Matthias Barz
Hoogleraar Biotherapeutics delivery
- Naam
- Prof.dr. M. Barz
- Telefoon
- +31 71 527 2727
- m.barz@lacdr.leidenuniv.nl
- ORCID iD
- 0000-0002-1749-9034
Meer informatie is beschikbaar op de Engelse profielpagina.
Nieuws
-
Hoe medicijnen beter werken als ze verpakt zijn in nanodeeltjes -
Samenwerking van instituten tegen TBC in het Leidsch Dagblad -
Medicijnen met minder bijwerkingen: Leidse onderzoeksgroep werkt eraan met Spaans bedrijf -
Leidse onderzoekers slaan handen ineen tegen tuberculose -
Dies natalis in teken van vernieuwen en verbinden -
Nieuwe hoogleraar Biotherapeutics delivery bij LACDR
Oud-promovendi
Hoogleraar Biotherapeutics delivery
- Wiskunde en Natuurwetenschappen
- Leiden Academic Centre for Drug Research
- LACDR/Drug Delivery Technology
- Simic L., Miravet Martí R., Duro-Castaño A., Nebot V.J. & Barz M. (2024), Utility of triethyloxonium tetrafluoroborate for chloride removal during sarcosine N-carboxyanhydride synthesis: improving NCA purity, Chemistry: a European Journal : e202304375.
- Shalgunov V., Broek S.L. van den, Andersen I.V., Raval N.R., Schäfer G., Barz M., Herth M.M. & Battisti U.M. (2024), Evaluation of F-537-Tetrazine in a model for brain pretargeting imaging: comparison to N-(3-[18F] fluoro-5-(1,2,4,5-tetrazin-3-yl)benzyl)propan-1-amine, Nuclear Medicine and Biology 128-129: 108877.
- Horvat N.K., Chocarro S., Marques O., Bauer T.A., Qiu R., Diaz-Jimenez A., Helm B., Chen Y., Sawall S., Sparla R., Su L., Klingmüller U., Barz M., Hentze M.W., Sotillo R. & Muckenthaler M.U. (2024), Superparamagnetic iron oxide Nanoparticles reprogram the tumor microenvironment and reduce lung cancer regrowth after crizotinib treatment, ACS Nano 18(17): 11025-11041.
- Bi D., Hal A. van, Aschmann D., Shen M., Zhang H., Su L., Arias Alpizar G., Kros A., Barz M. & Bussmann J. (2024), Deconvolving passive and active targeting of liposomes bearing LDL receptor binding peptides using the zebrafish embryo model, Small : 2310781.
- Schwiertz D., Heck A., Muhl C., Su L. & Barzm M. (2024), Design of cross-linkable polypept(o)ide-based AB3 miktoarm star polymers through advances in PeptoMiktoStar synthesis, European Polymer Journal 210: 112989 (112989).
- Breder-Bonk C., Docter D., Barz M., Strieth S., Knauer S.K., Gül D. & Stauber R.H. (2023), The apoptosis inhibitor protein survivin is a critical cytoprotective resistor against silica-based nanotoxicity, Nanomaterials 13(18): 2546.
- Chen X.B., Yang H., Song X., Liang H., Wei Y., Lu J., Barz M., Jin R.R. & Nie Y. (2023), Integrated and dual-responsive lipopeptide nanovector with parallel effect to tumor and micro-environment regulation by efficient gene and drug co-delivery, Chinese Chemical Letters 34(5): 107753.
- Dal N.K., Schäfer G., Thompson A.M., Schmitt S., Redinger N., Alonso-Rodriguez N., Johann K., Ojong J., Wohlmann J., Best A., Koynov K., Zentel R., Schaible U.E., Griffiths G., Barz M. & Fenaroli F. (2023), Π-Π interactions stabilize PeptoMicelle-based formulations of Pretomanid derivatives leading to promising therapy against tuberculosis in zebrafish and mouse models, Journal of Controlled Release 354: 851-868.
- Bi D., Unthan D.M., Hu L., Bussmann J., Remaut K., Barz M. & Zhang H. (2023), Polysarcosine-based lipid formulations for intracranial delivery of mRNA, Journal of Controlled Release 356: 1-13.
- Shalgunov V., Lopes van den Broek S., Vang Andersen I., García Vázquez R., Raval N.R., Palner M., Mori Y., Schäfer G., Herrmann B., Mikula H., Beschorner N., Nedergaard M., Syvänen S., Barz M., Moos Knudsen G., Battisti U.M. & Herth M.M. (2023), Pretargeted imaging beyond the blood-brain barrier, RSC Medicinal Chemistry 14(3): 444-453.
