Paulus Quax
Hoogleraar Experimentele Vasculaire Geneeskunde
- Naam
- Prof.dr. P.H.A. Quax
- Telefoon
- +31 71 526 1584
- p.h.a.quax@lumc.nl
- ORCID iD
- 0000-0002-6853-5760
Paul Quax is Professor in Experimentele Vasculaire Geneeskunde met speciale aandacht voor Experimentele Vasculaire Chirurgie. Hij is bestuurslid (penningmeester) van "Leiden Vascular Medicine" en de Dutch Atherosclerosis Society. Daarnaast is hij coordinator van het coschapblok wetenschapsstage voor de master Geneeskunde bij het LUMC. Hij is "Established Investigator" van de Nederlandse Hartstichting en Fellow van de American Heart Association (FAHA).
Paul Quax is Professor in Experimentele Vasculaire Geneeskunde met speciale aandacht voor Experimentele Vasculaire Chirurgie. Hij is bestuurslid (penningmeester) van "Leiden Vascular Medicine" en de Dutch Atherosclerosis Society. Daarnaast is hij coordinator van het coschapblok wetenschapsstage voor de master Geneeskunde bij het LUMC. Hij is "Established Investigator" van de Nederlandse Hartstichting en Fellow van de American Heart Association (FAHA).
Experimentele Vasculaire Geneeskunde
Bloedvaten en vaatwandcellen spelen een belangrijke rol bij vele pathofysiologische processen, niet alleen bij atherosclerose, maar ook bij restenose, bypass chirurgie, neovascularisatie, angiogenese, wondgenezing, of bij complicaties bij diabetes type-2. Een bloedvat is meer dan een buis waar bloed door stroomt, het is een complex orgaan met vele functies waarin meerdere celtypes nauw samenwerken op een manier die we maar beperkt begrijpen. Mijn onderzoek is er op gericht om meer inzicht te krijgen in de vasculaire biologie, de pathofysiologishe processen in de vaatwand en processen betrokken bij vasculaire remodeling. Met als doel onze kennis over het functioneren van de vaatwand te vergroten, ten einde gerichte therapeutische interventies te ontwikkelen. In dit translationeel onderzoek is een intensieve en goede samenwerking tussen de pre-klinische en klinische onderzoekers een belangrijke voorwaarde voor succes om de vindingen uit het laboratorium te vertalen naar nieuwe therapeutische mogelijkheden en om deze in de kliniek te kunnen implementeren.
Wetenschappelijke carrière
- Benoeming: 1 maart 2007:
- 1986 : Biologie, Radboud Universiteit,
- 21 maart 1991 : Promotie , Universiteit Leiden, titel proefschrift : Plasminogen activation, extracellular proteolysis and cancer.
- 20 juni 2008: Oratie , titel : Sleutelen aan Vaten
Prijzen een eervolle benoemingen
Prof.dr. P.H.A. Quax is "Established Investigator" van de Nederlandse Hartstichting en Fellow van de American Heart Association (FAHA)
Volg P.H.A. Quax
LinkedIn |Orcid | ResearchGate | Einthovenlaboratory | Hartlongcentrum
Hoogleraar Experimentele Vasculaire Geneeskunde
- Faculteit Geneeskunde
- LUMC - Medische Faculteit Leiden
- Divisie 1
- Heelkunde
- Florijn, B.W.; Bent, M.L. van der; Nguyen, T.M.T.; Quax, P.H.A.; Wermer, M.J.H.; Nossent, A.Y. & Kruyt, N.D. (2023), Non-coding RNAs versus protein biomarkers to diagnose and differentiate acute stroke: Systematic review and meta-analysis, Journal of Stroke & Cerebrovascular Diseases 32(11).
- Saenz-Pipaon, G.; Jover, E.; Bent, M.L. van der; Orbe, J.; Rodriguez, J.A.; Fernández-Celis, A.; Quax, P.H.A.; Paramo, J.A.; López-Andrés, N.; Martín-Ventura, J.L.; Yaël-Nossent, A. & Roncal, C. (2023), Role of LCN2 in a murine model of hindlimb ischemia and in peripheral artery disease patients, and its potential regulation by miR-138-5P, Atherosclerosis 385.
- Peeters, J.A.H.M.; Peters, H.A.B.; Videler, A.J.; Hamming, J.F.; Schepers, A. & Quax, P.H.A. (2023), Exploring the Effects of Human Bone Marrow-Derived Mononuclear Cells on Angiogenesis In Vitro, International Journal of Molecular Sciences 24(18).
- Sier, V.Q.; Jong, A. de; Quax, P.H.A. & Vries, M.R. de (2022), Visualization of Murine Vascular Remodeling and Blood Flow Dynamics by Ultra-High-Frequency Ultrasound Imaging, International Journal of Molecular Sciences 23(21).
- Bezhaeva, T.; Karper, J.; Quax, P.H.A. & Vries, M.R. de (2022), The Intriguing Role of TLR Accessory Molecules in Cardiovascular Health and Disease, Frontiers in Cardiovascular Medicine 9.
- Depuydt, M.A.C.; Smit, V.; Vigario, F.L.; Kleijn, M.N.A.B.; Vries, M.R. de; Quax, P.H.A.; Wezel, A.; Smeets, H.J.; Kuiper, J.; Foks, A.C.; Bot, I. & Slutter, B. (2022), Granzyme B+CD4+T cells associate with an unstable plaque phenotype in advanced human atherosclerosis, Cardiovascular Research 118(SUPPL 1).
- Jong, A. de; Sier, V.Q.; Peters, H.A.B.; Schilder, N.K.M.; Jukema, J.W.; Goumans, M.J.T.H.; Quax, P.H.A. & Vries, M.R. de (2022), Interfering in the ALK1 pathway results in macrophage-driven outward remodeling of murine vein grafts, Frontiers in Cardiovascular Medicine 8.
- Depuydt, M.A.C.; Smit, V.; Vigario, F.; Kleijn, M.N.A.B.; Vries, M.R. de; Quax, P.H.A.; Wezel, A.; Smeets, H.J.; Kuiper, J.; Foks, A.C.; Bot, I. & Slutter, B. (2022), GRANZYME B+CD4+T CELLS ASSOCIATE WITH AN UNSTABLE PLAQUE PHENOTYPE IN ADVANCED HUMAN ATHEROSCLEROSIS, Atherosclerosis 355: E9-E9.
- Brinks, J.; Dijk, E.H.C. van; Kielbasa, S.M.; Mei, H.L.; Veen, I. van der; Peters, H.A.B.; Sips, H.C.M.; Notenboom, R.G.E.; Quax, P.H.A.; Boon, C.J.F. & Meijer, O.C. (2022), The Cortisol Response of Male and Female Choroidal Endothelial Cells: Implications for Central Serous Chorioretinopathy, The Journal of Clinical Endocrinology & Metabolism 107(2): 512-524.
- Fernandes, H.; Zonnari, A.; Abreu, R.; Aday, S.; Barao, M.; Albino, I.; Lino, M.; Branco, A.; Seabra, C.; Barata, T.; Leal, E.C.; Tralhao, J.G.; Goncalves, L.; Jong, A. de; Peters, H.A.B.; Vries, M.R. de; Martins, P.D.; Quax, P.H.A. & Ferreira, L. (2022), Extracellular vesicles enriched with an endothelial cell pro-survival microRNA affects skin tissue regeneration, Molecular Therapy - Nucleic Acids 28: 307-327.
- Brinks, J.; Dijk, E.H.C. van; Klaassen, I.; Schlingemann, R.O.; Kielbasa, S.M.; Emri, E.; Quax, P.H.A.; Bergen, A.A.; Meijer, O.C. & Boon, C.J.F. (2022), Exploring the choroidal vascular labyrinth and its molecular and structural roles in health and disease, Progress in Retinal and Eye Research 87.
- Ewing, M.; Karper, J.C.; Vries, M.R. de & Quax, P.H.A. (2022), Editorial: Inflammation and immunomodulation in cardiovascular remodeling, Frontiers in Cardiovascular Medicine 9.
- Baganha, F.; Sluiter, T.J.; Jong, R.C.M. de; Alst, L.A. van; Peters, H.A.B.; Jukema, J.W.; Delibegovic, M.; Pettersson, K.; Quax, P.H.A. & Vries, M.R. de (2022), Phosphorylcholine monoclonal antibody therapy decreases intraplaque angiogenesis and intraplaque hemorrhage in murine vein grafts, International Journal of Molecular Sciences 23(21).
- Jong, A. de; Sluiter, T.J.; Peters, H.A.B.; Jukema, W.J.; Quax, P.H.A. & Vries, M.R. de (2022), CO-STIMULATORY TREATMENT ENHANCES THE PROTECTIVE ROLE OF CD8 AND CD4 T CELLS IN MURINE VEIN GRAFTS, Atherosclerosis 355: E34-E34.
- Zhang, L.; Goossens, E.; Vries, M.R. de; Jukema, W.J.; Quax, P.H.A. & Nossent, Y. (2022), COLD-INDUCIBLE RNA-BINDING PROTEIN BUT NOT ITS ANTISENSE LNCRNA IS A DIRECT NEGATIVE REGULATOR OF ANGIOGENESIS VIA REGULATION OF THE 14Q32 ANGIO-MIRS-MICRORNA-329-3P AND MICRORNA-495-3P, Atherosclerosis 355: E350-E351.
- Homberg, D.A.L. van den; Kwast, R.V.C.T. van der; Quax, P.H.A. & Nossent, A.Y. (2022), N-6-methyladenosine in vasoactive microRNAs during hypoxia, International Journal of Molecular Sciences 23(3).
- Sluiter, T.J.; Tillie, R.; Leijgraaf, R. van de; Bruijn, J. de; Peters, H.A.B.; Quax, P.H.A.; Sluimer, J. & Vries, R. de (2022), MYELOID PHD2 CONDITIONAL KNOCK-OUT PROMOTES VEIN GRAFT PLAQUE STABILITY BY REDUCING VESSEL WALL M1 MACROPHAGES AND INTRAPLAQUE HAEMORRHAGE, Atherosclerosis 355: E32-E32.
- Woudenberg, T.; Kruyt, N.D.; Quax, P.H.A. & Nossent, A.Y. (2022), Change of heart , Current Heart Failure Reports 19(5): 255-266.
- Smolders, V.F.E.D.; Rodriguez, C.; Blanco, I.; Szulcek, R.; Timens, W.; Piccari, L.; Roger, Y.; Hu, X.; Moren, C.; Bonjoch, C.; Sebastian, L.; Castella, M.; Osorio, J.; Peinado, V.I.; Bogaard, H.J.; Quax, P.H.A.; Cascante, M.; Barbera, J.A. & Tura-Ceide, O. (2022), Metabolic profile in endothelial cells of chronic thromboembolic pulmonary hypertension and pulmonary arterial hypertension, Scientific Reports 12(1).
- Ingen, E. van; Engbers, P.A.M.; Woudenberg, T.; Bent, M.L. van der; Mei, H.L.; Wojta, J.; Quax, P.H.A. & Nossent, A.Y. (2022), C/D box snoRNA SNORD113-6 guides 2'-O- methylation and protects against site-specific fragmentation of tRNALeu(TAA) in vascular remodeling, Molecular Therapy - Nucleic Acids 30: 162-172.
- Ingen, E. van; Homberg, D.A.L. van den; Bent, M.L. van der; Mei, H.L.; Papac-Milicevic, N.; Kremer, V.; Boon, R.A.; Quax, P.H.A.; Wojta, J. & Nossent, A.Y. (2022), C/D box snoRNA SNORD113-6/AF357425 plays a dual role in integrin signalling and arterial fibroblast function via pre-mRNA processing and 2 ' O-ribose methylation, Human Molecular Genetics 31(7): 1051-1066.
- Garoffolo, G.; Cassanmagnago, G.C.; Thomas, A.T.; Vries, M.D.V. de; Ruiter, M.S.R.; Carrara, M.C.; Vono, R.V.; Saccu, C.S.; Agrifoglio, M.A.; Martelli, F.M.; Condorelli, G.C.; Madeddu, P.M.; Quax, P.H.A.Q.; Spinetti, G.S. & Pesce, M.P. (2022), Mechanical activation of Hippo/TGFb pathways lead human saphenous vein progenitors toward pro-fibrotic differentiation in aorto-coronary bypass failure, Cardiovascular Research 118(SUPPL 1).
- Bakker, W.; Dingenouts, C.K.E.; Lodder, K.; Wiesmeijer, K.C.; Jong, A. de; Kurakula, K.; Mager, H.J.J.; Smits, A.M.; Vries, M.R. de; Quax, P.H.A. & Goumans, M.J.T.H. (2021), BMP receptor inhibition enhances tissue repair in endoglin heterozygous mice, International Journal of Molecular Sciences 22(4).
- Sier, V.Q.; Vorst, J.R. van der; Quax, P.H.A.; Vries, M.R. de; Zonoobi, E.; Vahrmeijer, A.L.; Dekkers, I.A.; Geus-Oei, L.F. de; Smits, A.M.; Cai, W.B.; Sier, C.F.M.; Goumans, M.J.T.H. & Hawinkels, L.J.A.C. (2021), Endoglin/CD105-based imaging of cancer and cardiovascular diseases, International Journal of Molecular Sciences 22(9).
- Perrotta, P.; Vries, M.R. de; Peeters, B.; Guns, P.J.; Meyer, G.R.Y. de; Quax, P.H.A. & Martinet, W. (2021), PFKFB3 gene deletion in endothelial cells inhibits intraplaque angiogenesis and lesion formation in a murine model of venous bypass grafting, Angiogenesis 25.
- Hoven, P. van den; Goncalves, L.N.; Quax, P.H.A.; Rijswijk, C.S.P. van; Schaik, J. van; Schepers, A.; Vahrmeijer, A.L.; Hamming, J.F. & Vorst, J.R. van der (2021), Perfusion patterns in patients with chronic limb-threatening ischemia versus control patients using near-infrared fluorescence imaging with indocyanine green, Biomedicines 9(10).
- Brinks, J.; Dijk, E.H.C. van; Notenboom, R.G.E.; Quax, P.H.A.; Boon, C.J.F. & Meijer, O.C. (2021), Response to Letter to the Editor From Behar-Cohen et al.: The Cortisol Response of Male and Female Choroidal Endothelial Cells: Implications for Central Serous Chorioretinopathy, The Journal of Clinical Endocrinology & Metabolism.
- Sluiter, T.J.; Buul, J.D. van; Huveneers, S.; Quax, P.H.A. & Vries, M.R. de (2021), Endothelial barrier function and leukocyte transmigration in atherosclerosis, Biomedicines 9(4).
- Goossens, E.A.C.; Zhang, L.C.; Vries, M.R. de; Jukema, J.W.; Quax, P.H.A. & Nossent, A.Y. (2021), Cold-inducible RNA-binding protein but not its antisense lncRNA is a direct negative regulator of angiogenesis in vitro and in vivo via regulation of the 14q32 angiomiRs-microRNA-329-3p and microRNA-495-3p, International Journal of Molecular Sciences 22(23).
- Tura-Ceide, O.; Smolders, V.F.E.D.; Aventin, N.; Moren, C.; Guitart-Mampel, M.; Blanco, I.; Piccari, L.; Osorio, J.; Rodriguez, C.; Rigol, M.; Solanes, N.; Malandrino, A.; Kurakula, K.; Goumans, M.J.; Quax, P.H.A.; Peinado, V.I.; Castella, M. & Barbera, J.A. (2021), Derivation and characterisation of endothelial cells from patients with chronic thromboembolic pulmonary hypertension, Scientific Reports 11(1).
- Smolders, V.F.E.D.; Lodder, K.; Rodriguez, C.; Tura-Ceide, O.; Barbera, J.A.; Jukema, J.W.; Quax, P.H.A.; Goumans, M.J. & Kurakula, K. (2021), The inflammatory profile of CTEPH-derived endothelial cells is a possible driver of disease progression, Cells 10(4).
- Brinks, J.; Dijk, E.H.C. van; Kielbasa, S.M.; Mei, H.L.; Quax, P.H.A.; Meijer, O.C. & Boon, C.J.F. (2021), Genome-wide transcriptional responses of human choroidal endothelial cells to corticosteroids as a model for central serous chorioretinopathy, Acta Ophthalmologica 99: 33-33.
- Pluijmert, N.J.; Atsma, D.E. & Quax, P.H.A. (2021), Post-ischemic myocardial inflammatory response, Frontiers in Cardiovascular Medicine 8.
- Aref, Z. & Quax, P.H.A. (2021), In vivo matrigel plug assay as a potent method to investigate specific individual contribution of angiogenesis to blood flow recovery in mice, International Journal of Molecular Sciences 22(16).
- Saenz-Pipaon, G.; Bent, M.L. van der; Martinez-Aguilar, E.; Rodriguez, J.A.; Fernandez-Alonso, L.; Paramo, J.A.; Quax, P.H.A.; Orbe, J.; Nossent, A.Y. & Roncal, C. (2021), LCN2 REGULATION BY MIR-138-5P IN SKELETAL MUSCLE REGENERATION AFTER ISCHEMIA, Atherosclerosis 331: E221-E221.
- Brinks, J.; Dijk, E. van; Kielbasa, S.; Mei, H.L.; Quax, P.; Meijer, O. & Boon, C.J.F. (2021), Genome-wide transcriptional responses of human choroidal endothelial cells to corticosteroids as a model for central serous chorioretinopathy, Investigative Ophthalmology & Visual Science 62(8).
- Pluijmert, N.J.; Jong, R.C.M. de; Vries, M.R. de; Pettersson, K.; Atsma, D.E.; Jukema, J.W. & Quax, P.H.A. (2021), Phosphorylcholine antibodies restrict infarct size and left ventricular remodelling by attenuating the unreperfused post-ischaemic inflammatory response, Journal of Cellular and Molecular Medicine 25(16).
- Ingen, E. van; Foks, A.C.; Woudenberg, T.; Bent, M.L. van der; Jong, A. de; Hohensinner, P.J.; Wojta, J.; Bot, I.; Quax, P.H.A. & Nossent, A.Y. (2021), Inhibition of microRNA-494-3p activates Wnt signaling and reduces proinflammatory macrophage polarization in atherosclerosis, Molecular Therapy - Nucleic Acids 26: 1228-1239.
- Baganha, F.; Jong, R.C.M. de; Peters, E.A.; Voorham, W.; Jukema, J.W.; Delibegovic, M.; Vries, M.R. de & Quax, P.H.A. (2021), Atorvastatin pleiotropically decreases intraplaque angiogenesis and intraplaque haemorrhage by inhibiting ANGPT2 release and VE-Cadherin internalization, Angiogenesis 24(3): 567-581.
- Jong, A. de; Jong, R.C.M. de; Peters, E.A.; Arens, R.; Jukema, J.W.; Vries, M.R. de & Quax, P.H.A. (2021), P300/CBP associated factor (PCAF) deficiency enhances diet-induced atherosclerosis in ApoE3*Leiden mice via systemic inhibition of regulatory T cells, Frontiers in Cardiovascular Medicine 7.
- Vries, M.R.; Ewing, M.M.; Jong, R.C.M.; MacArthur, M.R.; Karper, J.C.; Peters, E.A.B.; Nordzell, M.; Karabina, S.A.P.; Sexton, D.; Dahlbom, I.; Bergman, A.; Mitchell, J.R.; Frostegard, J.; Kuiper, J.; Ninio, E.; Jukema, J.W.; Pettersson, K. & Quax, P.H.A. (2021), Identification of IgG1 isotype phosphorylcholine antibodies for the treatment of inflammatory cardiovascular diseases, Journal of Internal Medicine 290(1).
- Kurakula, K.; Smolders, V.F.E.D.; Tura-Ceide, O.; Jukema, J.W.; Quax, P.H.A. & Goumans, M.J. (2021), Endothelial dysfunction in pulmonary hypertension: cause or consequence?, Biomedicines 9(1).
- Nguyen, T.T.M.; Bent, M.L. van der; Wermer, M.J.H.; Wijngaard, I.R. van den; Zwet, E.W. van; Groot, B. de; Quax, P.H.A.; Kruyt, N.D. & Nossent, A.Y. (2021), Circulating tRNA fragments as a novel biomarker class to distinguish acute stroke subtypes, International Journal of Molecular Sciences 22(1).
- Pluijmert, N.J.; Bart, C.I.; Bax, W.H.; Quax, P.H.A. & Atsma, D.E. (2020), Effects on cardiac function, remodeling and inflammation following myocardial ischemia-reperfusion injury or unreperfused myocardial infarction in hypercholesterolemic APOE*3-Leiden mice, Scientific Reports 10(1).
- Brinks, J.; Dijk, E.H.C. van; Kielbasa, S.M.; Mei, H.; Quax, P.H.A.; Meijer, O.C. & Boon, C.J.F. (2020), Transcriptional responses to cortisol in primary human endothelial cells are not intrinsically sex-dependent, Acta Ophthalmologica 98: 41-41.
- Baart, V.M.; Houvast, R.D.; Geus-Oei, L.F. de; Quax, P.H.A.; Kuppen, P.J.K.; Vahrmeijer, A.L. & Sier, C.F.M. (2020), Molecular imaging of the urokinase plasminogen activator receptor: opportunities beyond cancer, EJNMMI Research 10(1).
- Deindl, E. & Quax, P.H.A. (2020), Arteriogenesis and therapeutic angiogenesis in its multiple aspects, Cells 9(6).
- Perrotta, P.; Pintelon, I.; Vries, M.R. de; Quax, P.H.A.; Timmermans, J.P.; Meyer, G.R.Y. de & Martinet, W. (2020), Three-dimensional imaging of intraplaque neovascularization in a mouse model of advanced atherosclerosis, Journal of Vascular Research 57(6): 348-354.
- Stahle, M.; Silvola, J.M.U.; Hellberg, S.; Vries, M. de; Quax, P.H.A.; Kroon, J.; Rinne, P.; Jong, A. de; Liljenback, H.; Savisto, N.; Wickman, A.; Stroes, E.S.G.; Yla-Herttuala, S.; Saukko, P.; Abrahamsson, T.; Pettersson, K.; Knuuti, J.; Roivainen, A. & Saraste, A. (2020), Therapeutic antibody against phosphorylcholine preserves coronary function and attenuates vascular F-18-FDG uptake in atherosclerotic mice, JACC: Basic to Translational Science 5(4): 360-373.
- Pluijmert, N.J.; Jong, R.C.M. de; Vries, M.R. de; Pettersson, K.; Atsma, D.E.; Jukema, J.W. & Quax, P.H.A. (2020), Phosphorylcholine antibodies preserve cardiac function and reduce infarct size by attenuating the post-ischemic inflammatory response, JACC: Basic to Translational Science 5(12): 1228-1239.
- Kip, P.; Tao, M.; Trocha, K.M.; MacArthur, M.R.; Peters, H.A.B.; Mitchell, S.J.; Mann, C.G.; Sluiter, T.J.; Jung, J.N.; Patterson, S.; Quax, P.H.A.; Vries, M.R. de; Mitchell, J.R. & Ozaki, C.K. (2020), Periprocedural hydrogen sulfide therapy improves vascular remodeling and attenuates vein graft disease, Journal of the American Heart Association Cardiovascular and Cerebrovascular Disease 9(22).
