Universiteit Leiden

nl en

Kees van den Hondel

Emeritus hoogleraar Moleculaire microbiologie van filamenteuse schimmels

Naam
Prof.dr. C.A.M.J.J. van den Hondel
Telefoon
+31 71 527 5056
E-mail
c.a.m.van.den.hondel@biology.leidenuniv.nl

Voor meer informatie, zie de Engelse versie.

Emeritus hoogleraar Moleculaire microbiologie van filamenteuse schimmels

  • Wiskunde en Natuurwetenschappen
  • Instituut Biologie Leiden
  • IBL Biotechnology & Health

Werkadres

Sylvius
Sylviusweg 72
2333 BE Leiden
Kamernummer 4.4.15

Contact

  • Paege N., Jung S., Schape P., Muller-Hagen D., Ouedraogo J.P., Heiderich C., Jedamzick J., Nitsche B.M., Hondel C.A.M.J.J. van den, Ram A.F.J. & Meyer V. (2016), A Transcriptome Meta-Analysis Proposes Novel Biological Roles for the Antifungal Protein AnAFP in Aspergillus niger, PLOS ONE 11(11): 0165755.artikel in tijdschrift (refereed)
  • Park J., Hulsman M., Arentshorst M., Breeman M., Alazi E., Lagendijk E.L., Rocha M.C., Malavazi I., Nitsche B.M., Hondel C.A.M.J.J. van den, Meyer V. & Ram A.F.J. (2016), Transcriptomic and molecular genetic analysis of the cell wall salvage response of Aspergillus niger to the absence of galactofuranose synthesis, CELLULAR MICROBIOLOGY 18(9): 1268-1284.artikel in tijdschrift (refereed)
  • Rocha M.C., Tadini M.F.J.H., Godoy K.F. de, Castro P.A. de, Hori J.I., Cunha A.F. da, Arentshorst M., Ram A.F.J., Hondel C.A.M.J.J. van den, Goldman G.H. & Malavazi I. (2016), Aspergillus fumigatus MADS-Box Transcription Factor rlmA Is Required for Regulation of the Cell Wall Integrity and Virulence, G3-GENES GENOMES GENETICS 6(9): 2983-3002.artikel in tijdschrift (refereed)
  • Ram A.F.J., Voshol G.P., Meyer V. & Hondel C.A.M.J.J. van den (2015), GTP-binding protein Era: a novel gene target for biofuel production., BMC Biotechnology 15(21).artikel in tijdschrift (refereed)
  • Angelique C.W. Franken, Beatrix E. Lechner, Ernst R.Werner, Hubertus Haas, B.Christien Lokman, Arthur F. J. Ram, Cees A. M. J. J. van den Hondel, Sandra deWeert & Peter J. Punt (2014), Genome mining and functional genomics for siderophore production in Aspergillus niger., Briefings in Functional Genomics Advance Access (14-05).artikel in tijdschrift (refereed)
  • Markus RM Fiedler, Annett Lorenz, Benjamin M Nitsche, Cees AMJJ van den Hondel, Arthur FJ Ram & Vera Meyer (2014), The capacity of Aspergillus niger to sense and respond to cell wall stress requires at least three transcription factors: RlmA, MsnA and CrzA, Fungal Biology and Biotechnology .artikel in tijdschrift (refereed)
  • Park JP, Tefsen B, Arentshorst M, Lagendijk E, van den Hondel CAMJJ, van Die I & Ram AFJ (2014), Identification of the UDP-glucose-4-epimerase required for galactofuranose biosynthesis and galactose metabolism in A. niger, Fungal Biology and Biotechnology .artikel in tijdschrift (refereed)
  • Fiedler M.R.M., Lorenz A., Nitsche B.M., Hondel C.A.M.J.J. van den, Ram A.F.J. & Meyer V. (2014), The capacity of Aspergillus niger to sense and respond to cell wall stress requires at least three transcription factors: RlmA, MsnA and CrzA., Fungal Biology and Biotechnology 1(5).artikel in tijdschrift (refereed)
  • Franken A.C., Lokman B.C., Ram A.F.J., Hondel C.A.M.J.J. van den, Weert S. de & Punt P.J. (2012), Analysis of the role of the A. niger aminolevulinic acid synthase (hemA) gene illustrates the difference between regulation of yeast and fungal heme and siroheme dependent pathways., FEMS Microbiology Letters 335(2): 104-112.artikel in tijdschrift (refereed)