- Wilhelmy C., Keil I.S., Uebbing L., Schroer M.A., Franke D., Nawroth T., Barz M., Sahin U., Haas H., Diken M. & Langguth P. (2023), Polysarcosine-functionalized mRNA lipid nanoparticles tailored for immunotherapy, Pharmaceutics 15(8): 2068.
- Bauer T.A., Alberg I., Zengerling L.A., Besenius P., Koynov K., Slütter B.A., Zentel R., Que I., Zhang H. & Barz M. (2023), Tuning the cross-linking density and cross-linker in core cross-linked polymeric micelles and its effects on the particle stability in human blood plasma and mice, Biomacromolecules 24(8): 3545-3556.
- Bauer T.A. Schramm J., Fenaroli F., Siemer S., Seidl C.I., Rosenauer C., Bleul R., Stauber R., Koynov K., Maskos M. & Barz M. (2023), Complex structures made simple: continuous flow production of core cross-linked polymeric micelles for paclitaxel pro-drug-delivery, Advanced Materials 35(21): 2210704.
- Capelôa L., Schwiertz D. & Barz M. (2023), Facile synthesis of AA'B- and ABC-type polypept(o)ide miktoarm star polymers utilizing polysarcosine end group functionalization for core introduction, European Polymer Journal 187: 111896.
- Capelôa L., Yazdi M., Zhang H., Chen X., Nie Y., Wagner E., Lächelt U. & Barz M. (2022), Cross-linkable polyion complex micelles from polypept(o)ide-based ABC-triblock copolymers for siRNA delivery, Macromolecular Rapid Communications 43(12): 2100698.
- Schmitt S., Nuhn L., Barz M., Butt H.J. & Koynov K. (2022), Shining light on polymeric drug nanocarriers with fluorescence correlation spectroscopy, Macromolecular Rapid Communications 43(12): 2100892.
- Shahneh F., Johann K., Bohn T., Klein M., Bopp T., Barz M. & Becker C. (2022), Suppression of cAMP formation by inhibitor-loaded polypept(o) ide micelles inhibits melanoma growth by preserving an inflammatory myeloid cell phenotype, Experimental Dermatology 31(2): E48-E48.
- Barz M., Nuhn L., Hörpel G. & Zentel R. (2022), From self-organization to tumor-immune therapy: how things started and how they evolved, Macromolecular Rapid Communications 43(12): 2100829.
- Dal N.K., Speth M., Johann K., Barz M., Beauvineau C., Wohlmann J., Fenaroli F., Gicquel B., Griffiths G. & Alonso-Rodriguez N. (2022), The zebrafish embryo as an in vivo model for screening nanoparticle-formulated lipophilic anti-tuberculosis compounds, Disease Models & Mechanisms 15(1): dmm049147.
- Barz M., Nuhn L. & Theato P. (2022), A tribute to Rudolf Zentel and his lifetime research achievements, Macromolecular Rapid Communications 43(12): 2200311.
- Shalgunov V., Engudar G., Bohrmann L., Wharton L., Maskell K., Johann K., Barz M., Schaffer P., Herth M.M. & Radchenko V. (2022), Radiolabeling of a polypeptide polymer for intratumoral delivery of alpha-particle emitter, 225Ac, and beta-particle emitter, 177Lu, Nuclear Medicine and Biology 104-105: 11-21.
- García-Vázquez R., Battisti U.M., Shalgunov V., Schäfer G., Barz M. & Herth M.M. (2022), [11C]Carboxylated tetrazines for facile labeling of trans-cyclooctene-functionalized PeptoBrushes, Macromolecular Rapid Communications 43(12): 2100655.
- Bauer T.A., Horvat N.K., Marques O., Chocarro S., Mertens C., Colucci S., Schmitt S., Carrella L.M., Morsbach S., Koynov K., Fenaroli F., Blümler P., Jung M., Sotillo R., Hentze M.W., Muckenthaler M.U. & Barz M. (2021), Core cross‐linked polymeric micelles for specific iron delivery: inducing sterile inflammation in macrophages, Advanced Healthcare Materials 10(19): 2100385.
- Sun Z., Qiao D., Shi Y., Barz M., Liu L. & Chen Y. (2021), Precision wormlike nanoadjuvant governs potency of vaccination, Nano Letters 21(17): 7236-7243.
