Annemarie Meijer
Professor of Immunobiology
- Name
- Prof.dr. A.H. Meijer
- Telephone
- +31 71 527 4927
- a.h.meijer@biology.leidenuniv.nl
- ORCID iD
- 0000-0002-1325-0725
I am professor of Immunobiology and head of the Animal Sciences research cluster. I am interested in host-pathogen interactions and work with zebrafish models for infection with intracellular bacterial pathogens, like Mycobacteria and Salmonella, to study mechanisms of host defence. I am also Confidential Counsellor for PhD students of the Graduate School of the Faculty of Science.
More information about Annemarie Meijer
PhD Candidates
Postdocs
News
Former PhD candidates
Dissertations
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Autophagy and Lc3-associated phagocytosis in host defense against Salmonella
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Selective autophagy in host defense against mycobacterial infection
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The role of the tumor suppressor Lkb1 in energy homeostatis
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Exploitation of host chemokine signalling by pathogenic mycobacteria
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Cell-autonomous and host-dependent CXCR4 signaling in cancer metastasis : insights from a zebrafish xenograft model
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Toll-like receptor signaling in the innate immune system of zebrafish larvae
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Network properties of the mammalian circadian clock
Research
My research focuses on the immunobiology of host-pathogen interactions. I study mechanisms of host defence against intracellular bacterial pathogens responsible for infectious diseases like tuberculosis and typhoid fever. The causative agents of these diseases, Mycobacteria and Salmonella, parasitize one of the major cell types of the innate immune system, the macrophage. In my group, we use the optically transparent and genetically accessible early life stages of the zebrafish to study macrophage defence mechanisms in a whole organism model system.
Host-pathogen interaction mechanisms
Intracellular bacterial pathogens, such as Mycobacteria and Salmonella, have a remarkable ability to manipulate host signalling pathways in order to promote their survival and spreading through host tissues. In my group, we use reverse genetics approaches to study the host factors involved in combatting these persistent pathogens. We also study responses to opportunistic pathogens, like Staphylococcus bacteria and Aspergillus fungi. Recent work has shed new light on the interaction between macrophages and neutrophils in nitric oxide-mediated host defence. Furthermore, current research efforts are strongly concentrated on the discovery of an autophagy regulator that protects against mycobacterial infection and that forms a missing link between pathogen recognition and autophagic host defence. In collaborative projects, we also use our infection models to screen for novel immunomodulatory drugs for infectious disease treatment.
Activation of the immune defences
We developed zebrafish models for immunodeficiency and autoinflammation by mutation or knockdown of central factors in innate immunity signalling, conserved between the zebrafish and human. By RNA sequencing of whole infected embryos and sorted macrophages, we gained insight into the host immune response genes activated at specific stages of infection with different pathogens. Based on these extensive expression profiling studies, we selected host genes for loss and gain of function studies. Genes currently under investigation include several early macrophage-specific genes, such as a receptor that we have shown to be required for macrophage migration to chemokine signals released at infection foci and that contributes to the dissemination of mycobacterial infection through host tissues. The ultimate aim of these studies is to identify host targets for the development of novel therapeutic strategies.
Group Members
Current group members
- Michiel van der Vaart – assistant professor
- Monica Varela Álvarez – postdoc, VENI
- Gabriel Forn-Cuni – postdoc, Marie Skłodowska-Curie COFUND fellowship
- Ralf Boland – PhD student, STW
- Yufei Xie – PhD student, CSC fellowship
- Frida Sommer – PhD student, CONACYT fellowship
- Salomé Munoz Sanchez – PhD student, Marie Skłodowska-Curie ITN ImageInLife
- Mahmoud Halima – PhD student, LUECCM
- Jiajun Xie - PhD student
- Guus van der Velden – Fish facility coordinator
Previous group members
- Vincenzo Torraca – PhD student, FishForPharma Project
- Julien Rougeot – postdoc, FishForPharma Project
- Erica Benard - PhD student, SmartMix project
- Philip Elks - postdoc, ERS fellowship
- Chao Cui - PhD student, SmartMix project
- Zakia Kanwal, PhD student, HEC Pakistan fellowship
- Peter Racz - postdoc, Marie-Curie fellowship
- Joost van Soest – PhD student, University funding
- Oliver Stockhammer – PhD student/postdoc, University funding/ZF-HEALTH project
- Anna Zakrzewska - postdoc, EU ZF-TOOLS and Horizon Breakthrough project
- Anita Ordas - project manager, FishForPharma project
- Tomacz Prajsnar – postdoc, Marie Curie IEF
- Bjorn Koch – postdoc, EU
- Samrah Masud – PhD student, HEC Pakistan fellowship
- Rui Zhang – PhD student, CSC fellowship
Professor of Immunobiology
- Science
- Instituut Biologie Leiden
- IBL Animal Sciences
Confidential counsellor
- Bestuursbureau
- Vertrouwenspersonen
- Masud S., Xie J., Grijmans B.J.M., Kooij S. van der, Zhang R., Prajsnar T.K. & Meijer A.H. (2023), DRAM1 confers resistance to Salmonella infection, Autophagy Reports 2(1): 2242715 .
- Hammond F.R., Lewis A., Speirs Z.C., Anderson Holly. E., Sipka T., Williams L.G., Nguyen-Chi M., Meijer A.H., Wiegertjes G.F. & Elks P.M. (2023), An arginase 2 promoter transgenic line illuminates immune cell polarisation in zebrafish, Disease Models & Mechanisms 16(6): dmm049966.
- Banducci-Karp A., Xie J., Engels S.A.G., Sarantaris C., Hage P. van, Varela M., Meijer A.H. & Vaart M. van der (2023), DRAM1 promotes lysosomal delivery of mycobacterium marinum in macrophages, Cells 12(6): 828.
- Muñoz-Sánchez S., Varela M., Vaart M. van der & Meijer A.H. (2023), Using zebrafish to dissect the interaction of mycobacteria with the autophagic machinery in macrophages, Biology 12(6): 817.
- Alen I. van, Aguirre García M.A., Maaskant J.J, Kuijl C.P., Bitter W., Meijer A.H. & Ubbink M. (2023), Mycobacterium tuberculosis β-lactamase variant reduces sensitivity to ampicillin/avibactam in a zebrafish-Mycobacterium marinum model of tuberculosis, Scientific Reports 13: 15406.
- Boland R., Heemskerk M.T., Forn-Cuní G., Korbee C.J., Walburg K.V., Esselink J.J., Carvalho dos Santos C., Waal A.M. de, Hoeven D.C.M. van der, Sar E. van der, Ries A.S. de, Xie J., Spaink H.P., Vaart M. van der, Haks M.C., Meijer A.H. & Ottenhoff T.H.M. (2023), Repurposing tamoxifen as potential host-directed therapeutic for tuberculosis, mBio 14(1): e03024.
- Forn Cuni G., Welvaarts L., Stel F.M., Hondel C.A.M.J.J. van den, Arentshorst M., Ram A.F.J. & Meijer A.H. (2023), Stimulating the autophagic-lysosomal axis enhances host defense against fungal infection in a zebrafish model of invasive Aspergillosis, Autophagy 1986(1): 324-337.
