1 drives IFN in senescent cells and promotes age-associated inflammation, Nature 566(7742): 73-+.
- Zhernakova A., Kurilshikov A., van den Munckhof I., Slagboom E., Schraa K., Joosten L., Xavier R., Kuipers F., Netea M., Wijmenga C. & Fu J. (2019), Host genetics and microbial impact on plasma metabolites is linked to the cardiovascular risk, European Journal of Human Genetics 27: 785-786.
- Kurilshikov, A.; Munckhof, I.C.L. van den; Chen, L.M.; Bonder, M.J.; Schraa, K.; Rutten, J.H.W.; Riksen, N.P.; Graaf, J. de; Oosting, M.; Sanna, S.; Joosten, L.A.B.; Graaf, M. van der; Brand, T.; Koonen, D.P.Y.; Faassen, M. van; Slagboom, P.E.; Xavier, R.J.; Kuipers, F.; Hofker, M.H.; Wijmenga, C.; Netea, M.G.; Zhernakova, A.; Fu, J. & DEEP Cohort Study (2019), Gut Microbial Associations to Plasma Metabolites Linked to Cardiovascular Phenotypes and Risk A Cross-Sectional Study, Circulation Research 124(12): 1808-1820.
- Watson, H.J.; Yilmaz, Z.; Thorntont, L.M.; Hubel, C.; Coleman, J.R.I.; Gaspar, H.A.; Bryois, J.; Hinney, A.; Leppa, V.M.; Mattheisen, M.; Medland, S.E.; Ripke, S.; Yao, S.Y.; Giusti-Rodriguez, P.; Hanscombe, K.B.; Purves, K.L.; Adan, R.A.H.; Alfredsson, L.; Ando, T.; Andreassen, O.A.; Baker, J.H.; Berrettini, W.H.; Boehm, I.; Boni, C.; Perica, V.B.; Buehren, K.; Burghardt, R.; Cassina, M.; Cichon, S.; Clementi, M.; Cone, R.D.; Courtet, P.; Crow, S.; Crowley, J.J.; Danner, U.N.; Davis, O.S.P.; Zwaan, M. de; Dedoussis, G.; Degortes, D.; DeSocio, J.E.; Dick, D.M.; Dikeos, D.; Dina, C.; Dmitrzak-Weglarz, M.; Docampo, E.; Duncan, L.E.; Egberts, K.; Ehrlich, S.; Escaramis, G.; Eskos, T.; Estivill, X.; Farmer, A.; Favaro, A.; Fernandez-Aranda, F.; Fichter, M.M.; Fischer, K.; Focker, M.; Foretova, L.; Forstner, A.J.; Forzan, M.; Franklin, C.S.; Gallinger, S.; Giegling, I.; Giuranna, J.; Gonidakis, F.; Gorwood, P.; Mayora, M.G.; Guillaume, S.; Guo, Y.R.; Hakonarson, H.; Hatzikotoulas, K.; Hauser, J.; Hebebrand, J.; Helder, S.G.; Herms, S.; Herpertz-Dahlmann, B.; Herzog, W.; Huckins, L.M.; Hudson, J.I.; Imgart, H.; Inoko, H.; Janout, V.; Jimenez-Murcia, S.; Julia, A.; Kalsi, G.; Kaminska, D.; Kaprio, J.; Karhunen, L.; Karwautz, A.; Kas, M.J.H.; Kennedy, J.L.; Keski-Rahkonen, A.; Kiezebrink, K.; Kim, Y.R.; Klareskog, L.; Klump, K.L.; Knudsen, G.P.S.; Via, M.C. la; Hellard, S. le; Levitan, R.D.; Li, D.; Lilenfeld, L.; Lin, B.D.; Lissowska, J.; Luykx, J.; Magistretti, P.J.; Maj, M.; Mannik, K.; Marsal, S.; Marshall, C.R.; Mattingsdal, M.; McDevitt, S.; McGuffin, P.; Metspalu, A.; Meulenbelt, I.; Micali, N.; Mitchell, K.; Monteleone, A.M.; Monteleone, P.; Munn-Chernoff, M.A.; Nacmias, B.; Navratilova, M.; Ntalla, I.; O'Toole, J.K.; Ophoff, R.A.; Padyukov, L.; Palotie, A.; Pantel, J.; Papezova, H.; Pinto, D.; Rabionet, R.; Raevuori, A.; Ramoz, N.; Reichborn-Kjennerud, T.; Ricca, V.; Ripatti, S.; Ritschel, F.; Roberts, M.; Rotondo, A.; Rujescu, D.; Rybakowski, F.; Santonastaso, P.; Scherag, A.; Scherer, S.W.; Schmidt, U.; Schork, N.J.; Schosser, A.; Seitz, J.; Slachtova, L.; Slagboom, P.E.; Landt, M.C.T.S.O. 't; Slopien, A.; Sorbi, S.; Swiatkowska, B.; Szatkiewicz, J.P.; Tachmazidou, I.; Tenconi, E.; Tortorella, A.; Tozzi, F.; Treasure, J.; Tsitsika, A.; Tyszkiewicz-Nwafor, M.; Tziouvas, K.; Elbur, A.A. van; Furth, E.F. van; Wagner, G.; Walton, E.; Widen, E.; Zeggini, E.; Zerwas, S.; Zipfel, S.; Bergen, A.W.; Boden, J.M.; Brandt, H.; Crawford, S.; Halmi, K.A.; Horwood, L.J.; Johnson, C.; Kaplan, A.S.; Kaye, W.H.; Mitchell, J.E.; Olsen, C.M.; Pearson, J.F.; Pedersen, N.L.; Strober, M.; Werge, T.; Whiteman, D.C.; Woodside, D.B.; Stuber, G.D.; Gordon, S.; Grove, J.; Henders, A.K.; Jureus, A.; Kirk, K.M.; Larsen, J.T.; Parker, R.; Petersen, L.; Jordan, J.; Kennedy, M.; Montgomery, G.W.; Wade, T.D.; Birgegard, A.; Lichtenstein, P.; Norring, C.; Landen, M.; Martin, N.G.; Mortensen, P.B.; Sullivan, P.F.; Breen, G.; Bulik, C.M.; Anorexia Nervosa Genetics Initiati & Psychiat Genomics Consortium (2019), Genome-wide association study identifies eight risk loci and implicates metabo-psychiatric origins for anorexia nervosa, Nature Genetics 51(8): 1207-+.
- Chauhan, G.; Adams, H.H.H.; Satizabal, C.L.; Bis, J.C.; Teumer, A.; Sargurupremraj, M.; Hofer, E.; Trompet, S.; Hilal, S.; Smith, A.V.; Jian, X.Q.; Malik, R.; Traylor, M.; Pulit, S.L.; Amouyel, P.; Mazoyer, B.; Zhu, Y.C.; Kaffashian, S.; Schilling, S.; Beecham, G.W.; Montine, T.J.; Schellenberg, G.D.; Kjartansson, O.; Gudnason, V.; Knopman, D.S.; Griswold, M.E.; Windham, B.G.; Gottesman, R.F.; Mosley, T.H.; Schmidt, R.; Saba, Y.; Schmidt, H.; Takeuchi, F.; Yamaguchi, S.; Nabika, T.; Kato, N.; Rajan, K.B.; Aggarwal, N.T.; Jager, P.L. de; Evans, D.A.; Psaty, B.M.; Rotter, J.I.; Rice, K.; Lopez, O.L.; Liao, J.M.; Chen, C.; Cheng, C.Y.; Wong, T.Y.; Ikram, M.K.; Lee, S.J. van der; Amin, N.; Chouraki, V.; DeStefano, A.L.; Aparicio, H.J.; Romero, J.R.; Maillard, P.; DeCarli, C.; Wardlaw, J.M.; Hernandez, M.D.V.; Luciano, M.; Liewald, D.; Deary, I.J.; Starr, J.M.; Bastin, M.E.; Maniega, S.M.; Slagboom, P.E.; Beekman, M.; Deelen, J.; Uh, H.W.; Lemmens, R.; Brodaty, H.; Wright, M.J.; Ames, D.; Boncoraglio, G.B.; Hopewell, J.C.; Beecham, A.H.; Blanton, S.H.; Wright, C.B.; Sacco, R.L.; Wen, W.; Thalamuthu, A.; Armstrong, N.J.; Chong, E.; Schofield, P.R.; Kwok, J.B.; Grond, J. van der; Stott, D.J.; Ford, I.; Jukema, J.W.; Vernooij, M.W.; Hofman, A.; Uitterlinden, A.G.; Lugt, A. van der; Wittfeld, K.; Grabe, H.J.; Hosten, N.; Sarnowski, B. von; Volker, U.; Levi, C.; Jimenez-Conde, J.; Sharma, P.; Sudlow, C.L.M.; Rosand, J.; Woo, D.; Cole, J.W.; Meschia, J.F.; Slowik, A.; Thijs, V.; Lindgren, A.; Melander, O.; Grewal, R.P.; Rundek, T.; Rexrode, K.; Rothwell, P.M.; Arnett, D.K.; Jern, C.; Johnson, J.A.; Benavente, O.R.; Wasssertheil-Smoller, S.; Lee, J.M.; Wong, Q.; Mitchell, B.D.; Rich, S.S.; McArdle, P.F.; Geerlings, M.I.; Graaf, Y. van der; Bakker, P.I.W. de; Asselbergs, F.W.; Srikanth, V.; Thomson, R.; McWhirter, R.; Moran, C.; Callisaya, M.; Phan, T.; Rutten-Jacobs, L.C.A.; Bevan, S.; Tzourio, C.; Mather, K.A.; Sachdev, P.S.; Duijn, C.M. van; Worrall, B.B.; Dichgans, M.; Kittner, S.J.; Markus, H.S.; Ikram, M.A.; Fornage, M.; Launer, L.J.; Seshadri, S.; Longstreth, W.T.; Debette, S.; Stroke Genetics Network SiGN; ISGC; METASTROKE; ADGC & CHARGE Consortium (2019), Genetic and lifestyle risk factors for MRI-defined brain infarcts in a population-based setting, Neurology 92(5): E486-E503.
- Meessen, J.M.T.A.; Fiocco, M.; Leichtenberg, C.S.; Vlieland, T.P.M.V.; Slagboom, P.E. & Nelissen, R.G.H.H. (2019), Frailty Questionnaire Is Not a Strong Prognostic Factor for Functional Outcomes in Hip or Knee Arthroplasty Patients, Geriatric Orthopaedic Surgery and Rehabilitation 10.
- Laan, T. van der; Kloots, T.; Beekman, M.; Kindt, A.; Dubbelman, A.C.; Harms, A.; Duijn, C.M. van; Slagboom, P.E. & Hankemeier, T. (2019), Fast LC-ESI-MS/MS analysis and influence of sampling conditions for gut metabolites in plasma and serum, Scientific Reports 9.
- Dongen, J. van; Zilhao, N.R.; Sugden, K.; Hannon, E.J.; Mill, J.; Caspi, A.; Agnew-Blais, J.; Arseneault, L.; Corcoran, D.L.; Moffitt, T.E.; Poulton, R.; Franke, B.; Boomsma, D.I.; Heijmans, B.T.; t'Hoen, P.A.G.; Meurs, J. van; Isaacs, A.; Jansen, R.; Franke, L.; Pool, R.; Hottenga, J.J.; Greevenbroek, M.M.J. van; Stehouwer, C.D.A.; Kallen, C.J.H. van der; Schalkwijk, C.G.; Wijmenga, C.; Zhernakova, S.; Tigchelaar, E.F.; Slagboom, P.E.; Beekman, M.; Deelen, J.; Heemst, D. van; Veldink, J.H.; Berg, L.H. van den; Duijn, C.M. van; Hofman, B.A.; Uitterlinden, A.G.; Jhamai, P.M.; Verbiest, M.; Suchiman, H.E.D.; Verkerk, M.; Breggen, R. van der; Rooij, J. van; Lakenberg, N.; Mei, H.L.; Iterson, M. van; Galen, M. van; Bot, J.; Zhernakova, D.V.; t'Hof, P. van; Deelen, P.; Nooren, I.; Moed, M.; Vermaat, M.; Luijk, R.; Bonder, M.J.; Dijk, F. van; Arindrarto, W.; Kielbasa, S.M.; Swertz, M.A.; Zwet, E.W. van; t'Hoen, P.B. & BIOS Consortium (2019), Epigenome-wide Association Study of Attention-Deficit/Hyperactivity Disorder Symptoms in Adults, Biological Psychiatry 86(8): 599-607.
- Ramos Y. F., de Almeida R. Coutinho, Mahfouz A., den Hollander W., Lakenberg N., Houtman E., van Hoolwerff M., Suchiman E., Rodriguez-Ruiz A., Slagboom P., Mei H., Kielbasa S. M., Nelissen R. G., Reinders M. & Meulenbelt I. (2019), CIRCULATING MICRO RNAS REFLECTING ONGOING OSTEOARTHRITIS PATHOPHYSIOLOGY IN CARTILAGE AS APPLICABLE BIOMARKERS, Osteoarthritis and Cartilage 27: S69-S69.
- Lee, S.J. van der; Teunissen, C.E.; Pool, R.; Shipley, M.J.; Teumer, A.; Chouraki, V.; Lent, D.M. van; Tynkkynen, J.; Fischer, K.; Hernesniemi, J.; Haller, T.; Singh-Manoux, A.; Verhoeven, A.; Willemsen, G.; Leeuw, F.A. de; Wagner, H.; Dongen, J. van; Hertel, J.; Budde, K.; Dijk, K.W. van; Weinhold, L.; Ikram, M.A.; Pietzner, M.; Perola, M.; Wagner, M.; Friedrich, N.; Slagboom, P.E.; Scheltens, P.; Yang, Q.; Gertzen, R.E.; Egert, S.; Li, S.; Hankemeier, T.; Beijsterveldt, C.E.M. van; Vasan, R.S.; Maier, W.; Peeters, C.F.W.; Grabe, H.J.; Ramirez, A.; Seshadri, S.; Metspalu, A.; Kivimaki, M.; Salomaa, V.; Demirkan, A.; Boomsma, D.I.; Flier, W.M. van der; Amin, N. & Duijn, C.M. van (2019), Circulating metabolites and general cognitive ability and dementia: Evidence from 11 cohort studies (vol 14, pg 707, 2018), Alzheimer's and Dementia 15(2): 319-319.
- Poort, E.K.J. van der; Gunn, D.A.; Beekman, M.; Griffiths, C.E.M.; Slagboom, P.E.; Heemst, D. van & Noordam, R. (2019), Basal cell carcinoma genetic susceptibility increases the rate of skin ageing: a Mendelian randomization study, Journal of the European Academy of Dermatology and Venereology.
- Mandaviya, P.R.; Joehanes, R.; Brody, J.; Castillo-Fernandez, J.E.; Dekkers, K.F.; , A.N. do; Graff, M.; Hanninen, I.K.; Tanaka, T.; Jonge, E.A.L. de; Kiefte-de Jong, J.C.; Absher, D.M.; Aslibekyan, S.; Rijke, Y.B. de; Fornage, M.; Hernandez, D.G.; Hurme, M.A.; Ikram, M.A.; Jacques, P.F.; Justice, A.E.; Kiel, D.P.; Lemaitre, R.N.; Mendelson, M.M.; Mikkila, V.; Moore, A.Z.; Pallister, T.; Raitakari, O.T.; Schalkwijk, C.G.; Sha, J.; Slagboom, E.P.E.; Smith, C.E.; Stehouwer, C.D.A.; Tsai, P.C.; Uitterlinden, A.G.; Kallen, C.J.H. van der; Heemst, D. van; Arnett, D.K.; Bandinelli, S.; Bell, J.T.; Heijmans, B.T.; Lehtimaki, T.; Levy, D.; North, K.E.; Sotoodehnia, N.; Greevenbroek, M.M.J. van; Meurs, J.B.J. van; Heil, S.G.; BIOS Consortium; CHARGE Consortium Epigenetics & CHARGE Consortium Nutr Working Grp (2019), Association of dietary folate and vitamin B-12 intake with genome-wide DNA methylation in blood: a large-scale epigenome-wide association analysis in 5841 individuals, The American Journal of Clinical Nutrition 110(2): 437-450.
- Lee, S.J. van der; Conway, O.J.; Jansen, I.; Carrasquillo, M.M.; Kleineidam, L.; Akker, E. van den; Hernandez, I.; Eijk, K.R. van; Stringa, N.; Chen, J.A.; Zettergren, A.; Andlauer, T.F.M.; Diez-Fairen, M.; Simon-Sanchez, J.; Lleo, A.; Zetterberg, H.; Nygaard, M.; Blauwendraat, C.; Savage, J.E.; Mengel-From, J.; Moreno-Grau, S.; Wagner, M.; Fortea, J.; Keogh, M.J.; Blennow, K.; Skoog, I.; Friese, M.A.; Pletnikova, O.; Zulaica, M.; Lage, C.; Rojas, I. de; Riedel-Heller, S.; Illan-Gala, I.; Wei, W.; Jeune, B.; Orellana, A.; Bergh, F.T.; Wang, X.; Hulsman, M.; Beker, N.; Tesi, N.; Morris, C.M.; Indakoetxea, B.; Collij, L.E.; Scherer, M.; Morenas-Rodriguez, E.; Ironside, J.W.; Berckel, B.N.M. van; Alcolea, D.; Wiendl, H.; Strickland, S.L.; Pastor, P.; Rodriguez Rodriguez, E.; Boeve, B.F.; Petersen, R.C.; Ferman, T.J.; Gerpen, J.A. van; Reinders, M.J.T.; Uitti, R.J.; Tarraga, L.; Maier, W.; Dols-Icardo, O.; Kawalia, A.; Dalmasso, M.C.; Boada, M.; Zettl, U.K.; Schoor, N.M. van; Beekman, M.; Allen, M.; Masliah, E.; Munain, A.L. de; Pantelyat, A.; Wszolek, Z.K.; Ross, O.A.; Dickson, D.W.; Graff-Radford, N.R.; Knopman, D.; Rademakers, R.; Lemstra, A.W.; Pijnenburg, Y.A.L.; Scheltens, P.; Gasser, T.; Chinnery, P.F.; Hemmer, B.; Huisman, M.A.; Troncoso, J.; Moreno, F.; Nohr, E.A.; Sorensen, T.I.A.; Heutink, P.; Sanchez-Juan, P.; Posthuma, D.; Clarimon, J.; Christensen, K.; Ertekin-Taner, N.; Scholz, S.W.; Ramirez, A.; Ruiz, A.; Slagboom, E.; Flier, W.M. van der; Holstege, H.; DESGESCO Dementia Genetics; EADB Alzheimer Dis European; IFGC Int FTD-Genomics; IPDGC Int Parkinson Dis Genomics; RiMod-FTD Risk Modifying; Netherlands Brain Bank NBB & GIFT Genetic Invest (2019), A nonsynonymous mutation in PLCG2 reduces the risk of Alzheimer's disease, dementia with Lewy bodies and frontotemporal dementia, and increases the likelihood of longevity, Acta Neuropathologica 138(2): 237-250.
- Hollander, W. den; Pulyakhina, I.; Boer, C.; Bomer, N.; Breggen, R. van der; Arindrarto, W.; Almeida, R.C. de; Lakenberg, N.; Sentner, T.; Laros, J.F.J.; Hoen, P.A.C. 't; Slagboom, E.P.E.; Nelissen, R.G.H.H.; Meurs, J. van; Ramos, Y.F.M. & Meulenbelt, I. (2019), Annotating Transcriptional Effects of Genetic Variants in Disease-Relevant Tissue: Transcriptome-Wide Allelic Imbalance in Osteoarthritic Cartilage, Arthritis and Rheumatology 71(4): 561-570.
- Deelen, J.; Kettunen, J.; Fischer, K.; Spek, A. van der; Trompet, S.; Kastenmuller, G.; Boyd, A.; Zierer, J.; Akker, E.B. van den; Ala-Korpela, M.; Amin, N.; Demirkan, A.; Ghanbari, M.; Heemst, D. van; Ikram, M.A.; Klinken, J.B. van; Mooijaart, S.P.; Peters, A.; Salomaa, V.; Sattar, N.; Spector, T.D.; Tiemeier, H.; Verhoeven, A.; Waldenberger, M.; Wurtz, P.; Smith, G.D.; Metspalu, A.; Perola, M.; Menni, C.; Geleijnse, J.M.; Drenos, F.; Beekman, M.; Jukema, J.W.; Duijn, C.M. van & Slagboom, P.E. (2019), A metabolic profile of all-cause mortality risk identified in an observational study of 44,168 individuals, Nature Communications 10.
- Deelen, J.; Evans, D.S.; Arking, D.E.; Tesi, N.; Nygaard, M.; Liu, X.M.; Wojczynski, M.K.; Biggs, M.L.; Spek, A. van der; Atzmon, G.; Ware, E.B.; Sarnowski, C.; Smith, A.V.; Seppala, I.; Cordell, H.J.; Dose, J.; Amin, N.; Arnold, A.M.; Ayers, K.L.; Barzilai, N.; Becker, E.J.; Beekman, M.; Blanche, H.; Christensen, K.; Christiansen, L.; Collerton, J.C.; Cubaynes, S.; Cummings, S.R.; Davies, K.; Debrabant, B.; Deleuze, J.F.; Duncan, R.; Faul, J.D.; Franceschi, C.; Galan, P.; Gudnaso, V.; Harris, T.B.; Huisman, M.; Hurme, M.A.; Jagger, C.; Jansen, I.; Jylha, M.; Kahonen, M.; Karasik, D.; Kardia, S.L.R.; Kingston, A.; Kirkwood, T.B.L.; Launer, L.J.; Lehtimaki, T.; Lieb, W.G.; Lyytikainen, L.P.; Martin-Ruiz, C.; Min, J.X.; Nebe, A.; Newman, A.B.; Nie, C.; Nohr, E.A.; Orwoll, E.S.; Perls, T.T.; Province, M.A.; Psat, B.M.; Raitakari, O.T.; Reinders, M.J.T.; Robine, J.M.; Rotter, J.I.; Sebastiani, P.; Smith, J.; Sorensen, T.I.A.; Taylor, K.D.; Uitterlinden, A.G.; Flier, W. van der; Lee, S.J. van der; Duijn, C.M. van; Heemst, D. van; Vaupel, J.W.; Weir, D.; Ye, K.; Zeng, Y.; Zheng, W.L.; Holstege, H.; Kiel, D.P.; Lunetta, K.L.; Slagboom, P.E. & Murabito, J.M. (2019), A meta-analysis of genome-wide association studies identifies multiple longevity genes, Nature Communications 10.
- Lee, S.J. van der; Knol, M.J.; Chauhan, G.; Satizabal, C.L.; Smith, A.V.; Hofer, E.; Bis, J.C.; Hibar, D.P.; Hilal, S.; Akker, E.B. van den; Arfanakis, K.; Bernard, M.; Yanek, L.R.; Amin, N.; Crivello, F.; Cheung, J.W.; Harris, T.B.; Saba, Y.; Lopez, O.L.; Li, S.; Grond, J. van der; Yu, L.; Paus, T.; Roshchupkin, G.V.; Amouyel, P.; Jahanshad, N.; Taylor, K.D.; Yang, Q.; Mathias, R.A.; Boehringer, S.; Mazoyer, B.; Rice, K.; Cheng, C.Y.; Maillard, P.; Heemst, D. van; Wong, T.Y.; Niessen, W.J.; Beiser, A.S.; Beekman, M.; Zhao, W.T.; Nyquist, P.A.; Chen, C.; Launer, L.J.; Psaty, B.M.; Ikram, M.K.; Vernooij, M.W.; Schmidt, H.; Pausova, Z.; Becker, D.M.; Jager, P.L. de; Thompson, P.M.; Duijn, C.M. van; Bennett, D.A.; Slagboom, P.E.; Schmidt, R.; Longstreth, W.T.; Ikram, M.A.; Seshadri, S.; Debette, S.; Gudnason, V.; Adams, H.H.H. & DeCarli, C. (2019), A genome-wide association study identifies genetic loci associated with specific lobar brain volumes, Communications Biology 2.
- Shvetsova, E.; Sofronova, A.; Monajemi, R.; Gagalova, K.; Draisma, H.H.M.; White, S.J.; Santen, G.W.E.; Lopes, S.M.C.D.; Heijmans, B.T.; Meurs, J. van; Jansen, R.; Franke, L.; Kielbasa, S.M.; Dunnen, J.T. den; Hoen, P.A.C. 't; Boomsma, D.I.; Pool, R.; Dongen, J. van; Hottenga, J.J.; Greevenbroek, M.M.J. van; Stehouwer, C. da; Kallen, C.J.H. van der; Schalkwijk, C.G.; Wijmenga, C.; Zhernakova, S.; Tigchelaar, E.F.; Slagboom, P.E.; Beekman, M.; Deelen, J.; Heemst, D. van; Veldink, J.H.; Berg, L.H. van den; Duijn, C.M. van; Hofman, B.A.; Uitterlinden, A.G.; Jhamai, P.M.; Verbiest, M.; Suchiman, H.E.D.; Verkerk, M.; Breggen, R. van der; Rooij, J. van; Lakenberg, N.; Mei, H.L.; Bot, J.; Zhernakova, D.V.; Hof, P.V. 't; Deelen, P.; Nooren, I.; Moed, M.; Vermaat, M.; Luijk, R.; Bonder, M.J.; Iterson, M. van; Dijk, F. van; Galen, M. van; Arindrarto, W.; Kielbasa, S.M.; Swertz, M.A.; Zwet, E.W. van; Isaacs, A.; Francioli, L.C.; Menelaou, A.; Pulit, S.L.; Dijk, F. van; Palamara, P.F.; Elbers, C.C.; Neerincx, P.B.; Ye, K.; Guryev, V.; Kloosterman, W.P.; Deelen, P.; Abdellaoui, A.; Leeuwen, E.M. van; Oven, M. van; Vermaat, M.; Li, M.; Laros, J.F.; Karssen, L.C.; Kanterakis, A.; Amin, N.; Hottenga, J.J.; Lameijer, E.W.; Kattenberg, M.; Dijkstra, M.; Byelas, H.; Setten, J. van; Schaik, B.D. van; Bot, J.; Nijman, I.J.; Renkens, I.; Marschall, T.; Schonhuth, A.; Hehir-Kwa, J.Y.; Handsaker, R.E.; Polak, P.; Sohail, M.; Vuzman, D.; Hormozdiari, F.; Enckevort, D. van; Mei, H.; Koval, V.; Moed, M.H.; Velde, K.J. van der; Rivadeneira, F.; Estrada, K.; Medina-Gomez, C.; Isaacs, A.; McCarroll, S.A.; Beekman, M.; Craen, A.J. de; Suchiman, H.E.; Hofman, B.A.; Oostra, B.; Uitterlinden, A.G.; Willemsen, G.; Platteel, M.; Veldink, J.H.; Berg, L.H. van den; Pitts, S.J.; Potluri, S.; Sundar, P.; Cox, D.R.; Sunyaev, S.R.; Dunnen, J.T. den; Stoneking, M.; Knijff, P. de; Kayser, M.; Li, Q.; Li, Y.; , Y. du; Chen, R.; Cao, H.; Li, N.; Cao, S.; Wang, J.; Bovenberg, J.A.; Pe'er, I.; Slagboom, P.E.; Duijn, C.M. van; Boomsma, D.I.; Ommen, G.J. van; Bakker, P.I. de; Swertz, M.A.; Wijmenga, C.; BIOS Consortium & GoNL Consortium (2019), Skewed X-inactivation is common in the general female population, European Journal of Human Genetics 27(3): 455-465.
- Bas J.M., Harrewijn A., Tissier R.L.M., Van der Molen M.J.W., Van Steenbergen H., Van Vliet I.M., Reichart C.G., Houwing-Duistermaat J.J., Slagboom P., Van der Wee N.J.A. & Westenberg P.M. (2018), The Leiden Family Lab study on Social Anxiety Disorder: A multiplex, multigenerational family study on neurocognitive endophenotypes, International Journal of Methods in Psychiatric Research 27(2): e1616.
- Lee S.J. van der, Teunissen C.E., Pool R., Shipley M.J., Teumer A., Chouraki V., Melo Van Lent D., Tynkkynen J., Fischer K., Hernesniemi J., Haller T., Singh-Manoux A., Verhoeven A., Willemsen G., Leeuw F.A. de, Dongen J. van, Wagner H., Budde K., Hertel J., Weinhold L., Willems Van Dijk J.A.P., Pietzner M., Ikram M.A., Wagner M., Perola M., Slagboom P., Friedrich N., Yang Q., Scheltens P., Egert S., Gertzen R.E., Beijsterveldt C.E.M. van, Vasan R.S., Li S., Hankemeier T., Grabe H.J., Ramirez A., Maier W., Peeters C.F.W., Kivimäki M., Salomaa V., Seshadri S., Metspalu A., Flier W.M. van der, Amin N., Demirkan A., Boomsma D.I. & Duijn C.M. van (2018), Circulating metabolites and general cognitive ability and dementia: Evidence from 11 cohort studies, Alzheimer's & Dementia 14(6): 707-722.
- Wahl, A.; Akker, E. van den; Klaric, L.; Stambuk, J.; Benedetti, E.; Plomp, R.; Razdorov, G.; Trbojevic-Akmacic, I.; Deelen, J.; Heemst, D. van; Slagboom, P.E.; Vuckovic, F.; Grallert, H.; Krumsiek, J.; Strauch, K.; Peters, A.; Meitinger, T.; Hayward, C.; Wuhrer, M.; Beekman, M.; Lauc, G. & Gieger, C. (2018), Genome-Wide Association Study on Immunoglobulin G Glycosylation Patterns, Frontiers in Immunology 9.
- Wahl, A.; Kasela, S.; Carnero-Montoro, E.; Iterson, M. van; Stambuk, J.; Sharma, S.; Akker, E. van den; Klaric, L.; Benedetti, E.; Razdorov, G.; Trbojevic-Akmacic, I.; Vuckovic, F.; Ugrina, I.; Beekman, M.; Deelen, J.; Heemst, D. van; Heijmans, B.T.; Wuhrer, M.; Plomp, R.; Keser, T.; Simurina, M.; Pavic, T.; Gudelj, I.; Kristic, J.; Grallert, H.; Kunze, S.; Peters, A.; Bell, J.T.; Spector, T.D.; Milani, L.; Slagboom, P.E.; Lauc, G.; Gieger, C. & B I O S Consortium (2018), IgG glycosylation and DNA methylation are interconnected with smoking, BBA - General Subjects 1862(3): 637-648.
- Floyd, J.S.; Sitlani, C.M.; Avery, C.L.; Noordam, R.; Li, X.; Smith, A.V.; Gogarten, S.M.; Li, J.; Broer, L.; Evans, D.S.; Trompet, S.; Brody, J.A.; Stewart, J.D.; Eicher, J.D.; Seyerle, A.A.; Roach, J.; Lange, L.A.; Lin, H.J.; Kors, J.A.; Harris, T.B.; Li-Gao, R.; Sattar, N.; Cummings, S.R.; Wiggins, K.L.; Napier, M.D.; Sturmer, T.; Bis, J.C.; Kerr, K.; Uitterlinden, A.G.; Taylor, K.D.; Stott, D.J.; Mutsert, R. de; Launer, L.J.; Busch, E.L.; Mendez-Giraldez, R.; Sotoodehnia, N.; Soliman, E.Z.; Li, Y.; Duan, Q.; Rosendaal, F.R.; Slagboom, P.E.; Wilhelmsen, K.C.; Reiner, A.P.; Chen, Y.D.; Heckbert, S.R.; Kaplan, R.C.; Rice, K.M.; Jukema, J.W.; Johnson, A.D.; Liu, Y.; Mook-Kanamori, D.O.; Gudnason, V.; Wilson, J.G.; Rotter, J.I.; Laurie, C.C.; Psaty, B.M.; Whitsel, E.A.; Cupples, L.A. & Stricker, B.H. (2018), Large-scale pharmacogenomic study of sulfonylureas and the QT, JT and QRS intervals: CHARGE Pharmacogenomics Working Group, Pharmacogenomics Journal 18(1): 127-135.
- Jenny van Dongen, BIOS consortium, Marc Jan Bonder, Koen F. Dekkers, Michel G. Nivard, Maarten van Iterson, Gonneke Willemsen, Marian Beekman, Ashley van der Spek, Joyce van Meurs, Lude Franke, Bastiaan T. Heijmans, Cornelia van Duijn, P. Eline Slagboom & Dorret I. Boomsma (2018), DNA methylation signatures of educational attainment, npj Science of Learning 3(7).
- Tobi, E.W.; Slieker, R.C.; Luijk, R.; Dekkers, K.F.; Stein, A.D.; Xu, K.M.; Slagboom, P.E.; Zwet, E.W. van; Lumey, L.H.; Heijmans, B.T. & Biobank-Based Integrative Omics (2018), DNA methylation as a mediator of the association between prenatal adversity and risk factors for metabolic disease in adulthood, Science Advances 4(1).
- Zeng, Y.; Nie, C.; Min, J.X.; Chen, H.; Liu, X.M.; Ye, R.; Chen, Z.H.; Bai, C.; Xie, E.J.; Yin, Z.X.; Lv, Y.B.; Lu, J.H.; Li, J.X.; Ni, T.; Bolund, L.; Land, K.C.; Yashin, A.; O'Rand, A.M.; Sun, L.; Yang, Z.; Tao, W.; Gurinovich, A.; Franceschi, C.; Xie, J.C.; Gu, J.; Hou, Y.; Liu, X.; Xu, X.; Robine, J.M.; Deelen, I.; Sebastiani, P.; Slagboom, E.; Perls, T.; Hauser, E.; Gottschalk, W.; Tan, Q.H.; Christensen, K.; Shi, X.M.; Lutz, M.; Tian, X.L.; Yang, H.M. & Vaupel, J. (2018), Sex Differences in Genetic Associations With Longevity, Jama Network Open 1(4).
- Ligthart, S.; Vaez, A.; Vosa, U.; Stathopoulou, M.G.; Vries, P.S. de; Prins, B.P.; Most, P.J. van der; Tanaka, T.; Naderi, E.; Rose, L.M.; Wu, Y.; Karlsson, R.; Barbalic, M.; Lin, H.H.; Pool, R.; Zhu, G.; Mace, A.; Sidore, C.; Trompet, S.; Mangino, M.; Sabater-Lleal, M.; Kemp, J.P.; Abbasi, A.; Kacprowski, T.; Verweij, N.; Smith, A.V.; Huang, T.; Marzi, C.; Feitosa, M.F.; Lohman, K.K.; Kleber, M.E.; Milaneschi, Y.; Mueller, C.; Huq, M.; Vlachopoulou, E.; Lyytikainen, L.P.; Oldmeadow, C.; Deelen, J.; Perola, M.; Zhao, J.H.; Feenstra, B.; Amini, M.; Lahti, J.; Schraut, K.E.; Fornage, M.; Suktitipat, B.; Chen, W.M.; Li, X.H.; Nutile, T.; Malerba, G.; Luan, J.A.; Bak, T.; Schork, N.; Greco, M.F. del; Thiering, E.; Mahajan, A.; Marioni, R.E.; Mihailov, E.; Eriksson, J.; Ozel, A.B.; Zhang, W.H.; Nethander, M.; Cheng, Y.C.; Aslibekyan, S.; Ang, W.; Gandin, I.; Yengo, L.; Portas, L.; Kooperberg, C.; Hofer, E.; Rajan, K.B.; Schurmann, C.; Hollander, W. den; Ahluwalia, T.S.; Zhao, J.; Draisma, H.H.M.; Ford, I.; Timpson, N.; Teumer, A.; Huang, H.Y.; Wahl, S.; Liu, Y.M.; Huang, J.; Uh, H.W.; Geller, F.; Joshi, P.K.; Yanek, L.R.; Trabetti, E.; Lehne, B.; Vozzi, D.; Verbanck, M.; Biino, G.; Saba, Y.; Meulenbelt, I.; O'Connell, J.R.; Laakso, M.; Giulianini, F.; Magnusson, P.K.E.; Ballantyne, C.M.; Hottenga, J.J.; Montgomery, G.; Rivadineira, F.; Rueedi, R.; Steri, M.; Herzig, K.H.; Stott, D.J.; Menni, C.; Franberg, M.; St Pourcain, B.; Felix, S.B.; Pers, T.H.; Bakker, S.J.L.; Kraft, P.; Peters, A.; Vaidya, D.; Delgado, G.; Smit, J.H.; Grossmann, V.; Sinisalo, J.; Seppala, I.; Williams, S.R.; Holliday, E.G.; Moed, M.; Langenberg, C.; Raikkonen, K.; Ding, J.Z.; Campbell, H.; Sale, M.M.; Chen, Y.D.I.; James, A.L.; Ruggiero, D.; Soranzo, N.; Hartman, C.A.; Smith, E.N.; Berenson, G.S.; Fuchsberger, C.; Hernandez, D.; Tiesler, C.M.T.; Giedraitis, V.; Liewald, D.; Fischer, K.; Mellstrom, D.; Larsson, A.; Wang, Y.M.; Scott, W.R.; Lorentzon, M.; Beilby, J.; Ryan, K.A.; Pennell, C.E.; Vuckovic, D.; Balkau, B.; Concas, M.P.; Schmidt, R.; Leon, C.F.M. de; Bottinger, E.P.; Kloppenburg, M.; Paternoster, L.; Boehnke, M.; Musk, A.W.; Willemsen, G.; Evans, D.M.; Madden, P.A.F.; Kahonen, M.; Kutalik, Z.; Zoledziewska, M.; Karhunen, V.; Kritchevsky, S.B.; Sattar, N.; Lachance, G.; Clarke, R.; Harris, T.B.; Raitakari, O.T.; Attia, J.R.; Heemst, D. van; Kajantie, E.; Sorice, R.; Gambaro, G.; Scott, R.A.; Hicks, A.A.; Ferrucci, L.; Standl, M.; Lindgren, C.M.; Starr, J.M.; Karlsson, M.; Lind, L.; Li, J.Z.; Chambers, J.C.; Mori, T.A.; Geus, E.J.C.N. de; Heath, A.C.; Martin, N.G.; Auvinen, J.; Buckley, B.M.; Craen, A.J.M. de; Waldenberger, M.; Strauch, K.; Meitinger, T.; Scott, R.J.; McEvoy, M.; Beekman, M.; Bombieri, C.; Ridker, P.M.; Mohlke, K.L.; Pedersen, N.L.; Morrison, A.C.; Boomsma, D.I.; Whitfield, J.B.; Strachan, D.P.; Hofman, A.; Vollenweider, P.; Cucca, F.; Jarvelin, M.R.; Jukema, J.W.; Spector, T.D.; Hamsten, A.; Zeller, T.; Uitterlinden, A.G.; Nauck, M.; Gudnason, V.; Qi, L.; Grallert, H.; Borecki, I.B.; Rotter, J.I.; Marz, W.; Wild, P.S.; Lokki, M.L.; Boyle, M.; Salomaa, V.; Melbye, M.; Eriksson, J.G.; Wilson, J.F.; Penninx, B.W.J.H.; Becker, D.M.; Worrall, B.B.; Gibson, G.; Krauss, R.M.; Ciullo, M.; Zaza, G.; Wareham, N.J.; Oldehinkel, A.J.; Palmer, L.J.; Murray, S.S.; Pramstaller, P.P.; Bandinelli, S.; Heinrich, J.; Ingelsson, E.; Deary, I.J.; Magi, R.; Vandenput, L.; Harst, P. van der; Desch, K.C.; Kooner, J.S.; Ohlsson, C.; Hayward, C.; Lehtimaki, T.; Shuldiner, A.R.; Arnett, D.K.; Beilin, L.J.; Robino, A.; Froguel, P.; Pirastu, M.; Jess, T.; Koenig, W.; Loos, R.J.F.; Evans, D.A.; Schmidt, H.; Smith, G.D.; Slagboom, P.E.; Eiriksdottir, G.; Morris, A.P.; Psaty, B.M.; Tracy, R.P.; Nolte, I.M.; Boerwinkle, E.; Visvikis-Siest, S.; Reiner, A.P.; Gross, M.; Bis, J.C.; Franke, L.; Franco, O.H.; Benjamin, E.J.; Chasman, D.I.; Dupuis, J.; Snieder, H.; Dehghan, A.; Alizadeh, B.Z.; LifeLines Cohort Study & CHAR (2018), Genome Analyses of >200,000 Individuals Identify 58 Loci for Chronic Inflammation and Highlight Pathways that Link Inflammation and Complex Disorders, American Journal of Human Genetics 103(5): 691-706.
- Berg, N. van den; Rodriguez-Girondo, M.; Craen, A.J.M. de; Houwing-Duistermaat, J.J.; Beekman, M. & Slagboom, P.E. (2018), Longevity Around the Turn of the 20th Century: Life-Long Sustained Survival Advantage for Parents of Today's Nonagenarians, Journals of Gerontology, Series A 73(10): 1295-1302.
- Teumer, A.; Chaker, L.; Groeneweg, S.; Li, Y.; Munno, C. di; Barbieri, C.; Schultheiss, U.T.; Traglia, M.; Ahluwalia, T.S.; Akiyama, M.; Appel, E.V.R.; Arking, D.E.; Arnold, A.; Astrup, A.; Beekman, M.; Beilby, J.P.; Bekaert, S.; Boerwinkle, E.; Brown, S.J.; Buyzere, M. de; Campbell, P.J.; Ceresini, G.; Cerqueira, C.; Cucca, F.; Deary, I.J.; Deelen, J.; Eckardt, K.U.; Ekici, A.B.; Eriksson, J.G.; Ferrrucci, L.; Fiers, T.; Fiorillo, E.; Ford, I.; Fox, C.S.; Fuchsberger, C.; Galesloot, T.E.; Gieger, C.; Gogele, M.; Grandi, A. de; Grarup, N.; Greiser, K.H.; Haljas, K.; Hansen, T.; Harris, S.E.; Heemst, D. van; Heijer, M. den; Hicks, A.A.; Hollander, W. den; Homuth, G.; Hui, J.N.; Ikrarm, M.A.; Ittermann, T.; Jensen, R.A.; Jing, J.; Jukema, J.W.; Kajantie, E.; Kamatani, Y.; Kasbohm, E.; Kaufman, J.M.; Kiemeney, L.A.; Kloppenburg, M.; Kronenberg, F.; Kubo, M.; Lahti, J.; Lapauw, B.; Li, S.; Liewald, D.C.M.; Lim, E.M.; Linneberg, A.; Marina, M.; Mascalzoni, D.; Matsuda, K.; Medenwald, D.; Meisinger, C.; Meulenbelt, I.; Meyer, T. de; Schwabedissen, H.E.M. zu; Mikolajczyk, R.; Moed, M.; Netea-Maier, R.T.; Nolte, I.M.; Okadah, Y.; Pala, M.; Pattaro, C.; Pedersen, O.; Petersmann, A.; Porcu, E.; Postmus, I.; Pramstaller, P.P.; Psaty, B.M.; Ramos, Y.F.M.; Rawal, R.; Redmond, P.; Richards, J.B.; Rietzschel, E.R.; Rivadeneira, F.; Roef, G.; Rotter, J.I.; Sala, C.F.; Schlessinger, D.; Selvin, E.; Slagboom, P.E.; Soranzo, N.; Sorensen, T.I.A.; Spector, T.D.; Starr, J.M.; Stott, D.J.; Taes, Y.; Taliun, D.; Tanaka, T.; Thuesen, B.; Tiller, D.; Toniolo, D.; Uitterlinden, A.G.; Visser, W.E.; Walsh, J.P.; Wilson, S.G.; Wolffenbuttel, B.H.R.; Yang, Q.; Zheng, H.F.; Cappola, A.; Peeters, R.P.; Naitza, S.; Volzke, H.; Sanna, S.; Kottgen, A.; Visser, T.J.; Medici, M. & Lifelines Cohort Study (2018), Genome-wide analyses identify a role for SLC17A4 and AADAT in thyroid hormone regulation, Nature Communications 9.
- Hart, L.M. 't; Vogelzangs, N.; Mook-Kanamori, D.O.; Brahimaj, A.; Nano, J.; Heijden, A.A.W.A. van der; Dijk, K.W. van; Slieker, R.C.; Steyerberg, E.W.; Ikram, M.A.; Beekman, M.; Boomsma, D.I.; Duijn, C.M. van; Slagboom, P.E.; Stehouwer, C.D.A.; Schalkwijk, C.G.; Arts, I.C.W.; Dekker, J.M.; Dehghan, A.; Muka, T.; Kallen, C.J.H. van der; Nijpels, G. & Greevenbroek, M.M.J. van (2018), Blood Metabolomic Measures Associate With Present and Future Glycemic Control in Type 2 Diabetes, Journal of Clinical Endocrinology and Metabolism 103(12): 4569-4579.
- Luijk, R.; Wu, H.Y.; Ward-Caviness, C.K.; Hannon, E.; Carnero-Montoro, E.; Min, J.L.; Mandaviya, P.; Muller-Nurasyid, M.; Mei, H.; Maarel, S.M. van der; Relton, C.; Mill, J.; Waldenberger, M.; Bell, J.T.; Jansen, R.; Zhernakova, A.; Franke, L.; Hoen, P.A.C. 't; Boomsma, D.I.; Duijn, C.M. van; Greevenbroek, M.M.J. van; Veldink, J.H.; Wijmenga, C.; Meurs, J. van; Daxinger, L.; Slagboom, P.E.; Zwet, E.W. van; Heijmans, B.T. & BIOS Consortium (2018), Autosomal genetic variation is associated with DNA methylation in regions variably escaping X-chromosome inactivation, Nature Communications 9.
- Parmar, P.; Lowry, E.; Cugliari, G.; Suderman, M.; Wilson, R.; Karhunen, V.; Andrew, T.; Wiklund, P.; Wielscher, M.; Guarrera, S.; Teumer, A.; Lehne, B.; Milani, L.; Klein, N. de; Mishra, P.P.; Melton, P.E.; Mandaviya, P.R.; Kasela, S.; Nano, J.; Zhang, W.H.; Zhang, Y.; Uitterlinden, A.G.; Peters, A.; Schottker, B.; Gieger, C.; Anderson, D.; Boomsma, D.I.; Grabe, H.J.; Panico, S.; Veldink, J.H.; Meurs, J.B.J. van; Berg, L. van den; Beilin, L.J.; Franke, L.; Loh, M.; Greevenbroek, M.M.J. van; Nauck, M.; Kahonen, M.; Hurme, M.A.; Raitakari, O.T.; Franco, O.H.; Slagboom, P.E.; Harst, P. van der; Kunze, S.; Felix, S.B.; Zhang, T.; Chen, W.; Mori, T.A.; Bonnefond, A.; Heijmans, B.T.; Muka, T.; Kooner, J.S.; Fischer, K.; Waldenberger, M.; Froguel, P.; Huang, R.C.; Lehtimaki, T.; Rathmann, W.; Relton, C.L.; Matullo, G.; Brenner, H.; Verweij, N.; Li, S.X.; Chambers, J.C.; Jarvelin, M.R.; Sebert, S.; BIOS Consortium & GLOBAL Meth QTL (2018), Association of maternal prenatal smoking GFI1-locus and cardiometabolic phenotypes in 18,212 adults, EBioMedicine 38: 206-216.
- Ouwens, K.G.; Jansen, R.; Tolhuis, B.; Slagboom, P.E.; Penninx, B.W.J.H. & Boomsma, D.I. (2018), A characterization of postzygotic mutations identified in monozygotic twins, Human Mutation 39(10): 1393-1401.
- Meessen, J.M.T.A.; Leichtenberg, C.S.; Tilbury, C.; Kaptein, B.L.; Koster, L.A.; Slagboom, P.E.; Verdegaal, S.H.M.; Onstenk, R.; Linden-van der Zwaag, H.M.J. van der; Kaptijn, H.; Vehmeijer, S.B.W.; Marijnissen, W.J.C.; Damen, P.J.; Nelissen, R.G.H.H. & Vlieland, T.P.M.V. (2018), Frailty in end-stage hip or knee osteoarthritis: validation of the Groningen Frailty Indicator (GFI) questionnaire, Rheumatology International 38(5): 917-924.
- Luijk, R.; Dekkers, K.F.; Iterson, M. van; Arindrarto, W.; Claringbould, A.; Hop, P.; Boomsma, D.I.; Duijn, C.M. van; Greevenbroek, M.M.J. van; Veldink, J.H.; Wijmenga, C.; Franke, L.; Hoend, P.A.C. 't; Jansen, R.; Meurs, J. van; Mei, H.L.; Slagboomi, P.E.; Heijmans, B.T.; Zwet, E.W. van & BIOS Consortium (2018), Genome-wide identification of directed gene networks using large-scale population genomics data, Nature Communications 9.
- Oei, N.Y.L.; Jansen, S.W.; Veer, I.M.; Slagboom, P.E.; Grond, J. van de & Heemst, D. van (2018), Stress evokes stronger medial posterior cingulate deactivations during emotional distraction in slower paced aging, Biological Psychology 135: 84-92.
- Slagboom P. E. (2018), Human aging research - the biomarker challenge, Zeitschrift f�r Gerontologie und Geriatrie 51: 8-8.
- Waaijer, M.E.C.; Gunn, D.A.; Heemst, D. van; Slagboom, P.E.; Sedivy, J.M.; Dirks, R.W.; Tanke, H.J.; Westendorp, R.G.J. & Maier, A.B. (2018), Do senescence markers correlate in vitro and in situ within individual human donors?, Aging 10(2): 278-289.
- Partridge, L.; Deelen, J. & Slagboom, P.E. (2018), Facing up to the global challenges of ageing, Nature 561(7721): 45-56.
- Hamer, M.A.; Pardo, L.M.; Jacobs, L.C.; Deelen, J.; Uitterlinden, A.G.; Slagboom, E.; Heemst, D. van; Uh, H.W.; Beekman, M.; Kayser, M.; Liu, F.; Gunn, D.A. & Nijsten, T. (2018), Facial Wrinkles in Europeans: A Genome-Wide Association Study, Journal of Investigative Dermatology 138(8): 1877-1880.
- Slieker, R.C.; Relton, C.L.; Gaunt, T.R.; Slagboom, P.E. & Heijmans, B.T. (2018), Age-related DNA methylation changes are tissue-specific with ELOVL2 promoter methylation as exception, Epigenetics and Chromatin 11.
- Lee, S.J. van der; Teunissen, C.E.; Pool, R.; Shipley, M.J.; Teumer, A.; Chouraki, V.; Lent, D.M. van; Tynkkynen, J.; Fischer, K.; Hernesniemi, J.; Haller, T.; Singh-Manoux, A.; Verhoeven, A.; Willemsen, G.; Leeuw, F.A. de; Wagner, H.; Dongen, J. van; Hertel, J.; Budde, K.; Dijk, K.W. van; Weinhold, L.; Ikram, M.A.; Pietzner, M.; Perola, M.; Wagner, M.; Friedrich, N.; Slagboom, P.E.; Scheltens, P.; Yang, Q.; Gertzen, R.E.; Egert, S.; Li, S.; Hankemeier, T.; Beijsterveldt, C.E.M. van; Vasan, R.S.; Maier, W.; Peeters, C.F.W.; Grabe, H.J.; Ramirez, A.; Seshadri, S.; Metspalu, A.; Kivimaki, M.; Salomaa, V.; Demirkan, A.; Boomsma, D.I.; Flier, W.M. van der; Amin, N. & Duijn, C.M. van (2018), Circulating metabolites and general cognitive ability and dementia: Evidence from 11 cohort studies, Alzheimer's and Dementia 14(6): 707-722.
- Odintsova, V.V.; Willemsen, G.; Dolan, C.V.; Hottenga, J.J.; Martin, N.G.; Slagboom, P.E.; Ordonana, J.R. & Boomsma, D.I. (2018), Establishing a Twin Register: An Invaluable Resource for (Behavior) Genetic, Epidemiological, Biomarker, and "Omics' Studies, Twin Research and Human Genetics 21(3): 239-252.
- Noordam, R.; Huurman, N.C.; Wijsman, C.A.; Akintola, A.A.; Jansen, S.W.M.; Stassen, S.; Beekman, M.; Rest, O. van de; Slagboom, P.E.; Mooijaart, S.P. & Heemst, D. van (2018), High Adiposity Is Associated With Higher Nocturnal and Diurnal Glycaemia, but Not With Glycemic Variability in Older Individuals Without Diabetes, Frontiers in Endocrinology 9.
- van Hoolwerff M., Ramos Y. F., Lakenberg N., Kloppenburg M., Ye K., Lameijer E. -W. E., Nelissen R. G., Slagboom P. & Meulenbelt I. (2018), IDENTIFICATION OF A HIGH IMPACT MUTATION IN THE FN1 GENE IN EARLY-ONSET OSTEOARTHRITIS FAMILY, Osteoarthritis and Cartilage 26: S97-S97.
- Almeida R. C., Ramos Y., Mahfouz A., Houtman E., Lakenberg N., Kloppenburg G., Slagboom P., Nelissen R. G., Reinders M. & Meulenbelt I. (2018), INTEGRATIVE APPROACH UNCOVER MICRORNA INTERACTOME DYSREGULATION IN OSTEOARTHRITIS CARTILAGE, Osteoarthritis and Cartilage 26: S162-S162.
- van den Munckhof Inge C., Kurilshikov Alexander, Bonder Marc J., Schraa Kiki, Rutten Joost H., Riksen Niels P., de Graaf Jacqueline, Oosting Marije, Joosten Leo A., Koonen Debby, Slagboom Eline P., Xavier Ramnik J., Kuipers Folkert, Hofker Marten H., Wijmenga Cisca, Netea Mihai G., Zhernakova Alexandra & Fu Jingyuan (2018), MICROBIAL IMPACT ON PLASMA METABOLITES IS LINKED TO THE CARDIOVASCULAR RISK AND PHENOTYPES, Atherosclerosis. Supplements 32: 118-119.
