Johan Kuiper
Hoogleraar Therapeutische immunomodulatie
- Naam
- Prof.dr. J. Kuiper
- Telefoon
- +31 71 527 4378
- j.kuiper@lacdr.leidenuniv.nl
Meer informatie is beschikbaar op de Engelse profielpagina.
Meer informatie over Johan Kuiper
Nieuws
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Slagaderverkalking lijkt op een auto-immuunziekte. Marie Depuydt promoveerde er cum laude op -
Het immuunsysteem beïnvloeden met nanobolletjes -
Johan Kuiper en Ilze Bot geportretteerd op Hartstichting.nl -
Verschillen tussen mannen en vrouwen bij slagaderverkalking -
Ontwikkelen van een vaccin tegen aderverkalking
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Aderverkalking: vetten en ontstekingsreacties aanpakken
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De onverwachte rol van IL-27 bij aderverkalking
Oud-promovendi
Meer informatie is beschikbaar op de Engelse profielpagina.
Hoogleraar Therapeutische immunomodulatie
- Wiskunde en Natuurwetenschappen
- Leiden Academic Centre for Drug Research
- LACDR/Biopharmaceutics
- Jong M.J.M. de, Schaftenaar F.H., Depuydt M.A.C., Lozano Vigario F., Janssen G.M.C., Peeters J.A.H.M., Goncalves L., Wezel A., Smeets H.J., Kuiper J., Bot I., Veelen P. van & Slütter B.A. (2024), Virus-associated CD8+T-cells are not activated through antigen-mediated interaction inside atherosclerotic lesions, Arteriosclerosis, Thrombosis, and Vascular Biology : 1-13.
- Mulholland M., Depuydt M.A.C., Jakobsson G., Ljungcrantz I., Grentzmann A., To F., Bengtsson E., Jaensson Gyllenbäck E., Grönberg C., Rattik S., Liberg D., Schiopu A., Björkbacka H., Kuiper J., Bot I., Slütter B.A. & Engelbertsen D. (2024), Interleukin-1 receptor accessory protein blockade limits the development of atherosclerosis and reduces plaque inflammation, Cardiovascular Research : cvae046.
- Delfos L., Depuydt M.A.C., Foks A.C., Bernabe Kleijn M.N.A., Kuiper J., Chemaly M., Peace A., McGilligan V. & Bot I. (2023), NLRP3 inflammasome inhibition by the novel bispecific antibody inflamab inhibits atherosclerosis in apolipoprotein E-deficient mice, Atherosclerosis 379(Supplement 1): S2.
- Smit V., Mol J. de, Schaftenaar F.H., Depuydt M.A.C., Postel R.J., Smeets D.: Verheijen F.W.M., Bogers L., Duijn J. van, Verwilligen R.A.F., Grievink H.W., Bernabé Kleijn M.N.A., Ingen E. van, Jong M.J.M. de, Goncalves L.: Peeters J.A.H.M., Smeets H.J., Wezel A., Polansky J.K., Winther M.P.J. de, Binder C.J., Tsiantoulas D., Bot I., Kuiper J. & Foks A.C. (2023), Single-cell profiling reveals age-associated immunity in atherosclerosis, Cardiovascular Research 119(15): 2508-2521.
- Depuydt M.A.C., Schaftenaar F.H., Prange H.H.M., Boltjes A., Hemme E., Delfos L., Mol J. de, Jong M.J.M. de, Bernabé Kleijn M.N.A., Peeters J.A.H.M., Goncalves L., Wezel A., Smeets H.J., Borst G.J. de, Foks A.C., Pasterkamp G., Winther M.P.J. de, Kuiper J., Bot I. & Slütter B. (2023), Single-cell T cell receptor sequencing of paired human atherosclerotic plaques and blood reveals autoimmune-like features of expanded effector T cells, Nature Cardiovascular Research 2: 112-125.
- Hemme E.: Biskop D., Depuydt M.A.C., Smit V., Delfos L., Bernabé Kleijn M.N.A., Foks A.C., Kuiper J. & Bot I. (2023), Bruton's Tyrosine Kinase inhibition by Acalabrutinib does not affect early or advanced atherosclerotic plaque size and morphology in Ldlr-/- mice, Vascular Pharmacology 150: 107172.
- Hemme E., Depuydt M.A.C., Delfos L., Kuiper J. & Bot I. (2023), Leukemia inhibitory factor receptor inhibition in atherosclerosis, Atherosclerosis 379: S36.
- Depuydt M.A.C., Vlaswinkel F.D., Hemme E., Delfos L., Bernabe Kleijn M.N.A., Santbrink P.J. van, Foks A.C., Slütter B., Kuiper J. & Bot I. (2022), Blockade of the BLT1-LTB4 axis does not affect mast cell migration towards advanced atherosclerotic lesions in LDLr-/- mice, Scientific Reports 12(1): 18362.
- Grievink H.W., Smit V., Huisman B.W., Gal P., Yavuz Y., Klerks C., Binder C.J., Bot I., Kuiper J., Foks A.C. & Moerland M. (2022), Cardiovascular risk factors: the effects of ageing and smoking on the immune system, an observational clinical study, Frontiers in immunology 13: 968815.
- Depuydt M.A.C., Smit V., Lozano Vigario F., Bernabé Kleijn M.N.A., Vries M.R. de, Quax P.H.A., Wezel A., Smeets H.J., Kuiper J., Foks A.C., Bot I. & Slütter B.A. (2022), Granzyme B+CD4+T cells associate with an unstable plaque phenotype in advanced human atherosclerosis, Cardiovascular Research 118(Supplement_1): cvac066.229.
- Mol J. de, Postel R.J., Smit V., Bernabé Kleijn M.N.A., Bot I., Kuiper J. & Foks A.C. (2022), B cell depletion skews cd4+t cell towards a pro-inflammatory phenotype in aged atherosclerotic mice, Cardiovascular Research 118(Supplement_1): cvac066.230.