- Bent, M.L. van der; Wijk, K. van; Cakir, C.; Duinen, S. van; Kroft, A. van der; Kruyt, N.; Quax, P. & Nossent, A.Y. (2020), INTRACRANIAL ATHEROSCLEROSIS: CELLULAR CONTENT, INFLAMMATORY PROFILES AND SPATIAL EXPRESSION OF MIRNA-494-3P, International Journal of Stroke 15(1_SUPPL): 474-475.
- Jong, A. de; Sier, V.Q.; Peters, H.A.B.; Jukema, J.W.; Goumans, M.J.; Quax, P.A.H. & Vries, M.R. de (2020), Inhibition of BMP9 and BMP10 signalling by the ALK1-Fc Ligand Trap enhances systemic inflammation and increases vein graft atherosclerosis, European Heart Journal 41: 3828-3828.
- Vries, M. de; Baganha, F.; Jong, R.C.M. de; Peters, H.A.B.; Petterson, K. & Quax, P.H.A. (2020), IgG1 phosphorylcholine ameliorates plaque stability via reduced intraplaque angiogenesis and intraplaque haemorrhage in a murine atherosclerosis model, European Heart Journal 41: 3650-3650.
- Pluijmert, N.J.; Bart, C.I.; Bax, W.H.; Quax, P.H.A. & Atsma, D.E. (2020), Effects on cardiac function, remodeling and inflammation following myocardial ischemia-reperfusion injury or unreperfused myocardial infarction in hypercholesterolemic APOE*3-Leiden mice, Scientific Reports 10(1).
- Smolders, V.F.E.D.; Rodriguez, C.; Moren, C.; Blanco, I.; Osorio, J.; Piccari, L.; Bonjoch, C.; Quax, P.H.A.; Peinado, V.I.; Castella, M.; Barbera, J.A.; Cascante, M. & Tura-Ceide, O. (2020), Decreased Glycolysis as Metabolic Fingerprint of Endothelial Cells in Chronic Thromboembolic Pulmonary Hypertension.
- Parma, L.; Peters, H.A.B.; Sluiter, T.J.; Simons, K.H.; Lazzari, P.; Vries, M.R. de & Quax, P.H.A. (2020), bFGF blockade reduces intraplaque angiogenesis and macrophage infiltration in atherosclerotic vein graft lesions in ApoE3*Leiden mice, Scientific Reports 10(1).
- Baganha, F.; Ritsma, L.; Quax, P.H.A. & Vries, M.R. de (2020), Assessment of microvessel permeability in murine atherosclerotic vein grafts using two-photon intravital microscopy, International Journal of Molecular Sciences 21(23).
- Kwast, R.V.C.T. van der; Parma, L.; Bent, M.L. van der; Ingen, E. van; Baganha, F.; Peters, H.A.B.; Goossens, E.A.C.; Simons, K.H.; Palmen, M.; Vries, M.R. de; Quax, P.H.A. & Nossent, A.Y. (2020), Adenosine-to-inosine editing of vasoactive microRNAs alters their targetome and function in ischemia, Molecular Therapy - Nucleic Acids 21: 932-953.
- Goossens, E.A.C.; Vries, M.R. de; Jukema, J.W.; Quax, P.H.A. & Nossent, A.Y. (2020), Myostatin inhibits vascular smooth muscle cell proliferation and local 14q32 microRNA expression, but not systemic inflammation or restenosis, International Journal of Molecular Sciences 21(10).
- Deindl, E. & Quax, P.H.A. (2020), From increased fluid shear stress to natural bypass growth, International Journal of Molecular Sciences 21(10).
- Parma, L.; Peters, H.A.B.; Johansson, M.E.; Gutierrez, S.; Meijerink, H.; Kimpe, S. de; Vries, M.R. de & Quax, P.H.A. (2020), Bis(maltolato)oxovanadium(IV) induces angiogenesis via phosphorylation of VEGFR2, International Journal of Molecular Sciences 21(13).
- Baganha, F.; Jong, A. de; Jukema, J.W.; Quax, P.H.A. & Vries, M.R. de (2020), The role of immunomodulation in vein graft remodeling and failure, Journal of Cardiovascular Translational Research 14.
- Trocha, K.M.; Kip, P.; Tao, M.; MacArthur, M.R.; Trevino-Villarreal, J.H.; Longchamp, A.; Toussaint, W.; Lambrecht, B.N.; Vries, M.R. de; Quax, P.H.A.; Mitchell, J.R. & Ozaki, C.K. (2020), Short-term preoperative protein restriction attenuates vein graft disease via induction of cystathionine gamma-lyase, Cardiovascular Research 116(2): 416-428.
- Parma, L.; Peters, H.A.B.; Baganha, F.; Sluimer, J.C.; Vries, M.R. de & Quax, P.H.A. (2020), Prolonged hyperoxygenation treatment improves vein graft patency and decreases macrophage content in atherosclerotic lesions in ApoE3*Leiden mice, Cells 9(2).
- Wang, G.Q.; Vries, M.R. de; Sol, W.M.P.J.; Oeveren-Rietdijk, A.M. van; Boer, H.C. de; Zonneveld, A.J. van; Quax, P.H.A.; Rabelink, T.J. & Berg, B.M. van den (2020), Loss of endothelial glycocalyx hyaluronan impairs endothelial stability and adaptive vascular remodeling after arterial ischemia, Cells 9(4).
- Bot, I.; Velden, D. van der; Bouwman, M.; Kroner, M.J.; Kuiper, J.; Quax, P.H.A. & Vries, M.R. de (2020), Local mast cell activation promotes neovascularization, Cells 9(3).
- Kwast, R.V.C.T. van der; Quax, P.H.A. & Nossent, A.Y. (2020), An emerging role for isomiRs and the microRNA epitranscriptome in neovascularization, Cells 9(1).
- Kwast, R.V.C.T. van der; Woudenberg, T.; Quax, P.H.A. & Nossent, A.Y. (2020), MicroRNA-411 and its 5 '-IsomiR have distinct targets and functions and are differentially regulated in the vasculature under ischemia, Molecular Therapy 28(1): 157-170.
- Vries, M.R. de; Parma, L.; Peters, H.A.B.; Schepers, A.; Hamming, J.F.; Jukema, J.W.; Goumans, M.J.T.H.; Guo, L.; Finn, A.V.; Virmani, R.; Ozaki, C.K. & Quax, P.H.A. (2019), Blockade of vascular endothelial growth factor receptor 2 inhibits intraplaque haemorrhage by normalization of plaque neovessels, Journal of Internal Medicine 285(1): 59-74.
- Smolders, V.F.; Zodda, E.; Quax, P.H.A.; Carini, M.; Barbera, J.A.; Thomson, T.M.; Tura-Ceide, O. & Cascante, M. (2019), Metabolic Alterations in Cardiopulmonary Vascular Dysfunction.
- Kip, P.; Tao, M.; Trocha, K.M.; MacArthur, M.R.; Mitchell, S.J.; Jung, J.; Quax, P.H.; Vries, M.R. de; Mitchell, J.R. & Ozaki, C.K. (2019), Short-term Methionine Restriction Protects from Vein Graft Disease via Perivascular Adipose Dependent Mechanisms, Arteriosclerosis, Thrombosis, and Vascular Biology 39.
- Kip, P.; Tao, M.; Trocha, K.M.; MacArthur, M.R.; Mitchell, S.J.; Patterson, S.; Jung, J.; Quax, P.H.; Vries, M.R. de; Mitchell, J.R. & Ozaki, C.K. (2019), Periprocedural hydrogen sulfide therapy impairs vascular remodeling and improves vein graft patency, Arteriosclerosis, Thrombosis, and Vascular Biology 39.
- Vries, M.R. de; Baganha, F.; Peters, E.A. & Quax, P.H. (2019), Atorvastatin inhibits plaque angiogenesis and induces neovessel maturation in murine vein grafts, Arteriosclerosis, Thrombosis, and Vascular Biology 39.
- Katiraei, S.; Vries, M.R. de; Costain, A.H.; Thiem, K.; Hoving, L.R.; Diepen, J.A. van; Smits, H.H.; Bouter, K.E.; Rensen, P.C.N.; Quax, P.H.A.; Nieuwdorp, M.; Netea, M.C.; Vos, W.M. de; Cani, P.D.; Belzer, C.; Dijk, K.W. van; Berbee, J.F.P. & Harmelen, V. van (2019), Akkermansia muciniphila Exerts Lipid-Lowering and Immunomodulatory Effects without Affecting Neointima Formation in Hyperlipidemic APOE*3-Leiden.CETP Mice, Molecular Nutrition and Food Research.
- Ingen, E. van; Foks, A.C.; Kroner, M.J.; Kuiper, J.; Quax, P.H.A.; Bot, I. & Nossent, A.Y. (2019), Antisense Oligonucleotide Inhibition of MicroRNA-494 Halts Atherosclerotic Plaque Progression and Promotes Plaque Stabilization, Molecular Therapy - Nucleic Acids 18: 638-649.
- Simons, K.H.; Vries, M.R. de; Peters, H.A.B.; Jukema, J.W.; Quax, P.H.A. & Arens, R. (2019), CD8+ T Cells Protect During Vein Graft Disease Development, Frontiers in Cardiovascular Medicine 6.
- Smolders VF, Rodriguez C, Blanco I, Osorio J, Piccari L, Bonjoch C, Quax PHA, Cascante M, Peinado VI, Castella M, Barbera JA & Tura-Ceide O (2019), Decreased glycolysis as metabolic footprint of endothelial cells in chronic thromboembolic pulmonary hypertension, European Respiratory Journal 54.
- Hoeven, B.L. van der; Pires, N.M.M.; Warda, H.M.; Putter, H.; Quax, P.H.A.; Schalij, M.J. & Jukema, J.W. (2019), Dexamethasone-eluting stents for the prevention of in-stent restenosis: Evidence for a differential effect in insulin-dependent and non-insulin-dependent diabetic patients (vol 124, pg 166, 2008), International Journal of Cardiology 287: 211-211.
- Perrotta, P.; Pintelon, I.; Vries, M. de; Timmermans, J.P.; Quax, P.; Meyer, G.R.Y. de & Martinet, W. (2019), D IMAGING OF INTRAPLAQUE NEOVASCULARIZATION IN TWO MOUSE MODELS OF ADVANCED ATHEROSCLEROSIS USING THREE-DIMENSIONAL IMAGING OF SOLVENT CLEARED ORGANS (IDISCO) TECHNOLOGY, Atherosclerosis 287: E96-E96.
- Kritikou, E.; Depuydt, M.A.C.; Vries, M.R. de; Mulder, K.E.; Govaert, A.M.; Smit, M.D.; Duijn, J. van; Foks, A.C.; Wezel, A.; Smeets, H.J.; Slutter, B.; Quax, P.H.A.; Kuiper, J. & Bot, I. (2019), Flow Cytometry-Based Characterization of Mast Cells in Human Atherosclerosis.
- Hakansson, K.E.J.; Goossens, E.A.C.; Trompet, S.; Ingen, E. van; Vries, M.R. de; Kwast, R.V.C.T. van der; Ripa, R.S.; Kastrup, J.; Hohensinner, P.J.; Kaun, C.; Wojta, J.; Bohringer, S.; Cessie, S. le; Jukema, J.W.; Quax, P.H.A. & Nossent, A.Y. (2019), Genetic associations and regulation of expression indicate an independent role for 14q32 snoRNAs in human cardiovascular disease, Cardiovascular Research 115(10): 1519-1532.
- Pluijmert, N.J.; Haan, M.C. den; Zuylen, V.L. van; Steendijk, P.; Boer, H.C. de; Zonneveld, A.J. van; Fibbe, W.E.; Schalij, M.J.; Quax, P.H.A. & Atsma, D.E. (2019), Hypercholesterolemia affects cardiac function, infarct size and inflammation in APOE*3-Leiden mice following myocardial ischemia-reperfusion injury, PLoS ONE 14(6).
- Simons, K.H.; Vries, M.R. de; Jong, R.C.M. de; Peters, H.A.B.; Jukema, J.W. & Quax, P.H.A. (2019), IRF3 and IRF7 mediate neovascularization via inflammatory cytokines.
- Goossens, E.A.C.; Vries, M.R. de; Simons, K.H.; Putter, H.; Quax, P.H.A. & Nossent, A.Y. (2019), miRMap: Profiling 14q32 microRNA Expression and DNA Methylation Throughout the Human Vasculature, Frontiers in Cardiovascular Medicine 6.
- Velasco, A.D.R.; Welten, S.M.J.; Goossens, E.A.C.; Quax, P.H.A.; Rappsilber, J.; Michlewski, G. & Nossent, A.Y. (2019), Posttranscriptional Regulation of 14q32 MicroRNAs by the CIRBP and HADHB during Vascular Regeneration after Ischemia, Molecular Therapy - Nucleic Acids 14: 329-338.
- Simons, K.H.; Jong, A. de; Jukema, J.W.; Vries, M.R. de; Arens, R. & Quax, P.H.A. (2019), T cell co-stimulation and co-inhibition in cardiovascular disease: a double-edged sword, Nature Reviews Cardiology 16(6): 325-343.
- Aref, Z.; Vries, M.R. de & Quax, P.H.A. (2019), Variations in Surgical Procedures for Inducing Hind Limb Ischemia in Mice and the Impact of These Variations on Neovascularization Assessment.
- Hoving, L.R.; Vries, M.R. de; Jong, R.C.M. de; Katiraei, S.; Pronk, A.; Quax, P.H.A.; Harmelen, V. van & Dijk, K.W. van (2018), The Prebiotic Inulin Aggravates Accelerated Atherosclerosis in Hypercholesterolemic APOE*3-Leiden Mice, Nutrients 10(2).
- Baganha, F.; Vries, M. de; Knutt, P. & Quax, P.H.A. (2018), A monoclonal human IgG1 phosphorylcholine antibody reduces vein graft remodelling, angiogenesis and intraplaque haemorrhage, Cardiovascular Research 114: S91-S91.
- Jong, R.C.M. de; Pluijmert, N.J.; Vries, M.R. de; Pettersson, K.; Atsma, D.E.; Jukema, J.W. & Quax, P.H.A. (2018), Annexin A5 reduces infarct size and improves cardiac function after myocardial ischemia-reperfusion injury by suppression of the cardiac inflammatory response, Scientific Reports 8.
- Van Der Kwast R. V. C. T., Van Ingen E., Parma L., Peters H. A. B., Quax P. H. A. & Nossent A. Y. N. (2018), A-to-I editing of microRNA-487b alters target gene selection and promotes neovascularization after ischemia, Cardiovascular Research 114: S6-S6.
- Hakansson, K.E.J.; Sollie, O.; Simons, K.H.; Quax, P.H.A.; Jensen, J. & Nossent, A.Y. (2018), Circulating Small Non-coding RNAs as Biomarkers for Recovery After Exhaustive or Repetitive Exercise, Frontiers in Physiology 9.
- Nowak-Sliwinska, P.; Alitalo, K.; Allen, E.; Anisimov, A.; Aplin, A.C.; Auerbach, R.; Augustin, H.G.; Bates, D.O.; Beijnum, J.R. van; Bender, R.H.F.; Bergers, G.; Bikfalvi, A.; Bischoff, J.; Bock, B.C.; Brooks, P.C.; Bussolino, F.; Cakir, B.; Carmeliet, P.; Castranova, D.; Cimpean, A.M.; Cleaver, O.; Coukos, G.; Davis, G.E.; Palma, M. de; Dimberg, A.; Dings, R.P.M.; Djonov, V.; Dudley, A.C.; Dufton, N.P.; Fendt, S.M.; Ferrara, N.; Fruttiger, M.; Fukumura, D.; Ghesquiere, B.; Gong, Y.; Griffin, R.J.; Harris, A.L.; Hughes, C.C.W.; Hultgren, N.W.; Iruela-Arispe, M.L.; Irving, M.; Jain, R.K.; Kalluri, R.; Kalucka, J.; Kerbel, R.S.; Kitajewski, J.; Klaassen, I.; Kleinmann, H.K.; Koolwijk, P.; Kuczynski, E.; Kwak, B.R.; Marien, K.; Melero-Martin, J.M.; Munn, L.L.; Nicosia, R.F.; Noel, A.; Nurro, J.; Olsson, A.K.; Petrova, T.V.; Pietras, K.; Pili, R.; Pollard, J.W.; Post, M.J.; Quax, P.H.A.; Rabinovich, G.A.; Raica, M.; Randi, A.M.; Ribatti, D.; Ruegg, C.; Schlingemann, R.O.; Schulte-Merker, S.; Smith, L.E.H.; Song, J.W.; Stacker, S.A.; Stalin, J.; Stratman, A.N.; Velde, M. van de; Hinsbergh, V.W.M. van; Vermeulen, P.B.; Waltenberger, J.; Weinstein, B.M.; Xin, H.; Yetkin-Arik, B.; Yla-Herttuala, S.; Yoder, M.C. & Griffioen, A.W. (2018), Consensus guidelines for the use and interpretation of angiogenesis assays, Angiogenesis 21(3): 425-532.
- Simons K. H., Peters H. A. B., Arens R., Jukema J. W., De Vries M. R. & Quax P. H. A. (2018), Co-stimulation dependent CD8 T cell activation protects vein graft disease, Cardiovascular Research 114: S50-S50.
- Smolders V., Blanco I., Piccari L., Garcia Lucio J., Zodda E., Sebastian L., Castella M., Osorio J., Cascante M., Peinado V. I., Quax P., Barbera J. A. & Tura-Ceide O. (2018), Dysfunctional Endothelial Cells in Patients with Chronic Thromboembolic Pulmonary Hypertension, American Journal of Respiratory and Critical Care Medicine 197.
- Van Ingen E., Foks A. C., Kroner M. J., Agrawal S., Kuiper J., Quax P. H. A., Bot I. & Nossent A. Y. (2018), Inhibition of microRNA-494 halts atherosclerotic plaque progression and stabilizes advanced atherosclerotic lesions, Cardiovascular Research 114: S57-S57.
- Nossent Y., van Ingen E., Foks A., Kroner M., Kuiper J., Quax P. & Bot I. (2018), Inhibition of microRNA-494 halts atherosclerotic plaque progression and stabilizes advanced atherosclerotic lesions, Wiener Klinische Wochenschrift 130: 88-89.
- Amersfoort, J.; Schaftenaar, F.H.; Douna, H.; Santbrink, P.J. van; Kroner, M.J.; Puijvelde, G.H.M. van; Quax, P.H.A.; Kuiper, J. & Bot, I. (2018), Lipocalin-2 contributes to experimental atherosclerosis in a stage-dependent manner, Atherosclerosis 275: 214-224.
- Simons, K.H.; Vries, M.R. de; Peters, H.A.B.; Hamming, J.F.; Jukema, J.W. & Quax, P.H.A. (2018), The protective role of Toll-like receptor 3 and type-I interferons in the pathophysiology of vein graft disease, Journal of Molecular and Cellular Cardiology 121: 16-24.
- Brinks, J.; Dijk, E.H.C. van; Habeeb, M.; Nikolaou, A.; Tsonaka, R.; Peters, H.A.B.; Sips, H.C.M.; Merbel, A.F. van de; Jong, E.K. de; Notenboom, R.G.E.; Kielbasa, S.M.; Maarel, S.M. van der; Quax, P.H.A.; Meijer, O.C. & Boon, C.J.F. (2018), The Effect of Corticosteroids on Human Choroidal Endothelial Cells: A Model to Study Central Serous Chorioretinopathy, Investigative Ophthalmology & Visual Science 59(13): 5682-5692.
- Dijk, E.H.C. van; Habeeb, M.; Nikolaou, A.; Brinks, J.; Tsonaka, S.; Peters, H.A.B.; Sips, H.C.M.; Merbel, A.F. van de; Jong, E. de; Notenboom, R.G.E.; Kielbasa, S.M.; Maarel, S.M. van der; Quax, P.H.A.; Meijer, O.C. & Boon, C.J.F. (2018), The effect of corticosteroids on human choroidal endothelial cells: a model to study central serous chorioretinopathy, Acta Ophthalmologica 96: 30-30.
- Adam, M.; Kooreman, N.G.; Jagger, A.; Wagenhauser, M.U.; Mehrkens, D.; Wang, Y.M.; Kayama, Y.; Toyama, K.; Raaz, U.; Schellinger, I.N.; Maegdefessel, L.; Spin, J.M.; Hamming, J.F.; Quax, P.H.A.; Baldus, S.; Wu, J.C. & Tsao, P.S. (2018), Systemic Upregulation of IL-10 (Interleukin-10) Using a Nonimmunogenic Vector Reduces Growth and Rate of Dissecting Abdominal Aortic Aneurysm, Arteriosclerosis, Thrombosis, and Vascular Biology 38(8): 1796-1805.
- Bezhaeva, T.; Vries, M.R. de; Geelhoed, W.J.; Veer, E.P. van der; Versteeg, S.; Alem, C.M.A. van; Voorzaat, B.M.; Eijkelkamp, N.; Bogt, K.E. van der; Agoulnik, A.I.; Zonneveld, A.J. van; Quax, P.H.A. & Rotmans, J.I. (2018), Relaxin receptor deficiency promotes vascular inflammation and impairs outward remodeling in arteriovenous fistulas, FASEB Journal 32(11): 6293-6304.
- Pluijmert, N.J.; Jong, R.C.M. de; Vries, M.R. de; Pettersson, K.; Jukema, J.W. & Quax, P.H.A. (2018), Phosphorylcholine antibodies preserve cardiac function and reduce infarct size by attenuation of the inflammatory response following myocardial ischemia-reperfusion injury, Cardiovascular Research 114: S125-S126.
- Nossent, A.Y.; Hakansson, K.J.E.; Goossens, E.A.C.; Trompet, S.; Kwast, R.V.T.C. van der; Vries, M.R. de; Ripa, R.; Kastrup, J.; Jukema, J.W. & Quax, P.H.A. (2018), More on noncoding RNAs: genetic associations, regulation of expression and in vitro studies show an independent role for small nucleolar RNAs in cardiovascular disease, Cardiovascular Research 114: S40-S40.
- Goossens E. A. C., Quax P. H. A. & Nossent A. Y. (2018), MiR-map: a comprehensive atlas of vascular microRNA expression shows vessel-specific expression profiles of the vasoactive 14q32 microRNAs, Cardiovascular Research 114: S64-S64.
- Kooreman, N.G.; Kim, Y.; Almeida, P.E. de; Termglinchan, V.; Diecke, S.; Shao, N.Y.; Wei, T.T.; Yi, H.; Dey, D.; Nelakanti, R.; Brouwer, T.P.; Paik, D.T.; Sagiv-Barfi, I.; Han, A.; Quax, P.H.A.; Hamming, J.F.; Levy, R.; Davis, M.M. & Wu, J.C. (2018), Autologous iPSC-Based Vaccines Elicit Anti-tumor Responses In Vivo, Cell Stem Cell 22(4): 501-+.