- Ramos Y. F., Sentner T., de Almeida R. Coutinho, den Hollander W., Meessen J., Houtman E., Heutink K., Lakenberg N., Slagboom P., Nelissen R. G. & Meulenbelt I. (2018), OSTEOARTHRITIS SUBTYPES SHOW DISTINGUISHED TRANSCRIPTOMIC LANDSCAPES, Osteoarthritis and Cartilage 26: S155-S156.
- Davies, G.; Lam, M.; Harris, S.E.; Trampush, J.W.; Luciano, M.; Hill, W.D.; Hagenaars, S.P.; Ritchie, S.J.; Marioni, R.E.; Fawns-Ritchie, C.; Liewald, D.C.M.; Okely, J.A.; Ahola-Olli, A.V.; Barnes, C.L.K.; Bertram, L.; Bis, J.C.; Burdick, K.E.; Christoforou, A.; DeRosse, P.; Djurovic, S.; Espeseth, T.; Giakoumaki, S.; Giddaluru, S.; Gustavson, D.E.; Hayward, C.; Hofer, E.; Ikram, M.A.; Karlsson, R.; Knowles, E.; Lahti, J.; Leber, M.; Li, S.; Mather, K.A.; Melle, I.; Morris, D.; Oldmeadow, C.; Palviainen, T.; Payton, A.; Pazoki, R.; Petrovic, K.; Reynolds, C.A.; Sargurupremraj, M.; Scholz, M.; Smith, J.A.; Smith, A.V.; Terzikhan, N.; Thalamuthu, A.; Trompet, S.; Lee, S.J.D.; Ware, E.B.; Windham, B.G.; Wright, M.J.; Yang, J.; Yu, J.; Ames, D.; Amin, N.; Amouyel, P.; Andreassen, O.A.; Armstrong, N.J.; Assareh, A.A.; Attia, J.R.; Attix, D.; Avramopoulos, D.; Bennett, D.A.; Boehmer, A.C.; Boyle, P.A.; Brodaty, H.; Campbell, H.; Cannon, T.D.; Cirulli, E.T.; Congdon, E.; Conley, E.D.; Corley, J.; Cox, S.R.; Dale, A.M.; Dehghan, A.; Dick, D.; Dickinson, D.; Eriksson, J.G.; Evangelou, E.; Faul, J.D.; Ford, I.; Freimer, N.A.; Gao, H.; Giegling, I.; Gillespie, N.A.; Gordon, S.D.; Gottesman, R.F.; Griswold, M.E.; Gudnason, V.; Harris, T.B.; Hartmann, A.M.; Hatzimanolis, A.; Heiss, G.; Holliday, E.G.; Joshi, P.K.; Kahonen, M.; Kardia, S.L.R.; Karlsson, I.; Kleineidam, L.; Knopman, D.S.; Kochan, N.A.; Konte, B.; Kwok, J.B.; Hellard, S.; Lee, T.; Lehtimaki, T.; Li, S.C.; Liu, T.; Koini, M.; London, E.; LongstrethJr, W.T.; Lopez, O.L.; Loukola, A.; Luck, T.; Lundervold, A.J.; Lundquist, A.; Lyytikainen, L.P.; Martin, N.G.; Montgomery, G.W.; Murray, A.D.; Need, A.C.; Noordam, R.; Nyberg, L.; Ollier, W.; Papenberg, G.; Pattie, A.; Polasek, O.; Poldrack, R.A.; Psaty, B.M.; Reppermund, S.; Riedel-Heller, S.G.; Rose, R.J.; Rotter, J.I.; Roussos, P.; Rovio, S.P.; Saba, Y.; Sabb, F.W.; Sachdev, P.S.; Satizabal, C.L.; Schmid, M.; Scott, R.J.; Scult, M.A.; Simino, J.; Slagboom, P.E.; Smyrnis, N.; Soumare, A.; Stefanis, N.C.; Stott, D.J.; Straub, R.E.; Sundet, K.; Taylor, A.M.; Taylor, K.D.; Tzoulaki, I.; Tzourio, C.; Uitterlinden, A.; Vitart, V.; Voineskos, A.N.; Kaprio, J.; Wagner, M.; Wagner, H.; Weinhold, L.; Wen, K.H.; Widen, E.; Yang, Q.; Zhao, W.; Adams, H.H.H.; Arking, D.E.; Bilder, R.M.; Bitsios, P.; Boerwinkle, E.; Chiba-Falek, O.; Corvin, A.; Jager, P.L.; Debette, S.; Donohoe, G.; Elliott, P.; Fitzpatrick, A.L.; Gill, M.; Glahn, D.C.; Hagg, S.; Hansell, N.K.; Hariri, A.R.; Ikram, M.K.; Jukema, J.W.; Vuoksimaa, E.; Keller, M.C.; Kremen, W.S.; Launer, L.; Lindenberger, U.; Palotie, A.; Pedersen, N.L.; Pendleton, N.; Porteous, D.J.; Raikkonen, K.; Raitakari, O.T.; Ramirez, A.; Reinvang, I.; Rudan, I.; Rujescu, D.; Schmidt, R.; Schmidt, H.; Schofield, P.W.; Schofield, P.R.; Starr, J.M.; Steen, V.M.; Trollor, J.N.; Turner, S.T.; Duijn, C.M.; Villringer, A.; Weinberger, D.R.; Weir, D.R.; Wilson, J.F.; Malhotra, A.; McIntosh, A.M.; Gale, C.R.; Seshadri, S.; MosleyJr, T.H.; Bressler, J.; Lencz, T. & Deary, I.J. (2018), Study of 300,486 individuals identifies 148 independent genetic loci influencing general cognitive function, Nature Communications 9.
- Rodriguez-Girondo, M.; Deelen, J.; Slagboom, E.P. & Houwing-Duistermaat, J.J. (2018), Survival analysis with delayed entry in selected families with application to human longevity, Statistical Methods in Medical Research 27(3): 933-954.
- Bas-Hoogendam, J.M.; Harrewijn, A.; Tissier, R.L.M.; Molen, M.J.W. van der; Steenbergen, H. van; Vliet, I.M. van; Reichart, C.G.; Houwing-Duistermaat, J.J.; Slagboom, P.E.; Wee, N.J.A. van der & Westenberg, P.M. (2018), The Leiden Family Lab study on Social Anxiety Disorder: A multiplex, multigenerational family study on neurocognitive endophenotypes, International Journal of Methods in Psychiatric Research 27(2).
- Smit, R.A.J.; Jukema, J.W.; Postmus, I.; Ford, I.; Slagboom, P.E.; Heijmans, B.T.; Cessie, S. le & Trompet, S. (2018), Visit-to-visit lipid variability: Clinical significance, effects of lipid-lowering treatment, and (pharmaco) genetics, Journal of Clinical Lipidology 12(2): 266-276.
- Giacconi, R.; Costarelli, L.; Piacenza, F.; Basso, A.; Burkle, A.; Moreno-Villanueva, M.; Grune, T.; Weber, D.; Stuetz, W.; Gonos, E.S.; Schon, C.; Grubeck-Loebenstein, B.; Sikora, E.; Toussaint, O.; Debacq-Chainiaux, F.; Franceschi, C.; Hervonen, A.; Slagboom, E.; Ciccarone, F.; Zampieri, M.; Caiafa, P.; Jansen, E.; Dolle, M.E.T.; Breusing, N.; Mocchegiani, E. & Malavolta, M. (2018), Zinc-Induced Metallothionein in Centenarian Offspring From a Large European Population: The MARK-AGE Project, Journals of Gerontology, Series A 73(6): 745-753.
- Jiang, X.; O'Reilly, P.F.; Aschard, H.; Hsu, Y.H.; Richards, J.B.; Dupuis, J.; Ingelsson, E.; Karasik, D.; Pilz, S.; Berry, D.; Kestenbaum, B.; Zheng, J.S.; Luan, J.N.; Sofianopoulou, E.; Streeten, E.A.; Albanes, D.; Lutsey, P.L.; Yao, L.; Tang, W.H.; Econs, M.J.; Wallaschofski, H.; Volzke, H.; Zhou, A.; Power, C.; McCarthy, M.I.; Michos, E.D.; Boerwinkle, E.; Weinstein, S.J.; Freedman, N.D.; Huang, W.Y.; Schoor, N.M. van; Velde, N. van der; Groot, L.C.P.G.M. de; Enneman, A.; Cupples, L.A.; Booth, S.L.; Vasan, R.S.; Liu, C.T.; Zhou, Y.H.; Ripatti, S.; Ohlsson, C.; Vandenput, L.; Lorentzon, M.; Eriksson, J.G.; Shea, M.K.; Houston, D.K.; Kritchevsky, S.B.; Liu, Y.M.; Lohman, K.K.; Ferrucci, L.; Peacock, M.; Gieger, C.; Beekman, M.; Slagboom, E.; Deelen, J.; Heemst, D. van; Kleber, M.E.; Marz, W.; Boer, I.H. de; Wood, A.C.; Rotter, J.I.; Rich, S.S.; Robinson-Cohen, C.; Heijer, M. den; Jarvelin, M.R.; Cavadino, A.; Joshi, P.K.; Wilson, J.F.; Hayward, C.; Lind, L.; Michaelsson, K.; Trompet, S.; Zillikens, M.C.; Uitterlinden, A.G.; Rivadeneira, F.; Broer, L.; Zgaga, L.; Campbell, H.; Theodoratou, E.; Farrington, S.M.; Timofeeva, M.; Dunlop, M.G.; Valdes, A.M.; Tikkanen, E.; Lehtimaki, T.; Lyytikainen, L.P.; Kahonen, M.; Raitakari, O.T.; Mikkila, V.; Ikram, M.A.; Sattar, N.; Jukema, J.W.; Wareham, N.J.; Langenberg, C.; Forouhi, N.G.; Gundersen, T.E.; Khaw, K.T.; Butterworth, A.S.; Danesh, J.; Spector, T.; Wang, T.J.; Hypponen, E.; Kraft, P. & Kiel, D.P. (2018), Genome-wide association study in 79,366 European-ancestry individuals informs the genetic architecture of 25-hydroxyvitamin D levels, Nature Communications 9.
- Molnos, S.; Wahl, S.; Haid, M.; Eekhoff, E.M.W.; Pool, R.; Floegel, A.; Deelen, J.; Much, D.; Prehn, C.; Breier, M.; Draisma, H.H.; Leeuwen, N. van; Simonis-Bik, A.M.C.; Jonsson, A.; Willemsen, G.; Bernigau, W.; Wang-Sattler, R.; Suhre, K.; Peters, A.; Thorand, B.; Herder, C.; Rathmann, W.; Roden, M.; Gieger, C.; Kramer, M.H.H.; Heemst, D. van; Pedersen, H.K.; Gudmundsdottir, V.; Schulze, M.B.; Pischon, T.; Geus, E.J.C. de; Boeing, H.; Boomsma, D.I.; Ziegler, A.G.; Slagboom, P.E.; Hummel, S.; Beekman, M.; Grallert, H.; Brunak, S.; McCarthy, M.I.; Gupta, R.; Pearson, E.R.; Adamski, J. & Hart, L.M. 't (2018), Metabolite ratios as potential biomarkers for type 2 diabetes: a DIRECT study, Diabetologia 61(1): 117-129.
- Hillger J.M., Roy B. le, Wang Z., Mulder-Krieger T., Boomsma D.I., Slagboom P.E., Danen E.H.J., IJzerman A.P. & Heitman L.H. (2017), Phenotypic screening of cannabinoid receptor 2 ligands shows different sensitivity to genotype, Biochemical Pharmacology 130: 60-70.
- Schoenmaker, M.; Craen, A.J.M. de; Meijer, P.H.E.M. de; Beekman, M.; Blauw, G.J.; Slagboom, P.E. & Westendorp, R.G.J. (2017), Evidence of genetic enrichment for exceptional survival using a family approach: the Leiden Longevity Study (Reprinted from EUROPEAN JOURNAL OF HUMAN GENETICS, vol 13, pg 1025-1032, 2005), European Journal of Human Genetics 25: S91-S94.
- Vliet, N.A. van; Spoel, E. van der; Beekman, M.; Slagboom, P.E.; Blauw, G.J.; Gussekloo, J.; Westendorp, R.G.J. & Heemst, D. van (2017), Thyroid status and mortality in nonagenarians from long-lived families and the general population, Aging 9(10): 2220-+.
- Ben-Avraham, D.; Karasik, D.; Verghese, J.; Lunetta, K.L.; Smith, J.A.; Eicher, J.D.; Vered, R.; Deelen, J.; Arnold, A.M.; Buchman, A.S.; Tanaka, T.; Faul, J.D.; Nethander, M.; Fornage, M.; Adams, H.H.; Matteini, A.M.; Callisaya, M.L.; Smith, A.V.; Yu, L.; Jager, P.L. de; Evans, D.A.; Gudnason, V.; Hofman, A.; Pattie, A.; Corley, J.; Launer, L.J.; Knopman, D.S.; Parimi, N.; Turner, S.T.; Bandinelli, S.; Beekman, M.; Gutman, D.; Sharvit, L.; Mooijaart, S.P.; Liewald, D.C.; Houwing-Duistermaat, J.J.; Ohlsson, C.; Moed, M.; Verlinden, V.J.; Mellstrom, D.; Geest, J.N. van der; Karlsson, M.; Hernandez, D.; McWhirter, R.; Liu, Y.M.; Thomson, R.; Tranah, G.J.; Uitterlinden, A.G.; Weir, D.R.; Zhao, W.; Starr, J.M.; Johnson, A.D.; Ikram, M.A.; Bennett, D.A.; Cummings, S.R.; Deary, I.J.; Harris, T.B.; Kardia, S.L.R.; Mosley, T.H.; Srikanth, V.K.; Windham, B.G.; Newman, A.B.; Walston, J.D.; Davies, G.; Evans, D.S.; Slagboom, E.P.; Ferrucci, L.; Kiel, D.P.; Murabito, J.M. & Atzmon, G. (2017), The complex genetics of gait speed: genome-wide meta-analysis approach (vol 9, pg 209, 2017), Aging 9(7): 1844-1846.
- Tiku, V.; Jain, C.; Raz, Y.; Nakamura, S.; Heestand, B.; Liu, W.; Spath, M.; Suchiman, H.E.D.; Muller, R.U.; Slagboom, P.E.; Partridge, L. & Antebi, A. (2017), Small nucleoli are a cellular hallmark of longevity, Nature Communications 8.
- Noordam, R.; Hamer, M.A.; Pardo, L.M.; Nat, T. van der; Kiefte-de Jong, J.C.; Kayser, M.; Slagboom, P.E.; Uitterlinden, A.; Zillikens, M.C.; Beekman, M.; Nijsten, T.; Heemst, D. van & Gunn, D.A. (2017), No Causal Association between 25-Hydroxyvitamin D and Features of Skin Aging: Evidence from a Bidirectional Mendelian Randomization Study, Journal of Investigative Dermatology 137(11): 2291-2297.
- Berg, N. van den; Beekman, M.; Smith, K.R.; Janssens, A. & Slagboom, P.E. (2017), Historical demography and longevity genetics: Back to the future, Ageing Research Reviews 38: 28-39.
- Noordam, R.; Vermond, D.; Drenth, H.; Wijman, C.A.; Akintola, A.A.; Kroef, S. van der; Jansen, S.W.M.; Huurman, N.C.; Schutte, B.A.M.; Beekman, M.; Slagboom, P.E.; Mooijaart, S.P. & Heemst, D. van (2017), High Liver Enzyme Concentrations are Associated with Higher Glycemia, but not with Glycemia Variability, in Individuals without Diabetes Mellitus, Frontiers in Endocrinology 8.
- Joshi, P.K.; Pirastu, N.; Kentistou, K.A.; Fischer, K.; Hofer, E.; Schraut, K.E.; Clark, D.W.; Nutile, T.; Barnes, C.L.K.; Timmers, P.R.H.J.; Shen, X.; Gandin, I.; McDaid, A.F.; Hansen, T.F.; Gordon, S.D.; Giulianini, F.; Boutin, T.S.; Abdellaoui, A.; Zhao, W.; Medina-Gomez, C.; Bartz, T.M.; Trompet, S.; Lange, L.A.; Raffield, L.; Spek, A. van der; Galesloot, T.E.; Proitsi, P.; Yanek, L.R.; Bielak, L.F.; Payton, A.; Murgia, F.; Concas, M.P.; Biino, G.; Tajuddin, S.M.; Seppala, I.; Amin, N.; Boerwinkle, E.; Borglum, A.D.; Campbell, A.; Demerath, E.W.; Demuth, I.; Faul, J.D.; Ford, I.; Gialluisi, A.; Gogele, M.; Graff, M.; Hingorani, A.; Hottenga, J.J.; Hougaard, D.M.; Hurme, M.A.; Ikram, M.A.; Jylha, M.; Kuh, D.; Ligthart, L.; Lill, C.M.; Lindenberger, U.; Lumley, T.; Magi, R.; Marques-Vidal, P.; Medland, S.E.; Milani, L.; Nagy, R.; Ollier, W.E.R.; Peyser, P.A.; Pramstaller, P.P.; Ridker, P.M.; Rivadeneira, F.; Ruggiero, D.; Saba, Y.; Schmidt, R.; Schmidt, H.; Slagboom, P.E.; Smith, B.H.; Smith, J.A.; Sotoodehnia, N.; Steinhagen-Thiessen, E.; Rooij, F.J.A. van; Verbeek, A.L.; Vermeulen, S.H.; Vollenweider, P.; Wang, Y.P.; Werge, T.; Whitfield, J.B.; Zonderman, A.B.; Lehtimaki, T.; Evans, M.K.; Pirastu, M.; Fuchsberger, C.; Bertram, L.; Pendleton, N.; Kardia, S.L.R.; Ciullo, M.; Becker, D.M.; Wong, A.; Psaty, B.M.; Duijn, C.M. van; Wilson, J.G.; Jukema, J.W.; Kiemeney, L.; Uitterlinden, A.G.; Franceschini, N.; North, K.E.; Weir, D.R.; Metspalu, A.; Boomsma, D.I.; Hayward, C.; Chasman, D.; Martin, N.G.; Sattar, N.; Campbell, H.; Esko, T.; Kutalik, Z. & Wilson, J.F. (2017), Genome-wide meta-analysis associates HLA-DQA1/DRB1 and LPA and lifestyle factors with human longevity, Nature Communications 8.
- Mandaviya, P.R.; Joehanes, R.; Aissi, D.; Kuhnel, B.; Marioni, R.E.; Truong, V.; Stolk, L.; Beekman, M.; Bonder, M.J.; Franke, L.; Gieger, C.; Huan, T.X.; Ikram, M.A.; Kunze, S.; Liang, L.M.; Lindemann, J.; Liu, C.Y.; Mcrae, A.F.; Mendelson, M.M.; Muller-Nurasyid, M.; Peters, A.; Slagboom, P.E.; Starr, J.M.; Tregouet, D.A.; Uitterlinden, A.G.; Greevenbroek, M.M.J. van; Heemst, D. van; Iterson, M. van; Wells, P.S.; Yao, C.; Deary, I.J.; Gagnon, F.; Heijmans, B.T.; Levy, D.; Morange, P.E.; Waldenberger, M.; Heil, S.G.; Meurs, J.B.J. van & Charge Consortium Epigenetics Grp (2017), Genetically defined elevated homocysteine levels do not result in widespread changes of DNA methylation in leukocytes, PLoS ONE 12(10).
- Raz, Y.; Guerrero-Ros, I.; Maier, A.; Slagboom, P.E.; Atzmon, G.; Barzilai, N. & Macian, F. (2017), Activation-Induced Autophagy Is Preserved in CD4(+)T-Cells in Familial Longevity, Journals of Gerontology, Series A 72(9): 1201-1206.
- Mandaviya, P.R.; Aissi, D.; Dekkers, K.F.; Joehanes, R.; Kasela, S.; Truong, V.; Stolk, L.; Heemst, D. van; Ikram, M.A.; Lindemans, J.; Slagboom, P.E.; Tregouet, D.A.; Uitterlinden, A.G.; Wei, C.; Wells, P.; Gagnon, F.; Greevenbroek, M.M.J. van; Heijmans, B.T.; Milani, L.; Morange, P.E.; Meurs, J.B.J. van; Heil, S.G. & BIOS Consortium (2017), Homocysteine levels associate with subtle changes in leukocyte DNA methylation: an epigenome-wide analysis, Epigenomics 9(11): 1403-1422.
- Hollander, W. den; Boer, C.G.; Hart, D.J.; Yau, M.S.; Ramos, Y.F.M.; Metrustry, S.; Broer, L.; Deelen, J.; Cupples, L.A.; Rivadeneira, F.; Kloppenburg, M.; Peters, M.; Spector, T.D.; Hofman, A.; Slagboom, P.E.; Nelissen, R.G.H.H.; Uitterlinden, A.G.; Felson, D.T.; Valdes, A.M.; Meulenbelt, I. & Meurs, J.J.B. van (2017), Genome-wide association and functional studies identify a role for matrix Gla protein in osteoarthritis of the hand, Annals of the Rheumatic Diseases 76(12): 2046-2053.
- Ben-Avraham, D.; Karasik, D.; Verghese, J.; Lunetta, K.L.; Smith, J.A.; Eicher, J.D.; Vered, R.; Deelen, J.; Arnold, A.M.; Buchman, A.S.; Tanaka, T.; Faul, J.D.; Nethander, M.; Fornage, M.; Adams, H.H.; Matteini, A.M.; Callisaya, M.L.; Smith, A.V.; Yu, L.; Jager, P.L. de; Evans, D.A.; Gudnason, V.; Hofman, A.; Pattie, A.; Corley, J.; Launer, L.J.; Knopman, D.S.; Parimi, N.; Turner, S.T.; Bandinelli, S.; Beekman, M.; Gutman, D.; Sharvit, L.; Mooijaart, S.P.; Liewald, D.C.; Houwing-Duistermaat, J.J.; Ohlsson, C.; Moed, M.; Verlinden, V.J.; Mellstrom, D.; Geest, J.N. van der; Karlsson, M.; Hernandez, D.; McWhirter, R.; Liu, Y.M.; Thomson, R.; Tranah, G.J.; Uitterlinden, A.G.; Weir, D.R.; Zhao, W.; Starr, J.M.; Johnson, A.D.; Ikram, M.A.; Bennett, D.A.; Cummings, S.R.; Deary, I.J.; Harris, T.B.; Kardia, S.L.R.; Mosley, T.H.; Srikanth, V.K.; Windham, B.G.; Newman, A.B.; Walston, J.D.; Davies, G.; Evans, D.S.; Slagboom, E.P.; Ferrucci, L.; Kiel, D.P.; Murabito, J.M. & Atzmon, G. (2017), The complex genetics of gait speed: genome-wide meta-analysis approach, Aging 9(1): 209-246.
- Bacalini, M.G.; Deelen, J.; Pirazzini, C.; Cecco, M. de; Giuliani, C.; Lanzarini, C.; Ravaioli, F.; Marasco, E.; Heemst, D. van; Suchiman, H.E.D.; Slieker, R.; Giampieri, E.; Recchioni, R.; Marcheselli, F.; Salvioli, S.; Vitale, G.; Olivieri, F.; Spijkerman, A.M.W.; Dolle, M.E.T.; Sedivy, J.M.; Castellani, G.; Franceschi, C.; Slagboom, P.E. & Garagnani, P. (2017), Systemic Age-Associated DNA Hypermethylation of ELOVL2 Gene: In Vivo and In Vitro Evidences of a Cell Replication Process, Journals of Gerontology, Series A 72(8): 1015-1023.
- Hagg, S.; Zhan, Y.; Karlsson, R.; Gerritsen, L.; Ploner, A.; Lee, S.J. van der; Broer, L.; Deelen, J.; Marioni, R.E.; Wong, A.; Lundquist, A.; Zhu, G.; Hansell, N.K.; Sillanpaa, E.; Fedko, I.O.; Amin, N.A.; Beekman, M.; Craen, A.J.M. de; Degerman, S.; Harris, S.E.; Kan, K.J.; Martin-Ruiz, C.M.; Montgomery, G.W.; Adolfsson, A.N.; Reynolds, C.A.; Samani, N.J.; Suchiman, H.E.D.; Viljanen, A.; Zglinicki, T. von; Wright, M.J.; Hottenga, J.J.; Boomsma, D.I.; Rantanen, T.; Kaprio, J.A.; Nyholt, D.R.; Martin, N.G.; Nyberg, L.; Adolfsson, R.; Kuh, D.; Starr, J.M.; Deary, I.J.; Slagboom, P.E.; Duijn, C.M. van; Codd, V.; Pedersen, N.L.; NeuroCHARGE Cognitive Working Grp & ENGAGE Consortium (2017), Short telomere length is associated with impaired cognitive performance in European ancestry cohorts, Translational Psychiatry 7.
- Hillger, J.M.; Roy, B. le; Wang, Z.; Mulder-Krieger, T.; Boomsma, D.I.; Slagboom, P.E.; Danen, E.H.J.; Ijzerman, A.P. & Heitman, L.H. (2017), Phenotypic screening of cannabinoid receptor 2 ligands shows different sensitivity to genotype, Biochemical Pharmacology 130: 60-70.
- Justice, A.E.; Winkler, T.W.; Feitosa, M.F.; Graff, M.; Fisher, V.A.; Young, K.; Barata, L.; Deng, X.; Czajkowski, J.; Hadley, D.; Ngwa, J.S.; Ahluwalia, T.S.; Chu, A.Y.; Heard-Costa, N.L.; Lim, E.; Perez, J.; Eicher, J.D.; Kutalik, Z.; Xue, L.; Mahajan, A.; Renstrom, F.; Wu, J.; Qi, Q.B.; Ahmad, S.; Alfred, T.; Amin, N.; Bielak, L.F.; Bonnefond, A.; Bragg, J.; Cadby, G.; Chittani, M.; Coggeshall, S.; Corre, T.; Direk, N.; Eriksson, J.; Fischer, K.; Gorski, M.; Harder, M.N.; Horikoshi, M.; Huang, T.; Huffman, J.E.; Jackson, A.U.; Justesen, J.M.; Kanoni, S.; Kinnunen, L.; Kleber, M.E.; Komulainen, P.; Kumari, M.; Lim, U.; Luan, J.; Lyytikainen, L.P.; Mangino, M.; Manichaikul, A.; Marten, J.; Middelberg, R.P.S.; Mueller-Nurasyid, M.; Navarro, P.; Perusse, L.; Pervjakova, N.; Sarti, C.; Smith, A.V.; Smith, J.A.; Stancakova, A.; Strawbridge, R.J.; Stringham, H.M.; Sung, Y.J.; Tanaka, T.; Teumer, A.; Trompet, S.; Laan, S.W. van der; Most, P.J. van der; Vliet-Ostaptchouk, J.V. van; Vedantam, S.L.; Verweij, N.; Vink, J.M.; Vitart, V.; Wu, Y.; Yengo, L.; Zhang, W.H.; Zhao, J.H.; Zimmermann, M.E.; Zubair, N.; Abecasis, G.R.; Adair, L.S.; Afaq, S.; Afzal, U.; Bakker, S.J.L.; Bartz, T.M.; Beilby, J.; Bergman, R.N.; Bergmann, S.; Biffar, R.; Blangero, J.; Boerwinkle, E.; Bonnycastle, L.L.; Bottinger, E.; Braga, D.; Buckley, B.M.; Buyske, S.; Campbell, H.; Chambers, J.C.; Collins, F.S.; Curran, J.E.; Borst, G.J. de; Craen, A.J.M. de; Geus, E.J.C. de; Dedoussis, G.; Delgado, G.E.; Ruijter, H.M. den; Eiriksdottir, G.; Eriksson, A.L.; Esko, T.; Faul, J.D.; Ford, I.; Forrester, T.; Gertow, K.; Gigante, B.; Glorioso, N.; Gong, J.; Grallert, H.; Grammer, T.B.; Grarup, N.; Haitjema, S.; Hallmans, G.; Hamsten, A.; Hansen, T.; Harris, T.B.; Hartman, C.A.; Hassinen, M.; Hastie, N.D.; Heath, A.C.; Hernandez, D.; Hindorff, L.; Hocking, L.J.; Hollensted, M.; Holmen, O.L.; Homuth, G.; Hottenga, J.J.; Huang, J.; Hung, J.; Hutri-Kahonen, N.; Ingelsson, E.; James, A.L.; Jansson, J.O.; Jarvelin, M.R.; Jhun, M.A.; Jorgensen, M.E.; Juonala, M.; Kahonen, M.; Karlsson, M.; Koistinen, H.A.; Kolcic, I.; Kolovou, G.; Kooperberg, C.; Kramer, B.K.; Kuusisto, J.; Kvaloy, K.; Lakka, T.A.; Langenberg, C.; Launer, L.J.; Leander, K.; Lee, N.R.; Lind, L.; Lindgren, C.M.; Linneberg, A.; Lobbens, S.; Loh, M.; Lorentzon, M.; Luben, R.; Lubke, G.; Ludolph-Donislawski, A.; Lupoli, S.; Madden, P.A.F.; Mannikko, R.; Marques-Vidal, P.; Martin, N.G.; McKenzie, C.A.; McKnight, B.; Mellstrom, D.; Menni, C.; Montgomery, G.W.; Musk, A.W.; Narisu, N.; Nauck, M.; Nolte, I.M.; Oldehinkel, A.J.; Olden, M.; Ong, K.K.; Padmanabhan, S.; Peyser, P.A.; Pisinger, C.; Porteous, D.J.; Raitakari, O.T.; Rankinen, T.; Rao, D.C.; Rasmussen-Torvik, L.J.; Rawal, R.; Rice, T.; Ridker, P.M.; Rose, L.M.; Bien, S.A.; Rudan, I.; Sanna, S.; Sarzynski, M.A.; Sattar, N.; Savonen, K.; Schlessinger, D.; Scholtens, S.; Schurmann, C.; Scott, R.A.; Sennblad, B.; Siemelink, M.A.; Silbernagel, G.; Slagboom, P.E.; Snieder, H.; Staessen, J.A.; Stott, D.J.; Swertz, M.A.; Swift, A.J.; Taylor, K.D.; Tayo, B.O.; Thorand, B.; Thuillier, D.; Tuomilehto, J.; Uitterlinden, A.G.; Vandenput, L.; Vohl, M.C.; Volzke, H.; Vonk, J.M.; Waeber, G.; Waldenberger, M.; Westendorp, R.G.J.; Wild, S.; Willemsen, G.; Wolffenbuttel, B.H.R.; Wong, A.; Wright, A.F.; Zhao, W.; Zillikens, M.C.; Baldassarre, D.; Balkau, B.; Bandinelli, S.; Boger, C.A.; Boomsma, D.I.; Bouchard, C.; Bruinenberg, M.; Chasman, D.I.; Chen, Y.D.I.; Chines, P.S.; Cooper, R.S.; Cucca, F.; Cusi, D.; Faire, U. de; Ferrucci, L.; Franks, P.W.; Froguel, P.; Gordon-Larsen, P.; Grabe, H.J.; Gudnason, V.; Haiman, C.A.; Hayward, C.; Hveem, K.; Johnson, A.D.; Jukema, W.; Kardia, S.L.R.; Kivimaki, M.; Kooner, J.S.; Kuh, D.; Laakso, M.; Lehtimaki, T.; Marchand, L. le; Marz, W.; McCarthy, M.I.; Metspalu, A.; Morris, A.P.; Ohlsson, C.; Palmer, L.J.; Pasterkamp, G.; Pedersen, O.; Peters, A.; Peters, U.; Polasek, O.; Psaty, B.M.; Qi, L. & (2017), Genome-wide meta-analysis of 241,258 adults accounting for smoking behaviour identifies novel loci for obesity traits, Nature Communications 8.
- Berg, R. van den; Noordam, R.; Kooijman, S.; Jansen, S.W.M.; Akintola, A.A.; Slagboom, P.E.; Pijl, H.; Rensen, P.C.N.; Biermasz, N.R. & Heemst, D. van (2017), Familial longevity is characterized by high circadian rhythmicity of serum cholesterol in healthy elderly individuals, Aging Cell 16(2): 237-243.
- Verhoeven, A.; Slagboom, E.; Wuhrer, M.; Giera, M. & Mayboroda, O.A. (2017), Automated quantification of metabolites in blood-derived samples by NMR, Analytica Chimica Acta 976: 52-62.
- Waaijer, M.E.C.; Westendorp, R.G.J.; Goldeck, D.; Gunn, D.A.; Pawelec, G.; Stijntjes, M.; Slagboom, P.E. & Maier, A.B. (2017), Assessment of health status by molecular measures in adults ranging from middle-aged to old: Ready for clinical use?, Experimental Gerontology 87: 175-181.
- Noordam, R.; Sitlani, C.M.; Avery, C.L.; Stewart, J.D.; Gogarten, S.M.; Wiggins, K.L.; Trompet, S.; Warren, H.R.; Sun, F.G.; Evans, D.S.; Li, X.H.; Li, J.; Smith, A.V.; Bis, J.C.; Brody, J.A.; Busch, E.L.; Caulfield, M.J.; Chen, Y.D.I.; Cummings, S.R.; Cupples, L.A.; Duan, Q.; Franco, O.H.; Mendez-Giraldez, R.; Harris, T.B.; Heckbert, S.R.; Heemst, D. van; Hofman, A.; Floyd, J.S.; Kors, J.A.; Launer, L.J.; Li, Y.; Li-Gao, R.F.; Lange, L.A.; Lin, H.J.; Mutsert, R. de; Napier, M.D.; Newton-Cheh, C.; Poulter, N.; Reiner, A.P.; Rice, K.M.; Roach, J.; Rodriguez, C.J.; Rosendaal, F.R.; Sattar, N.; Sever, P.; Seyerle, A.A.; Slagboom, P.E.; Soliman, E.Z.; Sotoodehnia, N.; Stott, D.J.; Stumer, T.; Taylor, K.D.; Thornton, T.A.; Uitterlinden, A.G.; Wilhelmsen, K.C.; Wilson, J.G.; Gudnason, V.; Jukema, J.W.; Laurie, C.C.; Liu, Y.; Mook-Kanamori, D.O.; Munroe, P.B.; Rotter, J.I.; Vasan, R.S.; Psaty, B.M.; Stricker, B.H. & Whitsel, E.A. (2017), A genome-wide interaction analysis of tricyclic/tetracyclic antidepressants and RR and QT intervals: a pharmacogenomics study from the Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) consortium, Journal of Medical Genetics 54(5): 313-323.
- Raz Y (2017), Activation-Induced Autophagy Is Preserved in CD4+ T-Cells in Familial Longevity, The Journals of Gerontology: Series A.
- Rooij, F.J.A. van; Qayyum, R.; Smith, A.V.; Zhou, Y.; Trompet, S.; Tanaka, T.; Keller, M.F.; Chang, L.C.; Schmidt, H.; Yang, M.L.; Chen, M.H.; Hayes, J.; Johnson, A.D.; Yanek, L.R.; Mueller, C.; Lange, L.; Floyd, J.S.; Ghanbari, M.; Zonderman, A.B.; Jukema, J.W.; Hofman, A.; Duijn, C.M. van; Desch, K.C.; Saba, Y.; Ozel, A.B.; Snively, B.M.; Wu, J.Y.; Schmidt, R.; Fornage, M.; Klein, R.J.; Fox, C.S.; Matsuda, K.; Kamatani, N.; Wild, P.S.; Stott, D.J.; Ford, I.; Slagboom, P.E.; Yang, J.; Chu, A.Y.; Lambert, A.J.; Uitterlinden, A.G.; Franco, O.H.; Hofer, E.; Ginsburg, D.; Hu, B.; Keating, B.; Schick, U.M.; Brody, J.A.; Li, J.Z.; Chen, Z.; Zeller, T.; Guralnik, J.M.; Chasman, D.I.; Peters, L.L.; Kubo, M.; Becker, D.M.; Li, J.; Eiriksdottir, G.; Rotter, J.I.; Levy, D.; Grossmann, V.; Patel, K.V.; Chen, C.H.; Ridker, P.M.; Tang, H.; Launer, L.J.; Rice, K.M.; Li-Gao, R.; Ferrucci, L.; Evans, M.K.; Choudhuri, A.; Trompouki, E.; Abraham, B.J.; Yang, S.; Takahashi, A.; Kamatani, Y.; Kooperberg, C.; Harris, T.B.; Jee, S.H.; Coresh, J.; Tsai, F.J.; Longo, D.L.; Chen, Y.T.; Felix, J.F.; Yang, Q.; Psaty, B.M.; Boerwinkle, E.; Becker, L.C.; Mook-Kanamori, D.O.; Wilson, J.G.; Gudnason, V.; O'Donnell, C.J.; Dehghan, A.; Cupples, L.A.; Nalls, M.A.; Morris, A.P.; Okada, Y.; Reiner, A.P.; Zon, L.I.; Ganesh, S.K. & BioBank Japan Project (2017), Genome-wide Trans-ethnic Meta-analysis Identifies Seven Genetic Loci Influencing Erythrocyte Traits and a Role for RBPMS in Erythropoiesis, American Journal of Human Genetics 100(1): 51-63.
- Wahl, S.; Drong, A.; Lehne, B.; Loh, M.; Scott, W.R.; Kunze, S.; Tsai, P.C.; Ried, J.S.; Zhang, W.H.; Yang, Y.W.; Tan, S.L.; Fiorito, G.; Franke, L.; Guarrera, S.; Kasela, S.; Kriebel, J.; Richmond, R.C.; Adamo, M.; Afzal, U.; Ala-Korpela, M.; Albetti, B.; Ammerpohl, O.; Apperley, J.F.; Beekman, M.; Bertazzi, P.A.; Black, S.L.; Blancher, C.; Bonder, M.J.; Brosch, M.; Carstensen-Kirberg, M.; Craen, A.J.M. de; Lusignan, S. de; Dehghan, A.; Elkalaawy, M.; Fischer, K.; Franco, O.H.; Gaunt, T.R.; Hampe, J.; Hashemi, M.; Isaacs, A.; Jenkinson, A.; Jha, S.; Kato, N.; Krogh, V.; Laffan, M.; Meisinger, C.; Meitinger, T.; Mok, Z.Y.; Motta, V.; Ng, H.K.; Nikolakopoulou, Z.; Nteliopoulos, G.; Panico, S.; Pervjakova, N.; Prokisch, H.; Rathmann, W.; Roden, M.; Rota, F.; Rozario, M.A.; Sandling, J.K.; Schafmayer, C.; Schramm, K.; Siebert, R.; Slagboom, P.E.; Soininen, P.; Stolk, L.; Strauch, K.; Tai, E.S.; Tarantini, L.; Thorand, B.; Tigchelaar, E.F.; Tumino, R.; Uitterlinden, A.G.; Duijn, C. van; Meurs, J.B.J. van; Vineis, P.; Wickremasinghe, A.R.; Wijmenga, C.; Yang, T.P.; Yuan, W.; Zhernakova, A.; Batterham, R.L.; Smith, G.D.; Deloukas, P.; Heijmans, B.T.; Herder, C.; Hofman, A.; Lindgren, C.M.; Milani, L.; Harst, P. van der; Peters, A.; Illig, T.; Relton, C.L.; Waldenberger, M.; Jarvelin, M.R.; Bollati, V.; Soong, R.; Spector, T.D.; Scott, J.; McCarthy, M.I.; Elliott, P.; Bell, J.T.; Matullo, G.; Gieger, C.; Kooner, J.S.; Grallert, H. & Chambers, J.C. (2017), Epigenome-wide association study of body mass index, and the adverse outcomes of adiposity, Nature 541(7635): 81-+.
- Plomp, R.; Ruhaak, L.R.; Uh, H.W.; Reiding, K.R.; Selman, M.; Houwing-Duistermaat, J.J.; Slagboom, P.E.; Beekman, M. & Wuhrer, M. (2017), Subclass-specific IgG glycosylation is associated with markers of inflammation and metabolic health, Scientific Reports 7.
- Hollander, W. den; Boer, C.G.; Hart, D.J.; Yau, M.S.; Ramos, Y.F.M.; Metrustry, S.; Broer, L.; Deelen, J.; Cupples, L.A.; Rivadeneira, F.; Kloppenburg, M.; Peters, M.; Spector, T.D.; Hofman, A.; Slagboom, P.E.; Nelissen, R.G.H.H.; Uitterlinden, A.G.; Felson, D.T.; Valdes, A.M.; Meulenbelt, I. & Meurs, J.J.B. van (2017), Genome-wide association and functional studies identify a role for matrix Gla protein in osteoarthritis of the hand, Annals of the Rheumatic Diseases 76(12): 2046-2053.
- Zhernakova, D.V.; Deelen, P.; Vermaat, M.; Iterson, M. van; Galen, M. van; Arindrarto, W.; Hof, P. van 't; Mei, H.L.; Dijk, F. van; Westra, H.J.; Bonder, M.J.; Rooij, J. van; Verkerk, M.; Jhamai, P.M.; Moed, M.; Kielbasa, S.M.; Bot, J.; Nooren, I.; Pool, R.; Dongen, J. van; Hottenga, J.J.; Stehouwer, C.D.A.; Kallen, C.J.H. van der; Schalkwijk, C.G.; Zhernakova, A.; Li, Y.; Tigchelaar, E.F.; Klein, N. de; Beekman, M.; Deelen, J.; Heemst, D. van; Berg, L.H. van den; Hofman, A.; Uitterlinden, A.G.; Greevenbroek, M.M.J. van; Veldink, J.H.; Boomsma, D.I.; Duijn, C.M. van; Wijmenga, C.; Slagboom, P.E.; Swertz, M.A.; Isaacs, A.; Meurs, J.B.J. van; Jansen, R.; Heijmans, B.T.; Hoen, P.A.C. 't & Franke, L. (2017), Identification of context-dependent expression quantitative trait loci in whole blood, Nature Genetics 49(1): 139-145.
- Bonder, M.J.; Luijk, R.; Zhernakova, D.V.; Moed, M.; Deelen, P.; Vermaat, M.; Iterson, M. van; Dijk, F. van; Galen, M. van; Bot, J.; Slieker, R.C.; Jhamai, P.M.; Verbiest, M.; Suchiman, H.E.D.; Verkerk, M.; Breggen, R. van der; Rooij, J. van; Lakenberg, N.; Arindrarto, W.; Kielbasa, S.M.; Jonkers, I.; Hof, P. van 't; Nooren, I.; Beekman, M.; Deelen, J.; Heemst, D. van; Zhernakova, A.; Tigchelaar, E.F.; Swertz, M.A.; Hofman, A.; Uitterlinden, A.G.; Pool, R.; Dongen, J. van; Hottenga, J.J.; Stehouwer, C.D.A.; Kallen, C.J.H. van der; Schalkwijk, C.G.; Berg, L.H. van den; Zwet, E.W. van; Mei, H.L.; Li, Y.; Lemire, M.; Hudson, T.J.; Slagboom, P.E.; Wijmenga, C.; Veldink, J.H.; Greevenbroek, M.M.J. van; Duijn, C.M. van; Boomsma, D.I.; Isaacs, A.; Jansen, R.; Meurs, J.B.J. van; Hoen, P.A.C. 't; Franke, L.; Heijmans, B.T. & BIOS Consortium (2017), Disease variants alter transcription factor levels and methylation of their binding sites, Nature Genetics 49(1): 131-138.
- Vries, P.S. de; Sabater-Lleal, M.; Chasman, D.I.; Trompet, S.; Ahluwalia, T.S.; Teumer, A.; Kleber, M.E.; Chen, M.H.; Wang, J.J.; Attia, J.R.; Marioni, R.E.; Steri, M.; Weng, L.C.; Pool, R.; Grossmann, V.; Brody, J.A.; Venturini, C.; Tanaka, T.; Rose, L.M.; Oldmeadow, C.; Mazur, J.; Basu, S.; Franberg, M.; Yang, Q.; Ligthart, S.; Hottenga, J.J.; Rumley, A.; Mulas, A.; Craen, A.J.M. de; Grotevendt, A.; Taylor, K.D.; Delgado, G.E.; Kifley, A.; Lopez, L.M.; Berentzen, T.L.; Mangino, M.; Bandinelli, S.; Morrison, A.C.; Hamsten, A.; Tofler, G.; Maat, M.P.M. de; Draisma, H.H.M.; Lowe, G.D.; Zoledziewska, M.; Sattar, N.; Lackner, K.J.; Volker, U.; McKnight, B.; Huang, J.; Holliday, E.G.; McEvoy, M.A.; Starr, J.M.; Hysi, P.G.; Hernandez, D.G.; Guan, W.H.; Rivadeneira, F.; McArdle, W.L.; Slagboom, P.E.; Zeller, T.; Psaty, B.M.; Uitterlinden, A.G.; Geus, E.J.C. de; Stott, D.J.; Binder, H.; Hofman, A.; Franco, O.H.; Rotter, J.I.; Ferrucci, L.; Spector, T.D.; Deary, I.J.; Marz, W.; Greinacher, A.; Wild, P.S.; Cucca, F.; Boomsma, D.I.; Watkins, H.; Tang, W.H.; Ridker, P.M.; Jukema, J.W.; Scott, R.J.; Mitchell, P.; Hansen, T.; O'Donnell, C.J.; Smith, N.L.; Strachan, D.P. & Dehghan, A. (2017), Comparison of HapMap and 1000 Genomes Reference Panels in a Large-Scale Genome-Wide Association Study, PLoS ONE 12(1).
- Reiding, K.R.; Ruhaak, L.R.; Uh, H.W.; Bouhaddani, S. el; Akker, E.B. van den; Plomp, R.; McDonnell, L.A.; Houwing-Duistermaat, J.J.; Slagboom, P.E.; Beekman, M. & Wuhrer, M. (2017), Human Plasma N-glycosylation as Analyzed by Matrix-Assisted Laser Desorption/Ionization-Fourier Transform Ion Cyclotron Resonance-MS Associates with Markers of Inflammation and Metabolic Health, Molecular and Cellular Proteomics 16(2): 228-242.
- Zwamborn, R.A.J.; Slieker, R.C.; Mulder, P.C.A.; Zoetemelk, I.; Verschuren, L.; Suchiman, H.E.D.; Toet, K.H.; Droog, S.; Slagboom, P.E.; Kooistra, T.; Kleemann, R. & Heijmans, B.T. (2017), Prolonged high-fat diet induces gradual and fat depot-specific DNA methylation changes in adult mice, Scientific Reports 7: 1-9.
- Wahl, S.; Drong, A.; Lehne, B.; Loh, M.; Scott, W.R.; Kunze, S.; Tsai, P.C.; Ried, J.S.; Zhang, W.H.; Yang, Y.W.; Tan, S.L.; Fiorito, G.; Franke, L.; Guarrera, S.; Kasela, S.; Kriebel, J.; Richmond, R.C.; Adamo, M.; Afzal, U.; Ala-Korpela, M.; Albetti, B.; Ammerpohl, O.; Apperley, J.F.; Beekman, M.; Bertazzi, P.A.; Black, S.L.; Blancher, C.; Bonder, M.J.; Brosch, M.; Carstensen-Kirberg, M.; Craen, A.J.M. de; Lusignan, S. de; Dehghan, A.; Elkalaawy, M.; Fischer, K.; Franco, O.H.; Gaunt, T.R.; Hampe, J.; Hashemi, M.; Isaacs, A.; Jenkinson, A.; Jha, S.; Kato, N.; Krogh, V.; Laffan, M.; Meisinger, C.; Meitinger, T.; Mok, Z.Y.; Motta, V.; Ng, H.K.; Nikolakopoulou, Z.; Nteliopoulos, G.; Panico, S.; Pervjakova, N.; Prokisch, H.; Rathmann, W.; Roden, M.; Rota, F.; Rozario, M.A.; Sandling, J.K.; Schafmayer, C.; Schramm, K.; Siebert, R.; Slagboom, P.E.; Soininen, P.; Stolk, L.; Strauch, K.; Tai, E.S.; Tarantini, L.; Thorand, B.; Tigchelaar, E.F.; Tumino, R.; Uitterlinden, A.G.; Duijn, C. van; Meurs, J.B.J. van; Vineis, P.; Wickremasinghe, A.R.; Wijmenga, C.; Yang, T.P.; Yuan, W.; Zhernakova, A.; Batterham, R.L.; Smith, G.D.; Deloukas, P.; Heijmans, B.T.; Herder, C.; Hofman, A.; Lindgren, C.M.; Milani, L.; Harst, P. van der; Peters, A.; Illig, T.; Relton, C.L.; Waldenberger, M.; Jarvelin, M.R.; Bollati, V.; Soong, R.; Spector, T.D.; Scott, J.; McCarthy, M.I.; Elliott, P.; Bell, J.T.; Matullo, G.; Gieger, C.; Kooner, J.S.; Grallert, H. & Chambers, J.C. (2017), Epigenome-wide association study of body mass index, and the adverse outcomes of adiposity, Nature 541(7635): 81-+.
- Teumer, A.; Qi, Q.; Nethander, M.; Aschard, H.; Bandinelli, S.; Beekman, M.; Berndt, S.I.; Bidlingmaier, M.; Broer, L.; Cappola, A.; Ceda, G.P.; Chanock, S.; Chen, M.H.; Chen, T.C.; Chen, Y.D.I.; Chung, J.; Miglianico, F.D.G.; Eriksson, J.; Ferrucci, L.; Friedrich, N.; Gnewuch, C.; Goodarzi, M.O.; Grarup, N.; Guo, T.; Hammer, E.; Hayes, R.B.; Hicks, A.A.; Hofman, A.; Houwing-Duistermaat, J.J.; Hu, F.; Hunter, D.J.; Husemoen, L.L.; Isaacs, A.; Jacobs, K.B.; Janssen, J.A.M.J.L.; Jansson, J.O.; Jehmlich, N.; Johnson, S.; Juul, A.; Karlsson, M.; Kilpelainen, T.O.; Kovacs, P.; Kraft, P.; Li, C.; Linneberg, A.; Liu, Y.; Loos, R.J.F.; Lorentzon, M.; Lu, Y.; Maggio, M.; Magi, R.; Meigs, J.; Mellstrom, D.; Nauck, M.; Newman, A.B.; Pollak, M.N.; Pramstaller, P.P.; Prokopenko, I.; Psaty, B.M.; Reincke, M.; Rimm, E.B.; Rotter, J.I.; Pierre, A.S.; Schurmann, C.; Seshadri, S.; Sjogren, K.; Slagboom, P.E.; Strickler, H.D.; Stumvoll, M.; Suh, Y.; Sun, Q.; Zhang, C.; Svensson, J.; Tanaka, T.; Tare, A.; Tonjes, A.; Uh, H.W.; Duijn, C.M. van; Heemst, D. van; Vandenput, L.; Vasan, R.S.; Volker, U.; Willems, S.M.; Ohlsson, C.; Wallaschofski, H.; Kaplan, R.C.; CHARGE Longevity Working Grp & Body Composition Genetics Consorti (2017), Genomewide meta-analysis identifies loci associated with IGF-I and IGEBP-3 levels with impact on age-related traits (vol 15, pg 811, 2016), Aging Cell 16(4): 898-898.
- Rest O. van de, Schutte B.A.M., Deelen J., Stassen S.A.M., Akker E.B. van de, Heemst D. van, Dibbets-Schneider P., Dipten-Van der Veen R.A. van, Kelderman M., Hankemeier T., Mooijaart S.P., Grond J. van der, Houwing-Duistermaat J.J., Beekman M., Feskens E.J.M. & Slagboom P. (2016), Metabolic effects of a 13-weeks lifestyle intervention in older adults: The Growing Old Together Study, Aging 8(1): 111-126.
- Skelton, A.J.; Hollander, W. den; Jeffries, M.; Gomez, R.; Donica, M.; Baker, L.; Lakenberg, N.; Dijcker, W. de; Slagboom, E.P.; Loughlin, J.; Meulenbelt, I. & Reynard, L.N. (2016), AGE-RELATED DNA METHYLATION CHANGES IN NORMAL AND OSTEOARTHRITIS CARTILAGE, Osteoarthritis and Cartilage 24: S41-S41.
- Bomer, N.; Cornelis, F.M.F.; Ramos, Y.F.M.; Hollander, W. den; Lakenberg, N.; Breggen, R. van der; Storms, L.; Slagboom, P.E.; Lories, R.J.U. & Meulenbelt, I. (2016), Aberrant Calreticulin Expression in Articular Cartilage of Dio2 Deficient Mice, PLoS ONE 11(5).
- Bomer, N.; Hollander, W. den; Suchiman, E.; Houtman, E.; Slieker, R.C.; Heijmans, B.T.; Slagboom, P.E.; Nelissen, R.G.; Ramos, Y.F. & Meulenbelt, I. (2016), NEO-CARTILAGE ENGINEERED FROM PRIMARY CHONDROCYTES IS EPIGENETICALLY SIMILAR TO AUTOLOGOUS CARTILAGE, IN CONTRAST TO USING MESENCHYMAL STEM CELLS, Osteoarthritis and Cartilage 24: S227-S227.