- Rashid F.Z.M., Mahlandt E., Vaart M. van der, Boer D.E.C., Valera Alvarez M., Henneman B., Brocken D.J.W., Voskamp P., Blok A.J., Shimizu T.S., Meijer A.H., Luijsterburg M.S., Goedhart J., Cremazy F.G.E. & Dame R.T. (2022), HI-NESS: a family of genetically encoded DNA labels based on a bacterial nucleoid-associated protein, Nucleic Acids Research 50(2): e10.
- Lelieveld L.T., Gerhardt S., Maas S., Zwiers K.C., Wit C. de, Beijk E.H., Guimaraes Da Lomba Ferraz M.J., Artola Perez de Azanza M.E., Meijer A.H., Tudorache C., Salvatori D., Boot R.G. & Aerts J.M.F.G. (2022), Consequences of excessive glucosylsphingosine in glucocerebrosidase-deficient zebrafish, Journal of Lipid Research 63(5): 100199.
- Varela Alvarez M. & Meijer A.H. (2022), A fresh look at mycobacterial pathogenicity with the zebrafish host model, Molecular Microbiology 117(3): 661-669.
- Grijmans B.J.M., Kooij S.B. van der, Varela Alvarez M. & Meijer A.H. (2022), LAPped in proof: LC3‐associated phagocytosis and the arms race against bacterial pathogens, Frontiers in Cellular and Infection Microbiology 11: 809121.
- Hosseini R., Lamers G.E.M., Bos E., Hogendoorn P.C.W., Koster A.J., Meijer A.H., Spaink H.P. & Schaaf M.J.M. (2021), The adapter protein Myd88 plays an important role in limiting mycobacterial growth in a zebrafish model for tuberculosis, Virchows Archiv 479(2): 265-275.
- Xie Y., Xie J., Meijer A.H. & Schaaf M.J.M. (2021), Glucocorticoid-induced exacerbation of mycobacterial infection is associated with a reduced phagocytic capacity of macrophages, Frontiers in Immunology 12: 618569.
- Sommer F., Torraca V., Xie Y., Veld A.E. in 't, Willemse J.J. & Meijer A.H. (2021), Disruption of Cxcr3 chemotactic signaling alters lysosomal function and renders macrophages more microbicidal, Cell Reports 35(2): 10900.
- Rashid F.Z.M., Mahlandt E., Vaart M van der, Boer D.E.C., Varela Alvarez M., Henneman B., Brocken D.J.W., Voskamp P., Blok A.J., Shimizu T.S., Meijer A.H., Luijsterburg M.S., Goedhart J., Crémazy F.G.E. & Dame R.T. (2021), HI-NESS: a family of genetically encoded DNA labels based on a bacterial nucleoid-associated protein, Nucleic Acids Research 50(2): e10.
- Keizer E.M., Valdes I.D., Forn-Cuni G., Klijn E., Meijer A.H., Hillmann F., Wösten H.A.B. & Cock H. de (2021), Correction: Variation of virulence of five Aspergillus fumigatus isolates in four different infection models, PLoS ONE 16(9): e0252948.
- Sommer F., Ortiz Zacarıas N.V., Heitman L.H. & Meijer A.H. (2021), Inhibition of macrophage migration in zebrafish larvae demonstrates in vivo efficacy of human CCR2 inhibitors, Developmental and Comparative Immunology 116: 103932.
- Xie Y., Meijer A.H. & Schaaf M.J.M. (2021), Modeling inflammation in zebrafish for the development of anti-inflammatory drugs, Frontiers in Cell and Developmental Biology 8: 620984.
- Koch B.E.V., Spaink H.P. & Meijer A.H. (2021), A quantitative in vivo assay for craniofacial developmental toxicity of histone deacetylases, Toxicology Letters 342: 20-25.
- Meijer A.H. & et al. (2021), Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition), Autophagy 17(1): 1-382.
- Keizer E.M., Valdes I.D., Forn-Cuni G., Klijn E., Meijer A.H., Hillman F., Wosten H.A.B. & Cock H. de (2021), Variation of virulence of five Aspergillus fumigatus isolates in four different infection models, PLoS ONE 16(7): e0252948.
- Prajsnar T.K., Serba J.J., Dekker B.M., Gibson J.F., Masud S., Fleming A., Johnston S.A., Renshaw S.A. & Meijer A.H. (2021), The autophagic response to Staphylococcus aureus provides an intracellular niche in neutrophils, Autophagy 17(4): 888-902.
- Leeuwe T.M. van, Wattjes J., Niehues A., Forn-Cuní G., Geoffrion N., Mélida H., Arentshorst M., Molina A.,Tsang A., Meijer A.H., Moerschbacher B.M., Punt P.J. & Ram A.F.J. (2020), A seven-membered cell wall related transglycosylase gene family in Aspergillus niger is relevant for cell wall integrity in cell wall mutants with reduced α-glucan or galactomannan, Cell Surface 6: 100039.
- He M., Halima M., Xie Y., Schaaf M.J.M., Meijer A.H. & Wang M. (2020), Ginsenoside Rg1 acts as a selective glucocorticoid receptor agonist with anti-inflammatory action without affecting tissue regeneration in zebrafish larvae , Cells 9(5): 1107.
- Sommer F., Torraca V. & Meijer A.H. (2020), Chemokine receptors and phagocyte biology in zebrafish , Frontiers in Immunology 11: 325.
- Moreira J.D., Koch B.E.V., Veen S. van, Walburg K.V., Vrieling F., Pinto Dabés Guimarães T.M., Meijer A.H., Spaink H.P., Ottenhoff T.H.M., Haks M.C. & Heemskerk M.T. (2020), Functional inhibition of host histone deacetylases (HDACs) enhances in vitro and in vivo anti-mycobacterial activity in human macrophages and in zebrafish , Frontiers in Immunology 11: 36.
- Leeuwe T.M. van, Arentshorst M., Forn-Cuní G., Geoffrion N., Tsang A., Delvigne F., Meijer A.H., Ram A.F.J. & Punt P.J. (2020), Deletion of the Aspergillus niger pro-protein processing protease gene kexB results in a pH-dependent morphological transition during submerged cultivations and increases cell wall chitin content , Microorganisms 8(12): 1918.
- Puyskens A., Stinn A., Vaart M. van der, Kreuchwig A., Protze J., Pei G., Klemm M., Guhlich-Bornhof U., Hurwitz R., Krishnamoorthy G., Schaaf M.J.M., Krause G., Meijer A.H., Kaufmann S.H.E. & Moura-Alves P. (2020), Aryl hydrocarbon receptor modulation by tuberculosis drugs impairs host defense and treatment outcomes , Cell Host & Microbe 27(2): 238-248.e7.
- Zhang R., Varela Alvarez M., Forn-Cuní G., Torraca V., Vaart M. van der & Meijer A.H. (2020), Deficiency in the autophagy modulator Dram1 exacerbates pyroptotic cell death of Mycobacteria-infected macrophages, Cell Death and Disease 11(4): 277.
- Muñoz-Sánchez S., Vaart M. van der & Meijer A.H. (2020), Autophagy and Lc3-associated phagocytosis in zebrafish models of bacterial infections , Cells 9(11): 2372.
- Sommer F., Ortiz Zacarías N.V., Heitman L.H. & Meijer A.H. (2020), Inhibition of macrophage migration in zebrafish larvae demonstrates in vivo efficacy of human CCR2 inhibitors, Developmental and Comparative Immunology 116: 103932.