- Douna H., Mol J. de, Amersfoort J., Schaftenaar F.H., Kiss M.G., Suur B.E., Kroner M.J., Binder C.J., Bot I., Puijvelde G.H.M. van, Kuiper J. & Foks A.C. (2022), IFNγ-stimulated B cells inhibit T follicular helper cells and protect against atherosclerosis, Frontiers in Cardiovascular Medicine 9: 781436.
- Hemme E., Delfos L., Depuydt M.A.C., Bernabé Kleijn M.N.A., Schaftenaar F.H., Foks A.C., Kuiper J. & Bot I. (2022), Brutons tyrosine kinase inhibition to suppress mast cell activation in atherosclerosis, Cardiovascular Research 118(Supplement_1): cvac066.227.
- Douna H., Smit V., Puijvelde G.H.M. van, Kiss M.G., Binder C.J., Bot I., Kuchroo V.K., Lichtman A.H., Kuiper J. & Foks A.C. (2022), Tim-1 mucin domain-mutant mice display exacerbated atherosclerosis, Atherosclerosis 352: 1-9.
- Postel R.J., Smit V., De Mol J., Bernabé Kleijn M.N.A., De Jong M.J.M., Delfos L., Hemme E., Depuydt M.A.C., Bot I., Kuiper J. & Foks A.C. (2022), IL-21R blockade reduces atherosclerosis development in LDLR-/- mice, Atherosclerosis 355: 23.
- Grievink H.W., Smit V., Verwilligen R.A.F., Bernabé Kleijn M.N.A., Smeets D., Binder C.J., Yagita H., Moerland M., Kuiper J., Bot I. & Foks A.C. (2021), Stimulation of the PD-1 pathway decreases atherosclerotic lesion development in Ldlr deficient mice, Frontiers in Cardiovascular Medicine 8: 740531.
- Slenders L., Landsmeer L.P.L., Cui K., Depuydt M.A.C., Verwer M., Mekke J., Timmerman N., Dungen N.A.M. van den, Kuiper J., Winther M.P.J. de Prange K.H.M., Ma W.F., Miller C.L., Aherrahrou R., Civelek M., Borst G.J. de, Kleijn D.P.V. de, Asselbergs F.W., Ruijter H.M. den, Boltjes A, Pasterkamp G. & Laan S.W. van den Mokry M. (2021), Intersecting single-cell transcriptomics and genome-wide association studies identifies crucial cell populations and candidate genes for atherosclerosis, European Heart Journal Open 2(1): oeab043.
- Reilly N.A., Lutgens E., Kuiper J., Heijmans B.T. & Jukema J.W. (2021), Effects of fatty acids on T cell function: role in atherosclerosis, Nature Reviews Cardiology : .
- Duijn J. van, Jong M.J.M. de, Benne N., Leboux R.J.T., Ooijen M.E. van, Kruit N., Foks A.C., Jiskoot W., Bot I., Kuiper J. & Slütter B. (2021), Tc17 CD8+ T-cells accumulate in murine atherosclerotic lesions, but do not contribute to early atherosclerosis development, Cardiovascular Research 117(14): 2755-2766.
- Amersfoort J., Schaftenaar F.H., Douna H., Santbrink P.J. van, Puijvelde G.H.M. van, Slütter B., Foks A.C., Harms A., Moreno-Gordaliza E., Wang Y., Hankemeier T., Bot I., Chi H. & Kuiper J. (2021), Diet-induced dyslipidemia induces metabolic and migratory adaptations in regulatory T cells, Cardiovascular Research 117(5): 1309-1324.
- Vries M.R. de, Ewing M.M., Jong R.C.M. de, MacArthur M.R., Karper J.C., Peters E.A.B., Nordzell M., Karabina S.A.P., Sexton D., Dahlbom I., Bergman A., Mitchell J.R., Frostegård J., Kuiper J., Ninio E., Wouter Jukema J., Pettersson K. & Quax P.H.A. (2021), Identification of IgG1 isotype phosphorylcholine antibodies for the treatment of inflammatory cardiovascular diseases, Journal of Internal Medicine 290(1): 141-156.
- Mekke J.M., Egberts D.H.J., Waissi F., Timmerman N., Bot I., Kuiper J., Pasterkamp G., Borst G.J. de & Kleijn D.P.V. de (2021), Mast cell distribution in human carotid atherosclerotic plaque differs significantly by histological segment, European Journal of Vascular and Endovascular Surgery 62(5): 808-815.
- Mol J. de, Kuiper J., Tsiantoulas D. & Foks A.C. (2021), The dynamics of B cell aging in health and disease, Frontiers in Immunology 12: 733566.
- Benne N., Martins Cardoso R., Boyle A.L., Kros A., Jiskoot W., Kuiper J., Bouwstra J., Eck M. van & Slütter B.A. (2020), Complement Receptor Targeted Liposomes Encapsulating the Liver X Receptor Agonist GW3965 Accumulate in and Stabilize Atherosclerotic Plaques, Advanced Healthcare Materials 9(10): 2000043.
- Bot I., Velden D. van der, Bouwman M., Kröner M.J., Kuiper J., Quax P.H.A. & Vries M.R. de (2020), Local Mast Cell Activation Promotes Neovascularization, Cells 9(3): 701.
- Douna H., Amersfoort J., Schaftenaar F.H., Kröner M.J., Kiss M.B., Slütter B.A., Depuydt M.A.C., Bernabé Kleijn M.N.A., Wezel A., Smeets H., Yagita H., Binder C.J., Bot I., Puijvelde G.H.M. van, Kuiper J. & Foks A.C. (2020), BTLA stimulation protects against atherosclerosis by regulating follicular B cells, Cardiovascular Research 116(2): 295-305.
