Universiteit Leiden

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Proefschrift

The use of activity based protein profiling to study proteasome biology

Promotor: H.S. Overkleeft, Co-Promotor: B.I. Florea

Auteur
Guillem Paniagua Soriano
Datum
11 februari 2016
Links
Thesis in Leiden Repository

The work described in this thesis focuses on the characterization of proteasome directed activity-based probes (ABPs) as well as on the adaptation mechanisms that make multiple myeloma derived cell lines resistant against proteasome inhibitors (PIs).