  • Carvalho N.D.S.P., Jørgensen T.R., Arentshorst M., Nitsche B.M., Hondel C.A.M.J.J. van den, Archer D.B. & Ram A.F.J. (2012), Genome-wide expression analysis upon constitutive activation of the HacA bZIP transcription factor in Aspergillus niger reveals a coordinated cellular response to counteract ER stress., BMC Genomics 30(13): 350.artikel in tijdschrift (refereed)
  • Ouedraogo J.P., Lagendijk E.L., Hondel C.A.M.J.J. van den, Ram A.F.J. & Meyer V. (2012), Screening for compounds exerting antifungal activities.. In: Vijai Kumar Gupta Maria G. Tuohy, Manimaran Ayyachamy Anthonia O'Donovan Kevin M. Turner (Red.) Laboratory Protocols in Fungal Biology. New York: Humana Press/Springer. 225-230.boekdeel
  • Meyer V., Minkwitz S., Schütze T., Hondel C.A.M.J.J. van den & Ram A.F.J. (2011), The Aspergillus niger RmsA protein - a node in a genetic network?, Onbekend 3: 1-3.artikel in tijdschrift (refereed)
  • Carvalho N.D.S.P., Arentshorst M., Kooistra R., Stam H., Sagt C.M., Hondel C.A.M.J.J. van den & Ram A.F.J. (2011), Effects of a defective ERAD pathway on growth and heterologous protein production in Aspergillus niger, Applied microbiology and biotechnology 89: 357-373.artikel in tijdschrift (refereed)
  • Jørgensen T.R., Park J.-H., Arentshorst M., Welzen A.M. van, Lamers G., VanKuyk P.A., Damveld R.A., Hondel C.A.M.J.J. van den, Nielsen K.F., Frisvad J.C. & Ram A.F.J. (2011), The molecular and genetic basis of conidial pigmentation in Aspergillus niger, Fungal genetics and biology 48: 544-553.artikel in tijdschrift (refereed)
  • Kwon M.J., Arentshorst M., Roos E.D., Hondel C.A.M.J.J. van den, Meyer V. & Ram A.F.J. (2011), Functional characterization of Rho GTPases in Aspergillus niger uncovers conserved and diverged roles of Rho proteins within filamentous fungi, Molecular Microbiology 79: 1151-1167.artikel in tijdschrift (refereed)
  • Franken A.C., Lokman B.C., Ram A.F.J., Punt P.J., Hondel C.A.M.J.J. van den & Weert S. de (2011), Heme biosynthesis and its regulation: towards understanding and improvement of heme biosynthesis in filamentous fungi., Applied microbiology and biotechnology 91: 447-460.artikel in tijdschrift (refereed)
  • Jørgensen T.R., Nielsen K.F., Arentshorst M., Park J., Hondel C.A.M.J.J. van den, Frisvad J.C. & Ram A.F.J. (2011), Submerged Conidiation and Product Formation by Aspergillus niger at Low Specific Growth Rates Are Affected in Aerial Developmental Mutants, Applied Environmental Microbiology 77: 5270-5277.artikel in tijdschrift (refereed)
  • Meyer V., Wanka F., Gent J. van, Arentshorst M., Hondel C.A.M.J.J. van den & Ram A.F.J. (2011), Fungal gene expression on demand: An inducible, tunable and metabolism independent expression system for Aspergillus niger., Applied Environmental Microbiology 77: 2975-2983.artikel in tijdschrift (refereed)
  • Jørgensen T.R., Park J.-H., Arentshorst M., Welzen A.M. van, Lamers G.E.M., VanKuyk P.A., Damveld R.A., Hondel C.A.M.J.J. van den, Nielsen K.F., Frisvad J.C. & Ram A.F.J. (2011), The molecular and genetic basis of conidial pigmentation in Aspergillus niger., Fungal genetics and biology 48: 544-553.artikel in tijdschrift (refereed)