- Lozano Vigario F. Kuiper J. Slütter B.A. (2020), Tolerogenic vaccines for the treatment of cardiovascular diseases, EBioMedicine 57: 102827.
- Depuydt M.A.C., Prange K.H.M., Slenders L., Örd T., Elbersen D., Boltjes A., Jager S.C.A. de, Asselbergs F.W., Borst G.J. de, Aavik E., Lönnberg T., Lutgens E., Glass C.K., Ruijter H.M. den, Kaikkonen M.U., Bot I., Slütter B., Laan S.W. van der, Yla-Herttuala S., Mokry M., Kuiper J., Winther M.P.J. de & Pasterkamp G. (2020), Microanatomy of the human atherosclerotic plaque by single-cell transcriptomics, Circulation Research 127(11): 1437-1455.
- Grievink H.W., Gal P., Ozsvar Kozma M., Klaassen E.S., Kuiper J., Burggraaf J., Binder C.J. & Moerland M. (2020), The effect of a 13-valent conjugate pneumococcal vaccine on circulating antibodies against oxidized LDL and phosphorylcholine in man: a randomized placebo-controlled clinical trial, Biology 9(11): 345.
- Benne N., Leboux R.J.T., Glandrup M., Duijn J. van, Lozano Vigario F., Neustrup M.A., Romeijn S., Galli F., Kuiper J., Jiskoot W. & Slütter B. (2019), Atomic force microscopy measurements of anionic liposomes reveal the effect of liposomal rigidity on antigen-specific regulatory T cell responses, Journal of Controlled Release 318: 246-255.
- Depuydt M., Prange K.H.M., Slenders L., Elbersen D., Boltjes A., De Jager S.C.A., Slutter B.A., Bot I., Laan S.W. van der, Mokry M., Pasterkamp G., Winther M.P.J. de & Kuiper J. (2019), Microanatomy of advanced human atherosclerotic plaques through single-cell transcriptomics, Atherosclerosis 287: E5-E5.
- Laan S.W. van der, Slenders L., Depuydt M., Prange K., Granneman L., Elbersen D., Boltjes A., Jager S. de, Slutter B., Bot I., Winther M., Kuiper J., Mokry M., Asselbergs F. & Pasterkamp G. (2019), Mapping genes to cardiovascular susceptibility loci at a single-cell resolution, Atherosclerosis 287: E21-E21.
- Duijn J. van, Elsas M. van, Benne N., Depuydt M., Wezel A., Smeets H., Bot I., Jiskoot W., Kuiper J. & Slutter B. (2019), Continuous Tcr signaling in the atherosclerotic environment induces immunomodulatory Cd8+ T-cells expressing Cd39, Atherosclerosis 287: e17-e18.
- Korporaal S.J.A., Molenaar T.J.M., Lutters B.C.H., Meurs I., Drost-Verhoef S., Kuiper J., Berkel T.J.C. van & Biessen E.A.L. (2019), Peptide Antagonists for P-selectin Discriminate between Sulfatide-Dependent Platelet Aggregation and PSGL-1-Mediated Cell Adhesion, Journal of Clinical Medicine 8(8): 1266.
- Roscam Abbing R.L.P., Slijepcevic D., Donkers J.M., Havinga R., Duijst S., Paulusma C.C., Kuiper J., Kuipers F., Groen A.K., Oude Elferink R.P.J. & Graaf S.F.J. van de (2019), Blocking Sodium-Taurocholate Cotransporting Polypeptide Stimulates Biliary Cholesterol and Phospholipid Secretion in Mice, Hepatology 71(1): 247-258.
- Duijn J. van, Elsas M. van, Benne N., Depuydt M.A.C., Wezel A., Smeets H., Bot I., Jiskoot W., Kuiper J. & Slütter B.A. (2019), CD39 identifies a microenvironment-specific anti-inflammatory CD8+ T-cell population in atherosclerotic lesions, Atherosclerosis 285: 71-78.
- Douna H., Amersfoort J., Schaftenaar F.H., Kroon S., Puijvelde G.H.M. van, Kuiper J. & Foks A.C. (2019), Bidirectional effects of IL-10+ regulatory B cells in Ldlr−/− mice, Atherosclerosis 280: 118-125.
- Heijden T. van der, Bot I. & Kuiper J. (2019), The IL-12 cytokine family in cardiovascular diseases, Cytokine 122: 154188.
- Meeuwsen J.A.L., Vries J.J. de, Duijvenvoorde A. van, Velden S. van der, Laan S.W. van der, Koeverden I.D. van, Weg S.M. van de, Borst G.J. de, Winther M.J.P. de, Kuiper J., Pasterkamp G., Hoefer I.E. & Jager S.C.A. de (2019), Circulating CD14+CD16− classical monocytes do not associate with a vulnerable plaque phenotype, and do not predict secondary events in severe atherosclerotic patients, Journal of Molecular and Cellular Cardiology 127: 260-269.
- Lagraauw H.M., Wezel A., Velden D. van der, Kuiper J. & Bot I. (2019), Stress-induced mast cell activation contributes to atherosclerotic plaque destabilization, Scientific Reports 9(1): 2134.
- Kritikou E., Depuydt M.A.C., Vries M.R. de, Mulder K.E., Govaert A.M., Smit M.D., Duijn J. van, Foks A.C., Wezel A., Smeets H.J., Slütter B., Quax P.H.A., Kuiper J. & Bot I. (2019), Flow Cytometry-Based Characterization of Mast Cells in Human Atherosclerosis, Cells 8(4): 334.
- Slütter B. & Kuiper J. (2019), Immune Responses in Context, Circulation 139(22): 2567-2569.