- Johann K., Bohn T., Shahneh F., Luther N., Birke A., Jaurich H., Helm M., Klein M., Raker V.K., Bopp T., Barz M. & Becker C. (2021), Therapeutic melanoma inhibition by local micelle-mediated cyclic nucleotide repression, Nature Communications 12(1): 5981.
- Bauer T. A., Imschweiler J., Muhl C., Weber B. & Barz M. (2021), Secondary structure-driven self-assembly of thiol-reactive polypept(o)ides, Biomacromolecules 22(5): 2171-2180.
- Siemer S., Bauer T.A., Scholz P., Breder C., Fenaroli F., Harms G., Dietrich D., Dietrich J., Rosenauer C., Barz M., Becker S., Strieth S., Reinhardt C., Fauth T., Hagemann J. & Stauber R.H. (2021), Targeting cancer chemotherapy resistance by precision medicine-driven nanoparticle-formulated cisplatin, ACS Nano 15(11): 18541–18556.
- Bauer T.A., Muhl C., Schollmeyer D. & Barz M. (2021), Racemic S-(ethylsulfonyl)-dl-cysteine N-Carboxyanhydrides improve chain lengths and monomer conversion for beta-sheet-controlled ring-opening polymerization, Macromolecular Rapid Communications 42(8): 2000470.
- Chen X., Jin R., Jiang Q., Bi Q., He T., Song X., Barz M., Ai H., Shuai X. & Nie Y. (2021), Delivery of siHIF-1α to reconstruct tumor normoxic microenvironment for effective chemotherapeutic and photodynamic anticancer treatments, Small 17(25): 2100609.
- Bauer T.A., Eckrich J., Wiesmann N., Kuczelinis F., Sun W., Zeng X., Weber B., Wu S., Bings N.H., Strieth S. & Barz M. (2021), Photocleavable core cross-linked polymeric micelles of polypept(o)ides and ruthenium(II) complexes, Journal of Materials Chemistry B 9(39): 8211-8223.
- Kappel C., Seidl C., Medina-Montano C., Schinnerer M., Alberg I., Leps C., Sohl J., Hartmann A.K., Fichter M., Kuske M., Schunke J., Kuhn G., Tubbe I., Paßlick D., Hobernik D., Bent R., Haas K., Montermann E., Walzer K., Diken M., Schmidt M., Zentel R., Nuhn L., Schild H., Tenzer S., Mailänder V., Barz M., Bros M. & Grabbe S. (2021), Density of conjugated antibody determines the extent of Fc receptor dependent capture of nanoparticles by liver sinusoidal endothelial cells, ACS Nano 15(9): 15191-15209.
- Holm R., Schwiertz D.T., Weber B., Schultze J., Kuhn J., Koynov K., Lächelt. U. & Barz M. (2020), Multifunctional Cationic PeptoStars as siRNA Carrier: Influence of Architecture and Histidine Modification on Knockdown Potential, Macromolecular Bioscience 20(1): 1900152.
- Nogueira S.S., Schlegel A., Maxeiner K., Weber B., Barz M., Schroer M.A., Blanchet C.E., Svergun D.I., Ramishetti S., Peer D., Langguth P., Sahin U. & Haas H. (2020), Polysarcosine-functionalized lipid nanoparticles for therapeutic mRNA delivery, ACS Applied Nano Materials 3(11): 10634-10645.
- Liang H., Bi Q.J., Hu A., Chen X.B., Jin R.R., Song X., Ke B.W., Barz M. & Nie Y. (2020), A nitroreductase and glutathione responsive nanoplatform for integration of gene delivery and near-infrared fluorescence imaging, Chemical Communications 56(51): 6949-6952.
- Liang H., Chen X.B., Jin R.R., Ke B.W., Barz M., Ai H. & Nie Y. (2020), Integration of indocyanine green analogs as near-infrared fluorescent carrier for precise imaging-guided gene delivery, Small 16(10): 1906538.
- Alberg I., Kramer S., Schinnerer M., Hu Q.Z., Seidl C., Leps C., Drude N., Mockel D., Rijcken C., Lammers T., Diken M., Maskos M., Morsbach S., Landfester K., Tenzer S., Barz M. & Zentel R. (2020), Polymeric nanoparticles with neglectable protein corona, Small 16(18): e1907574.
- Chen C.J., Wunderlich K., Mukherji D., Koynov K., Heck A.J., Raabe M., Barz M., Fytas G., Kremer K., Ng D.Y.W. & Weil T. (2020), Precision anisotropic brush polymers by sequence controlled chemistry, Journal of the American Chemical Society 142(3): 1332-1340.