  • Carvalho N.D.S.P., Arentshorst M., Weenink X., Punt P.J., Hondel C.A.M.J.J. van den & Ram A.F.J. (2011), Functional YFP-tagging of the essential GDP-mannose transporter reveals an important role for the secretion related small GTPase SrgC protein in maintenance of Golgi bodies in Aspergillus niger., Onbekend 115: 253-264.artikel in tijdschrift (refereed)
  • Abdel-Farid B., Jahangir M., Mustafa N.R., Dam N. van, Kim H.K., Hondel C.A.M.J.J. van den, Choi Y.H. & Verpoorte R. (2010), Glucosinolate Profiling of Brassica rapa in Response to Infection by Leptosphaeria maculans and Fusarium oxysporum, Onbekend 38: 612-620.artikel in tijdschrift (refereed)
  • Jørgensen T.R., Nitsche B.M., Lamers G.E., Arentshorst M., Hondel C.A.M.J.J. van den & Ram A.F.J. (2010), Transcriptomic insights into the physiology of Aspergillus niger approaching a specific growth rate of zero, Applied and Environmental Microbiology 76(16): 5344-5355.artikel in tijdschrift (refereed)
  • Biesbeke R. te, Levasseur A., Boussier A., Record E., Hondel C.A.M.J.J. van den & Punt P.J. (2010), Phylogeny of fungal hemoglobins and expression analysis of the Aspergillus oryzae flavohemoglobin gene fhbA during hyphal growth, Onbekend 114(2-3): 135-143.artikel in tijdschrift (refereed)
  • Abdel-Farid I.B., Jahangir M., Hondel C.A.M.J.J. van den, Kim H.K., Choi Y.H. & Verpoorte R. (2009), Fungal infection-induced metabolites in Brassica rapa., Plant Science 176: 608-615.artikel in tijdschrift (refereed)
  • Jacobs D., Olsthoorn M., Maillet I., Akeroyd M., Breestraat S., Donkers S., Hoeven R. van der, Hondel C.A.M.J.J. van den, Kooistra R., Lapointe T., Menke H., Meulenberg R., Misset M., Müller W., Peij N., Ram A.F.J., Rodriguez S., Roelofs M., Roubos H., Tilborg M. van, Verkleij A., Pel H., Stam H. & Sagt C.M. (2009), Effective lead selection for improved protein production in Aspergillus niger based on integrated genomics., Fung. Genet. Biol. 46(Suppl. 1): S141-152.artikel in tijdschrift (refereed)
  • Jørgensen T.R., Goosen T., Hondel C.A.M.J.J. van den, Ram A.F.J. & Iversen J.J. (2009), Transcriptomic comparison of Aspergillus niger growing on two different sugars reveals coordinated regulation of the secretory pathway., BMC Genomics 23: 10-44.artikel in tijdschrift (refereed)
  • Ravalason H., Herpoël-Gimbert I., Record E., Bertaud F., Grisel S., Weert S. de, Hondel C.A.M.J.J. van den, Asther M., Petit-Conil M. & Sigoillot J.C. (2009), Fusion of a family 1 carbohydrate binding module of Aspergillus niger to the Pycnoporus cinnabarinus laccase for efficient softwood kraft pulp biobleaching ., Journal of Bacteriology (IF:2.565).artikel in tijdschrift (refereed)
  • Meyer V., Arentshorst M., Flitter S.J., Nitsche B.M., Kwon M.J., Reynaga-Pena C.G., Bartnicki-Garcia S., Hondel C.A.M.J.J. van den & Ram A.F.J. (2009), Reconstruction of signalling networks regulating fungal morphogenesis by transcriptomics., Eukaryotic Cell 8: 1677-1691.artikel in tijdschrift (refereed)
  • Abdel-Farid I.B., Choi Y.H., Kim H.K., Hondel C.A.M.J.J. van den, Meijden E. van der & Verpoorte R. (2008), The role of secondary metabolites in Arabidopsis and Brassica in the interaction with fungi, Current Topics in Microbiology and Immunology.artikel in tijdschrift (refereed)
  • Damveld R.A., Franken A., Arentshorst M., Punt P.J., Klis F.M., Hondel C.A.M.J.J. van den & Ram A.F.J. (2008), A novel screening method for cell wall mutants in Aspergillus niger identifies UDP-galactopyranose mutase as an important protein in fungal cell wall biosynthesis, Genetics 178: 873-881.artikel in tijdschrift (refereed)