- Kuo C.L., Kallemeijn W.W., Lelieveld L.T., Mirzaian M., Zoutendijk I., Vardi A., Futerman A.H., Meijer A.H., Spaink H.P., Overkleeft H.S., Aerts J.M.F.G. & Artola Perez de Azanza M.E. (2019), In vivo inactivation of glycosidases by conduritol B epoxide and cyclophellitol as revealed by activity‐based protein profiling, FEBS Journal 286(3): 584-600.
- Rougeot J., Torraca V., Zakrewska A., Kanwal Z., Jansen H.J., Sommer F., Spaink H.P. & Meijer A.H. (2019), RNAseq Profiling of Leukocyte Populations in Zebrafish Larvae Reveals a cxcl11 Chemokine Gene as a Marker of Macrophage Polarization During Mycobacterial Infection, Frontiers in Immunology 10: 832.
- Lelieveld L.T., Mirzaian M., Kuo C.L., Artola Perez de Azanza M.E., Guimaraes da Lomba Ferraz M.J., Peter R.E.A., Akiyama H., Greimel P., Berg R.J.B.H.N. van den, Overkleeft H.S., Boot R.G., Meijer A. & Aerts J.M.F.G. (2019), Role of β-glucosidase 2 in aberrant glycosphingolipid metabolism: model of glucocerebrosidase deficiency in zebrafish, Journal of Lipid Research 60(11): 1851-1867.
- Hu W., Yang S., Shimada Y., Münch M., Marín-Juez R., Meijer A.H. & Spaink H.P. (2019), Infection and RNA-seq analysis of a zebrafish tlr2 mutant shows a broad function of this toll-like receptor in transcriptional and metabolic control and defense to Mycobacterium marinum infection, BMC Genomics 20: 878.
- Sommer F., Torraca V., Kamel S.M., Lombardi A. & Meijer A.H. (2019), Frontline Science: antagonism between regular and atypical Cxcr3 receptors regulates macrophage migration during infection and injury in zebrafish, Journal of Leukocyte Biology 107(2): 185-203.
- Koch B.E.V., Hajdamowicz N.H., Lagendijk E., Ram A.F.J. & Meijer A.H. (2019), Aspergillus fumigatus establishes infection in zebrafish by germination of phagocytized conidia, while Aspergillus niger relies on extracellular germination, Scientific Reports 9: 12791.
- Xie Y., Tolmeijer S., Oskam J.M., Tonkens T., Meijer A.H. & Schaaf M.J.M. (2019), Glucocorticoids inhibit macrophage differentiation towards a pro-inflammatory phenotype upon wounding without affecting their migration, Disease Models & Mechanisms 12(5): 037887.
- Cordero-Maldonado M.L., Perathoner S., Kolk K.J. van der, Boland R., Heins-Marroquin U., Spaink H.P., Meijer A.H., Crawford A.D. & Sonneville J. de (2019), Deep learning image recognition enables efficient genome editing in zebrafish by automated injections, PLOS One 14(1): e0202377.
- Rougeot J., Torraca V., Zakrzewska A., Kanwal Z., Jansen H. & Meijer A.H. (2019), RNAseq profiling of leukocyte populations in zebrafish larvae reveals a cxcl11 chemokine gene as a marker of macrophage polarization during mycobacterial infection, Frontiers in Immunology 10: 832.
- Rahman A., Henry K.M., Herman K.D., Thompson A.A., Isles H.M., Tulotta C., Sammut D., Rougeot J.J., Khoshaein N., Reese A.E., Higgins K., Tabor C., Sabroe I., Zuercher W.J., Savage C.O., Meijer A.H., Whyte M.K., Dockrell D.H., Renshaw S.A. & Prince L.R. (2019), Inhibition of ErbB kinase signalling promotes resolution of neutrophilic inflammation, eLife 8: e50990.
- Forn-Cuní G., Meijer A.H. & Varela Alvarez M. (2019), Zebrafish in Inflammasome Research, Cells 8(8): 901.
- Masud S., Burg L.L.J. van der, Storm L., Prajsnar T.K. & Meijer A.H. (2019), Rubicon-dependent Lc3 recruitment to Salmonella-containing phagosomes is a host defense mechanism triggered independently from major bacterial virulence factors, Frontiers in Cellular and Infection Microbiology 9: 279.
- Zhang R., Varela Alvarez M., Vallentgoed W., Forn-Cuní G., Vaart M. van der & Meijer A.H. (2019), The selective autophagy receptors Optineurin and p62 are both required for zebrafish host resistance to mycobacterial infection, PLoS Pathogens 15(2): e1007329.
- Ogryzko N.V., Lewis A., Wilson H.L., Meijer A.H., Renshaw S.A. & Elks P.M. (2019), Hif-1 alpha-Induced Expression of Il-1 beta Protects against Mycobacterial Infection in Zebrafish, Journal of Immunology 202(2): 494-502.
- Masud S., Prajsnar T.K., Torraca V., Lamers G.E.M., Benning M., Vaart M. van der & Meijer A.H. (2019), Macrophages target Salmonella by Lc3-associated phagocytosis in a systemic infection model, Autophagy 15(5): 796-812.
- Tulotta C., Stefanescu C., Chen Q., Torraca V., Meijer A.M. & Snaar-Jagalska B.E. (2019), CXCR4 signaling regulates metastatic onset by controlling neutrophil motility and response to malignant cells, Scientific Reports 9: 2399.
- Kuo C.L., Kallemeijn W.W., Lelieveld L.T., Mirzaian M., Zoutendijk I., Vardi A., Futerman A.H., Meijer A.H., Spaink H.P., Overkleeft H.S., Aerts J.M.F.G. & Artola M. (2019), In vivo inactivation of glycosidases by conduritol B epoxide and cyclophellitol as revealed by activity-based protein profiling, FEBS Journal 286(3): 584-600.
- Tudorache C., Slabbekoorn H.W., Robbers Y., Hin E., Meijer A.H., Spaink H.P. & Schaaf M.J.M. (2018), Biological clock function is linked to proactive and reactive personality types, BMC Biology 16: 148.
- Shao J., Haider I., Xiong L., Zhu X., Hussain R.M.F., Övernäs E., Meijer A.H., Zhang G., Wang M., Bouwmeester H.J. & Ouwerkerk P.B.F. (2018), Functional analysis of the HD-Zip transcription factor genes Oshox12 and Oshox14 in rice, PLOS ONE 13(7): e0199248.
- Troll J.V., Hamilton M.K., Abel M.L., Ganz J., Bates J.M., Stephens W.Z., Melancon E., Vaart M. van der, Meijer A.H., Distel M., Eisen J.S. & Guillemin K. (2018), Microbiota promote secretory cell determination in the intestinal epithelium by modulating host Notch signaling, ChemBioChem 145(4): 1766 -1770.
- Elsland D.M. van, Pujals S., Bakkum T., Bos E., Oikonomeas-Koppasis N., Berlin I., Neefjes J., Meijer A.H., Koster A.J., Albertazzi L. & Kasteren S.I. van (2018), Ultrastructural Imaging of Salmonella-Host Interactions Using Super-resolution Correlative Light-Electron Microscopy of Bioorthogonal Pathogens, ChemBioChem 19(16): 1766-1770.