- Benne N., Duijn J. van, Lozano Vigario F., Leboux R., Veelen P. van, Jiskoot W., Kuiper J. & Slütter B. (2019), Vaccination with a regulatory t-cell inducing vaccine formulation containing apob100 peptides, reduces atherosclerosis in mice, Atherosclerosis 287: e99-e100.
- Douna H., Amersfoort J., Schaftenaar F.H., Kröner M.J., Kiss M.B., Slütter B., Depuydt M.A.C., Kleijn M.N.A.B., Wezel A., Smeets H., Yagita H., Binder C.J., Bot I., Puijvelde G.H.M. van, Kuiper J. & Foks A.C. (2019), B- and T-lymphocyte attenuator stimulation protects against atherosclerosis by regulating follicular B cells, Cardiovascular Research 116(2): 295-305.
- Douna H., Smit V., Puijvelde G. van, Binder C., Bot I., Kuchroo V., Lichtman A., Kuiper J. & Foks A. (2019), Tim-1 mucin domain-mutant mice display exacerbated atherosclerosis, Atherosclerosis 287: E25-E26.
- Mokry M., Depuydt M.A.C., Prange K.H.M., Slenders L., Elbersen D., Granneman L.E.C., Jager S.C.A. de, Slutter B.A., Bot I., Winther M.P.J. de, Kuiper J., Asselbergs F.W., Laan S.W. van der & Pasterkamp G. (2019), Single cell Rna-sequencing identifies numerous cell sub-types and suggests lineage plasticity in human atherosclerotic plaques, Atherosclerosis 287: E96-E97.
- Ingen E. van, Foks A.C., Kröner M.J., Kuiper J., Quax P.H.A., Bot I. & Nossent Y. (2019), Inhibition Of Microrna-494 Halts Atherosclerotic Plaque Progression And Stabilizes Advanced Atherosclerotic Lesions, Atherosclerosis 287: E15.
- Kritikou E., Heijden T. van der, Swart M., Duijn J. van, Slütter B., Wezel A., Smeets H.J., Maffia P., Kuiper J. & Bot I. (2019), Hypercholesterolemia induces a mast cell-CD4+ T cell interaction in atherosclerosis, Journal of Immunology 202(5): 1531-1539.
- Schaftenaar F.H., Amersfoort J., Douna H., Kröner M.J., Foks A.C., Bot I., Slütter B.A., Puijvelde G.H.M. van, Drijfhout J.W. & Kuiper J. (2019), Induction of HLA-A2 restricted CD8 T cell responses against ApoB100 peptides does not affect atherosclerosis in a humanized mouse model, Scientific Reports 9(1): 17391.
- Ingen E. van, Foks A.C., Kröner M.J., Kuiper J., Quax P.H.A., Bot I. & Nossent A.Y. (2019), Antisense Oligonucleotide Inhibition of MicroRNA-494 Halts Atherosclerotic Plaque Progression and Promotes Plaque Stabilization, Molecular Therapy - Nucleic Acids 18: 638-649.
- Amersfoort J., Kuiper J. & Bot I. (2018), Reply to "Lipocalin-2 contributes to experimental atherosclerosis in a stage-dependent manner", Atherosclerosis 278: 323-324.
- Duijn J. van, Kuiper J. & Slütter B.A. (2018), The many faces of CD8+ T cells in atherosclerosis, Current Opinion in Lipidology 29(5): 411-416.
- Ingen E. van, Foks A.C., Kröner M.J., Agrawal S., Kuiper J., Quax P.H.A., Bot I. & Nossent A.Y. (2018), Inhibition of microRNA-494 halts atherosclerotic plaque progression and stabilizes advanced atherosclerotic lesions, Cardiovascular Research 114(suppl_1): S57-S57.
- Slütter B.A., Depuydt M.A.C., Duijn J. van, Bot I., Wezel A., Koppejan H., Toes R. & Kuiper J. (2018), Masscytometry identifies CD8 T-cell diversity in human atherosclerotic lesions, Atherosclerosis 275: e8.
- Seijkens T.T.P., Poels K., Meiler S., Tiel C.M. van, Kusters P.J.H., Reiche M., Atzler D., Winkels H., Tjwa M., Poelman H., Slütter B., Kuiper J., Gijbels M., Kuivenhoven J.A., Matic L.P., Hedin U., Paulsson-Berne G., Nicolaes G.A.F., Hansson G.K., Weber C., Daemen M.J.A.P., Winther M.P.J. de, Gerdes N. & Lutgens E. (2018), Deficiency of the T cell regulator Casitas B-cell lymphoma-B aggravates atherosclerosis by inducing CD8+ T cell-mediated macrophage death, European Heart Journal 40(4): 372-382.
- Amersfoort J., Douna H., Schaftenaar F.H., Foks A.C., Kröner M.J., Santbrink P.J. van, Puijvelde G.H.M. van, Bot I. & Kuiper J. (2018), Defective Autophagy in T Cells Impairs the Development of Diet-Induced Hepatic Steatosis and Atherosclerosis, Frontiers in Immunology 9: 2937.
- Benne N., Duijn J. van, Lozano Vigario F.L., Leboux R.J.T., Veelen P. van, Kuiper J., Jiskoot W. & Slütter B. (2018), Anionic 1,2-distearoyl-sn-glycero-3-phosphoglycerol (DSPG) liposomes induce antigen-specific regulatory T cells and prevent atherosclerosis in mice, Journal of Controlled Release 291: 135-146.
- Duijn J. van, Kritikou E., Benne N., Heijden T. van der, Puijvelde G.H. van, Kröner M.J., Schaftenaar F.H., Foks A.C., Wezel A., Smeets H., Yagita H., Bot I., Jiskoot W., Kuiper J. & Slütter B. (2018), CD8+ T-cells contribute to lesion stabilization in advanced atherosclerosis by limiting macrophage content and CD4+ T-cell responses, Cardiovascular Research 115(4): 729-738.