- Zeng, Y.; Nie, C.; Min, J.X.; Liu, X.M.; Li, M.M.; Chen, H.S.; Xu, H.S.; Wang, M.B.; Ni, T.; Li, Y.; Yan, H.; Zhang, J.P.; Song, C.; Chi, L.Q.; Wang, H.M.; Dong, J.; Zheng, G.Y.; Lin, L.; Qian, F.; Qi, Y.W.; Liu, X.; Cao, H.Z.; Wang, Y.H.; Zhang, L.J.; Li, Z.C.; Zhou, Y.F.; Wang, Y.; Lu, J.H.; Li, J.X.; Qi, M.; Bolund, L.; Yashin, A.; Land, K.C.; Gregory, S.; Yang, Z.; Gottschalk, W.; Tao, W.; Wang, J.; Wang, J.; Xu, X.; Bae, H.; Nygaard, M.; Christiansen, L.; Christensen, K.; Franceschi, C.; Lutz, M.W.; Gu, J.; Tan, Q.H.; Perls, T.; Sebastiani, P.; Deelen, J.; Slagboom, E.; Hauser, E.; Xu, H.; Tian, X.L.; Yang, H.M. & Vaupel, J.W. (2016), Novel loci and pathways significantly associated with longevity, Scientific Reports 6.
- Djuardi, Y.; Supali, T.; Wibowo, H.; Heijmans, B.T.; Deelen, J.; Slagboom, E.P.; Houwing-Duistermaat, J.J.; Sartono, E. & Yazdanbakhsh, M. (2016), Maternal and child cytokine relationship in early life is not altered by cytokine gene polymorphisms, Genes and Immunity 17(7): 380-385.
- Dekkers, K.F.; Iterson, M. van; Slieker, R.C.; Moed, M.H.; Bonder, M.J.; Galen, M. van; Mei, H.L.; Zhernakova, D.V.; Berg, L.H. van den; Deelen, J.; Dongen, J. van; Heemst, D. van; Hofman, A.; Hottenga, J.J.; Kallen, C.J.H. van der; Schalkwijk, C.G.; Stehouwer, C.D.A.; Tigchelaar, E.F.; Uitterlinden, A.G.; Willemsen, G.; Zhernakova, A.; Franke, L.; Hoen, P.A.C. 't; Jansen, R.; Meurs, J. van; Boomsma, D.I.; Duijn, C.M. van; Greevenbroek, M.M.J. van; Veldink, J.H.; Wijmenga, C.; Zwet, E.W. van; Slagboom, P.E.; Jukema, J.W.; Heijmans, B.T. & BIOS Consortium (2016), Blood lipids influence DNA methylation in circulating cells, Genome Biology 17.
- Dekkers, K.F.; Slagboom, P.E.; Jukema, J.W. & Heijmans, B.T. (2016), The multifaceted interplay between lipids and epigenetics, Current Opinion in Lipidology 27(3): 288-294.
- Trompet, S.; Postmus, I.; Slagboom, P.E.; Heijmans, B.T.; Smit, R.A.J.; Maier, A.B.; Buckley, B.M.; Sattar, N.; Stott, D.J.; Ford, I.; Westendorp, R.G.J.; Craen, A.J.M. de & Jukema, J.W. (2016), Non-response to (statin) therapy: the importance of distinguishing non-responders from non-adherers in pharmacogenetic studies, European Journal of Clinical Pharmacology 72(4): 431-437.
- Dongen, J. van; Nivard, M.G.; Willemsen, G.; Hottenga, J.J.; Helmer, Q.; Dolan, C.V.; Ehli, E.A.; Davies, G.E.; Iterson, M. van; Breeze, C.E.; Beck, S.; Suchiman, H.E.; Jansen, R.; Meurs, J.B. van; Heijmans, B.T.; Slagboom, P.E.; Boomsma, D.I. & BIOS Consortium (2016), Genetic and environmental influences interact with age and sex in shaping the human methylome, Nature Communications 7.
- Ciccarone, F.; Malavolta, M.; Calabrese, R.; Guastafierro, T.; Bacalini, M.G.; Reale, A.; Franceschi, C.; Capri, M.; Hervonen, A.; Hurme, M.; Grubeck-Loebenstein, B.; Koller, B.; Bernhardt, U.; Schon, C.; Slagboom, E.; Toussaint, O.; Sikora, E.; Gonos, E.S.; Breusing, N.; Grune, T.; Jansen, E.; Dolle, M.; Moreno-Villanueva, M.; Sindlinger, T.; Burkle, A.; Zampieri, M. & Caiafa, P. (2016), Age-dependent expression of DNMT1 and DNMT3B in PBMCs from a large European population enrolled in the MARK-AGE study, Aging Cell 15(4): 755-765.
- Hehir-Kwa, J.Y.; Marschall, T.; Kloosterman, W.P.; Francioli, L.C.; Baaijens, J.A.; Dijkstra, L.J.; Abdellaoui, A.; Koval, V.; Thung, D.T.; Wardenaar, R.; Renkens, I.; Coe, B.P.; Deelen, P.; Ligt, J. de; Lameijer, E.W.; Dijk, F. van; Hormozdiari, F.; Uitterlinden, A.G.; Duijn, C.M. van; Eichler, E.E.; Bakker, P.I.W. de; Swertz, M.A.; Wijmenga, C.; Ommen, G.J.B. van; Slagboom, P.E.; Boomsma, D.I.; Schonhuth, A.; Ye, K.; Guryev, V. & Genome Netherlands Consortium (2016), A high-quality human reference panel reveals the complexity and distribution of genomic structural variants, Nature Communications 7.
- Vries, P.S. de; Chasman, D.I.; Sabater-Lleal, M.; Chen, M.H.; Huffman, J.E.; Steri, M.; Tang, W.H.; Teumer, A.; Marioni, R.E.; Grossmann, V.; Hottenga, J.J.; Trompet, S.; Muller-Nurasyid, M.; Zhao, J.H.; Brody, J.A.; Kleber, M.E.; Guo, X.Q.; Wang, J.J.; Auer, P.L.; Attia, J.R.; Yanek, L.R.; Ahluwalia, T.S.; Lahti, J.; Venturini, C.; Tanaka, T.; Bielak, L.F.; Joshi, P.K.; Rocanin-Arjo, A.; Kolcic, I.; Navarro, P.; Rose, L.M.; Oldmeadow, C.; Riess, H.; Mazur, J.; Basu, S.; Goel, A.; Yang, Q.; Ghanbari, M.; Willemsen, G.; Rumley, A.; Fiorillo, E.; Craen, A.J.M. de; Grotevendt, A.; Scott, R.; Taylor, K.D.; Delgado, G.E.; Yao, J.; Kifley, A.; Kooperberg, C.; Qayyum, R.; Lopez, L.M.; Berentzen, T.L.; Raikkonen, K.; Mangino, M.; Bandinelli, S.; Peyser, P.A.; Wild, S.; Tregouet, D.A.; Wright, A.F.; Marten, J.; Zemunik, T.; Morrison, A.C.; Sennblad, B.; Tofler, G.; Maat, M.P.M. de; Geus, E.J.C. de; Lowe, G.D.; Zoledziewska, M.; Sattar, N.; Binder, H.; Volker, U.; Waldenberger, M.; Khaw, K.T.; Mcknight, B.; Huang, J.; Jenny, N.S.; Holliday, E.G.; Qi, L.H.; Mcevoy, M.G.; Becker, D.M.; Starr, J.M.; Sarin, A.P.; Hysi, P.G.; Hernandez, D.G.; Jhun, M.A.; Campbell, H.; Hamsten, A.; Rivadeneira, F.; Mcardle, W.L.; Slagboom, P.E.; Zeller, T.; Koenig, W.; Psaty, B.M.; Haritunians, T.; Liu, J.M.; Palotie, A.; Uitterlinden, A.G.; Stott, D.J.; Hofman, A.; Franco, O.H.; Polasek, O.; Rudan, I.; Morange, P.E.; Wilson, J.F.; Kardia, S.L.R.; Ferrucci, L.; Spector, T.D.; Eriksson, J.G.; Hansen, T.; Deary, I.J.; Becker, L.C.; Scott, R.J.; Mitchell, P.; Marz, W.; Wareham, N.J.; Peters, A.; Greinacher, A.; Wild, P.S.; Jukema, J.W.; Boomsma, D.I.; Hayward, C.; Cucca, F.; Tracy, R.; Watkins, H.; Reiner, A.P.; Folsom, A.R.; Ridker, P.M.; O'Donnell, C.J.; Smith, N.L.; Strachan, D.P. & Dehghan, A. (2016), A meta-analysis of 120 246 individuals identifies 18 new loci for fibrinogen concentration, Human Molecular Genetics 25(2): 358-370.
- Valentini, E.; Zampieri, M.; Malavolta, M.; Bacalini, M.G.; Calabrese, R.; Guastafierro, T.; Reale, A.; Franceschi, C.; Hervonen, A.; Koller, B.; Bernhardt, J.; Slagboom, P.E.; Toussaint, O.; Sikora, E.; Gonos, E.S.; Breusing, N.; Grune, T.; Jansen, E.; Dolle, M.E.T.; Moreno-Villanueva, M.; Sindlinger, T.; Burkle, A.; Ciccarone, F. & Caiafa, P. (2016), Analysis of the machinery and intermediates of the 5hmC-mediated DNA demethylation pathway in aging on samples from the MARK-AGE Study, Aging 8(9): 1896-1922.
- Broekhuizen, K.; Gelder, J. de; Wijsman, C.A.; Wijsman, L.W.; Westendorp, R.G.J.; Verhagen, E.; Slagboom, P.E.; Craen, A.J. de; Mechelen, W. van; Heemst, D. van; Ouderaa, F. van der & Mooijaart, S.P. (2016), An Internet-Based Physical Activity Intervention to Improve Quality of Life of Inactive Older Adults: A Randomized Controlled Trial, JMIR 18(4).
- McCarthy, S.; , S. das; Kretzschmar, W.; Delaneau, O.; Wood, A.R.; Teumer, A.; Kang, H.M.; Fuchsberger, C.; Danecek, P.; Sharp, K.; Luo, Y.; Sidorel, C.; Kwong, A.; Timpson, N.; Koskinen, S.; Vrieze, S.; Scott, L.J.; Zhang, H.; Mahajan, A.; Veldink, J.; Peters, U.; Pato, C.; Duijn, C.M. van; Gillies, C.E.; Gandin, I.; Mezzavilla, M.; Gilly, A.; Cocca, M.; Traglia, M.; Angius, A.; Barrett, J.C.; Boomsma, D.; Branham, K.; Breen, G.; Brummett, C.M.; Busonero, F.; Campbell, H.; Chan, A.; Che, S.; Chew, E.; Collins, F.S.; Corbin, L.J.; Smith, G.D.; Dedoussis, G.; Dorr, M.; Farmaki, A.E.; Ferrucci, L.; Forer, L.; Fraser, R.M.; Gabriel, S.; Levy, S.; Groop, L.; Harrison, T.; Hattersley, A.; Holmen, O.L.; Hveem, K.; Kretzler, M.; Lee, J.C.; McGue, M.; Meitinger, T.; Melzer, D.; Min, J.L.; Mohlke, K.L.; Vincent, J.B.; Nauck, M.; Nickerson, D.; Palotie, A.; Pato, M.; Pirastu, N.; McInnis, M.; Richards, J.B.; Sala, C.; Salomaa, V.; Schlessinger, D.; Schoenherr, S.; Slagboom, P.E.; Small, K.; Spector, T.; Stambolian, D.; Tuke, M.; Tuomilehto, J.; Berg, L.H. van den; Rheenen, W. van; Volker, U.; Wijmenga, C.; Toniolo, D.; Zeggini, E.; Gasparini, P.; Sampson, M.G.; Wilson, J.F.; Frayling, T.; Bakker, P.I.W. de; Swertz, M.A.; McCarroll, S.; Kooperberg, C.; Dekker, A.; Altshuler, D.; Willer, C.; Iacono, W.; Ripatti, S.; Soranzo, N.; Walter, K.; Swaroop, A.; Cucca, F.; Anderson, C.A.; Myers, R.M.; Boehnke, M.; McCarthy, M.I.; Durbin, R.; Abecasis, G.; Marchini, J. & Haplotype Reference Consortium (2016), A reference panel of 64,976 haplotypes for genotype imputation, Nature Genetics 48(10): 1279-1283.
- Waaijer, M.E.C.; Westendorp, R.G.J.; Goldeck, D.; Gunn, D.A.; Pawelec, G.; Stijntjes, M.; Slagboom, P.E. & Maier, A.B. (2016), Assessment of health status by molecular measures in middle-aged to old persons, ready for clinical use?, Australasian Journal on Ageing 35: 70-71.
- Noordam, R.; Gunn, D.A.; Drielen, K. van; Westgate, G.; Slagboom, P.E.; Craen, A.J.M. de & Heemst, D. van (2016), Both low circulating insulin-like growth factor-1 and high-density lipoprotein cholesterol are associated with hair loss in middle-aged women, British Journal of Dermatology 175(4): 728-734.
- Stijntjes, M.; Craen, A.J.M. de; Grond, J. van der; Meskers, C.G.M.; Slagboom, P.E. & Maier, A.B. (2016), Cerebral Microbleeds and Lacunar Infarcts Are Associated with Walking Speed Independent of Cognitive Performance in Middle-Aged to Older Adults, Gerontology 62(5): 500-507.
- Rooden, S. van; Buijs, M.; Vliet, M.E. van; Versluis, M.J.; Webb, A.G.; Oleksik, A.M.; Wiel, L. van de; Middelkoop, H.A.M.; Blauw, G.J.; Weverling-Rynsburger, A.W.E.; Goos, J.D.C.; Flier, W.M. van der; Koene, T.; Scheltens, P.; Barkhof, F.; Rest, O. van de; Slagboom, P.E.; Buchem, M.A. van & Grond, J. van der (2016), Cortical phase changes measured using 7-T MRI in subjects with subjective cognitive impairment, and their association with cognitive function, NMR in Biomedicine 29(9): 1289-1294.
- Kroon, M.; Lameijer, E.W.; Lakenberg, N.; Hehir-Kwa, J.Y.; Thung, D.T.; Slagboom, P.E.; Kok, J.N. & Ye, K. (2016), Detecting dispersed duplications in high-throughput sequencing data using a database-free approach, Bioinformatics 32(4): 505-510.
- Waaijer, M.E.C.; Croco, E.; Westendorp, R.G.J.; Slagboom, P.E.; Sedivy, J.M.; Lorenzini, A. & Maier, A.B. (2016), DNA damage markers in dermal fibroblasts in vitro reflect chronological donor age, Aging 8(1): 147-157.
- Stijntjes, M.; Meskers, C.G.M.; Craen, A.J.M. de; Lummel, R.C. van; Rispens, S.M.; Slagboom, P.E. & Maier, A.B. (2016), Effect of calendar age on physical performance: A comparison of standard clinical measures with instrumented measures in middle-aged to older adults, Gait and Posture 45: 12-18.
- Spoel, E. van der; Roelfsema, F.; Jansen, S.W.; Akintola, A.A.; Ballieux, B.E.; Cobbaert, C.M.; Blauw, G.J.; Slagboom, P.E.; Westendorp, R.G.J.; Piji, H. & Heemst, D. van (2016), Familial longevity is not associated with Major Differences in the hypothalamic-Pituitary-gonadal axis in healthy Middle-aged Men, Frontiers in Endocrinology 7.
- Koopman, J.J.E.; Pijpe, J.; Bohringer, S.; Bodegom, D. van; Eriksson, U.K.; Sanchez-Faddeev, H.; Ziem, J.B.; Zwaan, B.; Slagboom, P.E.; Knijff, P. de & Westendorp, R.G.J. (2016), Genetic variants determining survival and fertility in an adverse African environment: a population-based large-scale candidate gene association study, Aging 8(7): 1364-1383.
- Kilpelainen, T.O.; Carli, J.F.M.; Skowronski, A.A.; Sun, Q.; Kriebel, J.; Feitosa, M.F.; Hedman, A.K.; Drong, A.W.; Hayes, J.E.; Zhao, J.H.; Pers, T.H.; Schick, U.; Grarup, N.; Kutalik, Z.; Trompet, S.; Mangino, M.; Kristiansson, K.; Beekman, M.; Lyytikainen, L.P.; Eriksson, J.; Henneman, P.; Lahti, J.; Tanaka, T.; Luan, J.A.; Greco, F. del; Pasko, D.; Renstrom, F.; Willems, S.M.; Mahajan, A.; Rose, L.M.; Guo, X.Q.; Liu, Y.M.; Kleber, M.E.; Perusse, L.; Gaunt, T.; Ahluwalia, T.S.; Sung, Y.J.; Ramos, Y.F.; Amin, N.; Amuzu, A.; Barroso, I.; Bellis, C.; Blangero, J.; Buckley, B.M.; Bohringer, S.; Chen, Y.D.I.; Craen, A.J.N. de; Crosslin, D.R.; Dale, C.E.; Dastani, Z.; Day, F.R.; Deelen, J.; Delgado, G.E.; Demirkan, A.; Finucane, F.M.; Ford, I.; Garcia, M.E.; Gieger, C.; Gustafsson, S.; Hallmans, G.; Hankinson, S.E.; Havulinna, A.S.; Herder, C.; Hernandez, D.; Hicks, A.A.; Hunter, D.J.; Illig, T.; Ingelsson, E.; Ioan-Facsinay, A.; Jansson, J.O.; Jenny, N.S.; Jorgensen, M.E.; Jorgensen, T.; Karlsson, M.; Koenig, W.; Kraft, P.; Kwekkeboom, J.; Laatikainen, T.; Ladwig, K.H.; LeDuc, C.A.; Lowe, G.; Lu, Y.C.; Marques-Vidal, P.; Meisinger, C.; Menni, C.; Morris, A.P.; Myers, R.H.; Mannisto, S.; Nalls, M.A.; Paternoster, L.; Peters, A.; Pradhan, A.D.; Rankinen, T.; Rasmussen-Torvik, L.J.; Rathmann, W.; Rice, T.K.; Richards, J.B.; Ridker, P.M.; Sattar, N.; Savage, D.B.; Soderberg, S.; Timpson, N.J.; Vandenput, L.; Heemst, D. van; Uh, H.W.; Vohl, M.C.; Walker, M.; Wichmann, H.E.; Widen, E.; Wood, A.R.; Yao, J.; Zeller, T.; Zhang, Y.Y.; Meulenbelt, I.; Kloppenburg, M.; Astrup, A.; Sorensen, T.I.A.; Sarzynski, M.A.; Rao, D.C.; Jousilahti, P.; Vartiainen, E.; Hofman, A.; Rivadeneira, F.; Uitterlinden, A.G.; Kajantie, E.; Osmond, C.; Palotie, A.; Eriksson, J.G.; Heliovaara, M.; Knekt, P.B.; Koskinen, S.; Jula, A.; Perola, M.; Huupponen, R.K.; Viikari, J.S.; Kahonen, M.; Lehtimaki, T.; Raitakari, O.T.; Mellstrom, D.; Lorentzon, M.; Casas, J.P.; Bandinelli, S.; Marz, W.; Isaacs, A.; Dijk, K.W. van; Duijn, C.M. van; Harris, T.B.; Bouchard, C.; Allison, M.A.; Chasman, D.I.; Ohlsson, C.; Lind, L.; Scott, R.A.; Langenberg, C.; Wareham, N.J.; Ferrucci, L.; Frayling, T.M.; Pramstaller, P.P.; Borecki, I.B.; Waterworth, D.M.; Bergmann, S.; Waeber, G.; Vollenweider, P.; Vestergaard, H.; Hansen, T.; Pedersen, O.; Hu, F.B.; Slagboom, P.E.; Grallert, H.; Spector, T.D.; Jukema, J.W.; Klein, R.J.; Schadt, E.E.; Franks, P.W.; Lindgren, C.M.; Leibel, R.L. & Loos, R.J.F. (2016), Genome-wide meta-analysis uncovers novel loci influencing circulating leptin levels, Nature Communications 7.
- Hillger, J.M.; Diehl, C.; Spronsen, E. van; Boomsma, D.I.; Slagboom, P.E.; Heitman, L.H. & Ijzerman, A.P. (2016), Getting personal: Endogenous adenosine receptor signaling in lymphoblastoid cell lines, Biochemical Pharmacology 115: 114-122.
- Ibrahim-Verbaas, C.A.; Bressler, J.; Debette, S.; Schuur, M.; Smith, A.V.; Bis, J.C.; Davies, G.; Trompet, S.; Smith, J.A.; Wolf, C.; Chibnik, L.B.; Liu, Y.; Vitart, V.; Kirin, M.; Petrovic, K.; Polasek, O.; Zgaga, L.; Fawns-Ritchie, C.; Hoffmann, P.; Karjalainen, J.; Lahti, J.; Llewellyn, D.J.; Schmidt, C.O.; Mather, K.A.; Chouraki, V.; Sun, Q.; Resnick, S.M.; Rose, L.M.; Oldmeadow, C.; Stewart, M.; Smith, B.H.; Gudnason, V.; Yang, Q.; Mirza, S.S.; Jukema, J.W.; Dejager, P.L.; Harris, T.B.; Liewald, D.C.; Amin, N.; Coker, L.H.; Stegle, O.; Lopez, O.L.; Schmidt, R.; Teumer, A.; Ford, I.; Karbalai, N.; Becker, J.T.; Jonsdottir, M.K.; Au, R.; Fehrmann, R.S.N.; Herms, S.; Nalls, M.; Zhao, W.; Turner, S.T.; Yaffe, K.; Lohman, K.; Swieten, J.C. van; Kardia, S.L.R.; Knopman, D.S.; Meeks, W.M.; Heiss, G.; Holliday, E.G.; Schofield, P.W.; Tanaka, T.; Stott, D.J.; Wang, J.; Ridker, P.; Gow, A.J.; Pattie, A.; Starr, J.M.; Hocking, L.J.; Armstrong, N.J.; McLachlan, S.; Shulman, J.M.; Pilling, L.C.; Eiriksdottir, G.; Scott, R.J.; Kochan, N.A.; Palotie, A.; Hsieh, Y.C.; Eriksson, J.G.; Penman, A.; Gottesman, R.F.; Oostra, B.A.; Yu, L.; DeStefano, A.L.; Beiser, A.; Garcia, M.; Rotter, J.I.; Nothen, M.M.; Hofman, A.; Slagboom, P.E.; Westendorp, R.G.J.; Buckley, B.M.; Wolf, P.A.; Uitterlinden, A.G.; Psaty, B.M.; Grabe, H.J.; Bandinelli, S.; Chasman, D.I.; Grodstein, F.; Roikkonen, K.; Lambert, J.C.; Porteous, D.J.; Price, J.F.; Sachdev, P.S.; Ferrucci, L.; Attia, J.R.; Rudan, I.; Hayward, C.; Wright, A.F.; Wilson, J.F.; Cichon, S.; Franke, L.; Schmidt, H.; Ding, J.; Craen, A.J.M. de; Fornage, M.; Bennett, D.A.; Deary, I.J.; Ikram, M.A.; Launer, L.J.; Fitzpatrick, A.L.; Seshadri, S.; Duijn, C.M. van; Mosley, T.H. & Generation Scotland (2016), GWAS for executive function and processing speed suggests involvement of the CADM2 gene, Molecular Psychiatry 21(2): 189-197.
- Sala, M.; Grond, J. van der; Mutsert, R. de; Heemst, D. van; Slagboom, E.; Kroft, L.J.M. & Roos, A. de (2016), Liver Fat Assessed With CT Relates to MRI Markers of Incipient Brain Injury in Middle-Aged to Elderly Overweight Persons, American Journal of Roentgenology 206(5): 1087-1092.
- Waaijer, M.E.C.; Gunn, D.A.; Adams, P.D.; Pawlikowski, J.S.; Griffiths, C.E.M.; Heemst, D. van; Slagboom, P.E.; Westendorp, R.G.J. & Maier, A.B. (2016), P16INK4a Positive Cells in Human Skin Are Indicative of Local Elastic Fiber Morphology, Facial Wrinkling, and Perceived Age, Journals of Gerontology, Series A 71(8): 1022-1028.
- Li, M.K.; Rothwell, R.; Vermaat, M.; Wachsmuth, M.; Schroder, R.; Laros, J.F.J.; Oven, M. van; Bakker, P.I.W. de; Bovenberg, J.A.; Duijn, C.M. van; Ommen, G.J.B. van; Slagboom, P.E.; Swertz, M.A.; Wijmenga, C.; Kayser, M.; Boomsma, D.I.; Zollner, S.; Knijff, P. de; Stoneking, M. & Genome Netherlands Consortium (2016), Transmission of human mtDNA heteroplasmy in the Genome of the Netherlands families: support for a variable-size bottleneck, Genome Research 26(4): 417-426.
- Beekman, M.; Uh, H.W.; Heemst, D. van; Wuhrer, M.; Ruhaak, L.R.; Gonzalez-Covarrubias, V.; Hankemeier, T.; Houwing-Duistermaat, J.J. & Slagboom, P.E. (2016), Classification for Longevity Potential: The Use of Novel Biomarkers, Frontiers in Public Health 4.
- Castano-Betancourt, M.C.; Evans, D.S.; Ramos, Y.F.M.; Boer, C.G.; Metrustry, S.; Liu, Y.F.; Hollander, W. den; Rooij, J. van; Kraus, V.B.; Yau, M.S.; Mitchell, B.D.; Muir, K.; Hofman, A.; Doherty, M.; Doherty, S.; Zhang, W.Y.; Kraaij, R.; Rivadeneira, F.; Barrett-Connor, E.; Maciewicz, R.A.; Arden, N.; Nelissen, R.G.H.H.; Kloppenburg, M.; Jordan, J.M.; Nevitt, M.C.; Slagboom, E.P.; Hart, D.J.; Lafeber, F.; Styrkarsdottir, U.; Zeggini, E.; Evangelou, E.; Spector, T.D.; Uitterlinden, A.G.; Lane, N.E.; Meulenbelt, I.; Valdes, A.M. & Meurs, J.B.J. van (2016), Novel Genetic Variants for Cartilage Thickness and Hip Osteoarthritis, PLoS Genetics 12(10).
- Bomer, N.; Hollander, W. den; Suchiman, H.; Houtman, E.; Slieker, R.C.; Heijmans, B.T.; Slagboom, P.E.; Nelissen, R.G.H.H.; Ramos, Y.F.M. & Meulenbelt, I. (2016), Neo-cartilage engineered from primary chondrocytes is epigenetically similar to autologous cartilage, in contrast to using mesenchymal stem cells, Osteoarthritis and Cartilage 24(8): 1423-1430.
- Spoel, E. van der; Jansen, S.W.; Akintola, A.A.; Ballieux, B.E.; Cobbaert, C.M.; Slagboom, P.E.; Blauw, G.J.; Westendorp, R.G.J.; Pijl, H.; Roelfsema, F. & Heemst, D. van (2016), Growth hormone secretion is diminished and tightly controlled in humans enriched for familial longevity, Aging Cell 15(6): 1126-1131.
- Postmus, I.; Warren, H.R.; Trompet, S.; Arsenault, B.J.; Avery, C.L.; Bis, J.C.; Chasman, D.I.; Keyser, C.E. de; Deshmukh, H.A.; Evans, D.S.; Feng, Q.P.; Li, X.H.; Smit, R.A.J.; Smith, A.V.; Sun, F.G.; Taylor, K.D.; Arnold, A.M.; Barnes, M.R.; Barratt, B.J.; Betteridge, J.; Boekholdt, S.M.; Boerwinkle, E.; Buckley, B.M.; Chen, Y.D.I.; Craen, A.J.M. de; Cummings, S.R.; Denny, J.C.; Dube, M.P.; Durrington, P.N.; Eiriksdottir, G.; Ford, I.; Guo, X.Q.; Harris, T.B.; Heckbert, S.R.; Hofman, A.; Hovingh, G.K.; Kastelein, J.J.P.; Launer, L.J.; Liu, C.T.; Liu, Y.M.; Lumley, T.; McKeigue, P.M.; Munroe, P.B.; Neil, A.; Nickerson, D.A.; Nyberg, F.; O'Brien, E.; O'Donnell, C.J.; Post, W.; Poulter, N.; Vasan, R.S.; Rice, K.; Rich, S.S.; Rivadeneira, F.; Sattar, N.; Sever, P.; Shaw-Hawkins, S.; Shields, D.C.; Slagboom, P.E.; Smith, N.L.; Smith, J.D.; Sotoodehnia, N.; Stanton, A.; Stott, D.J.; Stricker, B.H.; Sturmer, T.; Uitterlinden, A.G.; Wei, W.Q.; Westendorp, R.G.J.; Whitsel, E.A.; Wiggins, K.L.; Wilke, R.A.; Ballantyne, C.M.; Colhoun, H.M.; Cupples, L.A.; Franco, O.H.; Gudnason, V.; Hitman, G.; Palmer, C.N.A.; Psaty, B.M.; Ridker, P.M.; Stafford, J.M.; Stein, C.M.; Tardif, J.C.; Caulfield, M.J.; Jukema, J.W.; Rotter, J.I. & Krauss, R.M. (2016), Meta-analysis of genome-wide association studies of HDL cholesterol response to statins, Journal of Medical Genetics 53(12): 835-+.
- Akker, E.B. van den; Pitts, S.J.; Deelen, J.; Moed, M.H.; Potluri, S.; Rooij, J. van; Suchiman, H.E.D.; Lakenberg, N.; Dijcker, W.J. de; Uitterlinden, A.G.; Kraaij, R.; Hofman, A.; Craen, A.J.M. de; Houwing-Duistermaat, J.J.; Ommen, G.J.B. van; Cox, D.R.; Meurs, J.B.J. van; Beekman, M.; Reinders, M.J.T.; Slagboom, P.E. & Genome Netherlands Consortium (2016), Uncompromised 10-year survival of oldest old carrying somatic mutations in DNMT3A and TET2, Blood 127(11): 1512-1515.
- Schutte, B.A.M.; Akker, E.B. van den; Deelen, J.; Rest, O. van de; Heemst, D. van; Feskens, E.J.M.; Beekman, M. & Slagboom, P.E. (2016), The effect of standardized food intake on the association between BMI and H-1-NMR metabolites, Scientific Reports 6.
- Ye, K.; Wang, J.Y.; Jayasinghe, R.; Lameijer, E.W.; McMichael, J.F.; Ning, J.; McLellan, M.D.; Xie, M.C.; Cao, S.; Yellapantula, V.; Huang, K.L.; Scott, A.; Foltz, S.; Niu, B.F.; Johnson, K.J.; Moed, M.; Slagboom, P.E.; Chen, F.; Wendl, M.C. & Ding, L. (2016), Systematic discovery of complex insertions and deletions in human cancers, Nature Medicine 22(1): 97-+.
- Rest, O. van de; Schutte, B.A.M.; Deelen, J.; Stassen, S.A.M.; Akker, E.B. van den; Heemst, D. van; Dibbets-Schneider, P.; Dipten-Van Der Veen, R.A. van; Kelderman, M.; Hankemeier, T.; Mooijaart, S.P.; Grond, J. van der; Houwing-Duistermaat, J.J.; Beekman, M.; Feskens, E.J.M. & Slagboom, P.E. (2016), Metabolic effects of a 13-weeks lifestyle intervention in older adults: The Growing Old Together Study, Aging 8(1): 111-126.
- Deelen, J.; Akker, E.B. van den; Trompet, S.; Heemst, D. van; Mooijaart, S.P.; Slagboom, P.E. & Beekman, M. (2016), Employing biomarkers of healthy ageing for leveraging genetic studies into human longevity, Experimental Gerontology 82: 166-174.
- Slieker, R.C.; Iterson, M. van; Luijk, R.; Beekman, M.; Zhernakova, D.V.; Moed, M.H.; Mei, H.L.; Galen, M. van; Deelen, P.; Bonder, M.J.; Zhernakova, A.; Uitterlinden, A.G.; Tigchelaar, E.F.; Stehouwer, C.D.A.; Schalkwijk, C.G.; Kallen, C.J.H. van der; Hofman, A.; Heemst, D. van; Geus, E.J. de; Dongen, J. van; Deelen, J.; Berg, L.H. van den; Meurs, J. van; Jansen, R.; Hoen, P.A.C. 't; Franke, L.; Wijmenga, C.; Veldink, J.H.; Swertz, M.A.; Greevenbroek, M.M.J. van; Duijn, C.M. van; Boomsma, D.I.; Slagboom, P.E.; Heijmans, B.T. & BIOS Consortium (2016), Age-related accrual of methylomic variability is linked to fundamental ageing mechanisms, Genome Biology 17.
- Noordam, R.; Oudt, C.H.; Deelen, J.; Slagboom, P.E.; Beekman, M. & Heemst, D. van (2016), Assessment of the contribution of APOE gene variants to metabolic phenotypes associated with familial longevity at middle age, Aging 8(8): 1790-1801.
- Liu, F.; Hamer, M.A.; Deelen, J.; Lall, J.S.; Jacobs, L.; Heemst, D. van; Murray, P.G.; Wollstein, A.; Craen, A.J.M. de; Uh, H.W.; Zeng, C.Q.; Hofman, A.; Uitterlinden, A.G.; Houwing-Duistermaat, J.J.; Pardo, L.M.; Beekman, M.; Slagboom, P.E.; Nijsten, T.; Kayser, M. & Gunn, D.A. (2016), The MC1R Gene and Youthful Looks, Current Biology 26(9): 1213-1220.
- Teumer, A.; Qi, Q.B.; Nethander, M.; Aschard, H.; Bandinelli, S.; Beekman, M.; Berndt, S.I.; Bidlingmaier, M.; Broer, L.; Cappola, A.; Ceda, G.P.; Chanock, S.; Chen, M.H.; Chen, T.C.; Chen, Y.D.I.; Chung, J.; Miglianico, F.D.; Eriksson, J.; Ferrucci, L.; Friedrich, N.; Gnewuch, C.; Goodarzi, M.O.; Grarup, N.; Guo, T.W.; Hammer, E.; Hayes, R.B.; Hicks, A.A.; Hofman, A.; Houwing-Duistermaat, J.J.; Hu, F.; Hunter, D.J.; Husemoen, L.L.; Isaacs, A.; Jacobs, K.B.; Janssen, J.A.M.J.L.; Jansson, J.O.; Jehmlich, N.; Johnson, S.; Juul, A.; Karlsson, M.; Kilpelainen, T.O.; Kovacs, P.; Kraft, P.; Li, C.; Linneberg, A.; Liu, Y.M.; Loos, R.J.F.; Lorentzon, M.; Lu, Y.C.; Maggio, M.; Magi, R.; Meigs, J.; Mellstrom, D.; Nauck, M.; Newman, A.B.; Pollak, M.N.; Pramstaller, P.P.; Prokopenko, I.; Psaty, B.M.; Reincke, M.; Rimm, E.B.; Rotter, J.I.; Saint Pierre, A.; Schurmann, C.; Seshadri, S.; Sjogren, K.; Slagboom, P.E.; Strickler, H.D.; Stumvoll, M.; Suh, Y.S.; Sun, Q.; Zhang, C.L.; Svensson, J.; Tanaka, T.; Tare, A.; Tonjes, A.; Uh, H.W.; Duijn, C.M. van; Heemst, D. van; Vandenput, L.; Vasan, R.S.; Volker, U.; Willems, S.M.; Ohlsson, C.; Wallaschofski, H.; Kaplan, R.C.; CHARGE Longevity Working Grp & Body Composition Genetics Consorti (2016), Genomewide meta-analysis identifies loci associated with IGF-I and IGFBP-3 levels with impact on age-related traits, Aging Cell 15(5): 811-824.
- Nygaard, M.; Debrabant, B.; Tan, Q.H.; Deelen, J.; Andersen-Ranberg, K.; Craen, A.J.M. de; Beekman, M.; Jeune, B.; Slagboom, P.E.; Christensen, K. & Christiansen, L. (2016), Copy number variation associates with mortality in long-lived individuals: a genome-wide assessment, Aging Cell 15(1): 49-55.
- Kroef, S. van der; Noordam, R.; Deelen, J.; Akintola, A.A.; Jansen, S.W.M.; Postmus, I.; Wijsman, C.A.; Beekman, M.; Mooijaart, S.P.; Slagboom, P.E. & Heemst, D. van (2016), Association between the rs7903146 Polymorphism in the TCF7L2 Gene and Parameters Derived with Continuous Glucose Monitoring in Individuals without Diabetes, PLoS ONE 11(2).
- Kettunen, J.; Demirkan, A.; Wurtz, P.; Draisma, H.H.M.; Haller, T.; Rawal, R.; Vaarhorst, A.; Kangas, A.J.; Lyytikainen, L.P.; Pirinen, M.; Pool, R.; Sarin, A.P.; Soininen, P.; Tukiainen, T.; Wang, Q.; Tiainen, M.; Tynkkynen, T.; Amin, N.; Zeller, T.; Beekman, M.; Deelen, J.; Dijk, K.W. van; Esko, T.; Hottenga, J.J.; Leeuwen, E.M. van; Lehtimaki, T.; Mihailov, E.; Rose, R.J.; Craen, A.J.M. de; Gieger, C.; Kahonen, M.; Perola, M.; Blankenberg, S.; Savolainen, M.J.; Verhoeven, A.; Viikari, J.; Willemsen, G.; Boomsma, D.I.; Duijn, C.M. van; Eriksson, J.; Jula, A.; Jarvelin, M.R.; Kaprio, J.; Metspalu, A.; Raitakari, O.; Salomaa, V.; Slagboom, P.E.; Waldenberger, M.; Ripatti, S. & Ala-Korpela, M. (2016), Genome-wide study for circulating metabolites identifies 62 loci and reveals novel systemic effects of LPA, Nature Communications 7.
- Bomer, N.; Cornelis, F.M.F.; Ramos, Y.F.M.; Hollander, W. den; Storms, L.; Breggen, R. van der; Lakenberg, N.; Slagboom, P.E.; Meulenbelt, I. & Lories, R.J.L. (2016), The effect of forced exercise on knee joints in Dio2(-/-) mice: type II iodothyronine deiodinase-deficient mice are less prone to develop OA-like cartilage damage upon excessive mechanical stress, Annals of the Rheumatic Diseases 75(3): 571-577.
- Leeuwen, E.M. van; Sabo, A.; Bis, J.C.; Huffman, J.E.; Manichaikul, A.; Smith, A.V.; Feitosa, M.F.; Demissie, S.; Joshi, P.K.; Duan, Q.; Marten, J.; Klinken, J.B. van; Surakka, I.; Nolte, I.M.; Zhang, W.H.; Mbarek, H.; Li-Gao, R.F.; Trompet, S.; Verweij, N.; Evangelou, E.; Lyytikainen, L.P.; Tayo, B.O.; Deelen, J.; Most, P.J. van der; Laan, S.W. van der; Arking, D.E.; Morrison, A.; Dehghan, A.; Franco, O.H.; Hofman, A.; Rivadeneira, F.; Sijbrands, E.J.; Uitterlinden, A.G.; Mychaleckyj, J.C.; Campbell, A.; Hocking, L.J.; Padmanabhan, S.; Brody, J.A.; Rice, K.M.; White, C.C.; Harris, T.; Isaacs, A.; Campbell, H.; Lange, L.A.; Rudan, I.; Kolcic, I.; Navarro, P.; Zemunik, T.; Salomaa, V.; Kooner, A.S.; Kooner, J.S.; Lehne, B.; Scott, W.R.; Tan, S.T.; Geus, E.J. de; Milaneschi, Y.; Penninx, B.W.J.H.; Willemsen, G.; Mutsert, R. de; Ford, I.; Gansevoort, R.T.; Segura-Lepe, M.P.; Raitakari, O.T.; Viikari, J.S.; Nikus, K.; Forrester, T.; McKenzie, C.A.; Craen, A.J.M. de; Ruijter, H.M. de; Pasterkamp, G.; Snieder, H.; Oldehinkel, A.J.; Slagboom, P.E.; Cooper, R.S.; Kahonen, M.; Lehtimaki, T.; Elliott, P.; Harst, P. van der; Jukema, J.W.; Mook-Kanamori, D.O.; Boomsma, D.I.; Chambers, J.C.; Swertz, M.; Ripatti, S.; Dijk, K.W. van; Vitart, V.; Polasek, O.; Hayward, C.; Wilson, J.G.; Wilson, J.F.; Gudnason, V.; Rich, S.S.; Psaty, B.M.; Borecki, I.B.; Boerwinkle, E.; Rotter, J.I.; Cupples, L.A.; Duijn, C.M. van & CHARGE Lipids Working Grp (2016), Meta-analysis of 49 549 individuals imputed with the 1000 Genomes Project reveals an exonic damaging variant in ANGPTL4 determining fasting TG levels, Journal of Medical Genetics 53(7): 441-449.
- Cornelis, F.M.; Peeters, T.; Guns, L.A.K.; Storms, L.; Hollander, W. den; Meulenbelt, I. & Lories, R.J. (2016), LOSS OF ANP32A IS ASSOCIATED WITH INCREASED CARTILAGE DAMAGE IN OSTEOARTHRITIS THROUGH AN ATM-ROS DEPENDENT MECHANISM, Osteoarthritis and Cartilage 24: S384-S384.
- (2016), The effect of standardized food intake on the association between BMI and 1H-NMR metabolites., Scientific Reports.
- Suchiman, H.E.D.; Slieker, R.C.; Kremer, D.; Slagboom, P.E.; Heijmans, B.T. & Tobi, E.W. (2015), Design, measurement and processing of region-specific DNA methylation assays: the mass spectrometry-based method EpiTYPER, Frontiers in Genetics 6.
- Slieker, R.C.; Roost, M.S.; Iperen, L. van; Suchiman, H.E.D.; Tobi, E.W.; Carlotti, F.; Koning, E.J.P. de; Slagboom, P.E.; Heijmans, B.T. & Lopes, S.M.C.D. (2015), DNA Methylation Landscapes of Human Fetal Development, PLoS Genetics 11(10).
- Reinards, T.H.C.M.; Albers, H.M.; Brinkman, D.M.C.; Kamphuis, S.S.M.; Rossum, M.A.J. van; Girschick, H.J.; Wouters, C.; Hoppenreijs, E.P.A.H.; Saurenmann, R.K.; Hinks, A.; Ellis, J.A.; Bakker, E.; Verduijn, W.; Slagboom, P.; Huizinga, T.W.J.; Toes, R.E.M.; Houwing-Duistermaat, J.J.; Cate, R. ten & Schilham, M.W. (2015), CD226 (DNAM-1) is associated with susceptibility to juvenile idiopathic arthritis, Annals of the Rheumatic Diseases 74(12): 2193-2198.
- Ramos, Y.F.M.; Bos, S.D.; Breggen, R. van der; Kloppenburg, M.; Ye, K.; Lameijer, E.W.E.M.W.; Nelissen, R.G.H.H.; Slagboom, P.E. & Meulenbelt, I. (2015), A gain of function mutation in TNFRSF11B encoding osteoprotegerin causes osteoarthritis with chondrocalcinosis, Annals of the Rheumatic Diseases 74(9): 1756-1762.
- Hofer, E.; Cavalieri, M.; Bis, J.C.; DeCarli, C.; Fornage, M.; Sigurdsson, S.; Srikanth, V.; Trompet, S.; Verhaaren, B.F.J.; Wolf, C.; Yang, Q.; Adams, H.H.H.; Amouyel, P.; Beiser, A.; Buckley, B.M.; Callisaya, M.; Chauhan, G.; Craen, A.J.M. de; Dufouil, C.; Duijn, C.M. van; Ford, I.; Freudenberger, P.; Gottesman, R.F.; Gudnason, V.; Heiss, G.; Hofman, A.; Lumley, T.; Martinez, O.; Mazoyer, B.; Moran, C.; Niessen, W.J.; Phan, T.; Psaty, B.M.; Satizabal, C.L.; Sattar, N.; Schilling, S.; Shibata, D.K.; Slagboom, P.E.; Smith, A.; Stott, D.J.; Taylor, K.D.; Thomson, R.; Toglhofer, A.M.; Tzourio, C.; Buchem, M. van; Wang, J.; Westendorp, R.G.J.; Windham, B.G.; Vernooij, M.W.; Zijdenbos, A.; Beare, R.; Debette, S.; Ikram, M.A.; Jukema, J.W.; Launer, L.J.; Longstreth, W.T.; Mosley, T.H.; Seshadri, S.; Schmidt, H.; Schmidt, R. & Cohorts Heart Aging Res Genomic Ep (2015), White Matter Lesion Progression Genome-Wide Search for Genetic Influences, Stroke 46(11): 3048-3057.
- Bis, J.C.; Sitlani, C.; Irvin, R.; Avery, C.L.; Smith, A.V.; Sun, F.G.; Evans, D.S.; Musani, S.K.; Li, X.H.; Trompet, S.; Krijthe, B.P.; Harris, T.B.; Quibrera, P.M.; Brody, J.A.; Demissie, S.; Davis, B.R.; Wiggins, K.L.; Tranah, G.J.; Lange, L.A.; Sotoodehnia, N.; Stott, D.J.; Franco, O.H.; Launer, L.J.; Sturmer, T.; Taylor, K.D.; Cupples, L.A.; Eckfeldt, J.H.; Smith, N.L.; Liu, Y.M.; Wilson, J.G.; Heckbert, S.R.; Buckley, B.M.; Ikram, M.A.; Boerwinkle, E.; Chen, Y.D.I.; Craen, A.J.M. de; Uitterlinden, A.G.; Rotter, J.I.; Ford, I.; Hofman, A.; Sattar, N.; Slagboom, P.E.; Westendorp, R.G.J.; Gudnason, V.; Vasan, R.S.; Lumley, T.; Cummings, S.R.; Taylor, H.A.; Post, W.; Jukema, J.W.; Stricker, B.H.; Whitsel, E.A.; Psaty, B.M. & Arnett, D. (2015), Drug-Gene Interactions of Antihypertensive Medications and Risk of Incident Cardiovascular Disease: A Pharmacogenomics Study from the CHARGE Consortium, PLoS ONE 10(10).
- Altmann-Schneider, I.; Craen, A.J.M. de; Berg-Huysmans, A.A. van den; Slagboom, P.; Westendorp, R.G.J.; Buchem, M.A. van & Grond, J. van der (2015), An In Vivo Study on Brain Microstructure in Biological and Chronological Ageing, PLoS ONE 10(3).
- Akintola, A.A.; Berg, A. van den; Buchem, M.A. van; Jansen, S.W.; Slagboom, E.P.; Westendorp, R.G.; Grond, J. van der & Heemst, D. van (2015), Associations between insulin action and integrity of brain microstructure differ with familial longevity and with age, Frontiers in Aging Neuroscience 7.
- Sala, M.L.; Roll, B.; Bijl, N. van der; Grond, J. van der; Craen, A.J.M. de; Slagboom, E.P.; Geest, R. van der; Roos, A. de & Kroft, L.J.M. (2015), Genetically determined prospect to become long-lived is associated with less abdominal fat and in particular less abdominal visceral fat in men, Age and Ageing 44(4): 713-717.
- Jansen, S.W.; Akintola, A.A.; Roelfsema, F.; Spoel, E. van der; Cobbaert, C.M.; Ballieux, B.E.; Egri, P.; Kvarta-Papp, Z.; Gereben, B.; Fekete, C.; Slagboom, P.E.; Grond, J. van der; Demeneix, B.A.; Pijl, H.; Westendorp, R.G.J. & Heemst, D. van (2015), Human longevity is characterised by high thyroid stimulating hormone secretion without altered energy metabolism.
- Gunn, D.A.; Dick, J.L.; Heemst, D. van; Griffiths, C.E.M.; Tomlin, C.C.; Murray, P.G.; Griffiths, T.W.; Ogden, S.; Mayes, A.E.; Westendorp, R.G.J.; Slagboom, P.E. & Craen, A.J.M. de (2015), Lifestyle and youthful looks, British Journal of Dermatology 172(5): 1338-1345.
- Verhaaren, B.F.J.; Debette, S.; Bis, J.C.; Smith, J.A.; Ikram, M.K.; Adams, H.H.; Beecham, A.H.; Rajan, K.B.; Lopez, L.M.; Barral, S.; Buchem, M.A. van; Grond, J. van der; Smith, A.V.; Hegenscheid, K.; Aggarwal, N.T.; Andrade, M. de; Atkinson, E.J.; Beekman, M.; Beiser, A.S.; Blanton, S.H.; Boerwinkle, E.; Brickman, A.M.; Bryan, R.N.; Chauhan, G.; Chen, C.P.L.H.; Chouraki, V.; Craen, A.J.M. de; Crivello, F.; Deary, I.J.; Deelen, J.; Jager, P.L. de; Dufouil, C.; Elkind, M.S.V.; Evans, D.A.; Freudenberger, P.; Gottesman, R.F.; Gudnason, V.; Habes, M.; Heckbert, S.R.; Heiss, G.; Hilal, S.; Hofer, E.; Hofman, A.; Ibrahim-Verbaas, C.A.; Knopman, D.S.; Lewis, C.E.; Liao, J.M.; Liewald, D.C.M.; Luciano, M.; Lugt, A. van der; Martinez, O.O.; Mayeux, R.; Mazoyer, B.; Nalls, M.; Nauck, M.; Niessen, W.J.; Oostra, B.A.; Psaty, B.M.; Rice, K.M.; Rotter, J.I.; Sarnowski, B. von; Schmidt, H.; Schreiner, P.J.; Schuur, M.; Sidney, S.S.; Sigurdsson, S.; Slagboom, P.E.; Stott, D.J.M.; Swieten, J.C. van; Teumer, A.; Toglhofer, A.M.; Traylor, M.; Trompet, S.; Turner, S.T.; Tzourio, C.; Uh, H.W.; Uitterlinden, A.G.; Vernooij, M.W.; Wang, J.J.; Wong, T.Y.; Wardlaw, J.M.; Windham, B.G.; Wittfeld, K.; Wolf, C.; Wright, C.B.; Yang, Q.; Zhao, W.; Zijdenbos, A.; Jukema, J.W.; Sacco, R.L.; Kardia, S.L.R.; Amouyel, P.; Mosley, T.H.; Longstreth, W.T.; DeCarli, C.C.; Duijn, C.M. van; Schmidt, R.; Launer, L.J.; Grabe, H.J.; Seshadri, S.S.; Ikram, M.A. & Fornage, M. (2015), Multiethnic Genome-Wide Association Study of Cerebral White Matter Hyperintensities on MRI, Circulation: Cardiovascular Genetics 8(2): 398-+.
- Akintola, A.A.; Berg, A. van den; Altmann-Schneider, I.; Jansen, S.W.; Buchem, M.A. van; Slagboom, P.E.; Westendorp, R.G.; Heemst, D. van & Grond, J. van der (2015), Parameters of glucose metabolism and the aging brain: a magnetization transfer imaging study of brain macro- and micro-structure in older adults without diabetes, AGE 37(4).
- Germain, M.; Chasman, D.I.; Haan, H. de; Tang, W.; Lindstrom, S.; Weng, L.C.; Andrade, M. de; Visser, M.C.H. de; Wiggins, K.L.; Suchon, P.; Saut, N.; Smadja, D.M.; Gal, G. le; Vlieg, A.V.; Narzo, A. di; Hao, K.; Nelson, C.P.; Rocanin-Arjo, A.; Folkersen, L.; Monajemi, R.; Rose, L.M.; Brody, J.A.; Slagboom, E.; Aissi, D.; Gagnon, F.; Deleuze, J.F.; Deloukas, P.; Tzourio, C.; Dartigues, J.F.; Berr, C.; Taylor, K.D.; Civelek, M.; Eriksson, P.; Psaty, B.M.; Houwing-Duitermaat, J.; Goodall, A.H.; Cambien, F.; Kraft, P.; Amouyel, P.; Samani, N.J.; Basu, S.; Ridker, P.M.; Rosendaal, F.R.; Kabrhel, C.; Folsom, A.R.; Heit, J.; Reitsma, P.H.; Tregouet, D.A.; Smith, N.L.; Morange, P.E. & Cardiogenics Consortium (2015), Meta-analysis of 65,734 Individuals Identifies TSPAN15 and SLC44A2 as Two Susceptibility Loci for Venous Thromboembolism, American Journal of Human Genetics 96(4): 532-542.
- Widya, R.L.; Kroft, L.J.M.; Altmann-Schneider, I.; Berg-Huysmans, A.A. van den; Bijl, N. van der; Roos, A. de; Lamb, H.J.; Buchem, M.A. van; Slagboom, P.E.; Heemst, D. van; Grond, J. van der & Leiden Longevity Study Grp (2015), Visceral Adipose Tissue is Associated with Microstructural Brain Tissue Damage, Obesity 23(5): 1092-1096.
- Surakka, I.; Horikoshi, M.; Magi, R.; Sarin, A.P.; Mahajan, A.; Lagou, V.; Marullo, L.; Ferreira, T.; Miraglio, B.; Timonen, S.; Kettunen, J.; Pirinen, M.; Karjalainen, J.; Thorleifsson, G.; Hagg, S.; Hottenga, J.J.; Isaacs, A.; Ladenvall, C.; Beekman, M.; Esko, T.; Ried, J.S.; Nelson, C.P.; Willenborg, C.; Gustafsson, S.; Westra, H.J.; Blades, M.; Craen, A.J.M. de; Geus, E.J. de; Deelen, J.; Grallert, H.; Hamsten, A.; Havulinna, A.S.; Hengstenberg, C.; Houwing-Duistermaat, J.J.; Hypponen, E.; Karssen, L.C.; Lehtimaki, T.; Lyssenko, V.; Magnusson, P.K.E.; Mihailov, E.; Muller-Nurasyid, M.; Mpindi, J.P.; Pedersen, N.L.; Penninx, B.W.J.H.; Perola, M.; Pers, T.H.; Peters, A.; Rung, J.; Smit, J.H.; Steinthorsdottir, V.; Tobin, M.D.; Tsernikova, N.; Leeuwen, E.M. van; Viikari, J.S.; Willems, S.M.; Willemsen, G.; Schunkert, H.; Erdmann, J.; Samani, N.J.; Kaprio, J.; Lind, L.; Gieger, C.; Metspalu, A.; Slagboom, P.E.; Groop, L.; Duijn, C.M. van; Eriksson, J.G.; Jula, A.; Salomaa, V.; Boomsma, D.I.; Power, C.; Raitakari, O.T.; Ingelsson, E.; Jarvelin, M.R.; Thorsteinsdottir, U.; Franke, L.; Ikonen, E.; Kallioniemi, O.; Pietiainen, V.; Lindgren, C.M.; Stefansson, K.; Palotie, A.; McCarthy, M.I.; Morris, A.P.; Prokopenko, I.; Ripatti, S. & ENGAGE Consortium (2015), The impact of low-frequency and rare variants on lipid levels, Nature Genetics 47(6): 589-597.
