Linda Aulin
Universitair docent
- Naam
- Dr. L.B.S. Aulin
- Telefoon
- 071 5272727
- l.b.s.aulin@lacdr.leidenuniv.nl
- ORCID iD
- 0000-0003-4840-5704
Nieuws
-
LACDR start nascholingsprogramma voor innovatieve geneesmiddelontwikkeling -
Bij de volgende pandemie versnelt dit wiskundig model de zoektocht naar een behandeling -
Onderzoekers gaan de strijd aan met antibioticaresistente bacteriën -
Antibioticaresistentie op een slimme manier bestrijden
-
Leids promovenditeam door naar finale internationale farmacologische wedstrijd
Universitair docent
- Faculteit der Wiskunde en Natuurwetenschappen
- LACDR
- Divisie Systems Pharmacology and Pharmacy
- Alarcon Rios A.C., Zwep L.B., Vriesendorp B., Knibbe C.A.J., Ciofu O., Liakopoulos A., Aulin L.B.S., Rozen D.E. & Hasselt J.G.C. van (2025), Colistin resistance dynamics in Pseudomonas aeruginosa under biofilm and planktonic growth, Antimicrobial Agents and Chemotherapy 69(10): e00421-25.
- Tandar S.T., Clercq A. de, Aulin L.B.S., Biesen W. van, Delanghe S, Vanommeslaeghe F., Paepe P. de, Hasselt J.G.C. van Cock P.A. de & Eloot S. (2025), Model-based optimisation for teicoplanin dosing in patients undergoing maintenance haemodialysis, Clinical Microbiology and Infection : .
- Tandar S.T., Aulin L.B.S., Leemkuil E. M.J., Liakopoulos A. & Hasselt J.G.C. van (2024), Semi-mechanistic modeling of resistance development to β-lactam and β-lactamase-inhibitor combinations, Journal of Pharmacokinetics and Pharmacodynamics 51: 199-211.
- Liu F., Aulin L.B.S. & Manson M.L. Krekels E.H.J. Hasselt J.G.C. van (2023), Unraveling the effects of acute inflammation on pharmacokinetics: a model-based analysis focusing on renal glomerular filtration rate and cytochrome P450 3A4-mediated metabolism, European Journal of Drug Metabolism and Pharmacokinetics 48: 623–631.
- Healy K., Aulin L.B.S., Freij U., Ellerstad M., Brückle L., Hillmering H., Svae T.E., Broliden K. & Gustafsson R. (2023), Prevalence of parvovirus B19 viremia among German blood donations and the relationship to ABO and rhesus blood group antigens, The Journal of Infectious Diseases 227(10): 1214-1218.
- Liakopoulos A., Aulin L.B.S., Buffoni M., Fragkiskou E., Hasselt J.G.C. van & Rozen D.E. (2022), Allele-specific collateral and fitness effects determine the dynamics of fluoroquinolone resistance evolution, Proceedings of the National Academy of Sciences 119(18): e2121768119.
- Aulin L.B.S., Kleijburg A., Moerland M. & Hasselt J.G.C. van (2022), Characterizing the kinetics of presepsin and associated inflammatory biomarkers in human endotoxemia, Inflammation Research 71(9): 999-1001.
- Healy K., Freij U., Ellerstad M., Aulin L.B.S., Brückle L., Hillmering H., Chen M.S. & Gustafsson R. (2022), Evaluating the prevalence of Hepatitis E virus infection in a large cohort of European blood donors, 2015-2018, Journal of Viral Hepatitis 29(9): 835-839.
- Liu F., Aulin L.B.S., Guo T., Krekels E.H.J., Moerland M., Graaf P.H. van der & Hasselt J.G.C. van (2022), Modelling inflammatory biomarker dynamics in a human lipopolysaccharide (LPS) challenge study using delay differential equations, British Journal of Clinical Pharmacology 88(12): 5420-5427.
- Aulin L.B.S., Tandar S.T., Zijp T. van, Ballegooie E. van, Graaf P.H. van der, Saleh M.A.A.E.W., Välitalo P. & Hasselt J.G.C. van (2022), Physiologically based modelling framework for prediction of pulmonary pharmacokinetics of antimicrobial target site concentrations, Clinical Pharmacokinetics 61: 1735-1748.
- Aulin L.B.S. (14 december 2022), Quantitative pharmacology of antimicrobials (Dissertatie. Leiden Academic Centre for Drug Research (LADCR), Faculty of Science, Leiden University). Promotor(en) en copromotor(en): Graaf P.H. van der, Hasselt J.G.C. van.
- Aulin L.B.S., De Paepe. P., Dhont E., Jaeger A. de, Vande Walle J., Vandenberghe W., McWhinney B.C., Ungerer J.P.J., Hasselt J.G.C. van & Cock P.A.J.G. de (2021), Population pharmacokinetics of unbound and total teicoplanin in critically ill pediatric patients, Clinical Pharmacokinetics 60: 353-363.
- Aulin L.B.S., Koumans C.I.M., Haakman Y., Os W. van, Kraakman M.E.M., Gooskens J., Smits W.K., Liakopoulos A. & Hasselt J.G.C. van (2021), Distinct evolution of colistin resistance associated with experimental resistance evolution models in Klebsiella pneumoniae, Journal of Antimicrobial Chemotherapy 76(2): 533-535.
- Aulin L.B.S., Lange D.W. de, Saleh M.A.A., Graaf P.H. van der, Völler S. & Hasselt J.G.C. (2021), Biomarker-guided individualization of antibiotic therapy, Clinical Pharmacology & Therapeutics 110(2): 346-360.
- Aulin L.B.S., Liakopoulos A., Graaf P.H. van der, Rozen D.E. & Hasselt J.G.C. (2021), Design principles of collateral sensitivity-based dosing strategies, Nature Communications 12: 5691.
- Aulin L.B.S., Valitalo P.A., Rizk M.L., Visser S.A.G., Rao G., Graaf P.H. van der & Hasselt J.G.C. van (2018), Validation of a Model Predicting Anti-infective Lung Penetration in the Epithelial Lining Fluid of Humans, Pharmaceutical Research 35(2): 26.