  • Yuan X., Kaaij R.M. van der, Hondel C.A.M.J.J. van den, Punt P.J., Maarel M.J., Dijkhuizen L. & Ram A.F.J. (2008), Aspergillus niger genome-wide analysis reveals a large number of novel alpha-glucan acting enzymes with unexpected expression profiles, Molecular Genet. Genomics 279: 545-561.artikel in tijdschrift (refereed)
  • Yuan X., Roubos J.A., Hondel C.A.M.J.J. van den & Ram A.F.J. (2008), Identification of InuR, a new Zn(II)2Cys6 transcriptional activator involved in the regulation of inulinolytic genes in Aspergillus niger, Molecular Genet. Genomics 279: 11-26.artikel in tijdschrift (refereed)
  • Michielse C.B., Hooykaas P.J.J., Hondel C.A.M.J.J. van den & Ram A.F.J. (2008), Agrobacterium-mediated transformation of the filamentous fungus Aspergillus awamori, Nature Protocols 3: 1671-1678.artikel in tijdschrift (refereed)
  • Abdel-Farid I.B., Jahangir M., Mustafa N.R., Dam N. van, Hondel C.A.M.J.J. van den, Kim H.K., Choi Y.H. & Verpoorte R. (2008), Glucosinolate Profiling of Brassica rapa in Response to Infection by Leptosphaeria maculans and Fusarium oxysporum, Journal of Liquid Chromatography and Related Technologies.artikel in tijdschrift (refereed)
  • Jacobs D.I., Olsthoorn M.M., Maillet I., Akeroyd M., Breestraat S., Donkers S., Hoeven R.A.M. van der, Hondel C.A.M.J.J. van den, Kooistra R.A., Lapointe T., Menke H., Meulenberg R., Misset M., Muller W.H., Peij N.N. van, Ram A.F.J., Rodriguez S., Roelofs M.S., Roubos J.A., Tilborg M.W. van, Verkleij A.J., Pel H.J., Stam H. & Sagt C.M. (2008), Effective lead selection for improved protein production in Aspergillus niger based on integrated genomics, Fungal genetics and biology.artikel in tijdschrift (refereed)
  • Jorgensen T.R., Goosen T., Hondel C.A.M.J.J. van den, Ram A.F.J. & Iversen J.J.L. (2008), Transcriptomic comparison of Aspergillus niger growing on two different sugars reveals coordinated regulation of the secretory pathway, BMC Genomics.artikel in tijdschrift (refereed)
  • Meyer V., Arentshorst M., Hondel C.A.M.J.J. van den & Ram A.F.J. (2008), The polarisome component SpaA localises to hyphal tips of Aspergillus niger and is important for polar growt, Fungal genetics and biology 45: 152-164.artikel in tijdschrift (refereed)
  • Wortman J.R., Gilsenan M., Joardar V., Deegan J., Hondel C.A.M.J.J. van den & et al .... (2008), The 2008 update of the Aspergillus nidulans genome annotation: A community effort, Fungal genetics and biology.artikel in tijdschrift (refereed)
  • Guillemette T., Peij N.N. van, Goosen T., Lanthaler K., Robson G.D., Hondel C.A.M.J.J. van den, Stam H. & Archer D.A. (2007), Genomic analysis of the secretion stress response in the enzyme-producing cell factory Aspergillus niger, BMC Genomics 8: 158.artikel in tijdschrift (refereed)
  • Meyer V., Damveld R.A., Arentshorst M., Stahl U., Hondel C.A.M.J.J. van den & Ram A.F.J. (2007), Survival in the presence of antifungals: genome-wide expression profiling of Aspergillus niger in response to sublethal concentrations of caspofungin and fenpropimorph, Journal of Biological Chemistry 282: 32935-32948.artikel in tijdschrift (refereed)
  • Meyer V., Arentshorst M., El-Ghezal A., Drews A.C., Kooistra R.A., Hondel C.A.M.J.J. van den & Ram A.F.J. (2007), Highly efficient gene targeting in the Aspergillus niger kusA mutant, Journal of Biotechnology 128: 770-775.artikel in tijdschrift (refereed)