- Vries, M.R. de & Quax, P.H.A. (2018), Inflammation in Vein Graft Disease, Frontiers in Cardiovascular Medicine 5.
- Brinks, J.; Dijk, E.H.C. van; Habeeb, M.; Nikolaou, A.; Tsonaka, R.; Peters, H.A.B.; Sips, H.C.M.; Merbel, A.F. van de; Jong, E.K. de; Notenboom, R.G.E.; Kielbasa, S.M.; Maarel, S.M. van der; Quax, P.H.A.; Meijer, O.C. & Boon, C.J.F. (2018), The effect of corticosteroids on human choroidal endothelial cells: a model to study central serous chorioretinopathy, Investigative Ophthalmology & Visual Science 59(13): 5682-5692.
- Simons, K.H.; Aref, Z.; Peters, H.A.B.; Welten, S.P.; Nossent, A.Y.; Jukema, J.W.; Hamming, J.F.; Arens, R.; Vries, M.R. de & Quax, P.H.A. (2018), The role of CD27-CD70-mediated T cell co-stimulation in vasculogenesis, arteriogenesis and angiogenesis, International Journal of Cardiology 260: 184-190.
- Jong, R.C.M. de; Pluijmert, N.J.; Vries, M.R. de; Pettersson, K.; Atsma, D.E.; Jukema, J.W. & Quax, P.H.A. (2018), Annexin A5 reduces infarct size and improves cardiac function after myocardial ischemia-reperfusion injury by suppression of the cardiac inflammatory response., Scientific Reports 8(1).
- Van Dijk Elon H., Habeeb Mahmoud, Nikolaou Aikaterini, Brinks Joost, Tsonaka Roula, Peters Hendrika, Sips Hetty, van de Merbel Arjanneke, de Jong Eiko, Notenboom Robbert, Kielbasa Szymon, van der Maarel Silvere, Quax Paul, Meijer Onno & Boon Camiel (2018), The effect of corticosteroids on human choroidal endothelial cells: a model to study central serous chorioretinopathy, Investigative Ophthalmology & Visual Science 59(9).
- Kwast, R.V.C.T. van der; Ingen, E. van; Parma, L.; Peters, H.A.B.; Quax, P.H.A. & Nossent, A.Y. (2018), Adenosine-to-Inosine Editing of MicroRNA-487b Alters Target Gene Selection After Ischemia and Promotes Neovascularization, Circulation Research 122(3): 444-456.
- Kupreishvili, K.; Meischl, C.; Vonk, A.B.A.; Stooker, W.; Eijsman, L.; Blom, A.M.; Quax, P.H.A.; Hinsbergh, V.W.M. van; Niessen, H.W.M. & Krijnen, P.A.J. (2017), Arterial Blood Pressure Induces Transient C4b-Binding Protein in Human Saphenous Vein Grafts, Annals of Vascular Surgery 41: 259-264.
- Nossent, A.Y.; Bastiaansen, A.J.N.M.; Peters, E.A.B.; Vries, M.R. de; Aref, Z.; Welten, S.M.J.; Jager, S.C.A. de; Kraan, T.C.T.M.V. & Quax, P.H.A. (2017), CCR7-CCL19/CCL21 Axis is Essential for Effective Arteriogenesis in a Murine Model of Hindlimb Ischemia, Journal of the American Heart Association 6(3).
- Vazao, H.; Rosa, S.; Barata, T.; Costa, R.; Pitrez, P.R.; Honorio, I.; Vries, M.R. de; Papatsenko, D.; Benedito, R.; Saris, D.; Khademhosseini, A.; Quax, P.H.A.; Pereira, C.F.; Mercader, N.; Fernandes, H. & Ferreira, L. (2017), High-throughput identification of small molecules that affect human embryonic vascular development, Proceedings of the National Academy of Sciences 114(15): E3022-E3031.
- Welten, S.M.J.; Jong, R.C.M. de; Wezel, A.; Vries, M.R. de; Boonstra, M.C.; Parma, L.; Jukema, J.W.; Sluis, T.C. van der; Arens, R.; Bot, I.; Agrawal, S.; Quax, P.H.A. & Nossent, A.Y. (2017), Inhibition of 14q32 microRNA miR-495 reduces lesion formation, intimal hyperplasia and plasma cholesterol levels in experimental restenosis, Atherosclerosis 261: 26-36.
- Kooreman, N.G.; Almeida, P.E. de; Stack, J.P.; Nelakanti, R.V.; Diecke, S.; Shao, N.Y.; Swijnenburg, R.J.; Sanchez-Freire, V.; Matsa, E.; Liu, C.; Connolly, A.J.; Hamming, J.F.; Quax, P.H.A.; Brehm, M.A.; Greiner, D.L.; Shultz, L.D. & Wu, J.C. (2017), Alloimmune Responses of Humanized Mice to Human Pluripotent Stem Cell Therapeutics, Cell Reports 20(8): 1978-1990.
- Simons, K.H.; Peters, H.A.B.; Jukema, J.W.; Vries, M.R. de & Quax, P.H.A. (2017), A protective role of IRF3 and IRF7 signalling downstream TLRs in the development of vein graft disease via type I interferons, Journal of Internal Medicine 282(6): 522-536.
- Bezhaeva, T.; Wong, C.; Vries, M.R. de; Veer, E.P. van der; Alem, C.M.A. van; Que, I.; Lalai, R.A.; Zonneveld, A.J. van; Rotmans, J.I. & Quax, P.H.A. (2017), Deficiency of TLR4 homologue RP105 aggravates outward remodeling in a murine model of arteriovenous fistula failure, Scientific Reports 7.
- Welten, S.M.J.; Vries, M.R. de; Peters, E.A.B.; Agrawal, S.; Quax, P.H.A. & Nossent, A.Y. (2017), Inhibition of Mef2a Enhances Neovascularization via Post-transcriptional Regulation of 14q32 MicroRNAs miR-329 and miR-494, Molecular Therapy - Nucleic Acids 7: 61-70.
- Parma, L.; Baganha, F.; Quax, P.H.A. & Vries, M.R. de (2017), Plaque angiogenesis and intraplaque hemorrhage in atherosclerosis, European Journal of Pharmacology 816: 107-115.
- Kupreishvili, K.; Stooker, W.; Emmens, R.W.; Vonk, A.B.A.; Sipkens, J.A.; Dijk, A. van; Eijsman, L.; Quax, P.H.; Hinsbergh, V.W.M. van; Krijnen, P.A.J. & Niessen, H.W.M. (2017), PX-18 Protects Human Saphenous Vein Endothelial Cells under Arterial Blood Pressure, Annals of Vascular Surgery 42: 293-298.
- Jong, R.C.M. de; Ewing, M.M.; Vries, M.R. de; Karper, J.C.; Bastiaansen, A.J.N.M.; Peters, H.A.B.; Baghana, F.; Elsen, P.J. van den; Gongora, C.; Jukema, J.W. & Quax, P.H.A. (2017), The epigenetic factor PCAF regulates vascular inflammation and is essential for intimal hyperplasia development, PLoS ONE 12(10).
- Vries, M.R. de; Peters, E.A.B.; Quax, P.H.A. & Nossent, A.Y. (2017), von Willebrand factor deficiency leads to impaired blood flow recovery after ischaemia in mice, Thrombosis and Haemostasis 117(7): 1412-1419.
- Wezel A., Vries M.R. de, Maassen J.M., Kip P., Peters E.A., Karper J.C., Kuiper J., Bot I. & Quax P.H.A. (2016), Deficiency of the TLR4 analogue RP105 aggravates vein graft disease by inducing a pro-inflammatory response, Scientific Reports 6: 24248.
- Frodermann V., Duijn J. van, Puijvelde G.H.M. van, Santbrink P.J. van, Lagraauw H.M., Vries M.R. de, Quax P.H.A., Bot I., Foks A.C., Jager S.C. de & Kuiper J. (2016), Heat-killed Staphylococcus aureus reduces atherosclerosis by inducing anti-inflammatory macrophages, Journal of Internal Medicine 279(6): 592-605.
- Trompet, S.; Vries, M. de; Welten, S.; Kwast, R. van der; Jukema, W.; Agrawal, S.; Quax, P. & Nossent, A.Y. (2016), C/D Box Small Nucleolar RNAs of the 14q32 Noncoding RNA Gene Cluster Play an Important Role in Human Cardiovascular Disease, Circulation 134.
- Bezhaeva, T.; Wong, C.Y.; Vries, M.R. de; Veer, E.P. van der; Alem, C.M.A. van; Rotmans, J.I. & Quax, P.H.A. (2016), Deficiency of Tlr4 Homologue Rp105 Aggravates Outward Remodelling in a Murine Model of Arteriovenous Fistula Failure, Circulation 134.
- Welten, S.; Vries, M. de; Peters, E.; Agrawal, S.; Quax, P. & Nossent, A.Y. (2016), Inhibition of MEF2A Using 3rd Generation Antisense Enhances Neovascularization via Posttranscriptional Regulation of 14q32 MicroRNAs miR-329 and miR-494, Circulation 134.
- Simons, K.H.; Vries, M.R. de; Peters, E.A.; Hamming, J.F.; Jukema, J.W. & Quax, P.H. (2016), Interferon Regulatory Factors 3 and 7 Regulate Vein Graft Remodeling via Tumor Necrosis Factor Induced Macrophage Accumulation, Circulation 134.
- Kwast, R. van der; Quax, P. & Nossent, A.Y. (2016), The Vasoactive MicroRNA miR-487b-3p Undergoes A-to-I Editing of the Seed-Sequence During Post-Ischemic Neovascularization, Circulation 134.
- Nieuwland, A.J.; Kokje, V.B.C.; Koning, O.H.; Hamming, J.F.; Szuhai, K.; Claas, F.H.J. & Lindeman, J.H.N. (2016), Activation of the vitamin D receptor selectively interferes with calcineurin-mediated inflammation: a clinical evaluation in the abdominal aortic aneurysm, Laboratory Investigation 96(7): 784-790.
- Van Dijk R. A., Rijs K., Wezel A., Hamming J. F., Kolodgie F. D., Virmani R., Schaapherder A. F. & Lindeman J. H. N. (2016), A systematic evaluation of the cellular innate immune response during the process of human atherosclerosis, Cardiovascular Research 111: S29-S29.
- Dongen, T.T.C.F. van; Idenburg, F.J.; Tan, E.C.T.H.; Rasmussen, T.E.; Hamming, J.F.; Leenen, L.P.H. & Hoencamp, R. (2016), Combat related vascular injuries: Dutch experiences from a role 2 MTF in Afghanistan, Injury 47(1): 94-98.
- Rothuizen, T.C.; Damanik, F.F.R.; Lavrijsen, T.; Visser, M.J.T.; Hamming, J.F.; Lalai, R.A.; Duijs, J.M.G.J.; Zonneveld, A.J. van; Hoefer, I.E.; Blitterswijk, C.A. van; Rabelink, T.J.; Moroni, L. & Rotmans, J.I. (2016), Development and evaluation of in vivo tissue engineered blood vessels in a porcine model, Biomaterials 75: 82-90.
- Meershoek, A.; Dijk, R.A. van; Verhage, S.; Hamming, J.F.; Bogaerdt, A.J. van den; Bogers, A.J.J.C.; Schaapherder, A.F. & Lindeman, J.H. (2016), Histological evaluation disqualifies IMT and calcification scores as surrogates for grading coronary and aortic atherosclerosis, International Journal of Cardiology 224: 328-334.
- Dijk, R.A. van; Rijs, K.; Wezel, A.; Hamming, J.F.; Kolodgie, F.D.; Virmani, R.; Schaapherder, A.F. & Lindeman, J.H.N. (2016), Systematic Evaluation of the Cellular Innate Immune Response During the Process of Human Atherosclerosis, Journal of the American Heart Association 5(6).
- Spruit, E.N.; Kleijweg, L.; Band, G.P.H. & Hamming, J.F. (2016), Varied Practice in Laparoscopy Training: Beneficial Learning Stimulation or Cognitive Overload?, Frontiers in Psychology 7.
- Wong, C.Y.; Vries, M.R. de; Wang, Y.; Vorst, J.R. van der; Vahrmeijer, A.L.; Zonneveld, A.J. van; Hamming, J.F.; Roy-Chaudhury, P.; Rabelink, T.J.; Quax, P.H.A. & Rotmans, J.I. (2016), A Novel Murine Model of Arteriovenous Fistula Failure: The Surgical Procedure in Detail, Journal of Visualized Experiments.
- Caolo, V.; Vries, M.; Zupancich, J.; Houben, M.; Mihov, G.; Wagenaar, A.; Swennen, G.; Nossent, Y.; Quax, P.; Suylen, D.; Dijkgraaf, I.; Molin, D.; Hackeng, T. & Post, M. (2016), CXCL1 microspheres: a novel tool to stimulate arteriogenesis, Drug Delivery 23(8): 2919-2926.
- Wezel, A.; Vries, M.R. de; Maassen, J.M.; Kip, P.; Peters, E.A.; Karper, J.C.; Kuiper, J.; Bot, I. & Quax, P.H.A. (2016), Deficiency of the TLR4 analogue RP105 aggravates vein graft disease by inducing a pro-inflammatory response, Scientific Reports 6.
- Frodermann, V.; Duijn, J. van; Puijvelde, G.H.M. van; Santbrink, P.J. van; Lagraauw, H.M.; Vries, M.R. de; Quax, P.H.A.; Bot, I.; Foks, A.C.; Jager, S.C.A. de & Kuiper, J. (2016), Heat-killed Staphylococcus aureus reduces atherosclerosis by inducing anti-inflammatory macrophages, Journal of Internal Medicine 279(6): 592-605.
- Kokje, V.B.C.; Gabel, G.; Koole, D.; Northoff, B.H.; Holdt, L.M.; Hamming, J.F. & Lindeman, J.H.N. (2016), IL-6: A Janus-like factor in abdominal aortic aneurysm disease, Atherosclerosis 251: 139-146.
- Wong, C.Y.; Bezhaeva, T.; Rothuizen, T.C.; Metselaar, J.M.; Vries, M.R. de; Verbeek, F.P.R.; Vahrmeijer, A.L.; Wezel, A.; Zonneveld, A.J. van; Rabelink, T.J.; Quax, P.H.A. & Rotmans, J.I. (2016), Liposomal prednisolone inhibits vascular inflammation and enhances venous outward remodeling in a murine arteriovenous fistula model, Scientific Reports 6.
- Vries, M.R. de & Quax, P.H.A. (2016), Plaque angiogenesis and its relation to inflammation and atherosclerotic plaque destabilization, Current Opinion in Lipidology 27(5): 499-506.
- Vries, M.R. de; Peters, H.A.B.; Hamming, J.F.; Goumans, M.J. & Quax, P.H.A. (2016), PLAQUE NEOVESSEL MATURATION ENHANCEMENT BY VEGFR2 BLOCKADE REDUCES INTRAPLAQUE HAEMORRHAGE, Atherosclerosis 244: E6-E6.
- Welten, S.M.J.; Goossens, E.A.C.; Quax, P.H.A. & Nossent, A.Y. (2016), The multifactorial nature of microRNAs in vascular remodelling, Cardiovascular Research 110(1): 6-22.
- Vries, M.R. de; Simons, K.H.; Jukema, J.W.; Braun, J. & Quax, P.H.A. (2016), Vein graft failure: from pathophysiology to clinical outcomes, Nature Reviews Cardiology 13(8): 451-470.
- Wezel A., Lagraauw H.M., Velden D. van der, Jager S.C. de, Quax P.H.A., Kuiper J. & Bot I. (2015), Mast cells mediate neutrophil recruitment during atherosclerotic plaque progression, Atherosclerosis 241(2): 289-296.
- Wezel A., Welten S.M., Razawy W., Lagraauw H.M., Vries M.R. de, Goossens E.A., Boonstra M.C., Hamming J.F., Kandimalla E.R, Kuiper J., Quax P.H.A, Nossent A.Y. & Bot I. (2015), Inhibition of MicroRNA-494 Reduces Carotid Artery Atherosclerotic Lesion Development and Increases Plaque Stability, Annals of Surgery 262(5): 841-848.
- Vries, M.R. de; Peters, E.A.; Hamming, J.F.; Goumans, M.T. & Quax, P.H. (2015), VEGFR2 Blockade in Murine Vein Grafts Reduces Intraplaque Hemorrhage due to Enhanced Plaque Neovessel Maturation, Circulation 132.
- Wong, C.Y.; Rothuizen, T.C.; Vries, M.R. de; Rabelink, T.J.; Hamming, J.F.; Zonneveld, A.J. van; Quax, P.H.A. & Rotmans, J.I. (2015), Elastin is a Key Regulator of Outward Remodeling in Arteriovenous Fistulas, European Journal of Vascular and Endovascular Surgery 49(4): 480-486.
- Hakimzadeh, N.; Nossent, A.Y.; Laan, A. van der; Schirmer, S.; Royen, N. van; Quax, P.; Hoefer, I. & Piek, J. (2015), Circulating MicroRNAs Characterize Insufficient Coronary Collateral Artery Development in Patients with Chronic Total Occlusion, FASEB Journal 29.
- Wezel, A.; Quax, P.H.A.; Kuiper, J. & Bot, I. (2015), The role of mast cells in atherosclerosis, H�mostaseologie 35(2): 113-120.
- Vries, M. de; Wezel, A.; Maassen, J.; Kip, P.; Peters, H.; Karper, J.; Kuiper, J.; Bot, I. & Quax, P. (2015), RP105 DEFICIENCY AGGRAVATES VEIN GRAFT DISEASE AND LESION INSTABILITY VIA INCREASED INFLAMMATION AND MAST CELL ACTIVATION, Atherosclerosis 241(1): E29-E29.
- Jukema, J.W.; Brouwer, J.R.; Luscher, T.F.; Engberts, D.P. & Quax, P.H.A. (2015), Research ethics needs fine tuning, not rigidity: how to promote evidence in neglected patient populations by rethinking informed consent, European Heart Journal 36(40): 2681-2685.
- Welten, S.M.J.; Quax, P.H.A. & Nossent, A.Y. (2015), MicroRNA-155 Exerts Cell-Specific Antiangiogenic but Proarteriogenic Effects During Adaptive Neovascularization, Circulation 132(23): e375-e375.
- Wezel, A.; Lagraauw, H.M.; Velden, D. van der; Jager, S.C.A. de; Quax, P.H.A.; Kuiper, J. & Bot, I. (2015), Mast cells mediate neutrophil recruitment during atherosclerotic plaque progression, Atherosclerosis 241(2): 289-296.
- Wezel, A.; Welten, S.M.J.; Razawy, W.; Lagraauw, H.M.; Vries, M.R. de; Goossens, E.A.C.; Boonstra, M.C.; Hamming, J.F.; Kandimalla, E.R.; Kuiper, J.; Quax, P.H.A.; Nossent, A.Y. & Bot, I. (2015), Inhibition of MicroRNA-494 Reduces Carotid Artery Atherosclerotic Lesion Development and Increases Plaque Stability, Annals of Surgery 262(5): 841-848.
- Yildirim, C.; Vogel, D.Y.S.; Hollander, M.R.; Baggen, J.M.; Fontijn, R.D.; Nieuwenhuis, S.; Haverkamp, A.; Vries, M.R. de; Quax, P.H.A.; Garcia-Vallejo, J.J.; Laan, A.M. van der; Dijkstra, C.D.; Kraan, T.C.T.M.V.; Royen, N. van & Horrevoets, A.J.G. (2015), Galectin-2 Induces a Proinflammatory, Anti-Arteriogenic Phenotype in Monocytes and Macrophages.
- Gielen, C.L.I.; Grimbergen, J.; Klautz, R.J.M.; Koopman, J. & Quax, P.H.A. (2015), Fibrinogen reduction and coagulation in cardiac surgery: an investigational study, Blood Coagulation and Fibrinolysis 26(6): 613-620.
- Hakimzadeh, N.; Nossent, A.Y.; Laan, A.M. van der; Schirmer, S.H.; Ronde, M.W.J. de; Pinto-Sietsma, S.J.; Royen, N. van; Quax, P.H.A.; Hoefer, I.E. & Piek, J.J. (2015), Circulating MicroRNAs Characterizing Patients with Insufficient Coronary Collateral Artery Function.
- Wezel, A.; Velden, D. van der; Maassen, J.M.; Lagraauw, H.M.; Vries, M.R. de; Karper, J.C.; Kuiper, J.; Bot, I. & Quax, P.H.A. (2015), RP105 deficiency attenuates early atherosclerosis via decreased monocyte influx in a CCR2 dependent manner, Atherosclerosis 238(1): 132-139.
- Wezel A., Vries M.R. de, Lagraauw H.M., Foks A.C., Kuiper J., Quax P.H.A. & Bot I. (2014), Complement factor C5a induces atherosclerotic plaque disruptions, Journal of Cellular and Molecular Medicine 18(10): 2020-2030.
- Willems S., Velden D. van der, Quax P.H., Borst G.J. de, Vries J.P. de, Moll F.L, Kuiper J., Toes R.E, Jager S.C. de, Kleijn D.P. de, Hoefer I.E., Pasterkamp G. & Bot I. (2014), Circulating immunoglobulins are not associated with intraplaque mast cell number and other vulnerable plaque characteristics in patients with carotid artery stenosis, PLoS ONE 9(2): e88984.
- Wezel, A.; Vries, M.R. de; Lagraauw, H.M.; Foks, A.C.; Kuiper, J.; Quax, P.H. & Bot, I. (2014), Complement factor C5a induces atherosclerotic plaque disruptions.
- Willems, S.; Velden, D. van der; Quax, P.H.A.; Borst, G.J. de; Vries, J.P.P.M. de; Moll, F.L.; Kuiper, J.; Toes, R.E.M.; Jager, S.C.A. de; Kleijn, D.P.V. de; Hoefer, I.E.; Pasterkamp, G. & Bot, I. (2014), Circulating Immunoglobulins Are Not Associated with Intraplaque Mast Cell Number and Other Vulnerable Plaque Characteristics in Patients with Carotid Artery Stenosis, PLoS ONE 9(2).
- Lijkwan, M.A.; Hellingman, A.A.; Bos, E.J.; Bogt, K.E.A. van der; Huang, M.; Kooreman, N.G.; Vries, M.R. de; Peters, H.A.B.; Robbins, R.C.; Hamming, J.F.; Quax, P.H.A. & Wu, J.C. (2014), Short Hairpin RNA Gene Silencing of Prolyl Hydroxylase-2 with a Minicircle Vector Improves Neovascularization of Hindlimb Ischemia, Human Gene Therapy 25(1): 41-49.