- He M., Huang X., Liu S., Guo C., Xie Y., Meijer A.H. & Wang M. (2018), The Difference between White and Red Ginseng: Variations in Ginsenosides and Immunomodulation, Planta Medica 84(12/13): 845-854.
- Travin D., Popov I., Guler A.T., Medvedev D., Plas-Duivesteijn S. van der, Varela Alvarez M., Kolder I.C.R.M., Meijer A.H., Spaink H.P. & Palmblad M. (2018), COMICS: Cartoon Visualization of Omics Data in Spatial Context Using Anatomical Ontologies, Journal of Proteome Research 17(1): 739-744.
- Vergunst A.C., Carranza N.L., Zhang L., Gomes M.C., Tasrini Y., Meijer A.H. & O'Callaghan D. (2017), Macrophages as drivers of an opportunistic infection, Microbial Cell 4(10): 362-364.
- Masud S., Torraca V. & Meijer A.H. (2017), Modeling Infectious Diseases in the Context of a Developing Immune System, Current Topics in Developmental Biology 124: 277-329.
- Salamaga B., Prajsnar T.K., Jareno-Martinez A., Willemse J.J., Bewley M.A., Chau F., Ben Belkacem T., Meijer A.H., Dockrell D.H., Renshaw S.A. & Mesnage S. (2017), Bacterial size matters: Multiple mechanisms controlling septum cleavage and diplococcus formation are critical for the virulence of the opportunistic pathogen Enterococcus faecalis, PLoS Pathogens 13(7): e1006526.
- Chatzopoulou A., Schoonheim P.J., Torraca V., Meijer A.H., Spaink H.P. & Schaaf M.J.M. (2017), Functional analysis reveals no transcriptional role for glucocorticoid receptor beta-isoform in zebrafish, Molecular and Cellular Endocrinology 447: 61-70.
- Mathai Benan J., Meijer A.H. & Simonsen A. (2017), Studying Autophagy in Zebrafish, Cells 6(3): 21.
- Mesureur J.S., Feliciano J.R., Wagner N., Gomes M.C., Zhang L., Blanco-Gonzalez M., Vaart M. van der, O'Callaghan D., Meijer A.H. & Vergunst A.C. (2017), Correction: macrophages, but not neutrophils, are critical for proliferation of Burkholderia cenocepacia and ensuing host-damaging inflammation, PLoS Pathogens 13(12): e100679.
- Foulkes M.J., Henry K.M., Rougeot J.J.Y., Hooper-Greenhill E., Loynes Catherine A., Jeffrey P., Fleming A., Savage C.O., Meijer A.H., Jones S. & Renshaw S.A. (2017), Expression and regulation of drug transporters in vertebrate neutrophils, Scientific Reports 7: 4967.
- Leist M., Ghallab A., Graepel R., Marcahn R., Hassan R., Hougaard Bennekou S., Limonciel A., Vinken M., Schildknecht S., Waldmann T., Danen E.H.J., Ravenzway B. van, Kamp H., Gardner I., Godoy P., Bois F.Y., Braeuning A., Reif R., Oesch F., Drasdo D., Hoehme S., Schwarz M., Hartung T., Braunbeck T., Beltman J.B., Vrieling H., Sanza F., Forsby A., Gadaleta D., Fisher C., Kelm J., Fluri D., Ecker G., Zdrqazil B., terron A., Jennings P., Burg B. van der, Dooley S., Meijer A.H., Willighagen E., Martens M., Evelo C., Mombelli E., Taboureau O., Manovani A., Hardy B., Koch B., Escher S., Thriel C. van, Cadenas C., Kroese D., Water B. van de & Hengstler J.G. (2017), Adverse outcome pathways : opportunities, limitations and open questions, Archives of Toxicology 91(11): 3477-3505.
- Torraca V., Tulotta C., Snaar-Jagalska B.E. & Meijer A.H. (2017), The chemokine receptor CXCR4 promotes granuloma formation by sustaining a mycobacteria-induced angiogenesis programme, Scientific Reports 7: 45061.
- Torraca V., Otto N.A., Tavakoli-Tameh A. & Meijer A.H. (2017), The inflammatory chemokine Cxcl18b exerts neutrophil-specific chemotaxis via the promiscuous chemokine receptor Cxcr2 in zebrafish, Developmental and Comparative Immunology 67: 57-65.
- Meijer A.H. & Aerts J.M.F.G. (2016), Linking Smokers' Susceptibility to Tuberculosis with Lysosomal Storage Disorders, Developmental Cell 37(2): 112-113.
- Benard E.L., Rougeot J.J.Y., Racz P.I., Spaink H.P. & Meijer A.H. (2016), Transcriptomic Approaches in the Zebrafish Model for Tuberculosis-Insights Into Host- and Pathogen-specific Determinants of the Innate Immune Response, Advances in Genetics 95: 217-251.
- Chatzopoulou Chatzi A., Heijmans J.P., Burgerhout E., Oskam N., Spaink H.P., Meijer A.H. & Schaaf M.J.M. (2016), Glucocorticoid-Induced Attenuation of the Inflammatory Response in Zebrafish, Endocrinology 157(7): 2772-2784.
- Hosseini R., Lamers G.E.M., Soltani H.M., Meijer A.H., Spaink H.P. & Schaaf M.J.M. (2016), Efferocytosis and extrusion of leukocytes determine the progression of early mycobacterial pathogenesis, Journal of Cell Science 129(18): 3385-3395.
- Meijer A.H. (2016), Protection and pathology in TB: learning from the zebrafish model, Springer Seminars in Immunopathology 38(2): 261-273.
- Tulotta C., He S., Chen L., Groenewoud A., Ent W. van der, Meijer A.H., Spaink H.P. & Snaar-Jagalska B.E. (2016), Imaging of human cancer cell proliferation, invasion, and micrometastasis in a zebrafish xenogeneic engraftment model. In: Kawakami K., Patton E.E. & Orger M. (Eds.), Zebrafish. Methods in Molecular Biology no. 1451. New York: Springer. 155-169.
- Torraca V., Cui C., Boland R., Bebelman J.P., Sar A.M. van der, Smit M.J., Siderius M., Spaink H.P. & Meijer A.H. (2015), The CXCR3-CXCL11 signaling axis mediates macrophage recruitment and dissemination of mycobacterial infection, Disease Models & Mechanisms 8(017756): 253-269.
- Meijer A.H. (Ed.) (2015), Advisory Board Member of Disease Models and Mechanisms. Disease Models & Mechanisms: The Company of Biologists.
- Elks P.M., Renshaw S.A., Meijer A.H., Walmsley S.R. & Eeden F.J. van (2015), Exploring the HIFs, buts and maybes of hypoxia signalling in disease: lessons from zebrafish models, Disease Models & Mechanisms 8(11): 1349-1360.
- Veneman W.J., Sonneville J. de, Kolk K.J. van der, Ordas A., Al-Ars Z., Meijer A.H. & Spaink H.P. (2015), Analysis of RNAseq datasets from a comparative infectious disease zebrafish model using GeneTiles bioinformatics, Immunogenetics 67(3): 135-147.
- LeBert D.C., Squirrell J.M., Rindy J., Broadbridge E., Lui Y., Zakrzewska A., Eliceiri K.W., Meijer A.H. & Huttenlocher A. (2015), Matrix metalloproteinase 9 modulates collagen matrices and wound repair, Development 142(12): 2136-2146.