- Darguzyte M., Holm R., Baier J., Drude N., Schultze J., Koynov K., Schwiertz D.T., Dadfar S.M., Lammers T., Barz M. & Kiessling F. (2020), Influence of riboflavin targeting on tumor accumulation and internalization of peptostar based drug delivery systems, Bioconjugate Chemistry 31(12): 2691-2696.
- Dal N.J.K., Kocere A., Wohlmann J., Herck S. van, Bauer T.A., Resseguier J., Bagherifam S., Hyldmo H., Barz M., Geest B.G. de & Fenaroli F. (2020), Zebrafish embryos allow prediction of nanoparticle circulation times in mice and facilitate quantification of nanoparticle-cell interactions, Small 16(5): 1906719.
- Steen E.J.L., Jorgensen J.T., Johann K., Norregaard K., Sohr B., Svatunek D., Birke A., Shalgunov V., Edem P.E., Rossin R., Seidl C., Schmid F., Robillard M.S., Kristensen J.L., Mikula H., Barz M., Kjaer A. & Herth M.M. (2020), Trans-cyclooctene-functionalized peptobrushes with improved reaction kinetics of the tetrazine ligation for pretargeted nuclear imaging, ACS Nano 14(1): 568-584.
- Johann K., Svatunek D., Seidl C.I., Rizzelli S., Bauer T.A., Braun L., Koynov K., Mikula H. & Barz M. (2020), Tetrazine- and trans-cyclooctene-functionatised potypept(o)ides for fast bioorthogonal tetrazine ligation, Polymer Chemistry 11(27): 4396-4407.
- Bleher S., Buck J., Muhl C., Sieber S., Barnert S., Witzigmann D., Huwyler J., Barz M. & Suss R. (2019), Poly(sarcosine) surface modification imparts stealth-like properties to liposomes, Small 15(50): 1904716.
- Sun Q.X., Barz M., Geest B.G. de, Diken M., Hennink W.E., Kiessling F., Lammers T. & Shi Y. (2019), Nanomedicine and macroscale materials in immuno-oncology, Chemical Society Reviews 48(1): 351-381.
- Alkilany A.M., Zhu L., Weller H., Mews A., Parak W.J., Barz M. & Feliu N. (2019), Ligand density on nanoparticles: A parameter with critical impact on nanomedicine, Advanced Drug Delivery Reviews 143: 22-36.
- Holm R., Douverne M., Weber B., Bauer T., Best A., Ahlers P., Koynov K., Besenius P. & Barz M. (2019), Impact of Branching on the Solution Behavior and Serum Stability of Starlike Block Copolymers, Biomacromolecules 20(1): 375-388.
- Steinborn B., Hirschle P., Hohn M., Bauer T., Barz M., Wuttke S., Wagner E. & Lachelt U. (2019), Core-shell functionalized zirconium-pemetrexed coordination nanoparticles as carriers with a high drug content, Advanced Therapeutics 2(11): 1900120.
- Muhl C., Conrad M., Unthan D. & Barz M. (2019), Synthesis and characterization of bisalkylated polysarcosine-based lipopolymers, European Polymer Journal 120: 109223.
- Zimpel A., Danaf N. Al, Steinborn B., Kuhn J., Hohn M., Bauer T., Hirschle P., Schrimpf W., Engelke H., Wagner E., Barz M., Lamb D.C., Lachelt U. & Wuttke S. (2019), Coordinative Binding of Polymers to Metal-Organic Framework Nanoparticles for Control of Interactions at the Biointerface, ACS Nano 13(4): 3884-3895.
- Mantha S., Qi S.H., Barz M. & Schmid F. (2019), How ill-defined constituents produce well-defined nanoparticles: effect of polymer dispersity on the uniformity of copolymeric micelles, Physical Review Materials 3(2): 026002 .
- Birke A., Ling J. & Barz M. (2018), Polysarcosine-containing copolymers: Synthesis, characterization, self-assembly, and applications, Progress in Polymer Science 81: 163-208.
- Settanni G., Schafer T., Muhl C., Barz M. & Schmid F. (2018), Poly-sarcosine and poly(ethylene-glycol) interactions with proteins investigated using molecular dynamics simulations, Computational and Structural Biotechnology Journal 16: 543-550.
- Otter R., Klinker K., Spitzer D., Schinnerer M., Barz M. & Besenius P. (2018), Folding induced supramolecular assembly into pH-responsive nanorods with a protein repellent shell, Chemical Communications 54(4): 401-404.