- de Jong R. C., Pluijmert N. J., Pettersson K., Schutte C., Atsma D. & Quax P. (2014), ANTI-PHOSPHORYLCHOLINE THERAPY RESTRICTS LEFT VENTRICULAR REMODELING AFTER MYOCARDIAL ISCHEMIA-REPERFUSION INJURY IN HYPERCHOLESTEROLEMIC APOE*3-LEIDEN MICE, Atherosclerosis 235(2): E77-E77.
- Bot, I.; Wezel, A.; Lagraauw, H.M.; Velden, D. van der; Jager, S.C.A. de; Quax, P.H.A. & Kuiper, J. (2014), Mast cell mediated neutrophil influx enhances plaque progression, Cardiovascular Research 103.
- Gremmels, H.; Teraa, M.; Quax, P.H.A.; Ouden, K. den; Fledderus, J. & Verhaar, M.C. (2014), Neovascularization Capacity of Mesenchymal Stromal Cells From Critical Limb Ischemia Patients Is Equivalent to Healthy Controls, Molecular Therapy 22(11): 1960-1970.
- Borne, P. van den; Rygiel, T.P.; Hoogendoorn, A.; Westerlaken, G.H.A.; Boon, L.; Quax, P.H.A.; Pasterkamp, G.; Hoefer, I.E. & Meyaard, L. (2014), The cd200-cd200 receptor axis controls arteriogenesis and local tissue t lymphocyte influx, European Heart Journal 35: 377-378.
- Borne, P. van den; Rygiel, T.P.; Hoogendoorn, A.; Westerlaken, G.H.A.; Boon, L.; Quax, P.H.A.; Pasterkamp, G.; Hoefer, I.E. & Meyaard, L. (2014), The CD200-CD200 Receptor Inhibitory Axis Controls Arteriogenesis and Local T Lymphocyte Influx, PLoS ONE 9(6).
- Borne, P. van den; Quax, P.H.A.; Hoefer, I.E. & Pasterkamp, G. (2014), The Multifaceted Functions of CXCL10 in Cardiovascular Disease, BioMed Research International.
- Bastiaansen, A.J.N.M.; Karper, J.C.; Wezel, A.; Boer, H.C. de; Welten, S.M.J.; Jong, R.C.M. de; Peters, E.A.B.; Vries, M.R. de; Oeveren-Rietdijk, A.M. van; Zonneveld, A.J. van; Hamming, J.F.; Nossent, A.Y. & Quax, P.H.A. (2014), TLR4 Accessory Molecule RP105 (CD180) Regulates Monocyte-Driven Arteriogenesis in a Murine Hind Limb Ischemia Model, PLoS ONE 9(6).
- Borne, P. van den; Bastiaansen, A.J.N.M.; Vries, M.R. de; Quax, P.H.A.; Hoefer, I.E. & Pasterkamp, G. (2014), Toll-like Receptor 4 Inhibitor TAK-242 Treatment Does Not Influence Perfusion Recovery in Tissue Ischemia, Journal of Cardiovascular Pharmacology 63(1): 16-22.
- Vries, M.R. de; Jong, R.C.M. de; Peters, H.A.B.; Hamming, J.F.; Goumans, M.J. & Quax, P.H.A. (2014), VEGFR2 blockade enhances plaque neovessel maturation and decreases intraplaque hemorrhage, Angiogenesis 17(3): 764-764.
- Vries, M.R. de; Jong, R.C.M. de; Peters, H.A.B.; Hamming, J.F.; Goumans, M.J. & Quax, P.H.A. (2014), VEGFR2 BLOCKADE IN MURINE VEIN GRAFT RESULTS IN REDUCED INTRAPLAQUE HEMORRHAGE AND STABLE ATHEROSCLEROTIC LESIONS, Atherosclerosis 235(2): E161-E162.
- Wong, C.Y.; Vries, M.R. de; Wang, Y.; Vorst, J.R. van der; Vahrmeijer, A.L.; Zonneveld, A.J. van; Roy-Chaudhury, P.; Rabelink, T.J.; Quax, P.H.A. & Rotmans, J.I. (2014), Vascular remodeling and intimal hyperplasia in a novel murine model of arteriovenous fistula failure, Journal of Vascular Surgery 59(1): 192-+.
- Borne, P. van den; Haverslag, R.T.; Brandt, M.M.; Cheng, C.; Duckers, H.J.; Quax, P.H.A.; Hoefer, I.E.; Pasterkamp, G. & Kleijn, D.P.V. de (2014), Absence of Chemokine (C-X-C Motif) Ligand 10 Diminishes Perfusion Recovery After Local Arterial Occlusion in Mice, Arteriosclerosis, Thrombosis, and Vascular Biology 34(3): 594-602.
- Wezel, A.; Welten, S.; Razawy, W.; Lagraauw, M.; Vries, M. de; Kandimalla, E.; Kuiper, J.; Quax, P.; Bot, I. & Nossent, Y. (2014), 14Q32 MICRORNA INHIBITION REDUCES ATHEROSCLEROTIC LESION FORMATION, INCREASES PLAQUE STABILITY AND LOWERS CHOLESTEROL LEVELS, Atherosclerosis 235(2): E41-E41.
- Bakker, W.; Dingenouts, C.K.E.; Lodder, K.; Vries, M.R. de; Mager, H.J.; Snijder, R.J.; Westerman, C.J.; Dijke, P.; Quax, P.H. & Goumans, M.J.T.H. (2014), Impaired macrophage polarization in endoglin haplo-insufficiency leading to defective tissue repair is recovered by counter balance the TGFbeta pathway, Cardiovascular Research 103.
- Louwe, M.C.; Karper, J.C.; Vries, M.R. de; Nossent, A.Y.; Bastiaansen, A.J.N.M.; Hoorn, J.W.A. van der; Dijk, K.W. van; Rensen, P.C.N.; Steendijk, P.; Smit, J.W.A. & Quax, P.H.A. (2014), RP105 deficiency aggravates cardiac dysfunction after myocardial infarction in mice, International Journal of Cardiology 176(3): 788-793.
- Louwe, M.C.; Karper, J.C.; Vries, M.R. de; Bastiaansen, A.J.N.M.; Hoorn, J.W.A. van der; Dijk, K.W. van; Rensen, P.C.N.; Steendijk, P.; Smit, J.W.A. & Quax, P.H.A. (2014), RP105 deficiency aggravates cardiac dysfunction after myocardial infarction in mice, Cardiovascular Research 103.
- Quax, P.H.A. (2014), Inflammation, the innate immune system and microRNAs modulating arteriogenesis, Angiogenesis 17(3): 718-719.
- Welten, S.M.J.; Bastiaansen, A.J.N.M.; Jong, R.C.M. de; Vries, M.R. de; Peters, E.A.B.; Boonstra, M.C.; Sheikh, S.P.; Monica, N. la; Kandimalla, E.R.; Quax, P.H.A. & Nossent, A.Y. (2014), Inhibition of 14q32 MicroRNAs miR-329, miR-487b, miR-494, and miR-495 Increases Neovascularization and Blood Flow Recovery After Ischemia, Circulation Research 115(8): 696-+.
- Welten, S.; Bastiaansen, T.; Jong, R. de; Vries, M. de; Peters, E.; Sheikh, S.; Monica, N. la; Kandimalla, E.; Quax, P. & Nossent, Y. (2014), Inhibition of Individual 14q32 microRNAs drastically increases neovascularization and blood flow recovery after ischemia, Angiogenesis 17(3): 761-761.
- Vries, M. de; Jong, R.C. de; Peters, E.H.; Hamming, J.F.; Goumans, M.J.; Bockel, H.J. van & Quax, P.H. (2014), Inhibition of VEGFR2 Reduces Angiogenic Microvessel Leakiness in Murine Vein Graft Atherosclerotic Lesions and Increased Plaque Stability, Journal of Vascular Surgery 59(6): 83S-84S.
- Yildirim, C.; Vogel, D.Y.S.; Hollander, M.R.; Baggen, J.M.; Fontijn, R.D.; Nieuwenhuis, S.; Haverkamp, A.; Vries, M.R. de; Garcia-Vallejo, J.J.; Ilarregui, J.M.; Laan, A.M. van der; Pouw-Kraan, T.C.T.M. van der; Quax, P.H.; Rabinovich, G.A.; Dijkstra, C.D.; Royen, N. van & Horrevoets, A.J.G. (2014), Galectin-2 skews monocyte/macrophages to a pro-inflammatory, anti-arteriogenic phenotype, Angiogenesis 17(3): 720-720.
- Borne, P. van den; Laan, S.W. van der; Bovens, S.M.; Koole, D.; Kowala, M.C.; Michael, L.F.; Schoneveld, A.H.; Weg, S.M. van de; Velema, E.; Vries, J.P. de; Borst, G.J. de; Moll, F.L.; Kleijn, D.P.V. de; Quax, P.H.A.; Hoefer, I.E. & Pasterkamp, G. (2014), Leukotriene B4 Levels in Human Atherosclerotic Plaques and Abdominal Aortic Aneurysms, PLoS ONE 9(1).
- Bot M., Jager S.C., MacAleese L., Lagraauw H.M., Berkel T.J.C. van, Quax P.H.A., Kuiper J., Heeren R.M., Biessen E.A. & Bot I. (2013), Lysophosphatidic acid triggers mast cell-driven atherosclerotic plaque destabilization by increasing vascular inflammation, Journal of Lipid Research 54(5): 1265-1274.
- Vries, M.R. de; Wezel, A.; Schepers, A.; Santbrink, P.J. van; Woodruff, T.M.; Niessen, H.W.M.; Hamming, J.F.; Kuiper, J.; Bot, I. & Quax, P.H.A. (2013), Complement factor C5a as mast cell activator mediates vascular remodelling in vein graft disease., Cardiovascular Research 97(2): 311-20.
- Veer, E.P. van der; Bruin, R.G. de; Kraaijeveld, A.O.; Vries, M.R. de; Bot, I.; Pera, T.; Segers, F.M.; Trompet, S.; Gils, J.M. van; Roeten, M.K.; Beckers, C.M.; Santbrink, P.J. van; Janssen, A.; Solingen, C. van; Swildens, J.; Boer, H.C. de; Peters, E.A.; Bijkerk, R.; Rousch, M.; Doop, M.; Kuiper, J.; Schalij, M.J.; Wal, A.C. van der; Richard, S.; Berkel, T.J.C. van; Pickering, J.G.; Hiemstra, P.S.; Goumans, M.J.; Rabelink, T.J.; Vries, A.A.F. de; Quax, P.H.A.; Jukema, J.W.; Biessen, E.A.L. & Zonneveld, A.J. van (2013), Quaking, an RNA-Binding Protein, Is a Critical Regulator of Vascular Smooth Muscle Cell Phenotype, Circulation Research 113(9): 1065-1075.
- Hengel, L.G. van den; Hellingman, A.A.; Nossent, A.Y.; Oeveren-Rietdijk, A.M. van; Vries, M.R. de; Spek, C.A.; Zonneveld, A.J. van; Reitsma, P.H.; Hamming, J.F.; Boer, H.C. de; Versteeg, H.H. & Quax, P.H.A. (2013), Protease-Activated Receptor (PAR)2, but Not PAR1, Is Involved in Collateral Formation and Anti-Inflammatory Monocyte Polarization in a Mouse Hind Limb Ischemia Model, PLoS ONE 8(4).
- Nossent, A.Y.; Welten, S.M.J.; Bastiaansen, A.J.N.M.; Jong, R.C.M. de; Vries, R.M. de; Peters, H.A.B. & Quax, P.H.A. (2013), Inhibition of 14q32 microRNAs drastically improves blood flow recovery after ischemia, European Heart Journal 34: 1053-1054.
- Eskildsen, T.V.; Jeppesen, P.L.; Schneider, M.; Nossent, A.Y.; Sandberg, M.B.; Hansen, P.B.L.; Jensen, C.H.; Hansen, M.L.; Marcussen, N.; Rasmussen, L.M.; Bie, P.; Andersen, D.C. & Sheikh, S.P. (2013), Angiotensin II Regulates microRNA-132/-212 in Hypertensive Rats and Humans, International Journal of Molecular Sciences 14(6): 11190-11207.
- Bastiaansen, A.J.N.M.; Ewing, M.M.; Boer, H.C.; Kraan, T.C.V.D.P.; Vries, M.R. de; Peters, E.A.B.; Welten, S.M.J.; Arens, R.; Moore, S.M.; Faber, J.E.; Jukema, J.W.; Hamming, J.F.; Nossent, A.Y. & Quax, P.H.A. (2013), Lysine Acetyltransferase PCAF Is a Key Regulator of Arteriogenesis, Arteriosclerosis, Thrombosis, and Vascular Biology 33(8): 1902-1910.
- Bot, M.; Jager, S.C.A. de; MacAleese, L.; Lagraauw, H.M.; Berkel, T.J.C. van; Quax, P.H.A.; Kuiper, J.; Heeren, R.M.A.; Biessen, E.A.L. & Bot, I. (2013), Lysophosphatidic acid triggers mast cell-driven atherosclerotic plaque destabilization by increasing vascular inflammation, Journal of Lipid Research 54(5): 1265-1274.
- Willems, S.; Vink, A.; Bot, I.; Quax, P.H.A.; Borst, G.J. de; Vries, J.P.P.M. de; Weg, S.M. van de; Moll, F.L.; Kuiper, J.; Kovanen, P.T.; Kleijn, D.P.V. de; Hoefer, I.E. & Pasterkamp, G. (2013), Mast cells in human carotid atherosclerotic plaques are associated with intraplaque microvessel density and the occurrence of future cardiovascular events, European Heart Journal 34(48): 3699-3706.
- Karper, J.C.; Ewing, M.M.; Vries, M.R. de; Jager, S.C.A. de; Peters, E.A.B.; Boer, H.C. de; Zonneveld, A.J. van; Kuiper, J.; Huizinga, E.G.; Brondijk, T.H.C.; Jukema, J.W. & Quax, P.H.A. (2013), TLR Accessory Molecule RP105 (CD180) Is Involved in Post-Interventional Vascular Remodeling and Soluble RP105 Modulates Neointima Formation, PLoS ONE 8(7).
- Bruin, R.G. de; Veer, E.P. van der; Vries, M. de; Gils, J. van; Kraaijeveld, A.; Rabelink, T.; Quax, P.H.; Jukema, W.; Biessen, E.A. & Zonneveld, A.J. van (2013), The RNA-Binding Protein Quaking Regulates Alternative Splicing Events in Myocardin That Determine Vascular Smooth Muscle Cell Phenotype, Circulation 128(22).
- Vries, M. de; Karper, J.C.; Kraan, T.C.V.; Peters, E.H.; Jong, R.C. de; Hamming, J.F.; Horrevoets, A.J. & Quax, P.H. (2013), The TLR3 Pathway Including Downstream Interferon Regulating Factors, Regulates Vein Graft Remodeling, Circulation 128(22).
- Ewing, M.M.; Karper, J.C.; Abdul, S.; Jong, R.C.M. de; Peters, H.A.B.; Vries, M.R. de; Redeker, A.; Kuiper, J.; Toes, R.E.M.; Arens, R.; Jukema, J.W. & Quax, P.H.A. (2013), T-cell co-stimulation by CD28-CD80/86 and its negative regulator CTLA-4 strongly influence accelerated atherosclerosis development, International Journal of Cardiology 168(3): 1965-1974.
- Ewing, M.M.; Karper, J.; Vries, M.R. de; Jong, R.C.M. de; Pettersson, K. & Quax, P. (2013), Optimized anti-phosphorylcholine IgG for therapeutic inhibition of inflammatory vascular disease, European Heart Journal 34: 1063-1063.
- Verschuren, J.J.W.; Trompet, S.; Sampietro, M.L.; Heijmans, B.T.; Koch, W.; Kastrati, A.; Houwing-Duistermaat, J.J.; Slagboom, P.E.; Quax, P.H.A. & Jukema, J.W. (2013), Pathway Analysis Using Genome-Wide Association Study Data for Coronary Restenosis - A Potential Role for the PARVB Gene, PLoS ONE 8(8).
- Nossent, A.Y.; Eskildsen, T.V.; Andersen, L.B.; Bie, P.; Bronnum, H.; Schneider, M.; Andersen, D.C.; Welten, S.M.J.; Jeppesen, P.L.; Hamming, J.F.; Hansen, J.L.; Quax, P.H. & Sheikh, S.P. (2013), The 14q32 MicroRNA-487b Targets the Antiapoptotic Insulin Receptor Substrate 1 in Hypertension-Induced Remodeling of the Aorta, Annals of Surgery 258(5): 743-753.
- Welten, S.; Bastiaansen, T.; Jong, R. de; Vries, M. de; Peters, E.; Sheikh, S.; Monica, N. la; Kandimalla, E.; Quax, P. & Nossent, Y. (2013), Inhibition of Individual 14q32 MicroRNAs Drastically Increases Neovascularization and Blood Flow Recovery After Ischemia, Circulation 128(22).
- Willems, S.; Quax, P.H.A.; Borst, G.J. de; Vries, J.P.P.M. de; Moll, F.L.; Kleijn, D.P.V. de; Hoefer, I.E. & Pasterkamp, G. (2013), Soluble ST2 levels are not associated with secondary cardiovascular events and vulnerable plaque phenotype in patients with carotid artery stenosis, Atherosclerosis 231(1): 48-53.
- Karper, J.; Jager, S.C.A. de; Ewing, M.M.; Vries, M.R. de; Arens, R.; Bot, I.; Jukema, J.W.; Kuiper, J. & Quax, P. (2013), RP105 (cd180) as a TLR-4 regulator ameliorates atherosclerosis via its role on B-cells, European Heart Journal 34: 441-441.
- Wezel, A.; Welten, S.; Razawy, W.; Lagraauw, M.; Vries, M. de; Kandimalla, E.; Kuiper, J.; Quax, P.; Bot, I. & Nossent, Y. (2013), 14q32 MicroRNA Inhibition Reduces Atherosclerotic Lesion Formation, Increases Plaque Stability and Lowers Cholesterol Levels, Circulation 128(22).
- Pluijmert N. J., Pettersson K., De Jong R. C. M., Schutte C. I., Atsma D. E. & Quax P. H. A. (2013), Anti-phosphorylcholine therapy restricts left ventricular remodeling after myocardial ischemia-reperfusion injury in hypercholesterolemic APOE(star)3-Leiden mice, European Heart Journal 34: 608-608.
- Karper, J.C.; Jager, S.C.A. de; Ewing, M.M.; Vries, M.R. de; Bot, I.; Santbrink, P.J. van; Redeker, A.; Mallat, Z.; Binder, C.J.; Arens, R.; Jukema, J.W.; Kuiper, J. & Quax, P.H.A. (2013), An Unexpected Intriguing Effect of Toll-Like Receptor Regulator RP105 (CD180) on Atherosclerosis Formation With Alterations on B-Cell Activation, Arteriosclerosis, Thrombosis, and Vascular Biology 33(12): 2810-2817.
- Rothuizen, T.C.; Wong, C.Y.; Quax, P.H.A.; Zonneveld, A.J. van; Rabelink, T.J. & Rotmans, J.I. (2013), Arteriovenous access failure: more than just intimal hyperplasia?, Nephrology Dialysis Transplantation 28(5): 1085-1092.
- Doorn, J.; Fernandes, H.A.M.; , B.Q. le; Peppel, J. van de; Leeuwen, J.P.T.M. van; Vries, M.R. de; Aref, Z.; Quax, P.H.A.; Myklebost, O.; Saris, D.B.F.; Blitterswijk, C.A. van & Boer, J. de (2013), A small molecule approach to engineering vascularized tissue, Biomaterials 34(12): 3053-3063.
- Vries, M.R. de; Seghers, L.; Bergen, J. van; Peters, H.A.B.; Jong, R.C.M. de; Hamming, J.F.; Toes, R.E.M.; Hinsbergh, V.W.M. van & Quax, P.H.A. (2013), C57BL/6 NK cell gene complex is crucially involved in vascular remodeling, Journal of Molecular and Cellular Cardiology 64: 51-58.
- Borne, P. van den; Haverslag, R.T.; Brandt, M.; Cheng, C.; Duckers, H.J.; Quax, P.H.A.; Hoefer, I.E.; Pasterkamp, G. & Kleijn, D.P.V. de (2013), Chemokine (c-x-c motif) ligand 10 deficiency causes impairment of perfusion recovery after local arterial occlusion, European Heart Journal 34: 807-807.
- Vries, M.R. de; Karper, J.C.; Peters, H.A.B.; Jong, R.C.M. de; Hamming, J.F. & Quax, P.H.A. (2013), Important protective effects of toll like receptor 3 and downstream interferon regulating factors on vein graft remodelling, European Heart Journal 34: 806-806.
- Vries M.R. de, Wezel A., Schepers A., Kuiper J., Bot I. & Quax P.H.A. (2012), Mast cell activation via complement factor C5a modulates vein graft remodeling and accelerated atherosclerosis, Vascular Pharmacology 56(5-6): 372-372.
- Karper J.C., Ewing M.M., Habets K.L., Vries M.R. de, Peters E.A., Oeveren-Rietdijk A.M. van, Boer H.C. de, Hamming J.F., Kuiper J., Kandimalla E.R., La Monica N., Jukema J.W. & Quax P.H. (2012), Blocking Toll-Like Receptors 7 and 9 Reduces Postinterventional Remodeling via reduced Macrophage Activation, Foam Cell Formation, and Migration, Arteriosclerosis and thrombosis: a journal of vascular biology/American Heart Associati 32(8): 72-80.
- Jager S.C. de, Karper J.C., Bot I., Vries M.R. de, Binder C.J., Kuiper J. & Quax P.H. (2012), Extracellular toll like receptor regulator RP105/CD180 ameliorates atherosclerosis via its role on B cells, Immunology 137: 296-296.
- Jager, S.C. de; Karper, J.C.; Bot, I.; Vries, M.R. de; Binder, C.J.; Kuiper, J. & Quax, P.H. (2012), Extracellular toll like receptor regulator RP105/CD180 ameliorates atherosclerosis via its role on B cells, Immunology 137: 296-296.
- Jukema, J.W.; Verschuren, J.J.W.; Ahmed, T.A.N. & Quax, P.H.A. (2012), Restenosis after PCI. Part 1: pathophysiology and risk factors, Nature Reviews Cardiology 9(1): 53-62.
- Vries, M.R. de; Niessen, H.W.M.; Lowik, C.W.G.M.; Hamming, J.F.; Jukema, J.W. & Quax, P.H.A. (2012), Plaque Rupture Complications in Murine Atherosclerotic Vein Grafts Can Be Prevented by TIMP-1 Overexpression, PLoS ONE 7(10): -.
- Laan, A.M. van der; Schirmer, S.H.; Vries, M.R. de; Koning, J.J.; Volger, O.L.; Fledderus, J.O.; Bastiaansen, A.J.N.M.; Hollander, M.R.; Baggen, J.M.; Koch, K.T.; Baan, J.; Henriques, J.P.; Schaaf, R.J. van der; Vis, M.M.; Mebius, R.E.; Kraan, T.C.V.; Quax, P.H.; Piek, J.J.; Horrevoets, A.J. & Royen, N. van (2012), Galectin-2 expression is dependent on the rs7291467 polymorphism and acts as an inhibitor of arteriogenesis, European Heart Journal 33(9): 1076-1084.