- Hollander, W. den; Pulyakhina, I.; Bomer, N.; Ramos, Y.F.; Breggen, R. van der; Bos, S.; Hoen, P.B.A. 't; Slagboom, E.P.; Nelissen, R.G. & Meulenbelt, I. (2015), PROBING THE ARTICULAR CARTILAGE TRANSCRIPTOME FOR GENETIC OSTEOARTHRITIS SUSCEPTIBLITY, Osteoarthritis and Cartilage 23: A190-A191.
- Postmus, I.; Deelen, J.; Sedaghat, S.; Trompet, S.; Craen, A.J.M. de; Heijmans, B.T.; Franco, O.H.; Hofman, A.; Dehghan, A.; Slagboom, P.E.; Westendorp, R.G.J. & Jukema, J.W. (2015), LDL cholesterol still a problem in old age? A Mendelian randomization study, International Journal of Epidemiology 44(2): 604-612.
- Hollander, W. den; Ramos, Y.F.; Bomer, N.; Elzinga, S.; Breggen, R. van der; Lakenberg, N.; Dijcker, W.J. de; Suchiman, E.H.; Duijnisveld, B.J.; Bohringer, S.; Houwing-Duistermaat, J.J.; Slagboom, E.P.; Bos, S.D.; Nelissen, R.G. & Meulenbelt, I. (2015), DISCRIMINATING BETWEEN PUTATIVE EPIGENETIC OSTEOARTHRITIS DISEASE DRIVERS AND SHEER MARKERS, Osteoarthritis and Cartilage 23: A190-A190.
- Bomer, N.; Cornelis, F.M.; Ramos, Y.F.; Hollander, W. den; Storms, L.; Breggen, R. van der; Lakenberg, N.; Slagboom, P.E.; Meulenbelt, I. & Lories, R.J. (2015), DIO2-DEFICIENT MICE ARE PROTECTED AGAINST CARTILAGE DAMAGE IN A MODEL OF EXERCISE-INDUCED OA, Osteoarthritis and Cartilage 23: A37-A38.
- Ramos, Y.F.; Hollander, W. den; Lakenberg, N.; Breggen, R. van der; Bomer, N.; Kroon, H.; Kloppenburg, M.; Slagboom, P. & Meulenbelt, I. (2015), RISK PREDICTION USING EPIGENETIC PROFILES IN BLOOD OF OSTEOARTHRITIS PATIENTS, Osteoarthritis and Cartilage 23: A73-A74.
- Peters, M.J.; Joehanes, R.; Pilling, L.C.; Schurmann, C.; Conneely, K.N.; Powell, J.; Reinmaa, E.; Sutphin, G.L.; Zhernakova, A.; Schramm, K.; Wilson, Y.A.; Kobes, S.; Tukiainen, T.; Ramos, Y.F.; Goring, H.H.H.; Fornage, M.; Liu, Y.M.; Gharib, S.A.; Stranger, B.E.; Jager, P.L. de; Aviv, A.; Levy, D.; Murabito, J.M.; Munson, P.J.; Huan, T.; Hofman, A.; Uitterlinden, A.G.; Rivadeneira, F.; Rooij, J. van; Stolk, L.; Broer, L.; Verbiest, M.M.P.J.; Jhamai, M.; Arp, P.; Metspalu, A.; Tserel, L.; Milani, L.; Samani, N.J.; Peterson, P.; Kasela, S.; Codd, V.; Peters, A.; Ward-Caviness, C.K.; Herder, C.; Waldenberger, M.; Roden, M.; Singmann, P.; Zeilinger, S.; Illig, T.; Homuth, G.; Grabe, H.J.; Voelzke, H.; Steil, L.; Kocher, T.; Murray, A.; Melzer, D.; Yaghootkar, H.; Bandinelli, S.; Moses, E.K.; Kent, J.W.; Curran, J.E.; Johnson, M.P.; Williams-Blangero, S.; Westra, H.J.; Mcrae, A.F.; Smith, J.A.; Kardia, S.L.R.; Hovatta, I.; Perola, M.; Ripatti, S.; Salomaa, V.; Henders, A.K.; Martin, N.G.; Smith, A.K.; Mehta, D.; Binder, E.B.; Nylocks, K.M.; Kennedy, E.M.; Klengel, T.; Ding, J.; Suchy-Dicey, A.M.; Enquobahrie, D.A.; Brody, J.; Rotter, J.I.; Chen, Y.D.I.; Houwing-Duistermaat, J.; Kloppenburg, M.; Slagboom, P.E.; Helmer, Q.; Hollander, W. den; Bean, S.; Raj, T.; Bakhshi, N.; Wang, Q.P.; Oyston, L.J.; Psaty, B.M.; Tracy, R.P.; Montgomery, G.W.; Turner, S.T.; Blangero, J.; Meulenbelt, I.; Ressler, K.J.; Yang, J.; Franke, L.; Kettunen, J.; Visscher, P.M.; Neely, G.G.; Korstanje, R.; Hanson, R.L.; Prokisch, H.; Ferrucci, L.; Esko, T.; Teumer, A.; Meurs, J.B.J. van; Andrew, D. & NABEC UKBEC Consortium (2015), The transcriptional landscape of age in human peripheral blood, Nature Communications 6.
- Spoel, E. van der; Rozing, M.P.; Houwing-Duistermaat, J.J.; Slagboom, P.E.; Beekman, M.; Craen, A.J.M. de; Westendorp, R.G.J. & Heemst, D. van (2015), Association analysis of insulin-like growth factor-1 axis parameters with survival and functional status in nonagenarians of the Leiden Longevity Study, Aging 7(11): 956-963.
- Bousquet, J.; Anto, J.M.; Berkouk, K.; Gergen, P.; Antunes, J.P.; Auge, P.; Camuzat, T.; Bringer, J.; Mercier, J.; Best, N.; Bourret, R.; Akdis, M.; Arshad, S.H.; Bedbrook, A.; Berr, C.; Bush, A.; Cavalli, G.; Charles, M.A.; Clavel-Chapelon, F.; Gillman, M.; Gold, D.R.; Goldberg, M.; Holloway, J.W.; Iozzo, P.; Jacquemin, S.; Jeandel, C.; Kauffmann, F.; Keil, T.; Koppelman, G.H.; Krauss-Etschmann, S.; Kuh, D.; Lehmann, S.; Carlsen, K.C.L.; Maier, D.; Mechali, M.; Melen, E.; Moatti, J.P.; Momas, I.; Nerin, P.; Postma, D.S.; Ritchie, K.; Robine, J.M.; Samolinski, B.; Siroux, V.; Slagboom, P.E.; Smit, H.A.; Sunyer, J.; Valenta, R.; Perre, P. van de; Verdier, J.M.; Vrijheid, M.; Wickman, M.; Yiallouros, P. & Zins, M. (2015), Developmental determinants in non-communicable chronic diseases and ageing, Thorax 70(6): 595-597.
- Horikoshi, M.; Magi, R.; Bunt, M. van de; Surakka, I.; Sarin, A.P.; Mahajan, A.; Marullo, L.; Thorleifsson, G.; Hagg, S.; Hottenga, J.J.; Ladenvall, C.; Ried, J.S.; Winkler, T.W.; Willems, S.M.; Pervjakova, N.; Esko, T.; Beekman, M.; Nelson, C.P.; Willenborg, C.; Wiltshire, S.; Ferreira, T.; Fernandez, J.; Gaulton, K.J.; Steinthorsdottir, V.; Hamsten, A.; Magnusson, P.K.E.; Willemsen, G.; Milaneschi, Y.; Robertson, N.R.; Groves, C.J.; Bennett, A.J.; Lehtimaki, T.; Viikari, J.S.; Rung, J.; Lyssenko, V.; Perola, M.; Heid, I.M.; Herder, C.; Grallert, H.; Muller-Nurasyid, M.; Roden, M.; Hypponen, E.; Isaacs, A.; Leeuwen, E.M. van; Karssen, L.C.; Mihailov, E.; Houwing-Duistermaat, J.J.; Craen, A.J.M. de; Deelen, J.; Havulinna, A.S.; Blades, M.; Hengstenberg, C.; Erdmann, J.; Schunkert, H.; Kaprio, J.; Tobin, M.D.; Samani, N.J.; Lind, L.; Salomaa, V.; Lindgren, C.M.; Slagboom, P.E.; Metspalu, A.; Duijn, C.M. van; Eriksson, J.G.; Peters, A.; Gieger, C.; Jula, A.; Groop, L.; Raitakari, O.T.; Power, C.; Penninx, B.W.J.H.; Geus, E. de; Smit, J.H.; Boomsma, D.I.; Pedersen, N.L.; Ingelsson, E.; Thorsteinsdottir, U.; Stefansson, K.; Ripatti, S.; Prokopenko, I.; McCarthy, M.I.; Morris, A.P. & Engage Consortium (2015), Discovery and Fine-Mapping of Glycaemic and Obesity-Related Trait Loci Using High-Density Imputation, PLoS Genetics 11(7).
- Bomer, N.; Cornelis, F.M.; Ramos, Y.F.; Hollander, W. den; Lakenberg, N.; Breggen, R. van der; Storms, L.; Slagboom, P.E.; Lories, R.J. & Meulenbelt, I. (2015), DIO2-KNOCKOUT MODULATES CIRCADIAN CLOCK GENES IN ARTICULAR CARTILAGE THROUGH THYROID HORMONE SIGNALING, Osteoarthritis and Cartilage 23: A67-A67.
- Kloosterman, W.P.; Francioli, L.C.; Hormozdiari, F.; Marschall, T.; Hehir-Kwa, J.Y.; Abdellaoui, A.; Lameijer, E.W.; Moed, M.H.; Koval, V.; Renkens, I.; Roosmalen, M.J. van; Arp, P.; Karssen, L.C.; Coe, B.P.; Handsaker, R.E.; Suchiman, E.D.; Cuppen, E.; Thung, D.T.; McVey, M.; Wendl, M.C.; Uitterlinden, A.; Duijn, C.M. van; Swertz, M.A.; Wijmenga, C.; Ommen, G.B. van; Slagboom, P.E.; Boomsma, D.I.; Schonhuth, A.; Eichler, E.E.; Bakker, P.I.W. de; Ye, K.; Guryev, V. & Genome Netherlands Consortium (2015), Characteristics of de novo structural changes in the human genome, Genome Research 25(6): 792-801.
- Luijk, R.; Goeman, J.J.; Slagboom, E.P.; Heijmans, B.T. & Zwet, E.W. van (2015), An alternative approach to multiple testing for methylation QTL mapping reduces the proportion of falsely identified CpGs, Bioinformatics 31(3): 340-345.
- Jacobs, L.C.; Hamer, M.A.; Gunn, D.A.; Deelen, J.; Lall, J.S.; Heemst, D. van; Uh, H.W.; Hofman, A.; Uitterlinden, A.G.; Griffiths, C.E.M.; Beekman, M.; Slagboom, P.E.; Kayser, M.; Liu, F. & Nijsten, T. (2015), A Genome-Wide Association Study Identifies the Skin Color Genes IRF4, MC1R, ASIP, and BNC2 Influencing Facial Pigmented Spots, Journal of Investigative Dermatology 135(7): 1735-1742.
- Francioli, L.C.; Polak, P.P.; Koren, A.; Menelaou, A.; Chun, S.; Renkens, I.; Duijn, C.M. van; Swertz, M.; Wijmenga, C.; Ommen, G. van; Slagboom, P.E.; Boomsma, D.I.; Ye, K.; Guryev, V.; Arndt, P.F.; Kloosterman, W.P.; Bakker, P.I.W. de; Sunyaev, S.R. & Genome Netherlands Consortium (2015), Genome-wide patterns and properties of de novo mutations in humans, Nature Genetics 47(7): 822-+.
- Pedersen, J.K.; Skytthe, A.; McGue, M.; Honig, L.S.; Franceschi, C.; Kirkwood, T.B.L.; Passarino, G.; Slagboom, P.E.; Vaupel, J.W. & Christensen, K. (2015), Low tobacco-related cancer incidence in offspring of long-lived siblings: a comparison with Danish national cancer registry data, Annals of Epidemiology 25(8): 569-574.
- Burkle, A.; Moreno-Villanueva, M.; Bernhard, J.; Blasco, M.; Zondag, G.; Hoeijmakers, J.H.J.; Toussaint, O.; Grubeck-Loebenstein, B.; Mocchegiani, E.; Collino, S.; Gonos, E.S.; Sikora, E.; Gradinaru, D.; Dolle, M.; Salmon, M.; Kristensen, P.; Griffiths, H.R.; Libert, C.; Grune, T.; Breusing, N.; Simm, A.; Franceschi, C.; Capri, M.; Talbot, D.; Caiafa, P.; Friguet, B.; Slagboom, P.E.; Hervonen, A.; Hurme, M. & Aspinall, R. (2015), MARK-AGE biomarkers of ageing, Mechanisms of Ageing and Development 151: 2-12.
- Drielen, K. van; Gunn, D.A.; Griffiths, C.E.M.; Griffiths, T.W.; Ogden, S.; Noordam, R.; Slagboom, P.E.; Heemst, D. van & Craen, A.J.M. de (2015), Markers of health and disease and pigmented spots in a middle-aged population, British Journal of Dermatology 173(6): 1550-1552.
- Leeuwen, E.M. van; Kanterakis, A.; Deelen, P.; Kattenberg, M.V.; Slagboom, P.E.; Bakker, P.I.W. de; Wijmenga, C.; Swertz, M.A.; Boomsma, D.I.; Duijn, C.M. van; Karssen, L.C.; Hottenga, J.J. & Genome Netherlands Consortium (2015), Population-specific genotype imputations using minimac or IMPUTE2, Nature Protocols 10(9): 1285-1296.
- Winkler, T.W.; Justice, A.E.; Graff, M.; Barata, L.; Feitosa, M.F.; Chu, S.; Czajkowski, J.; Esko, T.; Fall, T.; Kilpelainen, T.O.; Lu, Y.C.; Magi, R.; Mihailov, E.; Pers, T.H.; Rueger, S.; Teumer, A.; Ehret, G.B.; Ferreira, T.; Heard-Costa, N.L.; Karjalainen, J.; Lagou, V.; Mahajan, A.; Neinast, M.D.; Prokopenko, I.; Simino, J.; Teslovich, T.M.; Jansen, R.; Westra, H.J.; White, C.C.; Absher, D.; Ahluwalia, T.S.; Ahmad, S.; Albrecht, E.; Alves, A.C.; Bragg-Gresham, J.L.; Craen, A.J.M. de; Bis, J.C.; Bonnefond, A.; Boucher, G.; Cadby, G.; Cheng, Y.C.; Chiang, C.W.K.; Delgado, G.; Demirkan, A.; Dueker, N.; Eklund, N.; Eiriksdottir, G.; Eriksson, J.; Feenstra, B.; Fischer, K.; Frau, F.; Galesloot, T.E.; Geller, F.; Goel, A.; Gorski, M.; Grammer, T.B.; Gustafsson, S.; Haitjema, S.; Hottenga, J.J.; Huffman, J.E.; Jackson, A.U.; Jacobs, K.B.; Johansson, A.; Kaakinen, M.; Kleber, M.E.; Lahti, J.; Leach, I.M.; Lehne, B.; Liu, Y.F.; , K.S. lo; Lorentzon, M.; Luan, J.; Madden, P.A.F.; Mangino, M.; McKnight, B.; Medina-Gomez, C.; Monda, K.L.; Montasser, M.E.; Muller, G.; Muller-Nurasyid, M.; Nolte, I.M.; Panoutsopoulou, K.; Pascoe, L.; Paternoster, L.; Rayner, N.W.; Renstrom, F.; Rizzi, F.; Rose, L.M.; Ryan, K.A.; Salo, P.; Sanna, S.; Scharnagl, H.; Shi, J.X.; Smith, A.V.; Southam, L.; Stancakova, A.; Steinthorsdottir, V.; Strawbridge, R.J.; Sung, Y.J.; Tachmazidou, I.; Tanaka, T.; Thorleifsson, G.; Trompet, S.; Pervjakova, N.; Tyrer, J.P.; Vandenput, L.; Laan, S.W. van der; Velde, N. van der; Setten, J. van; Vliet-Ostaptchouk, J.V. van; Verweij, N.; Vlachopoulou, E.; Waite, L.L.; Wang, S.R.; Wang, Z.M.; Wild, S.H.; Willenborg, C.; Wilson, J.F.; Wong, A.; Yang, J.; Yengo, L.; Yerges-Armstrong, L.M.; Yu, L.; Zhang, W.H.; Zhao, J.H.; Andersson, E.A.; Bakker, S.J.L.; Baldassarre, D.; Banasik, K.; Barcella, M.; Barlassina, C.; Bellis, C.; Benaglio, P.; Blangero, J.; Bluher, M.; Bonnet, F.; Bonnycastle, L.L.; Boyd, H.A.; Bruinenberg, M.; Buchman, A.S.; Campbell, H.; Chen, Y.D.I.; Chines, P.S.; Claudi-Boehm, S.; Cole, J.; Collins, F.S.; Geus, E.J.C. de; Groot, L.C.P.G.M. de; Dimitriou, M.; Duan, J.; Enroth, S.; Eury, E.; Farmaki, A.E.; Forouhi, N.G.; Friedrich, N.; Gejman, P.V.; Gigante, B.; Glorioso, N.; Go, A.S.; Gottesman, O.; Grassler, J.; Grallert, H.; Grarup, N.; Gu, Y.M.; Broer, L.; Ham, A.C.; Hansen, T.; Harris, T.B.; Hartman, C.A.; Hassinen, M.; Hastie, N.; Hattersley, A.T.; Heath, A.C.; Henders, A.K.; Hernandez, D.; Hillege, H.; Holmen, O.; Hovingh, K.G.; Hui, J.; Husemoen, L.L.; Hutri-Kahonen, N.; Hysi, P.G.; Illig, T.; Jager, P.L. de; Jalilzadeh, S.; Jorgensen, T.; Jukema, J.W.; Juonala, M.; Kanoni, S.; Karaleftheri, M.; Khaw, K.T.; Kinnunen, L.; Kittner, S.J.; Koenig, W.; Kolcic, I.; Kovacs, P.; Krarup, N.T.; Kratzer, W.; Kruger, J.; Kuh, D.; Kumari, M.; Kyriakou, T.; Langenberg, C.; Lannfelt, L.; Lanzani, C.; Lotay, V.; Launer, L.J.; Leander, K.; Lindstrom, J.; Linneberg, A.; Liu, Y.P.; Lobbens, S.; Luben, R.; Lyssenko, V.; Mannisto, S.; Magnusson, P.K.; McArdle, W.L.; Menni, C.; Merger, S.; Milani, L.; Montgomery, G.W.; Morris, A.P.; Narisu, N.; Nelis, M.; Ong, K.K.; Palotie, A.; Perusse, L.; Pichler, I.; Pilia, M.G.; Pouta, A.; Rheinberger, M.; Ribel-Madsen, R.; Richards, M.; Rice, K.M.; Rice, T.K.; Rivolta, C.; Salomaa, V.; Sanders, A.R.; Sarzynski, M.A.; Scholtens, S.; Scott, R.A.; Scott, W.R.; Sebert, S.; Sengupta, S.; Sennblad, B.; Seufferlein, T.; Silveira, A.; Slagboom, P.E.; Smit, J.H.; Sparso, T.H.; Stirrups, K.; Stolk, R.P.; Stringham, H.M.; Swertz, M.A.; Swift, A.J.; Syvanen, A.C.; Tan, S.T.; Thorand, B.; Tonjes, A.; Tremblay, A.; Tsafantakis, E.; Most, P.J. van der; Volker, U.; Vohl, M.C.; Vonk, J.M.; Waldenberger, M.; Walker, R.W.; Wennauer, R.; Widen, E.; Willemsen, G.; Wilsgaard, T.; Wright, A.F.; Zillikens, M.C.; Dijk, S.C. van; Schoor, N.M. van; Asselbergs, F.W.; Bakker, P.I.W. de; Beckmann, J.S.; Beilby, J.; Bennett, D.A.; Bergman, R.N.; Bergmann, S. & Boger, C.A (2015), The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape: A Large-Scale Genome-Wide Interaction Study, PLoS Genetics 11(10).
- Hillger, J.M.; Schoop, J.; Boomsma, D.I.; Slagboom, P.E.; Ijzerman, A.P. & Heitman, L.H. (2015), Whole-cell biosensor for label-free detection of GPCR-mediated drug responses in personal cell lines, Biosensors and Bioelectronics 74: 233-242.
- Locke, A.E.; Kahali, B.; Berndt, S.I.; Justice, A.E.; Pers, T.H.; Felix, R.; Powell, C.; Vedantam, S.; Buchkovich, M.L.; Yang, J.; Croteau-Chonka, D.C.; Esko, T.; Fall, T.; Ferreira, T.; Gustafsson, S.; Kutalik, Z.; Luan, J.A.; Magi, R.; Randall, J.C.; Winkler, T.W.; Wood, A.R.; Workalemahu, T.; Faul, J.D.; Smith, J.A.; Zhao, J.H.; Zhao, W.; Chen, J.; Fehrmann, R.; Hedman, A.K.; Karjalainen, J.; Schmidt, E.M.; Absher, D.; Amin, N.; Anderson, D.; Beekman, M.; Bolton, J.L.; Bragg-Gresham, L.; Buyske, S.; Demirkan, A.; Deng, G.H.; Ehret, G.B.; Feenstra, B.; Feitosa, M.F.; Fischer, K.; Goel, A.; Gong, J.; Jackson, A.U.; Kanoni, S.; Kleber, M.E.; Kristiansson, K.; Lim, U.; Lotay, V.; Mangino, M.; Leach, I.M.; Medina-Gomez, C.; Medland, S.E.; Nalls, M.A.; Palmer, C.D.; Pasko, D.; Pechlivanis, S.; Peters, M.J.; Prokopenko, I.; Shungin, D.; Stancakova, A.; Strawbridge, R.J.; Sung, Y.J.; Tanaka, T.; Teumer, A.; Trompet, S.; Laan, S.W. van der; Settee, J. van; Vliet-Ostaptchouk, J.V. van; Wang, Z.M.; Yengo, L.; Zhang, W.H.; Isaacs, A.; Albrecht, E.; Arnlov, J.; Arscott, G.M.; Attwood, A.P.; Bandinelli, S.; Barrett, A.; Bas, I.N.; Bellis, C.; Bennett, A.J.; Berne, C.; Blagieva, R.; Bluher, M.; Bohringer, S.; Bonnycastle, L.L.; Bottcher, Y.; Boyd, H.A.; Bruinenberg, M.; Caspersen, I.H.; Chen, Y.D.; Clarke, R.; Daw, E.W.; Craen, A.J.M. de; Delgado, G.; Dimitriou, M.; Doney, A.S.F.; Eklund, N.; Estrada, K.; Eury, E.; Folkersen, L.; Fraser, R.M.; Garcia, M.E.; Geller, F.; Giedraitis, V.; Gigante, B.; Go, A.S.; Golay, A.; Goodall, A.H.; Gordon, S.D.; Gorski, M.; Grabe, H.J.; Grallert, H.; Grammer, T.B.; Grassler, J.; Gronberg, H.; Groves, C.J.; Gusto, G.; Haessler, J.; Hall, P.; Haller, T.; Hallmans, G.; Hartman, C.A.; Hassinen, M.; Hayward, C.; Heard-Costa, N.L.; Helmer, Q.; Hengstenberg, C.; Holmen, O.; Hottenga, J.J.; James, A.L.; Jeff, J.M.; Johansson, A.; Jolley, J.; Juliusdottir, T.; Kinnunen, L.; Koenig, W.; Koskenvuo, M.; Kratzer, W.; Laitinen, J.; Lamina, C.; Leander, K.; Lee, N.R.; Lichtner, P.; Lind, L.; Lindstrom, J.; , K.S. lo; Lobbens, S.; Lorbeer, R.; Lu, Y.C.; Mach, F.; Magnusson, P.K.E.; Mahajan, A.; McArdle, W.L.; McLachlan, S.; Menni, C.; Merger, S.; Mihailov, E.; Milani, L.; Moayyeri, A.; Monda, K.L.; Morken, M.A.; Mulas, A.; Muller, G.; Muller-Nurasyid, M.; Musk, A.W.; Nagaraja, R.; Nothen, M.M.; Nolte, I.M.; Pilz, S.; Rayner, N.W.; Renstrom, F.; Rettig, R.; Ried, J.S.; Ripke, S.; Robertson, N.R.; Rose, L.M.; Sanna, S.; Scharnagl, H.; Scholtens, S.; Schumacher, F.R.; Scott, W.R.; Seufferlein, T.; Shi, J.X.; Smith, A.V.; Smolonska, J.; Stanton, A.V.; Steinthorsdottir, V.; Stirrups, K.; Stringham, H.M.; Sundstrom, J.; Swertz, M.A.; Swift, A.J.; Syvanen, A.C.; Tan, S.T.; Tayo, B.O.; Thorand, B.; Thorleifsson, G.; Tyrer, J.P.; Uh, H.W.; Vandenput, L.; Verhulst, F.C.; Vermeulen, S.H.; Verweij, N.; Vonk, J.M.; Waite, L.L.; Warren, H.R.; Waterworth, D.; Weedon, M.N.; Wilkens, L.R.; Willenborg, C.; Wilsgaard, T.; Wojczynski, M.K.; Wong, A.; Wrightl, A.F.; Zhang, Q.Y.; Brennan, E.P.; Choi, M.; Dastani, Z.; Drong, A.W.; Eriksson, P.; Franco-Cereceda, A.; Gadin, J.R.; Gharavi, A.G.; Goddard, M.E.; Handsaker, R.E.; Huang, J.Y.; Karpe, F.; Kathiresan, S.; Keildson, S.; Kiryluk, K.; Kubo, M.; Lee, J.Y.; Liang, L.; Lifton, R.P.; Ma, B.S.; McCarroll, S.A.; McKnight, A.J.; Min, J.L.; Moffatt, M.F.; Montgomery, G.W.; Murabito, J.M.; Nicholson, G.; Nyholt, D.R.; Okada, Y.; Perry, J.R.B.; Dorajoo, R.; Reinmaa, E.; Salem, R.M.; Sandholm, N.; Scott, R.A.; Stolk, L.; Takahashi, A.; Tanaka, T.; Hooft, F.M. van 't; Vinkhuyzen, A.A.E.; Westra, H.J.; Zheng, W.; Zondervan, K.T.; Heath, A.C.; Arveiler, D.; Bakker, S.J.L.; Beilby, J.; Bergman, R.N.; Blangero, J.; Bovet, P.; Campbell, H.; Caulfield, M.J.; Cesana, G.; Chakravarti, A.; Chasman, D.I.; Chines, P.S.; Collins, F.S.; Crawford, D.C.; Cupples, L.A.; Cusi, D.; Danesh, J.; Faire, U. de; Ruijter, H.M. den; Dominiczak, A.F.; Erbel, R.; Erdmann, J. & (2015), Genetic studies of body mass index yield new insights for obesity biology, Nature 518(7538): 197-U401.
- Hollander, W. den; Ramos, Y.F.M.; Bomer, N.; Elzinga, S.; Breggen, R. van der; Lakenberg, N.; Dijcker, W.J. de; Suchiman, H.E.D.; Duijnisveld, B.J.; Houwing-Duistermaat, J.J.; Slagboom, P.E.; Bos, S.D.; Nelissen, R.G.H.H. & Meulenbelt, I. (2015), Transcriptional Associations of Osteoarthritis-Mediated Loss of Epigenetic Control in Articular Cartilage, Arthritis and Rheumatology 67(8): 2108-2116.
- Shungin, D.; Winkler, T.W.; Croteau-Chonka, D.C.; Ferreira, T.; Lockes, A.E.; Magi, R.; Strawbridge, R.J.; Pers, T.H.; Fischer, K.; Justice, A.E.; Workalemahu, T.; Wu, J.M.W.; Buchkovich, M.L.; Heard-Costa, N.L.; Roman, T.S.; Drong, A.W.; Song, C.; Gustafsson, S.; Day, F.R.; Esko, T.; Fall, T.; Kutalik, Z.; Luan, J.A.; Randall, J.C.; Scherag, A.; Vedantam, S.; Wood, A.R.; Chen, J.; Fehrmann, R.; Karjalainen, J.; Kahali, B.; Liu, C.T.; Schmidt, E.M.; Absher, D.; Amin, N.; Anderson, D.; Beekman, M.; Bragg-Gresham, J.L.; Buyske, S.; Demirkan, A.; Ehret, G.B.; Feitosa, M.F.; Goel, A.; Jackson, A.U.; Johnson, T.; Kleber, M.E.; Kristiansson, K.; Mangino, M.; Leach, I.M.; Medina-Gomez, C.; Palmer, C.D.; Pasko, D.; Pechlivaniss, S.; Peters, M.J.; Prokopenko, I.; Stancakova, A.; Sung, Y.J.; Tanakam, T.; Teumer, A.; Vliet-Ostaptchouk, J.V. van; Yengo, L.; Zhang, W.H.; Albrecht, E.; Arnlov, J.; Arscott, G.M.; Bandinelli, S.; Barrett, A.; Bellis, C.; Bennett, A.J.; Berne, C.; Bluher, M.; Buhringer, S.; Bonnet, F.; Bottcher, Y.; Bruinenberg, M.; Carba, D.B.; Caspersen, I.H.; Clarke, R.; Daw, E.W.; Deelen, J.; Deelman, E.; Delgado, G.; Doney, A.S.F.; Eklund, N.; Erdos, M.R.; Estrada, K.; Eury, E.; Friedrichs, N.; Garcia, M.E.; Giedraitis, V.; Gigante, B.; Go, A.S.; Golay, A.; Grallert, H.; Grammer, T.B.; Grassler, J.; Grewal, J.; Groves, C.J.; Haller, T.; Hallmans, G.; Hartman, C.A.; Hassinen, M.; Hayward, C.; Heikkila, K.; Herzig, K.H.; Helmer, Q.; Hillege, H.L.; Holmen, O.; Hunt, S.C.; Isaacs, A.; Ittermann, T.; James, A.L.; Johansson, I.; Juliusdottir, T.; Kalafati, I.P.; Kinnunen, L.; Koenig, W.; Kooner, I.K.; Kratzer, W.; Lamina, C.; Leander, K.; Lee, N.R.; Lichtner, P.; Lind, L.; Lindstrom, J.; Lobbens, S.; Lorentzon, M.; Mach, F.; Magnusson, P.K.E.; Mahajan, A.; McArdle, W.L.; Menni, C.; Merger, S.; Mihailov, E.; Milani, L.; Mills, R.; Moayyeri, A.; Monda, K.L.; Mooijaart, S.P.; Muhleisen, T.W.; Mulas, A.; Muller, G.; Muller-Nurasyid, M.; Nagaraja, R.; Nalls, M.A.; Narisu, N.; Glorioso, N.; Nolte, I.M.; Olden, M.; Rayner, N.W.; Renstrom, F.; Ried, J.S.; Robertson, N.R.; Rose, L.M.; Sanna, S.; Scharnagl, H.; Scholtens, S.; Sennblad, B.; Seufferlein, T.; Sitlani, C.M.; Smith, A.V.; Stirrups, K.; Stringhams, H.M.; Sundstrom, J.; Swertz, M.A.; Swift, A.J.; Syvanen, A.C.; Tayo, B.O.; Thorand, B.; Thorleifsson, G.; Tomaschitz, A.; Troffa, C.; Oort, F.V.A. van; Verweij, N.; Vonk, J.M.; Waite, L.L.; Wennauer, R.; Wilsgaard, T.; Wojczynski, M.K.; Wong, A.; Zhang, Q.Y.; Zhao, J.H.; Brennan, E.P.; Choi, M.; Eriksson, P.; Folkersen, L.; Franco-Cereceda, A.; Gharavi, A.G.; Hedman, A.K.; Hivert, M.F.; Huang, J.Y.; Kanoni, S.; Karpe, F.; Keildson, S.; Kiryluk, K.; Liang, L.M.; Lifton, R.P.; Ma, B.S.; McKnight, A.J.; McPherson, R.; Metspalu, A.; Min, J.L.; Moffatt, M.F.; Montgomery, G.W.; Murabito, J.M.; Nicholson, G.; Nyholt, D.R.; Olsson, C.; Perry, J.R.B.; Reinmaa, E.; Salem, R.M.; Sandholm, N.; Schadt, E.E.; Scott, R.; Stolk, L.; Vallejo, E.E.; Westra, H.J.; Zondervan, K.T.; Amouyel, P.; Arveiler, D.; Bakker, S.J.L.; Beilby, J.; Bergman, R.N.; Blangero, J.; Brown, M.J.; Burnier, M.; Campbell, H.; Chakravarti, A.; Chiness, P.S.; Claudi-Boehmi, S.; Collins, F.S.; Crawford, D.C.; Danesh, J.; Faire, U. de; Geusl, E.J.C. de; Dorr, M.; Erbel, R.; Eriksson, J.G.; Farrall, M.; Ferrannini, E.; Ferrieres, J.; Forouhi, N.G.; Forrester, T.; Franco, O.H.; Gansevoort, R.T.; Gieger, C.; Gudnason, V.; Haiman, C.A.; Harris, T.B.; Hattersley, A.T.; Heliovaara, M.; Hicks, A.A.; Hingorani, A.D.; Hoffmann, W.; Hofman, A.; Homuth, G.; Humphries, S.E.; Hypponen, E.; Illig, T.; Jarvelin, M.R.; Johansen, B.; Jousilahti, P.; Jula, A.M.; Kaprio, J.; Kee, F.; Keinanen-Kiukaanniemi, S.M.; Kooner, J.S.; Kooperberg, C.; Kovacs, P.; Kraja, A.T.; Kumari, M.; Kuulasmaa, K.; Kuusisto, J.; Lakka, T.A.; Langenberg, C.; Marchand, L. le; Lehtimaki, T.; Lyssenko, V.; Mannisto, S.; Marette, A.; Matise, T.C.; McKenzie, C.A. & McKnight, B. (2015), New genetic loci link adipose and insulin biology to body fat distribution, Nature 518(7538): 187-U378.
- Dongen, J. van; Willemsen, G.; Heijmans, B.T.; Neuteboom, J.; Kluft, C.; Jansen, R.; Penninx, B.W.J.; Slagboom, P.E.; Geus, E.J.C. de & Boomsma, D.I. (2015), Longitudinal weight differences, gene expression and blood biomarkers in BMI-discordant identical twins, International Journal of Obesity 39(6): 899-909.
- Passtoors, W.M.; Akker, E.B. van den; Deelen, J.; Maier, A.B.; Breggen, R. van der; Jansen, R.; Trompet, S.; Heemst, D. van; Derhovanessian, E.; Pawelec, G.; Ommen, G.J.B. van; Slagboom, P.E. & Beekman, M. (2015), IL7R gene expression network associates with human healthy ageing, Immunity and Ageing 12.
- Broer, L.; Buchman, A.S.; Deelen, J.; Evans, D.S.; Faul, J.D.; Lunetta, K.L.; Sebastiani, P.; Smith, J.A.; Smith, A.V.; Tanaka, T.; Yu, L.; Arnold, A.M.; Aspelund, T.; Benjamin, E.J.; Jager, P.L. de; Eirkisdottir, G.; Evans, D.A.; Garcia, M.E.; Hofman, A.; Kaplan, R.C.; Kardia, S.L.R.; Kiel, D.P.; Oostra, B.A.; Orwoll, E.S.; Parimi, N.; Psaty, B.M.; Rivadeneira, F.; Rotter, J.I.; Seshadri, S.; Singleton, A.; Tiemeier, H.; Uitterlinden, A.G.; Zhao, W.; Bandinelli, S.; Bennett, D.A.; Ferrucci, L.; Gudnason, V.; Harris, T.B.; Karasik, D.; Launer, L.J.; Perls, T.T.; Slagboom, P.E.; Tranah, G.J.; Weir, D.R.; Newman, A.B.; Duijn, C.M. van & Murabito, J.M. (2015), GWAS of Longevity in CHARGE Consortium Confirms APOE and FOXO3 Candidacy, Journals of Gerontology, Series A 70(1): 110-118.
- Leeuwen, E.M. van; Karssen, L.C.; Deelen, J.; Isaacs, A.; Medina-Gomez, C.; Mbarek, H.; Kanterakis, A.; Trompet, S.; Postmus, I.; Verweij, N.; Enckevort, D.J. van; Huffman, J.E.; White, C.C.; Feitosa, M.F.; Bartz, T.M.; Manichaikul, A.; Joshi, P.K.; Peloso, G.M.; Deelen, P.; Dijk, F. van; Willemsen, G.; Geus, E.J. de; Milaneschi, Y.; Penninx, B.W.J.H.; Francioli, L.C.; Menelaou, A.; Pulit, S.L.; Rivadeneira, F.; Hofman, A.; Oostra, B.A.; Franco, O.H.; Leach, I.M.; Beekman, M.; Craen, A.J.M. de; Uh, H.W.; Trochet, H.; Hocking, L.J.; Porteous, D.J.; Sattar, N.; Packard, C.J.; Buckley, B.M.; Brody, J.A.; Bis, J.C.; Rotter, J.I.; Mychaleckyj, J.C.; Campbell, H.; Duan, Q.; Lange, L.A.; Wilson, J.F.; Hayward, C.; Polasek, O.; Vitart, V.; Rudan, I.; Wright, A.F.; Rich, S.S.; Psaty, B.M.; Borecki, I.B.; Kearney, P.M.; Stott, D.J.; Cupples, L.A.; Jukema, J.W.; Harst, P. van der; Sijbrands, E.J.; Hottenga, J.J.; Uitterlinden, A.G.; Swertz, M.A.; Ommen, G.J.B. van; Bakker, P.I.W. de; Slagboom, P.E.; Boomsma, D.I.; Wijmenga, C.; Duijn, C.M. van & Genome Netherlands Consortium (2015), Genome of the Netherlands population-specific imputations identify an ABCA6 variant associated with cholesterol levels, Nature Communications 6.
- Oh, G.; Wang, S.C.; Pal, M.; Chen, Z.F.; Khare, T.; Tochigi, M.; Ng, C.; Yang, Y.A.; Kwan, A.; Kaminsky, Z.A.; Mill, J.; Gunasinghe, C.; Tackett, J.L.; Gottesman, I.I.; Willemsen, G.; Geus, E.J.C. de; Vink, J.M.; Slagboom, P.E.; Wray, N.R.; Heath, A.C.; Montgomery, G.W.; Turecki, G.; Martin, N.G.; Boomsma, D.I.; McGuffin, P.; Kustra, R. & Petronis, A. (2015), DNA Modification Study of Major Depressive Disorder: Beyond Locus-by-Locus Comparisons, Biological Psychiatry 77(3): 246-255.
- Bomer, N.; Hollander, W. den; Ramos, Y.F.M.; Bos, S.D.; Breggen, R. van der; Lakenberg, N.; Pepers, B.A.; Eeden, A.E. van; Darvishan, A.; Tobi, E.W.; Duijnisveld, B.J.; Akker, E.B. van den; Heijmans, B.T.; Roon-Mom, W.M.C. van; Verbeek, F.J.; Osch, G.J.V.M. van; Nelissen, R.G.H.H.; Slagboom, P.E. & Meulenbelt, I. (2015), Underlying molecular mechanisms of DIO2 susceptibility in symptomatic osteoarthritis, Annals of the Rheumatic Diseases 74(8): 1571-1579.
- Akker, E.B. van den; Deelen, J.; Slagboom, P.E.; Beekman, M. & Atzmon, G. (2015), Exome and Whole Genome Sequencing in Aging and Longevity, Advances in Experimental Medicine and Biology 847: 127-139.
- Tobi, E.W.; Slieker, R.C.; Stein, A.D.; Suchiman, H.E.D.; Slagboom, P.E.; Zwet, E.W. van; Heijmans, B.T. & Lumey, L.H. (2015), Early gestation as the critical time-window for changes in the prenatal environment to affect the adult human blood methylome, International Journal of Epidemiology 44(4): 1211-1223.
- Jansen, S.W.; Roelfsema, F.; Spoel, E. van der; Akintola, A.A.; Postmus, I.; Ballieux, B.E.; Slagboom, P.E.; Cobbaert, C.M.; Grond, J. van der; Westendorp, R.G.; Pijl, H. & Heemst, D. van (2015), Familial Longevity Is Associated With Higher TSH Secretion and Strong TSH-fT3 Relationship, Journal of Clinical Endocrinology and Metabolism 100(10): 3806-3813.
- Bomer, N.; Cornelis, F.M.; Ramos, Y.F.; Lakenberg, N.; Breggen, R. van der; Hollander, W. den; Slagboom, P.E.; Lories, R.J. & Meulenbelt, I. (2014), THE EFFECT OF SEVERE EXERCISE ON KNEE-JOINTS: IDENTIFYING PATHWAYS INVOLVED IN CARTILAGE DEGRADATION PROCESSES FOLLOWING MECHANICAL STRESS, Osteoarthritis and Cartilage 22: S311-S312.
- Dane, A.D.; Hendriks, M.M.W.B.; Reijmers, T.H.; Harms, A.C.; Troost, J.; Vreeken, R.J.; Boomsma, D.I.; Duijn, C.M. van; Slagboom, E.P. & Hankemeier, T. (2014), Integrating Metabolomics Profiling Measurements Across Multiple Biobanks, Analytical Chemistry 86(9): 4110-4114.
- Ramos, Y.F.; Bos, S.D.; Breggen, R. van der; Deelen, J.; Kloppenburg, M.; Ye, K.; Beekman, M.; Lameijer, E.W.E.; Nelissen, R.G.; Slagboom, P.E. & Meulenbelt, I. (2014), A GAIN OF FUNCTION MUTATION IN TNFRSF11B CAUSES OSTEOARTHRITIS WITH CHONDROCALCINOSIS, Osteoarthritis and Cartilage 22: S226-S226.
- Rodriguez-Fontenla, C.; Calaza, M.; Evangelou, E.; Valdes, A.M.; Arden, N.; Blanco, F.J.; Carr, A.; Chapman, K.; Deloukas, P.; Doherty, M.; Esko, T.; Aleta, C.M.G.; Carnota, J.J.G.R.; Helgadottir, H.; Hofman, A.; Jonsdottir, I.; Kerkhof, H.J.M.; Kloppenburg, M.; McCaskie, A.; Ntzani, E.E.; Ollier, W.E.R.; Oreiro, N.; Panoutsopoulou, K.; Ralston, S.H.; Ramos, Y.F.; Riancho, J.A.; Rivadeneira, F.; Slagboom, P.E.; Styrkarsdottir, U.; Thorsteinsdottir, U.; Thorleifsson, G.; Tsezou, A.; Uitterlinden, A.G.; Wallis, G.A.; Wilkinson, J.M.; Zhai, G.J.; Zhu, Y.Y.; Felson, D.T.; Ioannidis, J.P.A.; Loughlin, J.; Metspalu, A.; Meulenbelt, I.; Stefansson, K.; Meurs, J.B. van; Zeggini, E.; Spector, T.D.; Gonzalez, A. & arcOGEN Consortium (2014), Assessment of Osteoarthritis Candidate Genes in a Meta-Analysis of Nine Genome-Wide Association Studies, Arthritis and Rheumatology 66(4): 940-949.
- Landt, M.C.T.S.O.; Furth, E.F. van; Meulenbelt, I.; Bartels, M.; Hottenga, J.J.; Slagboom, P.E. & Boomsma, D.I. (2014), Association Study of the Estrogen Receptor I Gene (ESR1) in Anorexia Nervosa and Eating Disorders: No Replication Found.
- Ramos, Y.F.M.; Hollander, W. den; Bovee, J.V.M.G.; Bomer, N.; Breggen, R. van der; Lakenberg, N.; Keurentjes, J.C.; Goeman, J.J.; Slagboom, P.E.; Nelissen, R.G.H.H.; Bos, S.D. & Meulenbelt, I. (2014), Genes Involved in the Osteoarthritis Process Identified through Genome Wide Expression Analysis in Articular Cartilage; the RAAK Study, PLoS ONE 9(7).
- Hollander, W. den; Ramos, Y.F.; Bos, S.D.; Bomer, N.; Breggen, R. van der; Lakenberg, N.; Sliecker, R.; Luijk, R.; Tobi, E.W.; Duijnisveld, B.J.; Akker, E.B. van den; Heijmans, B.T.; Slagboom, P.E.; Nelissen, R.G. & Meulenbelt, I. (2014), GENOME WIDE DNA METHYLATION PROFILING OF OSTEOARTHRITIC ARTICULAR CARTILAGE, Osteoarthritis and Cartilage 22: S40-S41.
- Ramos, Y.F.M.; Bos, S.D.; Lakenberg, N.; Bohringer, S.; Hollander, W.J. den; Kloppenburg, M.; Slagboom, P.E. & Meulenbelt, I. (2014), Genes expressed in blood link osteoarthritis with apoptotic pathways, Annals of the Rheumatic Diseases 73(10): 1844-1853.
- Vaarhorst, A.A.M.; Verhoeven, A.; Weller, C.M.; Bohringer, S.; Goraler, S.; Meissner, A.; Decider, A.M.; Henneman, P.; Gorgels, A.P.M.; Brandt, P.A. van den; Schouten, L.J.; Greevenbroek, M.M. van; Merry, A.H.H.; Verschuren, W.M.M.; Maagdenberg, A.M.J.M. van den; Dijk, K.W. van; Isaacs, A.; Boomsma, D.; Oostra, B.A.; Duijn, C.M. van; Jukema, J.W.; Boer, J.M.A.; Feskens, E.; Heijmans, B.T. & Slagboom, P.E. (2014), A metabolomic profile is associated with the risk of incident coronary heart disease, American Heart Journal 168(1): 45-52.
- Deelen, J.; Beekman, M.; Codd, V.; Trompet, S.; Broer, L.; Hagg, S.; Fischer, K.; Thijssen, P.E.; Suchiman, H.E.D.; Postmus, I.; Uitterlinden, A.G.; Hofman, A.; Craen, A.J.M. de; Metspalu, A.; Pedersen, N.L.; Duijn, C.M. van; Jukema, J.W.; Houwing-Duistermaat, J.J.; Samani, N.J. & Slagboom, P.E. (2014), Leukocyte telomere length associates with prospective mortality independent of immune-related parameters and known genetic markers, International Journal of Epidemiology 43(3): 878-886.
- Deelen, J.; Beekman, M.; Uh, H.W.; Broer, L.; Ayers, K.L.; Tan, Q.; Kamatani, Y.; Bennet, A.M.; Tamm, R.; Trompet, S.; Guobjartsson, D.F.; Flachsbart, F.; Rose, G.; Viktorin, A.; Fischer, K.; Nygaard, M.; Cordell, H.J.; Crocco, P.; Akker, E.B. van den; Bohringer, S.; Helmer, Q.; Nelson, C.P.; Saunders, G.I.; Alver, M.; Andersen-Ranberg, K.; Breen, M.E.; Breggen, R. van der; Caliebe, A.; Capri, M.; Cevenini, E.; Collerton, J.C.; Dato, S.; Davies, K.; Ford, I.; Gampe, J.; Garagnani, P.; Geus, E.J.C. de; Harrow, J.; Heemst, D. van; Heijmans, B.T.; Heinsen, F.A.; Hottenga, J.J.; Hofman, A.; Jeune, B.; Jonsson, P.V.; Lathrop, M.; Lechner, D.; Martin-Ruiz, C.; Mcnerlan, S.E.; Mihailov, E.; Montesanto, A.; Mooijaart, S.P.; Murphy, A.; Nohr, E.A.; Paternoster, L.; Postmus, I.; Rivadeneira, F.; Ross, O.A.; Salvioli, S.; Sattar, N.; Schreiber, S.; Stefansson, H.; Stott, D.J.; Tiemeier, H.; Uitterlinden, A.G.; Westendorp, R.G.J.; Willemsen, G.; Samani, N.J.; Galan, P.; Sorensen, T.I.A.; Boomsma, D.I.; Jukema, J.W.; Rea, I.M.; Passarino, G.; Craen, A.J.M. de; Christensen, K.; Nebel, A.; Stefansson, K.; Metspalu, A.; Magnusson, P.; Blanche, H.; Christiansen, L.; Kirkwood, T.B.L.; Duijn, C.M. van; Franceschi, C.; Houwing-Duistermaat, J.J. & Slagboom, P.E. (2014), Genome-wide association meta-analysis of human longevity identifies a novel locus conferring survival beyond 90 years of age, Human Molecular Genetics 23(16): 4420-4432.
- Ramos, Y.F.M.; Metrustry, S.; Arden, N.; Bay-Jensen, A.C.; Beekman, M.; Craen, A.J.M. de; Cupples, L.A.; Esko, T.; Evangelou, E.; Felson, D.T.; Hart, D.J.; Ioannidis, J.P.A.; Karsdal, M.; Kloppenburg, M.; Lafeber, F.; Metspalu, A.; Panoutsopoulou, K.; Slagboom, P.E.; Spector, T.D.; Spil, E.W.E. van; Uitterlinden, A.G.; Zhu, Y.Y.; Valdes, A.M.; Meurs, J.B.J. van; Meulenbelt, I.; arcOGEN Consortium & TreatOA Collaborators (2014), Meta-analysis identifies loci affecting levels of the potential osteoarthritis biomarkers sCOMP and uCTX-II with genome wide significance, Journal of Medical Genetics 51(9): 596-604.
- Akker, E.B. van den; Passtoors, W.M.; Jansen, R.; Zwet, E.W. van; Goeman, J.J.; Hulsman, M.; Emilsson, V.; Perola, M.; Willemsen, G.; Penninx, B.W.J.H.; Heijmans, B.T.; Maier, A.B.; Boomsma, D.I.; Kok, J.N.; Slagboom, P.E.; Reinders, M.J.T. & Beekman, M. (2014), Meta- analysis on blood transcriptomic studies identifies consistently coexpressed protein- protein interaction modules as robust markers of human aging, Aging Cell 13(2): 216-225.
- Francioli, L.C.; Menelaou, A.; Pulit, S.L.; Dijk, F. van; Palamara, P.F.; Elbers, C.C.; Neerincx, P.B.T.; Ye, K.; Guryev, V.; Kloosterman, W.P.; Deelen, P.; Abdellaoui, A.; Leeuwen, E.M. van; Oven, M. van; Vermaat, M.; Li, M.; Laros, J.F.J.; Karssen, L.C.; Kanterakis, A.; Amin, N.; Hottenga, J.J.; Lameijer, E.W.; Kattenberg, M.; Dijkstra, M.; Byelas, H.; Settenl, J. van; Schaik, B.D.C. van; Bot, J.; Nijman, I.J.; Renkens, I.; Marscha, T.; Schonhuth, A.; Hehir-Kwa, J.Y.; Handsaker, R.E.; Polak, P.; Sohail, M.; Vuzman, D.; Hormozdiari, F.; Enckevort, D. van; Mei, H.; Koval, V.; Moed, M.T.H.; Velde, K.J. van der; Rivadeneira, F.; Estrada, K.; Medina-Gomez, C.; Isaacs, A.; McCarroll, S.A.; Beekrnan, M.; Craen, A.J.M. de; Suchiman, H.E.D.; Hofman, A.; Oostra, B.; Uitterlinden, A.G.; Willemsen, G.; Plattee, M.; Veldink, J.H.; Berg, L.H. van den; Pitts, S.J.; Potluri, S.; Sundar, P.; Cox, D.R.; Sunyaev, S.R.; Dunnen, J.T. den; Stoneking, M.; Knijff, P. de; Kayser, M.; Li, Q.B.; Li, Y.R.; , Y.P. du; Chen, R.; Cao, H.; Li, N.; Cao, S.; Wang, J.; Bovenberg, J.A.; Peer, I.; Slagboom, P.E.; Duijn, C.M. van; Boomsma, D.I.; Ommen, G.J.B. van; Bakker, P.I.W. de; Swertz, M.A.; Wijmenga, C.; Genome Netherlands Consortium & LifeLines Cohort Study (2014), Whole-genome sequence variation, population structure and demographic history of the Dutch population, Nature Genetics 46(8): 818-825.
- Beenakker, K.G.M.; Koopman, J.J.E.; Bodegom, D. van; Kuningas, M.; Slagboom, P.E.; Meij, J.J.; Maier, A.B. & Westendorp, R.G.J. (2014), Variants of the IL-10 gene associate with muscle strength in elderly from rural Africa: a candidate gene study, Aging Cell 13(5): 862-868.
- Boomsma, D.I.; Wijmenga, C.; Slagboom, E.P.; Swertz, M.A.; Karssen, L.C.; Abdellaoui, A.; Ye, K.; Guryev, V.; Vermaat, M.; Dijk, F. van; Francioli, L.C.; Hottenga, J.J.; Laros, J.F.J.; Li, Q.B.; Li, Y.R.; Cao, H.Z.; Chen, R.Y.; , Y.P. du; Li, N.; Cao, S.J.; Setten, J. van; Menelaou, A.; Pulit, S.L.; Hehir-Kwa, J.Y.; Beekman, M.; Elbers, C.C.; Byelas, H.; Craen, A.J.M. de; Deelen, P.; Dijkstra, M.; Dunnen, J.T. den; Knijff, P. de; Houwing-Duistermaat, J.; Koval, V.; Estrada, K.; Hofman, A.; Kanterakis, A.; Enckevort, D. van; Mai, H.L.; Kattenberg, M.; Leeuwen, E.M. van; Neerincx, P.B.T.; Oostra, B.; Rivadeneira, F.; Suchiman, E.H.D.; Uitterlinden, A.G.; Willemsen, G.; Wolffenbuttel, B.H.; Wang, J.; Bakker, P.I.W. de; Ommen, G.J. van & Duijn, C.M. van (2014), The Genome of the Netherlands: design, and project goals, European Journal of Human Genetics 22(2): 221-227.