- Seijkens T.T.P., Tiel C.M. van, Kusters P.J.H., Atzler D., Soehnlein O., Zarzycka B., Aarts S.A.B.M., Lameijer M., Gijbels M.J., Beckers L., Toom M. den, Slütter B.A., Kuiper J., Duchene J., Aslani M., Megens R.T.A., Veer C. van 't, Kooij G., Schrijver R., Hoeksema M.A., Boon L., Fay F., Tang J., Baxter S., Jongejan A., Moerland P.D., Vriend G., Bleijlevens B., Fisher E.A., Duivenvoorden R., Gerdes N., Winther M.P.J. de, Nicolaes G.A., Mulder W.J.M., Weber C. & Lutgens E. (2018), Targeting CD40-Induced TRAF6 Signaling in Macrophages Reduces Atherosclerosis, Journal of the American College of Cardiology 71(5): 527-542.
- Puijvelde G.H.M. van, Foks A.C., Bochove R.E. van, Bot I., Habets K.L.L., Jager S.C. de, Borg M.N.D. ter, Osch P. van, Boon L., Vos M., Waard V. de & Kuiper J. (2018), CD1d deficiency inhibits the development of abdominal aortic aneurysms in LDL receptor deficient mice, Plos One 13(1): e0190962.
- Amersfoort J., Schaftenaar F.H., Douna H., Santbrink P.J. van, Kröner M.J., Puijvelde G.H.M. van, Quax P.H.A., Kuiper J. & Bot I. (2018), Lipocalin-2 contributes to experimental atherosclerosis in a stage-dependent manner, Atherosclerosis 275: 214-224.
- Kritikou E., Duijn J. van, Nahon J.E., Heijden T. van der, Bouwman M., Groeneveldt C., Schaftenaar F.H., Kröner M.J., Kuiper J., Puijvelde G.H.M. van & Bot I. (2018), Disruption of a CD1d-mediated interaction between mast cells and NKT cells aggravates atherosclerosis, Atherosclerosis 280: 132-139.
- Schaftenaar F.H., Amersfoort J., Douna H., Kroner M.J., Slutter B.A., Bot I., Puijvelde G.H.M. van & Kuiper J. (2018), Vaccination with APOB100 derived HLA-A2 restricted CD8 T cell epitopes did not reduce atherosclerosis in male LDLRKO HAPOB100TG HLA-A2TG mice, Atherosclerosis Supplements 32: 100-101.
- Douna H., Amersfoort J., Schaftenaar F.H., Puijvelde G.H.M. van, Kuiper J. & Foks A.C. (2018), Stimulation of the co-inhibitory BTLA pathway protects against atherosclerosis by selectively reducing atherogenic B cells, Atherosclerosis Supplements 32: 89-89.
- Even G., Kiss M., Laschet J., Ozvar Kozma M., Simon T., Wigren M., Gaston A., Procopio E., Le Borgne-Moynnier M., Nilsson J., Kuiper J., Nicoletti A., Binder C. & Caligiuri G. (2018), Vaccination with prevenar (R) boosts the production of anti-phosphorylcholine antibodies and protects apoe knockout mice from atherosclerosis, Atherosclerosis 275: E6-E7.
- Hermans M.P.J., Volkov M., Velden D. van der, Montero Cabezas J.M., Huizinga T.W.J., Kuiper J., Toes R.E.M., Schalij M.J., Jukema J.W. & Woude D. van der (2017), Anti-citrullinated protein antibodies: a marker of cardiovascular disease and mortality in patients without rheumatoid arthritis, Annals of the Rheumatic Diseases 76: A82-A82.
- Heijden T. van der, Kritikou E., Venema W., Duijn J. van, Santbrink P.J. van, Slütter B., Foks A.C., Bot I. & Kuiper J. (2017), NLRP3 Inflammasome Inhibition by MCC950 Reduces Atherosclerotic Lesion Development in Apolipoprotein E-Deficient Mice-Brief Report, Arteriosclerosis, Thrombosis, and Vascular Biology 37(8): 1457-1461.
- Bot I., Ortiz Zacarias N.V., Witte W.E. de, Vries H. de, Santbrink P.J. van, Velden D. van der, Kroener M.J., Berg D.J. van den, Stamos D., Lange E.C.M. de, Kuiper J., IJzerman A.P. & Heitman L.H. (2017), A novel CCR2 antagonist inhibits atherogenesis in apoE deficient mice by achieving high receptor occupancy, Scientific Reports 2017(7): 52.
- Ellenbroek G., Puijvelde G.H.M. van, Anas A.A., Bot M., Asbach M., Schoneveld A., Santbrink P.J. van, Foks A.C., Timmers L., Doevendans P.A., Pasterkamp G., Hoefer I.E., Poll T. van der, Kuiper J. & Jager S.C.A. de (2017), Leukocyte TLR5 deficiency inhibits atherosclerosis by reduced macrophage recruitment and defective T-cell responsiveness, Scientific Reports 7: 42688.
- Bot I. & Kuiper J. (2017), Stressed brain, stressed heart?, The Lancet 389(10071): 770-771.
- Amersfoort J. & Kuiper J. (2017), T cell metabolism in metabolic disease-associated autoimmunity, Immunobiology 222(10): 925-936.
- Hermans M.P.J., Velden D. van der, Montero Cabezas J.M., Putter H., Huizinga T.W.J., Kuiper J., Toes R.E.M., Schalij M.J., Jukema J.W. & Woude D. van der (2017), Long-term mortality in patients with ST-segment elevation myocardial infarction is associated with anti-citrullinated protein antibodies, International Journal of Cardiology 240: 20-24.