  • Meyer V., Arentshorst M., Hondel C.A.M.J.J. van den & Ram A.F.J. (2007), The polarisome component SpaA localises to hyphal tips of Aspergillus niger and is important for polar growth, Genet. Biol. 45: 152-164.artikel in tijdschrift (refereed)
  • Pel H.J., Winde J.H. de, Archer D.B., Dyer P.S., Hofmann G., Schaap P., Turner G., Vries R.P. de, Albang R., Albermann K., Andersen M.R., Bendtsen J.D., Benen J.A., Breestraat S., Caddick M.X., Contreras R., Cornell M., Coutinho P.M., Danchin E.G., Debets A.J., Dekker P., Dijck P. van, Dijkhuizen L., Driessen A.J., d'Enfert C., Geysens S., Goosen C., Groot G.S., Groot P.W. de, Guillemette T., Henrissat B., Herweijer M., Hombergh J.P. van den, Hondel C.A.M.J.J. van den, Heijden R. van der, Kaaij R.M. van der, Klis F.M., Kools H., Kubicek C.P., Kuyk P.A. van, Lauber J., Lu X., Maarel M.J., Meulenberg R., Menke H., Mortimer M.A., Nielsen J., Oliver S.G., Olsthoorn M., Pal K., Peij N.N. van, Ram A.F.J., Rinas U., Roubos J.A., Sagt C.M., Schmoll M., Sun J., Ussery D., Varga J., Vervecken W., Vondervoort P.J.I. van de, Wedler H., Wosten H.A., Zeng A.P., Ooyen A.J. van, Visser J. & Stam H. (2007), Genome sequencing and analysis of the versatile cell factory Aspergillus niger CBS 513.88, National Biotechnology 25: 221-231.artikel in tijdschrift (refereed)
  • Vondervoort P.J.I. van de, Langeveld S.M.J., Visser J., Peij N.N. van, Pel H.J., Hondel C.A.M.J.J. van den & Ram A.F.J. (2007), Identification of a mitotic recombination hotspot on chromosome III of the asexual fungus Aspergillus niger and its possible correlation with [corrected] elevated basal transcription, Current Genetics 52: 107-114.artikel in tijdschrift (refereed)
  • Sumthong P., Damveld R.A., Choi Y.H., Arentshorst M., Ram A.F.J., Hondel C.A.M.J.J. van den & Verpoorte R. (2006), Activity of quinones from teak (Tectona grandis) on fungal cell wall stress, Planta Medica 72: 943-944.artikel in tijdschrift (refereed)
  • Sumthong P., Damveld R.A., Choi Y.H., Arentshorst M., Ram A.F.J., Hondel C.A.M.J.J. van den & Verpoorte R. (2006), Activity of quinones from teak (Tectona grandis) on fungal cell wall stress, Planta Medica 72: 943-944.artikel in tijdschrift (refereed)
  • Biesebeke R. te, Boussier A., Biezen N. van, Braaksma M., Hondel C.A.M.J.J. van den, Vos W.M. de & Punt P.J. (2006), Expression of Aspergillus hemoglobin domain activities in Aspergillus oryzae grown on solid substrates improves growth rate and enzyme production, Biotechnology Journal 1: 822-827.artikel in tijdschrift (refereed)
  • Biesebeke R. te, Boussier A., Biezen N. van, Hondel C.A.M.J.J. van den & Punt P.J. (2006), Identification of secreted proteins of Aspergillus oryzae associated with growth on solid cereal substrates, Journal of Biotechnology 121: 482-485.artikel in tijdschrift (refereed)
  • Weenink X.O., Punt P.J., Hondel C.A.M.J.J. van den & Ram A.F.J. (2006), A new method for isolating hypersecretion mutants in Aspergillus niger, Applied microbiology and biotechnology 69: 711-717.artikel in tijdschrift (refereed)
  • Yuan X.L., Goosen C., Kools H., Maarel M.J., Hondel C.A.M.J.J. van den, Dijkhuizen L. & Ram A.F.J. (2006), Database mining and transcriptional analysis of genes encoding inulin-modifying enzymes of Aspergillus niger, Microbiology 152: 3061-3073.artikel in tijdschrift (refereed)
  • Michielse C.B., Hooykaas P.J.J., Hondel C.A.M.J.J. van den & Ram A.F.J. (2005), Agrobacterium-mediated transformation as a tool for functional genomics in fungi, Current Genetics 48: 1-17.artikel in tijdschrift