- Klein P.M., Klinker K., Zhang W., Kern S., Kessel E., Wagner E. & Barz M. (2018), Efficient shielding of polyplexes using heterotelechelic polysarcosines, Polymers 10(6): 689.
- Schäfer O. & Barz M. (2018), Of thiols and disulfides: methods for chemoselective formation of asymmetric disulfides in synthetic peptides and polymers, Chemistry: a European Journal 24(47): 12131-12142.
- Fenaroli F., Repnik U., Xu Y.T., Johann K., Herck S. van, Dey P., Skjeldal F.M., Frei D.M., Bagherifam S., Kocere A., Haag R., Geest B.G. de, Barz M., Russell D.G. & Griffiths G. (2018), Enhanced Permeability and Retention-like Extravasation of Nanoparticles from the Vasculature into Tuberculosis Granulomas in Zebrafish and Mouse Models, ACS Nano 12(8): 8646-8661.
- Muhl C., Schäfer O., Bauer T., Räder H.J. & Barz M. (2018), Poly(S-ethylsulfonyl-l-homocysteine): An α-Helical Polypeptide for Chemoselective Disulfide Formation, Macromolecules 51(20): 8188-8196.
- Otter R., Henke N.A., Berac C., Bauer T., Barz M., Seiffert S. & Besenius P. (2018), Secondary structure-driven hydrogelation using foldable telechelic polymer-peptide conjugates, Macromolecular Rapid Communications 39(17): 1800459.
- Theek B., Baues M., Gremse F., Pola R., Pechar M., Negwer I., Koynov K., Weber B., Barz M., Jahnen-Dechent W., Storm G., Kiessling F. & Lammers T. (2018), Histidine-rich glycoprotein-induced vascular normalization improves EPR-mediated drug targeting to and into tumors, Journal of Controlled Release 282: 25-34.
- Negwer I., Best A., Schinnerer M., Schafer O., Capeloa L., Wagner M., Schmidt M., Mailander V., Helm M., Barz M., Butt H.J. & Koynov K. (2018), Monitoring drug nanocarriers in human blood by near-infrared fluorescence correlation spectroscopy, Nature Communications 9: 5306.
- Beck S., Schultze J., Rader H.J., Holm R., Schinnerer M., Barz M., Koynov K. & Zentel R. (2018), Site-specific DBCO modification of DEC205 antibody for polymer conjugation, Polymers 10(2): 141.
- Weber B., Birke A., Fischer K., Schmidt M. & Barz M. (2018), Solution Properties of Polysarcosine: From Absolute and Relative Molar Mass Determinations to Complement Activation, Macromolecules 51(7): 2653-2661.
- Weber B., Kappel C., Scherer M., Helm M., Bros M., Grabbe S. & Barz M. (2017), PeptoSomes for Vaccination: Combining Antigen and Adjuvant in Polypept(o)ide-Based Polymersomes, Macromolecular Bioscience 17(10): 1700061.
- Klinker K., Schäfer O., Huesmann D., Bauer T., Capelôa L., Braun L., Stergiou N., Schinnerer M., Dirisala A., Miyata K., Osada K., Cabral H., Kataoka K. & Barz M. (2017), Secondary-Structure-Driven Self-Assembly of Reactive Polypept(o)ides: Controlling Size, Shape, and Function of Core Cross-Linked Nanostructures, Angewandte Chemie (International Edition) 56(32): 9608-9613.
- Sato K., Ji W., Palmer L.C., Weber B., Barz M. & Stupp S.I. (2017), Programmable assembly of peptide amphiphile via noncovalent-to-covalent bond conversion, Journal of the American Chemical Society 139(26): 8995-9000.
- Bartneck M., Schlößer C.T., Barz M., Zentel R., Trautwein C., Lammers T. & Tacke F. (2017), Immunomodulatory Therapy of Inflammatory Liver Disease Using Selectin-Binding Glycopolymers, ACS Nano 11(10): 9689-9700.
- Weil T. & Barz M. (2017), From Polymers to Functional Biomaterials, Macromolecular Bioscience 17(10): 1700307.
- Tsvetkova Y., Beztsinna N., Baues M., Klein D., Rix A., Golombek S.K., Rawashdeh W. Al, Gremse F., Barz M., Koynov K., Banala S., Lederle W., Lammers T. & Kiessling F. (2017), Balancing Passive and Active Targeting to Different Tumor Compartments Using Riboflavin-Functionalized Polymeric Nanocarriers, Nano Letters 17(8): 4665-4674.