- Raule, N.; Sevini, F.; Li, S.T.; Barbieri, A.; Tallaro, F.; Lomartire, L.; Vianello, D.; Montesanto, A.; Moilanen, J.S.; Bezrukov, V.; Blanche, H.; Hervonen, A.; Christensen, K.; Deiana, L.; Gonos, E.S.; Kirkwood, T.B.L.; Kristensen, P.; Leon, A.; Pelicci, P.G.; Poulain, M.; Rea, I.M.; Remacle, J.; Robine, J.M.; Schreiber, S.; Sikora, E.; Slagboom, P.E.; Spazzafumo, L.; Stazi, M.A.; Toussaint, O.; Vaupel, J.W.; Rose, G.; Majamaa, K.; Perola, M.; Johnson, T.E.; Bolund, L.; Yang, H.M.; Passarino, G. & Franceschi, C. (2014), The co-occurrence of mtDNA mutations on different oxidative phosphorylation subunits, not detected by haplogroup analysis, affects human longevity and is population specific, Aging Cell 13(3): 401-407.
- Guigas, B.; Weenen, J.E.D. van; Leeuwen, N. van; Simonis-Bik, A.M.; Haeften, T.W. van; Nijpels, G.; Houwing-Duistermaat, J.J.; Beekman, M.; Deelen, J.; Havekes, L.M.; Penninx, B.W.J.H.; Vogelzangs, N.; Riet, E. van 't; Dehghan, A.; Hofman, A.; Witteman, J.C.; Uitterlinden, A.G.; Grarup, N.; Jorgensen, T.; Witte, D.R.; Lauritzen, T.; Hansen, T.; Pedersen, O.; Hottenga, J.; Romijn, J.A.; Diamant, M.; Kramer, M.H.H.; Heine, R.J.; Willemsen, G.; Dekker, J.M.; Eekhoff, E.M.; Pijl, H.; Geus, E.J. de; Slagboom, P.E. & Hart, L.M. 't (2014), Sex-specific effects of naturally occurring variants in the dopamine receptor D2 locus on insulin secretion and Type 2 diabetes susceptibility, Diabetic Medicine 31(8): 1001-1008.
- Styrkarsdottir, U.; Thorleifsson, G.; Helgadottir, H.T.; Bomer, N.; Metrustry, S.; Bierma-Zeinstra, S.; Strijbosch, A.M.; Evangelou, E.; Hart, D.; Beekman, M.; Jonasdottir, A.; Sigurdsson, A.; Eiriksson, F.F.; Thorsteinsdottir, M.; Frigge, M.L.; Kong, A.; Gudjonsson, S.A.; Magnusson, O.T.; Masson, G.; Hofman, A.; Arden, N.K.; Ingvarsson, T.; Lohmander, S.; Kloppenburg, M.; Rivadeneira, F.; Nelissen, R.G.H.H.; Spector, T.; Uitterlinden, A.; Slagboom, P.E.; Thorsteinsdottir, U.; Jonsdottir, I.; Valdes, A.M.; Meulenbelt, I.; Meurs, J. van; Jonsson, H.; Stefansson, K.; TREAT OA Consortium & arcOGEN Consortium (2014), Severe osteoarthritis of the hand associates with common variants within the ALDH1A2 gene and with rare variants at 1p31, Nature Genetics 46(5): 498-502.
- Goeij, M.C.M. de; Halbesma, N.; Dekker, F.W.; Wijsman, C.A.; Heemst, D. van; Maier, A.B.; Mooijaart, S.P.; Slagboom, P.E.; Westendorp, R.G.J. & Craen, A.J.M. de (2014), Renal function in familial longevity: the Leiden Longevity Study, Experimental Gerontology 51: 65-70.
- Almouzni, G.; Altucci, L.; Amati, B.; Ashley, N.; Baulcombe, D.; Beaujean, N.; Bock, C.; Bongcam-Rudloff, E.; Bousquet, J.; Braun, S.; Bressac-de Paillerets, B.; Bussemakers, M.; Clarke, L.; Conesa, A.; Estivill, X.; Fazeli, A.; Grgurevic, N.; Gut, I.; Heijmans, B.T.; Hermouet, S.; Houwing-Duistermaat, J.; Iacobucci, I.; Ilas, J.; Kandimalla, R.; Krauss-Etschmann, S.; Lasko, P.; Lehmann, S.; Lindroth, A.; Majdic, G.; Marcotte, E.; Martinelli, G.; Martinet, N.; Meyer, E.; Miceli, C.; Mills, K.; Moreno-Villanueva, M.; Morvan, G.; Nickel, D.; Niesler, B.; Nowacki, M.; Nowak, J.; Ossowski, S.; Pelizzola, M.; Pochet, R.; Potocnik, U.; Radwanska, M.; Raes, J.; Rattray, M.; Robinson, M.D.; Roelen, B.; Sauer, S.; Schinzer, D.; Slagboom, E.; Spector, T.; Stunnenberg, H.G.; Tiligada, E.; Torres-Padilla, M.E.; Tsonaka, R.; Soom, A. van; Vidakovic, M. & Widschwendter, M. (2014), Relationship between genome and epigenome - challenges and requirements for future research, BMC Genomics 15.
- Postmus, I.; Trompet, S.; Deshmukh, H.A.; Barnes, M.R.; Li, X.H.; Warren, H.R.; Chasman, D.I.; Zhou, K.X.; Arsenault, B.J.; Donnelly, L.A.; Wiggins, K.L.; Avery, C.L.; Griffin, P.; Feng, Q.P.; Taylor, K.D.; Li, G.; Evans, D.S.; Smith, A.V.; Keyser, C.E. de; Johnson, A.D.; Craen, A.J.M. de; Stott, D.J.; Buckley, B.M.; Ford, I.; Westendorp, R.G.J.; Slagboom, P.E.; Sattar, N.; Munroe, P.B.; Sever, P.; Poulter, N.; Stanton, A.; Shields, D.C.; O'Brien, E.; Shaw-Hawkins, S.; Chen, Y.D.I.; Nickerson, D.A.; Smith, J.D.; Dube, M.P.; Boekholdt, S.M.; Hovingh, G.K.; Kastelein, J.J.P.; McKeigue, P.M.; Betteridge, J.; Neil, A.; Durrington, P.N.; Doney, A.; Carr, F.; Morris, A.; McCarthy, M.I.; Groop, L.; Ahlqvist, E.; Bis, J.C.; Rice, K.; Smith, N.L.; Lumley, T.; Whitsel, E.A.; Sturmer, T.; Boerwinkle, E.; Ngwa, J.S.; O'Donnell, C.J.; Vasan, R.S.; Wei, W.Q.; Wilke, R.A.; Liu, C.T.; Sun, F.G.; Guo, X.Q.; Heckbert, S.R.; Post, W.; Sotoodehnia, N.; Arnold, A.M.; Stafford, J.M.; Ding, J.Z.; Herrington, D.M.; Kritchevsky, S.B.; Eiriksdottir, G.; Launer, L.J.; Harris, T.B.; Chu, A.Y.; Giulianini, F.; MacFadyen, J.G.; Barratt, B.J.; Nyberg, F.; Stricker, B.H.; Uitterlinden, A.G.; Hofman, A.; Rivadeneira, F.; Emilsson, V.; Franco, O.H.; Ridker, P.M.; Gudnason, V.; Liu, Y.M.; Denny, J.C.; Ballantyne, C.M.; Rotter, J.I.; Cupples, L.A.; Psaty, B.M.; Palmer, C.N.A.; Tardif, J.C.; Colhoun, H.M.; Hitman, G.; Krauss, R.M.; Jukema, J.W.; Caulfield, M.J. & Welcome Trust Case Control Consort (2014), Pharmacogenetic meta-analysis of genome-wide association studies of LDL cholesterol response to statins, Nature Communications 5.
- Baumert, J.; Huang, J.; McKnight, B.; Sabater-Lleal, M.; Steri, M.; Chu, A.Y.; Trompet, S.; Lopez, L.M.; Fornage, M.; Teumer, A.; Tang, W.H.; Rudnicka, A.R.; Malarstig, A.; Hottenga, J.J.; Kavousi, M.; Lahti, J.; Tanaka, T.; Hayward, C.; Huffman, J.E.; Morange, P.E.; Rose, L.M.; Basu, S.; Rumley, A.; Stott, D.J.; Buckley, B.M.; Craen, A.J.M. de; Sanna, S.; Masala, M.; Biffar, R.; Homuth, G.; Silveira, A.; Sennblad, B.; Goel, A.; Watkins, H.; Muller-Nurasyid, M.; Ruckerl, R.; Taylor, K.; Chen, M.H.; Geus, E.J.C. de; Hofman, A.; Witteman, J.C.M.; Maat, M.P.M. de; Palotie, A.; Davies, G.; Siscovick, D.S.; Kolcic, I.; Wild, S.H.; Song, J.; McArdle, W.L.; Ford, I.; Sattar, N.; Schlessinger, D.; Grotevendt, A.; Franzosi, M.G.; Illig, T.; Waldenberger, M.; Lumley, T.; Tofler, G.H.; Willemsen, G.; Uitterlinden, A.G.; Rivadeneira, F.; Raikkonen, K.; Chasman, D.I.; Folsom, A.R.; Lowe, G.D.; Westendorp, R.G.J.; Slagboom, P.E.; Cucca, F.; Wallaschofski, H.; Strawbridge, R.J.; Seedorf, U.; Koenig, W.; Bis, J.C.; Mukamal, K.J.; Dongen, J. van; Widen, E.; Franco, O.H.; Starr, J.M.; Liu, K.; Ferrucci, L.; Polasek, O.; Wilson, J.F.; Oudot-Mellakh, T.; Campbell, H.; Navarro, P.; Bandinelli, S.; Eriksson, J.; Boomsma, D.I.; Dehghan, A.; Clarke, R.; Hamsten, A.; Boerwinkle, E.; Jukema, J.W.; Naitza, S.; Ridker, P.M.; Volzke, H.; Deary, I.J.; Reiner, A.P.; Tregouet, D.A.; O'Donnell, C.J.; Strachan, D.P.; Peters, A. & Smith, N.L. (2014), No Evidence for Genome-Wide Interactions on Plasma Fibrinogen by Smoking, Alcohol Consumption and Body Mass Index: Results from Meta-Analyses of 80,607 Subjects, PLoS ONE 9(12).
- Thung, D.T.; Ligt, J. de; Vissers, L.E.M.; Steehouwer, M.; Kroon, M.; Vries, P. de; Slagboom, E.P.; Ye, K.; Veltman, J.A. & Hehir-Kwa, J.Y. (2014), Mobster: accurate detection of mobile element insertions in next generation sequencing data, Genome Biology 15(10).
- Sala, M.; Roos, A. de; Berg, A. van den; Altmann-Schneider, I.; Slagboom, P.E.; Westendorp, R.G.; Buchem, M.A. van; Craen, A.J.M. de & Grond, J. van der (2014), Microstructural Brain Tissue Damage in Metabolic Syndrome, Diabetes Care 37(2): 493-500.
- Leeuwen, N. van; Beekman, M.; Deelen, J.; Akker, E.B. van den; Craen, A.J.M. de; Slagboom, P.E. & Hart, L.M. 't (2014), Low mitochondrial DNA content associates with familial longevity: the Leiden Longevity Study, AGE 36(3): 1463-1470.
- Kroft, L.J.M.; Bijl, N. van der; Grond, J. van der; Altmann-Schneider, I.; Slagboom, P.E.; Westendorp, R.G.J.; Roos, A. de & Craen, A.J.M. de (2014), Low computed tomography coronary artery calcium scores in familial longevity: the Leiden Longevity Study, AGE 36(4).
- Derhovanessian, E.; Maier, A.B.; Hahnel, K.; McElhaney, J.E.; Slagboom, E.P. & Pawelec, G. (2014), Latent Infection with Cytomegalovirus Is Associated with Poor Memory CD4 Responses to Influenza A Core Proteins in the Elderly, Journal of Immunology 193(7): 3624-3631.
- Valdes, A.M.; Meulenbelt, I.; Chassaing, E.; Arden, N.K.; Bierma-Zeinstra, S.; Harat, D.; Hofman, A.; Karsdal, M.; Kloppenburg, M.; Kroon, H.M.; Slagboom, E.P.; Spector, T.D.; Uitterlinden, A.G.; Meurs, J.B. van & Bay-Jensen, A.C. (2014), Large scale meta-analysis of urinary C-terminal telopeptide, serum cartilage oligomeric protein and matrix metalloprotease degraded type II collagen and their role in prevalence, incidence and progression of osteoarthritis, Osteoarthritis and Cartilage 22(5): 683-689.
- Postmus, I.; Johnson, P.C.D.; Trompet, S.; Craen, A.J.M. de; Slagboom, P.E.; Devlin, J.J.; Shiffman, D.; Sacks, F.M.; Kearney, P.M.; Stott, D.J.; Buckley, B.M.; Sattar, N.; Ford, I.; Westendorp, R.G.J. & Jukema, J.W. (2014), In search for genetic determinants of clinically meaningful differential cardiovascular event reduction by pravastatin in the PHArmacogenetic study of Statins in the Elderly at risk (PHASE)/PROSPER study.
- Huang, J.; Huffman, J.E.; Yamkauchi, M.; Trompet, S.; Asselbergs, F.W.; Sabater-Lleal, M.; Tregouet, D.A.; Chen, W.M.; Smith, N.L.; Kleber, M.E.; Shin, S.Y.; Becker, D.M.; Tang, W.H.; Dehghan, A.; Johnson, A.D.; Truong, V.; Folkersen, L.; Yang, Q.; Oudot-Mellkah, T.; Buckley, B.M.; Moore, J.H.; Williams, F.M.K.; Campbell, H.; Silbernagel, G.; Vitart, V.; Rudan, I.; Tofler, G.H.; Navis, G.J.; DeStefano, A.; Wright, A.F.; Chen, M.H.; Craen, A.J.M. de; Worrall, B.B.; Rudnicka, A.R.; Rumley, A.; Bookman, E.B.; Psaty, B.M.; Chen, F.; Keene, K.L.; Franco, O.H.; Bohm, B.O.; Uitterlinden, A.G.; Carter, A.M.; Jukema, J.W.; Sattar, N.; Bis, J.C.; Ikram, M.A.; Sale, M.M.; McKnight, B.; Fornage, M.; Ford, I.; Taylor, K.; Slagboom, P.E.; McArdle, W.L.; Hsu, F.C.; Franco-Cereceda, A.; Goodall, A.H.; Yanek, L.R.; Furie, K.L.; Cushman, M.; Hofman, A.; Witteman, J.C.M.; Folsom, A.R.; Basu, S.; Matijevic, N.; Gilst, W.H. van; Wilson, J.F.; Westendorp, R.G.J.; Kathiresan, S.; Reilly, M.P.; Tracy, R.P.; Polasek, O.; Winkelmann, B.R.; Grant, P.J.; Hillege, H.L.; Cambien, F.; Stott, D.J.; Lowe, G.D.; Spector, T.D.; Meigs, J.B.; Marz, W.; Eriksson, P.; Becker, L.C.; Morange, P.E.; Soranzo, N.; Williams, S.M.; Hayward, C.; Harst, P. van der; Hamsten, A.; Lowenstein, C.J.; Strachan, D.P.; O'Donnell, C.J. & CHARGE Consortium Hemostatic (2014), Genome-Wide Association Study for Circulating Tissue Plasminogen Activator Levels and Functional Follow-Up Implicates Endothelial STXBP5 and STX2, Arteriosclerosis, Thrombosis, and Vascular Biology 34(5): 1093-1101.
- Albers, H.M.; Reinards, T.H.C.M.; Brinkman, D.M.C.; Kamphuis, S.S.M.; Rossum, M.A.J. van; Hoppenreijs, E.P.A.H.; Girschick, H.J.; Wouters, C.; Saurenmann, R.K.; Bakker, E.; Verduijn, W.; Slagboom, P.; Huizinga, T.W.J.; Toes, R.E.M.; Houwing-Duistermaat, J.J.; Cate, R. ten & Schilham, M.W. (2014), Genetic variation in VTCN1 (B7-H4) is associated with course of disease in juvenile idiopathic arthritis, Annals of the Rheumatic Diseases 73(6): 1198-1201.
- Avery, C.L.; Sitlani, C.M.; Arking, D.E.; Arnett, D.K.; Bis, J.C.; Boerwinkle, E.; Buckley, B.M.; Chen, Y.D.I.; Craen, A.J.M. de; Eijgelsheim, M.; Enquobahrie, D.; Evans, D.S.; Ford, I.; Garcia, M.E.; Gudnason, V.; Harris, T.B.; Heckbert, S.R.; Hochner, H.; Hofman, A.; Hsueh, W.C.; Isaacs, A.; Jukema, J.W.; Knekt, P.; Kors, J.A.; Krijthe, B.P.; Kristiansson, K.; Laaksonen, M.; Liu, Y.; Li, X.; MacFarlane, P.W.; Newton-Cheh, C.; Nieminen, M.S.; Oostra, B.A.; Peloso, G.M.; Porthan, K.; Rice, K.; Rivadeneira, F.F.; Rotter, J.I.; Salomaa, V.; Sattar, N.; Siscovick, D.S.; Slagboom, P.E.; Smith, A.V.; Sotoodehnia, N.; Stott, D.J.; Stricker, B.H.; Sturmer, T.; Trompet, S.; Uitterlinden, A.G.; Duijn, C. van; Westendorp, R.G.J.; Witteman, J.C.; Whitsel, E.A. & Psaty, B.M. (2014), Drug-gene interactions and the search for missing heritability: a cross-sectional pharmacogenomics study of the QT interval, Pharmacogenomics Journal 14(1): 6-13.
- Sala, M.; Kroft, L.J.M.; Roell, B.; Grond, J. van der; Slagboom, P.E.; Mooijaart, S.P.; Roos, A. de & Heemst, D. van (2014), Association of Liver Enzymes and Computed Tomography Markers of Liver Steatosis with Familial Longevity, PLoS ONE 9(3).
- Oei, L.; Hsu, Y.H.; Styrkarsdottir, U.; Eussen, B.H.; Klein, A. de; Peters, M.J.; Halldorsson, B.; Liu, C.T.; Alonso, N.; Kaptoge, S.K.; Thorleifsson, G.; Hallmans, G.; Hocking, L.J.; Husted, L.B.; Jameson, K.A.; Kruk, M.; Lewis, J.R.; Patel, M.S.; Scollen, S.; Svensson, O.; Trompet, S.; Schoor, N.M. van; Zhu, K.; Buckley, B.M.; Cooper, C.; Ford, I.; Goltzman, D.; Gonzalez-Macias, J.; Langdahl, B.L.; Leslie, W.D.; Lips, P.; Lorenc, R.S.; Olmos, J.M.; Pettersson-Kymmer, U.; Reid, D.M.; Riancho, J.A.; Slagboom, P.E.; Garcia-Ibarbia, C.; Ingvarsson, T.; Johannsdottir, H.; Luben, R.; Medina-Gomez, C.; Arp, P.; Nandakumar, K.; Palsson, S.T.; Sigurdsson, G.; Meurs, J.B.J. van; Zhou, Y.H.; Hofman, A.; Jukema, J.W.; Pols, H.A.P.; Prince, R.L.; Cupples, L.A.; Marshall, C.R.; Pinto, D.; Sato, D.; Scherer, S.W.; Reeve, J.; Thorsteinsdottir, U.; Karasik, D.; Richards, J.B.; Stefansson, K.; Uitterlinden, A.G.; Ralston, S.H.; Ioannidis, J.P.A.; Kiel, D.P.; Rivadeneira, F. & Estrada, K. (2014), A genome-wide copy number association study of osteoporotic fractures points to the 6p25.1 locus, Journal of Medical Genetics 51(2): 122-131.
- Broer, L.; Raschenberger, J.; Deelen, J.; Mangino, M.; Codd, V.; Pietilainen, K.H.; Albrecht, E.; Amin, N.; Beekman, M.; Craen, A.J.M. de; Gieger, C.; Haun, M.; Henneman, P.; Herder, C.; Hovatta, I.; Laser, A.; Kedenko, L.; Koenig, W.; Kollerits, B.; Moilanen, E.; Oostra, B.A.; Paulweber, B.; Quaye, L.; Rissanen, A.; Roden, M.; Surakka, I.; Valdes, A.M.; Vuolteenaho, K.; Thorand, B.; Dijk, K.W. van; Kaprio, J.; Spector, T.D.; Slagboom, P.E.; Samani, N.J.; Kronenberg, F.; Duijn, C.M. van & Ladwig, K.H. (2014), Association of adiponectin and leptin with relative telomere length in seven independent cohorts including 11,448 participants, European Journal of Epidemiology 29(9): 629-638.
- Dongen, J. van; Ehli, E.A.; Slieker, R.C.; Bartels, M.; Weber, Z.M.; Davies, G.E.; Slagboom, P.E.; Heijmans, B.T. & Boomsma, D.I. (2014), Epigenetic Variation in Monozygotic Twins: A Genome-Wide Analysis of DNA Methylation in Buccal Cells, Genes 5(2): 347-365.
- Claessen, K.M.J.A.; Kloppenburg, M.; Kroon, H.M.; Bijsterbosch, J.; Pereira, A.M.; Romijn, J.A.; Straaten, T. van der; Nelissen, R.G.H.H.; Hofman, A.; Uitterlinden, A.G.; Duijnisveld, B.J.; Lakenberg, N.; Beekman, M.; Meurs, J.B. van; Slagboom, P.E.; Biermasz, N.R. & Meulenbelt, I. (2014), Relationship between the functional exon 3 deleted growth hormone receptor polymorphism and symptomatic osteoarthritis in women, Annals of the Rheumatic Diseases 73(2): 433-436.
- Slof-Op't Landt, M.C.T.; DeRijk, R.H.; Son, G.E. van; Suchiman, H.E.D.; Meulenbelt, I.; Slagboom, P.E. & Furth, E.F. van (2014), A Common Mineralocorticoid Receptor Polymorphism (I180V) Interacts with Life Events in Relation to Perfectionism in Eating Disorders: A Pilot Study, European Eating Disorders Review 22(6): 423-429.
- Tobi, E.W.; Goeman, J.J.; Monajemi, R.; Gu, H.C.; Putter, H.; Zhang, Y.J.; Slieker, R.C.; Stok, A.P.; Thijssen, P.E.; Muller, F.; Zwet, E.W. van; Bock, C.; Meissner, A.; Lumey, L.H.; Slagboom, P.E. & Heijmans, B.T. (2014), DNA methylation signatures link prenatal famine exposure to growth and metabolism, Nature Communications 5.
- Iterson, M. van; Tobi, E.W.; Slieker, R.C.; Hollander, W. den; Luijk, R.; Slagboom, P.E. & Heijmans, B.T. (2014), MethylAid: visual and interactive quality control of large Illumina 450k datasets, Bioinformatics 30(23): 3435-3437.
- Evangelou, E.; Kerkhof, H.J.; Styrkarsdottir, U.; Ntzani, E.E.; Bos, S.D.; Esko, T.; Evans, D.S.; Metrustry, S.; Panoutsopoulou, K.; Ramos, Y.F.M.; Thorleifsson, G.; Tsilidis, K.K.; Arden, N.; Aslam, N.; Bellamy, N.; Birrell, F.; Blanco, F.J.; Carr, A.; Chapman, K.; Day-Williams, A.G.; Deloukas, P.; Doherty, M.; Engstrom, G.; Helgadottir, H.T.; Hofman, A.; Ingvarsson, T.; Jonsson, H.; Keis, A.; Keurentjes, J.C.; Kloppenburg, M.; Lind, P.A.; McCaskie, A.; Martin, N.G.; Milani, L.; Montgomery, G.W.; Nelissen, R.G.H.H.; Nevitt, M.C.; Nilsson, P.M.; Ollier, W.E.R.; Parimi, N.; Rai, A.; Ralston, S.H.; Reed, M.R.; Riancho, J.A.; Rivadeneira, F.; Rodriguez-Fontenla, C.; Southam, L.; Thorsteinsdottir, U.; Tsezou, A.; AWallis, G.; Wilkinson, J.M.; Gonzalez, A.; Lane, N.E.; Lohmander, L.S.; Loughlin, J.; Metspalu, A.; Uitterlinden, A.G.; Jonsdottir, I.; Stefansson, K.; Slagboom, P.E.; Zeggini, E.; Meulenbelt, I.; Ioannidis, J.P.A.; Spector, T.D.; Meurs, J.B.J. van; Valdes, A.M. & arcOGEN Consortium (2014), A meta-analysis of genome-wide association studies identifies novel variants associated with osteoarthritis of the hip, Annals of the Rheumatic Diseases 73(12): 2130-2136.
- Vroege, D.P.; Wijsman, C.A.; Broekhuizen, K.; Craen, A.J.M. de; Heemst, D. van; Ouderaa, F.J.G. van der; Mechelen, W. van; Slagboom, P.E.; Catt, M.; Westendorp, R.G.J.; Verhagen, E.A.L.M. & Mooijaart, S.P. (2014), Dose-Response Effects of a Web-Based Physical Activity Program on Body Composition and Metabolic Health in Inactive Older Adults: Additional Analyses of a Randomized Controlled Trial.
- Wood, A.R.; Esko, T.; Yang, J.; Vedantam, S.; Pers, T.H.; Gustafsson, S.; Chun, A.Y.; Estrada, K.; Luan, J.; Kutalik, Z.; Amin, N.; Buchkovich, M.L.; Croteau-Chonka, D.C.; Day, F.R.; Duan, Y.; Fall, T.; Fehrmann, R.; Ferreira, T.; Jackson, A.U.; Karjalainen, J.; , K.S. lo; Locke, A.E.; Magi, R.; Mihailov, E.; Porcu, E.; Randall, J.C.; Scherag, A.; Vinkhuyzen, A.A.E.; Westra, H.J.; Winkler, T.W.; Workalemahu, T.; Zhao, J.H.; Absher, D.; Albrecht, E.; Anderson, D.; Baron, J.; Beekman, M.; Demirkan, A.; Ehret, G.B.; Feenstra, B.; Feitosa, M.F.; Fischer, K.; Fraser, R.M.; Goel, A.; Gong, J.; Justice, A.E.; Kanoni, S.; Kleber, M.E.; Kristiansson, K.; Lim, U.; Lotay, V.; Lui, J.C.; Mangino, M.; Leach, I.M.; Medina-Gomez, C.; Nalls, M.A.; Nyholt, D.R.; Palmer, C.D.; Pasko, D.; Pechlivanis, S.; Prokopenko, I.; Ried, J.S.; Ripke, S.; Shungin, D.; Stancakova, A.; Strawbridge, R.J.; Sung, Y.J.; Tanaka, T.; Teumer, A.; Trompet, S.; Laan, S.W. van der; Setten, J. van; Vliet-Ostaptchouk, J.V. van; Wang, Z.M.; Yengo, L.; Zhang, W.H.; Afzal, U.; Arnlov, J.; Arscott, G.M.; Bandinelli, S.; Barrett, A.; Bellis, C.; Bennett, A.J.; Berne, C.; Bluher, M.; Bolton, J.L.; Bottcher, Y.; Boyd, H.A.; Bruinenberg, M.; Buckley, B.M.; Buyske, S.; Caspersen, I.H.; Chines, P.S.; Clarke, R.; Claudi-Boehm, S.; Cooper, M.; Daw, E.W.; Jong, P.A. de; Deelen, J.; Delgado, G.; Denny, J.C.; Dhonukshe-Rutten, R.; Dimitriou, M.; Doney, A.S.F.; Dorr, M.; Eklund, N.; Eury, E.; Folkersen, L.; Garcia, M.E.; Geller, F.; Giedraitis, V.; Go, A.S.; Grallert, H.; Grammer, T.B.; Grassler, J.; Gronberg, H.; Groot, L.C.P.G.M. de; Groves, C.J.; Haessler, J.; Hall, P.; Haller, T.; Hallmans, G.; Hannemann, A.; Hartman, C.A.; Hassinen, M.; Hayward, C.; Heard-Costa, N.L.; Helmer, Q.; Hemani, G.; Henders, A.K.; Hillege, H.L.; Hlatky, M.A.; Hoffmann, W.; Hoffmann, P.; Holmen, O.; Houwing-Duistermaat, J.J.; Illig, T.; Isaacs, A.; James, A.L.; Jeff, J.; Johansen, B.; Johansson, A.; Jolley, J.; Juliusdottir, T.; Junttila, J.; Kho, A.N.; Kinnunen, L.; Klopp, N.; Kocher, T.; Kratzer, W.; Lichtner, P.; Lind, L.; Lindstrom, J.; Lobbens, S.; Lorentzon, M.; Lu, Y.C.; Lyssenko, V.; Magnusson, P.K.E.; Mahajan, A.; Maillard, M.; McArdle, W.L.; McKenzie, C.A.; McLachlan, S.; McLaren, P.J.; Menni, C.; Merger, S.; Milani, L.; Moayyeri, A.; Monda, K.L.; Morken, M.A.; Muller, G.; Muller-Nurasyid, M.; Musk, A.W.; Narisu, N.; Nauck, M.; Nolte, I.M.; Nothen, M.M.; Oozageer, L.; Pilz, S.; Rayner, N.W.; Renstrom, F.; Robertson, N.R.; Rose, L.M.; Roussel, R.; Sanna, S.; Scharnagl, H.; Scholtens, S.; Schumacher, F.R.; Schunkert, H.; Scott, R.A.; Sehmi, J.; Seufferlein, T.; Shin, J.X.; Silventoinen, K.; Smit, J.H.; Smith, A.V.; Smolonska, J.; Stanton, A.V.; Stirrups, K.; Stott, D.J.; Stringham, H.M.; Sundstrom, J.; Swertz, M.A.; Syvanen, A.C.; Tayo, B.O.; Thorleifsson, G.; Tyrer, J.P.; Dijk, S. van; Schoor, N.M. van; Velde, N. van der; Heemst, D. van; Oort, F.V.A. van; Vermeulen, S.H.; Verweij, N.; Vonk, J.M.; Waite, L.L.; Waldenberger, M.; Wennauer, R.; Wilkens, L.R.; Willenborg, C.; Wilsgaard, T.; Wojczynski, M.K.; Wong, A.; Wright, A.F.; Zhang, Q.Y.; Arveiler, D.; Bakker, S.J.L.; Beilby, J.; Bergman, R.N.; Bergmann, S.; Biffar, R.; Blangero, J.; Boomsma, D.I.; Bornstein, S.R.; Bovet, P.; Brambilla, P.; Brown, M.J.; Campbell, H.; Caulfield, M.J.; Chakravarti, A.; Collins, R.; Collins, F.S.; Crawford, D.C.; Cupples, L.A.; Danesh, J.; Faire, U. de; Ruijter, H.M. den; Erbel, R.; Erdmann, J.; Eriksson, J.G.; Farrall, M.; Ferrannini, E.; Ferrieres, J.; Ford, I.; Forouhi, N.G.; Forrester, T.; Gansevoort, R.T.; Gejman, P.V.; Gieger, C.; Golay, A.; Gottesman, O.; Gudnason, V.; Gyllensten, U.; Haas, D.W.; Hall, A.S.; Harris, T.B.; Hattersley, A.T.; Heath, A.C.; Hengstenberg, C.; Hicks, A.A.; Hindorff, L.A.; Hingorani, A.D.; Hofman, A.; Hovingh, G.K.; Humphries, S.E.; Hunt, S.C.; Hypponen, E.; Jacobs, K.B.; Jarvelin, M.R.; Jousilahti, P.; Jula, A.M.; Kaprio, J. & Kastelei (2014), Defining the role of common variation in the genomic and biological architecture of adult human height, Nature Genetics 46(11): 1173-1186.
- Hafkemeijer, A.; Altmann-Schneider, I.; Craen, A.J.M. de; Slagboom, P.E.; Grond, J. van der & Rombouts, S.A.R.B. (2014), Associations between age and gray matter volume in anatomical brain networks in middle-aged to older adults, Aging Cell 13(6): 1068-1074.
- Boraska, V.; Franklin, C.S.; Floyd, J.A.B.; Thornton, L.M.; Huckins, L.M.; Southam, L.; Rayner, N.W.; Tachmazidou, I.; Klump, K.L.; Treasure, J.; Lewis, C.M.; Schmidt, U.; Tozzi, F.; Kiezebrink, K.; Hebebrand, J.; Gorwood, P.; Adan, R.A.H.; Kas, M.J.H.; Favaro, A.; Santonastaso, P.; Fernandez-Aranda, F.; Gratacos, M.; Rybakowski, F.; Dmitrzak-Weglarz, M.; Kaprio, J.; Keski-Rahkonen, A.; Raevuori, A.; Furth, E.F. van; Landt, M.C.T.S.O. 't; Hudson, J.I.; Reichborn-Kjennerud, T.; Knudsen, G.P.S.; Monteleone, P.; Kaplan, A.S.; Karwautz, A.; Hakonarson, H.; Berrettini, W.H.; Guo, Y.; Li, D.; Schork, N.J.; Komaki, G.; Ando, T.; Inoko, H.; Esko, T.; Fischer, K.; Mannik, K.; Metspalu, A.; Baker, J.H.; Cone, R.D.; Dackor, J.; DeSocio, J.E.; Hilliard, C.E.; O'Toole, J.K.; Pantel, J.; Szatkiewicz, J.P.; Taico, C.; Zerwas, S.; Trace, S.E.; Davis, O.S.P.; Helder, S.; Buhren, K.; Burghardt, R.; Zwaan, M. de; Egberts, K.; Ehrlich, S.; Herpertz-Dahlmann, B.; Herzog, W.; Imgart, H.; Scherag, A.; Scherag, S.; Zipfel, S.; Boni, C.; Ramoz, N.; Versini, A.; Brandys, M.K.; Danner, U.N.; Kovel, C. de; Hendriks, J.; Koeleman, B.P.C.; Ophoff, R.A.; Strengman, E.; Elburg, A.A. van; Bruson, A.; Clementi, M.; Degortes, D.; Forzan, M.; Tenconi, E.; Docampo, E.; Escaramis, G.; Jimenez-Murcia, S.; Lissowska, J.; Rajewski, A.; Szeszenia-Dabrowska, N.; Slopien, A.; Hauser, J.; Karhunen, L.; Meulenbelt, I.; Slagboom, P.E.; Tortorella, A.; Maj, M.; Dedoussis, G.; Dikeos, D.; Gonidakis, F.; Tziouvas, K.; Tsitsika, A.; Papezova, H.; Slachtova, L.; Martaskova, D.; Kennedy, J.L.; Levitan, R.D.; Yilmaz, Z.; Huemer, J.; Koubek, D.; Merl, E.; Wagner, G.; Lichtenstein, P.; Breen, G.; Cohen-Woods, S.; Farmer, A.; McGuffin, P.; Cichon, S.; Giegling, I.; Herms, S.; Rujescu, D.; Schreiber, S.; Wichmann, H.E.; Dina, C.; Sladek, R.; Gambaro, G.; Soranzo, N.; Julia, A.; Marsal, S.; Rabionet, R.; Gaborieau, V.; Dick, D.M.; Palotie, A.; Ripatti, S.; Widen, E.; Andreassen, O.A.; Espeseth, T.; Lundervold, A.; Reinvang, I.; Steen, V.M.; Hellard, S. le; Mattingsdal, M.; Ntalla, I.; Bencko, V.; Foretova, L.; Janout, V.; Navratilova, M.; Gallinger, S.; Pinto, D.; Scherer, S.W.; Aschauer, H.; Carlberg, L.; Schosser, A.; Alfredsson, L.; Ding, B.; Klareskog, L.; Padyukov, L.; Courtet, P.; Guillaume, S.; Jaussent, I.; Finan, C.; Kalsi, G.; Roberts, M.; Logan, D.W.; Peltonen, L.; Ritchie, G.R.S.; Barrett, J.C.; Estivill, X.; Hinney, A.; Sullivan, P.F.; Collier, D.A.; Zeggini, E.; Bulik, C.M. & Wellcome Trust Case Control Conso (2014), A genome-wide association study of anorexia nervosa, Molecular Psychiatry 19(10): 1085-1094.
- Hollander, W. den; Ramos, Y.F.M.; Bos, S.D.; Bomer, N.; Breggen, R. van der; Lakenberg, N.; Dijcker, W.J. de; Duijnisveld, B.J.; Slagboom, P.E.; Nelissen, R.G.H.H. & Meulenbelt, I. (2014), Knee and hip articular cartilage have distinct epigenomic landscapes: implications for future cartilage regeneration approaches, Annals of the Rheumatic Diseases 73(12): 2208-2212.
- Deelen, J.; Beekman, M.; Capri, M.; Franceschi, C. & Slagboom, P.E. (2013), Identifying the genomic determinants of aging and longevity in human population studies: Progress and challenges, BioEssays 35(4): 386-396.
- Dall'Olio, F.; Vanhooren, V.; Chen, C.C.; Slagboom, P.E.; Wuhrer, M. & Franceschi, C. (2013), N-glycomic biomarkers of biological aging and longevity: A link with inflammaging, Ageing Research Reviews 12(2): 685-698.
- Willemsen, G.; Vink, J.M.; Abdellaoui, A.; Braber, A. den; Beek, J.H.D.A. van; Draisma, H.H.M.; Dongen, J. van; van't Ent, D.; Geels, L.M.; Lien, R. van; Ligthart, L.; Kattenberg, M.; Mbarek, H.; Moor, M.H.M. de; Neijts, M.; Pool, R.; Stroo, N.; Kluft, C.; Suchiman, H.E.D.; Slagboom, P.E.; Geus, E.J.C. de & Boomsma, D.I. (2013), The Adult Netherlands Twin Register: Twenty-Five Years of Survey and Biological Data Collection, Twin Research and Human Genetics 16(1): 271-281.
- Noordam, R.; Gunn, D.A.; Tomlin, C.C.; Maier, A.B.; Griffiths, T.; Catt, S.D.; Ogden, S.; Slagboom, P.E.; Westendorp, R.G.J.; Griffiths, C.E.M.; Heemst, D. van; Craen, A.J.M. de & Leiden Longevity Study Grp (2013), Serum insulin-like growth factor 1 and facial ageing: high levels associate with reduced skin wrinkling in a cross-sectional study.
- Postmus, I.; Trompet, S.; Craen, A.J.M. de; Buckley, B.M.; Ford, I.; Stott, D.J.; Sattar, N.; Slagboom, P.E.; Westendorp, R.G.J. & Jukema, J.W. (2013), PCSK9 SNP rs11591147 is associated with low cholesterol levels but not with cognitive performance or noncardiovascular clinical events in an elderly population., Journal of Lipid Research 54(2): 561-6.
- Verschuren, J.J.W.; Trompet, S.; Deelen, J.; Stott, D.J.; Sattar, N.; Buckley, B.M.; Ford, I.; Heijmans, B.T.; Guchelaar, H.J.; Houwing-Duistermaat, J.J.; Slagboom, P.E. & Jukema, J.W. (2013), Non-Homologous End-Joining Pathway Associated with Occurrence of Myocardial Infarction: Gene Set Analysis of Genome-Wide Association Study Data, PLoS ONE 8(2).
- Porcu, E.; Medici, M.; Pistis, G.; Volpato, C.B.; Wilson, S.G.; Cappola, A.R.; Bos, S.D.; Deelen, J.; Heijer, M. den; Freathy, R.M.; Lahti, J.; Liu, C.Y.; Lopez, L.M.; Nolte, I.M.; O'Connell, J.R.; Tanaka, T.; Trompet, S.; Arnold, A.; Bandinelli, S.; Beekman, M.; Bohringer, S.; Brown, S.J.; Buckley, B.M.; Camaschella, C.; Craen, A.J.M. de; Davies, G.; Visser, M.C.H. de; Ford, I.; Forsen, T.; Frayling, T.M.; Fugazzola, L.; Gogele, M.; Hattersley, A.T.; Hermus, A.R.; Hofman, A.; Houwing-Duistermaat, J.J.; Jensen, R.A.; Kajantie, E.; Kloppenburg, M.; Lim, E.M.; Masciullo, C.; Mariotti, S.; Minelli, C.; Mitchell, B.D.; Nagaraja, R.; Netea-Maier, R.T.; Palotie, A.; Persani, L.; Piras, M.G.; Psaty, B.M.; Raikkonen, K.; Richards, J.B.; Rivadeneira, F.; Sala, C.; Sabra, M.M.; Sattar, N.; Shields, B.M.; Soranzo, N.; Starr, J.M.; Stott, D.J.; Sweep, F.C.G.J.; Usala, G.; Klauw, M.M. van der; Heemst, D. van; Mullem, A. van; Vermeulen, S.H.; Visser, W.E.; Walsh, J.P.; Westendorp, R.G.J.; Widen, E.; Zhai, G.J.; Cucca, F.; Deary, I.J.; Eriksson, J.G.; Ferrucci, L.; Fox, C.S.; Jukema, J.W.; Kiemeney, L.A.; Pramstaller, P.P.; Schlessinger, D.; Shuldiner, A.R.; Slagboom, E.P.; Uitterlinden, A.G.; Vaidya, B.; Visser, T.J.; Wolffenbuttel, B.H.R.; Meulenbelt, I.; Rotter, J.I.; Spector, T.D.; Hicks, A.A.; Toniolo, D.; Sanna, S.; Peeters, R.P. & Naitza, S. (2013), A Meta-Analysis of Thyroid-Related Traits Reveals Novel Loci and Gender-Specific Differences in the Regulation of Thyroid Function, PLoS Genetics 9(2).
- Bijsterbosch, J.; Kloppenburg, M.; Reijnierse, M.; Rosendaal, F.R.; Huizinga, T.W.J.; Slagboom, P.E. & Meulenbelt, I. (2013), Association study of candidate genes for the progression of hand osteoarthritis, Osteoarthritis and Cartilage 21(4): 565-569.
- Peters, M.J.; Broer, L.; Willemen, H.L.D.M.; Eiriksdottir, G.; Hocking, L.J.; Holliday, K.L.; Horan, M.A.; Meulenbelt, I.; Neogi, T.; Popham, M.; Schmidt, C.O.; Soni, A.; Valdes, A.M.; Amin, N.; Dennison, E.M.; Eijkelkamp, N.; Harris, T.B.; Hart, D.J.; Hofman, A.; Huygen, F.J.P.M.; Jameson, K.A.; Jones, G.T.; Launer, L.J.; Kerkhof, H.J.M.; Kruijf, M. de; McBeth, J.; Kloppenburg, M.; Ollier, W.E.; Oostra, B.; Payton, A.; Rivadeneira, F.; Smith, B.H.; Smith, A.V.; Stolk, L.; Teumer, A.; Thomson, W.; Uitterlinden, A.G.; Wang, K.; Wingerden, S.H. van; Arden, N.K.; Cooper, C.; Felson, D.; Gudnason, V.; Macfarlane, G.J.; Pendleton, N.; Slagboom, P.E.; Spector, T.D.; Volzke, H.; Kavelaars, A.; Duijn, C.M. van; Williams, F.M.K. & Meurs, J.B.J. van (2013), Genome-wide association study meta-analysis of chronic widespread pain: evidence for involvement of the 5p15.2 region, Annals of the Rheumatic Diseases 72(3): 427-436.
- Verschuren, J.J.W.; Trompet, S.; Sampietro, M.L.; Heijmans, B.T.; Koch, W.; Kastrati, A.; Houwing-Duistermaat, J.J.; Slagboom, P.E.; Quax, P.H.A. & Jukema, J.W. (2013), Pathway Analysis Using Genome-Wide Association Study Data for Coronary Restenosis - A Potential Role for the PARVB Gene, PLoS ONE 8(8).
- Lauc, G.; Huffman, J.E.; Pucic, M.; Zgaga, L.; Adamczyk, B.; Muzinic, A.; Novokmet, M.; Polasek, O.; Gornik, O.; Kristic, J.; Keser, T.; Vitart, V.; Scheijen, B.; Uh, H.W.; Molokhia, M.; Patrick, A.L.; McKeigue, P.; Kolcic, I.; Lukic, I.K.; Swann, O.; Leeuwen, F.N. van; Ruhaak, L.R.; Houwing-Duistermaat, J.J.; Slagboom, P.E.; Beekman, M.; Craen, A.J.M. de; Deelder, A.M.; Zeng, Q.; Wang, W.; Hastie, N.D.; Gyllensten, U.; Wilson, J.F.; Wuhrer, M.; Wright, A.F.; Rudd, P.M.; Hayward, C.; Aulchenko, Y.; Campbell, H. & Rudan, I. (2013), Loci Associated with N-Glycosylation of Human Immunoglobulin G Show Pleiotropy with Autoimmune Diseases and Haematological Cancers, PLoS Genetics 9(1): -.
- Thijssen, P.E.; Tobi, E.W.; Balog, J.; Schouten, S.G.; Kremer, D.; Bouazzaoui, F. el; Henneman, P.; Putter, H.; Slagboom, P.E.; Heijmans, B.T. & Maarel, S.M. van der (2013), Chromatin remodeling of human subtelomeres and TERRA promoters upon cellular senescence Commonalities and differences between chromosomes, Epigenetics 8(5): 512-521.
- Kiezun, A.; Pulit, S.L.; Francioli, L.C.; Dijk, F. van; Swertz, M.; Boomsma, D.I.; Duijn, C.M. van; Slagboom, P.E.; Ommen, G.J.B. van; Wijmenga, C.; Bakker, P.I.W. de; Sunyaev, S.R. & Genome Netherlands Consortium (2013), Deleterious Alleles in the Human Genome Are on Average Younger Than Neutral Alleles of the Same Frequency, PLoS Genetics 9(2).
- Bomer, N.; Ramos, Y.F.; Bos, S.D.; Duijnisveld, B.J.; Slagboom, P.E.; Nelissen, R.G. & Meulenbelt, I. (2013), DIO2 FUNCTIONS VIA T3: AN IN VITRO MODEL FOR CHONDROGENESIS, Osteoarthritis and Cartilage 21: S280-S281.
- Codd, V.; Nelson, C.P.; Albrecht, E.; Mangino, M.; Deelen, J.; Buxton, J.L.; Hottenga, J.J.; Fischer, K.; Esko, T.; Surakka, I.; Broer, L.; Nyholt, D.R.; Leach, I.M.; Salo, P.; Hagg, S.; Matthews, M.K.; Palmen, J.; Norata, G.D.; O'Reilly, P.F.; Saleheen, D.; Amin, N.; Balmforth, A.J.; Beekman, M.; Boer, R.A. de; Bohringer, S.; Braund, P.S.; Burton, P.R.; Craen, A.J.M. de; Denniff, M.; Dong, Y.B.; Douroudis, K.; Dubinina, E.; Eriksson, J.G.; Garlaschelli, K.; Guo, D.H.; Hartikainen, A.L.; Henders, A.K.; Houwing-Duistermaat, J.J.; Kananen, L.; Karssen, L.C.; Kettunen, J.; Klopp, N.; Lagou, V.; Leeuwen, E.M. van; Madden, P.A.; Magi, R.; Magnusson, P.K.E.; Mannisto, S.; McCarthy, M.I.; Medland, S.E.; Mihailov, E.; Montgomery, G.W.; Oostra, B.; Palotie, A.; Peters, A.; Pollard, H.; Pouta, A.; Prokopenko, I.; Ripatti, S.; Salomaa, V.; Suchiman, H.E.D.; Valdes, A.M.; Verweij, N.; Vinuela, A.; Wang, X.L.; Wichmann, H.E.; Widen, E.; Willemsen, G.; Wright, M.J.; Xia, K.; Xiao, X.J.; Veldhuisen, D.J. van; Catapano, A.L.; Tobin, M.D.; Hall, A.S.; Blakemore, A.I.F.; Gilst, W.H. van; Zhu, H.D.; Erdmann, J.; Reilly, M.P.; Kathiresan, S.; Schunkert, H.; Talmud, P.J.; Pedersen, N.L.; Perola, M.; Ouwehand, W.; Kaprio, J.; Martin, N.G.; Duijn, C.M. van; Hovatta, I.; Gieger, C.; Metspalu, A.; Boomsma, D.I.; Jarvelin, M.R.; Slagboom, P.E.; Thompson, J.R.; Spector, T.D.; Harst, P. van der; Samani, N.J. & CARDIoGRAM Consortium (2013), Identification of seven loci affecting mean telomere length and their association with disease, Nature Genetics 45(4): 422-427.
- Passtoors, W.M.; Beekman, M.; Deelen, J.; Breggen, R. van der; Maier, A.B.; Guigas, B.; Derhovanessian, E.; Heemst, D. van; Craen, A.J.M. de; Gunn, D.A.; Pawelec, G. & Slagboom, P.E. (2013), Gene expression analysis of mTOR pathway: association with human longevity, Aging Cell 12(1): 24-31.
- Stijntjes, M.; Craen, A.J.M. de; Heemst, D. van; Meskers, C.G.M.; Buchem, M.A. van; Westendorp, R.G.J.; Slagboom, P.E. & Maier, A.B. (2013), Familial Longevity Is Marked by Better Cognitive Performance at Middle Age: The Leiden Longevity Study, PLoS ONE 8(3).
- Slof-Op't Landt, M.C.T.; Bartels, M.; Middeldorp, C.M.; Beijsterveldt, C.E.M.; Slagboom, P.E.; Boomsma, D.I.; Furth, E.F. van & Meulenbelt, I. (2013), Genetic Variation at the TPH2 Gene Influences Impulsivity in Addition to Eating Disorders, Behavior Genetics 43(1): 24-33.
- Ramos, Y.F.; Meurs, J.B. van; Valdes, A.M.; Metrustry, S.; Hart, D.; Arden, N.; Kloppenburg, M.; Lafeber, F.; Spil, E.W. van; Karsdal, M.; Bay-Jensen, A.; Spector, T.; Uitterlinden, A.; Slagboom, P.E. & Meulenbelt, I. (2013), META-ANALYSIS IDENTIFIES NOVEL GENES INFLUENCING LEVELS OF THE POTENTIAL OA BIOMARKERS SCOMP AND UCTX2, Osteoarthritis and Cartilage 21: S169-S169.
- Albrechtsen, A.; Grarup, N.; Li, Y.; Sparso, T.; Tian, G.; Cao, H.; Jiang, T.; Kim, S.Y.; Korneliussen, T.; Li, Q.; Nie, C.; Wu, R.; Skotte, L.; Morris, A.P.; Ladenvall, C.; Cauchi, S.; Stancakova, A.; Andersen, G.; Astrup, A.; Banasik, K.; Bennett, A.J.; Bolund, L.; Charpentier, G.; Chen, Y.; Dekker, J.M.; Doney, A.S.F.; Dorkhan, M.; Forsen, T.; Frayling, T.M.; Groves, C.J.; Gui, Y.; Hallmans, G.; Hattersley, A.T.; He, K.; Hitman, G.A.; Holmkvist, J.; Huang, S.; Jiang, H.; Jin, X.; Justesen, J.M.; Kristiansen, K.; Kuusisto, J.; Lajer, M.; Lantieri, O.; Li, W.; Liang, H.; Liao, Q.; Liu, X.; Ma, T.; Ma, X.; Manijak, M.P.; Marre, M.; Mokrosinski, J.; Morris, A.D.; Mu, B.; Nielsen, A.A.; Nijpels, G.; Nilsson, P.; Palmer, C.N.A.; Rayner, N.W.; Renstrom, F.; Ribel-Madsen, R.; Robertson, N.; Rolandsson, O.; Rossing, P.; Schwartz, T.W.; Slagboom, P.E.; Sterner, M.; Tang, M.; Tarnow, L.; Tuomi, T.; van't Riet, E.; Leeuwen, N. van; Varga, T.V.; Vestmar, M.A.; Walker, M.; Wang, B.; Wang, Y.; Wu, H.; Xi, F.; Yengo, L.; Yu, C.; Zhang, X.; Zhang, J.; Zhang, Q.; Zhang, W.; Zheng, H.; Zhou, Y.; Altshuler, D.; Hart, L.M. 't; Franks, P.W.; Balkau, B.; Froguel, P.; McCarthy, M.I.; Laakso, M.; Groop, L.; Christensen, C.; Brandslund, I.; Lauritzen, T.; Witte, D.R.; Linneberg, A.; Jorgensen, T.; Hansen, T.; Wang, J.; Nielsen, R.; Pedersen, O.; DESIR Study Grp & DIAGRAM Consortium (2013), Exome sequencing-driven discovery of coding polymorphisms associated with common metabolic phenotypes, Diabetologia 56(2): 298-310.
- Altmann-Schneider, I.; Craen, A.J.M. de; Veer, I.M.; Berg-Huysmans, A.A. van den; Slagboom, P.E.; Westendorp, R.G.J.; Buchem, M.A. van; Grond, J. van der & Leiden Longevity Study Grp (2013), Preserved White Matter Integrity Is a Marker of Familial Longevity, Annals of Neurology 74(6): 883-892.
- Bay-Jensen, A.C.; Slagboom, E.; Chen-An, P.; Alexandersen, P.; Qvist, P.; Christiansen, C.; Meulenbelt, I. & Karsdal, M.A. (2013), Role of hormones in cartilage and joint metabolism: understanding an unhealthy metabolic phenotype in osteoarthritis, Menopause 20(5): 578-586.