  • Vinck A., Terlou M., Pestman W.R., Martens E.P., Ram A.F.J., Hondel C.A.M.J.J. van den & Worsten H.A. (2005), Hyphal differentiation in the exploring mycelium of Aspergillus niger, Molecular Microbiology 58(3): 693-699.artikel in tijdschrift
  • Joosten V., Roelofs M.S., Dries N. van den, Goosen T., Verrips C.T., Hondel C.A.M.J.J. van den & Lokman B.C. (2005), Production of bifunctional proteins by Aspergillus awamori: llama variable heavy chain antibody fragment (V(HH)) R9 coupled to Arthromyces ramosus peroxidase (ARP), Journal of Biotechnology 120(4): 347-359.artikel in tijdschrift
  • Damveld R.A., Arentshorst M., Kuyk P.A. van, Klis F.M., Hondel C.A.M.J.J. van den & Ram A.F.J. (2005), The Aspergillus niger MADS-box transcription factor RlmA is required for cell wall reinforcement in response to cell wall stress, Molecular Microbiology 58(1): 305-319.artikel in tijdschrift
  • Damveld R.A., Arentshorst M., Kuyk P.A. van, Klis F.M., Hondel C.A.M.J.J. van den & Ram A.F.J. (2005), Characterisation of CwpA, a putative glycosylphosphatidylinositol-anchored cell wall mannoprotein in the filamentous fungus Aspergillus niger, Fungal genetics and biology 42(10): 873-885.artikel in tijdschrift
  • Biesebeke R. te, Record E., Biezen N. van, Heerikhuisen M., Punt P.J. & Hondel C.A.M.J.J. van den (2005), Branching mutants of Aspergillus oryzae with improved amylase and protease production on solid substrates, Applied microbiology and biotechnology 69(1): 44-50.artikel in tijdschrift
  • Biesebeke R. te, Biezen N. van, Vos V.M. de, Hondel C.A.M.J.J. van den & Punt P.J. (2005), Different control mechanisms regulate glucoamylase and protease gene transcription in Aspergillus oryzae in solid-state and submerged fermentation, Applied microbiology and biotechnology 67(1): 75-82.artikel in tijdschrift
  • Damveld R.A., Kuyk P.A. van, Arentshorst M., Klis F.M., Hondel C.A.M.J.J. van den & Ram A.F.J. (2005), Expression of agsA, one of five 1,3-alpha-D-glucan synthase-encoding genes in Aspergillus niger, is induced in response to cell wall stress, Fungal genetics and biology 42(5): 165-177.artikel in tijdschrift
  • Michielse C.B., Arentshorst M., Ram A.F.J. & Hondel C.A.M.J.J. van den (2005), Agrobacterium-mediated transformation leads to improved gene replacement efficiency in Aspergillus awamori, Fungal genetics and biology 42(1): 9-19.artikel in tijdschrift
  • Michielse C.B., Ram A.F.J., Hooykaas P.J.J. & Hondel C.A.M.J.J. van den (2004), Role of bacterial virulence proteins in Agrobacterium-mediated transformation of Aspergillus awamori, Fungal genetics and biology 41: 571-578.artikel in tijdschrift (refereed)
  • Michielse C.B., Ram A.F.J., Hooykaas P.J.J. & Hondel C.A.M.J.J. van den (2004), Agrobacterium-mediated transformation of Aspergillus awamori in the absence of full-length VirD2, VirC2, or VirE2 leads to insertion of aberrant T-DNA structures, Journal of Bacteriology 186: 2038-2045.artikel in tijdschrift (refereed)
  • Michielse C.B., Salim K., Ragas P., Ram A.F.J., Kudla B., Jarry B., Punt P.J. & Hondel C.A.M.J.J. van den (2004), Development of a system for integrative and stable transformation of the zygomycete Rhizopus oryzea by Agrobacterium-mediated DNS transfer, Molecular Genet. Genomics 271: 499-510.artikel in tijdschrift (refereed)