- Heller P., Zhou J., Weber B., Hobernik D., Bros M., Schmid F. & Barz M. (2017), The Influence of Block Ionomer Microstructure on Polyplex Properties: Can Simulations Help to Understand Differences in Transfection Efficiency?, Small 13(17): 1603694.
- Ahlers P., Frisch H., Holm R., Spitzer D., Barz M. & Besenius P. (2017), Tuning the pH-Switch of Supramolecular Polymer Carriers for siRNA to Physiologically Relevant pH, Macromolecular Bioscience 17(10): 1700111.
- Schafer O., Klinker K., Braun L., Huesmann D., Schultze J., Koynov K. & Barz M. (2017), Combining Orthogonal Reactive Groups in Block Copolymers for Functional Nanoparticle Synthesis in a Single Step, ACS Macro Letters 6(10): 1140-1145.
- Heller P., Hobernik D., Lächelt U., Schinnerer M., Weber B., Schmidt M., Wagner E., Bros M. & Barz M. (2017), Combining reactive triblock copolymers with functional cross-linkers: A versatile pathway to disulfide stabilized-polyplex libraries and their application as pDNA vaccines, Journal of Controlled Release 258: 146-160.
- Hu Q., Rijcken C.J.F., Gaal E. van, Brundel P., Kostkova H., Etrych T., Weber B., Barz M., Kiessling F., Prakash J., Storm G., Hennink W.E. & Lammers T. (2016), Tailoring the physicochemical properties of core-crosslinked polymeric micelles for pharmaceutical applications, Journal of Controlled Release 244(Part B): 314-325.
- Zhou J.J., Barz M. & Schmid F. (2016), Complex formation between polyelectrolytes and oppositely charged oligoelectrolytes, The Journal of Chemical Physics 144(16): 164902.
- Weber B., Seidl C., Schwiertz D., Scherer M., Bleher S., Suss R. & Barz M. (2016), Polysarcosine-based lipids: from lipopolypeptoid micelles to stealth-like lipids in Langmuir Blodgett monolayers, Polymers 8(12): 427.
- Schafer O., Huesmann D. & Barz M. (2016), Poly(S-ethylsulfonyl-L-cysteines) for chemoselective disulfide formation, Macromolecules 49(21): 8146-8153.
- Fokina A., Klinker K., Braun L., Jeong B.G., Bae W.K., Barz M. & Zentel R. (2016), Multidentate polysarcosine-based ligands for water-soluble quantum dots, Macromolecules 49(10): 3663-3671.
- Schafer O., Huesmann D., Muhl C. & Barz M. (2016), Rethinking cysteine protective groups: S-alkylsulfonyl-L-cysteines for chemoselective disulfide formation, Chemistry: a European Journal 22(50): 18085-18091.
- Huesmann D., Schafer O., Braun L., Klinker K., Reuter T. & Barz M. (2016), Exploring new activating groups for reactive cysteine NCAs, Tetrahedron Letters 57(10): 1138-1142.
- Tappertzhofen K., Beck S., Montermann E., Huesmann D., Barz M., Koynov K., Bros M. & Zentel R. (2016), Bioreducible poly-L-lysine-poly[HPMA] block copolymers obtained by RAFT-polymerization as efficient polyplex-transfection reagents, Macromolecular Bioscience 16(1): 106-120.
- Talelli M., Barz M., Rijcken C.J.F., Kiessling F., Hennink W.E. & Lammers T. (2015), Core-crosslinked polymeric micelles: principles, preparation, biomedical applications and clinical translation, Nano Today 10(1): 93-117.
- Heller P., Mohr N., Birke A., Weber B., Reske-Kunz A., Bros M. & Barz M. (2015), Directed interactions of block copolypept(o) ides with mannose-binding receptors: PeptoMicelles targeted to cells of the innate immune system, Macromolecular Rapid Communications 15(1): 63-73.
- Barz M., Gotze S., Loges N., Schuler T., Theato P., Tremel W. & Zentel R. (2015), Well-defined carbohydrate-based polymers in calcium carbonate crystallization: influence of stereochemistry in the polymer side chain on polymorphism and morphology, European Polymer Journal 69: 628-635.
- Heller P., Weber B., Birke A. & Barz M. (2015), Synthesis and sequential deprotection of triblock copolypept(o)ides using orthogonal protective group chemistry, Macromolecular Rapid Communications 36(1): 38-44.