- Yang S., Marin Juez R., Meijer A.H. & Spaink H.P. (2015), Common and specific downstream signaling targets controlled by Tlr2 and Tlr5 innate immune signaling in zebrafish, BMC Genomics 16(1): 547.
- Chatzopoulou Chatzi A., Upasana R., Meijer A.H., Alia A., Spaink H.P. & Schaaf M.J.M. (2015), Transcriptional and metabolic effects of glucocorticoid receptor alpha and beta signaling in zebrafish, Endocrinology 156(5): 1757-1769.
- Meijer A.H. (Ed.) (2015), Scientific Reports. Scientific Reports: Nature Publishing Group.
- Benard E.L., Racz P.I., Rougeot J.Y.Y., Nezhinsky A.E., Verbeek F.J., Spaink H.P. & Meijer A.H. (2015), Macrophage-expressed perforins Mpeg1 and Mpeg1.2 have an anti-bacterial function in zebrafish, Journal of Innate Immunity 7(2): 136-152.
- Ordas A., Raterink R., Cunningham F., Jansen H.J., Wiweger M.I., Jong-Raadsen S., Bos S., Bates R.H., Barros D., Meijer A.H., Vreeken R.J., Ballell-Pages L., Dirks R.P.H., Hankemeier T. & Spaink H.P. (2015), Testing tuberculosis drug efficacy in a zebrafish high-throughput translational medicine screen, Antimicrobial Agents and Chemotherapy 59(2): 753-762.
- Fink I.R., Benard E.L., Hermsen T., Meijer A.H., Forlenza M. & Wiegertjes G.F. (2015), Molecular and functional characterization of the scavenger receptor CD36 in zebrafish and common carp, Molecular Immunology 63(2): 381-393.
- Meijer A.H., Vaart M. van der & Spaink H.P. (2014), Real-time imaging and genetic dissection of host-microbe interactions in zebrafish, Cellular Microbiology 16(1): 39-49.
- Varela M., Romero A., Dios S., Vaart M. van der, Figueras A., Meijer AH. & Novoa B. (2014), Cellular Visualization of Macrophage Pyroptosis and IL1β Release in a Viral Hemorrhagic Infection in Zebrafish Larvae, Journal of Virology : .
- Kuijt S.J.H., Greco R., Agalou A., Shao J., Hoen C.C.J. 't, Övernäs E., Osnato M., Curiale S., Meynard D., Gulik R. van, Faria Maraschin S. de, Atallah M., Kam R.J. de, Lamers G.E.M., Guiderdoni E., Rossini L., Meijer A.H. & Ouwerkerk P.B.F. (2014), Interaction between the GROWTH-REGULATING FACTOR and KNOTTED1-LIKE HOMEOBOX Families of Transcription Factors, Plant Physiology 164(4): 1952-1966.
- Hosseini R., Lamers G.E.M., Hodzic Z., Meijer A.H., Schaaf M.J.M. & Spaink H.P. (2014), Correlative light and electron microscopy imaging of autophagy in a zebrafish infection model, Autophagy 10(10): 1844-1857.
- Elks P.M., Vaart M. van der, Hensbergen V. van, Schutz E., Redd M.J., Murayama E., Spaink H.P. & Meijer A.H. (2014), Mycobacteria Counteract a TLR-Mediated Nitrosative Defense Mechanism in a Zebrafish Infection Model, PLoS ONE 9(6): e100928.
- Rougeot J., Zakrzewska A., Kanwal Z., Jansen H.J., Spaink H.P. & Meijer A.H. (2014), RNA sequencing of FACS-sorted immune cell populations from zebrafish infection models to identify cell specific responses to intracellular pathogens, Methods in Molecular Biology 1197: 261-274.
- Plas-Duivestein S.J. van der, Mohammed Y.T., Dalebout H., Meijer A.H., Botermans A., Hoogendijk J.L., Henneman A.A., Deelder A.M., Spaink H.P. & Palmblad M. (2014), Identifying proteins in zebrafish embryos using spectral libraries generated from dissected adult organs and tissues, Journal of Proteome Research 13(3): 1537-1544.
- Meijer A.H. & Van der Vaart M. (2014), DRAM1 promotes the targeting of mycobacteria to selective autophagy, Autophagy : .
- Veneman W.J., Marín-Juez R., De Sonneville J., Ordas A., Jong-Raadsen S., Meijer A.H. & Spaink H.P. (2014), Establishment and optimization of a high throughput setup to study Staphylococcus epidermis and Mycobacterium marinum infection as a model for drug discovery, Journal of visualized experiments 88: e51649.
- Vaart M. van der, Korbee C.J., Lamers G.E.M., Tengeler A.C., Hosseini R., Haks M.C., Ottenhoff T.H.M., Spaink H.P. & Meijer A.H. (2014), Correction to: The DNA Damage-Regulated Autophagy Modulator DRAM1 Links Mycobacterial Recognition via TLR-MYD88 to Autophagic Defense, Cell Host & Microbe 16(1): 141-141.
- Torraca V., Masud S., Spaink H.P. & Meijer A.H. (2014), Macrophage-pathogen interactions in infectious diseases: new therapeutic insights from the zebrafish host model, Disease Models & Mechanisms 7(7): 785-797.
- Spaink H.P., Ottenhoff T.H.M., Dirks R.P. & Meijer A.H. (2014), New high-throughput technologies for drug screening in animal models of TB. In: Spaink H.P., Ottenhoff T.H.M., Dirks R.P. & Meijer A.H. (Eds.), The art & science of tuberculosis vaccine development. Selangor Darul Ehsan, Malaysia: Oxford University Press. 545-557.
- Kanwal Z., Wiegertjes G.F., Veneman W.J., Meijer A.H. & Spaink H.P. (2014), Comparative studies of Toll-like receptor signalling using zebrafish, Developmental and Comparative Immunology 46(1): 35-52.
- Vaart M. van der, Korbee C.J., Lamers G.E.M., Tengeler A.C., Hosseini R., Haks M.C., Ottenhoff T.H.M., Spaink H.P. & Meijer A.H. (2014), The DNA Damage-Regulated Autophagy Modulator DRAM1 Links Mycobacterial Recognition via TLR-MYD88 to Autophagic Defense, Cell Host & Microbe 15(6): 753-767.
- Benard E.L., Roobol S.J., Spaink H.P. & Meijer A.H. (2014), Phagocytosis of mycobacteria by zebrafish macrophages is dependent on the scavenger receptor Marco, a key control factor of pro-inflammatory signalling, Developmental and Comparative Immunology 47(2): 223-233.
- Fenaroli F., Westmoreland D., Benjaminsen J., Kolstad T., Skjeldal F.M., Meijer A.H., Van der Vaart M., Ulanova L., Roos N., Nyström B., Hildahl J. & Griffiths G. (2014), Nanoparticles as Drug Delivery System against Tuberculosis in Zebrafish Embryos, ACS Nano 8: 7014-26.
- Palmblad M., Henkel C.V., Dirks R.P., Meijer A.H., Deelder A.M. & Spaink H.P. (2013), Parallel deep transcriptome and proteome analysis of zebrafish larvae, BMC Research Notes 6: 428.
