Dissertation
Design of selective inhibitors for human immunoproteasomes
The thesis describes the development, synthesis and biological evaluation of several proteasome inhibitor designs. Mainly, this work focusses on designing proteasome inhibitors that selectively inhibit the immunoproteasome, while leaving the constitutive proteasome mostly, if not completely, untouched.
- Author
- P.M. Dekker
- Date
- 28 November 2024
- Links
- Thesis in Leiden Repository