- Holm R., Klinker K., Weber B. & Barz M. (2015), Synthesis of amphiphilic block copolypept(o)ides by bifunctional initiators: making PeptoMicelles redox sensitive, Macromolecular Rapid Communications 36(23): 2083-2091.
- Huesmann D., Sevenich A., Weber B. & Barz M. (2015), A head-to-head comparison of poly(sarcosine) and poly(ethylene glycol) in peptidic, amphiphilic block copolymers, Polymer 67: 240-248.
- Klinker K. & Barz M. (2015), Polypept(o) ides: hybrid systems based on polypeptides and polypeptoids, Macromolecular Rapid Communications 36(22): 1943-1957.
- Barz M., Gotze S., Loges N., Schuler T., Theato P., Tremel W. & Zentel R. (2015), Well-defined carbohydrate-based polymers in calcium carbonate crystallization: influence of stereochemistry in the polymer side chain on polymorphism and morphology, European Polymer Journal 69: 628-635.
- Holm R., Klinker K., Weber B. & Barz M. (2015), Synthesis of amphiphilic block copolypept(o)ides by bifunctional initiators: making PeptoMicelles redox sensitive, Macromolecular Rapid Communications 36(23): 2083-2091.
- Hortz C., Birke A., Kaps L., Decker S., Wachtersbach E., Fischer K., Schuppan D., Barz M. & Schinidt M. (2015), Cylindrical brush polymers with polysarcosine side chains: a novel biocompatible carrier for biomedical applications, Macromolecules 48(7): 2074-2086.
- Schieferstein H., Kelsch A., Reibel A., Koynov K., Barz M., Buchholz H.G., Bausbacher N., Thews O., Zentel R. & Ross T.L. (2014), F-18-radiolabeling, preliminary evaluation of folate-pHPMA conjugates via PET, Macromolecular Bioscience 14(10): 1396-1405.
- Heller P., Birke A., Huesmann D., Weber B., Fischer K., Reske-Kunz A., Bros M. & Barz M. (2014), Introducing PeptoPlexes: polylysine-block-polysarcosine based polyplexes for transfection of HEK 293T cells, Macromolecular Bioscience 14(10): 1380-1395.
- Nuhn L., Barz M. & Zentel R. (2014), New perspectives of HPMA-based copolymers derived by post-polymerization modification, Macromolecular Bioscience 14(5): 607-618.
- Birke A., Huesmann D., Kelsch A., Weilbacher M., Xie J., Bros M., Bopp T., Becker C., Landfester K. & Barz M. (2014), Polypeptoid-block-polypeptide copolymers: synthesis, characterization, and application of amphiphilic block copolypept(o)ides in drug formulations and miniemulsion techniques, Biomacromolecules 15(2): 548-557.
- Huesmann D., Birke A., Klinker K., Turk S., Rader H.J. & Barz M. (2014), Revisiting secondary structures in NCA polymerization: influences on the analysis of protected polylysines, Macromolecules 47(3): 928-936.
- Luxenhofer R., Barz M. & Schillmeier M. (2014), Quo Vadis Nanomedicine?, Nanomedicine 9(14): 2083-2086.
- Mohr N., Barz M., Forst R. & Zentel R. (2014), A deeper insight into the postpolymerization modification of polypenta fluorophenyl methacrylates to poly(N-(2-hydroxypropyl) methacrylamide), Macromolecular Rapid Communications 35(17): 1522-1527.
- Tappertzhofen K., Metz V.V., Hubo M., Barz M., Postina R., Jonuleit H. & Zentel R. (2013), Synthesis of maleimide-functionalyzed HPMA-copolymers and in vitro characterization of the aRAGE- and human immunoglobulin (huIgG)polymer conjugates, Macromolecular Bioscience 13(2): 203-214.
- Dietzsch M., Barz M., Schueler T., Klassen S., Schreiber M., Susewind M., Loges N., Lang M., Hellmann N., Fritz M., Fischer K., Theato P., Kuhnle A., Schmidt M., Zentel R. & Tremel W. (2013), PAA-PAMPS copolymers as an efficient tool to control CaCO3 scale formation, Langmuir 29(9): 3080-3088.
- Barz M., Duro-Castano A. & Vicent M.J. (2013), A versatile post-polymerization modification method for polyglutamic acid: synthesis of orthogonal reactive polyglutamates and their use in "click chemistry", Polymer Chemistry 4(10): 2989-2994.
- Conejos-Sanchez I., Duro-Castano A., Birke A., Barz M. & Vicent M.J. (2013), A controlled and versatile NCA polymerization method for the synthesis of polypeptides, Polymer Chemistry 4(11): 3182-3186.