- Slieker, R.C.; Bos, S.D.; Goeman, J.J.; Bovee, J.V.M.G.; Talens, R.P.; Breggen, R. van der; Suchiman, H.E.D.; Lameijer, E.W.; Putter, H.; Akker, E.B. van den; Zhang, Y.J.; Jukema, J.W.; Slagboom, P.E.; Meulenbelt, I. & Heijmans, B.T. (2013), Identification and systematic annotation of tissue-specific differentially methylated regions using the Illumina 450k array, Epigenetics and Chromatin 6.
- Visser, M.C.H. de; Minkelen, R. van; Marion, V. van; Heijer, M. den; Eikenboom, J.; Vos, H.L.; Slagboom, P.E.; Houwing-Duistermaat, J.J.; Rosendaal, F.R. & Bertina, R.M. (2013), Genome-wide linkage scan in affected sibling pairs identifies novel susceptibility region for venous thromboembolism: Genetics In Familial Thrombosis study, Journal of Thrombosis and Haemostasis 11(8): 1474-1484.
- Obermann-Borst, S.A.; Eilers, P.H.C.; Tobi, E.W.; Jong, F.H. de; Slagboom, P.E.; Heijmans, B.T. & Steegers-Theunissen, R.P.M. (2013), Duration of breastfeeding and gender are associated with methylation of the LEPTIN gene in very young children, Pediatric Research 74(3): 344-349.
- Ye, K.; Beekman, M.; Lameijer, E.W.; Zhang, Y.J.; Moed, M.H.; Akker, E.B. van den; Deelen, J.; Houwing-Duistermaat, J.J.; Kremer, D.; Anvar, S.Y.; Laros, J.F.J.; Jones, D.; Raine, K.; Blackburne, B.; Potluri, S.; Long, Q.; Guryev, V.; Breggen, R. van der; Westendorp, R.G.J.; Hoen, P.A.C. 't; Dunnen, J. den; Ommen, G.J.B. van; Willemsen, G.; Pitts, S.J.; Cox, D.R.; Ning, Z.M.; Boomsma, D.I. & Slagboom, P.E. (2013), Aging as Accelerated Accumulation of Somatic Variants: Whole-Genome Sequencing of Centenarian and Middle-Aged Monozygotic Twin Pairs, Twin Research and Human Genetics 16(6): 1026-1032.
- Postmus, I.; Trompet, S.; Craen, A.J.M. de; Shiffman, D.; Devlin, J.J.; Ford, I.; Sattar, N.; Stott, D.J.; Slagboom, P.E.; Jukema, J.W. & PROSPER PHASE Study (2013), No genetic determinants of differential cardiovascular event reduction by pravastatin in the PROSPER/PHASE study, European Heart Journal 34: 17-17.
- Broer, L.; Codd, V.; Nyholt, D.R.; Deelen, J.; Mangino, M.; Willemsen, G.; Albrecht, E.; Amin, N.; Beekman, M.; Geus, E.J.C. de; Henders, A.; Nelson, C.P.; Steves, C.J.; Wright, M.J.; Craen, A.J.M. de; Isaacs, A.; Matthews, M.; Moayyeri, A.; Montgomery, G.W.; Oostra, B.A.; Vink, J.M.; Spector, T.D.; Slagboom, P.E.; Martin, N.G.; Samani, N.J.; Duijn, C.M. van & Boomsma, D.I. (2013), Meta-analysis of telomere length in 19 713 subjects reveals high heritability, stronger maternal inheritance and a paternal age effect, European Journal of Human Genetics 21(10): 1163-1168.
- Derhovanessian, E.; Maier, A.B.; Hahnel, K.; Zelba, H.; Craen, A.J.M. de; Roelofs, H.; Slagboom, E.P.; Westendorp, R.G.J. & Pawelec, G. (2013), Lower proportion of na < ve peripheral CD8+T cells and an unopposed pro-inflammatory response to human Cytomegalovirus proteins in vitro are associated with longer survival in very elderly people, AGE 35(4): 1387-1399.
- Draisma, H.H.M.; Beekman, M.; Pool, R.; Ommen, G.J.B. van; Vaarhorst, A.A.M.; Craen, A.J.M. de; Willemsen, G.; Slagboom, P.E. & Boomsma, D.I. (2013), Familial Resemblance for Serum Metabolite Concentrations, Twin Research and Human Genetics 16(5): 947-961.
- Wijsman, C.A.; Westendorp, R.G.J.; Verhagen, E.A.L.M.; Catt, M.; Slagboom, E.; Craen, A.J.M. de; Broekhuizen, K.; Mechelen, W. van; Heemst, D. van; Ouderaa, F. van der & Mooijaart, S.P. (2013), Effects of a Web-Based Intervention on Physical Activity and Metabolism in Older Adults: Randomized Controlled Trial, JMIR 15(11).
- Williams, F.M.K.; Bansal, A.T.; Meurs, J.B. van; Bell, J.T.; Meulenbelt, I.; Suri, P.; Rivadeneira, F.; Sambrook, P.N.; Hofman, A.; Bierma-Zeinstra, S.; Menni, C.; Kloppenburg, M.; Slagboom, P.E.; Hunter, D.J.; MacGregor, A.J.; Uitterlinden, A.G. & Spector, T.D. (2013), Novel genetic variants associated with lumbar disc degeneration in northern Europeans: a meta-analysis of 4600 subjects, Annals of the Rheumatic Diseases 72(7): 1141-1148.
- Bos, S.D.; Beekman, M.; Maier, A.B.; Karsdal, M.A.; Kwok, W.Y.; Bay-Jensen, A.C.; Kloppenburg, M.; Slagboom, P.E. & Meulenbelt, I. (2013), Metabolic health in families enriched for longevity is associated with low prevalence of hand osteoarthritis and influences OA biomarker profiles, Annals of the Rheumatic Diseases 72(10): 1669-1674.
- Brandys, M.K.; Kas, M.J.H.; Elburg, A.A. van; Ophoff, R.; Slof-Op't Landt, M.C.T.; Middeldorp, C.M.; Boomsma, D.I.; Furth, E.F. van; Slagboom, P.E. & Adan, R.A.H. (2013), The Val66Met polymorphism of the BDNF gene in anorexia nervosa: New data and a meta-analysis.
- Sanchez-Faddeev, H.; Pijpe, J.; Hulle, T. van der; Meij, H.J.; Gaag, K.J. van der; Slagboom, P.E.; Westendorp, R.G.J. & Knijff, P. de (2013), The influence of clan structure on the genetic variation in a single Ghanaian village, European Journal of Human Genetics 21(10): 1134-1139.
- Gonzalez-Covarrubias, V.; Beekman, M.; Uh, H.W.; Dane, A.; Troost, J.; Paliukhovich, I.; Kloet, F.M. van der; Houwing-Duistermaat, J.; Vreeken, R.J.; Hankemeier, T. & Slagboom, E.P. (2013), Lipidomics of familial longevity, Aging Cell 12(3): 426-434.
- Ramos, Y.F.; Meurs, J.B. van; Valdes, A.M.; Metrustry, S.; Hart, D.; Arden, N.; Kloppenburg, M.; Lafeber, F.; Spil, E.W. van; Karsdal, M.; Bay-Jensen, A.; Spector, T.; Uitterlinden, A.; Slagboom, P.E. & Meulenbelt, I. (2013), META-ANALYSIS IDENTIFIES NOVEL GENES INFLUENCING LEVELS OF THE POTENTIAL OA BIOMARKERS SCOMP AND UCTX2, Osteoarthritis and Cartilage 21: S169-S169.
- Lotz, M.; Martel-Pelletier, J.; Christiansen, C.; Brandi, M.L.; Bruyere, O.; Chapurlat, R.; Collette, J.; Cooper, C.; Giacovelli, G.; Kanis, J.A.; Karsdal, M.A.; Kraus, V.; Lems, W.F.; Meulenbelt, I.; Pelletier, J.P.; Raynauld, J.P.; Reiter-Niesert, S.; Rizzoli, R.; Sandell, L.J.; Spil, W.E. van & Reginster, J.Y. (2013), Value of biomarkers in osteoarthritis: current status and perspectives, Annals of the Rheumatic Diseases 72(11): 1756-1763.
- Ruhaak, L.R.; Koeleman, C.A.M.; Uh, H.W.; Stam, J.C.; Heemst, D. van; Maier, A.B.; Houwing-Duistermaat, J.J.; Hensbergen, P.J.; Slagboom, P.E.; Deelder, A.M. & Wuhrer, M. (2013), Targeted Biomarker Discovery by High Throughput Glycosylation Profiling of Human Plasma Alpha1-Antitrypsin and Immunoglobulin A, PLoS ONE 8(9).
- Hart, L.M. 't; Fritsche, A.; Nijpels, G.; Leeuwen, N. van; Donnelly, L.A.; Dekker, J.M.; Alssema, M.; Fadista, J.; Carlotti, F.; Gjesing, A.P.; Palmer, C.N.A.; Haeften, T.W. van; Herzberg-Schafer, S.A.; Simonis-Bik, A.M.C.; Houwing-Duistermaat, J.J.; Helmer, Q.; Deelen, J.; Guigas, B.; Hansen, T.; Machicao, F.; Willemsen, G.; Heine, R.J.; Kramer, M.H.H.; Holst, J.J.; Koning, E.J.P. de; Haring, H.U.; Pedersen, O.; Groop, L.; Geus, E.J.C. de; Slagboom, P.E.; Boomsma, D.I.; Eekhoff, E.M.W.; Pearson, E.R. & Diamant, M. (2013), The CTRB1/2 Locus Affects Diabetes Susceptibility and Treatment via the Incretin Pathway, Diabetes 62(9): 3275-3281.
- Streppel, M.T.; Vries, J.H.M. de; Meijboom, S.; Beekman, M.; Craen, A.J.M. de; Slagboom, P.E. & Feskens, E.J.M. (2013), Relative validity of the food frequency questionnaire used to assess dietary intake in the Leiden Longevity Study, Nutrition Journal 12.
- Beenakker, K.G.M.; Westendorp, R.G.J.; Craen, A.J.M. de; Slagboom, P.E.; Heemst, D. van & Maier, A.B. (2013), Pro-inflammatory capacity of classically activated monocytes relates positively to muscle mass and strength., Aging Cell 12(4): 682-9.
- Evangelou, E.; Valdes, A.M.; Castano-Betancourt, M.C.; Doherty, M.; Doherty, S.; Esko, T.; Ingvarsson, T.; Ioannidis, J.P.A.; Kloppenburg, M.; Metspalu, A.; Ntzani, E.E.; Panoutsopoulou, K.; Slagboom, P.E.; Southam, L.; Spector, T.D.; Styrkarsdottir, U.; Stefanson, K.; Uitterlinden, A.G.; Wheeler, M.; Zeggini, E.; Meulenbelt, I.; Meurs, J.B. van; ArcOGEN Consortium & TREAT-OA Consortium (2013), The DOT1L rs12982744 polymorphism is associated with osteoarthritis of the hip with genome- wide statistical significance in males, Annals of the Rheumatic Diseases 72(7): 1264-U202.
- Beekman, M.; Blanche, H.; Perola, M.; Hervonen, A.; Bezrukov, V.; Sikora, E.; Flachsbart, F.; Christiansen, L.; Craen, A.J.M. de; Kirkwood, T.B.L.; Rea, I.M.; Poulain, M.; Robine, J.M.; Valensin, S.; Stazi, M.A.; Passarino, G.; Deiana, L.; Gonos, E.S.; Paternoster, L.; Sorensen, T.I.A.; Tan, Q.H.; Helmer, Q.; Akker, E.B. van den; Deelen, J.; Martella, F.; Cordell, H.J.; Ayers, K.L.; Vaupel, J.W.; Tornwall, O.; Johnson, T.E.; Schreiber, S.; Lathrop, M.; Skytthe, A.; Westendorp, R.G.J.; Christensen, K.; Gampe, J.; Nebel, A.; Houwing-Duistermaat, J.J.; Slagboom, P.E.; Franceschi, C. & GEHA Consortium (2013), Genome-wide linkage analysis for human longevity: Genetics of Healthy Aging Study., Aging Cell.
- Gunn, D.A.; Craen, A.J.M. de; Dick, J.L.; Tomlin, C.C.; Heemst, D. van; Catt, S.D.; Griffiths, T.; Ogden, S.; Maier, A.B.; Murray, P.G.; Griffiths, C.E.M.; Slagboom, P.E. & Westendorp, R.G.J. (2013), Facial Appearance Reflects Human Familial Longevity and Cardiovascular Disease Risk in Healthy Individuals, Journals of Gerontology, Series A 68(2): 145-152.
- Altmann-Schneider, I.; Grond, J. van der; Slagboom, P.E.; Westendorp, R.G.J.; Maier, A.B.; Buchem, M.A. van & Craen, A.J.M. de (2013), Lower Susceptibility to Cerebral Small Vessel Disease in Human Familial Longevity The Leiden Longevity Study, Stroke 44(1): 9-14.
- Altmann-Schneider, I.; Grond, J. van der; Slagboom, P.E.; Westendorp, R.G.J.; Maier, A.B.; Buchem, M.A. van & Craen, A.J.M. de (2013), Lower susceptibility to cerebral small vessel disease in human familial longevity: the Leiden Longevity Study.
- Passtoors, W.M.; Beekman, M.; Deelen, J.; Breggen, R. van der; Maier, A.B.; Guigas, B.; Derhovanessian, E.; Heemst, D. van; Craen, A.J.M. de; Gunn, D.A.; Pawelec, G. & Slagboom, P.E. (2013), Gene expression analysis of mTOR pathway: association with human longevity., Aging Cell 12(1): 24-31.
- Zhang, Y.J.; Lameijer, E.W.; Hoen, P.A.C. 't; Ning, Z.M.; Slagboom, P.E. & Ye, K. (2012), PASSion: a pattern growth algorithm-based pipeline for splice junction detection in paired-end RNA-Seq data, Bioinformatics 28(4).
- Kerkhof, H.J.M.; Evangelou, E.; Meulenbelt, I.; Meurs, J.B.J. van; Zeggini, E. & Valdes, A.M. (2012), Human genetic studies on osteoarthritis from clinicians' viewpoints Reply, Osteoarthritis and Cartilage 20(3): 250-251.
- Hogervorst, T.; Eilander, W.; Fikkers, J.T. & Meulenbelt, I. (2012), Hip Ontogenesis: How Evolution, Genes, and Load History Shape Hip Morphotype and Cartilotype, Clinical Orthopaedics and Related Research 470(12): 3284-3296.
- Obermann-Borst, S.A.; Heijmans, B.T.; Eilers, P.H.C.; Tobi, E.W.; Steegers, E.A.P.; Slagboom, P.E. & Steegers-Theunissen, R.P.M. (2012), Periconception maternal smoking and low education are associated with methylation of INSIGF in children at the age of 17 months, Journal of Developmental Origins of Health and Disease 3(5): 315-320.
- Soerensen, M.; Dato, S.; Tan, Q.H.; Thinggaard, M.; Kleindorp, R.; Beekman, M.; Suchiman, H.E.D.; Jacobsen, R.; McGue, M.; Stevnsner, T.; Bohr, V.A.; Craen, A.J.M. de; Westendorp, R.G.J.; Schreiber, S.; Slagboom, P.E.; Nebel, A.; Vaupel, J.W.; Christensen, K. & Christiansen, L. (2012), Evidence from case-control and longitudinal studies supports associations of genetic variation in APOE, CETP, and IL6 with human longevity., AGE.
- Bos, S.D.; Beekman, M.; Westendorp, R.; Craen, T. de; Kloppenburg, M.; Meulenbelt, I. & Slagboom, P.E. (2012), COMPARISON OF HEALTHY AND NORMATIVE AGING REVEALS A METABOLIC COMPONENT IN HAND OA AND OA BIOCHEMICAL MARKER PROFILES, Osteoarthritis and Cartilage 20: S88-S88.
- Ramos, Y.F.; Bos, S.D.; Lakenberg, N.; Kloppenburg, M.; Slagboom, P.E. & Meulenbelt, I. (2012), GENES ASSOCIATED WITH OSTEOARTHRITIS IDENTIFIED BY MICROARRAY-ANALYSIS OF WHOLE BLOOD SAMPLES LINK OA TO APOPTOTIC PATHWAYS, Osteoarthritis and Cartilage 20: S77-S78.
- Hollander, W. den; Bos, S.D.; Ramos, Y.F.; Lakenberg, N.; Breggen, R. van der; Duijnisveld, B.J.; Nelissen, R.G.; Slagboom, E.P. & Meulenbelt, I. (2012), CPG SITES OF OSTEOARTHRITIS SUSCEPTIBILITY GENE DIO2 ARE DIFFERENTIALLY METHYLATED IN ARTHRITIC COMPARED TO PRESERVED CARTILAGE., Osteoarthritis and Cartilage 20: S196-S196.
- Leeuwen, N. van; Nijpels, G.; Haeften, T.W. van; Slagboom, P.E.; Geus, E.J. de; Dekker, J.M.; Boomsma, D.I.; Fritsche, A.; Eekhoff, E.M. & Hart, L.M. 't (2012), Differential effects of type 2 diabetes and fasting glucose/insulin associated loci on insulin secretion stimulated by glucose, GLP-1 or arginine as measured by hyperglycaemic clamps, Diabetologia 55: S125-S126.
- Raz, Y.; Craen, A.J.M. de; Heemst, D. van; Slagboom, P.E.; Westendorp, R.G.J. & Maier, A.B. (2012), INNATE IMMUNITY IN FAMILIAL LONGEVITY - THE LEIDEN LONGEVITY STUDY, Age and Ageing 41: 36-36.
- Talens, R.P.; Jukema, J.W.; Trompet, S.; Kremer, D.; Westendorp, R.G.J.; Lumey, L.H.; Sattar, N.; Putter, H.; Slagboom, P.E.; Heijmans, B.T. & PROSPER Grp (2012), Hypermethylation at loci sensitive to the prenatal environment is associated with increased incidence of myocardial infarction, International Journal of Epidemiology 41(1): 106-115.
- Noordam, R.; Jansen, S.W.M.; Akintola, A.A.; Oei, N.Y.L.; Maier, A.B.; Pijl, H.; Slagboom, P.E.; Westendorp, R.G.J.; Grond, J. van der; Craen, A.J.M. de; Heemst, D. van & Leiden Longevity Study Grp (2012), Familial Longevity Is Marked by Lower Diurnal Salivary Cortisol Levels: The Leiden Longevity Study., PLoS ONE 7(2): e31166.
- Passtoors, W.M.; Boer, J.M.; Goeman, J.J.; Akker, E.B. van den; Deelen, J.; Zwaan, B.J.; Scarborough, A.; Breggen, R. van der; Vossen, R.H.A.M.; Houwing-Duistermaat, J.J.; Ommen, G.J.B. van; Westendorp, R.G.J.; Heemst, D. van; Craen, A.J.M. de; White, A.J.; Gunn, D.A.; Beekman, M. & Slagboom, P.E. (2012), Transcriptional Profiling of Human Familial Longevity Indicates a Role for ASF1A and IL7R., PLoS ONE 7(1): e27759.
- Wijsman, C.A.; Westendorp, R.G.J.; Slagboom, P.E.; Heemst, D. van & Mooijaart, S.P. (2012), 24-HOUR GLUCOSE RHYTHMS IN AGEING AND LONGEVITY, Age and Ageing 41: 2-2.
- Uh, H.W.; Tsonaka, R.; Wuhrer, M.; Slagboom, E. & Houwing-Duistermaat, J. (2012), Integrating Multiple Glycans and Genetic Data Using Joint Modeling Techniques: An Application in Leiden Longevity Study, Genetic Epidemiology 36(7): 777-777.
- Rius-Ottenheim, N.; Craen, A.J.M. de; Geleijnse, J.M.; Slagboom, P.E.; Kromhout, D.; Mast, R.C. van der; Zitman, F.G.; Westendorp, R.G. & Giltay, E.J. (2012), C-reactive protein haplotypes and dispositional optimism in obese and nonobese elderly subjects., Inflammation Research 61(1): 43-51.
- Waaijer, M.E.C.; Parish, W.E.; Strongitharm, B.H.; Heemst, D. van; Slagboom, P.E.; Craen, A.J.M. de; Sedivy, J.M.; Westendorp, R.G.J.; Gunn, D.A. & Maier, A.B. (2012), The number of p16INK4a positive cells in human skin reflects biological age., Aging Cell 11(4): 722-5.
- Meulenbelt, I. (2012), Osteoarthritis year 2011 in review: genetics, Osteoarthritis and Cartilage 20(3): 218-222.
- Huffman, D.M.; Deelen, J.; Ye, K.; Bergman, A.; Slagboom, E.P.; Barzilai, N. & Atzmon, G. (2012), Distinguishing Between Longevity and Buffered-Deleterious Genotypes for Exceptional Human Longevity: The Case of the MTP Gene, Journals of Gerontology, Series A 67(11): 1153-1160.
- Webb, B.T.; Guo, A.Y.; Maher, B.S.; Zhao, Z.M.; Oord, E.J. van den; Kendler, K.S.; Riley, B.P.; Gillespie, N.A.; Prescott, C.A.; Middeldorp, C.M.; Willemsen, G.; Geus, E.J.C. de; Hottenga, J.J.; Boomsma, D.I.; Slagboom, E.P.; Wray, N.R.; Montgomery, G.W.; Martin, N.G.; Wright, M.J.; Heath, A.C.; Madden, P.A.; Gelernter, J.; Knowles, J.A.; Hamilton, S.P.; Weissman, M.M.; Fyer, A.J.; Huezo-Diaz, P.; McGuffin, P.; Farmer, A.; Craig, I.W.; Lewis, C.; Sham, P.; Crowe, R.R.; Flint, J. & Hettema, J.M. (2012), Meta-analyses of genome-wide linkage scans of anxiety-related phenotypes, European Journal of Human Genetics 20(10): 1078-1084.
- Brandsma M, Baas F, de Bakker PIW, Beem EP, Boomsma DI, Bovenberg J, Bueno-de-Mesquita B, van Duijn C, Kiemeney LA, Klungel O, de Leeuw FE, van Leeuwen FE, Ridder-Numan J, Stolk RP, Slagboom PE, Swertz M, Wijmenga C, van Ommen GJB & on behalf of BBMRI-NL (2012), How to kickstart a national biobanking infrastructure - experiences and prospects of BBMRI-NL, Norsk Epidemiologi.
- Dekker, P.; Baalen, L.M. van; Dirks, R.W.; Slagboom, P.E.; Heemst, D. van; Tanke, H.J.; Westendorp, R.G.J. & Maier, A.B. (2012), Chronic Inhibition of the Respiratory Chain in Human Fibroblast Cultures: Differential Responses Related to Subject Chronological and Biological Age, Journals of Gerontology, Series A 67(5): 456-464.
- Wijsman, C.A.; Heemst, D. van; Hoogeveen, E.S.; Slagboom, P.E.; Maier, A.B.; Craen, A.J.M. de; Ouderaa, F. van der; Pijl, H.; Westendorp, R.G.J. & Mooijaart, S.P. (2012), Ambulant 24-h glucose rhythms mark calendar and biological age in apparently healthy individuals., Aging Cell.
- Noordam, R.; Gunn, D.A.; Tomlin, C.C.; Rozing, M.P.; Maier, A.B.; Slagboom, P.E.; Westendorp, R.G.J.; Heemst, D. van; Craen, A.J.M. de & Leiden Longevity Study Grp (2012), Cortisol serum levels in familial longevity and perceived age: The Leiden Longevity Study, Psychoneuroendocrinology 37(10): 1669-1675.
- Waaijer, M.E.C.; Parish, W.E.; Strongitharm, B.H.; Heemst, D. van; Slagboom, P.E.; Craen, A.J.M. de; Sedivy, J.M.; Westendorp, R.G.J.; Gunn, D.A. & Maier, A.B. (2012), The number of p16INK4a positive cells in human skin reflects biological age, Aging Cell 11(4): 722-725.
- Zhang, Y.J.; Lameijer, E.W.; Hoen, P.A.C. 't; Ning, Z.M.; Slagboom, P.E. & Ye, K. (2012), PASSion: a pattern growth algorithm-based pipeline for splice junction detection in paired-end RNA-Seq data.
- Uh HW, Deelen J, Beekman M, Helmer Q, Rivadeneira F, Hottenga JJ, Boomsma DI, Hofman A, Uitterlinden AG, Slagboom PE, Böhringer S & Houwing-Duistermaat JJ (2012), How to deal with the early GWAS data when imputting and combining different arrays is necessary, European Journal of Human Genetics.
- Postmus, I.; Verschuren, J.J.W.; Craen, A.J.M. de; Slagboom, P.E.; Westendorp, R.G.J.; Jukema, J.W. & Trompet, S. (2012), Pharmacogenetics of statins: achievements, whole-genome analyses and future perspectives, Pharmacogenomics 13(7): 831-840.
- Noordam, R.; Craen, A.J.M. de; Pedram, P.; Maier, A.B.; Mooijaart, S.P.; Pelt, J. van; Feskens, E.J.; Streppel, M.T.; Slagboom, P.E.; Westendorp, G.J.; Beekman, M. & Heemst, D. van (2012), Levels of 25-hydroxyvitamin D in familial longevity: the Leiden Longevity Study, CMAJ.
- Waaijer, M.E.C.; Parish, W.E.; Strongitharm, B.H.; Heemst, D. van; Slagboom, P.E.; Craen, A.J.M. de; Sedivy, J.M.; Westendorp, R.G.J.; Gunn, D.A. & Maier, A.B. (2012), The number of p16INK4a positive cells in human skin reflects biological age, Aging Cell 11(4): 722-725.
- Zhang, Y.J.; Lameijer, E.W.; Hoen, P.A.C. 't; Ning, Z.M.; Slagboom, P.E. & Ye, K. (2012), PASSion: a pattern growth algorithm-based pipeline for splice junction detection in paired-end RNA-Seq data.
- Dekker, P.; Baalen, L.M. van; Dirks, R.W.; Slagboom, P.E.; Heemst, D. van; Tanke, H.J.; Westendorp, R.G.J. & Maier, A.B. (2012), Chronic Inhibition of the Respiratory Chain in Human Fibroblast Cultures: Differential Responses Related to Subject Chronological and Biological Age, Journals of Gerontology, Series A 67(5): 456-464.
- Sampietro, M.L.; Pons, D.; Knijff, P. de; Slagboom, P.E.; Zwinderman, A.H. & Jukema, J.W. (2012), A genome wide association analysis in the GENDER study, Netherlands Heart Journal 20: 56-58.
- Waaijer, M.E.C.; Gunn, D.A.; Catt, S.D.; Ginkel, M. van; Craen, A.J.M. de; Hudson, N.M.; Heemst, D. van; Slagboom, P.E.; Westendorp, R.G.J. & Maier, A.B. (2012), Morphometric skin characteristics dependent on chronological and biological age: the Leiden Longevity Study, AGE 34(6): 1543-1552.
- Uh, H.W.; Deelen, J.; Beekman, M.; Helmer, Q.; Rivadeneira, F.; Hottenga, J.J.; Boomsma, D.I.; Hofman, A.; Uitterlinden, A.G.; Slagboom, P.E.; Bohringer, S. & Houwing-Duistermaat, J.J. (2012), How to deal with the early GWAS data when imputing and combining different arrays is necessary, European Journal of Human Genetics 20(5): 572-576.
- Talens, R.P.; Jukema, J.W.; Trompet, S.; Kremer, D.; Westendorp, R.G.J.; Lumey, L.H.; Sattar, N.; Putter, H.; Slagboom, P.E.; Heijmans, B.T. & PROSPER Grp (2012), Hypermethylation at loci sensitive to the prenatal environment is associated with increased incidence of myocardial infarction, International Journal of Epidemiology 41(1): 106-115.
- Bay-Jensen, A.C.; Slagboom, E.; Chen-An, P.; Alexandersen, P.; Qvist, P.; Christiansen, C.; Meulenbelt, I. & Karsdal, M.A. (2012), Role of hormones in cartilage and joint metabolism: understanding an unhealthy metabolic phenotype in osteoarthritis., Menopause.
- Dongen, J. van; Slagboom, P.E.; Draisma, H.H.M.; Martin, N.G. & Boomsma, D.I. (2012), The continuing value of twin studies in the omics era, Nature Reviews Genetics 13(9): 640-653.
- Tobi, E.W.; Slagboom, P.E.; Dongen, J. van; Kremer, D.; Stein, A.D.; Putter, H.; Heijmans, B.T. & Lumey, L.H. (2012), Prenatal Famine and Genetic Variation Are Independently and Additively Associated with DNA Methylation at Regulatory Loci within IGF2/H19, PLoS ONE 7(5): -.
- Lu, Y.C.; Vaarhorst, A.; Merry, A.H.H.; Dolle, M.E.T.; Hovenier, R.; Imholz, S.; Schouten, L.J.; Heijmans, B.T.; Muller, M.; Slagboom, P.E.; Brandt, P.A. van den; Gorgels, A.P.M.; Boer, J.M.A. & Feskens, E.J.M. (2012), Markers of Endogenous Desaturase Activity and Risk of Coronary Heart Disease in the CAREMA Cohort Study, PLoS ONE 7(7): -.
- Estrada, K.; Styrkarsdottir, U.; Evangelou, E.; Hsu, Y.H.; Duncan, E.L.; Ntzani, E.E.; Oei, L.; Albagha, O.M.E.; Amin, N.; Kemp, J.P.; Koller, D.L.; Li, G.; Liu, C.T.; Minster, R.L.; Moayyeri, A.; Vandenput, L.; Willner, D.; Xiao, S.M.; Yerges-Armstrong, L.M.; Zheng, H.F.; Alonso, N.; Eriksson, J.; Kammerer, C.M.; Kaptoge, S.K.; Leo, P.J.; Thorleifsson, G.; Wilson, S.G.; Wilson, J.F.; Aalto, V.; Alen, M.; Aragaki, A.K.; Aspelund, T.; Center, J.R.; Dailiana, Z.; Duggan, D.J.; Garcia, M.; Garcia-Giralt, N.; Giroux, S.; Hallmans, G.; Hocking, L.J.; Husted, L.B.; Jameson, K.A.; Khusainova, R.; Kim, G.S.; Kooperberg, C.; Koromila, T.; Kruk, M.; Laaksonen, M.; Lacroix, A.Z.; Lee, S.H.; Leung, P.C.; Lewis, J.R.; Masi, L.; Mencej-Bedrac, S.; Nguyen, T.V.; Nogues, X.; Patel, M.S.; Prezelj, J.; Rose, L.M.; Scollen, S.; Siggeirsdottir, K.; Smith, A.V.; Svensson, O.; Trompet, S.; Trummer, O.; Schoor, N.M. van; Woo, J.; Zhu, K.; Balcells, S.; Brandi, M.L.; Buckley, B.M.; Cheng, S.L.; Christiansen, C.; Cooper, C.; Dedoussis, G.; Ford, I.; Frost, M.; Goltzman, D.; Gonzalez-Macias, J.; Kahonen, M.; Karlsson, M.; Khusnutdinova, E.; Koh, J.M.; Kollia, P.; Langdahl, B.L.; Leslie, W.D.; Lips, P.; Ljunggren, O.; Lorenc, R.S.; Marc, J.; Mellstrom, D.; Obermayer-Pietsch, B.; Olmos, J.M.; Pettersson-Kymmer, U.; Reid, D.M.; Riancho, J.A.; Ridker, P.M.; Rousseau, F.; Slagboom, P.E.; Tang, N.L.S.; Urreizti, R.; Hul, W. van; Viikari, J.; Zarrabeitia, M.T.; Aulchenko, Y.S.; Castano-Betancourt, M.; Grundberg, E.; Herrera, L.; Ingvarsson, T.; Johannsdottir, H.; Kwan, T.; Li, R.; Luben, R.; Medina-Gomez, C.; Palsson, S.T.; Reppe, S.; Rotter, J.I.; Sigurdsson, G.; Meurs, J.B.J. van; Verlaan, D.; Williams, F.M.K.; Wood, A.R.; Zhou, Y.H.; Gautvik, K.M.; Pastinen, T.; Raychaudhuri, S.; Cauley, J.A.; Chasman, D.I.; Clark, G.R.; Cummings, S.R.; Danoy, P.; Dennison, E.M.; Eastell, R.; Eisman, J.A.; Gudnason, V.; Hofman, A.; Jackson, R.D.; Jones, G.; Jukema, J.W.; Khaw, K.T.; Lehtimaki, T.; Liu, Y.M.; Lorentzon, M.; McCloskey, E.; Mitchell, B.D.; Nandakumar, K.; Nicholson, G.C.; Oostra, B.A.; Peacock, M.; Pols, H.A.P.; Prince, R.L.; Raitakari, O.; Reid, I.R.; Robbins, J.; Sambrook, P.N.; Sham, P.C.; Shuldiner, A.R.; Tylavsky, F.A.; Duijn, C.M. van; Wareham, N.J.; Cupples, L.A.; Econs, M.J.; Evans, D.M.; Harris, T.B.; Kung, A.W.C.; Psaty, B.M.; Reeve, J.; Spector, T.D.; Streeten, E.A.; Zillikens, M.C.; Thorsteinsdottir, U.; Ohlsson, C.; Karasik, D.; Richards, J.B.; Brown, M.A.; Stefansson, K.; Uitterlinden, A.G.; Ralston, S.H.; Ioannidis, J.P.A.; Kiel, D.P. & Rivadeneira, F. (2012), Genome-wide meta-analysis identifies 56 bone mineral density loci and reveals 14 loci associated with risk of fracture, Nature Genetics 44(5): 491-+.
- Talens, R.P.; Christensen, K.; Putter, H.; Willemsen, G.; Christiansen, L.; Kremer, D.; Suchiman, H.E.D.; Slagboom, P.E.; Boomsma, D.I. & Heijmans, B.T. (2012), Epigenetic variation during the adult lifespan: cross-sectional and longitudinal data on monozygotic twin pairs, Aging Cell 11(4): 694-703.
- Brandys, M.K.; Landt, M.C.T.S.O.; Elburg, A.A. van; Ophoff, R.; Verduijn, W.; Meulenbelt, I.; Middeldorp, C.M.; Boomsma, D.I.; Furth, E.F. van; Slagboom, E.; Kas, M.J.H. & Adan, R.A.H. (2012), Anorexia nervosa and the Val158Met polymorphism of the COMT gene: meta-analysis and new data, Psychiatric Genetics 22(3): 130-136.
- Wijsman, C.; Heemst, D. van; Slagboom, E.; Pijl, H.; Ouderaa, F. van der; Westendorp, R. & Mooijaart, S. (2012), AMBULANT 24-HOUR GLUCOSE RHYTHMS IN CHRONOLOGICAL AGE AND FAMILIAL LONGEVITY IN INDIVIDUALS WITHOUT DIABETES.
- Barzilai, N.; Guarente, L.; Kirkwood, T.B.L.; Partridge, L.; Rando, T.A. & Slagboom, P.E. (2012), The place of genetics in ageing research, Nature Reviews Genetics 13(8): 589-594.
- Vaarhorst, A.A.M.; Lu, Y.C.; Heijmans, B.T.; Dolle, M.E.T.; Bohringer, S.; Putter, H.; Imholz, S.; Merry, A.H.H.; Greevenbroek, M.M. van; Jukema, J.W.; Gorgels, A.P.M.; Brandt, P.A. van den; Muller, M.; Schouten, L.J.; Feskens, E.J.M.; Boer, J.M.A. & Slagboom, P.E. (2012), Literature-Based Genetic Risk Scores for Coronary Heart Disease The Cardiovascular Registry Maastricht (CAREMA) Prospective Cohort Study, Circulation: Cardiovascular Genetics 5(2): 202-209.
- Soerensen, M.; Dato, S.; Tan, Q.H.; Thinggaard, M.; Kleindorp, R.; Beekman, M.; Jacobsen, R.; Suchiman, H.E.D.; Craen, A.J.M. de; Westendorp, R.G.J.; Schreiber, S.; Stevnsner, T.; Bohr, V.A.; Slagboom, P.E.; Nebel, A.; Vaupel, J.W.; Christensen, K.; McGue, M. & Christiansen, L. (2012), Human longevity and variation in GH/IGF-1/insulin signaling, DNA damage signaling and repair and pro/antioxidant pathway genes: Cross sectional and longitudinal studies, Experimental Gerontology 47(5): 379-387.
- Shiffman, D.; Trompet, S.; Louie, J.Z.; Rowland, C.M.; Catanese, J.J.; Iakoubova, O.A.; Kirchgessner, T.G.; Westendorp, R.G.J.; Craen, A.J.M. de; Slagboom, P.E.; Buckley, B.M.; Stott, D.J.; Sattar, N.; Devlin, J.J.; Packard, C.J.; Ford, I.; Sacks, F.M. & Jukema, J.W. (2012), Genome-Wide Study of Gene Variants Associated with Differential Cardiovascular Event Reduction by Pravastatin Therapy, PLoS ONE 7(5): -.
- Postmu, I.; Trompet, S.; Craen, A.J.M. de; Slagboom, P.; Westendorp, R.G.J.; Jukema, J.W. & PROSPER Study Grp (2012), Genetic variations in the PCSK9 gene in relation to cholesterol levels, cognitive function and clinical events in an elderly population, European Heart Journal 33: 492-492.
- Bos, S.D.; Bovee, J.V.M.G.; Duijnisveld, B.J.; Raine, E.V.A.; Dalen, W.J.; Ramos, Y.F.M.; Breggen, R. van der; Nelissen, R.G.H.H.; Slagboom, P.E.; Loughlin, J. & Meulenbelt, I. (2012), Increased type II deiodinase protein in OA-affected cartilage and allelic imbalance of OA risk polymorphism rs225014 at DIO2 in human OA joint tissues., Annals of the Rheumatic Diseases 71(7): 1254-8.
- Verschuren, J.J.W.; Trompet, S.; Postmus, I.; Sampietro, M.L.; Heijmans, B.T.; Houwing-Duistermaat, J.J.; Slagboom, E.P. & Jukema, J.W. (2012), Systematic testing of literature reported genetic variation associated with restenosis after percutaneous coronary intervention: results of the genetic determinants of restenosis study, European Heart Journal 33: 872-873.
- Verschuren, J.J.W.; Trompet, S.; Postmus, I.; Sampietro, M.L.; Heijmans, B.T.; Houwing-Duistermaat, J.J.; Slagboom, P.E. & Jukema, J.W. (2012), Systematic Testing of Literature Reported Genetic Variation Associated with Coronary Restenosis: Results of the GENDER Study, PLoS ONE 7(8): -.
- Pawelec, G.; Maier, A.; Hahnel, K.; Zelba, H.; Craen, A. de; Roelofs, H.; Slagboom, E.; Westendorp, R. & Derhovanessian, E. (2012), Phenotypic and functional immune attributes predicting survival in very elderly people, Journal of Immunology 188: -.
- Dekker, P.; Meissner, A.; Dirks, R.W.; Slagboom, P.E.; Heemst, D. van; Deelder, A.M.; Tanke, H.J.; Westendorp, R.G.J. & Maier, A.B. (2012), Human in vivo longevity is reflected in vitro by differential metabolism as measured by H-1-NMR profiling of cell culture supernatants.
- Ling, C.H.Y.; Craen, A.J.M. de; Slagboom, P.E.; Westendorp, R.G.J. & Maier, A.B. (2012), Handgrip strength at midlife and familial longevity, AGE 34(5): 1261-1268.
- Postmus, I.; Verschuren, J.J.W.; Craen, A.J.M. de; Slagboom, P.E.; Westendorp, R.G.J.; Jukema, J.W. & Trompet, S. (2012), Pharmacogenetics of statins: achievements, whole-genome analyses and future perspectives., Pharmacogenomics 13(7): 831-40.
- Postmus I, Trompet S, de Craen AJ, Buckley BM, Ford I, Stott DJ, Sattar N, Slagboom PE, Westendorp RG & Jukema JW (2012), PCSK9 SNP rs11591147 is associated with low cholesterol levels but not with cognitive performance or non-cardiovascular clinical events in an elderly population., Journal of Lipid Research.
- Claessen, K.M.J.A.; Kloppenburg, M.; Kroon, H.M.; Bijsterbosch, J.; Pereira, A.M.; Romijn, H.A.; Straaten, T. van der; Beekman, M.; Slagboom, P.E.; Biermasz, N.R. & Meulenbelt, I. (2012), A Functional Growth Hormone Receptor Polymorphism, Exon 3 Deleted Ghr, Is Associated with Radiographic Knee Osteoarthritis in Females with Familial Osteoarthritis At Multiple Sites: The Garp Study., Arthritis and Rheumatism 64(10): S472-S473.
- Altmann-Schneider, I.; Craen, A.J.M. de; Slagboom, P.E.; Westendorp, R.G.J.; Buchem, M.A. van; Maier, A.B. & Grond, J. van der (2012), Brain tissue volumes in familial longevity: the Leiden Longevity Study, Aging Cell 11(6): 933-939.
- Zeggini, E.; Panoutsopoulou, K.; Southam, L.; Rayner, N.W.; Day-Williams, A.G.; Lopes, M.C.; Boraska, V.; Esko, T.; Evangelou, E.; Hofman, A.; Houwing-Duistermaat, J.J.; Ingvarsson, T.; Jonsdottir, I.; Jonsson, H.; Kerkhof, H.J.M.; Kloppenburg, M.; Bos, S.D.; Mangino, M.; Metrustry, S.; Slagboom, P.E.; Thorleifsson, G.; Raine, E.V.A.; Ratnayake, M.; Ricketts, M.; Beazley, C.; Blackburn, H.; Bumpstead, S.; Elliott, K.S.; Hunt, S.E.; Potter, S.C.; Shin, S.Y.; Yadav, V.K.; Zhai, G.J.; Sherburn, K.; Dixon, K.; Arden, E.; Aslam, N.; Battley, P.K.; Carluke, I.; Doherty, S.; Gordon, A.; Joseph, J.; Keen, R.; Koller, N.C.; Mitchell, S.; O'Neill, F.; Paling, E.; Reed, M.R.; Rivadeneira, F.; Swift, D.; Walker, K.; Watkins, B.; Wheeler, M.; Birrell, F.; Ioannidis, J.P.A.; Meulenbelt, I.; Metspalu, A.; Rai, A.; Salter, D.; Stefansson, K.; Styrkarsdottir, U.; Uitterlinden, A.G.; Meurs, J.B.J. van; Chapman, K.; Deloukas, P.; Ollier, W.E.R.; Wallis, G.A.; Arden, N.; Carr, A.; Doherty, M.; McCaskie, A.; Wilkinson, J.M.; Ralston, S.H.; Valdes, A.M.; Spector, T.D.; Loughlin, J. & arcOGEN Consortium & arcOGEN Colla (2012), Identification of new susceptibility loci for osteoarthritis (arcOGEN): a genome-wide association study, Lancet 380(9844): 815-823.
- Raalte, D.H. van; Leeuwen, N. van; Simonis-Bik, A.M.; Nijpels, G.; Haeften, T.W. van; Schafer, S.A.; Boomsma, D.I.; Kramer, M.H.H.; Heine, R.J.; Maassen, J.A.; Staiger, H.; Machicao, F.; Haring, H.U.; Slagboom, P.E.; Willemsen, G.; Geus, E.J. de; Dekker, J.M.; Fritsche, A.; Eekhoff, E.M.; Diamant, M. & Hart, L.M. 't (2012), Glucocorticoid receptor gene polymorphisms are associated with reduced first-phase glucose-stimulated insulin secretion and disposition index in women, but not in men.
- Vliet-Ostaptchouk, J.V. van; Haeften, T.W. van; Landman, G.W.D.; Reiling, E.; Kleefstra, N.; Bilo, H.J.G.; Klungel, O.H.; Boer, A. de; Diemen, C.C. van; Wijmenga, C.; Boezen, H.M.; Dekker, J.M.; Riet, E. van 't; Nijpels, G.; Welschen, L.M.C.; Zavrelova, H.; Bruin, E.J.; Elbers, C.C.; Bauer, F.; Onland-Moret, N.C.; Schouw, Y.T. van der; Grobbee, D.E.; Spijkerman, A.M.W.; , D.L. van der a; Simonis-Bik, A.M.; Eekhoff, E.M.W.; Diamant, M.; Kramer, M.H.H.; Boomsma, D.I.; Geus, E.J. de; Willemsen, G.; Slagboom, P.E.; Hofker, M.H. & Hart, L.M. 't (2012), Common Variants in the Type 2 Diabetes KCNQ1 Gene Are Associated with Impairments in Insulin Secretion During Hyperglycaemic Glucose Clamp, PLoS ONE 7(3): -.
- Wijsman, C.A.; Opstal, A.M. van; Kan, H.E.; Maier, A.B.; Westendorp, R.G.J.; Slagboom, P.E.; Webb, A.G.; Mooijaart, S.P. & Heemst, D. van (2012), Proton magnetic resonance spectroscopy shows lower intramyocellular lipid accumulation in middle-aged subjects predisposed to familial longevity, AJP - Endocrinology and Metabolism 302(3): E344-E348.
- Wijsman, C.A.; Opstal, A.M. van; Kan, H.E.; Maier, A.B.; Westendorp, R.G.J.; Slagboom, P.E.; Webb, A.G.; Mooijaart, S.P. & Heemst, D. van (2012), Proton magnetic resonance spectroscopy shows lower intramyocellular lipid accumulation in middle-aged subjects predisposed to familial longevity., AJP - Endocrinology and Metabolism 302(3): E344-8.
- Zhang, Y.J.; Lameijer, E.W.; Hoen, P.A.C. 't; Ning, Z.M.; Slagboom, P.E. & Ye, K. (2012), PASSion: a pattern growth algorithm-based pipeline for splice junction detection in paired-end RNA-Seq data., Bioinformatics 28(4): 479-86.
- Rius-Ottenheim, N.; Craen, A.J.M. de; Geleijnse, J.M.; Slagboom, P.E.; Kromhout, D.; Mast, R.C. van der; Zitman, F.G.; Westendorp, R.G. & Giltay, E.J. (2012), C-reactive protein haplotypes and dispositional optimism in obese and nonobese elderly subjects, Inflammation Research 61(1): 43-51.
- Rius-Ottenheim, N.; Kromhout, D.; Craen, A.J.M. de; Geleijnse, J.M.; Mast, R.C. van der; Zitman, F.G.; Westendorp, R.G.; Slagboom, P.E. & Giltay, E.J. (2012), Parental longevity correlates with offspring's optimism in two cohorts of community-dwelling older subjects, AGE 34(2): 461-468.
- Noordam, R.; Jansen, S.W.M.; Akintola, A.A.; Oei, N.Y.L.; Maier, A.B.; Pijl, H.; Slagboom, P.E.; Westendorp, R.G.J.; Grond, J. van der; Craen, A.J.M. de; Heemst, D. van & Leiden Longevity Study Grp (2012), Familial Longevity Is Marked by Lower Diurnal Salivary Cortisol Levels: The Leiden Longevity Study, PLoS ONE 7(2): -.
- Dastani, Z.; Hivert, M.F.; Timpson, N.; Perry, J.R.B.; Yuan, X.; Scott, R.A.; Henneman, P.; Heid, I.M.; Kizer, J.R.; Lyytikainen, L.P.; Fuchsberger, C.; Tanaka, T.; Morris, A.P.; Small, K.; Isaacs, A.; Beekman, M.; Coassin, S.; Lohman, K.; Qi, L.; Kanoni, S.; Pankow, J.S.; Uh, H.W.; Wu, Y.; Bidulescu, A.; Rasmussen-Torvik, L.J.; Greenwood, C.M.T.; Ladouceur, M.; Grimsby, J.; Manning, A.K.; Liu, C.T.; Kooner, J.; Mooser, V.E.; Vollenweider, P.; Kapur, K.A.; Chambers, J.; Wareham, N.J.; Langenberg, C.; Frants, R.; Willems-vanDijk, K.; Oostra, B.A.; Willems, S.M.; Lamina, C.; Winkler, T.W.; Psaty, B.M.; Tracy, R.P.; Brody, J.; Chen, I.; Viikari, J.; Kahonen, M.; Pramstaller, P.P.; Evans, D.M.; St Pourcain, B.; Sattar, N.; Wood, A.R.; Bandinelli, S.; Carlson, O.D.; Egan, J.M.; Bohringer, S.; Heemst, D. van; Kedenko, L.; Kristiansson, K.; Nuotio, M.L.; Loo, B.M.; Harris, T.; Garcia, M.; Kanaya, A.; Haun, M.; Klopp, N.; Wichmann, H.E.; Deloukas, P.; Katsareli, E.; Couper, D.J.; Duncan, B.B.; Kloppenburg, M.; Adair, L.S.; Borja, J.B.; Wilson, J.G.; Musani, S.; Guo, X.Q.; Johnson, T.; Semple, R.; Teslovich, T.M.; Allison, M.A.; Redline, S.; Buxbaum, S.G.; Mohlke, K.L.; Meulenbelt, I.; Ballantyne, C.M.; Dedoussis, G.V.; Hu, F.B.; Liu, Y.M.; Paulweber, B.; Spector, T.D.; Slagboom, P.E.; Ferrucci, L.; Jula, A.; Perola, M.; Raitakari, O.; Florez, J.C.; Salomaa, V.; Eriksson, J.G.; Frayling, T.M.; Hicks, A.A.; Lehtimaki, T.; Smith, G.D.; Siscovick, D.S.; Kronenberg, F.; Duijn, C. van; Loos, R.J.F.; Waterworth, D.M.; Meigs, J.B.; Dupuis, J.; Richards, J.B.; DIAGRAM Consortium; MAGIC Consortium; GLGC Investigators & MuTHER Consortium (2012), Novel Loci for Adiponectin Levels and Their Influence on Type 2 Diabetes and Metabolic Traits: A Multi-Ethnic Meta-Analysis of 45,891 Individuals, PLoS Genetics 8(3): -.
- Postmus, I.; Trompet, S.; Craen, A.J.M. de; Slagboom, P.E.; Westendorp, R.G.J. & Jukema, J.W. (2012), GENOME WIDE ASSOCIATION STUDY OF LDL-CHOLESTEROL. THE FIRST RESULTS OF THE PROSPER/PHASE STUDY, Age and Ageing 41: 8-8.
- Noordam, R.; Gunn, D.A.; Tomlin, C.C.; Rozing, M.P.; Maier, A.B.; Slagboom, P.E.; Westendorp, R.G.J.; Heemst, D. van; Craen, A.J.M. de & Leiden Longevity Study Grp (2012), Cortisol serum levels in familial longevity and perceived age: the Leiden longevity study., Psychoneuroendocrinology 37(10): 1669-75.
- Leeuwen, N. van; Nijpels, G.; Becker, M.L.; Deshmukh, H.; Zhou, K.; Stricker, B.H.C.; Uitterlinden, A.G.; Hofman, A.; Riet, E. van 't; Palmer, C.N.A.; Guigas, B.; Slagboom, P.E.; Durrington, P.; Calle, R.A.; Neil, A.; Hitman, G.; Livingstone, S.J.; Colhoun, H.; Holman, R.R.; McCarthy, M.I.; Dekker, J.M.; Hart, L.M. 't & Pearson, E.R. (2012), A gene variant near ATM is significantly associated with metformin treatment response in type 2 diabetes: a replication and meta-analysis of five cohorts, Diabetologia 55(7): 1971-1977.
- Passtoors, W.M.; Boer, J.M.; Goeman, J.J.; Akker, E.B. van den; Deelen, J.; Zwaan, B.J.; Scarborough, A.; Breggen, R. van der; Vossen, R.H.A.M.; Houwing-Duistermaat, J.J.; Ommen, G.J.B. van; Westendorp, R.G.J.; Heemst, D. van; Craen, A.J.M. de; White, A.J.; Gunn, D.A.; Beekman, M. & Slagboom, P.E. (2012), Transcriptional Profiling of Human Familial Longevity Indicates a Role for ASF1A and IL7R, PLoS ONE 7(1): -.
- Bos, S.D.; Beekman, M.; Maier, A.B.; Karsdal, M.A.; Kwok, W.Y.; Bay-Jensen, A.C.; Kloppenburg, M.; Slagboom, P.E. & Meulenbelt, I. (2012), Metabolic health in families enriched for longevity is associated with low prevalence of hand osteoarthritis and influences OA biomarker profiles., Annals of the Rheumatic Diseases.
- Yusuf, E.; Ioan-Facsinay, A.; Bijsterbosch, J.; Klein-Wieringa, I.; Kwekkeboom, J.; Slagboom, P.E.; Huizinga, T.W.J. & Kloppenburg, M. (2011), Association between leptin, adiponectin and resistin and long-term progression of hand osteoarthritis, Annals of the Rheumatic Diseases 70(7): 1282-1284.
- Yusuf, E.; Bijsterbosch, J.; Slagboom, P.E.; Rosendaal, F.R.; Huizinga, T.W.J. & Kloppenburg, M. (2011), Body mass index and alignment and their interaction as risk factors for progression of knees with radiographic signs of osteoarthritis, Osteoarthritis and Cartilage 19(9): 1117-1122.
