Proefschrift
Substrates and inhibitors to study and modulate ER-I α-glucosidase activity
This thesis describes research aimed at discovering inhibitors selective for either of the two endoplasmic reticulum α-glucosidases, ER-I and ER-II, with the overarching goal of discovering new antiviral agents to treat viruses that rely on host N-glycosylation for proliferation.
- Auteur
- J.J.A. Heming
- Datum
- 16 januari 2026
- Links
- Thesis in Leiden Repository
It also describes assays that measure the activity of these enzymes and the effects of inhibitors on them.