- Spaink H.P., Cui C., Wiweger M.I., Jansen H.J., Veneman W.J., Marin-Juez R., Sonneville J. de, Ordas A.K., Torraca V., Ent W. van der, Leenders W.P., Meijer A.H., Snaar-Jagalska B.E. & Dirks R.P.H. (2013), Robotic injection of zebrafish embryos for high-throughput screening in disease models, Methods 62(3): 246-254.
- Ordas A.K., Kanwal Z., Lindenberg V., Rougeot J.J.Y., Mink M., Spaink H.P. & Meijer A.H. (2013), MicroRNA-146 function in the innate immune transcriptome response of zebrafish embryos to Salmonella typhimurium infection, BMC Genomics 14: 696.
- Veneman W.J., Stockhammer O.W., Boer L. de, Zaat S.A., Meijer A.H. & Spaink H.P. (2013), A zebrafish high throughput screening system used for Staphylococcus epidermidis infection marker discovery, BMC Genomics 14: 255.
- Elks P.M., Brizee S., Van der Vaart M., Walmsley S.R., Van Eeden F., Renshaw S.A. & Meijer A.H. (2013), Hypoxia inducible factor signaling modulates susceptibility to mycobacterial infection via a nitric oxide dependent mechanism, PLoS Pathogens (9:e1003789): .
- Laroche F.J.F., Tulotta C., Lamers G.E.M., Stougaard J., Blaise M., Verbeek F.J., Yang P., Bustos M., Meijer A.H. & Spaink H.P. (2013), The embryonic expression patterns of zebrafish genes encoding LysM-domains, Gene Expression Patterns 13(7): 212-224.
- Kanwal Z., Zakrzewska A., Den Hertog J., Spaink H.P., Schaaf M.J. & Meijer A.H. (2013), Deficiency in hematopoietic phosphatase Ptpn6/Shp1 hyperactivates the innate immune system and impairs control of bacterial infections in zebrafish embryos, Journal of Immunology 190(4): 1631-1645.
- Vaart M. van der, Soest J.J. van, Spaink H.P. & Meijer A.H. (2013), Functional analysis of a zebrafish myd88 mutant identifies key transcriptional components of the innate immune system, Disease Models & Mechanisms 6(3): 841-854.
- Zhao J., Lambert G., Meijer A.H. & Rosa F.M. (2013), The Vox transcription factor represses endoderm development by interacting with Casanova and Pou2/Pou5f1/0ct3/Oct4, Development 140(1090-1099): .
- Heijer G.J. den, Putten P.W.H. van der, Benard E.L., Meijer A.H. & Verbeek F.J. (2012), Explorations in Texture Based Classification for Bacterial Infection in Zebrafish. Baets B. de, Manderick B., Rademaker M. & Waegeman W. (Eds.), BeneLearn 2012 : proceedings of the 21st Belgian-Dutch conference on machine learning. 21st Belgian-Dutch conference on Machine Learning (BeneLearn 2012) 24 May 2012 - 25 May 2012 13-18.
- Vaart M. van der, Spaink H.P. & Meijer A.H. (2012), Pathogen recognition and activation of the innate immune response in zebrafish, Advances in Hematology 2012: 159807.
- Zhang S., Haider I., Kohlen W., Jiang L., Bouwmeester H., Meijer A.H., Schluepmann H., Liu C.M. & Ouwerkerk P.B. (2012), Function of the HD-Zip I gene Oshox22 in ABA-mediated drought and salt tolerances in rice, 80: 571-585.
- Sharif F., Porta F., Meijer A.H., Kros A. & Richardson M.K. (2012), Mesoporous silica nanoparticles as a compound delivery system in zebrafish embryos, International Journal of Nanomedicine 2012(7): 1875-1890.
- Benard E.L., Sar A.M. van der, Ellett F., Lieschke G.J., Spaink H.P. & Meijer A.H. (2012), Infection of zebrafish embryos with intracellular bacterial pathogens, Journal of visualized experiments 61: e3781.
- Carvalho R.V., Davids W., Meijer A.H. & Verbeek F.J. (2012), Spatio-temporal Modeling and Simulation of Mycobacterium Pathogenesis Using Petri Nets. Hart E., Timmis J., Mitchell P., Nakamo T. & Dabiri F. (Eds.), Bio-Inspired Models of Networks, Information, and Computing Systems. BIONETICS 2011. . 6th International ICST Conference, BIONETICS 2011 5 December 2011 - 6 December 2011. Lecture Notes of the Institute of Computer Sciences, Social Informatics and Telecommunications Engineering no. 103. Berlin, Heidelberg: Springer. 236-241.
- He S., Lamers G.E.M., Beenakker J.W.M., Cui C., Ghotra V.P., Danen E.H.J., Meijer A.H., Spaink H.P. & Snaar-Jagalska B.E. (2012), Neutrophil-mediated experimental metastasis is enhanced by VEGFR inhibition in a zebrafish xenograft model, Journal of Pathology 227(4): 431-452.
- Meijer A.H. (Ed.) (2012), . BMC Genomics.
- Viana de Carvalho R., Kleijn H.C.M., Meijer A.H. & Verbeek F.J. (2012), Modeling innate immune response to early mycobacterium infection, Computational and Mathematical Methods in Medicine 2012: 790482.
- Peng K., Tomatsu I., Broek B. van den, Cui C., Korobko A.V., Noort J. van, Meijer A.H., Spaink H.P. & Kros A. (2011), Dextran based photodegradable hydrogels formed via a Michael addition, Soft Matter 7: 4881-4887.
- Meijer A.H. (Ed.) (2011), . Onbekend.
- Soest J.J. van, Stockhammer O.W., Ordas A., Bloemberg G.V., Spaink H.P. & Meijer A.H. (2011), Comparison of static immersion and intravenous injection systems for exposure of zebrafish embryos to the natural pathogen Edwardsiella tarda, BMC Immunology 12: 58.
- Carvalho R., Sonneville J. de, Stockhammer O.W., Savage N.D.L., Veneman W.J., Ottenhoff T.H.M., Dirks R.P., Meijer A.H. & Spaink H.P. (2011), A High-Throughput Screen for Tuberculosis Progression, PLoS ONE 6(2): e16779.
- Meijer A.H. & Spaink H.P. (2011), Host-pathogen interactions made transparent with the zebrafish model, Current Drug Targets 12(7): 1000-1017.
- Rotman J., Gils W. van, Butler D., Spaink H.P. & Meijer A.H. (2011), Rapid screening of innate immune gene expression in zebrafish using reverse transcription - multiplex ligation-dependent probe amplification, BMC Research Notes 4: 196.
- Ordas A., Hegedus Z., Henkel C.V., Stockhammer O.W., Butler D., Jansen H.J., Racz P.I., Mink M., Spaink H.P. & Meijer A.H. (2011), Deep sequencing of the innate immune transcriptomic response of zebrafish embryos to Salmonella infection, Onbekend 31: 716-724.
- Ouwerkerk P.B.F. & Meijer A.H. (2011), Yeast One-Hybrid Screens for Detection of Transcription, Methods in Molecular Biology 678: 211-227.
- Cui C., Benard E.L., Kanwal Z., Stockhammer O.W., Vaart M. van der, Zakrzewska A., Spaink H.P. & Meijer A.H. (2011), Infectious disease modeling and innate immune function in zebrafish embryos, Methods in Cell Biology 105: 273-308.