- Ewing, M.M.; Karper, J.C.; Sampietro, M.L.; Vries, M.R. de; Pettersson, K.; Jukema, J.W. & Quax, P.H.A. (2012), Annexin A5 prevents post-interventional accelerated atherosclerosis development in a dose-dependent fashion in mice.
- Roos, C.J.; Quax, P.H.A. & Jukema, J.W. (2012), Cardiovascular metabolic syndrome: mediators involved in the pathophysiology from obesity to coronary heart disease., Biomarkers in Medicine 6(1): 35-52.
- Karper, J.C.; Ewing, M.M.; Jukema, J.W. & Quax, P.H.A. (2012), Future potential biomarkers for postinterventional restenosis and accelerated atherosclerosis., Biomarkers in Medicine 6(1): 53-66.
- Vries, M.R. de; Wezel, A.; Schepers, A.; Kuiper, J.; Bot, I. & Quax, P.H.A. (2012), Mast cell activation via complement factor C5a modulates vein graft remodeling and accelerated atherosclerosis, Vascular Pharmacology 56(5-6): 372-372.
- Bogt, K.E.A. van der; Hellingman, A.A.; Lijkwan, M.A.; Bos, E.J.; Vries, M.R. de; Rappard, J.R.M. van; Fischbein, M.P.; Quax, P.H.; Robbins, R.C.; Hamming, J.F. & Wu, J.C. (2012), Molecular Imaging of Bone Marrow Mononuclear Cell Survival and Homing in Murine Peripheral Artery Disease, JACC: Cardiovascular Imaging 5(1): 46-55.
- Hellingman, A.A.; Vlugt, L.E.P.M. van der; Lijkwan, M.A.; Bastiaansen, A.J.N.M.; Sparwasser, T.; Smits, H.H.; Hamming, J.F. & Quax, P.H.A. (2012), A limited role for regulatory T cells in post-ischemic neovascularization, Journal of Cellular and Molecular Medicine 16(2): 328-336.
- Karper, J.C.; Ewing, M.M.; Habets, K.L.L.; Vries, M.R. de; Peters, E.A.B.; Oeveren-Rietdijk, A.M. van; Boer, H.C. de; Hamming, J.F.; Kuiper, J.; Kandimalla, E.R.; Monica, N. la; Jukema, J.W. & Quax, P.H.A. (2012), Blocking Toll-Like Receptors 7 and 9 Reduces Postinterventional Remodeling via Reduced Macrophage Activation, Foam Cell Formation, and Migration, Arteriosclerosis, Thrombosis, and Vascular Biology 32(8): E72-U88.
- Karper, J.C.; Ewing, M.M.; Habets, K.L.L.; Vries, M.R. de; Peters, E.A.B.; Oeveren-Rietdijk, A.M. van; Boer, H.C. de; Hamming, J.F.; Kuiper, J.; Kandimalla, E.R.; Monica, N. la; Jukema, J.W. & Quax, P.H.A. (2012), Blocking toll-like receptors 7 and 9 reduces postinterventional remodeling via reduced macrophage activation, foam cell formation, and migration.
- Vries, M.R. de; Niessen, H.W.M.; Lowik, L.; Jukema, J.W. & Quax, P.H.A. (2012), Spontaneous plaque disruptions, dissection, erosion and intraplaque hemorrhage in murine vein grafts can be attenuated by TIMP-1 overexpression, Vascular Pharmacology 56(5-6): 341-342.
- Bogt, K.E.A. van der; Hellingman, A.A.; Lijkwan, M.A.; Bos, E.J.; Vries, M.R. de; Rappard, J.R.M. van; Fischbein, M.P.; Quax, P.H.; Robbins, R.C.; Hamming, J.F. & Wu, J.C. (2012), Molecular imaging of bone marrow mononuclear cell survival and homing in murine peripheral artery disease.
- Vries, M.R. de; Niessen, H.W.M.; Lowik, C.W.G.M.; Hamming, J.F.; Jukema, J.W. & Quax, P.H.A. (2012), Plaque rupture complications in murine atherosclerotic vein grafts can be prevented by TIMP-1 overexpression., PLoS ONE 7(10): e47134.
- Bastiaansen, T.; Ewing, M.; Boer, H. de; Kraan, T.V.; Vries, M. de; Peters, E.; Arens, R.; Moore, S.; Faber, J.; Jukema, W.; Hamming, J.; Quax, P. & Nossent, A.Y. (2012), Differential Activation of HIF1-alpha is Associated with Reduced Arteriogenesis After Hind Limb Ischemia in PCAF-/- Mice, Circulation 126(21).
- Nossent, A.Y.; Bastiaansen, T.; Peters, E.; Jager, S. de; Kraan, T.V. & Quax, P. (2012), Chemokines CCL19 and CCL21 Contribute to Homing and Retention of T-Lymphocytes during Arteriogenesis via the Chemokine Receptor CCR7, Circulation 126(21).
- Seghers, L.; Vries, M.R. de; Pardali, E.; Hoefer, I.E.; Hierck, B.P.; Dijke, P. ten; Goumans, M.J. & Quax, P.H.A. (2012), Shear induced collateral artery growth modulated by endoglin but not by ALK1, Journal of Cellular and Molecular Medicine 16(10): 2440-2450.
- Bastiaansen, T.; Welten, S.; Kwast, R. van der; Jong, R. de; Vries, M. de; Peters, E.; Sheikh, S.; Monica, N. la; Quax, P. & Nossent, Y. (2012), Inhibition of 14q32 MicroRNAs Drastically Improves Blood Flow Recovery After Ischemia, Circulation 126(21).
- Krijnen, P.A.J.; Kupreishvili, K.; Vries, M.R. de; Schepers, A.; Stooker, W.; Vonk, A.B.A.; Eijsman, L.; Hinsbergh, V.W.M. van; Zeerleder, S.; Wouters, D.; Ham, M. van; Quax, P.H.A. & Niessen, H.W.M. (2012), C1-esterase inhibitor protects against early vein graft remodeling under arterial blood pressure, Atherosclerosis 220(1): 86-92.
- Vries M.R. de, Wezel A., Schepers A., Kuiper J., Bot I. & Quax P.H.A. (2011), Complement factor C5A modulates vein graft remodeling and accelerated atherosclerosis via interference in mast cell activation, Atherosclerosis Supplements 12(1): 79-79.
- Wezel A., De Vries M.R., Schepers A., Kuiper J., Bot I. & Quax P. (2011), Complement-factor C5a modulates vein graft remodeling and accelerated atherosclerosis via interference in Mast cell activation, Molecular Immunology 48(14): 1693-1693.
- Hellingman, A.A.; Zwaginga, J.J.; Beem, R.T. van; Hamming, J.F.; Fibbe, W.E.; Quax, P.H.A.; Geutskens, S.B. & TeRM Smart Mix Consortium (2011), T-cell-pre-stimulated Monocytes Promote Neovascularisation in a Murine Hind Limb Ischaemia Model., European Journal of Vascular and Endovascular Surgery 41(3): 418-28.
- Cynis, H.; Hoffmann, T.; Friedrich, D.; Kehlen, A.; Gans, K.; Kleinschmidt, M.; Rahfeld, J.U.; Wolf, R.; Wermann, M.; Stephan, A.; Haegele, M.; Sedlmeier, R.; Graubner, S.; Jagla, W.; Muller, A.; Eichentopf, R.; Heiser, U.; Seifert, F.; Quax, P.H.A.; Vries, M.R. de; Hesse, I.; Trautwein, D.; Wollert, U.; Berg, S.; Freyse, E.J.; Schilling, S. & Demuth, H.U. (2011), The isoenzyme of glutaminyl cyclase is an important regulator of monocyte infiltration under inflammatory conditions, EMBO Molecular Medicine 3(9): 545-558.
- Pettersson, K.; Ewing, M.M.; Vries, M.R. de; Atout, R.; Nordzell, M.; Sexton, D.J.; Charlotte, F.; Jukema, W.; Ninio, E.; Karabina, S. & Quax, P. (2011), A Fully Human Monoclonal IgG Phosphorylcholine Antibody Prevents Accelerated Atherosclerosis in Mice, Circulation 124(21): -.
- Hellingman, A.A.; Zwaginga, J.J.; Beem, R.T. van; Hamming, J.F.; Fibbe, W.E.; Quax, P.H.A.; Geutskens, S.B. & TeRM Smart Mix Consortium (2011), T-cell-pre-stimulated Monocytes Promote Neovascularisation in a Murine Hind Limb Ischaemia Model.
- Wezel, A.; Vries, M.R. de; Schepers, A.; Kuiper, J.; Bot, I. & Quax, P. (2011), Complement-factor C5a modulates vein graft remodeling and accelerated atherosclerosis via interference in Mast cell activation, Molecular Immunology 48(14): 1693-1693.
- Hellingman, A.A.; Vlugt, L.E.P.M. van der; Lijkwan, M.A.; Bastiaansen, A.J.N.M.; Sparwasser, T.; Smits, H.H.; Hamming, J.F. & Quax, P.H.A. (2011), A limited role for regulatory T cells in post-ischemic neovascularization.
- Jukema, J.W.; Verschuren, J.J.W.; Ahmed, T.A.N. & Quax, P.H.A. (2011), Restenosis after PCI. Part 1: pathophysiology and risk factors., Nature Reviews Cardiology 9(1): 53-62.
- Willems, S.; Vink, A.; Hoefer, I.; Quax, P. & Pasterkamp, G. (2011), HIGH MAST CELL NUMBERS IN HUMAN CAROTID ATHEROSCLEROTIC PLAQUES HAVE PREDICTIVE VALUE FOR FUTURE CARDIOVASCULAR EVENTS, Atherosclerosis. Supplements 12(1): 93-93.
- Solingen, C. van; Boer, H.C. de; Bijkerk, R.; Monge, M.; Oeveren-Rietdijk, A.M. van; Seghers, L.; Vries, M.R. de; Veer, E.P. van der; Quax, P.H.A.; Rabelink, T.J. & Zonneveld, A.J. van (2011), MicroRNA-126 modulates endothelial SDF-1 expression and mobilization of Sca-1(+)/Lin(-) progenitor cells in ischaemia., Cardiovascular Research 92(3): 449-55.
- Jukema, J.W.; Ahmed, T.A.N.; Verschuren, J.J.W. & Quax, P.H.A. (2011), Restenosis after PCI. Part 2: prevention and therapy., Nature Reviews Cardiology.
- Karper, J.C.; Vries, M.R. de; Brand, B.T. van den; Hoefer, I.E.; Fischer, J.W.; Jukema, J.W.; Niessen, H.W.M. & Quax, P.H.A. (2011), Toll-Like Receptor 4 Is Involved in Human and Mouse Vein Graft Remodeling, and Local Gene Silencing Reduces Vein Graft Disease in Hypercholesterolemic APOE*3Leiden Mice, Arteriosclerosis, Thrombosis, and Vascular Biology 31(5): 1033U190.
- Ewing, M.M.; Pettersson, K.; Karper, J.C.; Vries, M.R. de; Sampietro, M.L.; Jukema, J.W. & Quax, P.H. (2011), ANNEXIN A5 PREVENTS REACTIVE STENOSIS IN A DOSE-DEPENDENT FASHION: POTENTIAL FOR CLINICAL APPLICATION, Atherosclerosis. Supplements 12(1): 82-82.
- Arslan, F.; Smeets, M.B.; Vis, P.W.R.; Karper, J.C.; Quax, P.H.; Bongartz, L.G.; Peters, J.H.; Hoefer, I.E.; Doevendans, P.A.; Pasterkamp, G. & Kleijn, D.P. de (2011), Lack of Fibronectin-EDA Promotes Survival and Prevents Adverse Remodeling and Heart Function Deterioration After Myocardial Infarction, Circulation Research 108(5): 582U110.
- Vries, M.R. de; Wezel, A.; Schepers, A.; Kuiper, J.; Bot, I. & Quax, P.H.A. (2011), COMPLEMENT FACTOR C5A MODULATES VEIN GRAFT REMODELING AND ACCELERATED ATHEROSCLEROSIS VIA INTERFERENCE IN MAST CELL ACTIVATION, Atherosclerosis. Supplements 12(1): 79-79.
- Vries, M.R. de; Seghers, L.; Hoefer, I.E.; Pardali, E.; Hierck, B.P. van der; Goumans, M.J.; Dijke, P. ten & Quax, P.H. (2011), Endoglin and ALK1 Act Differently of Ischemia and Shear Stress Induced Neovascularization, Circulation 124(21).
- Pons, D.; Trompet, S.; Craen, A.J.M. de; Thijssen, P.E.; Quax, P.H.A.; Vries, M.R. de; Wierda, R.J.; Elsen, P.J. van den; Monraats, P.S.; Ewing, M.M.; Heijmans, B.T.; Slagboom, P.E.; Zwinderman, A.H.; Doevendans, P.A.F.M.; Tio, R.A.; Winter, R.J. de; Maat, M.P.M. de; Iakoubova, O.A.; Sattar, N.; Shepherd, J.; Westendorp, R.G.J.; Jukema, J.W.; PROSPER Study Grp; WOSCOPS Study Grp & GENDER Study Grp (2011), Genetic variation in PCAF, a key mediator in epigenetics, is associated with reduced vascular morbidity and mortality: evidence for a new concept from three independent prospective studies, Heart 97(2): 143-150.
- Verschuren, J.J.W.; Sampietro, M.L.; Pons, D.; Trompet, S.; Ewing, M.M.; Quax, P.H.A.; Knijff, P. de; Zwinderman, A.H.; Winter, R.J. de; Tio, R.A.; Maat, M.P. de; Doevendans, P.A.F.M. & Jukema, J.W. (2011), Matrix metalloproteinases 2 and 3 gene polymorphisms and the risk of target vessel revascularization after percutaneous coronary intervention: Is there still room for determining genetic variation of MMPs for assessment of an increased risk of restenosis?, Disease Markers 29(5): 265-273.
- Ahmed, T.A.N.; Bergheanu, S.C.; Stijnen, T.; Plevier, J.W.M.; Quax, P.H.A. & Jukema, J.W. (2011), Clinical outcomes of biodegradable-polymer drug eluting stents, a meta-analysis and systematic review of randomized and observational studies, European Heart Journal 32: 410-410.
- Vries, M.R. de; Seghers, L.; Bergen, J. van; Toes, R.E. & Quax, P.H. (2011), C57BL/6 Nk Cell Gene Complex Crucially Involved in Vascular Remodeling and Intimal Hyperplasia, Circulation 124(21).
- Karper, J.C.; Ewing, M.M.; Vries, M.R. de; Monica, N. la; Hamming, J.F.; Jukema, J.W. & Quax, P.H. (2011), Tlr7/9 Activation Enhances Neointima Formation in Hypercholesterolemic Apoe*3Leiden Mice, Circulation 124(21): -.
- Nossent, A.Y.; Hansen, J.L.; Doggen, C.; Quax, P.H.A.; Sheikh, S.P. & Rosendaal, F.R. (2011), SNPs in MicroRNA Binding Sites in 3 '-UTRs of RAAS Genes Influence Arterial Blood Pressure and Risk of Myocardial Infarction, American Journal of Hypertension 24(9): 999-1006.
- Karper, J.C.; Ewing, M.M.; Arens, R.; Jong, R.C. de; Peters, E.A.; Abdul, S.; Vries, M.R. de; Redeker, A.; Toes, R.E.; Jukema, J.W. & Quax, P.H. (2011), T Cell Co-Stimulation by CD28-CD80/86 and Its Negative Regulator CTLA-4 strongly Influence Accelerated Atherosclerosis Development, Circulation 124(21): -.
- Wierda, R.J.; Kuipers, H.F.; Eggermond, M.C.J.A. van; Benard, A.; Leeuwen, J.C. van; Carluccio, S.; Geutskens, S.B.; Jukema, J.W.; Marquez, V.E.; Quax, P.H.A. & Elsen, P.J. van den (2011), Epigenetic control of CCR5 transcript levels in immune cells and modulation by small molecules inhibitors.
- Bastiaansen, A.J.N.M.; Ewing, M.M.; Nossent, A.Y.; Peters, H.A.B.; Vries, M.R. de; Oeveren-Rietdijk, A.M. van; Boer, H.C. de; Zonneveld, A.J. van & Quax, P.H.A. (2011), Epigenetic Regulation By PCAF Moderates Arteriogenesis, Circulation 124(21): -.
- Bastiaansen, A.J.N.M.; Karper, J.C.; Nossent, A.Y.; Peters, H.A.B.; Vries, M.R. de; Oeveren-Rietdijk, A.M. van; Boer, H.C. de; Zonneveld, A.J. van & Quax, P.H.A. (2011), Tlr Accessory Molecule RP105 (CD180) Modulates Monocyte Activation and Moderates Arteriogenesis, Circulation 124(21): -.
- Ewing, M.M.; Karabina, S.A.; Nordzell, M.; Karper, J.C.; Atout, R.; Vries, M.R. de; Sexton, D.; Lettesjo, H.; Dahlbom, I.; Camber, O.; Frostegard, J.; Ninio, E.; Jukema, J.W.; Pettersson, K. & Quax, P.H. (2011), RECOMBINANT ANTI-PHOSPHORYLCHOLINE IGG ANTIBODIES PREVENT POST-INTERVENTIONAL ACCELERATED ATHEROSCLEROTIC VASCULAR REMODELING, Atherosclerosis. Supplements 12(1): 78-78.
- Quax, P. (2011), The interaction between monocytes and lymphocytes in arteriogenesis, Journal of Vascular Research 48: 329-329.
- Karper, J.C.; Jager, S.C. de; Ewing, M.; Jukema, J.W.; Kuiper, J. & Quax, P.H. (2011), RP105, A Cell Surface TLR4 Signaling Regulator, Enhances Atherosclerotic Plaque Formation, Circulation 124(21): -.
- Ahmed, T.A.N.; Bergheanu, S.C.; Stijnen, T.; Plevier, J.W.M.; Quax, P.H.A. & Jukema, J.W. (2011), Clinical performance of drug-eluting stents with biodegradable polymeric coating: a meta-analysis and systematic review, Eurointervention 7(4): 505-516.
- Krijnen, P.; Kupreishvili, K.; Vries, M. de; Schepers, A.; Stooker, W.; Vonk, A.; Eijsman, L.; Hinsbergh, V. van; Zeerleder, S.; Wouters, D.; Ham, M. van; Quax, P. & Niessen, H. (2011), C1-esterase inhibitor protects against early vein graft Remodelling under arterial blood pressure, Journal of Vascular Research 48: 132-132.
- Hengel, L.G. van den; Hellingman, A.A.; Boer, H.C. de; Oeveren-Rietdijk, A.M. van; Spek, C.A.; Zonneveld, A.J. van; Reitsma, P.H.; Hamming, J.F.; Quax, P.H.A. & Versteeg, H.H. (2011), PAR-2, but not PAR-1, is critically involved in collateral formation in a mouse hind limb ischemia model, Journal of Thrombosis and Haemostasis 9: 953-953.
- Willems, S.; Vink, A.; Hoefer, I.; Quax, P.; Borst, G.J. de; Kleijn, D. de & Pasterkamp, G. (2011), Patients with high intraplaque mast cell numbers have an increased risk for future cardiovascular events, European Heart Journal 32: 489-489.
- Ewing, M.M.; Vries, M.R. de; Nordzell, M.; Pettersson, K.; Boer, H.C. de; Zonneveld, A.J. van; Frostegard, J.; Jukema, J.W. & Quax, P.H.A. (2011), Annexin A5 Therapy Attenuates Vascular Inflammation and Remodeling and Improves Endothelial Function in Mice, Arteriosclerosis, Thrombosis, and Vascular Biology 31(1): 95+.
- Boonstra, M.C.; Verspaget, H.W.; Ganesh, S.; Kubben, F.J.G.M.; Vahrmeijer, A.L.; Velde, C.J.H.V. de; Kuppen, P.J.K.; Quax, P.H.A. & Sier, C.F.M. (2011), Clinical Applications of the Urokinase Receptor (uPAR) for Cancer Patients, Current Pharmaceutical Design 17(19): 1890-1910.
- Vries, M.R. de; Niessen, H.W.M.; Lowik, C.W.; Jukema, J.W. & Quax, P.H.A. (2011), SPONTANEOUS PLAQUE DISRUPTIONS, DISSECTION, EROSION AND INTRAPLAQUE HEMORRHAGE IN MURINE VEIN GRAFTS CAN BE ATTENUATED BY TIMP-1 OVEREXPRESSION, Atherosclerosis. Supplements 12(1): 63-63.
- Laan, A. van der; Schirmer, S.; Vries, M. de; Koning, J.; Volger, O.; Fledderus, J.; Quax, P.; Piek, J.; Horrevoets, A. & Royen, N. van (2010), Galectin-2 expression is dependent on the rs7291467 single nucleotide polymorphism and suppresses collateral artery growth, European Heart Journal 31: 319-320.
- Karper, J.C.; Vries, M.R. de; Brand, B. van den; Hoefer, I.E.; Niessen, H.W. & Quax, P.H. (2010), TLR4 Is a Potential Local Therapeutic Target Against Vein Graft Disease, Arteriosclerosis, Thrombosis, and Vascular Biology 30(11): E311-E311.
- Taherzadeh, Z.; VanBavel, E.; Vos, J. de; Matlung, H.L.; Montfrans, G. van; Brewster, L.M.; Seghers, L.; Quax, P.H.A. & Bakker, E.N.T.P. (2010), Strain-dependent susceptibility for hypertension in mice resides in the natural killer gene complex, AJP - Heart and Circulatory Physiology 298(4): H1273H1282.
- Ewing, M.; Vries, M.R. de; Nordzell, M.; Pettersson, K.; Frostegard, J.; Jukema, J.W. & Quax, P.H.A. (2010), Annexin A5 therapy attenuates vascular inflammation and remodeling and improves endothelial function in mice, European Heart Journal 31: 830-830.
- Ewing, M.M.; Verschuren, J.J.W.; Sampietro, M.L.; Vries, M.R. de; Knijff, P. de; Quax, P.H.A. & Jukema, J.W. (2010), Annexin A5: genotypic risk marker for clinical restenosis after percutaneous coronary intervention, European Heart Journal 31: 803-803.
- Ewing, M.M.; Vries, M.R. de; Pettersson, K.; Frostegard, J.; Sexton, D.J.; Jukema, J.W. & Quax, P.H.A. (2010), Passive immunization with anti-phosphorylcholine IgG antibodies reduces neointimal formation and vascular inflammation in a mouse model for accelerated atherosclerosis, European Heart Journal 31: 158-158.
- Waard, V. de; Bot, I.; Jager, S.C.A. de; Talib, S.; Egashira, K.; Vries, M.R. de; Quax, P.H.A.; Biessen, E.A.L. & Berkel, T.J.C. van (2010), Systemic MCP1/CCR2 blockade and leukocyte specific MCP1/CCR2 inhibition affect aortic aneurysm formation differently, Atherosclerosis 211(1): 84-89.