- Panoutsopoulou, K.; Southam, L.; Elliott, K.S.; Wrayner, N.; Zhai, G.; Beazley, C.; Thorleifsson, G.; Arden, N.K.; Carr, A.; Chapman, K.; Deloukas, P.; Doherty, M.; McCaskie, A.; Ollier, W.E.R.; Ralston, S.H.; Spector, T.D.; Valdes, A.M.; Wallis, G.A.; Wilkinson, J.M.; Arden, E.; Battley, K.; Blackburn, H.; Blanco, F.J.; Bumpstead, S.; Cupples, L.A.; Day-Williams, A.G.; Dixon, K.; Doherty, S.A.; Esko, T.; Evangelou, E.; Felson, D.; Gomez-Reino, J.J.; Gonzalez, A.; Gordon, A.; Gwilliam, R.; Halldorsson, B.V.; Hauksson, V.B.; Hofman, A.; Hunt, S.E.; Ioannidis, J.P.A.; Ingvarsson, T.; Jonsdottir, I.; Jonsson, H.; Keen, R.; Kerkhof, H.J.M.; Kloppenburg, M.G.; Koller, N.; Lakenberg, N.; Lane, N.E.; Lee, A.T.; Metspalu, A.; Meulenbelt, I.; Nevitt, M.C.; O'Neill, F.; Parimi, N.; Potter, S.C.; Rego-Perez, I.; Riancho, J.A.; Sherburn, K.; Slagboom, P.E.; Stefansson, K.; Styrkarsdottir, U.; Sumillera, M.; Swift, D.; Thorsteinsdottir, U.; Tsezou, A.; Uitterlinden, A.G.; Meurs, J.B.J. van; Watkins, B.; Wheeler, M.; Mitchell, S.; Zhu, Y.; Zmuda, J.M.; Zeggini, E.; Loughlin, J. & arcOGEN Consortium (2011), Insights into the genetic architecture of osteoarthritis from stage 1 of the arcOGEN study, Annals of the Rheumatic Diseases 70(5): 864-867.
- Kerkhof, H.J.M.; Doherty, M.; Arden, N.K.; Abramson, S.B.; Attur, M.; Bos, S.D.; Cooper, C.; Dennison, E.M.; Doherty, S.A.; Evangelou, E.; Hart, D.J.; Hofman, A.; Javaid, K.; Kerna, I.; Kisand, K.; Kloppenburg, M.; Krasnokutsky, S.; Maciewicz, R.A.; Meulenbelt, I.; Muir, K.R.; Rivadeneira, F.; Samuels, J.; Sezgin, M.; Slagboom, E.; Smith, A.J.P.; Spector, T.D.; Tamm, A.; Tamm, A.; Uitterlinden, A.G.; Wheeler, M.; Zhai, G.; Zhang, W.; Meurs, J.B.J. van & Valdes, A.M. (2011), Large-scale meta-analysis of interleukin-1 beta and interleukin-1 receptor antagonist polymorphisms on risk of radiographic hip and knee osteoarthritis and severity of knee osteoarthritis, Osteoarthritis and Cartilage 19(3): 265-271.
- Evangelou, E.; Valdes, A.M.; Kerkhof, H.J.M.; Styrkarsdottir, U.; Zhu, Y.Y.; Meulenbelt, I.; Lories, R.J.; Karassa, F.B.; Tylzanowski, P.; Bos, S.D.; Akune, T.; Arden, N.K.; Carr, A.; Chapman, K.; Cupples, L.A.; Dai, J.; Deloukas, P.; Doherty, M.; Doherty, S.; Engstrom, G.; Gonzalez, A.; Halldorsson, B.V.; Hammond, C.L.; Hart, D.J.; Helgadottir, H.; Hofman, A.; Ikegawa, S.; Ingvarsson, T.; Jiang, Q.; Jonsson, H.; Kaprio, J.; Kawaguchi, H.; Kisand, K.; Kloppenburg, M.; Kujala, U.M.; Lohmander, L.S.; Loughlin, J.; Luyten, F.P.; Mabuchi, A.; McCaskie, A.; Nakajima, M.; Nilsson, P.M.; Nishida, N.; Ollier, W.E.R.; Panoutsopoulou, K.; Putte, T. van de; Ralston, S.H.; Rivadeneira, F.; Saarela, J.; Schulte-Merker, S.; Shi, D.Q.; Slagboom, P.E.; Sudo, A.; Tamm, A.; Tamm, A.; Thorleifsson, G.; Thorsteinsdottir, U.; Tsezou, A.; Wallis, G.A.; Wilkinson, J.M.; Yoshimura, N.; Zeggini, E.; Zhai, G.J.; Zhang, F.; Jonsdottir, I.; Uitterlinden, A.G.; Felson, D.T.; Meurs, J.B. van; Stefansson, K.; Ioannidis, J.P.A.; Spector, T.D.; ArcOGEN Consortium & Translation Res Europe Appl (2011), Meta-analysis of genome-wide association studies confirms a susceptibility locus for knee osteoarthritis on chromosome 7q22, Annals of the Rheumatic Diseases 70(2): 349-355.
- Kerkhof, H.J.M.; Meulenbelt, I.; Akune, T.; Arden, N.K.; Aromaa, A.; Bierma-Zeinstra, S.M.A.; Carr, A.; Cooper, C.; Dai, J.; Doherty, M.; Doherty, S.A.; Felson, D.; Gonzalez, A.; Gordon, A.; Harilainen, A.; Hart, D.J.; Hauksson, V.B.; Heliovaara, M.; Hofman, A.; Ikegawa, S.; Ingvarsson, T.; Jiang, Q.; Jonsson, H.; Jonsdottir, I.; Kawaguchi, H.; Kloppenburg, M.; Kujala, U.M.; Lane, N.E.; Leino-Arjas, P.; Lohmander, L.S.; Luyten, F.P.; Malizos, K.N.; Nakajima, M.; Nevitt, M.C.; Pols, H.A.P.; Rivadeneira, F.; Shi, D.; Slagboom, E.; Spector, T.D.; Stefansson, K.; Sudo, A.; Tamm, A.; Tamm, A.E.; Tsezou, A.; Uchida, A.; Uitterlinden, A.G.; Wilkinson, J.M.; Yoshimura, N.; Valdes, A.M. & Meurs, J.B.J. van (2011), Recommendations for standardization and phenotype definitions in genetic studies of osteoarthritis: the TREAT-OA consortium, Osteoarthritis and Cartilage 19(3): 254-264.
- Wijsman, C.A.; Heemst, D. van; Rozing, M.P.; Slagboom, P.E.; Beekman, M.; Craen, A.J.M. de; Maier, A.B.; Westendorp, R.G.J.; Blom, H.J. & Mooijaart, S.P. (2011), Homocysteine and Familial Longevity: The Leiden Longevity Study, PLoS ONE 6(3).
- Uh, H.W.; Deelen, J.; Beekman, M.; Helmer, Q.; Rivadeneira, F.; Hottenga, J.J.; Boomsma, D.I.; Hofman, A.; Uitterlinden, A.G.; Slagboom, P.E.; Bohringer, S. & Houwing-Duistermaat, J.J. (2011), How to deal with the early GWAS data when imputing and combining different arrays is necessary., European Journal of Human Genetics.
- Yusuf, E.; Bijsterbosch, J.; Slagboom, P.E.; Kroon, H.M.; Rosendaal, F.R.; Huizinga, T.W.J. & Kloppenburg, M. (2011), Association between Several Clinical and Radiological Determinants with Long-Term Clinical Progression and Good Prognosis of Lower Limb Osteoarthritis, PLoS ONE 6(10): -.
- Martella, F.; Vermunt, J.K.; Beekman, M.; Westendorp, R.G.J.; Slagboom, P.E. & Houwing-Duistermaat, J.J. (2011), A mixture model with random-effects components for classifying sibling pairs, Statistics in Medicine 30(27): 3252-3264.
- Derhovanessian, E.; Maier, A.B.; Hahnel, K.; Beck, R.; Craen, A.J.M. de; Slagboom, E.P.; Westendorp, R.G.J. & Pawelec, G. (2011), Infection with cytomegalovirus but not herpes simplex virus induces the accumulation of late-differentiated CD4(+) and CD8(+) T-cells in humans.
- Sampietro, M.L.; Trompet, S.; Verschuren, J.J.W.; Talens, R.P.; Deelen, J.; Heijmans, B.T.; Winter, R.J. de; Tio, R.A.; Doevendans, P.A.F.M.; Ganesh, S.K.; Nabel, E.G.; Westra, H.J.; Franke, L.; Akker, E.B. van den; Westendorp, R.G.J.; Zwinderman, A.H.; Kastrati, A.; Koch, W.; Slagboom, P.E.; Knijff, P. de & Jukema, J.W. (2011), A genome-wide association study identifies a region at chromosome 12 as a potential susceptibility locus for restenosis after percutaneous coronary intervention., Human Molecular Genetics 20(23): 4748-57.
- Slagboom, P.E.; Beekman, M.; Passtoors, W.M.; Deelen, J.; Vaarhorst, A.A.M.; Boer, J.M.; Akker, E.B. van den; Heemst, D. van; Craen, A.J.M. de; Maier, A.B.; Rozing, M.; Mooijaart, S.P.; Heijmans, B.T. & Westendorp, R.G.J. (2011), Genomics of human longevity., Philosophical Transactions B: Biological Sciences 366(1561): 35-42.
- Dekker, P.; Baalen, L.M. van; Dirks, R.W.; Slagboom, P.E.; Heemst, D. van; Tanke, H.J.; Westendorp, R.G.J. & Maier, A.B. (2011), Chronic Inhibition of the Respiratory Chain in Human Fibroblast Cultures: Differential Responses Related to Subject Chronological and Biological Age., Journals of Gerontology, Series A.
- Rius-Ottenheim, N.; Kromhout, D.; Craen, A.J.M. de; Geleijnse, J.M.; Mast, R.C. van der; Zitman, F.G.; Westendorp, R.G.; Slagboom, P.E. & Giltay, E.J. (2011), Parental longevity correlates with offspring's optimism in two cohorts of community-dwelling older subjects., AGE.
- Waaijer, M.E.C.; Gunn, D.A.; Catt, S.D.; Ginkel, M. van; Craen, A.J.M. de; Hudson, N.M.; Heemst, D. van; Slagboom, P.E.; Westendorp, R.G.J. & Maier, A.B. (2011), Morphometric skin characteristics dependent on chronological and biological age: the Leiden Longevity Study., AGE.
- Ling, C.H.Y.; Craen, A.J.M. de; Slagboom, P.E.; Westendorp, R.G.J. & Maier, A.B. (2011), Handgrip strength at midlife and familial longevity : The Leiden Longevity Study., AGE.
- Trompet, S.; Pons, D.; Kanse, S.M.; Craen, A.J. de; Ikram, M.A.; Verschuren, J.J.; Zwinderman, A.H.; Doevendans, P.A.; Tio, R.A.; Winter, R.J. de; Slagboom, P.E.; Westendorp, R.G. & Jukema, J.W. (2011), Factor VII Activating Protease Polymorphism (G534E) Is Associated with Increased Risk for Stroke and Mortality., Stroke Research and Treatment 2011: 424759.
- Trompet, S.; Craen, A.J.M. de; Postmus, I.; Ford, I.; Sattar, N.; Caslake, M.; Stott, D.J.; Buckley, B.M.; Sacks, F.; Devlin, J.J.; Slagboom, P.E.; Westendorp, R.G.J.; Jukema, J.W. & PROSPER Study Grp (2011), Replication of LDL GWAs hits in PROSPER/PHASE as validation for future (pharmaco)genetic analyses., BMC Medical Genetics 12: 131.
- Noordam, R.; Gunn, D.A.; Tomlin, C.C.; Maier, A.B.; Mooijaart, S.P.; Slagboom, P.E.; Westendorp, R.G.J.; Craen, A.J.M. de; Heemst, D. van & Leiden Longevity Study Grp (2011), High serum glucose levels are associated with a higher perceived age., AGE.
- Deelen, J.; Uh, H.W.; Monajemi, R.; Heemst, D. van; Thijssen, P.E.; Bohringer, S.; Akker, E.B. van den; Craen, A.J.M. de; Rivadeneira, F.; Uitterlinden, A.G.; Westendorp, R.G.J.; Goeman, J.J.; Slagboom, P.E.; Houwing-Duistermaat, J.J. & Beekman, M. (2011), Gene set analysis of GWAS data for human longevity highlights the relevance of the insulin/IGF-1 signaling and telomere maintenance pathways., AGE.
- Ling, C.H.Y.; Craen, A.J.M. de; Slagboom, P.E.; Gunn, D.A.; Stokkel, M.P.M.; Westendorp, R.G.J. & Maier, A.B. (2011), Accuracy of direct segmental multi-frequency bioimpedance analysis in the assessment of total body and segmental body composition in middle-aged adult population., Clinical Nutrition 30(5): 610-5.
- Deelen, J.; Beekman, M.; Uh, H.W.; Helmer, Q.; Kuningas, M.; Christiansen, L.; Kremer, D.; Breggen, R. van der; Suchiman, H.E.D.; Lakenberg, N.; Akker, E.B. van den; Passtoors, W.M.; Tiemeier, H.; Heemst, D. van; Craen, A.J. de; Rivadeneira, F.; Geus, E.J. de; Perola, M.; Ouderaa, F.J. van der; Gunn, D.A.; Boomsma, D.I.; Uitterlinden, A.G.; Christensen, K.; Duijn, C.M. van; Heijmans, B.T.; Houwing-Duistermaat, J.J.; Westendorp, R.G.J. & Slagboom, P.E. (2011), Genome-wide association study identifies a single major locus contributing to survival into old age; the APOE locus revisited, Aging Cell 10(4): 686-698.
- Smith, N.L.; Huffman, J.E.; Strachan, D.P.; Huang, J.; Dehghan, A.; Trompet, S.; Lopez, L.M.; Shin, S.Y.; Baumert, J.; Vitart, V.; Bis, J.C.; Wild, S.H.; Rumley, A.; Yang, Q.; Uitterlinden, A.G.; Stott, D.J.; Davies, G.; Carter, A.M.; Thorand, B.; Polasek, O.; McKnight, B.; Campbell, H.; Rudnicka, A.R.; Chen, M.H.; Buckley, B.M.; Harris, S.E.; Peters, A.; Pulanic, D.; Lumley, T.; Craen, A.J.M. de; Liewald, D.C.; Gieger, C.; Campbell, S.; Ford, I.; Gow, A.J.; Luciano, M.; Porteous, D.J.; Guo, X.Q.; Sattar, N.; Tenesa, A.; Cushman, M.; Slagboom, P.E.; Visscher, P.M.; Spector, T.D.; Illig, T.; Rudan, I.; Bovill, E.G.; Wright, A.F.; McArdle, W.L.; Tofler, G.; Hofman, A.; Westendorp, R.G.J.; Starr, J.M.; Grant, P.J.; Karakas, M.; Hastie, N.D.; Psaty, B.M.; Wilson, J.F.; Lowe, G.D.O.; O'Donnell, C.J.; Witteman, J.C.M.; Jukema, J.W.; Deary, I.J.; Soranzo, N.; Koenig, W. & Hayward, C. (2011), Genetic Predictors of Fibrin D-Dimer Levels in Healthy Adults, Circulation 123(17): 1864+.
- Tobi, E.W.; Heijmans, B.T.; Kremer, D.; Putter, H.; Delemarre-van de Waal, H.A.; Finken, M.J.J.; Wit, J.M. & Slagboom, P.E. (2011), DNA methylation of IGF2, GNASAS, INSIGF and LEP and being born small for gestational age., Epigenetics 6(2).
- Rozing, M.P.; Mooijaart, S.P.; Beekman, M.; Wijsman, C.A.; Maier, A.B.; Bartke, A.; Westendorp, R.G.J.; Slagboom, E.P. & Heemst, D. van (2011), C-reactive protein and glucose regulation in familial longevity., AGE.
- Meulenbelt, I.; Bos, S.D.; Chapman, K.; Breggen, R. van der; Houwing-Duistermaat, J.J.; Kremer, D.; Kloppenburg, M.; Carr, A.; Tsezou, A.; Gonzalez, A.; Loughlin, J. & Slagboom, E. (2011), Meta-analyses of genes modulating intracellular T3 bio-availability reveal a possible role for the DIO3 gene in osteoarthritis susceptibility, Annals of the Rheumatic Diseases 70(1): 164-167.
- Slagboom, P.E.; Beekman, M.; Passtoors, W.M.; Deelen, J.; Vaarhorst, A.A.M.; Boer, J.M.; Akker, E.B. van den; Heemst, D. van; Craen, A.J.M. de; Maier, A.B.; Rozing, M.; Mooijaart, S.P.; Heijmans, B.T. & Westendorp, R.G.J. (2011), Genomics of human longevity, Philosophical Transactions B: Biological Sciences 366(1561): 35-42.
- Geus, E. de; Snieder, H.; Kupper, N.; Suchiman, E.; Slagboom, E.; Bartels, M.; Willemsen, G. & Boomsma, D. (2011), Heritability of cardiac sympathetic control at rest and during stress and the contribution of the Gln27Glu beta-2-adrenergic receptor polymorphism, Behavior Genetics 41(6): 899-899.
- Beijsterveldt, C.E.M. van; Middeldorp, C.M.; Landt, M.C.T.S.O.; Bartels, M.; Hottenga, J.J.; Suchiman, H.E.D.; Slagboom, P.E. & Boomsma, D.I. (2011), Influence of Candidate Genes on Attention Problems in Children: A Longitudinal Study, Behavior Genetics 41(1): 155-164.
- Waarsing, J.H.; Kloppenburg, M.; Slagboom, P.E.; Kroon, H.M.; Houwing-Duistermaat, J.J.; Weinans, H. & Meulenbelt, I. (2011), Osteoarthritis Susceptibility Genes Influence the Association Between Hip Morphology and Osteoarthritis, Arthritis and Rheumatism 63(5): 1349-1354.
- Pons, D.; Trompet, S.; Craen, A.J.M. de; Thijssen, P.E.; Quax, P.H.A.; Vries, M.R. de; Wierda, R.J.; Elsen, P.J. van den; Monraats, P.S.; Ewing, M.M.; Heijmans, B.T.; Slagboom, P.E.; Zwinderman, A.H.; Doevendans, P.A.F.M.; Tio, R.A.; Winter, R.J. de; Maat, M.P.M. de; Iakoubova, O.A.; Sattar, N.; Shepherd, J.; Westendorp, R.G.J.; Jukema, J.W.; PROSPER Study Grp; WOSCOPS Study Grp & GENDER Study Grp (2011), Genetic variation in PCAF, a key mediator in epigenetics, is associated with reduced vascular morbidity and mortality: evidence for a new concept from three independent prospective studies, Heart 97(2): 143-150.
- Landt, M.C.T.S.O. 't; Meulenbelt, I.; Bartels, M.; Suchiman, E.; Middeldorp, C.M.; Houwing-Duistermaat, J.J.; Trier, J. van; Onkenhout, E.J.; Vink, J.M.; Beijsterveldt, C.E.M. van; Brandys, M.K.; Sanders, N.; Zipfel, S.; Herzog, W.; Herpertz-Dahlmann, B.; Klampfl, K.; Fleischhaker, C.; Zeeck, A.; Zwaan, M. de; Herpertz, S.; Ehrlich, S.; Elburg, A.A. van; Adan, R.A.H.; Scherag, S.; Hinney, A.; Hebebrand, J.; Boomsma, D.I.; Furth, E.F. van & Slagboom, P.E. (2011), Association study in eating disorders: TPH2 associates with anorexia nervosa and self-induced vomiting, Genes, Brain and Behavior 10(2): 236-243.
- van den Akker EB, Verbruggen B, Heijmans BT, Beekman M, Kok JN, Slagboom PE & Reinders MJ (2011), Integrating protein-protein interaction networks with gene-gene co-expression networks improves gene signatures for classifying breast cancer metastasis., Journal of Integrative Bioinformatics 8(2): 188.
- Obermann-Borst, S.A.; Slagboom, P.E.; Eilers, P.H.C.; Tobi, E.W.; Jong, F.H. de; Steegers, E.A.P.; Heijmans, B.T. & Steegers-Theunissen, R.P.M. (2011), Duration of Breastfeeding Is Associated with the Methylation of LEP in Young Children, Journal of Developmental Origins of Health and Disease 2: S118-S119.
- Finken, M.J.J.; Meulenbelt, I.; Dekker, F.W.; Frolich, M.; Walther, F.J.; Romijn, J.A.; Slagboom, P.E.; Wit, J.M. & Dutch POPS-19 Collaborative Study (2011), Abdominal Fat Accumulation in Adults Born Preterm Exposed Antenatally to Maternal Glucocorticoid Treatment Is Dependent on Glucocorticoid Receptor Gene Variation, Journal of Clinical Endocrinology and Metabolism 96(10): E1650-E1655.
- Saviouk, V.; Hottenga, J.J.; Slagboom, E.P.; Distel, M.A.; Geus, E.J.C. de; Willemsen, G. & Boomsma, D.I. (2011), ADHD in Dutch Adults: Heritability and Linkage Study, American Journal of Medical Genetics Part B: Neuropsychiatric Genetics 156B(3): 352-362.
- Talens, R.P.; Jukema, J.W.; Trompet, S.; Kremer, D.; Westendorp, R.G.J.; Lumey, L.H.; Sattar, N.; Putter, H.; Slagboom, P.E.; Heijmans, B.T. & PROSPER Grp (2011), Hypermethylation at loci sensitive to the prenatal environment is associated with increased incidence of myocardial infarction., International Journal of Epidemiology.
- Skytthe, A.; Valensin, S.; Jeune, B.; Cevenini, E.; Balard, F.; Beekman, M.; Bezrukov, V.; Blanche, H.; Bolund, L.; Broczek, K.; Carru, C.; Christensen, K.; Christiansen, L.; Collerton, J.C.; Cotichini, R.; Craen, A.J.M. de; Dato, S.; Davies, K.; Benedictis, G. de; Deiana, L.; Flachsbart, F.; Gampe, J.; Gilbault, C.; Gonos, E.S.; Haimes, E.; Hervonen, A.; Hurme, M.A.; Janiszewska, D.; Jylha, M.; Kirkwood, T.B.L.; Kristensen, P.; Laiho, P.; Leon, A.; Marchisio, A.; Masciulli, R.; Nebel, A.; Passarino, G.; Pelicci, G.; Peltonen, L.; Perola, M.; Poulain, M.; Rea, I.M.; Remade, J.; Robine, J.M.; Schreiber, S.; Scurti, M.; Sevini, F.; Sikora, E.; Skouteri, A.; Slagboom, P.E.; Spazzafumo, L.; Stazi, M.A.; Toccaceli, V.; Toussaint, O.; Tornwall, O.; Vaupel, J.W.; Voutetakis, K.; Franceschi, C. & GEHA Consortium (2011), Design, recruitment, logistics, and data management of the GEHA (Genetics of Healthy Ageing) project, Experimental Gerontology 46(11): 934-945.
- Yusuf, E.; Bijsterbosch, J.; Slagboom, P.E.; Kroon, H.M.; Rosendaal, F.R.; Huizinga, T.W.J. & Kloppenburg, M. (2011), Association between Several Clinical and Radiological Determinants with Long-Term Clinical Progression and Good Prognosis of Lower Limb Osteoarthritis., PLoS ONE 6(10): e25426.
- Wijsman, C.A.; Rozing, M.P.; Streefland, T.C.M.; Cessie, S. le; Mooijaart, S.P.; Slagboom, P.E.; Westendorp, R.G.J.; Pijl, H.; Heemst, D. van & Leiden Longevity Study Grp (2011), Familial longevity is marked by enhanced insulin sensitivity., Aging Cell 10(1): 114-21.
- Obermann-Borst, S.A.; Heijmans, B.T.; Slagboom, E.P.; Eilers, P.H.C.; Wildhagen, M.F.; Steegers, E.A.P. & Steegers-Theunissen, R.P.M. (2010), Periconception Maternal Risk Factors Affect DNA Methylation Profiles in Very Young Children, with Gender Effects., Reproductive Sciences 17(3): 223A-223A.
- Rozing, M.P.; Westendorp, R.G.J.; Craen, A.J.M. de; Frolich, M.; Heijmans, B.T.; Beekman, M.; Wijsman, C.; Mooijaart, S.P.; Blauw, G.J.; Slagboom, P.E.; Heemst, D. van & LLS Grp (2010), Low Serum Free Triiodothyronine Levels Mark Familial Longevity: The Leiden Longevity Study, Journals of Gerontology, Series A 65(4): 365-368.
- Reiling, E.; Jafar-Mohammadi, B.; van't Riet, E.; Weedon, M.N.; Vliet-Ostaptchouk, J.V. van; Hansen, T.; Saxena, R.; Haeften, T.W. van; Arp, P.A.; , S. das; Nijpels, G.; Groenewoud, M.J.; Hove, E.C. van; Uitterlinden, A.G.; Smit, J.W.A.; Morris, A.D.; Doney, A.S.F.; Palmer, C.N.A.; Guiducci, C.; Hattersley, A.T.; Frayling, T.M.; Pedersen, O.; Slagboom, P.E.; Altshuler, D.M.; Groop, L.; Romijn, J.A.; Maassen, J.A.; Hofker, M.H.; Dekker, J.M.; McCarthy, M.I. & Hart, L.M. 't (2010), Genetic association analysis of LARS2 with type 2 diabetes, Diabetologia 53(1): 103-110.
- Derhovanessian, E.; Maier, A.B.; Beck, R.; Jahn, G.; Hahnel, K.; Slagboom, P.E.; Craen, A.J.M. de; Westendorp, R.G.J. & Pawelec, G. (2010), Hallmark Features of Immunosenescence Are Absent in Familial Longevity, Journal of Immunology 185(8): 4618-4624.
- Bos, S.D.; Lakenberg, N.; Breggen, R. van der; Houwing-Duistermaat, J.J.; Kloppenburg, M.; Craen, A.J.M. de; Beekman, M.; Meulenbelt, I. & Slagboom, P.E. (2010), A genome-wide linkage scan reveals CD53 as an important regulator of innate TNF-alpha levels, European Journal of Human Genetics 18(8): 953-959.
- Trompet, S.; Craen, A.J.M. de; Jukema, J.W.; Pons, D.; Slagboom, P.E.; Kremer, D.; Bonen, E.L.E.M. & Westendorp, R.G.J. (2010), Variation in the CBP gene involved in epigenetic control associates with cognitive function.
- Mooijaart, S.P.; Heemst, D. van; Noordam, R.; Rozing, M.P.; Wijsman, C.A.; Craen, A.J.M. de; Westendorp, R.G.J.; Beekman, M. & Slagboom, P.E. (2010), Polymorphisms associated with type 2 diabetes in familial longevity: The Leiden Longevity Study., Aging.
- Middeldorp, C.M.; Geus, E.J.C. de; Willemsen, G.; Hottenga, J.J.; Slagboom, P.E. & Boomsma, D.I. (2010), The Serotonin Transporter Gene Length Polymorphism (5-HTTLPR) and Life Events: No Evidence for an Interaction Effect on Neuroticism and Anxious Depressive Symptoms, Twin Research and Human Genetics 13(6): 544-549.
- Panoutsopoulou, K.; Southam, L.; Rayner, W.; Zhai, G.; Beazley, C.; Arden, N.; Carr, A.; Chapman, K.; Deloukas, P.; Doherty, M.; McCaskie, A.; Olher, W.; Ralston, S.; Spector, T.; Valdes, A.; Wallis, G.; Wilkinson, M.; Arden, E.; Battley, K.; Blackburn, H.; Blanco, F.; Bumpstead, S.; Cupples, A.; Day-Williams, A.; Dixon, K.; Dohertys, S.; Elliott, K.; Evangelou, E.; Felson, D.; Gomez-Reino, J.; Gonzalez, A.; Gordon, A.; Gwilliam, R.; Hofman, A.; Hunt, S.; Ioannidis, J.; Jonsdottir, I.; Keen, R.; Kerkhof, H.; Kloppenburg, M.; Koller, N.; Lakenberg, N.; Lane, N.; Lee, A.; Meulenbelt, I.; Nevitt, M.; O'Neill, F.; Parimi, N.; Potter, S.; Rego-Perez, I.; Riancho, J.; Sherburn, K.; Slagboom, E.; Styrkarsdottir, U.; Sumillera, M.; Swift, D.; Tsezou, A.; Uitterlinden, A.; Meurs, J. van; Watkins, B.; Wheeler, M.; Mitchelle, S.; Zhu, Y.; Zmuda, J.; Zeggini, E.; Loughlin, J. & ArcOGEN Consortium (2010), THE arcOGEN CONSORTIUM: STAGE 1 OF A GENOME-WIDE ASSOCIATION SCAN FOR OSTEOARTHRITIS, Osteoarthritis and Cartilage 18: S166S167.
- Kerkhof, H.J.; Meulenbelt, I.; Arden, N.; Cooper, C.; Doherty, M.; Felson, D.; Gonzalez, A.; Ikegawa, S.; Jiang, Q.; Jonsdottir, I.; Kujala, U.; Lane, N.; Leino-Arjas, P.; Lohmander, S.; Luyten, F.; Nevitt, M.; Slagboom, E.; Spector, T.; Stefansson, K.; Tamm, A.; Tsezou, A.; Wilkinson, J.; Yoshimura, N.; Valdes, A. & Meurs, J. van (2010), RECOMMENDATIONS FOR STANDARDIZATION AND PHENOTYPE DEFINITIONS IN GENETIC STUDIES OF OSTEOARTHRITIS: THE TREAT-OA CONSORTIUM, Osteoarthritis and Cartilage 18: S160S160.
- May, L.; Bodegom, D. van; Frolich, M.; Lieshout, L. van; Slagboom, P.E.; Westendorp, R.G.J. & Kuningas, M. (2010), Polymorphisms in TLR4 and TLR2 genes, cytokine production and survival in rural Ghana, European Journal of Human Genetics 18(4): 490-495.
- Caliebe, A.; Kleindorp, R.; Blanche, H.; Christiansen, L.; Puca, A.A.; Rea, I.M.; Slagboom, E.; Flachsbart, F.; Christensen, K.; Rimbach, G.; Schreiber, S. & Nebel, A. (2010), No or only population-specific effect of PON1 on human longevity: A comprehensive meta-analysis, Ageing Research Reviews 9(3): 238-244.
- Kerkhof, H.J.; Doherty, M.; Abramson, S.B.; Arden, N.K.; Attur, M.; Bos, S.; Cooper, C.; Doherty, S.A.; Evangelou, E.; Kerna, I.; Kisand, K.; Kloppenburg, M.; Maciewicz, R.A.; Meulenbelt, I.; Sezgin, M.; Slagboom, E.; Smith, A.; Spector, T.D.; Tamm, A.; Tamm, A.; Uitterlinden, A.G.; Wheeler, M.; Zhang, W.; Meurs, J.B. van & Valdes, A.M. (2010), LARGE SCALE META-ANALYSIS OF INTERLEUKIN-1 BETA AND INTERLEUKIN-1 RECEPTOR ANTAGONIST POLYMORPHISMS ON RISK OF RADIOGRAPHIC HIP AND KNEE OSTEOARTHRITIS AND SEVERITY OF KNEE OSTEOARTHRITIS, Osteoarthritis and Cartilage 18: S166S166.
- Derhovanessian, E.; Maier, A.B.; Beck, R.; Jahn, G.; Hahnel, K.; Slagboom, P.E.; Craen, A.J.M. de; Westendorp, R.G.J. & Pawelec, G. (2010), Hallmark Features of Immunosenescence Are Absent in Familial Longevity, Journal of Immunology 185(8): 4618-4624.
- Terracciano, A.; Sanna, S.; Uda, M.; Deiana, B.; Usala, G.; Busonero, F.; Maschio, A.; Scally, M.; Patriciu, N.; Chen, W.M.; Distel, M.A.; Slagboom, E.P.; Boomsma, D.I.; Villafuerte, S.; Sliwerska, E.; Burmeister, M.; Amin, N.; Janssens, A.C.J.W.; Duijn, C.M. van; Schlessinger, D.; Abecasis, G.R. & Costa, P.T. (2010), Genome-wide association scan for five major dimensions of personality, Molecular Psychiatry 15(6): 647-656.
- Lu, Y.C.; Feskens, E.J.M.; Boer, J.M.A.; Imholz, S.; Verschuren, W.M.M.; Wijmenga, C.; Vaarhorst, A.; Slagboom, E.; Muller, M. & Dolle, M.E.T. (2010), Exploring genetic determinants of plasma total cholesterol levels and their predictive value in a longitudinal study, Atherosclerosis 213(1): 200-205.
- Kerkhof, H.J.M.; Meulenbelt, I.; Carr, A.; Gonzalez, A.; Hart, D.; Hofman, A.; Kloppenburg, M.; Lane, N.E.; Loughlin, J.; Nevitt, M.C.; Pols, H.A.P.; Rivadeneira, F.; Slagboom, E.P.; Spector, T.D.; Stolk, L.; Tsezou, A.; Uitterlinden, A.G.; Valdes, A.M. & Meurs, J.B.J. van (2010), Common genetic variation in the Estrogen Receptor Beta (ESR2) gene and osteoarthritis: results of a meta-analysis, BMC Medical Genetics 11.
- Yusuf, E.; Ioan-Facsinay, A.; Bijsterbosch, J.; Kwekkeboom, J.C.; Slagboom, P.E.; Huizinga, T.W. & Kloppenburg, M. (2010), ASSOCIATION BETWEEN ADIPOKINES AND PROGRESSION OF HAND OSTEOARTHRITIS, Osteoarthritis and Cartilage 18: S58S59.
- Middeldorp, C.M.; Slof-Op 't Landt, M.C.T.; Medland, S.E.; Beijsterveldt, C.E.M. van; Bartels, M.; Willemsen, G.; Hottenga, J.J.; Geus, E.J.C. de; Suchiman, H.E.D.; Dolan, C.V.; Neale, M.C.; Slagboom, P.E. & Boomsma, D.I. (2010), Anxiety and depression in children and adults: influence of serotonergic and neurotrophic genes?, Genes, Brain and Behavior 9(7): 808-816.
- Newman, A.B.; Walter, S.; Lunetta, K.L.; Garcia, M.E.; Slagboom, P.E.; Christensen, K.; Arnold, A.M.; Aspelund, T.; Aulchenko, Y.S.; Benjamin, E.J.; Christiansen, L.; D'Agostino, R.B.; Fitzpatrick, A.L.; Franceschini, N.; Glazer, N.L.; Gudnason, V.; Hofman, A.; Kaplan, R.; Karasik, D.; Kelly-Hayes, M.; Kiel, D.P.; Launer, L.J.; Marciante, K.D.; Massaro, J.M.; Miljkovic, I.; Nalls, M.A.; Hernandez, D.; Psaty, B.M.; Rivadeneira, F.; Rotter, J.; Seshadri, S.; Smith, A.V.; Taylor, K.D.; Tiemeier, H.; Uh, H.W.; Uitterlinden, A.G.; Vaupel, J.W.; Walston, J.; Westendorp, R.G.J.; Harris, T.B.; Lumley, T.; Duijn, C.M. van & Murabito, J.M. (2010), A Meta-analysis of Four Genome-Wide Association Studies of Survival to Age 90 Years or Older: The Cohorts for Heart and Aging Research in Genomic Epidemiology Consortium, Journals of Gerontology, Series A 65(5): 478-487.
- Moxley, G.; Meulenbelt, I.; Chapman, K.; Diujn, C.M. van; Slagboom, P.E.; Neale, M.C.; Smith, A.J.P.; Carr, A.J. & Loughlin, J. (2010), Interleukin-1 region meta-analysis with osteoarthritis phenotypes, Osteoarthritis and Cartilage 18(2): 200-207.
- Kerkhof, H.J.M.; Lories, R.J.; Meulenbelt, I.; Jonsdottir, I.; Valdes, A.M.; Arp, P.; Ingvarsson, T.; Jhamai, M.; Jonsson, H.; Stolk, L.; Thorleifsson, G.; Zhai, G.J.; Zhang, F.; Zhu, Y.Y.; Breggen, R. van der; Carr, A.; Doherty, M.; Doherty, S.; Felson, D.T.; Gonzalez, A.; Halldorsson, B.V.; Hart, D.J.; Hauksson, V.B.; Hofman, A.; Ioannidis, J.P.A.; Kloppenburg, M.; Lane, N.E.; Loughlin, J.; Luyten, F.P.; Nevitt, M.C.; Parimi, N.; Pols, H.A.P.; Rivadeneira, F.; Slagboom, E.P.; Styrkarsdottir, U.; Tsezou, A.; Putte, T. van de; Zmuda, J.; Spector, T.D.; Stefansson, K.; Uitterlinden, A.G. & Meurs, J.B.J. van (2010), A Genome-Wide Association Study Identifies an Osteoarthritis Susceptibility Locus on Chromosome 7q22, Arthritis and Rheumatism 62(2): 499-510.
- Talens, R.P.; Boomsma, D.I.; Tobi, E.W.; Kremer, D.; Jukema, J.W.; Willemsen, G.; Putter, H.; Slagboom, P.E. & Heijmans, B.T. (2010), Variation, patterns, and temporal stability of DNA methylation: considerations for epigenetic epidemiology, FASEB Journal 24(9): 3135-3144.
- Vaarhorst, A.A.M.; Beekman, M.; Suchiman, E.H.D.; Heemst, D. van; Houwing-Duistermaat, J.J.; Westendorp, R.G.J.; Slagboom, P.E.; Heijmans, B.T.; Project Grp & Leiden Longevity Study LLS Grp (2010), Lipid metabolism in long-lived families: the Leiden Longevity Study., AGE.
- Landt, M.C.T.S.O. 't; Meulenbelt, I.; Bartels, M.; Suchiman, E.; Middeldorp, C.M.; Houwing-Duistermaat, J.J.; Trier, J. van; Onkenhout, E.J.; Vink, J.M.; Beijsterveldt, C.E.M. van; Brandys, M.K.; Sanders, N.; Zipfel, S.; Herzog, W.; Herpertz-Dahlmann, B.; Klampfl, K.; Fleischhaker, C.; Zeeck, A.; Zwaan, M. de; Herpertz, S.; Ehrlich, S.; Elburg, A.A. van; Adan, R.A.H.; Scherag, S.; Hinney, A.; Hebebrand, J.; Boomsma, D.I.; Furth, E.F. van & Slagboom, P.E. (2010), Association study in eating disorders: TPH2 associates with anorexia nervosa and self-induced vomiting., Genes, Brain and Behavior.
- Beekman, M.; Nederstigt, C.; Suchiman, H.E.D.; Kremer, D.; Breggen, R. van der; Lakenberg, N.; Alemayehu, W.G.; Craen, A.J.M. de; Westendorp, R.G.J.; Boomsma, D.I.; Geus, E.J.C. de; Houwing-Duistermaat, J.J.; Heijmans, B.T. & Slagboom, P.E. (2010), Genome-wide association study (GWAS)-identified disease risk alleles do not compromise human longevity, Proceedings of the National Academy of Sciences 107(42): 18046-18049.
- Rozing, M.P.; Houwing-Duistermaat, J.J.; Slagboom, P.E.; Beekman, M.; Frolich, M.; Craen, A.J.M. de; Westendorp, R.G.J. & Heemst, D. van (2010), Familial Longevity Is Associated with Decreased Thyroid Function, Journal of Clinical Endocrinology and Metabolism 95(11): 4979-4984.
- Ruhaak, L.R.; Uh, H.W.; Beekman, M.; Koeleman, C.A.M.; Hokke, C.H.; Westendorp, R.G.J.; Wuhrer, M.; Houwing-Duistermaat, J.J.; Slagboom, P.E. & Deelder, A.M. (2010), Decreased Levels of Bisecting GlcNAc Glycoforms of IgG Are Associated with Human Longevity, PLoS ONE 5(9).
- Callegaro, A.; Meulenbelt, I.; Kloppenburg, M.; Slagboom, P.E. & Houwing-Duistermaat, J.J. (2010), Allele-Sharing Statistics Using Information on Family History, Annals of Human Genetics 74: 547-554.
- Bos, S.D.; Lakenberg, N.; Breggen, R. van der; Houwing-Duistermaat, J.J.; Kloppenburg, M.; Craen, A.J.M. de; Beekman, M.; Meulenbelt, I. & Slagboom, P.E. (2010), A genome-wide linkage scan reveals CD53 as an important regulator of innate TNF-alpha levels, European Journal of Human Genetics 18(8): 953-959.
- Meulenbelt, I.; Bos, S.D.; Kloppenburg, M.; Lakenberg, N.; Houwing-Duistermaat, J.J.; Watt, I.; Craen, A.J. de; Duijn, C.M. van & Slagboom, P.E. (2010), Interleukin-1 Gene Cluster Variants With Innate Cytokine Production Profiles and Osteoarthritis in Subjects From the Genetics, Osteoarthritis and Progression Study, Arthritis and Rheumatism 62(4): 1119-1126.
- Kuningas, M.; Bodegom, D. van; May, L.; Meij, J.J.; Slagboom, P.E. & Westendorp, R.G.J. (2010), Common CFTR gene variants influence body composition and survival in rural Ghana.
- Landt, M.C.T.S.O.; Dolan, C.V.; Rebollo-Mesa, I.; Bartels, M.; Furth, E.F. van; Beijsterveldt, C.E.M. van; Meulenbelt, I.; Slagboom, P.E. & Boomsma, D.I. (2010), Sex differences in sum scores may be hard to interpret: The importance of measurement invariance. (vol 16, pg 415, 2010), Assessment 17(2): 278-278.
- Reiling, E.; Jafar-Mohammadi, B.; van't Riet, E.; Weedon, M.N.; Vliet-Ostaptchouk, J.V. van; Hansen, T.; Saxena, R.; Haeften, T.W. van; Arp, P.A.; , S. das; Nijpels, G.; Groenewoud, M.J.; Hove, E.C. van; Uitterlinden, A.G.; Smit, J.W.A.; Morris, A.D.; Doney, A.S.F.; Palmer, C.N.A.; Guiducci, C.; Hattersley, A.T.; Frayling, T.M.; Pedersen, O.; Slagboom, P.E.; Altshuler, D.M.; Groop, L.; Romijn, J.A.; Maassen, J.A.; Hofker, M.H.; Dekker, J.M.; McCarthy, M.I. & Hart, L.M. 't (2010), Genetic association analysis of LARS2 with type 2 diabetes., Diabetologia 53(1): 103-10.
- Rozing, M.P.; Westendorp, R.G.J.; Craen, A.J.M. de; Frolich, M.; Goeij, M.C.M. de; Heijmans, B.T.; Beekman, M.; Wijsman, C.A.; Mooijaart, S.P.; Blauw, G.J.; Slagboom, P.E.; Heemst, D. van & Leiden Longevity Study Grp (2010), Favorable Glucose Tolerance and Lower Prevalence of Metabolic Syndrome in Offspring without Diabetes Mellitus of Nonagenarian Siblings: The Leiden Longevity Study, Journal of the American Geriatrics Society 58(3): 564-569.
- Yusuf, E.; Bijsterbosch, J.; Slagboom, P.E.; Kroon, H.; Rosendaal, F.R.; Huizinga, T.W. & Kloppenburg, M. (2010), DETERMINANTS OF CLINICAL PROGRESSION OF LOWER EXTREMITY OSTEOARTHRITIS, Osteoarthritis and Cartilage 18: S159S159.
- Bijsterbosch, J.; Bemmel, J.M. van; Watt, I.; Meulenbelt, I.; Rosendaal, F.R.; Huizinga, T.W. & Kloppenburg, M. (2010), CARTILAGE LOSS AND PAIN ARE INDEPENDENT RISK FACTORS IN THE EVOLUTION OF EROSIVE HAND OSTEOARTHRITIS, Osteoarthritis and Cartilage 18: S126S126.
- May, L.; Kuningas, M.; Bodegom, D. van; Meij, H.J.; Frolich, M.; Slagboom, P.E.; Mantovani, A. & Westendorp, R.G.J. (2010), Genetic variation in pentraxin (PTX) 3 gene associates with PTX3 production and fertility in women.
- Hart, L.M. 't; Simonis-Bik, A.M.; Nijpels, G.; Haeften, T.W. van; Schafer, S.A.; Houwing-Duistermaat, J.J.; Boomsma, D.I.; Groenewoud, M.J.; Reiling, E.; Hove, E.C. van; Diamant, M.; Kramer, M.H.H.; Heine, R.J.; Maassen, J.A.; Kirchhoff, K.; Machicao, F.; Haring, H.U.; Slagboom, P.E.; Willemsen, G.; Eekhoff, E.M.; Geus, E.J. de; Dekker, J.M. & Fritsche, A. (2010), Combined risk allele score of eight type 2 diabetes genes is associated with reduced first-phase glucose-stimulated insulin secretion during hyperglycemic clamps.
- Bijsterbosch, J.; Wassenaar, M.J.E.; Cessie, S. le; Slagboom, P.E.; Rosendaal, F.R.; Huizinga, T.W.J. & Kloppenburg, M. (2010), Doyle Index is a valuable additional pain measure in osteoarthritis, Osteoarthritis and Cartilage 18(8): 1046-1050.
- Ruhaak, L.R.; Uh, H.W.; Beekman, M.; Hokke, C.H.; Westendorp, R.G.J.; Houwing-Duistermaat, J.; Wuhrer, M.; Deelder, A.M. & Sagboom, P.E. (2010), Plasma protein N-glycan profiles are associated with calendar age, familial longevity and health., Journal of Proteome Research.
- Willemsen, G.; Geus, E.J.C. de; Bartels, M.; Beijsterveldt, C.E.M.T. van; Brooks, A.I.; Estourgie-van Burk, G.F.; Fugman, D.A.; Hoekstra, C.; Hottenga, J.J.; Kluft, K.; Meijer, P.; Montgomery, G.W.; Rizzu, P.; Sondervan, D.; Smit, A.B.; Spijker, S.; Suchiman, H.E.D.; Tischfield, J.A.; Lehner, T.; Slagboom, P.E. & Boomsma, D.I. (2010), The Netherlands Twin Register Biobank: A Resource for Genetic Epidemiological Studies, Twin Research and Human Genetics 13(3): 231-245.
- Lescai F, Blanche H, Nebel A, Beekman M, Sahbatou M, Flachsbart F, Slagboom E, Schreiber S, Sorbi S, Passarino G & Franceschi C (2009), Human longevity and 11p15.5: a study in 1321 centenarians, European Journal of Human Genetics 17(11): 1515-1519.
- Tobi EW, Lumey L, Talens RP, Kremer D, Putter H, Stein AD, Slagboom PE & Heijmans BT (2009), DNA methylation differences after exposure to prenatal famine are common and timing- and sex-specific, Human Molecular Genetics 18(21): 4046-4053.
- Kerkhof HJM, Jonsdottir I, Meulenbelt I, Stolk L, Valdes AM, Zhai G, Zhu Y, Doherty M, Doherty S, Tsezou A, Gonzalez A, Carr A, Felson DT, Styrkarsdottir U, Slagboom EP, Loughlin J, Rivadeneira F, Hofman A, Pols HAP, Spector TD, Uitterlinden AG & van Meurs JBJ (2009), A genome-wide association study identifies a common variant near the GRP22 gene as a new locus involved in prevalence and progression of osteoarthritis, BONE 44(2): S224S224.
- Sampietro ML, Pons D, de Knijff P, Slagboom PE, Zwinderman AH & Jukema JW (2009), A genome wide association analysis in the GENDER study, Netherlands Heart Journal 17(6): 262-264.
- Evangelou E, Chapman K, Meulenbelt I, Karassa FB, Loughlin J, Carr A, Doherty M, Doherty S, Gomez-Reino JJ & Gonzalez A (2009), Large-Scale Analysis of Association Between GDF5 and FRZB Variants and Osteoarthritis of the Hip, Knee, and Hand, Arthritis and Rheumatism 60(6): 1710-1721.
- Dieguez-Gonzalez R, Calaza M, Shi D, Meulenbelt I, Loughlin J, Tsezou A, Dai J, Malizos KN, Slagboom EP & Kloppenburg M (2009), Testing the druggable endothelial differentiation gene 2 knee osteoarthritis genetic factor for replication in a wide range of sample collections, Annals of the Rheumatic Diseases 68(6): 1017-1021.
- Bos SD, Kloppenburg M, Suchiman E, van Beelen E, Slagboom PE & Meulenbelt I (2009), The role of plasma cytokine levels, CRP and Selenoprotein S gene variation in OA, Osteoarthritis and Cartilage 17(5): 621-626.
- Steegers-Theunissen RP, Borst SA, Kremer D, Lindemans J, Siebel C, Steegers EA, Slagboom E & Heijmans BT (2009), Epigenetic Changes after Periconception Folic Acid Supplementation in Humans, Reproductive Sciences 16(3): 97A97A.
- Rodriguez-Lopez J, Pombo-Suarez M, Loughlin J, Tsezou A, Blanco FJ, Meulenbelt I, Slagboom PE, Valdes AM, Spector TD & Gomez-Reino JJ (2009), Association of a nsSNP in ADAMTS14 to some osteoarthritis phenotypes, Osteoarthritis and Cartilage 17(3): 321-327.
- Vink JM, Smit AB, de Geus EJC, Sullivan P, Willemsen G, Hottenga JJ, Smit JH, Hoogendijk WJ, Zitman FG, Peltonen L, Kaprio J, Pedersen NL, Magnusson PK, Spector TD, Kyvik KO, Morleyis KI, Heath AC, Martin NG, Westendorp RGJ, Slagboom PE, Tiemeier H, Hofman A, Uitterlinden AG, Aulchenko YS, Amin N, van Duijn C, Penninx BW & Boomsma DI (2009), Genome-wide Association Study of Smoking Initiation and Current Smoking, American Journal of Human Genetics 84(3): 367-379.
- Slof-Op 't Landt MCT, van Furth EF, Rebollo-Mesa I, Bartels M, van Beijsterveldt CEM, Slagboom PE, Boomsma DI, Meulenbelt I & Dolan CV (2009), Sex Differences in Sum Scores May Be Hard to Interpret The Importance of Measurement Invariance, Assessment 16(4): 415-423.
- Finken MJJ, Meulenbelt I, Dekker FW, Frolich M, Romijn J, Slagboom E & Wit JM (2009), Adverse body composition in adult life after perinatal glucocorticoid therapy in prematurely born individuals carrying the 363S variant of the N363S polymorphism in the glucocorticoid receptor gene, Hormone Research 72: 426-426.
- Westendorp RGJ, van Heemst D, Rozing MP, Frolich M, Mooijaart SP, Blauw GJ, Beekman M, Heijmans BT, de Craen AJM & Slagboom PE (2009), Nonagenarian Siblings and Their Offspring Display Lower Risk of Mortality and Morbidity than Sporadic Nonagenarians: The Leiden Longevity Study, Journal of the American Geriatrics Society 57(9): 1634-1637.
- Kuningas M, May L, Tamm R, van Bodegom D, van den Biggelaar AHJ, Meij JJ, Frolich M, Ziem JB, Suchiman HED, Metspalu A, Slagboom PE & Westendorp RGJ (2009), Selection for Genetic Variation Inducing Pro-Inflammatory Responses under Adverse Environmental Conditions in a Ghanaian Population, PLoS ONE 4(11): A174A180.
- Kuningas M, Mooijaart SP, Jolles J, Slagboom PE, Westendorp RGJ & van Heemst D (2009), VDR gene variants associate with cognitive function and depressive symptoms in old age, Neurobiology of Aging 30(3): 466-473.
- Houwing-Duistermaat JJ, Callegaro A, Beekman M, Westendorp RG, Slagboom PE & van Houwelingen JC (2009), Weighted statistics for aggregation and linkage analysis of human longevity in selected families: The Leiden Longevity Study, Statistics in Medicine 28(1): 140-151.
- Rozing MP, Westendorp RG, Frölich M, de Craen AJ, Beekman M, Heijmans BT, Mooijaart SP, Blauw GJ, Slagboom PE, van Heemst D & Group OB (2009), Human insulin/IGF-1 and familial longevity at middle age., Aging 1(8): 714-22.
- Reiling E, van Vliet-Ostaptchouk JV, van't Riet E, van Haeften TW, Arp PA, Hansen T, Kremer D, Groenewoud MJ, van Hove EC & Romijn JA (2009), Genetic association analysis of 13 nuclear-encoded mitochondrial candidate genes with type II diabetes mellitus: the DAMAGE study, European Journal of Human Genetics 17(8): 1056-1062.
- Meulenbelt I, Chapman K, Dieguez-Gonzalez R, Shi DQ, Tsezou A, Dai J, Malizos KN, Kloppenburg M, Carr A & Nakajima M (2009), Large replication study and meta-analyses of DVWA as an osteoarthritis susceptibility locus in European and Asian populations, Human Molecular Genetics 18(8): 1518-1523.
- Zhai G, van Meurs JBJ, Livshits G, Meulenbelt I, Valdes AM, Soranzo N, Hart D, Zhang F, Kato BS, Richards JB, Williams FM, Inouye M, Kloppenburg M, Deloukas P, Slagboom E, Uitterlinden A & Spector TD (2009), A genome-wide association study suggests that a locus within the ataxin 2 binding protein 1 gene is associated with hand osteoarthritis: the Treat-OA consortium, Journal of Medical Genetics 46(9): 614-616.
- Sampietro ML, Pons D, de Knijff P, Slagboom PE, Zwinderman A & Jukema JW (2009), A genome wide association analysis in the GENDER study., Netherlands Heart Journal 17(6): 262-4.
- Albers HM, Kurreeman FAS, Stoeken-Rijsbergen G, Brinkman DMC, Kamphuis SSM, van Rossum MAJ, Girschick HJ, Wouters C, Saurenmann RK, Hoppenreijs E, Slagboom P, Houwing-Duistermaat JJ, Verduijn W, Huizinga TWJ, ten Cate R, Toes REM & Schilham MW (2009), Association of the Autoimmunity Locus 4q27 With Juvenile Idiopathic Arthritis, Arthritis and Rheumatism 60(3): 901-904.
- Tobi EW, Lumey LH, Talens RP, Kremer D, Putter H, Stein AD, Slagboom PE & Heijmans BT (2009), DNA methylation differences after exposure to prenatal famine are common and timing- and sex-specific., Human Molecular Genetics 18(21): 4046-53.
