Universiteit Leiden

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Proefschrift

Design of selective inhibitors for human immunoproteasomes

The thesis describes the development, synthesis and biological evaluation of several proteasome inhibitor designs. Mainly, this work focusses on designing proteasome inhibitors that selectively inhibit the immunoproteasome, while leaving the constitutive proteasome mostly, if not completely, untouched.

Auteur
P.M. Dekker
Datum
28 november 2024
Links
Thesis in Leiden Repository
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