- Zakrzewska A., Cui C., Stockhammer O.W., Benard E.L., Spaink H.P. & Meijer A.H. (2010), Macrophage-specific gene functions in Spi1-directed innate immunity, Blood 116: e1-11.
- Vergunst A.C., Meijer A.H., Renshaw S.A. & O'Callaghan D. (2010), Burkholderia cenocepacia creates an intra-macrophage replication niche in zebrafish embryos, followed by bacterial dissemination and establishment of systemic infection, infection and immunology 78: 1495-1508.
- Ordas A., Hegedus Z., Henkel C.V., Stockhammer O.W., Butler D., Jansen H.J., Racz P.I., Mink M., Spaink H.P. & Meijer A.H. (2010), Deep sequencing of the innate immune transcriptomic response of zebrafish embryos to Salmonella infection, Fish and Shellfish Immunology 31(5): 716-724.
- Stockhammer O.W., Rauwerda H., Wittink F.R., Breit T.M., Meijer A.H. & Spaink H.P. (2010), Transcriptome analysis of Traf6 function in the innate immune response of zebrafish embryos, Mol.Immunol. 48: 179-190.
- Peng K., Cui C., Tomatsu I., Porta F., Meijer A.H., Spaink H.P. & Kros A. (2010), Cyclodextrin/dextran based drug carriers for a controlled release of hydrophobic drugs in zebrafish embryos, Soft Matter 6(16): 3778-3783.
- Brittijn S.A., Duivesteijn S.J., Belmamoune M., Bertens L.M.F., Bitter W., De Bruijn J.D., Champagne D.L., Cuppen E., Flik G., Van den Broucke-Grauls C.M., Janssen R., De Jong I.E.M., De Kloet E.R., Kros A., Meijer A., Metz J.R., Van der Sar A.M., Schaaf M.J., Schulte-Merker S., Spaink H.P., Tak P.P., Verbeek F.J., Vervoordeldonk M.J., Vonk F., Witte F., Yuan H. & Richardson M.K. (2009), Zebrafish development and regeneration: new tools for biomedical research, International Journal of Developmental Biology 53(5-6): 835-850.
- Webb K.J., Norton W.H., Trümbach D., Meijer A.H., Ninkovic J., Topp S., Heck D., Marr C., Wurst W., Theis F.J., Spaink H.P. & Bally-Cuif L. (2009), Zebrafish reward mutants reveal novel transcripts mediating the behavioral effects of amphetamine, Genome Biology 10: R81.
- Hegedűs Z., Zakrzewska A., Agoston V.C., Ordas A., Rácz P., Mink M., Spaink H.P. & Meijer A.H. (2009), Deep sequencing of the zebrafish transcriptome response to mycobacterium infection, Molecular Immunology 46(15): 2918-2930.
- Sar A.M. van der, Spaink H.P., Zakrzewska A., Bitter W. & Meijer A.H. (2009), Specificity of the zebrafish host transcriptome response to acute and chronic mycobacterial infection and the role of innate and adaptive immune components, Molecular Immunology 46(11-12): 2317-2332.
- Staneloni R.J., Rodriguez-Batiller M.J., Legisa D., Scarpin M.R., Cerdan P.D., Agalou A., Meijer A.H., Ouwerkerk P.B.F. & Casal J.J. (2009), Bell-like homeodomain selectively regulates the high-irradiance response of phytochrome A, Proc. Natl. Acad. Sci. 106: 13624-13629.
- Meijer A.H. (2009), Zebravissen bij het ontrafelen van het immuunsysteem. In: , Natuurkundige Voordrachten; Jaarboek van De Koninklijke Maatschappij voor Natuurkunde ‘Diligentia’.
- Ouwerkerk P.B.F. & Meijer A.H. (2009), Yeast one-hybrid screens for detection of transcription factor DNA interactions, Methods in Molecular Biology : .
- Mione M., Meijer A.H., Snaar-Jagalska B.E., Spaink H.P. & Trede N.S. (2009), Disease modeling in zebrafish: cancer and immune responses. second international workshop on Zebrafish Models of Cancer and the Immune Response 20 July 2009 - 22 July 2009. Zebrafish 445-451.
- Stockhammer O.W., Zakrzewska A., Hegedûs Z., Spaink H.P. & Meijer A.H. (2009), Transcriptome profiling and functional analyses of the zebrafish embryonic innate immune response to Salmonella infection, J. Immunol. 182: 5641-5653.
- Agalou A., Purwantomo S., Overnäs E., Johannesson H., Zhu X., Estiati A., Kam R.J. de, Engström P., Slamet-Loedin I.H., Zhu Z., Wang M., Xiong L., Meijer A.H. & Ouwerkerk P.B.F. (2008), A genome-wide survey of HD-Zip genes in rice and analysis of drought-responsive family members, 66: 87-103.
- Meijer A.H., Sar A.M. van der, Cunha C., Lamers G.E.M., Laplante M.A., Kikuta H., Bitter W., Becker T.S. & Spaink H.P. (2008), Identification and real-time imaging of a myc-expressing neutrophil population during inflammation and mycobacterial granuloma formation in zebrafish, Developmental and Comparative Immunology 32(1): 36-49.
- Schaaf M.J.M., Champagne D., Laanen I.H. van, Wijk D.C. van, Meijer A.H., Meijer O.C., Spaink H.P. & Richardson M.K. (2008), Discovery of a functional glucocorticoid receptor {beta}-isoform in zebrafish, Endocrinology 149(4): 1591-1599.
- Krens S.F.G., He S., Lamers G.E.M., Meijer A.H., Bakkers J., Schmidt T., Spaink H.P. & Snaar-Jagalska B.E. (2008), Distinct functions for ERK1 and ERK2 in cell migration processes during zebrafish gastrulation, Developmental Biology 319(2): 370-383.
- Trede N., Meijer A.H., Snaar-Jagalska B.E. & Spaink H.P. (2007), Model systems for infectious disease and cancer in zebrafish, EMBO workshop. EMBO Workshop 16 July 2007 - 18 July 2007. Zebrafish 287-292.
- Purwantomo S., Mulyaningsih E.S., Nugroho S., Estiati A., Slamet-Loedin I.H., Meijer A.H. & Ouwerkerk P.B.F. (2007), Transgenic breeding for drought tolerance and blast resistance in rice. Löffler H. & Syamsu K. (Eds.), Proceedings symposium on application of plant biotechnology for agribusiness. . Bogor, Indonesia: IBP Press. 11-24.
- Sar A.M. van der, Stockhammer O.W., Laan C. van der, Spaink H.P., Bitter W. & Meijer A.H. (2006), MyD88 innate immune function in a zebrafish embryo infection model, Infection and Immunity 74(4): 2436-2441.
- Welten M.C.M., Haan S.B. de, Boogert N. van den, Noordermeer J.N., Lamers G.E.M., Spaink H.P., Meijer A.H. & Verbeek F.J. (2006), ZebraFISH: fluorescent in situ hybridization protocol and three-dimensional imaging of gene expression patterns, Zebrafish 3(4): 465-474.
- Spaink H.P., Snaar-Jagalska B.E. & Meijer A.H. (2006), The innate immune system of vertebrates: challenges for future research. In: Sanchez F., Quinto C., Lopez-Lara I.M. & Geiger O. (Eds.), Biology of Plant-Microbe Interactions. St.Paul: I.S. for Molecular Plant-Microbe Interactions. 674-680.