- Solingen, C. van; Monge, M.; Vries, D.K. de; Seghers, L.; Vries, M.R. de; Bijkerk, R.; Oeveren-Rietdijk, A.M. van; Veer, E.P. van der; Quax, P.H.; Schaapherder, A.F.; Boer, H.C. de; Rabelink, T.J. & Zonneveld, A.J. van (2010), Silencing of Endothelial Cell-Enriched MicroRNA-126 Is Associated with Elevated SDF-1 and VEGF-A Levels and the Increase of Sca-1(+) Progenitor Cells After Ischemia Reperfusion Injury, Arteriosclerosis, Thrombosis, and Vascular Biology 30(11): E279E279.
- Eefting, D.; Vries, M.R. de; Grimbergen, J.M.; Karper, J.C.; Bockel, J.H. van & Quax, P.H.A. (2010), In vivo suppression of vein graft disease by nonviral, electroporation-mediated, gene transfer of tissue inhibitor of metalloproteinase-1 linked to the amino terminal fragment of urokinase (TIMP-1.ATF), a cell-surface directed matrix metalloproteinase inhibitor, Journal of Vascular Surgery 51(2): 429-437.
- Bogt, K.E.A. van der; Hellingman, A.A.; Lijkwan, M.A.; Bos, E.J.; Vries, M.R. de; Fischbein, M.; Quax, P.H.A.; Robbins, R.C.; Wu, J.C. & Hamming, J.F. (2010), In vivo visualization of transplanted bone marrow mononuclear cell behavior in murine peripheral artery occlusive disease, British Journal of Surgery 97: S9S9.
- Hellingman, A.A.; Geutskens, S.B.; Seghers, L.; Vries, M.R. de; Zonneveld, A.J. van; Schoot, C.E. van der; Hamming, J.F.; Quax, P.H.A. & Zwaginga, J.J. (2010), Monocytes as cellular therapy for vascular regeneration, British Journal of Surgery 97: S37S37.
- Karper, J.C.; Vries, M.R. de; Brand, B. van den; Hoefer, I.M.; Jukema, J.W.; Niessen, H.W.M. & Quax, P.H.A. (2010), Local silencing of toll like receptor 4 to improve vein graft survival, European Heart Journal 31: 1019-1020.
- Solingen, C. van; Monge, M.; Vries, D.K. de; Seghers, L.; Vries, M.R. de; Bijkerk, R.; Oeveren-Rietdijk, A.M. van; Veer, E.P. van der; Quax, P.H.A.; Schaapherder, A.F.M.; Boer, H.C. de; Rabelink, A.J. & Zonneveld, A.J. van (2010), SILENCING OF ENDOTHELIAL CELL ENRICHED MICRORNA-126 IS ASSOCIATED WITH ELEVATED SDF-1 LEVELS AND THE INCREASE OF SCA-1+PROGENITOR CELLS AFTER ISCHEMIA REPERFUSION INJURY, Hypertension 56(6): 1167-1167.
- Hellingman, A.A.; Bastiaansen, A.J.N.M.; Vries, M.R. de; Seghers, L.; Jukema, J.W.; Hamming, J.F. & Quax, P.H.A. (2010), Induction of hind limb ischemia in mice: comparison of different models for therapeutic arteriogenesis, British Journal of Surgery 97: S85S85.
- Vries, M. de; Bot, I.; Heijden, T. van der; Schepers, A. & Quax, P. (2010), Complement Factor C5a Modulates Vein Graft Thickening and Accelerated Atherosclerosis in a Murine Model of Vein Graft Disease via Interference in Mast Cell Activation, Circulation 122(21).
- Karper, J.C.; Ewing, M.M.; Vries, M.R. de; Sampietro, M.L.; Jukema, J.W. & Quax, P.H.A. (2010), RP105, a Toll Like Receptor 4 (TLR4) homolog, moderates restenosis and outward remodeling., Circulation 122(21).
- Wierda, R.J.; Geutskens, S.B.; Jukema, J.W.; Quax, P.H.A. & Elsen, P.J. van den (2010), Epigenetics in atherosclerosis and inflammation, Journal of Cellular and Molecular Medicine 14(6): 1225-1240.
- Pols, T.W.H.; Bonta, P.I.; Pires, N.M.M.; Otermin, I.; Vos, M.; Vries, M.R. de; Eijk, M. van; Roelofsen, J.; Havekes, L.M.; Quax, P.H.A.; Kuilenburg, A.B.P. van; Waard, V. de; Pannekoek, H. & Vries, C.J.M. de (2010), 6-Mercaptopurine Inhibits Atherosclerosis in Apolipoprotein E*3-Leiden Transgenic Mice Through Atheroprotective Actions on Monocytes and Macrophages, Arteriosclerosis, Thrombosis, and Vascular Biology 30(8): 1591U184.
- Ewing, M.; Karabina, S.; Pettersson, K.; Atout, R.; Vries, M. de; Sexton, D.; Lettesjo, H.; Frostegard, J.; Jukema, J.W.; Ninio, E. & Quax, P. (2010), Anti-Phosphorylcholine IgG Antibodies Reduce Restenosis and Vascular Inflammation by Inhibition of the Unfolded Protein Response in a Mouse Model of Accelerated Atherosclerosis, Circulation 122(21).
- Veer, E.P. van der; Kraaijeveld, A.O.; Pons, D.; Vries, M.R. de; Segers, F.M.; Santbrink, P.M. van; Berkel, T.J. van; Quax, P.H.; Zonneveld, A.J. van; Jukema, W. & Biessen, E.A. (2010), Perturbation of the mRNA-Binding Protein Quaking Induces Vascular Smooth Muscle Cell Dysfunction and Associates with Clinical Restenosis After Percutaneous Coronary Intervention, Arteriosclerosis, Thrombosis, and Vascular Biology 30(11): E254E254.
- Eefting, D.; Seghers, L.; Grimbergen, J.M.; Vries, M.R. de; Boer, H.C. de; Lardenoye, J.W.H.P.; Jukema, J.W.; Bockel, J.H. van & Quax, P.H.A. (2010), A novel urokinase receptor-targeted inhibitor for plasmin and matrix metalloproteinases suppresses vein graft disease, Cardiovascular Research 88(2): 367-375.
- Hellingman, A.A.; Bastiaansen, A.J.N.M.; Vries, M.R. de; Seghers, L.; Lijkwan, M.A.; Lowik, C.W.; Hamming, J.F. & Quax, P.H.A. (2010), Variations in Surgical Procedures for Hind Limb Ischaemia Mouse Models Result in differences in Collateral Formation.
- Monraats, P.S.; Fang, Y.; Pons, D.; Pires, N.M.M.; Pols, H.A.P.; Zwinderman, A.H.; Maat, M.P.M. de; Doevendans, P.A.F.; Dewinter, R.J.; Tio, R.A.; Waltenberger, J.; Frants, R.R.; Quax, P.H.A.; Laarse, A. van der; Wall, E.E. van der; Uitterlinden, A.G. & Jukema, J.W. (2010), Vitamin D receptor: a new risk marker for clinical restenosis after percutaneous coronary intervention, Expert Opinion on Therapeutic Targets 14(3): 243-251.
- Laan, A.M. van der; Schirmer, S.H.; Vries, M.R. de; Koning, J.J.; Volger, O.L.; Fledderus, J.O.; Quax, P.H.; Piek, J.J.; Horrevoets, A.J. & Royen, N. van (2010), Galectin-2 Expression is Dependent on the rs7291467 Single Nucleotide Polymorphism and Inhibits Collateral Artery Growth, Circulation 122(21).
- Stone OA, Richer C, Emanueli C, van Weel V, Quax PHA, Katare R, Kraenkel N, Campagnolo P, Barcelos LS & Siragusa M (2009), Critical Role of Tissue Kallikrein in Vessel Formation and Maturation Implications for Therapeutic Revascularization, Arteriosclerosis, Thrombosis, and Vascular Biology 29(5): 657U91.
- Ewing MM, de Vries M, Nordzell M, Jukema JW, Frostegard J, Pettersson K & Quax P (2009), Annexin A5 Reduces Inflammation Mediated Vascular Remodelling and Post-interventional Atherosclerosis and Improves Vascular Function in Hypercholesterolemic Mice, Circulation 120(18): S1113S1113.
- Pons D, de Vries FR, van den Elsen PJ, Heijmans BT, Quax PH & Jukema JW (2009), Epigenetic histone acetylation modifiers in vascular remodelling: new targets for therapy in cardiovascular disease, European Heart Journal 30(3): 266-277.
- Taherzadeh Z, vanBavel E, de Vos J, Matlung H, van Montfrans G, Brewster L, Seghers L, Quax PHA & Bakker ENTP (2009), Strain-dependent Susceptibility for Hypertension in Mice Resides in the Natural Killer Gene Complex, Circulation 120(18): S1111S1111.
- Geutskens SB, Hellingman AW, van Beem RT, Seghers L, de Vries MR, van Zonneveld AJ, van den Elsen PJ, van der Schoot CE, Quax PHA & Zwaginga JJ (2009), TRANSFUSION OF PRO-ARTERIOGENIC MONOCYTES AS CELLULAR THERAPY FOR VASCULAR REGENERATION, Experimental Hematology 37(9): S8S8.
- Eefting D, Bot I, de Vries MR, Schepers A, van Bockel JH, van Berkel TJC, Biessen EAL & Quax PHA (2009), Local lentiviral short hairpin RNA silencing of CCR2 inhibits vein graft thickening in hypercholesterolemic apolipoprotein E3-Leiden mice, Journal of Vascular Surgery 50(1): 152-160.
- Karper J, de Vries M, van den Brand B, Niessen H, Hoeffer I & Quax P (2009), Local Gene Silencing of TLR4 Expression in vivo Improves Vein Graft Patency in Mice, Circulation 120(18): S1138S1138.
- Van Der Bogt KE, Hellingman AA, Lijkwan MA, Bos EJ, de Vries MR, Fischbein MP, Quax PH, Robbins RC, Hamming JF & Wu JC (2009), Molecular Imaging of Bone Marrow Mononuclear Cell Survival and Homing in Murine Peripheral Artery Occlusive Disease, Circulation 120(18): S1131S1131.
- Seghers L, van Weel V, van Bergen J, Toes R, Hellingman A, de Vries M, van Hinsbergh V & Quax P (2009), C57BL/6 NK Cell Gene Complex Crucially Involved in General Vascular Remodelling, Circulation 120(18): S1146S1146.
- Taherzadeh Z., VanBavel E., deVos J., Matlung H. L., vanMontfrans G., Brewster L. M., Seghers L., Quax P. H. A. & Bakker E. N. T. P. (2009), STRAIN-DEPENDENT SUSCEPTIBILITY FOR HYPERTENSION IN MICE RESIDES IN THE NATURAL KILLER GENE COMPLEX, Hypertension 54(5): 1187-1187.
- Ewing M., de Vries M., Nordzell M., Pettersson K., Jukema J. & Quax P. (2009), THERAPEUTIC EFFECTS OF ANNEXIN A5 ON ACCELERATED ATHEROSCLEROSIS IN VEIN GRAFTS IN HYPERCHOLESTEROLEMIC MICE, Atherosclerosis. Supplements 10(2).
- van Solingen C, Seghers L, Bijkerk R, Duijs JMGJ, Roeten MK, van Oeveren-Rietdijk AM, Baelde HJ, Monge M, Vos JB & de Boer HC (2009), Antagomir-mediated silencing of endothelial cell specific microRNA-126 impairs ischemia-induced angiogenesis, Journal of Cellular and Molecular Medicine 13(8A): 1577-1585.
- Pols TWH, Ottenhoff R, Vos M, Levels JHM, Quax PHA, Meijers JCM, Pannekoek H, Groen AK & de Vries CJM (2008), Nur77 modulates hepatic lipid metabolism through suppression of SREBP1c activity, Biochemical and Biophysical Research Communications 366(4).
- Kupreishvili K, ter Weeme M, Morre SA, van den Brule AJC, Huybregts MAJM, Quax PHA, ten Velden J, van Hinsbergh VWM, Stooker W, Eijsman L & Niessen HWM (2008), Increased infiltration of Chlamydophila pneumoniae in the vessel wall of human veins after perfusion, European Journal of Clinical Investigation 38(7).
- van Weel V, van Tongeren RB, van Hinsbergh VWM, van Bockel JH & Quax PHA (2008), Vascular growth in ischemic limbs: A review of mechanisms and possible therapeutic stimulation, Annals of Vascular Surgery 22(4).
- Mayr M, Zampetaki A, Sidibe A, Mayr U, Yin XK, De Souza AI, Chung YL, Madhu B, Quax PH, Hu YH, Griffiths JR & Xu QB (2008), Proteomic and metabolomic analysis of smooth muscle cells derived from the arterial media and adventitial progenitors of apolipoprotein E-deficient mice, Circulation Research 102(9).
- Timmers L, Sluijter JPG, van Keulen JK, Hoefer IE, Nederhoff MGJ, Goumans MJ, Doevendans PA, van Echteld CJA, Joles JA, Quax PH, Piek JJ, Pasterkamp G & de Kleijn DPV (2008), Toll-like receptor 4 mediates maladaptive left ventricular remodeling and impairs cardiac function after myocardial infarction, Circulation Research 102(2).
- van der Hoeven BL, Pires NMM, Warda HM, Putter H, Quax PHA, Schalij MJ & Jukema JW (2008), Dexamethasone-eluting stents for the prevention of in-stent restenosis: Evidence for a differential effect in insulin-dependent and non-insulin-dependent diabetic patients, International Journal of Cardiology 124(2).
- van Oostrom MC, van Oostrom O, Quax PHA, Verhaar MC & Hoefer IE (2008), Insights into mechanisms behind arteriogenesis: what does the future hold?, Journal of Leukocyte Biology 84(6).
- Quax P. H. A., De Vries M. R., Von der Thuesen J. H., Eefting D. & Jukema J. W. (2008), Spontaneous dissection and rupture in vein grafts in hypercholesterolemic ApoE3-leiden mice can be prevented by over expression of TIMP-1, European Heart Journal 29: 235-235.
- Hauer A.D., Puijvelde G.H.M. van, Peterse N., Vos P. de, Weel V. van, Wanrooij E.J. van, Biessen E.A., Quax P.H., Niethammer A.G., Reisfeld R.A., Berkel T.J.C. van & Kuiper J. (2007), Vaccination against VEGFR2 attenuates initiation and progression of atherosclerosis, Arteriosclerosis, Thrombosis, and Vascular Biology 27(9): 2050-2057.
- Nijhuis MMO, van Keulen JK, Pasterkamp G, Quax PH & de Kleijn DPV (2007), Activation of the innate immune system in atherosclerotic disease, Current Pharmaceutical Design 13(10).
- Pires NMM, Eefting D, de Vries MR, Quax PHA & Jukema JW (2007), Sirolimus and paclitaxel provoke different vascular pathological responses after local delivery in a murine model for restenosis on underlying atherosclerotic arteries, Heart 93(8).
- Pons D, Monraats PS, de Maat MPM, Pires NMM, Quax PHA, van Vlijmen BJM, Rosendaal FR, Zwinderman AH, Doevendans PAFM, Waltenberger J, Winter RJ, Tio RA, Frants RR, van der Laarse A, van der Wall EE & Jukema JW (2007), The influence of established genetic variation in the haemostatic system on clinical restenosis after percutaneous coronary interventions, Thrombosis and Haemostasis 98(6).
- Krom YD, Pires NMM, Jukema JW, de Vries MR, Frants RR, Havekes LM, van Dijk KW & Quax PHA (2007), Inhibition of neointima formation by local delivery of estrogen receptor alpha and beta specific agonists, Cardiovascular Research 73(1).
- Pires NMM, Pols TWH, de Vries MR, van Tiel CM, Bonta PI, Vos M, Arkenbout EK, Pannekoek H, Jukema JW, Quax PHA & de Vries CJM (2007), Activation of nuclear receptor Nur77 by 6-mercaptopurine protects against neointima formation, Circulation 115(4).
- van Weel V, Seghers L, Toes R, van Bockel H & Quax P (2007), Natural killer and CD4+T lymphocytes play a dominant role in collateral artery development, Inflammation Research 56.
- Eefting D, Grimbergen JM, De Vries MR, Van Weel V, Kaijzel EL, Que I, Moon RT, Lowik CW, Van Bockel JH & Quax PHA (2007), Prolonged in vivo gene silencing by electroporation-mediated plasmid delivery of small interfering RNA, Human Gene Therapy 18(9).
- Hauer AD, van Puijvelde GHM, Peterse N, de Vos P, van Weel V, van Wanrooij EJA, Biessen EAL, Quax PHA, Niethammer AG, Reisfeld RA, van Berkel TJC & Kuiper J (2007), Vaccination against VEGFR2 attenuates initiation and progression of atherosclerosis, Arteriosclerosis, Thrombosis, and Vascular Biology 27(9).
- Monraats, P.S.; Kurreeman, F.A.S.; Pons, D.; Sewgobind, V.D.K.D.; Vries, F.R. de; Zwinderman, A.H.; Maat, M.P.M. de; Doevendans, P.A.; Winter, R.J. de; Tio, R.A.; Waltenberger, J.; Huizinga, T.W.J.; Eefting, D.; Quax, P.H.A.; Frants, R.R.; Laarse, A. van der; Wall, E.E. van der & Jukema, J.W. (2007), Interleukin 10: a new risk marker for the development of restenosis after percutaneous coronary intervention, Genes and Immunity 8(1).
- van Bezooijen RL, Svensson JP, Eefting D, Visser A, van der Horst G, Karperien M, Quax PH, Vrieling H, Papapoulos SE, ten Dijke P & Lowik CW (2007), Wnt but not BMP signaling is involved in the inhibitory action of sclerostin on BMP-stimulated bone formation, Journal of Bone and Mineral Research 22(1).
- Eefting D, Schepers A, De Vries MR, Pires NMM, Grimbergen JM, Lagerweij T, Nagelkerken LM, Monraats PS, Jukema JW, van Bockel JH & Quax PHA (2007), The effect of interleukin-10 knock-out and overexpression on neointima formation in hypercholesterolemic APOE*3-Leiden mice, Atherosclerosis 193(2).
- van Weel V, Seghers L, de Vries MR, Kuiper EJ, Schlingemann RO, Bajema IM, Lindeman JHN, Diemen PMDV, van Hinsbergh VWM, van Bockel JH & Quax PHA (2007), Expression of vascular endothelial growth factor, stromal cell-derived factor-1, and CXCR4 in human limb muscle with acute and chronic ischemia, Arteriosclerosis, Thrombosis, and Vascular Biology 27(6).
- van Weel V, Toes REM, Seghers L, Deckers MML, de Vries MR, Eilers PH, Sipkens J, Schepers A, Eefting D, van Hinsbergh VWM, van Bockel JH & Quax PHA (2007), Natural killer cells and CD4(+) T-Cells modulate collateral artery development, Arteriosclerosis, Thrombosis, and Vascular Biology 27(11).
- Quax Paul, Schepers A., de Vries M. & van Bockel H. (2007), Blocking complement inhibits vascular remodeling and accelerated atherosclerosis in murine vein grafts, Inflammation Research 56: S386-S386.
- Mayr Manuel, Zampetaki Anna, Sidbe Anissa, Yin Xiaolke, Madhu Basetti, Quax Paul H., Chung Yuen-Li, Griffiths John R. & Xu Oingbo (2007), Proteomic and metabolomic analysis of smooth muscle cells derived from adventitial progenitors of apolipoprotein E-deficient mice, Circulation 116(16): 267-267.
- Bonta Peter I., Pols Thijs W., van Tiel Claudia M., Pires Nuno M., Bakker Erik N., Quax Paul H. & de Vries Carlie J. (2007), Nuclear receptor Nur77 protective in arterial remodeling and vascular disease, Circulation 116(16): 44-44.
- van Weel V, de Vries M, Voshol PJ, Verloop RE, Eilers PHC, van Hinsbergh VWM, van Bockel JH & Quax PHA (2006), Hypercholesterolemia reduces collateral artery growth more dominantly than hyperglycemia or insulin resistance in mice, Arteriosclerosis, Thrombosis, and Vascular Biology 26(6).
- Verhaagh S, de Jong E, Goudsmit J, Lecollinet S, Gillissen G, de Vries M, van Leuven K, Que I, Ouwehand K, Mintardjo R, Weverling GJ, Radosevic K, Richardson J, Eloit M, Lowik C, Quax P & Havenga M (2006), Human CD46-transgenic mice in studies involving replication-incompetent adenoviral type 35 vectors, Journal of General Virology 87.
- Schepers A, de Vries MR, van Leuven CJ, Grimbergen JM, Holers VM, Daha MR, van Bockel JH & Quax PHA (2006), Inhibition of complement component C3 reduces vein graft atherosclerosis in apolipoprotein E3-Leiden transgenic mice, Circulation 114(25).
- de Waard V, Arkenbout EK, Vos M, Mocking AIM, Niessen HWM, Stooker W, de Moo BAJM, Quax PHA, Bakker ENTP, VanBavel E, Pannekoek H & de Vries CJM (2006), TR3 nuclear orphan receptor prevents cyclic stretch-induced proliferation of venous smooth muscle cells, American Journal of Pathology 168(6).
- van Hinsbergh VWM, Engelse MA & Quax PHA (2006), Pericellular proteases in angiogenesis and vasculogenesis, Arteriosclerosis, Thrombosis, and Vascular Biology 26(4).
- Kusumanto YH, Van Weel V, Mulder NH, Smit AJ, Van den Dungen JJAM, Hooymans JMM, Sluiter WJ, Tio RA, Quax PHA, Gans ROB, Dullaart RPF & Hospers GAP (2006), Treatment with intramuscular vascular endothelial growth factor gene compared with placebo for patients with diabetes mellitus and critical limb ischemia: A double-blind randomized trial, Human Gene Therapy 17(6).
- Madeddu P, Emanueli C, Spillmann F, Meloni M, Bouby N, Richer C, Alhenc-Gelas F, Van Weel V, Eefting D, Quax PHA, Hu Y, Xu Q, Hemdahl AL, van Golde J, Huijberts M, de Lussanet Q, Boudier HS, Couffinhal T, Duplaa C, Chimenti S, Staszewsky L, Latini R, Baumans V & Levy BI (2006), Murine models of myocardial and limb ischemia: Diagnostic end-points and relevance to clinical problems, Vascular Pharmacology 45(5): 281-301.
- Schepers A, Pires NMM, Eefting D, de Vries MR, van Bockel JH & Quax PHA (2006), Short-term dexamethasone treatment inhibits vein graft thickening in hypcrcholcstcrolemic ApoE3Leiden transgenic mice, Journal of Vascular Surgery 43(4).
- Pires NMM, Jukema JW, Daemen MJAP & Quax PHA (2006), Drug-eluting stents studies in mice: Do we need atherosclerosis to study restenosis?, Vascular Pharmacology 44(5).