- Shukoor M.I., Natalio F., Tahir M.N., Barz M., Weber S., Brochhausen C., Zentel R., Schreiber L.M., Brieger J. & Tremel W. (2012), CpG-DNA loaded multifunctional MnO nanoshuttles for TLR9-specific cellular cargo delivery, selective immune-activation and MRI, Journal of Materials Chemistry B 22(18): 8826-8834.
- Kelsch A., Tomcin S., Rausch K., Barz M., Mailander V., Schmidt M., Landfester K. & Zentel R. (2012), HPMA Copolymers as surfactants in the preparation of biocompatible nanoparticles for biomedical application, Biomacromolecules 13(12): 4179-4187.
- Barz M., Arminan A., Canal F., Wolf F., Koynov K., Frey H., Zentel R. & Vicent M.J. (2012), P(HPMA)-block-P(LA) copolymers in paclitaxel formulations: polylactide stereochemistry controls micellization, cellular uptake kinetics, intracellular localization and drug efficiency, Journal of Controlled Release 163(1): 63-74.
- Barz M., Luxenhofer R., Zentel R. & Vicent M.J. (2011), Overcoming the PEG-addiction: well-defined alternatives to PEG, from structure-property relationships to better defined therapeutics, Polymer Chemistry 2(9): 1900-1918.
- Hemmelmann M., Knoth C., Schmitt U., Allmeroth M., Moderegger D., Barz M., Koynov K., Hiemke C., Rosch F. & Zentel R. (2011), HPMA based amphiphilic copolymers mediate central nervous effects of domperidone, Macromolecular Rapid Communications 32(9-10): 712-717.
- Herth M.M., Barz M., Jahn M., Zentel R. & Rosch F. (2010), As-72/74-labeling of HPMA based polymers for long-term in vivo PET imaging, Bioorganic and Medicinal Chemistry Letters 20(18): 5454-5458.
- Scheibe P., Barz M., Hemmelmann M. & Zentel R. (2010), Langmuir-Blodgett films of biocompatible poly(HPMA)-block-poly(lauryl methacrylate) and poly(HPMA)-random-poly(lauryl methacrylate): influence of polymer structure on membrane formation and stability, Langmuir 26(8): 5661-5669.
- Barz M., Canal F., Koynov K., Zentel R. & Vicent M.J. (2010), Synthesis and in vitro evaluation of defined HPMA folate conjugates: influence of aggregation on folate receptor (FR) mediated cellular uptake, Biomacromolecules 11(9): 2274-2282.
- Barz M., Wolf F.K., Canal F., Koynov K., Vicent M.J., Frey H. & Zentel R. (2010), Synthesis, characterization and preliminary biological evaluation of P(HPMA)-b-P(LLA) copolymers: a new type of functional biocompatible block copolymer, Macromolecular Rapid Communications 31(17): 1492-1500.
- Herth M.M., Barz M., Moderegger D., Allmeroth M., Jahn M., Thews O., Zentel R. & Rosch F. (2009), Radioactive labeling of defined HPMA-based polymeric structures using [F-18]FETos for in vivo imaging by positron emission tomography, Biomacromolecules 10(7): 1697-1703.
- Barz M., Luxenhofer R., Zentel R. & Kabanov A.V. (2009), The uptake of N-(2-hydroxypropyl)-methacrylamide based homo, random and block copolymers by human multi-drug resistant breast adenocarcinoma cells, Biomaterials 30(29): 5682-5690.
- Shukoor M.I., Natalio F., Tahir M.N., Wiens M., Tarantola M., Therese H.A., Barz M., Weber S., Terekhov M., Schroder H.C., Muller W.E.G., Janshoff A., Theato P., Zentel R., Schreiber L.M. & Tremel W. (2009), Pathogen-mimicking MnO nanoparticles for selective activation of the TLR9 pathway and imaging of cancer cells, Advanced Functional Materials 19(23): 3717-3725.
- Tahir M.N., Natalio F., Berger R., Barz M., Theato P., Schroder H.C., Muller W.E.G. & Tremel W. (2009), Growth of fibrous aggregates of silica nanoparticles: fibre growth by mimicking the biogenic silica patterning processes, Soft Matter 5(19): 3657-3662.
- Wang J.J., Tahir M.N., Kappl M., Tremel W., Metz N., Barz M., Theato P. & Butt H.J. (2008), Influence of binding-site density in wet bioadhesion, Advanced Materials 20(20): 3872-3876.
- Scientific Advisory Board Member