  • Michielse C.B., Ram A.F.J. & Hondel C.A.M.J.J. van den (2004), The Aspergillus nidulans amdS gene as a marker for the identification of multicopy T-DNA integration events in Agrobacterium-mediated transformation of Aspergillus awamori, Current Genetics 45: 399-403.artikel in tijdschrift (refereed)
  • Michielse C.B., Ram A.F.J., Hooykaas P.J.J. & Hondel C.A.M.J.J. van den (2004), Agrobacterium-mediated transformation of Aspergillus awamori in the absence of full-length VirD2, VirC2, or VirE2 leads to insertion of aberrant T-DNA structures, Journal of Bacteriology 186: 2038-2045.artikel in tijdschrift (refereed)
  • Nelson G., Kozlova-Zwinderman O., Collis A.J., Knight M.R., Fincham J.R., Stanger C.P., Renwick A., Hessing J.G., Punt P.J., Hondel C.A.M.J.J. van den & Read N.D. (2004), Calcium measurement in living filamentous fungi expressing codon-optimized aequorin, Molecular Microbiology 52: 1437-1450.artikel in tijdschrift (refereed)
  • Ram A.F.J., Arentshorst M., Damveld R.A., Kuyk P.A. van, Klis F.M. & Hondel C.A.M.J.J. van den (2004), The cell wall stress response in Aspergillus niger involves increased expression of the glutamine:fructose-6-phosphate amidotransferase-encoding gene (gfaA) and increased deposition of chitin in the cell wall, Microbiology 150: 3315-3326.artikel in tijdschrift (refereed)
  • Sigoillot C., Record E., Belle V., Robert J.L., Levasseur A., Punt P.J., Hondel C.A.M.J.J. van den, Fournel A., Sigoillot J.C. & Asther M. (2004), Natural and recombinant fungal laccases for paper pulp bleaching, Applied microbiology and biotechnology 62: 349-355.artikel in tijdschrift (refereed)
  • Joosten V., Lokman C., Hondel C.A.M.J.J. van den & Punt P.J. (2003), The production of antibody fragments and antibody fusion proteins by yeasts and filamentous fungi, Microb. Cell Fact. 2(1): 1-15.artikel in tijdschrift (refereed)
  • Lokman B.C., Joosten V., Hovenkamp J., Gouka R.J., Verrips C.T. & Hondel C.A.M.J.J. van den (2003), Efficient production of Arthromyces ramosus peroxidase by Aspergillus awamori, Journal of Biotechnology 103(2): 183-190.artikel in tijdschrift (refereed)
  • Lokman B.C., Joosten V., Gouka R.J., Verrips C.T. & Hondel C.A.M.J.J. van den (2003), Production of Arthromyces ramoses peroxidase by three eukaryotic expression hosts: Aspergillus awamori is the preferred host compared to Saccharomyces cerevisiae and Pichia pastoris, Yeast 20: S310-S310.artikel in tijdschrift (refereed)
  • Punt P.J., Drint-Kuijvenhoven A., Lokman B.C., Spencer J.A., Jeenes D.J., Archer D.A. & Hondel C.A.M.J.J. van den (2003), The role of the Aspergillus niger furin-type protease gene in processing of fungal proproteins and fusion proteins. Evidence for alternative processing of recombinant (fusion-) proteins, Journal of Biotechnology 106(1): 23-32.artikel in tijdschrift (refereed)
  • Record E., Asther M., Sigoillot C., Pages S., Punt P.J., Delattre M., Haon M., Hondel C.A.M.J.J. van den, Sigoillot J.C. & Lesage-Meesen L. (2003), Overproduction of the Aspergillus niger feruloyl esterase for pulp bleaching application, Applied microbiology and biotechnology 62: 349-355.artikel in tijdschrift (refereed)
  • Ahman J., Johansson T., Olsson M., Punt P.J., Hondel C.A.M.J.J. van den & Tunlid A. (2002), Improving the pathogenicity of a nematode-trapping fungus by genetic engineering of a subtilisin with nematotoxic activity, Applied and Environmental Microbiology 68(7): 3408-3415.artikel in tijdschrift (refereed)