- Deng X., Phillips J., Bräutigam A., Engelström P., Johannesson H., Meijer A.H., Ouwerkerk P.B.F., Ruberti I., Salinas J., Vera P., Iannacone R. & Bartels D. (2006), A homeodomain leucine zipper gene from Craterostigma plantagineum regulates abscisic acid responsive gene expression and physiological responses, 61: 469-489.
- He S., Salas-Vidal E., Rueb S., Krens S.F.G., Meijer A.H., Snaar-Jagalska B.E. & Spaink H.P. (2006), Genetic and transcriptome characterization of model zebrafish cell lines, Zebrafish 3(4): 441-453.
- Deng X., Phillips J., Brautigam A., Engstrom P., Johannesson H., Ouwerkerk P.B.F., Ruberti I., Salinas J., Vera P., Iannacone R., Meijer A.H. & Bartels D. (2006), A homeodomain leucine zipper gene from Craterostigma plantagineum regulates abscisic acid responsive gene expression and physiological responses, 61: 469-489.
- Enckevort E.J.G., Droc G., Piffanelli P., Greco R., Gagneur C., Weber C., González V.M., Cabot P., Fornara F., Berri S., Miro B., Lan P., Rafel M., Capell T., Puigdomènech P., Ouwekerk P.B.F., Meijer A.H., Pe' E., Colombo L., Christou P., Guiderdoni E. & Pereira A. (2005), EU-OSTID: European Oryza sativa Transposon Insertional Database, 59: 99-110.
- Canto-Canche B.B., Meijer A.H., Collu G., Verpoorte R. & Loyola-Vargas V.M. (2005), Characterization of a polyclonal antiserum against the monoterpene monooxygenase, geraniol 10-hydroxylase from Catharanthus roseus, Journal of Plant Physiology 162: 393-402.
- Welten M.C.M., Verbeek F.J., Meijer A.H. & Richardson M.K. (2005), Gene expression and digit homology in the chicken embryo wing, Evolution and Development 7(1): 18-28.
- Salas-Vidal E., Meijer A.H., Cheng X. & Spaink H.P. (2005), Genomic annotation and expression analysis of the zebrafish Rho small GTPase family during development and bacterial infection, Genomics 86(1): 25-37.
- Scarpella E., Simons E.J. & Meijer A.H. (2005), Multiple regulatory elements contribute to the vascular-specific expression of the rice HD-Zip gene Oshox1 in Arabidopsis, Plant and Cell Physiology 46: 1400-1410.
- Meijer A.H., Verbeek F.J., Salas-Vidal E., Corredor-Adamez M., Bussman J., Sar A.M. van der, Otto G.W., Geisler R. & Spaink H.P. (2005), Transcriptome profiling of adult zebrafish at the late stage of chronic tuberculosis due to Mycobacterium marinum infection, Molecular Immunology 42(10): 1185-1203.
- Corredor-Adamez M., Welten H.P., Spaink H.P., Jeffery J.E., Schoon R.T., Bakker M.A.G., Bagowski C.P., Meijer A.H., Verbeek F.J. & Richardson M.K. (2005), Genomic annotation and transcriptome analysis of the zebrafish (Danio rerio) hox complex with description of a novel member, Evolution and Development 7(5): 362-375.
- Enckevoort L.E. van, Droc G., Piffanelli P., Greco R., Gagneur C., Weber C., Gonzalez V.M., Cabot P., Fornara F., Berri S., Miro B., Lan P., Rafel M., Capelli T., Puigdomenec P., Ouwerkerk P.B.F., Meijer A.H., Pe E., Colombo L., Christou P., Guiderdoni E. & Pereira A. (2005), EU-OSTID: A collection of transposon insertional mutants for functional genomics in rice, 59: 99-110.
- Kuijt S.J.H., Lamer G.E.M., Rueb S., Scarpella E., Ouwerkerk P.B.F., Spaink H.P. & Meijer A.H. (2004), Different subcellular localization and trafficking properties of KNOX class 1 homeodomain proteins from rice, Plant Molecular Biology 55(6): 781-796.
- Scarpella E. & Meijer A.H. (2004), Pattern formation in the vascular system of monocot and dicot plant species, New Phytologist 164: 209-242.
- Meijer A.H., Krens S.F.G., Medina Rodriguez I.A., He S., Bitter W., Snaar-Jagalska B.E. & Spaink H.P. (2004), Expression analysis of the Toll-like receptor and TIR domain adaptor families of zebrafish, Molecular Immunology 40(11): 773-783.
- Greco R., Ouwerkerk P.B.F., Taal A.J., Sallaud C., Guiderdoni E., Meijer A.H., Hoge J.H.C. & Pereira A. (2004), Transcription and somatic transposition of the maize En / Spm transposon system in rice, Molecular Genet. Genomics 270: 514-523.
- Greco R., Ouwerkerk P.B.F., Kam R.J. de, Sallaud C., Favalli C., Colombo L., Guiderdoni E., Meijer A.H., Hoge J.H.C. & Pereira A. (2003), Transpositional behaviour of an Ac/Ds system for reverse genetics in rice, Theoretical and Applied Genetics 108: 10-24.
- Scarpella E., Rueb S. & Meijer A.H. (2003), The RADICLELESS1 gene is required for vascular pattern formation in rice, Development 130: 645-658.
- Scarpella E., Boot C.J.M., Rueb S. & Meijer A.H. (2002), The procambium specification gene Oshol 1 promotes polar auxin transport capacity and reduces its sensitivity toward inhibition, 130: 1349-1360.
- Postma-Haarsma A.D., Rueb S., Scarpella E., Besten P. den, Hoge J.H.C. & Meijer A.H. (2002), Developmental regulation and downstream effects of the knox class homeobox genes Oskn2 and Oskn3 from rice, 48: 423-441.
- Deng X., Philips J., Meijer A.H., Salamini F. & Bartels D. (2002), Characterization of five novel dehydration-responsive homeodomain leucine zipper genes from the resurrection plant Craterostigma plantagineum, 49: 601-610.
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- Postma-Haarsma A.D., Verwoert I.I.G.S., Stronk O.P., Koster J., Lamers G.E.M., Hoge J.H.C. & Meijer A.H. (1999), Characterization of the KNOX class homeobox genes Oskn2 and Oskn3 identified in a collection of cDNA libraries covering the early stages of rice embryogenesis, Plant Molecular Biology 39: 257-271.
- Meijer A.H., Ouwerkerk P.B.F. & Hoge J.H.C. (1998), Vectors for transcripton factor isolation and target gene identificaton by means of genetic selection in yeast, Yeast 14: 23-34.
- Meijer A.H., Kam R.J. de, Qin L. & Hoge J.H.C. (1998), A rice homolog of the human JAB1 transcriptional coactivator, 117: 152-153.
- Wang M., Oppedijk B.J., Caspers M.P.M., Lamers G.E.M., Boot M.J., Geerlings D.N.G., Bakhuizen B., Meijer A.H. & Duijn B. van (1998), Spatial and temporal regulation of DNA fragmentation in the aleurone of germinating barley, Journal of Experimental Botany 49(325): 1293-1301.