- Lemckert AAC, Grimbergen J, Smits S, Hartkoorn E, Holterman L, Berkhout B, Barouch DH, Vogels R, Quax P, Goudsmit J & Havenga MJE (2006), Generation of a novel replication-incompetent adenoviral vector derived from human adenovirus type 49: manufacture on PER.C6 cells, tropism and immunogenicity, Journal of General Virology 87.
- Schepers A, Eefting D, Bonta PI, Grimbergen JM, de Vries MR, van Weel V, de Vries CJ, Egashira K, van Bockel JH & Quax PHA (2006), Anti-MCP-1 gene therapy inhibits vascular smooth muscle cells proliferation and attenuates vein graft thickening both in vitro and in vivo, Arteriosclerosis, Thrombosis, and Vascular Biology 26(9).
- Pires N. M. M., Eefting D., De Vries M. R., Quax P. H. A. & Jukema J. W. (2006), Differential vascular pathology and transcriptional responses of rapamycin and paclitaxel to inhibit restenosis, European Heart Journal 27: 369-369.
- Bot Ilze, Eefting Daniel, De Vries Margreet R., Van Bockel Hajo, Van Berkel Theo J., Biessen Erik A. & Quax Paul H. (2006), Local lentiviral ShRNA mediated silencing of CCR2 inhibits intimal hyperplasia in ApoE3Leiden mice, Circulation 114(18): 122-123.
- Quax P. H. A. (2006), Potential side effects of pro-angiogenic therapies, Journal of Vascular Research 43: 28-28.
- Eefting D., Bot I., De Vries M. R., Van Bockel J. H., Van Berkel T. J. C., Biessen E. A. L. & Quax P. H. A. (2006), Local lentiviral shRNA silencing of CCR2 inhibits vein graft thickening in hypercholesterolemic ApoE3Leiden mice, European Heart Journal 27: 5-5.
- van Weel Vincent, Toes Rene, Deckers Martine, de Vries Margreet, Schepers Abbey, Eefting Daniel, van Hinsbergh Victor, van Bockel Hajo & Quax Paul (2006), Natural killer en CD4+T-lymphocytes modulate collateral artery growth, Vascular Pharmacology 45(3): 183-183.
- Hauer A. D., Van Es T., De Vos P., Quax P. H. A., Van Berkel T. J. C., Reisfeld R. A. & Kuiper J. (2006), Vaccination against VEGFR2 attenuates both the initiation and progression of atherosclerosis, Atherosclerosis. Supplements 7(3): 33-33.
- Lemckert Angelique, Grimbergen Jos, Thorner Anna, Vogels Ronald, Quax Paul, Goudsmit Jaap, Barouch Dan & Havenga Menzo (2006), A Novel Replication Incompetent Human Subgroup D Adenoviral Vector Based on Type 49: Manufacture on PER.C6 (R), Cell Tropism and Immunogenicity, Molecular Therapy 13: S230-S230.
- Pires Nuno M., Pols Thijs W., de Vries Margreet R., van Tiel Claudia M., Bonta Peter I., Vos Mariska, Arkenbout E. Karin, Pannekoek Hans, Jukema J. Wouter, Quax Paul H. & de Vries Carlie J. (2006), Activation of nuclear orphan receptor Nur77 by 6-mercaptopurine protects against neointima formation, Circulation 114(18): 70-70.
- Pires NMM, Schepers A, van der Hoeven BL, de Vries MR, Boesten LSM, Jukema JW & Quax PHA (2005), Histopathologic alterations following local delivery of dexamethasone to inhibit restenosis in murine arteries, Cardiovascular Research 68(3).
- Eefting D, De Vries MR, Grimbergen JM, Van Bockel JH & Quax PH (2005), Non-viral, electroporation mediated gene transfer of TIMP-1.ATF, a cell-surface directed MMP inhibitor, suppresses intimal hyperplasia vein grafts more efficiently than TIMP-1 in vivo, Circulation 112(17).
- Lamfers MLM, Gianni D, Tung CH, Idema S, Schagen FHE, Carette JE, Quax PHA, Van Beusechem VW, Vandertop WP, Dirven CMF, Chiocca EA & Gerritsen WR (2005), Tissue inhibitor of metalloproteinase-3 expression from an oncolytic adenovirus inhibits matrix metalloproteinase activity In vivo without affecting antitumor efficacy in malignant glioma, Cancer Research 65(20).
- Monraats PS, Pires NMM, Agema WRP, Zwinderman AH, Schepers A, de Maat MPM, Doevendans PA, de Winter RJ, Tio RA, Waltenberger J, Frants RR, Quax PHA, van Vlijmen BJM, Atsma DE, van der Laarse A, van der Wall EE & Jukema JW (2005), Genetic inflammatory factors predict restenosis after percutaneous coronary interventions, Circulation 112(16).
- Eefting D, De Vries M, Grimbergen J, Van Bockel H & Quax P (2005), Non-viral, electroporation mediated gene transfer of TIMP-1.ATF, a cell-surface directed MMP inhibitor, suppresses intimal hyperplasia in vein grafts more efficiently than TIMP-1 in vivo., Journal of Vascular Research 42.
- Eefting D, De Vries M, Grimbergen J, Lardenoye JW, Van Bockel H & Quax P (2005), In vivo suppression of intimal hyperplasia in vein grafts by non-viral, electroporation mediated, gene transfer of ATF.BPTI, a cell-surface directed plasmin inhibitor., Journal of Vascular Research 42.
- Monraats PS, Rana JS, Nierman MC, Pires NMM, Zwinderman AH, Kastelein JJP, Kuivenhoven JA, de Maat MPM, Rittersma SZH, Schepers A, Doevendans PAF, de Winter RJ, Tio RA, Frants RR, Quax PHA, van Der Laarse A, van Der Wall EE & Jukema JW (2005), Lipoprotein lipase gene polymorphisms and the risk of target vessel revascularization after percutaneous coronary intervention, Journal of the American College of Cardiology 46(6).
- van der Hoeven BL, Pires NMM, Warda HM, Oemrawsingh PV, van Vlijmen BJM, Quax PHA, Schalij MJ, van der Wall EE & Jukema JW (2005), Drug-eluting stents: results, promises and problems, International Journal of Cardiology 99(1).
- Sluijter JPG, Verloop RE, Pulskens WPC, Velema E, Grimbergen JM, Quax PH, Goumans MJ, Pasterkamp G & de Kleijn DPV (2005), Involvement of furin-like proprotein convertases in the arterial response to injury, Cardiovascular Research 68(1).
- Pires NMM, van der Hoeven BL, de Vries MR, Havekes LM, van Vlijmen BJ, Hennink WE, Quax PHA & Jukema JW (2005), Local perivascular delivery of anti-restenotic agents from a drug-eluting poly(epsilon-caprolactone) stent cuff, Biomaterials 26(26).
- Drynda A, Quax PHA, Neumann M, van der Laan WH, Pap G, Drynda S, Meinecke I, Kekow J, Neumann W, Huizinga TWJ, Naumann M, Konig W & Pap T (2005), Gene transfer of tissue inhibitor of metalloproteinases-3 reverses the inhibitory effects of TNF-alpha on fas-induced apoptosis in rheumatoid arthritis synovial fibroblasts, Journal of Immunology 174(10).
- Monraats PS, Pireso NMM, Schepers A, Agema WRP, Boesten LSM, de Vries MR, Zwinderman AH, de Maat MPM, Doevendans PAFM, de Winter RJ, Tio RA, Waltenberger J, 't Hart LM, Frants RR, Quax PHA, van Vlijmen BJM, Havekes LM, van der Laarse A, van der Wall EE & Jukema JW (2005), Tumor necrosis factor-alpha plays an important role in restenosis development, FASEB Journal 19(14).
- Lamfers M, Gianni D, Tung CH, Idema S, Quax PH, van Beusechem VW, Vandertop WP, Dirven CMF, Chiocca EA & Gerritsen WR (2005), Tissue inhibitor of metalloproteinases-3 expression in the context of an oncolytic adenovirus inhibits matrix metalloproteinase activity in vivo but does not enhance antitumor efficacy in malignant glioma, Neuro-Oncology 7(3): 379-380.
- Pires NM, Monraats R, Schepers A, de Vries MR, van Bockel JH, Quax PH & Jukema JW (2005), Tumor necrosis factor-alpha plays a pivotal role in restenosis development, Atherosclerosis. Supplements 6(1): 39-40.
- Hauer AD, de Vos P, Peterse N, Weel V, Quax PH, van Puijvelde GH, van Berkel THJ, Reisfeld RA & Kuiper J (2005), Vaccination against VEGF receptor 2 blocks initiation and progression of atherosclerosis, Atherosclerosis. Supplements 6(1): 68-68.
- Pires, N.M.M.; Monraats, P.S.; Schepers, A.; Boesten, L.S.M.; Vlijmen, B.J.M. van; Havekes, L.M.; Quax, P.H.A. & Jukema, J.W. (2005), Pharmacological inhibition and genetic deficiency of tumour necrosis factor-alpha attenuates restenosis development, European Heart Journal 26: 238-238.
- Pires, N.M.; Monraats, P.S.; Schepers, A.; Boesten, L.S.; Vries, M.R. de; Vlijmen, B.J. van; Havekes, L.M.; Quax, P.H. & Jukema, W. (2005), Pharmacological modulation of tumor necrosis factor-alpha attenuates restenosis development, Circulation 112(17): U320-U320.
- DeRuiter MC, Quax PHA, VanMunsteren CJ, Aoyama N, Hierck BP & Groot ACG (2005), Endothelial proliferation, migration and transformation during the initial phases of intimal formation., Journal of Vascular Research 42: 69-69.
- Van Vlijmen BJ, Pires NM, Quax PH, Hennink WE, Havekes LM & Jukema JW (2004), A novel mouse model for rapid screening of antirestenotic drugs using a drug-eluting perivascular device, Arteriosclerosis, Thrombosis, and Vascular Biology 24(5).
- Young JL, Eefting D, Quax PHA & Dean DA (2004), Electroporation-mediated gene delivery to mouse femoral arteries in a model of vascular injury, Molecular Therapy 9.
- van Weel V, Deckers MML, Grimbergen JM, van Leuven KJM, Lardenoye JWHP, Schlingemann RO, Amerongen GPV, van Bockel JH, van Hinsbergh VWM & Quax PHA (2004), Vascular endothelial growth factor overexpression in ischemic skeletal muscle enhances myoglobin expression in vivo, Circulation Research 95(1).
- Holterman L, Vogels R, van der Vlugt R, Sieuwerts M, Grimbergen J, Kaspers J, Geelen E, van der Helm E, Lemckert A, Gillissen G, Verhaagh S, Custers J, Zuijdgeest D, Berkhout B, Bakker M, Quax P, Goudsmit J & Havenga M (2004), Novel replication-incompetent vector derived from adenovirus type 11 (Ad11) for vaccination and gene therapy: Low seroprevalence and non-cross-reactivity with Ad5.
- Hollestelle SCG, de Vries MR, van Keulen JK, Schoneveld AH, Vink A, Strijder CF, van Middelaar BJ, Pasterkamp G, Quax PHA & de Kleijn DPV (2004), Toll-like receptor 4 is involved in outward arterial remodeling, Circulation 109(3).
- van der Bas JMA, Quax PHA, van den Berg AC, Visser MJT, van der Linden E & van Bockel JH (2004), Ingrowth of aorta wall into stent grafts impregnated with basic fibroblast growth factor: A porcine in vivo study of blood vessel prosthesis healing, Journal of Vascular Surgery 39(4).
- Plaisier M, Kapiteijn K, Koolwijk P, Fijten C, Hanemaaijer R, Grimbergen JM, Mulder-Stapel A, Quax PHA, Helmerhorst FM & van Hinsbergh VWM (2004), Involvement of membrane-type matrix metalloproteinases (MT-MMPs) in capillary tube formation by human endometrial microvascular endothelial cells: Role of MT3-MMP, Journal of Clinical Endocrinology and Metabolism 89(11).
- Quax P, Pires N, van Vlijmen B, Havekes L & Jukema W (2004), Novel mouse model for rapid screening of anti-restenotic drugs using a drug fluting perivascular device, Atherosclerosis. Supplements 5(1).
- van Weel V, Voshol P, van Hinsbergh V, van Bockel H & Quax P (2004), Hampered collateral vessel development in hyperlipidaemic APOE3*Leiden transgenic mice, but not in mouse models of type I and II diabetes, Atherosclerosis. Supplements 5(1).
- Van Weel V, Toes RE, Sipkens J, Van Hinsbergh VW, Van Bockel JH & Quax P (2004), Arteriogenesis is hampered in the absence of CD4(+) T lymphocytes after CD4 depletion or in MHC class II-/- mice, Circulation 110(17): 71-71.
- Pires NMM, Van der Hoeven BL, Van Viijmen BJM, Quax PA, Havekes LM, Hennink WE & Jukema JW (2004), Novel mouse model for rapid screening of anti-restenotic drugs using a drug-eluting perivascular device, European Heart Journal 25: 519-519.
- Quax P, de Vries M, Vink A, Schepers A, Eefting D, Pires N, Jukema W, van Bockel H & de Kleijn D (2004), Toll-like receptor 4 is involved in the regulation of vascular remodeling, Atherosclerosis. Supplements 5(1): 1-1.
- Hauer AD, de Vos P, Peterse N, van Weel V, van Puijvelde GH, Quax PH, Berkel TJ & Kuiper J (2004), Vaccination against VEGF receptor 2 blocks initiation and progression of atherosclerosis, Circulation 110(17): 79-79.
- Bellu AR, Rotz MG, Bouis D, Mulder NH, Dam W, van Weel V, Koolwijk P, Quax PHA, Haisma HJ & Hosper GAP (2004), VEGF associated with TP to refine angiogenesis in gene therapy, Molecular Therapy 9: S58-S59.
- Eefting D, Schepers A, Grimbergen JM, de Vries MR, Miyazaki J, van Bockel JH & Quax P (2004), Once-only intramuscular delivery of Fc-fusion interleukin-10 plasmid by electroporation reduces neointima formation in hypercholesterolemic mice, Circulation 110(17): 140-140.
- Drynda A, Quax PHA, van der Laan W, Neumann M, Pap G, Andreas M, Drynda S, Kekow J, Neumann W, Gay S & Pap T (2004), Gene transfer of TIMP-3 facilitates apoptosis and reverses the anti-apoptotic effects of TNF-alpha in RA-SF., Arthritis and Rheumatism 50(9): S245-S245.
- Arkenbout EK, van Bragt M, Eldering E, van Bree C, Grimbergen JM, Quax PHA, Pannekoek H & de Vries CJM (2003), TR3 orphan receptor is expressed in vascular endothelial cells and mediates cell cycle arrest, Arteriosclerosis, Thrombosis, and Vascular Biology 23(9).
- Collen A, Hanemaaijer R, Lupu F, Quax PHA, van Lent N, Grimbergen J, Peters E, Koolwijk P & van Hinsbergh VWM (2003), Membrane-type matrix metalloproteinase-mediated angiogenesis in a fibrin-collagen matrix, Blood 101(5).
- van der Laan WH, Quax PHA, Seemayer CA, Huisman LGM, Pieterman EJ, Grimbergen JM, Verheijen JH, Breedveld FC, Gay RE, Gay S, Huizinga TWJ & Pap T (2003), Cartilage degradation and invasion by rheumatoid synovial fibroblasts is inhibited by gene transfer of TIMP-1 and TIMP-3, Gene Therapy 10(3).
- Vogels R, Zuijdgeest D, van Rijnsoever R, Hartkoorn E, Damen I, de Bethune MP, Kostense S, Penders G, Helmus N, Koudstaal W, Cecchini M, Wetterwald A, Sprangers M, Lemckert A, Ophorst O, Koel B, van Meerendonk M, Quax P, Panitti L, Grimbergen J, Bout A, Goudsmit J & Havenga M (2003), Replication-deficient human adenovirus type 35 vectors for gene transfer and vaccination: Efficient human cell infection and bypass of preexisting adenovirus immunity, Journal of Virology 77(15).
- Hollestelle SC, de Vries M, van Keulen KJ, Schoneveld AH, van Middelaar BJ, Pasterkamp G, Quax PH & de Kleijn DP (2003), Toll like receptor 4 is involved in outward arterial remodeling, Circulation 108(17): 23-23.
- Lamfers MLM, Bosscher L, Grimbergen JM, Hoebe EK, Vandertop WP, Dirven CMF, Gerritsen WR & Quax PHA (2003), Adenoviral gene transfer of the novel hybrid protein TIMP-1-ATF inhibits invasion of malignant glioma cells, Molecular Therapy 7(5): S354-S355.
- Lardenoye JHP, de Vries MR, Grimbergen JM, Havekes LM, Knaapen MWM, Kockx MM, van Hinsbergh VWM, van Bockel JH & Quax PHA (2002), Inhibition of accelerated atherosclerosis in vein grafts by placement of external stent in ApoE*3-Leiden transgenic mice, Arteriosclerosis, Thrombosis, and Vascular Biology 22(9).
- Lamfers MLM, Grimbergen JM, Aalders MC, Havenga MJ, de Vries MR, Huisman LGM, van Hinsbergh VWM & Quax PHA (2002), Gene transfer of the urokinase-type plasminogen activator receptor-targeted matrix metalloproteinase inhibitor TIMP-1.ATF suppresses neointima formation more efficiently than tissue inhibitor of metalloproteinase-1, Circulation Research 91(10).
- Lamfers MLM, Aalders MC, Grimbergen JM, de Vries MR, Kockx MM, van Hinsbergh VWM & Quax PHA (2002), Adenoviral delivery of a constitutively active retinoblastoma mutant inhibits neointima formation in a human explant model for vein graft disease, Vascular Pharmacology 39(6).
- Engelse MA, Lardenoye JHP, Neele JM, Grimbergen JM, de Vries MR, Lamfers MLM, Pannekoek H, Quax PHA & de Vries CJM (2002), Adenoviral activin A expression prevents intimal hyperplasia in human and murine blood vessels by maintaining the contractile smooth muscle cell phenotype, Circulation Research 90(10).
- Lardenoye JHP, de Vries MR, Lowik CWGM, Xu Q, Dhore CR, Cleutjens JPM, van Hinsbergh VWM, van Bockel JH & Quax PHA (2002), Accelerated atherosclerosis and calcification in vein grafts - A study in APOE*3 Leiden transgenic mice, Circulation Research 91(7).
- van der Bas JMA, Quax PHA, van den Berg AC, van Hinsbergh VWM & van Bockel JH (2002), Ingrowth of aorta vascular cells into basic fibroblast growth factor-impregnated vascular prosthesis material: A porcine and human in vitro study on blood vessel prosthesis healing, Journal of Vascular Surgery 36(6).
- Pap T., Drynda A., Seemayer C. A., Quax P. H. A., Verheijen J. H., Drynda S., Huizinga T. W. J., Michel B. A., Gay R. E., Gay S. & van der Laan W. H. (2002), Effects of TIMP-1 and TIMP-3 gene transfer on invasiveness, proliferation and apoptosis of rheumatoid arthritis (RA) synovial fibroblasts (RA-SF).
- Lardenoyel JHP, De Vries MR, van Hinsbergh VWM, Van Bockel JH & Quax PHA (2002), Effect of hypercholesterolemia on intimal hyperplasia in vein grafts in Apoe3*Leiden mice, Clinical and Experimental Pharmacology and Physiology 29(8): A92-A93.
- Havenga MJE, Lemckert AAC, Ophorst OJAE, van Meijer M, Germeraad WTV, Grimbergen J, van den Doel MA, Vogels R, van Deutekom J, Janson AAM, de Bruijn JD, Uytdehaag F, Quax PHA, Logtenberg T, Mehtali M & Bout A (2002), Exploiting the natural diversity in adenovirus tropism for therapy and prevention of disease, Journal of Virology 76(9).
- Lardenoye JHP, De Vries MR, van Hinsbergh VWM, Van Bockel JH & Quax PHA (2002), Rapid hypercholesterolemia-induced foam cell accumulation by placement of a perivascular cuff in Apoe*3leiden mice, Clinical and Experimental Pharmacology and Physiology 29(8): A91-A91.
- Tacken PJ, Delsing DJM, Gijbels MJJ, Quax PHA, Havekes LM, Hofker MH & van Dijk KW (2002), VLDL receptor deficiency enhances intimal thickening after vascular injury but does not affect atherosclerotic lesion area, Atherosclerosis 162(1).
- van Weel V, de Vries MR, van den Berg AC, Grimbergen JM, van Bockel JH & Quax PHA (2002), Mouse model of hindlimb ischemia to study gene therapy strategies for improvement of vasculature., Clinical and Experimental Pharmacology and Physiology 29(8): A95-A95.
- Vink A, van der Meer JJ, van Middelaar B, Quax PH, Borst C, Pasterkamp G & de Kleijn DP (2002), Activation of toll-like receptor 4 in adventitial cells by lipopolysaccharide induces neointima formation in a mouse model, Journal of the American College of Cardiology 39(5): 265A-265A.
- Vink A, Schoneveld AH, van der Meer JJ, van Middelaar BJ, Sluijter JPG, Smeets MB, Quax PHA, Lim SK, Borst C, Pasterkamp G & de Kleijn DPV (2002), In vivo evidence for a role of toll-like receptor 4 in the development of intimal lesions, Circulation 106(15): 1985-1990.
- Quax PHA, Lamfers MLM, Lardenoye JHP, Grimbergen JM, de Vries MR, Slomp J, de Ruiter MC, Kockx MM, Verheijen JH & van Hinsbergh VWM (2001), Adenoviral expression of a urokinase receptor-targeted protease inhibitor inhibits neointima formation in murine and human blood vessels, Circulation 103(4).
- Havenga MJE, Lemckert AAC, Grimbergen JM, Vogels R, Huisman LGM, Valerio D, Bout A & Quax PHA (2001), Improved adenovirus vectors for infection of cardiovascular tissues, Journal of Virology 75(7).
- Lardenoye JWH, De Vries M, Van Bockel H, Van Hinsbergh V & Quax P (2001), Inhibition of accelerated atherosclerosis in vein grafts by placement of external stent in ApoE*3 Leiden transgenic mice, Circulation 104(17): 713-713.
- Lamfers MLM, Lardenoye JHP, de Vries MR, Aalders MC, Engelse MA, Grimbergen JM, van Hinsbergh VWM & Quax PHA (2001), In vivo suppression of restenosis in balloon-injured rat carotid artery by adenovirus-mediated gene transfer of the cell surface-directed plasmin inhibitor ATF.BPTI, Gene Therapy 8(7).
- Brooks TD, Slomp J, Quax PHA, De Bart ACW, Spencer MT, Verheijen JH & Charlton PA (2001), Antibodies to PAI-1 alter the invasive and migratory properties of human tumour cells in vitro, Clinical and Experimental Metastasis 18(6): 445-453.