- Kritikou E., Heijden T. van der, Swart M., Duijn J. van, Slutter B., Smeets H., Maffia P., Kuiper J. & Bot I. (2017), Hypercholesterolemia induces a mast cell-CD4+ T-cell interaction in atherosclerosis, Atherosclerosis 263: E124-E124.
- Puijvelde G.H.M. van & Kuiper J. (2017), NKT cells in cardiovascular diseases, European Journal of Pharmacology 816: 47-57.
- Foks A.C. & Kuiper J. (2017), Immune checkpoint proteins: exploring their therapeutic potential to regulate atherosclerosis, British Journal of Pharmacology 174(22): 3940-3955.
- Montero-Cabezas J.M., Karalis I., Wolterbeek R., Kraaijeveld A.O., Hoefer I.E., Pasterkamp G., Pijls N.H., Doevendans P.A., Walterberger J., Kuiper J., Zonneveld A.J. van & Jukema J.W. (2017), Classical determinants of coronary artery disease as predictors of complexity of coronary lesions, assessed with the SYNTAX score, Netherlands Heart Journal 25(9): 490-497.
- Tsiantoulas D., Bot I., Ozsvar-Kozma M., Goederle L., Perkmann T., Hartvigsen K., Conrad D.H., Kuiper J., Mallat Z. & Binder C.J. (2017), Increased Plasma IgE Accelerate Atherosclerosis in Secreted IgM Deficiency, Circulation Research 120(1): 78-84.
- Woude D. van der, Hermans M.P., Velden D. van der, Trouw L.A., Huizinga T.W.J., Kuiper J., Schalij M.J., Jukema J.W. & Toes R.E. (2016), Anti-Citrullinated Protein Antibodies in Patients with Cardiovascular Disease without RA, Annals of the Rheumatic Diseases 75: 926-926.
- Hermans M., Velden D. van der, Huizinga T.W.J., Kuiper J., Toes R.E.M., Schalij M.J., Jukema J.W. & Woude D. van der (2016), Association Between Presence of a Cardiac Intensivist and Mortality in an Adult Cardiac Care Unit, Journal of the American College of Cardiology 67(13): 2322-2322.
- Moreno Gordaliza M.E., Lee S.J. van der, Demirkan A., Duijn C.M. van, Kuiper J., Lindenburg P.W. & Hankemeier T. (2016), A novel method for serum lipoprotein profiling using high performance capillary isotachophoresis, Analytica Chimica Acta 944: 57-69.
- Schaftenaar F., Frodermann V., Kuiper J. & Lutgens E. (2016), Atherosclerosis: the interplay between lipids and immune cells, Current Opinion in Lipidology 27(3): 209-215.
- Louwe M.C., Lammers B., Frias M.A., Foks A.C., Leeuw L.R. de., Hildebrand R.B., Kuiper J., Smit J.W.A., Berkel T.J.C. van, James R.W., Geerling J.J., Rensen P.C.N. & Eck M. van (2016), ABCA1 deficiency protects the heart against myocardial infarction-induced injury, Atherosclerosis 251: 159-163.
- Bot I. & Kuiper J. (2016), The origin of atherosclerotic plaque cells: Plasticity or not?, Atherosclerosis 251: 536-537.
- Kritikou E., Kuiper J., Kovanen P.T. & Bot I. (2016), The impact of mast cells on cardiovascular diseases, European Journal of Pharmacology 778: 103-115.
- Suurmond J., Velden D. van der, Kuiper J., Bot I. & Toes R.E. (2016), Mast cells in rheumatic disease, European Journal of Pharmacology 778: 116-124.
- Benne N., Jiskoot W., Kuiper J. & Slutter B.A. (2016), Stimulating antigen-specific regulatory T cells for an atherosclerosis vaccine, Journal of Immunology 196(1): 70.18.
- Douna H. & Kuiper J. (2016), Novel B-cell subsets in atherosclerosis, Current Opinion in Lipidology 27(5): 493-498.
- Tsiantoulas D., Bot I., Kiss M., Bartolini-Gritti B., Goederle L., Ozsvar-Kozma M., Perkmann T., Hartvigsen K., Bergthaler A., Conrad D.H., Kuiper J., Mallat Z., Jumaa H. & Binder C.J. (2016), Deficiency of secreted IgM antibodies causes increased plasma IgE levels that promote atherosclerosis, Atherosclerosis 252: E262-E263.
- Velden D. van der, Lagraauw H.M., Wezel A., Launay P., Kuiper J., Huizinga T.W.J., Toes R.E.M., Bot I. & Stoop J.N. (2016), Mast cell depletion in the preclinical phase of collagen-induced arthritis reduces clinical outcome by lowering the inflammatory cytokine profile, Arthritis Research & Therapy 18(1): 138.
- Benne N., Duijn J. van, Kuiper J., Jiskoot W. & Slütter B. (2016), Orchestrating immune responses: How size, shape and rigidity affect the immunogenicity of particulate vaccines, Journal of Controlled Release 234: 124-134.
- Foks A.C., Puijvelde G.H.M. van, Wolbert J., Kröner M.J., Frodermann V., Heijden T. van der, Santbrink P.J. van, Boon L., Bot I. & Kuiper J. (2016), CD11b+Gr-1+ myeloid-derived suppressor cells reduce atherosclerotic lesion development in LDLr deficient mice, Cardiovascular Research 111(3): 252-261.
- Frodermann V., Duijn J. van, Puijvelde G.H.M. van, Santbrink P.J. van, Lagraauw H.M., Vries M.R. de, Quax P.H.A., Bot I., Foks A.C., Jager S.C. de & Kuiper J. (2016), Heat-killed Staphylococcus aureus reduces atherosclerosis by inducing anti-inflammatory macrophages, Journal of Internal Medicine 279(6): 592-605.
- Bot I. & Kuiper J. (2016), Relaxing the artery: A new strategy to limit atherogenesis, Atherosclerosis 251: 510-511.