  • Biesebeke R. te, Ruiter G., Rahardjo Y.S.P., Hoogschagen M.J., Heerikhuisen M., Levin A., Driel K.G.A. van, Schutyser M.A.I., Dijksterhuis J., Zhu Y., Weber F.J., Vos W.M. de, Hondel C.A.M.J.J. van den, Rinzema A. & Punt P.J. (2002), Aspergillus oryzae in solid-state and submerged fermentations progress report on a multi-disciplinary project, FEMS Yeast Research 2: 245-248.artikel in tijdschrift (refereed)
  • Conesa A., Punt P.J. & Hondel C.A.M.J.J. van den (2002), Fungal peroxidases: molecular aspects and applications, Journal of Biotechnology 93(2): 143-158.artikel in tijdschrift (refereed)
  • Lagopodi A., Ram A.F.J., Lamers G.E.M., Punt P.J., Hondel C.A.M.J.J. van den, Lugtenberg E.J.J. & Bloemberg G.V. (2002), Novel aspects of tomato root colonization and infection by Fusarium oxysporum f. sp. radicislycopersici revealed by confocal laser scanning microscopic analysis using the green fluorescent protein as a marker, Molecular Plant Microbe Interactions 15(2): 172-179.artikel in tijdschrift (refereed)
  • Conesa A., Jeenes D.J., Archer D.B., Hondel C.A.M.J.J. van den & Punt P.J. (2002), Calnexin overexpression increases manganese peroxidase production in Aspergillus niger, Applied and Environmental Microbiology 68(2): 846-851.artikel in tijdschrift (refereed)
  • Punt P.J., Biezen N. van, Conesa A., Albers A., Mangnus J. & Hondel C.A.M.J.J. van den (2002), Filamentous fungi as cell factories for heterologous protein production, Trends Biotechnol. 20(5): 200-206.artikel in tijdschrift (refereed)
  • Record E., Punt P.J., Chamkha M., Labat M., Hondel C.A.M.J.J. van den & Asther M. (2002), Expression of the Pycnoporus cinnabarinus laccase gene in Aspergillus niger and characterization of the recombinant enzyme, European Journal of Biochemistry 269: 602-609.artikel in tijdschrift (refereed)
  • Lagopodi A., Ram A.F.J., Lamers G.E.M., Punt P.J., Hondel C.A.M.J.J. van den, Lugtenberg B.J.J. & Bloemberg G.V. (2002), Confocal laser scanning microsopical analysis of tomato root colonization and inffection by Fusarium oxysporum f.sp. radicis-lycopersici using the green fluorescent protein as a marker, Molecular Plant Microbe Interactions 15: 172-179.artikel in tijdschrift (refereed)
  • Siedenberg D., Mestric S., Ganzlin M., Schmidt M., Punt P.J., Hondel C.A.M.J.J. van den & Rinas U. (1999), GlaA promoter controlled production of a mutant green fluorescent protein (S65T) by recombinant A. niger during growth on defined medium in batch and fed-batch cultures, Biotech. Prog. 15: 43-50.artikel in tijdschrift (refereed)
  • Santerre Henriksen A.L., Even S., Müller C., Punt P.J., Hondel C.A.M.J.J. van den & Nielsen J. (1999), Study of the glucoamylase promoter in Aspergillus niger using green fluorescent protein, Microbiology UK 145: 729-734.artikel in tijdschrift (refereed)
  • Ngiam C., Jeenes D.J., Punt P.J., Hondel C.A.M.J.J. van den & Archer D.B. (1999), Characterisation of a foldase, PDIA, in the protein secretory pathway of Aspergillus niger, Applied Environmental Microbiology 66: 775-782.artikel in tijdschrift (refereed)
  • Maras M., Die I. van, Contreras R. & Hondel C.A.M.J.J. van den (1999), Filamentous fungi as production organisms for glycoproteins of bio-medical interest, Glycoconjugate Journal 16: 99-107.artikel in tijdschrift (refereed)
  • Hitexacoat Voorzitter
  • Stichting Microbiol and Biotechnological Consultancy Consultant
  • Stichting European Conference of Fungal Genetics Voorzitter