Tan Zhang
Promovendus / gast
- Naam
- T. Zhang MSc
- Telefoon
- 071 5272727
- t.zhang@lacdr.leidenuniv.nl
- ORCID iD
- 0000-0001-9355-2370
Promovendus / gast
- Faculteit der Wiskunde en Natuurwetenschappen
- LACDR
- Divisie Systems Pharmacology and Pharmacy
- Zhang T. (10 maart 2026), Individualization of drug clearance predictions and dose regimens in patients with obesity using pharmacometric approaches (Dissertatie. Leiden Academic Centre for Drug Research (LACDR), Faculty of Science, Leiden University). Promotor(en) en copromotor(en): Knibbe C.A.J., Krekels E.H.J.
- Zhang T., Calvier E.A.M., Krekels E.H.J. & Knibbe C.A.J. (2025), The impact of drug properties and severity of obesity on renal drug clearance through glomerular filtration and active tubular secretion: a systematic analysis using PBPK modeling, Pharmaceutical Research 42: 1079-1088.
- Zhang T., Calvier E.A.M., Krekels E.H.J. & Knibbe C.A.J. (2024), Impact of obesity on hepatic drug clearance: what are the influential variables?, AAPS Journal 26(3): 59.
- Zhang T., Smit C., Sherwin C.M.T., Knibbe C.A.J. & Krekels E.H.J. (2023), Vancomycin clearance in obese adults is not predictive of clearance in obese adolescents, Clinical Pharmacokinetics 62(5): 749-759.
- Zhang T., Krekels E.H.J., Smit C., Dongen E.P.A. van, Brüggeman R.J.M. & Knibbe C.A.J. (2023), How to dose vancomycin in overweight and obese patients with varying renal (dys)function in the novel era of AUC 400–600 mg·h/L-targeted dosing, Clinical Pharmacokinetics 63(1): 79-91.
- Zhang T., Krekels E.H.J., Smit C. & Knibbe C.A.J. (2022), Drug pharmacokinetics in the obese population: challenging common assumptions on predictors of obesity-related parameter changes, Expert Opinion on Drug Metabolism & Toxicology 18(10): 657-674.