- Westendorp RG, van Heemst D, Rozing MP, Frölich M, Mooijaart SP, Blauw GJ, Beekman M, Heijmans BT, de Craen AJ, Slagboom PE & (2009), Nonagenarian siblings and their offspring display lower risk of mortality and morbidity than sporadic nonagenarians: The Leiden Longevity Study., Journal of the American Geriatrics Society 57(9): 1634-7.
- Houwing-Duistermaat JJ, Callegaro A, Beekman M, Westendorp RG, Slagboom PE & van Houwelingen JC (2009), Weighted statistics for aggregation and linkage analysis of human longevity in selected families: the Leiden Longevity Study., Statistics in Medicine 28(1): 140-51.
- Albers HM, Kurreeman FA, Stoeken-Rijsbergen G, Brinkman DM, Kamphuis SS, van Rossum MA, Girschick HJ, Wouters C, Saurenmann RK, Hoppenreijs E, Slagboom P, Houwing-Duistermaat JJ, Verduijn W, Huizinga TW, Ten Cate R, Toes RE & Schilham MW (2009), Association of the autoimmunity locus 4q27 with juvenile idiopathic arthritis., Arthritis and Rheumatism 60(3): 901-4.
- May L, van Bodegom D, Frölich M, van Lieshout L, Slagboom PE, Westendorp RG & Kuningas M (2009), Polymorphisms in TLR4 and TLR2 genes, cytokine production and survival in rural Ghana., European Journal of Human Genetics.
- Kuningas M, May L, Tamm R, van Bodegom D, van den Biggelaar AH, Meij JJ, Frölich M, Ziem JB, Suchiman HE, Metspalu A, Slagboom PE & Westendorp RG (2009), Selection for genetic variation inducing pro-inflammatory responses under adverse environmental conditions in a Ghanaian population., PLoS ONE 4(11): e7795.
- Steegers-Theunissen RP, Obermann-Borst SA, Kremer D, Lindemans J, Siebel C, Steegers EA, Slagboom PE & Heijmans BT (2009), Periconceptional maternal folic acid use of 400 microg per day is related to increased methylation of the IGF2 gene in the very young child., PLoS ONE 4(11): e7845.
- Heijmans BT, Tobi EW, Lumey LH & Slagboom PE (2009), The epigenome: archive of the prenatal environment., Epigenetics 4(8): 526-31.
- null
- Botha-Scheepers S, Riyazi N, Watt I, Rosendaal FR, Slagboom E, Bellamy N, Breedveld FC & Kloppenburg M (2009), Progression of hand osteoarthritis over 2 years: a clinical and radiological follow-up study., Annals of the Rheumatic Diseases 68(8): 1260-4.
- Heijmans BT, Tobi EW, Lumey LH & Slagboom PE (2009), The epigenome Archive of the prenatal environment, Epigenetics 4(8): 526-531.
- Reiling E, van Vliet-Ostaptchouk JV, van 't Riet E, van Haeften TW, Arp PA, Hansen T, Kremer D, Groenewoud MJ, van Hove EC, Romijn JA, Smit JW, Nijpels G, Heine RJ, Uitterlinden AG, Pedersen O, Slagboom PE, Maassen JA, Hofker MH, 't Hart LM & Dekker JM (2009), Genetic association analysis of 13 nuclear-encoded mitochondrial candidate genes with type II diabetes mellitus: the DAMAGE study., European Journal of Human Genetics 17(8): 1056-62.
- Uh HW, Beekman M, Slagboom PE & Houwing-Duistermaat JJ (2009), Testing for genetic association using family data: incorporating phenotypic information of un-genotyped relatives, Annals of Human Genetics 73: 662-662.
- Middeldorp CM, Sullivan PF, Wray NR, Hottenga JJ, de Geus EJC, van den Berg M, Montgomery GW, Coventry WL, Statham DJ, Andrews G, Slagboom PE, Boomsma DI & Martin NG (2009), Suggestive Linkage on Chromosome 2, 8, and 17 for Lifetime Major Depression.
- Kettunen J, Perola M, Martin NG, Cornes BK, Wilson SG, Montgomery GW, Benyamin B, Harris JR, Boomsma D, Willemsen G, Hottenga JJ, Slagboom PE, Christensen K, Kyvik KO, Sorensen TIA, Pedersen NL, Magnusson PKE, Andrew T, Spector TD, Widen E, Silventoinen K, Kaprio J, Palotie A & Peltonen L (2009), Multicenter dizygotic twin cohort study confirms two linkage susceptibility loci for body mass index at 3q29 and 7q36 and identifies three further potential novel loci, International Journal of Obesity 33(11): 1235-1242.
- Meulenbelt I, Chapman K, Dieguez-Gonzalez R, Shi D, Tsezou A, Dai J, Malizos KN, Kloppenburg M, Carr A, Nakajima M, van der Breggen R, Lakenberg N, Gomez-Reino JJ, Jiang Q, Ikegawa S, Gonzalez A, Loughlin J & Slagboom EP (2009), Large replication study and meta-analyses of DVWA as an osteoarthritis susceptibility locus in European and Asian populations., Human Molecular Genetics 18(8): 1518-23.
- Bos SD, Kloppenburg M, Suchiman E, van Beelen E, Slagboom PE & Meulenbelt I (2009), The role of plasma cytokine levels, CRP and Selenoprotein S gene variation in OA., Osteoarthritis and Cartilage 17(5): 621-6.
- Botha-Scheepers S, Riyazi N, Watt I, Rosendaal FR, Slagboom E, Bellamy N, Breedveld FC & Kloppenburg M (2009), Progression of hand osteoarthritis over 2 years: a clinical and radiological follow-up study, Annals of the Rheumatic Diseases 68(8): 1260-1264.
- Colas F, Meulenbelt I, Houwing-Duistermaat JJ, Kloppenburg M, Watt I, van Rooden SM, Visser M, Marinus J, van Hilten JJ, Slagboom PE & Kok JN (2008), Reliability of Cluster Results for Different Types of Time Adjustments in Complex Disease Research, 2008 30TH ANNUAL INTERNATIONAL CONFERENCE OF THE IEEE ENGINEERING IN MEDICINE AND BIOLOGY SOCIETY, VOLS 1-8: 4601-4604.
- Colas F, Meulenbelt I, Houwing-Duistermaat JJ, Kloppenburg M, Watt I, van Rooden SA, Visser M, Marinus J, Cannon EO, Bender A, van Hilten JJ, Slagboom PE & Kok JN (2008), A Scenario Implementation in R for SubtypeDiscovery Examplified on Chemoinformatics Data, LEVERAGING APPLICATIONS OF FORMAL METHODS, VERIFICATION AND VALIDATION, PROCEEDINGS 17: 669-683.
- Colas F, Meulenbelt I, Houwing-Duistermaat JJ, Slagboom PE & Kok JN (2008), A comparison of two methods for finding groups using heat maps and model based clustering, APPLICATIONS AND INNOVATIONS IN INTELLIGENT SYSTEMS XV: 119-131.
- Heijmans BT, Tobi EW, Stein AD, Putter H, Blauw GJ, Susser ES, Slagboom PE & Lumey LH (2008), Persistent epigenetic differences associated with prenatal exposure to famine in humans, Proceedings of the National Academy of Sciences 105(44).
- Uh HW, Beekman M, Slagboom PE & Duistermaat JJH (2008), Testing for genetic association in an affected sibling pair - control design taking into account phenotypic information of relatives, Genetic Epidemiology 32(7).
- Trompet, S.; Craen, A.J.M. de; Slagboom, P.; Shepherd, J.; Blauw, G.J.; Murphy, M.B.; Bollen, E.L.E.M.; Buckley, B.M.; Ford, I.; Gaw, A.; Macfarlane, P.W.; Packard, C.J.; Stott, D.J.; Westendorp, R.G.J.; Jukema, J.W. & PROSPER Grp (2008), Lymphotoxin-alpha C804A polymorphism is a risk factor for stroke. The PROSPER study, Experimental Gerontology 43(8).
- Slagboom E & Meulenbelt I (2008), Genetics of osteoarthritis: early developmental clues to an old disease, Nature Clinical Practice Rheumatology 4(11).
- Wray NR, Middeldorp CM, Birley AJ, Gordon SD, Sullivan PF, Visscher PM, Nyholt DR, Willemsen G, de Geus EJC, Slagboom PE, Montgomery GW, Martin NG & Boomsma DI (2008), Genome-wide linkage analysis of multiple measures of neuroticism of 2 large cohorts from Australia and the Netherlands, Archives of General Psychiatry 65(6).
- 't Landt MCTSO, Bartels M, van Furth EF, van Beijsterveldt CEM, Meulenbelt I, Slagboom PE & Boomsma DI (2008), Genetic influences on disordered eating behaviour are largely independent of body mass index.
- Trompet S, de Craen AJM, Slagboom P, Shepherd J, Blauw GJ, Murphy MB, Bollen ELEM, Buckley BM, Ford I, Gaw A, Macfarlane PW, Packard CJ, Stott DJ, Jukema JW & Westendorp RGJ (2008), Genetic variation in the interleukin-1 beta-converting enzyme associates with cognitive function. The PROSPER study, Brain 131.
- Middeldorp CM, Hottenga JJ, Slagboom PE, Sullivan PF, de Geus EJC, Posthuma D, Willemsen G & Boomsma DI (2008), Linkage on chromosome 14 in a genome-wide linkage study of a broad anxiety phenotype, Molecular Psychiatry 13(1).
- Macgregor S, Hottenga JJ, Lind PA, Suchiman HED, Willemsen G, Slagboom PE, Montgomery GW, Martin NG, Visscher PM & Boomsma DI (2008), Vitamin D Receptor Gene Polymorphisms Have Negligible Effect on Human Height, Twin Research and Human Genetics 11(5).
- Bos SD, Slagboom PE & Meulenbelt I (2008), New insights into osteoarthritis: early developmental features of an ageing-related disease, Current Opinion in Rheumatology 20(5).
- Shifman S, Bhomra A, Smiley S, Wray NR, James MR, Martin NG, Hettema JM, An SS, Neale MC, Van den Oord EJCG, Kendler KS, Chen X, Boomsma DI, Middeldorp CM, Hottenga JJ, Slagboom PE & Flint J (2008), A whole genome association study of neuroticism using DNA pooling, Molecular Psychiatry 13(3).
- Ghidey W, Stijnen T, Houwing-Duistermaat J, Heijmans B, Beekman M, Westendorp R, Slagboom E & van Houwelingen HC (2008), Predicting a binary outcome using SNPs: a case study on prediction of longevity, Genetic Epidemiology 32(7).
- Passtoors WM, Beekman M, Gunn D, Boer JM, Heijmans BT, Westendorp RGJ, Zwaan BJ & Slagboom PE (2008), Genomic studies in ageing research: the need to integrate genetic and gene expression approaches, Journal of Internal Medicine 263(2).
- Ghidey W, Stijnen T, Houwing-Duistermaat JJ, Heijmans BT, Beekman M, Westendorp RGJ, Slagboom PE & van Houwelingen HC (2008), Prediction models for SNP data, Annals of Human Genetics 72.
- Botha-Scheepers S, Watt I, Slagboom E, de Craen AJM, Meulenbelt I, Rosendaal FR, Breedveld FC, Huizinga TWJ & Kloppenburg M (2008), Innate production of tumour necrosis factor alpha and interleukin 10 is associated with radiological progression of knee osteoarthritis, Annals of the Rheumatic Diseases 67(8).
- Chapman K, Takahashi A, Meulenbelt I, Watson C, Rodriguez-Lopez J, Egli R, Tsezou A, Malizos KN, Kloppenburg M, Shi DQ, Southam L, van der Breggen R, Donn R, Qin JH, Doherty M, Slagboom PE, Wallis G, Kamatani N, Jiang Q, Gonzalez A, Loughlin J & Ikegawa S (2008), A meta-analysis of European and Asian cohorts reveals a global role of a functional SNP in the 5 ' UTR of GDF5 with osteoarthritis susceptibility, Human Molecular Genetics 17(10).
- Kuningas, M.; Mooijaart, S.P.; Heemst, D. van; Zwaan, B.J.; Slagboom, P.E. & Westendorp, R.G.J. (2008), Genes encoding longevity: from model organisms to humans, Aging Cell 7(2).
- Meulenbelt I, Min JL, Bos S, Riyazi N, Houwing-Duistermaat JJ, van der Wijk HJ, Kroon HM, Nakajima M, Ikegawa S, Uitterlinden AG, van Meurs JBJ, van der Deure WM, Visser TJ, Seymour AB, Lakenberg N, van der Breggen R, Kremer D, van Duijn CM, Kloppenburg M, Loughlin J & Slagboom PE (2008), Identification of DIO2 as a new susceptibility locus for symptomatic osteoarthritis, Human Molecular Genetics 17(12).
- Riyazi N, Rosendaal FR, Slagboom E, Kroon HM, Breedveld FC & Kloppenburg M (2008), Risk factors in familial osteoarthritis: the GARP sibling study, Osteoarthritis and Cartilage 16(6).
- Bos SD, Suchiman HED, Kloppenburg M, Houwing-Duistermaat JJ, le Graverand MPH, Seymour AB, Kroon HM, Slagboom PE & Meulenbelt I (2008), Allelic variation at the C-reactive protein gene associates to both hand osteoarthritis severity and serum high sensitive C-reactive protein levels in the GARP study, Annals of the Rheumatic Diseases 67(6).
- Kurreeman FAS, Verpoort KN, Ioan-Facsinay A, Schonkeren JJM, Uh HW, Slagboom E, Westendorp RG, Toes REM & Huizinga TWJ (2007), The association between IL10 and joint destruction in RA can be attributed to enhanced autoantibody responses, Annals of the Rheumatic Diseases 66.
- Margarita, C.T.; Landt, S.O.T.; Bartels, M.; Furth, E.F. van; Meulenbelt, I.; Slagboom, E. & Boomsma, D.I. (2007), Genetic influences on disordered eating behavior are largely independent of BMI, Behavior Genetics 37(6): 794-794.
- Botha-Scheepers SA, Watt I, Slagboom E, Meulenbelt I, Rosendaal FR, Breedveld FC & Kloppenburg M (2007), Influence of familial factors on radiologic disease progression over two years in siblings with osteoarthritis at multiple sites: A prospective longitudinal cohort study, Arthritis and Rheumatism 57(4).
- Thabet MM, Wesoly J, Slagboom PE, Toes REM & Huizinga TWJ (2007), FCRL3 promoter 169 CC homozygosity is associated with susceptibility to rheumatoid arthritis in Dutch Caucasians, Annals of the Rheumatic Diseases 66(6).
- Botha-Scheepers S, Riyazi N, Watt I, Rosendaal FR, Slagboom E, Bellamy N, Breedveld FC & Kloppenburg M (2007), Progression of hand osteoarthritis over two years: A clinical and radiological follow-up study, Annals of the Rheumatic Diseases 66.
- Kurreeman FAS, Verpoort KN, Ioan-Facsinay A, Schonkeren JJM, Uh H, Slagboom E, Westendorp R, Toes REM & Huizinga TWJ (2007), The association between IL10 and joint destruction in RA can be attributed to enhanced autoantibody responses, Annals of the Rheumatic Diseases 66.
- Bakaysa SL, Mucci LA, Slagboom PE, Boomsma DI, McClearn GE, Johansson B & Pedersen NL (2007), Telomere length predicts survival independent of genetic influences, Aging Cell 6(6).
- Mooijaart, S.P.; Kuningas, M.; Westendorp, R.G.J.; Houwing-Duistermaat, J.J.; Slagboom, P.E.; Rensen, P.C.N. & Heemst, D. van (2007), Liver X receptor alpha associates with human life span, The Journals of Gerontology, Series A: Biological Sciences and Medical Sciences 62(4).
- Trompet S, Pons D, De Craen AJM, Slagboom P, Shepherd J, Blauw GJ, Murphy MB, Cobbe SM, Bollen ELEM, Buckley BM, Ford I, Hyland M, Gaw A, Macfarlane PW, Packard CJ, Norrie J, Perry IJ, Stott DJ, Sweeney BJ, Twomey C, Westendorp RGJ & Jukema JW (2007), Genetic variation in the interleukin-10 gene promoter and risk of coronary and cerebrovascular events - The PROSPER study, Annals of the New York Academy of Sciences 1100.
- Kuningas, M.; Rijk, R.H. de; Westendorp, R.G.J.; Jolles, J.; Slagboom, P.E. & Heemst, D. van (2007), Mental performance in old age dependent on cortisol and genetic variance in the mineralocorticoid and glucocorticoid receptors, Neuropsychopharmacology 32(6).
- Middeldorp CM, de Geus EJC, Beem AL, Lakenberg N, Hottenga JJ, Slagboom PE & Boomsma DI (2007), Family based association analyses between the serotonin transporter gene polymorphism (5-HTTLPR) and neuroticism, anxiety and depression, Behavior Genetics 37(2).
- Heijmans BT, Kremer D, Tobi EW, Boomsma DI & Slagboom PE (2007), Heritable rather than age-related environmental and stochastic factors dominate variation in DNA methylation of the human IGF2/H19 locus, Human Molecular Genetics 16(5).
- Loughlin J, Meulenbelt I, Min J, Mustafa Z, Sinsheimer JS, Carr A & Slagboom PE (2007), Genetic association analysis of RHOB and TXNDC3 in osteoarthritis, American Journal of Human Genetics 80(2).
- Botha-Scheepers S, Watt I, Slagboom E, Craen AJM, Meulenbelt I, Rosendaal F, Breedveld FC, Huizinga TWJ & Kloppenburg M (2007), Innate production of tumor necrosis factor-alpha and interleukin-10 is associated with radiological progression of knee osteoarthritis, Annals of the Rheumatic Diseases 66.
- Trompet, S.; Pons, D.; Craen, A.J.M. de; Slagboom, P.; Shepherd, J.; Blauw, G.J.; Murphy, M.B.; Cobbe, S.M.; Bollen, E.L.E.M.; Buckley, B.M.; Ford, I.; Hyland, M.; Gaw, A.; Macfarlane, P.W.; Packard, C.J.; Norrie, J.; Perry, I.J.; Stott, D.J.; Sweeney, B.J.; Twomey, C.; Westendorp, R.G.J.; Jukema, J.W.; PROSPER Grp; Rattan, S.I.S. & Akman, S. (2007), Genetic variation in the interleukin-10 gene promoter and risk of coronary and cerebrovascular events: the PROSPER study., Annals of the New York Academy of Sciences 1100: 189-98.
- Hottenga JJ, Suchiman E, Willemsen G, Slagboom E & Boomsma DI (2007), The vitamin D receptor gene is not strongly associated with stature: Results from the Netherlands twin register, Behavior Genetics 37(6): 763-763.
- Sahiratmadja E, Wieringa FT, van Crevel R, de Visser AW, Adnan I, Alisjahbana B, Slagboom E, Marzuki S, Ottenhoff THM, van de Vosse E & Marx JJA (2007), Iron deficiency and NRAMP1 polymorphisms (INT4, D543N and 3/UTR) do not contribute to severity of anaemia in tuberculosis in the Indonesian population, British Journal of Nutrition 98(4).
- Houwing-Duistermaat JJ, Callegaro A, Beekman M, Westendorp RGJ, Slagboom E & van Houwelingen JC (2007), A score statistic for linkage analysis of censored outcomes applied to a candidate region at chromosome 4 for human longevity, Genetic Epidemiology 31(5).
- Lambert JC, Ferreira S, Gussekloo J, Christiansen L, Brysbaert G, Slagboom E, Cottel D, Petit T, Hauw J, DeKosky ST, Richard F, Berr C, Lendon C, Kamboh MI, Mann D, Christensen K, Westendorp R & Amouyel P (2007), Evidence for the association of the S100 beta gene with low cognitive performance and dementia in the elderly, Molecular Psychiatry 12(9).
- Slagboom PE, Heijmans BT, Beekman M & Meulenbelt I (2007), Molecular epidemiology, candidate genes versus genome-wide scans, Genes and Nutrition 2(1).
- Min JL, Meulenbelt I, Kloppenburg M, van Duijn CM & Slagboom PE (2007), Mutation analysis of candidate genes within the 2q33.3 linkage area for familial early-onset generalised osteoarthritis, European Journal of Human Genetics 15(7).
- Pons D, Monraats PS, de Vries FR, de Maat MP, Zwinderman AH, de Winter RJ, Doevendans PAFM, Tio RA, Frants RR, Heijmans BT, Slagboom PE, van der Laarse A, van der Wall EE & Jukema JW (2007), Involvement of EPIgenetic variation in restenosis after PCI, Journal of the American College of Cardiology 49(9).
- Houwing-Duistermaat JJ, Helmer Q, Heijmans BT, Beekman M & Slagboom PE (2007), Selection of informative SNPs for sibling pair linkage analysis from large SNP arrays, Genetic Epidemiology 31(6).
- Ali S, Vollaard AM, Kremer D, de Visser AW, Martina CAE, Widjaja S, Surjadi C, Slagboom E, van de Vosse E & Van Dissel JT (2007), Polymorphisms in proinflammatory genes and susceptibility to typhoid fever and paratyphoid fever, Journal of Interferon and Cytokine Research 27(4).
- Finken MJJ, Meulenbelt I, Dekker FW, Frolich M, Romijn JA, Slagboom PE & Wit JM (2007), The 23K variant of the R23K polymorphism in the glucocorticoid receptor gene protects against postnatal growth failure and insulin resistance after preterm birth, Journal of Clinical Endocrinology and Metabolism 92(12).
- Alizadeh BZ, Njajou OT, Hazes JMW, Hofman A, Slagboom PE, Pols HAP & van Duijn CM (2007), The H63D variant in the HFE gene predisposes to arthralgia, chondrocalcinosis and osteoarthritis, Annals of the Rheumatic Diseases 66(11).
- Kuningas, M.; Magi, R.; Westendorp, R.G.J.; Slagboom, P.E.; Remm, M. & Heemst, D. van (2007), Haplotypes in the human Foxo1a and Foxo3a genes; impact on disease and mortality at old age, European Journal of Human Genetics 15(3).
- Meulenbelt I, Kloppenburg M, Kroon HM, Houwing-Duistermaat JJ, Garnero P, Hellio-Le Graverand MP, DeGroot J & Slagboom PE (2007), Clusters of biochemical markers are associated with radiographic subtypes of osteoarthritis (OA) in subject with familial OA at multiple sites. The GARP study, Osteoarthritis and Cartilage 15(4).
- Min JL, Meulenbelt I, Riyazi N, Putter H, Seymour A, Lakenberg N, Van Duijn C, Kloppenburg M & Slagboom E (2006), Genetic linkage analysis of osteoarthritis at multiple joint sites in Dutch sibpairs, Annals of the Rheumatic Diseases 65: 75-75.
- Pons D, Monraats PS, de Vries FR, Zwinderman AH, de Maat MPM, Slagboom PE, Agema WRR, Doevendans PAFM, de Winter RJ, Tio RA, Waltenberger J, Frants RR, van der Laarse A, van der Wall EE & Jukema JW (2006), Different genetic make-up of the anti-inflammatory II10-gene contributes to the development of restenosis after PCI, Journal of the American College of Cardiology 47(4): 317A-317A.
- Heijmans BT, Beekman M, Houwing-Duistermaat JJ, Cobain MR, Powell J, Blauw GJ, van der Ouderaa F, Westendorp RGJ & Slagboom PE (2006), Lipoprotein particle profiles mark familial and sporadic human longevity, PLoS Medicine 3(12): 2317-2323.
- Meulenbelt I, Kloppenburg M, Houwing-Duistermaat JJ, Garnero P, Le Graverand MH, DeGroot J & Slagboom PE (2006), Biochemical markers are associated with radiographic subtypes of osteoarthritis (OA) in subject with familial oa at multiple sites. The GARP study, Annals of the Rheumatic Diseases 65: 589-589.
- Kuningas, M.; Mooijaart, S.P.; Slagboom, P.E.; Westendorp, R.G.J. & Heemst, D. van (2006), Genetic variants in the glucocorticoid receptor gene (NR3C1) and cardiovascular disease risk. The Leiden 85-plus Study, Biogerontology 7(4).
- Mooijaart, S.P.; Berbee, J.F.P.; Heemst, D. van; Havekes, L.M.; Craen, A.J.M. de; Slagboom, P.E.; Rensen, P.C.N. & Westendorp, R.G.J. (2006), ApoE plasma levels and risk of cardiovascular mortality in old age, PLoS Medicine 3(6): 874-883.
- Botha-Scheepers S, Watt I, Slagboom E, de Craen T, Meulenbelt I, Rosendaal FR, Breedveld FC, Huizinga TWJ & Kloppenburg M (2006), Innate production of tumor necrosis factor-alpha and interleukin-10 upon lipopolysaccharide stimulation are associated with radiological progression of knee osteoarthritis., Arthritis and Rheumatism 54(9).
- Min J, Meulenbelt I & Slagboom E (2006), Replication in genetic association studies: comment on the editorial by Spector et al, Arthritis and Rheumatism 54(9).
- Min JL, Lakenberg N, Bakker-Verweij M, Suchiman E, Boomsma DI, Slagboom PE & Meulenbelt I (2006), High microsatellite and SNP genotyping success rates established in a large number of genomic DNA samples extracted from mouth swabs and genotypes, Twin Research and Human Genetics 9(4).
- Valle A, O'Connor DT, Taylor P, Zhu G, Montgomery GW, Slagboom PE, Martin NG & Whitfield JB (2006), Butyrylcholinesterase: Association with the metabolic syndrome and identification of 2 gene loci affecting activity, Clinical Chemistry 52(6).
- Beekman M, Blauw GJ, Houwing-Duistermaat JJ, Brandt BW, Westendorp RGJ & Slagboom PE (2006), Chromosome 4q25, microsomal transfer protein gene, and human longevity: Novel data and a meta-analysis of association studies, Journals of Gerontology, Series A 61(4).
- Boomsma DI, Cacioppo JT, Slagboom PE & Posthuma D (2006), Genetic linkage and association analysis for loneliness in Dutch twin and sibling pairs points to a region on chromosome 12q23-24, Behavior Genetics 36(1).
- Beem AL, de Geus EJC, Hottenga JJ, Sullivan PF, Willemsen G, Slagboom PE & Boomsma DI (2006), Combined linkage and association analyses of the 124-bp allele of marker D2S2944 with anxiety, depression, neuroticism and major depression, Behavior Genetics 36(1).
- Posthuma D, Visscher PM, Willemsen G, Zhu G, Martin NG, Slagboom PE, de Geus EJC & Boomsma DI (2006), Replicated linkage for eye color on 15q using comparative ratings of sibling pairs, Behavior Genetics 36(1).
- Wessels JAM, de Vries-Bouwstra JK, Heijmans BT, Slagboom PE, Goekoop-Ruiterman YPM, Allaart CF, Kerstens PJSM, van Zeben D, Breedveld FC, Dijkmans BAC, Huizinga TWJ & Guchelaar HJ (2006), Efficacy and toxicity of methotrexate in early rheumatoid arthritis are associated with single-nucleotide polymorphisms in genes coding for folate pathway enzymes, Arthritis and Rheumatism 54(4).
- Dahaghin S, Alizadeh B, Bierma-Zeinstra S, Koes B, Slagboom P, Pols H, Van Duijn C, Njajou O & Hazes J (2006), Should patients with osteoarthritis of the metacarpophalangeal joints be screened for hereditary hemochromatosis gene (HFE) mutations?, Annals of the Rheumatic Diseases 65: 228-228.
- Kuningas, M.; Slagboom, P.E.; Westendorp, R.G.J. & Heemst, D. van (2006), Impact of genetic variations in the WRN gene on age related pathologies and mortality, Mechanisms of Ageing and Development 127(3).
- Meulenbelt I, Kloppenburg M, Kroon HM, Houwing-Duistermaat JJ, Garnero P, Le Graverand MPH, DeGroot J & Slagboom PE (2006), Urinary CTX-II levels are associated with radiographic subtypes of osteoarthritis in hip, knee, hand, and facet joints in subject with familial osteoarthritis at multiple sites: the GARP study, Annals of the Rheumatic Diseases 65(3).
- Min JL, Meulenbelt I, Riyazi N, Kloppenburg M, Houwing-Duistermaat JJ, Seymour AB, van Duijn CM & Slagboom PE (2006), Association of matrilin-3 polymorphisms with spinal disc degeneration and osteoarthritis of the first carpometacarpal joint of the hand, Annals of the Rheumatic Diseases 65(8).
- Botha-Scheepers S, Riyazi N, Kroon HM, Scharloo M, Houwing-Duistermaat JJ, Slagboom E, Rosendaal FR, Breedveld FC & Kloppenburg M (2006), Activity limitations in the lower extremities in patients with osteoarthritis: the modifying effects of illness perceptions and mental health, Osteoarthritis and Cartilage 14(11).
- Meulenbelt I, Min JL, van Duijn CM, Kloppenburg M, Breedveld FC & Slagboom PE (2006), Strong linkage on 2q33.3 to familial early-onset generalized osteoarthritis and a consideration of two positional candidate genes, European Journal of Human Genetics 14(12).
- Schoenmaker M, de Craen AJM, de Meijer PHEM, Beekman M, Blauw GJ, Slagboom PE & Westendorp RGJ (2006), Evidence of genetic enrichment for exceptional survival using a family approach: the Leiden Longevity Study, European Journal of Human Genetics 14(1).
- Riyazi N, Rosendaal FR, Slagboom E, Breedveld FC & Kloppenburg M (2005), Risk factors in familial osteoarthritis. The GARP Sibling Study, Annals of the Rheumatic Diseases 64: 67-67.
- Monraats PS, Sewgobind VD, de Vries FR, Zwinderman AH, de Maat MP, Agema WR, Slagboom EP, Doevendans PA, de Winter R, Tio R, Waltenberger J, Frants RR, van der Laarse A, Vandewall E & Jukema JW (2005), MMP9, an important mediator of vascular remodelling, and risk of restenosis after percutaneous coronary intervention, Circulation 112(17): U166-U166.
- Monraats PS, de Vries FR, Slagboom EP, Zwinderman AH, de Maat MP, Agema WR, Hart LMT, de Winter R, Doevendans PA, Waltenberger J, Frants RR, van der Laarse A, Vandewall E & Jukema JW (2005), Inflammation and apoptosis genes and the risk of restenosis after percutaneous coronary intervention, Circulation 112(17): U57-U57.
- Vink JM, Willemsen G, Posthuma D, Slagboom PE, Chen X, Neale M, Kendler K & Boonasma DL (2005), Genetics of smoking and nicotine dependence, Nicotine and Tobacco Research 7(4): 655-656.
- Boomsma DI, Beem AL, Willemsen G, Hottenga JJ, de Geus EJC, Middeldor CM, Sullivan P, Suchiman E, Lakenberg N & Slagboom PE (2005), Genetic association tests of RGS genes on chromosome 1q for depression and correlated traits in the Netherlands Twin-family Study of Anxious Depression (NETSAD), Behavior Genetics 35(6): 794-795.
- Posthuma D, Gosso F, Luciano M, de Geus EJC, Wright MJ, Montgomery GW, van Belzen M, Heutink P, Slagboom PE, Boomsma DI & Martin NG (2005), Gene finding for intelligence, Behavior Genetics 35(6): 817-818.
- Slof-Op 't Landt MCT, van Furth EF, Meulenbelt I, Slagboom RE, Bartels M, Boomsma DI & Bulik CM (2005), Eating disorders: From twin studies to candidate genes and beyond, Twin Research and Human Genetics 8(5).
- Botha-Scheepers SA, Watt I, Rosendaal FR, Breedveld FC, Slagboom E & Kloppenburg M (2005), Familial aggregation of radiological progression in siblings with symptomatic osteoarthritis at multiple sites: The GARP study, Arthritis and Rheumatism 52(9).
- Heijmans BT, Beekman M, Putter H, Lakenberg N, van der Wijk HJ, Whitfield JB, Posthuma D, Pedersen NL, Martin NG, Boomsma DI & Slagboom PE (2005), Meta-analysis of four new genome scans for lipid parameters and analysis of positional candidates in positive linkage regions, European Journal of Human Genetics 13(10).
- Mooijaart, S.P.; Brandt, B.W.; Baldal, E.A.; Pijpe, J.; Kuningas, M.; Beekman, M.; Zwaan, B.J.; Slagboom, P.E.; Westendorp, R.G.J. & Heemst, D. van (2005), C-elegans DAF-12, nuclear hormone receptors and human longevity and disease at old age, Ageing Research Reviews 4(3).
- Wesoly J, Toes REM, Slagboom PE & Huizinga TWJ (2005), RUNX1 intronic SNP is not associated with rheumatoid arthritis susceptibility in Dutch Caucasians, Rheumatology 44(9).
- Riyazi N, Botha-Scheepers SA, Houwing-Duistermaat JJ, Kroon HM, Rosendaal FR, Slagboom E, Breedveld FC & Kloppenburg M (2005), Why is there a discrepancy between disease and disability in osteoarthritis in the hands?, Annals of the Rheumatic Diseases 64.
- Botha-Scheepers SA, Kroon HM, Slagboom E, Rosendaal FR, Breedveld FC & Klopppenburg M (2005), The natural history and determinants of lower extremity functioning over two years in osteoarthritis, Annals of the Rheumatic Diseases 64.
- Posthuma D, Meulenbelt I, de Craen AJM, de Geus EJC, Slagboom PE, Boomsma DI & Westendorp RGJ (2005), Human cytokine response to ex vivo amyloid-beta stimulation is mediated by genetic factors, Twin Research and Human Genetics 8(2).
- Riyazi N, Slagboom E, de Craen AJM, Meulenbelt I, Houwing-Duistermaat JJ, Kroon HM, van Schaardenburg D, Rosendaal FR, Breedveld FC, Huizinga TWJ & Kloppenburg M (2005), Association of the risk of osteoarthritis with high innate production of interleukin-1 beta and low innate production of interleukin-10 ex vivo, upon lipopolysaccharide stimulation, Arthritis and Rheumatism 52(5).
- Alizadeh BZ, Njajou OT, Bijkerk C, Meulenbelt I, De Wildt SC, Hofman A, Pols HAP, Slagboom PE & van Duijn CM (2005), Evidence for a role of the genomic region of the gene encoding for the alpha 1 chain of type IX collagen (COL9A1) in hip osteoarthritis - A population-based study, Arthritis and Rheumatism 52(5).
- Min JL, Meulenbelt I, Riyazi N, Kloppenburg M, Houwing-Duistermaat JJ, Seymour AB, Pols HA, van Duijn CM & Slagboom PE (2005), Association of the Frizzled-related protein gene with symptomatic osteoarthritis at multiple sites, Arthritis and Rheumatism 52(4).
- Heemst, D. van; Beekman, M.; Mooijaart, S.P.; Heijmans, B.T.; Brandt, B.W.; Zwaan, B.J.; Slagboom, P.E. & Westendorp, R.G.J. (2005), Reduced insulin/IGF-1 signalling and human longevity, Aging Cell 4(2).
- Riyazi N, Meulenbelt I, Kroon HM, Ronday KH, le Graverand MPH, Rosendaal FR, Breedveld FC, Slagboom PE & Kloppenburg M (2005), Evidence for familial aggregation of hand, hip, and spine but not knee osteoarthritis in siblings with multiple joint involvement: the GARP study, Annals of the Rheumatic Diseases 64(3).
- Leroi AM, Bartke A, De Benedictis G, Franceschi C, Gartner A, Gonos E, Feder ME, Kivisild T, Lee S, Kartal-Ozer N, Schumacher M, Sikora E, Slagboom E, Tatar M, Yashin AI, Vijg J & Zwaan B (2005), What evidence is there for the existence of individual genes with antagonistic pleiotropic effects?, Mechanisms of Ageing and Development 126(3).
- Meulenbelt I, Slagboom PE & van Duijn CM (2005), Accuracy of haplotype association studies is enhanced by increasing number of polymorphic loci examined: comment on the article by Meulenbelt et al - Reply, Arthritis and Rheumatism 52(2).
- Heemst, D. van; Mooijaart, S.P.; Beekman, M.; Schreuder, J.; Craen, A.J.M. de; Brandt, B.W.; Slagboom, P.E.; Westendorp, R.G.J. & Long Life study grp (2005), Variation in the human TP53 gene affects old age survival and cancer mortality, Experimental Gerontology 40(1-2).
- de Geus EJC, Posthuma D, Kupper N, van den Berg M, Willemsen G, Beem AL, Slagboom PE & Boomsma DI (2005), A whole-genome scan for 24-hour respiration rate: A major locus at 10q26 influences respiration during sleep, American Journal of Human Genetics 76(1).
- Brandt BW, Zwaan BJ, Beekman M, Westendorp RG & Slagboom PE (2005), Shuttling between species for pathways of lifespan regulation: a central role for the vitellogenin gene family?, BioEssays 27(3): 339-46.
- Mooijaart SP, Brandt BW, Baldal EA, Pijpe J, Kuningas M, Beekman M, Zwaan BJ, Slagboom PE, Westendorp RG & van Heemst D (2005), C. elegans DAF-12, Nuclear Hormone Receptors and human longevity and disease at old age., Ageing Research Reviews 4(3): 351-71.
- Riyazi N, Slagboom E, de Craen AJ, Meulenbelt I, Houwing-Duistermaat JJ, Kroon HM, van Schaardenburg D, Rosendaal FR, Breedveld FC, Huizinga TW & Kloppenburg M (2005), Association of the risk of osteoarthritis with high innate production of interleukin-1beta and low innate production of interleukin-10 ex vivo, upon lipopolysaccharide stimulation., Arthritis and Rheumatism 52(5): 1443-50.
- Leroi AM, Bartke A, De Benedictis G, Franceschi C, Gartner A, Gonos ES, Fedei ME, Kivisild T, Lee S, Kartaf-Ozer N, Schumacher M, Sikora E, Slagboom E, Tatar M, Yashin AI, Vijg J & Zwaan B (2005), What evidence is there for the existence of individual genes with antagonistic pleiotropic effects? (vol 126, pg 421, 2005), Mechanisms of Ageing and Development 126(8): 906-906.
- Legraverand MPH, Pickering E, Redifer P, Totterman S, Tamez J, Slagboom E, Kornaat P, Riyazi N, Sheepers S & Kloppenburg M (2005), The prevalence of bone marrow edema in sibling pairs with familial osteoarthritis at multiple sites. The GARP study., Arthritis and Rheumatism 52(9): S69-S70.
- Posthuma D, Luciano M, de Geus EJC, Wright MJ, Slagboom PE, Montgomery GW, Boomsma DI & Martin NG (2005), A genomewide scan for intelligence identifies quantitative trait loci on 2q and 6p, American Journal of Human Genetics 77(2).
- Brandt BW, Zwaan BJ, Beekman M, Westendorp RGJ & Slagboom PE (2005), Shuttling between species for pathways of lifespan regulation: a central role for the vitellogenin gene family?, BioEssays 27(3).
- Meulenbelt I, Kloppenburg M, Min JL, Kroon HM, Houwing-Duistermaat JJ, Le Graverand MH, De Groot J & Slagboom E (2005), UCTX-II levels are influenced by radiographic osteoarthritis (OA) in hip, knee, hand, and facet joints in sibling pairs with familial OA at multiple sites. The GARP study, Annals of the Rheumatic Diseases 64.
- Alizadeh BZ, Njajou OT, Hazes JMW, Hofman A, Slagboom PE, Pols HAP & van Duijn CM (2004), The H63D mutation in the HFE gene predisposes to arthralgia, chondrocalcinosis, and osteoarthritis., Arthritis and Rheumatism 50(9).
- Riyazi N, Rosendaal FR, Slagboom E, Breedveld FC & Kloppenburg M (2004), Risk factors in familial osteoarthritis. The GARP sibling study, Osteoarthritis and Cartilage 12: S112-S112.
- Min J, Meulenbelt I, Kloppenburg M, Van Duijn CM & Slagboom E (2004), Genome wide scan in early onset generalized OA; Mutation and association analysis of candidate genes within the region of linkage, Annals of the Rheumatic Diseases 63: 120-120.
- Meulenbelt I, Min J, Kloppenburg M, Van Duijn CM & Slagboom E (2004), Genome wide scan in early onset generalized OA; Mutation analysis of a candidate gene, Annals of the Rheumatic Diseases 63: 120-120.
- Meulenbelt I, Kloppenburg G, Min J, Pickering E, Le Graverand MPH, Groot J & Slagboom PE (2004), Cross sectional evaluation of biochemical markers of bone and cartilage metabolism in sibling pairs with familial OA at multiple sites. The GARP study, Osteoarthritis and Cartilage 12: S92-S93.
- Willemsen G, Boomsma DI, Beem AL, Vink JM, Slagboom PE & Posthuma D (2004), QTLs for height: results of a full genome scan in Dutch sibling pairs, European Journal of Human Genetics 12(10).
- Riyazi N, Hulzinga TWJ, De Craen AJM, Meulenbelt I, Kroon HM, Rosendaal FR, Breedveld FC, Slagboom E & Kloppenburg M (2004), Identification of three new genetically determined risk factors for osteoarthritis (OA): High levels of interleukin (IL)-1beta and IL-receptor antagonist (IL-1Ra) and low IL-10 production, Annals of the Rheumatic Diseases 63.
- Riyazi N, Huizinga TJ, de Craen AR, Meulenbelt I, Kroon HM, Rosendaal R, Breedveld FC, Slagboom E & Kloppenburg M (2004), Identification of three new genetically determined risk factors for osteoarthritis (OA): High levels of interleukin (IL)-1 beta and IL-receptor antagonist (IL-1Ra) and low IL-10 production, Annals of the Rheumatic Diseases 63.
- Botha-Scheepers SA, Riyazi N, Kroon HM, Slagboom E, Meulebelt I, Rosendaal FR, Breedveld FC & Kloppenburg M (2004), Pain and disability in the lower extremities in patients with osteoarthritis (OA) at multiple sites are associated with lumbar spine OA, the number of oa joints, range of motion and psychological factors, Annals of the Rheumatic Diseases 63.
- Vink JM, Beem AL, Posthuma D, Neale MC, Willemsen G, Kendler KS, Slagboom PE & Boomsma DI (2004), Linkage analysis of smoking initiation and quantity in Dutch sibling pairs, Pharmacogenomics Journal 4(4).
- Heijmans BT, Beem AL, Willemsen G, Posthuma D, Slagboom PE & Boomsma DI (2004), Further evidence for a QTL influencing body mass index on chromosome 7p from a genome-wide scan in Dutch families, Twin Research 7(2).
- Beekman M, Posthuma D, Heijmans BT, Lakenberg N, Suchiman HED, Snieder H, de Knijff P, Frants RR, van Ommen GJB, Kluft C, Vogler GP, Slagboom PE & Boomsma DI (2004), Combined association and linkage analysis applied to the APOE locus, Genetic Epidemiology 26(4).
- Meulenbelt I, Seymour AB, Nieuwland M, Huizinga TWJ, van Duijn CM & Slagboom PE (2004), Association of the interleukin-1 gene cluster with radiographic signs of osteoarthritis of the hip, Arthritis and Rheumatism 50(4).
- Mooijaart, S.P.; Heemst, D. van; Schreuder, J.; Gerwen, S. van; Beekman, M.; Brandt, B.W.; Slagboom, P.E.; Westendorp, R.G.J. & Long Life Study Grp (2004), Variation in the SHC1 gene and longevity in humans, Experimental Gerontology 39(2).
- Alizadeh BZ, Njajou OT, Hazes JMW, Hofman A, Slagboom PE, Pols HAR & van Duijn CM (2004), The H63D mutation in the HFE gene predisposes to arthralgia, chondrocalcinosis, and osteoarthritis, Annals of the Rheumatic Diseases 63: 71-71.
- Zhai G, Rivadeneira F, Houwing-Duistermat JJ, Meulenbelt I, Bijkerk C, Hofman A, van Meurs JBJ, Uitterlinden AG, Pols HAP, Slagboom PE & van Duijn CM (2004), Insulin-like growth factor I gene promoter polymorphism, collagen type II alpha 1 (COL2A1) gene, and the prevalence of radiographic osteoarthritis: the Rotterdam Study, Annals of the Rheumatic Diseases 63(5).
- Riyazi N, Meulenbelt I, Kroon HM, le Graverand MPH, Woodworth T, Rosendaal FR, Breedveld FC, Slagboom PE & Kloppenburg M (2003), Evidence for familial aggregation of hip, hand and spine osteoarthritis (OA) in siblings with clinical and radiological OA. The GARP study., Arthritis and Rheumatism 48(9).
- Houwing-Duistermaat JJ, Bijkerk C, Hsu L, Stijnen T, Slagboom EP & van Duijn CM (2003), A unified approach to modelling linkage to quantitative and qualitative traits, Annals of Human Genetics 67.
- Beekman M, Heijmans BT, Martin NG, Whitfield JB, Pedersen NL, DeFaire U, Snieder H, Lakenberg N, Knijff PC, Frants RR, van Ommen GJB, Kluft C, Vogler GR, Slagboom RE & Boomsma DI (2003), Two-locus linkage analysis applied to putative quantitative trait loci for lipoprotein(a) levels, Twin Research 6(4).
- Heijmans BT, Boer JMA, Suchiman HED, Cornelisse CJ, Westendorp RGJ, Kromhout D, Feskens EJM & Slagboom PE (2003), A common variant of the methylenetetrahydrofolate reductase gene (1p36) is associated with an increased risk of cancer, Cancer Research 63(6).
- Beekman M, Heijmans BT, Martin NG, Whitfield JB, Pedersen NL, DeFaire U, Snieder H, Lakenberg N, Eka H, Suchiman D, de Knijff P, Frants RR, van Ommen GJB, Kluft C, Vogler GP, Boomsma DI & Slagboom PE (2003), Evidence for a QTL on chromosome 19 influencing LDL cholesterol levels in the general population, European Journal of Human Genetics 11(11).
- Meulenbelt I, Seymour A, Nieuwland M, Bijkerk C, Gabel CA, Huizinga T, van Duijn CM & Slagboom PE (2002), Interleukin-1 polymorphism significantly associated with increased risk for hip osteoarthritis in females., American Journal of Human Genetics 71(4): 347-347.
- Heijmans BT, Beekman M, Martin NG, Whitfield JB, Pedersen NI, DeFaire U, Snieder H, Lakenberg N, de Knijff P, Frants RR, van Ommen GJE, Kluft C, Vogler GP, Slagboom PE & Boomsma DI (2002), No evidence for a locus influencing Lp(a) levels cn chromosome, American Journal of Human Genetics 71(4): 454-454.
- van Aken MO, de Craen AJM, Gussekloo J, Moghaddam PH, Vandenbroucke JP, Heijmans BT, Slagboom PE & Westendorp RGJ (2002), No increase in mortality and morbidity among carriers of the C282Y mutation of the hereditary haemochromatosis gene in the oldest old: the Leiden 85-plus Study, European Journal of Clinical Investigation 32(10).
- Slagboom PE & Meulenbelt I (2002), Organisation of the human genome and our tools for identifying disease genes, Biological Psychology 61(1-2).
- Heijmans BT, Westendorp RGJ, Droog S, Kluft C, Knook D & Slagboom PE (2002), Association of the tumour necrosis factor alpha -308G/A polymorphism with the risk of diabetes in an elderly population-based cohort, Genes and Immunity 3(4).
- Beekman M, Heijmans BT, Martin NG, Pedersen NL, Whitfield JB, DeFaire U, van Baal GCM, Snieder H, Vogler GP, Slagboom PE & Boomsma DI (2002), Heritabilities of apolipoprotein and lipid levels in three countries, Twin Research 5(2).
- Heijmans BT, Slagboom PE, Gussekloo J, Droog S, Lagaay AM, Kluft C, Knook DL & Westendorp RGJ (2002), Association of APOE epsilon 2/epsilon 3/epsilon 4 and promoter gene variants with dementia but not cardiovascular mortality in old age, American Journal of Medical Genetics 107(3).
- Feskens EJM, Heijmans BT, Slagboom PE & Kromhout D (2001), Insulin gene VNTR associated with type 2 diabetes: Interactions with age, body fatness and height, Diabetologia 44: A87-A87.
- Heijmans BT, Beekman M, Lakenberg N, Suchiman HED, Vogler GP, DeFaire U, Whitfield JB, de Knijff P, Kluft C, van Ommen GJB, Frants RR, Pedersen NL, Martin NG, Boomsma DI & Slagboom PE (2001), Genome scan for cardiovascular risk factors in three populations., American Journal of Human Genetics 69(4): 502-502.
- Beekman M, Heijmans BT, Lakenberg N, Suchiman E, Vogler GP, Martin NG, Whitfield JB, Pedersen NL, Kluft C, van Ommen GJB, Frants RR, de Knijff P, Slagboom E & Boomsma DI (2001), Genome scan for quantitative traits involved in cardiovascular disease in three independent populations., Behavior Genetics 31(5): 447-447.
- Beekman M, Lakenburg N, Cherny SS, De Knijff P, Kluft CC, Van Ommen GJB, Vogler GP, Frants RR, Boomsma DI & Slagboom PE (2001), A powerful and rapid approach to human genome scanning using small quantities of genomic DNA, Genetics Research 77(2).
- Duffy D, Montgomery G, Treloar S, Birley A, Kirk K, Boomsma D, Beem L, de Geus E, Slagboom E, Knighton J, Reed P & Martin N (2001), IBD sharing around the PPARG locus is not increased in dizygotic twins or their mothers, Nature Genetics 28(4).
- Meulenbelt I, Slagboom PE & van Duijn C (2000), Analysis of the association of the matrillin-1 gene (CRTM) with osteoarthritis: comment on the article by Meulenbelt et al - Reply.
- van Meurs JBJ, Arp PP, Fang Y, Slagboom PE, Meulenbelt I, van Leeuwen JPTM, Pols HAP & Uitterlinden AG (2000), Detection of sequence variability of the collagen type II alpha 1 3 ' variable number of tandem repeat, ELECTROPHORESIS 21(17).
- Heijmans BT, Westendorp RGJ & Slagboom PE (2000), Common gene variants, mortality and extreme longevity in humans, Experimental Gerontology 35(6-7).
- Slagboom PE, Heijmans BT, Beekman M, Westendorp RGJ & Meulenbelt I (2000), Genetics of human aging - The search for genes contributing to human longevity and diseases of the old.
- Heijmans BT, Westendorp RGJ, Lagaay AM, Knook DL, Kluft C & Slagboom PE (2000), Common paraoxonase gene variants, mortality risk and fatal cardiovascular events in elderly subjects.
- Heijmans BT, Westendorp RGJ, Knook DL, Kluft C & Slagboom PE (1999), Paraoxonase Met-55/Leu and Gln-192/Arg polymorphisms and the risk of mortality and fatal cardiovascular events in elderly subjects, Atherosclerosis 144: 18-18.
- Heiimans BT, Gussekloo J, Kluft C, Droog S, Lagaay AM, Knook DL, Westendorp RGJ & Slagboom PE (1999), Increased risk of mortality associated with a common mutation in the methylenetetrahydrofolate reductase gene (MTHFR), Zeitschrift f�r Gerontologie und Geriatrie 32(2): 146-146.
- Beekman M, Boomsma DI, De Knijff P, Vogler GP, Kluft CC, Van Ommen GJB, Frants RR & Slagboom PE (1999), Genome scan for quantitative traits involved in cardiovascular disease., American Journal of Human Genetics 65(4): A243-A243.
- Heijmans BT, Westendorp RGJ, Knook DL, Kluft C & Slagboom PE (1999), Angiotensin I-converting enzyme and plasminogen activator inhibitor-1 gene variants: Risk of mortality and fatal cardiovascular disease in an elderly population-based cohort, Journal of the American College of Cardiology 34(4): 1176-1183.
- Gussekloo J, Heijmans BT, Lagaay AM, Slagboom PE, Knook DL & Westendorp RGJ (1999), A common Methylenetetrahydrofolate Reductase polymorphism and cognitive decline in the oldest old., Zeitschrift f�r Gerontologie und Geriatrie 32(2): 120-120.
- Slagboom PE, Bijkerk C, Houwing-Duistermaat JJ, Valkenburg HA, Meulenbelt I, Hofman A, Breedveld FC, Pols HAP & van Duijn CM (1999), Heritability and candidate gene studies in Osteoarthritis, Zeitschrift f�r Gerontologie und Geriatrie 32(2): 127-127.
- Meulenbelt I, Bijkerk C, Houwing-Duistermaat JJ, Breedveld FC, van Duijn CM & Slagboom PE (1999), Genetic studies on osteoarthritis., American Journal of Human Genetics 65(4): A435-A435.
- Bijkerk C, Houwing-Duistermaat JJ, Valkenburg HA, Meulenbelt I, Hofman A, Breedveld FC, Pols HAP, van Duijn CM & Slagboom PE (1999), Heritabilities of radiologic osteoarthritis in peripheral joints and of disc degeneration of the spine, Arthritis and Rheumatism 42(8): 1729-1735.
- Meulenbelt I, Bijkerk C, De Wildt SCM, Miedema HS, Breedveld FC, Pols HAP, Hofman A, Van Duijn CM & Slagboom PE (1999), Haplotype analysis of three polymorphisms of the COL2A1 gene and associations with generalised radiological osteoarthritis.
- Westendorp RGJ, Hottenga JJ & Slagboom PE (1999), Variation in plasminogen-activator-inhibitor-1 gene and risk of meningococcal septic shock, Lancet 354(9178): 561-563.
- Westendorp RGJ, Knook DL & Slagboom PE (1999), Saving time to reveal determinants of disease at old age, Zeitschrift f�r Gerontologie und Geriatrie 32(2): 47-47.