- Lagraauw H.M., Wezel A., Velden D. van der, Kuiper J. & Bot I. (2016), Stress-induced mast cell activation contributes to atherosclerotic plaque destabilization, Journal of Immunology 196(1 supplement): 197.4.
- Duijn J. van, Jiskoot W., Kuiper J. & Slutter B.A. (2016), A tissue-specific phenotype for CD8+T cells in atherosclerotic lesions: role of the arterial microenvironment, Journal of Immunology 196(1): 186.10.
- Kritikou E., Puijvelde G.H.M. van, Heijden T. van der, Santbrink P.J. van, Swart M., Schaftenaar F.H., Kroner M.J., Kuiper J. & Bot I. (2016), Inhibition of lysophosphatidic acid receptors 1 and 3 attenuates atherosclerosis development in LDL-receptor deficient mice, Scientific Reports 6: 37585.
- Wezel A., Vries M.R. de, Maassen J.M., Kip P., Peters E.A., Karper J.C., Kuiper J., Bot I. & Quax P.H.A. (2016), Deficiency of the TLR4 analogue RP105 aggravates vein graft disease by inducing a pro-inflammatory response, Scientific Reports 6: 24248.
- Wezel A., Velden D. van der, Maassen J.M., Lagraauw H.M., Vries M.R. de, Karper Ja., Kuiper J., Bot I. & Quax P.H.A. (2015), RP105 deficiency attenuates early atherosclerosis via decreased monocyte influx in a CCR2 dependent manner, Atherosclerosis 238(1): 132-139.
- Frodermann V., Duijn J. van, Pel M. van, Santbrink P.J. van, Bot I., Kuiper J. & Jager S.C. de (2015), Mesenchymal Stem Cells Reduce Murine Atherosclerosis Development, Scientific Reports 5: 15559.
- Foks A.C., Lichtman A.H. & Kuiper J. (2015), Treating atherosclerosis with regulatory T cells, Arteriosclerosis, Thrombosis, and Vascular Biology 35(2): 280-287.
- Wezel A., Lagraauw H.M., Velden D. van der, Jager S.C. de, Quax P.H.A., Kuiper J. & Bot I. (2015), Mast cells mediate neutrophil recruitment during atherosclerotic plaque progression, Atherosclerosis 241(2): 289-296.
- Wezel A., Welten S.M., Razawy W., Lagraauw H.M., Vries M.R. de, Goossens E.A., Boonstra M.C., Hamming J.F., Kandimalla E.R, Kuiper J., Quax P.H.A, Nossent A.Y. & Bot I. (2015), Inhibition of MicroRNA-494 Reduces Carotid Artery Atherosclerotic Lesion Development and Increases Plaque Stability, Annals of Surgery 262(5): 841-848.
- Frodermann V., Puijvelde G.H. van, Wierts L., Lagraauw H.M., Foks A.C., Santbrink P.J. van, Bot I., Kuiper J. & Jager S.C. de (2015), Oxidized low-density lipoprotein-induced apoptotic dendritic cells as a novel therapy for atherosclerosis, Journal of Immunology 194(5): 2208-2218.
- Lagraauw H.M., Kuiper J. & Bot I. (2015), Acute and chronic psychological stress as risk factors for cardiovascular disease: Insights gained from epidemiological, clinical and experimental studies, Brain, Behavior, and Immunity 50: 18-30.
- Wezel A., Quax P.H., Kuiper J. & Bot I. (2015), The role of mast cells in atherosclerosis, Hämostaseologie 35(2): 113-120.
- Wezel A., Vries M.R. de, Lagraauw H.M., Foks A.C., Kuiper J., Quax P.H.A. & Bot I. (2014), Complement factor C5a induces atherosclerotic plaque disruptions, Journal of Cellular and Molecular Medicine 18(10): 2020-2030.
- Rensing K.L., De Jager S.C., Stroes E.S., Vos M., Twickler M.T., Dallinga-Thie G.M., Vries C.J. de, Kuiper J., Bot I. & Thüsen J.H. von der (2014), Akt2/LDLr double knockout mice display impaired glucose tolerance and develop more complex atherosclerotic plaques than LDLr knockout mice, Cardiovascular Research 101(2): 277-287.
- Hoogendoorn S., Puijvelde G.H.M. van, Kuiper J., Marel G.A. van der & Overkleeft H.S. (2014), A Multivalent Ligand for the Mannose-6-Phosphate Receptor for Endolysosomal Targeting of an Activity-Based Probe, Angewandte Chemie (International Edition) 53(41): 10975-10978.
- Bot I., Daissormont I.T., Zernecke A., Puijvelde G.H.M. van, Kramp B., Jager S.C. de, Sluimer J.C., Manca M., Hérias V., Westra M.M., Bot M., Santbrink P.J. van, Berkel T.J.C. van, Su L., Skjelland M., Gullestad L., Kuiper J., Halvorsen B., Aukrust P., Koenen R.R., Weber C. & Biessen E.A. (2014), CXCR4 blockade induces atherosclerosis by affecting neutrophil function, Journal of Molecular and Cellular Cardiology 74: 44-52.
- Willems S., Velden D. van der, Quax P.H., Borst G.J. de, Vries J.P. de, Moll F.L, Kuiper J., Toes R.E, Jager S.C. de, Kleijn D.P. de, Hoefer I.E., Pasterkamp G. & Bot I. (2014), Circulating immunoglobulins are not associated with intraplaque mast cell number and other vulnerable plaque characteristics in patients with carotid artery stenosis, PLoS ONE 9(2): e88984.