- van der Pluijm G, Sijmons B, Vloedgraven H, van der Bent C, Drijfhout JW, Verheijen J, Quax P, Karperien M, Papapoulos S & Lowik C (2001), Urokinase-receptor/integrin complexes are functionally involved in adhesion and progression of human breast cancer in vivo, American Journal of Pathology 159(3).
- Havenga MJE, van Dam B, Groot BS, Grimbergen JM, Valerio D, Bout A & Quax PHA (2001), Simultaneous detection of NOS-3 protein expression and nitric oxide production using a flow cytometer, Analytical Biochemistry 290(2).
- van der Laan W. H., Pap T., Quax P. H. A., TeKoppele J. M., Breedveld F. C., Gay S., Gay R. E., Verheijen J. H. & Huizinga T. W. J. (2001), Transfer of protease inhibitors to inhibit cartilage destruction.
- van der Laan W. H., Huisman L., Pieterman E., Quax P. H. A., TeKoppele J. M., Breedveld F. C., Verheijen J. H. & Huizinga T. W. J. (2001), Adenoviral gene transfer of tissue inhibitors of metalloproteinases (TIMPs) reduces the invasive behaviour of rheumatoid fibroblast-like synovicytes.
- van der Laan WH, Seemayer CA, Quax PHA, Verheijen JH, Huizinga TWJ, Breedveld FC, Michel BA, Gay RE, Gay S & Pap T (2001), Gene transfer of TIMP-1 and TIMP-3 inhibits proliferation of RA synovial fibroblasts and reduces cartilage invasion in the SCID mouse model of RA., Arthritis and Rheumatism 44(9): S294-S294.
- van Dam B, Schalkwijk CG, Grimbergen JM, Havenga MJE, Stehouwer CDA, Quax PHA & van Hinsbergh VWM (2001), Adenoviral eNOS transfer decreases TNF alpha-induced expression of VCAM-1 and attenuates the nuclear translocation of NF kappa B and IRF-1 in human endothelial cells, Arteriosclerosis, Thrombosis, and Vascular Biology 21(4): 673-673.
- Goedde MF, Grimbergen JM, Toet KH, Sitter T, Quax PH & Kooistra T (2001), Adenovirus-mediated transfer of the 39 kD receptor-associated protein increases fibrinolytic capacity, Kidney International 60(1): 117-125.
- Havenga MJE, Lemckert AAC, Grimbergen JM, Vogels R, Huisman LGM, Valerio D, Bout A & Quax PHA (2001), Improved adenovirus vectors for infection of cardiovascular tissues (vol 75, pg 3335, 2001), Journal of Virology 75(11): 5441-5441.
- Quax P, Lamfers M, Lardenoye JW, Grimbergen J, Devries M & Van Hinsbergh V (2001), Gene transfer of novel hybrid protein, TIMP-ATF, a cell-surface directed MMP inhibitor, suppresses neointima formation more efficiently than TIMP-1, Circulation 104(17): 259-259.
- Lardenoye JHP, Delsing DJM, de Vries MR, Deckers MML, Princen HMG, Havekes LM, van Hinsbergh VWM, van Bockel JH & Quax PHA (2000), Accelerated atherosclerosis by placement of a perivascular cuff and a cholesterol-rich diet in ApoE*3Leiden transgenic mice.
- Van der Laan WH, Pap T, Ronday HK, Grimbergen JM, Huisman LGM, TeKoppele JM, Breedveld DC, Gay RE, Gay S, Huizinga TWJ, Verheijen JH & Quax PHA (2000), Cartilage degradation and invasion by rheumatoid synovial fibroblasts is inhibited by gene transfer of a cell surface-targeted plasmin inhibitor, Arthritis and Rheumatism 43(8): 1710-1718.
- van der Pluijm G, Sijmons B, Que I, Deckers M, Lardenoye J, Quax P, Papapoulos S & Lowik C (2000), Angiogenesis and vasculogenic mimicry in breast cancer metastasis: Effect of plasmin inhibition by a new hybrid protein., Journal of Bone and Mineral Research 15: S255S255.
- Engelse, M.A.; Lardenoye, J.H.P.; Lamfers, M.L.M.; Neele, J.M.; Vries, M.R.; Grimbergen, J.M.; Pannekoek, H.; Vries, C.J. & Quax, P.H. (2000), Adenovirus mediated overexpression of activin, a TGF beta-like factor, inhibits neointima formation in cultured human saphenous veins in vitro and in cuff-induced murine vascular hyperplasia in vivo., Circulation 102(18): 146-146.
- Quax, P.H.; Lamfers, M.L.M.; Lardenoye, J.H.P.; Grimbergen, J.M.; Vries, M.R. & Hinsbergh, V.W.M. (2000), Adenovirus mediated local overexpression of ATF.BPTI, a cell surface directed plasmin inhibitor, reduces neointima formation in balloon injured rat carotid arteries in vivo., Circulation 102(18): 146-146.
- van der Laan WH, Goossens PH, Pieterman EJ, Quax PHA, TeKoppele JM, Breedveld FC, Huizinga TWJ & Verheijen JH (2000), More profound inhibitory effect of TIMP-3 gene transfer than TIMP-1 gene transfer on synovial fibroblast invasion., Arthritis and Rheumatism 43(9): S170-S170.
- Lamfers MLM, Wijnberg MJ, Grimbergen JM, Huisman LGM, Aalders MC, Cohen FNB, Verheijen JH, van Hinsbergh VWM & Quax PHA (2000), Adenoviral gene transfer of a u-PA receptor-binding plasmin inhibitor and green fluorescent protein: Inhibition of migration and visualization of expression, Thrombosis and Haemostasis 84(3): 460-467.
- van Hinsbergh VWM, Koolwijk P, Collen A, Kroon M, Hanemaaijer R, Verheijen JH & Quax PHA (1999), Endothelial and smooth muscle plasminogen activators in fibrinolysis, cell migration and repair-associated angiogenesis, Nato Asi Series a Life Sciences 308: 157-178.
- van der Laan WH, Ronday HK, Grimbergen JM, Huisman IGM, Breedveld FC, Koppele JMT, Huizinga TWJ, Quax PHA & Verheijen JH (1999), Degradation of a cartilage-like matrix by rheumatoid synovial fibroblasts is inhibited by gene transfer with a cell surface-targeted plasmin inhibitor., Arthritis and Rheumatism 42(9): S163-S163.
- Sitter T, Toet K, Quax P & Kooistra T (1999), Fibrinolytic activity of human mesothelial cells is counteracted by rapid uptake of tissue-type plasminogen activator, Kidney International 55(1): 120-129.
- Quax PHA, Grimbergen JM, Lansink M, Bakker AHF, Blatter MC, Belin D, van Hinsbergh VWM & Verheijen JH (1998), Binding of human urokinase-type plasminogen activator to its receptor - Residues involved in species specificity and binding, Arteriosclerosis, Thrombosis, and Vascular Biology 18(5): 693-701.
- van Hinsbergh VWM, Koolwijk P, Ponfoort E, Hanemaaijer R, Emeis JJ, Kooistra T & Quax PHA (1998), Role of endothelial plasminogen activators in fibrinolysis and repair-associated angiogenesis - Two sides of a coin, Nato Asi Series a Life Sciences 294: 77-97.
- Koopman JL, Slomp J, de Bart ACW, Quax PHA & Verheijen JH (1998), Mitogenic effects of urokinase on melanoma cells are independent of high affinity blinding to the urokinase receptor, Journal of Biological Chemistry 273(50): 33267-33272.
- van der Laan WH, Goosens PH, Grimbergen JM, Breedveld FC, Verheijen JH, Huizinga TWJ & Quax PHA (1998), Genetherapy mediated inhibition of pericellular cartilage degradation by rheumatoid fibroblast-like synoviocytes, Arthritis and Rheumatism 41(9): S161-S161.
- Ronday HK, Smits HH, Quax PHA, vanderPluijm G, Lowik CWGM, Breedveld FC & Verheijen JH (1997), Bone matrix degradation by the plasminogen activation system. Possible mechanism of bone destruction in arthritis, British journal of rheumatology 36(1): 9-15.
- DanenVanOorschot AAAM, Fischer DF, Grimbergen JM, Klein B, Zhuang SM, Falkenburg JHF, Backendorf C, Quax PHA, VanderEb AJ & Noteborn MHM (1997), Apoptin induces apoptosis in human transformed and malignant cells but not in normal cells, Proceedings of the National Academy of Sciences 94(11): 5843-5847.
- Wijnberg MJ, Quax PHA, Nieuwenbroek NME & Verheijen JH (1997), The migration of human smooth muscle cells in vitro is mediated by plasminogen activation and can be inhibited by alpha(2)-macroglobulin receptor associated protein, Thrombosis and Haemostasis 78(2): 880-886.
- Quax PHA, deBart ACW, Schalken JA & Verheijen JH (1997), Plasminogen activator and matrix metalloproteinase production and extracellular matrix degradation by rat prostate cancer cells in vitro: Correlation with metastatic behavior in vivo, Prostate 32(3): 196-204.
- Quax PHA, Lamfers ML, Grimbergen JG, Verheijen JH & vanHinsbergh VW (1997), Inhibition of neointima formation in cultured human saphenous vein segments by an adenovirus expressing an urokinase receptor binding plasmin inhibitor, Circulation 96(8): 3741-3741.
- Quax PHA, Lamfers MLM, Grimbergen JM, Teeling J, Hoeben RC, Amerongen GPV & vanHinsbergh VWM (1996), Effects of infection with recombinant adenovirus on human vascular endothelial and smooth muscle cells, Fibrinolysis 10: 71-74.
- Wijnberg MJ, Nieuwenbroek NME, Slomp J, Quax PHA & Verheijen JH (1996), Urokinase and tissue-type plasminogen activator stimulate human vascular smooth muscle cell migration, Fibrinolysis 10: 75-78.
- BOXMAN ILA, QUAX PHA, LOWIK CWGM, PAPAPOULOS SE, VERHEIJEN J & PONEC M (1995), DIFFERENTIAL REGULATION OF PLASMINOGEN ACTIVATION IN NORMAL KERATINOCYTES AND SCC-4 CELLS BY FIBROBLASTS, Journal of Investigative Dermatology 104(3): 374-378.
- DEVRIES TJ, MOOY CM, VANBALKEN MR, LUYTEN GPM, QUAX PHA, VERSPAGET HW, WEIDLE UH, RUITER DJ & VANMUIJEN GNP (1995), COMPONENTS OF THE PLASMINOGEN ACTIVATION SYSTEM IN UVEAL MELANOMA - A CLINICOPATHOLOGICAL STUDY, Journal of Pathology 175(1): 59-67.
- VANHINSBERGH VWM, QUAX PHA, KOOLWIJK P & VERHEIJEN JH (1995), ROLE OF PLASMINOGEN ACTIVATORS AND THEIR INHIBITOR PAI-1 IN PERICELLULAR PROTEOLYSIS OF SMOOTH MUSCLE CELLS AND ENDOTHELIAL CELLS, International Congress Series 1066: 694-696.
- DEBART ACW, QUAX PHA, LOWIK CWGM & VERHEIJEN JH (1995), REGULATION OF PLASMINOGEN ACTIVATION, MATRIX METALLOPROTEINASES AND UROKINASE-TYPE PLASMINOGEN ACTIVATOR-MEDIATED EXTRACELLULAR-MATRIX DEGRADATION IN HUMAN OSTEOSARCOMA CELL-LINE MG63 BY INTERLEUKIN-1-ALPHA, Journal of Bone and Mineral Research 10(9): 1374-1384.
- RONDAY HK, SMITS HH, QUAX PHA, VANDERPLUIJM G, LOWIK CWGM, BREEDVELD FC & VERHEIJEN JH (1995), UROKINASE MEDIATED, PLASMIN DEPENDENT DEGRADATION OF BONE-LIKE MATRIX, Arthritis and Rheumatism 38(9): 1237-1237.
- GANESH S, SIER CFM, HEERDING MM, VLOEDGRAVEN HJM, QUAX PHA, VERHEIJEN JH, GRIFFIOEN G, LAMERS CBHW & VERSPAGET HW (1995), ACTIVE INVOLVEMENT OF THE UROKINASE-RECEPTOR IN COLONIC-CANCER.
- QUAX PHA, BOXMAN LA, VANKESTEREN CAM, VERHEIJEN JH & PONEC M (1994), PLASMINOGEN ACTIVATORS ARE INVOLVED IN KERATINOCYTE AND FIBROBLAST MIGRATION IN WOUNDED CULTURES IN-VITRO, Fibrinolysis 8(4): 221-228.
- DEVRIES TJ, QUAX PHA, DENIJN M, VERHEIJEN JH, VERSPAGET HW, WEIDLE UH, RUITER DJ, VANMUIJEN GNP & VERRIJP KN (1994), PLASMINOGEN ACTIVATORS, THEIR INHIBITORS, AND UROKINASE RECEPTOR EMERGE IN LATE STAGES OF MELANOCYTIC TUMOR PROGRESSION, American Journal of Pathology 144(1): 70-81.
- PADRO T, QUAX PHA, VANDENHOOGEN CM, ROHOLL P, VERHEIJEN JH & EMEIS JJ (1994), TISSUE-TYPE PLASMINOGEN-ACTIVATOR AND ITS INHIBITOR IN RAT AORTA - EFFECT OF ENDOTOXIN, Arteriosclerosis and thrombosis : a journal of vascular biology / American Heart Association 14(9): 1459-1465.
- PEVERALI FA, MANDRIOTA SJ, CIANA P, MARELLI R, QUAX P, RIFKIN DB, DELLAVALLE G & MIGNATTI P (1994), TUMOR-CELLS SECRETE AN ANGIOGENIC FACTOR THAT STIMULATES BASIC FIBROBLAST GROWTH-FACTOR AND UROKINASE EXPRESSION IN VASCULAR ENDOTHELIAL-CELLS, Journal of Cellular Physiology 161(1): 1-14.
- SIER CFM, VLOEDGRAVEN HJM, GANESH S, GRIFFIOEN G, QUAX PHA, VERHEIJEN JH, DOOIJEWAARD G, WELVAART K, VANDEVELDE CJH, LAMERS CBHW & VERSPAGET HW (1994), INACTIVE UROKINASE AND INCREASED LEVELS OF ITS INHIBITOR TYPE-1 IN COLORECTAL-CANCER LIVER METASTASIS.
- WEIDLE UH, WOLLISCH E, RONNE E, PLOUG M, BEHRENDT N, DEVRIES TJ, QUAX PH, VERHEIJEN JH, VANMUIJEN GNP, RUITER DJ, HOYERHANSEN G & DANO K (1994), STUDIES ON FUNCTIONAL AND STRUCTURAL ROLE OF UROKINASE RECEPTOR AND OTHER COMPONENTS OF THE PLASMINOGEN ACTIVATION SYSTEM IN MALIGNANCY, Annales de Biologie Clinique 52(11): 775-782.
- VANKESTEREN T, QUAX P, BOXMAN I, KEMPENAAR J, VERHEIJEN J & PONEC M (1993), PLASMINOGEN ACTIVATION IS INVOLVED IN KERATINOCYTE AND FIBROBLAST MIGRATION, Journal of Investigative Dermatology 100(4): 438-438.
- SIER CFM, QUAX PHA, VLOEDGRAVEN HJM, VERHEIJEN JH, GRIFFIOEN G, GANESH S, LAMERS CBHW & VERSPAGET HW (1993), INCREASED UROKINASE RECEPTOR LEVELS IN HUMAN GASTROINTESTINAL NEOPLASIA AND RELATED LIVER METASTASES, Invasion and Metastasis 13(6): 277-288.
- SIER CFM, VLOEDGRAVEN HJM, QUAX PHA, VERHEIJEN JH, GRIFFIOEN G, LAMERS CBHW & VERSPAGET HW (1993), HIGH-LEVELS OF UROKINASE-RECEPTOR IN HUMAN COLORECTAL-CARCINOMA AND LIVER METASTASIS.
- SPERTI G, VANLEEUWEN RTJ, QUAX PHA, MASERI A & KLUFT C (1992), CULTURED RAT AORTIC VASCULAR SMOOTH-MUSCLE CELLS DIGEST NATURALLY PRODUCED EXTRACELLULAR-MATRIX - INVOLVEMENT OF PLASMINOGEN-DEPENDENT AND PLASMINOGEN-INDEPENDENT PATHWAYS, Circulation Research 71(2): 385-392.
- QUAX PHA, FRISDAL E, PEDERSEN N, BONAVAUD S, THIBERT P, MARTELLY I, VERHEIJEN JH, BLASI F & BARLOVATZMEIMON G (1992), MODULATION OF ACTIVITIES AND RNA LEVEL OF THE COMPONENTS OF THE PLASMINOGEN ACTIVATION SYSTEM DURING FUSION OF HUMAN MYOGENIC SATELLITE CELLS-INVITRO, Developmental Biology 151(1): 166-175.
- QUAX PHA, VANMUIJEN GNP, PEDERSEN N, DEBART ACW, SCHRAUWEN Y, BARLOVATZMEIMON G, BLASI F & VERHEIJEN JH (1992), THE PLASMINOGEN-ACTIVATOR SYSTEM IN EXTRACELLULAR-MATRIX DEGRADATION, Fibrinolysis 6: 41-44.
- BOXMAN I, QUAX P, VANLEEUWEN F, VERHEIJEN J, LOWIK C & PONEC M (1992), FIBROBLAST-INDUCED MODULATION OF THE UROKINASE-PLASMINOGEN ACTIVATOR-RECEPTOR (U-PA-R) IN SQUAMOUS CARCINOMA-CELLS (SCC-4) AND NORMAL HUMAN KERATINOCYTES, Journal of Investigative Dermatology 98(4): 504-504.
- HENNIS BC, DEMAAT MPM, QUAX PHA, LECLERCQ EJ, KUIPER J & KLUFT C (1991), EVALUATION OF SITES OF SYNTHESIS OF THE HISTIDINE-RICH GLYCOPROTEIN, Thrombosis and Haemostasis 65(6): 884-884.
- QUAX PHA, PEDERSEN N, MASUCCI MT, WEENINGVERHOEFF EJD, DANO K, VERHEIJEN JH & BLASI IF (1991), COMPLEMENTATION BETWEEN UROKINASE-PRODUCING AND RECEPTOR-PRODUCING CELLS IN EXTRACELLULAR-MATRIX DEGRADATION, Cell regulation 2(10): 793-803.
- QUAX PHA, FRISAL E, PEDERSEN N, BONAVAUD S, VERHEIJEN H, BLASI F & BARLOVATZMEIMON G (1991), CELL-SURFACE PLASMINOGEN ACTIVATION IS REQUIRED FOR DIFFERENTIATION OF HUMAN ADULT MYOGENIC CELLS-INVITRO, Thrombosis and Haemostasis 65(6): 665-665.
- WEENINGVERHOEFF EJD, BAKKER AHF, QUAX PHA & VERHEIJEN JH (1991), LYSINE BINDING AND FIBRIN-BINDING OF T-PA - AS STUDIED BY LOCALIZED MUTAGENESIS, Thrombosis and Haemostasis 65(6): 1307-1307.
- QUAX PHA, VANMUIJEN GNP, WEENINGVERHOEFF EJD, LUND LR, DANO K, RUITER DJ & VERHEIJEN JH (1991), METASTATIC BEHAVIOR OF HUMAN-MELANOMA CELL-LINES IN NUDE-MICE CORRELATES WITH UROKINASE-TYPE PLASMINOGEN-ACTIVATOR, ITS TYPE-1 INHIBITOR, AND UROKINASE-MEDIATED MATRIX DEGRADATION, Journal of Cell Biology 115(1): 191-199.
- QUAX PHA, PADRO T, EMEIS JJ, VANDENHOOGEN RM & VERHEIJEN JH (1991), TISSUE-TYPE PLASMINOGEN-ACTIVATOR AND PLASMINOGEN-ACTIVATOR INHIBITOR TYPE-1 IN NORMAL AND ENDOTOXIN-TREATED RAT AORTA, Thrombosis and Haemostasis 65(6): 834-834.
- QUAX PHA, PEDERSEN N, WEENINGVERHOEFF EJD, MASUCCI MT, VERHEIJEN JH & BLASI F (1991), PLASMIN MEDIATED EXTRACELLULAR MATRIXDEGRADATION - THE ROLE OF UROKINASE PLASMINOGEN-ACTIVATOR AND THE UROKINASE RECEPTOR, Thrombosis and Haemostasis 65(6): 723-723.
- SIER CFM, VERSPAGET HW, GRIFFIOEN G, VERHEIJEN JH, QUAX PHA, DOOIJEWAARD G, DEBRUIN PAF & LAMERS CBHW (1991), IMBALANCE OF PLASMINOGEN ACTIVATORS AND THEIR INHIBITORS IN HUMAN COLORECTAL NEOPLASIA - IMPLICATION OF UROKINASE IN COLORECTAL CARCINOGENESIS.
- QUAX PHA, VANDENHOOGEN CM, VERHEIJEN JH, PADRO T, ZEHEB R, GELEHRTER TD, VANBERKEL TJC, KUIPER J & EMEIS JJ (1990), ENDOTOXIN INDUCTION OF PLASMINOGEN-ACTIVATOR AND PLASMINOGEN-ACTIVATOR INHIBITOR TYPE-1 MESSENGER-RNA IN RAT-TISSUES INVIVO, Journal of Biological Chemistry 265(26): 15560-15563.
- QUAX PHA, VANLEEUWEN RTJ, VERSPAGET HW & VERHEIJEN JH (1990), PROTEIN AND MESSENGER-RNA LEVELS OF PLASMINOGEN ACTIVATORS AND INHIBITORS ANALYZED IN 22 HUMAN TUMOR-CELL LINES, Cancer Research 50(5): 1488-1494.
- SPERTI G, QUAX P, VANLEEUWEN R & KLUFT C (1990), PAI-1 AND T-PA MESSENGER-RNAS ARE EXPRESSED BY VASCULAR SMOOTH-MUSCLE INVIVO, Circulation 82(4): 573-573.
- WEENINGVERHOEFF EJD, QUAX PHA, VANLEEUWEN RTJ, REHBERG EF, MAROTTI KR & VERHEIJEN JH (1990), INVOLVEMENT OF ASPARTIC AND GLUTAMIC RESIDUES IN KRINGLE-2 OF TISSUE-TYPE PLASMINOGEN-ACTIVATOR IN LYSINE BINDING, FIBRIN BINDING AND STIMULATION OF ACTIVITY AS REVEALED BY CHEMICAL MODIFICATION AND OLIGONUCLEOTIDE-DIRECTED MUTAGENESIS, Protein Engineering -Oxford- 4(2): 191-198.
- SPERTI G, QUAX P, ANDREOTTI F, REGAN T, ANTONIW J, MASERI A & KLUFT C (1989), SERUM AND VASOCONSTRICTORS INCREASE PAI-1 PRODUCTION AND MESSENGER-RNA IN CULTURED RAT VASCULAR SMOOTH-MUSCLE CELLS, Clinical research 37(2): A298-A298.
- Lid van Editorial Board als associated Editor
- Lid van de Scientific Advisory Board