- Maiwald S., Sivapalaratnam S., Motazacker M.M., Capelleveen J.C. van, Bot I., Jager S.C. de, Eck M. van, Jolley J., Kuiper J., Stephens J., Albers C.A., Vosmeer C.R., Kruize H., Geerke D.P., Wal A.C. van der, Loos C.M. van der, Kastelein J.J., Trip M.D., Ouwehand W.H., Dallinga-Thie G.M. & Hovingh G.K. (2014), Mutation in KERA identified by linkage analysis and targeted resequencing in a pedigree with premature atherosclerosis, PLoS ONE 9(5): e98289.
- Lagraauw H.M., Westra M.M., Bot M., Wezel A., Santbrink P.J. van, Pasterkamp G., Biessen E.A.L., Kuiper J. & Bot I. (2014), Vascular neuropeptide Y contributes to atherosclerotic plaque progression and perivascular mast cell activation, Atherosclerosis 235(1): 196-203.
- Foks A.C., Ran I.A., Wasserman L., Frodermann V., Borg M.N. ter, Jager S.C. de, Santbrink P.J. van, Yagita H., Akiba H., Bot I., Kuiper J. & Puijvelde G.H.M. van (2013), T-cell immunoglobulin and mucin domain 3 acts as a negative regulator of atherosclerosis, Arteriosclerosis, Thrombosis, and Vascular Biology 33(11): 2558-2565.
- Eisenberg E.H., Hillaert M.A., Ruijter H.M. den, Sels J.W., Scholtes V.P., Nathoe H.M., Kuiper J., Jukema J.W., Doevendans P.A., Pasterkamp G. & Hoefer I.E. (2013), Toll-Like Receptor induced CD11b and L-selectin response in patients with coronary artery disease, PLoS ONE 8(4): e60467.
- Karper J.C., Ewing M.M., Vries M.R. de, Jager S.C. de, Peters E.A., Boer H.C. de, Zonneveld A.J. van, Kuiper J., Huizinga E.G., Brondijk T.H., Jukema J.W. & Quax P.H. (2013), TLR Accessory Molecule RP105 (CD180) Is Involved in Post-Interventional Vascular Remodeling and Soluble RP105 Modulates Neointima Formation, PLoS ONE 8(7): e67923.
- Foks A.C., Puijvelde G.H.M. van, Bot I., Borg M.N. ter, Habets K.L., Johnson J.L., Yagita H., Berkel T.J. van & Kuiper J. (2013), Interruption of the OX40-OX40 ligand pathway in LDL receptor-deficient mice causes regression of atherosclerosis, Journal of Immunology 191(9): 4573-4580.
- Rensing K.L., De Jager S.C., Stroes E.S., Vos M., Twickler M.T., Dallinga-Thie G.M., De Vries C.J., Kuiper J., Bot I. & Von der Thusen J.H. (2013), Akt2/LDLr double knockout mice display impaired glucose tolerance and develop more complex atherosclerotic plaques than LDLr knockout mice, Cardiovascular Research 101(2): .
- Willems S., Vink A., Bot I., Quax P.H., De Borst G.J., De Vries J.P., Van de Weg S.M., Moll F.L., Kuiper J., Kovanen P.T., De Kleijn D.P., Hoefer I.E. & Pasterkamp G. (2013), Leukocyte-specific CCL3 deficiency inhibits atherosclerotic lesion development by affecting neutrophil accumulation, Arteriosclerosis and thrombosis: a journal of vascular biology/American Heart Associati 33(3): pp. e75-83.
- Karper J.C., De Jager S.C.A., Ewing M.M., De Vries M.R., Bot I., Van Santbrink P.J., Redeker A., Mallat Z., Binder C.J., Arens R., Jukema J.W., Kuiper J. & Quax P.H.A. (2013), An Unexpected Intriguing Effect of Toll-Like Receptor Regulator RP105 (CD180) on Atherosclerosis Formation With Alterations on B-Cell Activation, Arteriosclerosis, Thrombosis, and Vascular Biology 33(12): 2810-2817.
- De Vries Margreet R., Wezel Anouk, Schepers Abbey, Van Santbrink Peter J., Woodruff Trent M., Niessen Hans W.M., Hamming Jaap F., Kuiper Johan, Bot Ilze & Quax Paul H.A. (2013), Complement factor C5a as mast cell activator mediates vascular remodelling in vein graft disease, Cardiovascular Research 97(2): 311-320.
- Willems Sanne, Vink Aryan, Bot Ilze, Quax Paul H.A., De Borst Gert Jan, De Vries Jean-Paul P.M., Van de Weg Sander M., Moll Frans L., Kuiper Johan, Kovanen Petri T., De Kleijn Dominique P.V., Hoefer Imo E. & Pasterkamp Gerard (2013), Mast cells in human carotid atherosclerotic plaques are associated with intraplaque microvessel density and the occurrence of future cardiovascular events, European Heart Journal 34(48): 3699-3706.
- Ewing M.M., Karper J.C., Abdul S., De Jong R.C.M., Peters H.A.B., De Vries M.R., Redeker A., Kuiper J., Toes R.E.M., Arens R., Jukema J.W. & Quax P.H.A. (2013), T-cell co-stimulation by CD28-CD80/86 and its negative regulator CTLA-4 strongly influence accelerated atherosclerosis development, International Journal of Cardiology 168(3): 1965-1974.
- Van der Veer Eric P., De Bruin Ruben G., Kraaijeveld Adriaan O., De Vries Margreet R., Bot Ilze, Pera Tonio, Segers Filip M., Trompet Stella, Van Gils Janine M., Roeten Marko K., Beckers Cora M., Van Santbrink Peter J., Janssen Anique, Van Solingen Coen, Swildens Jim, De Boer Hetty C., Peters Erna A., Bijkerk Roel, Rousch Mat, Doop Merijn, Kuiper Johan, Schalij Martin Jan, Van der Wal Allard C., Richard Stephane, Van Berkel Theo J.C., Pickering J. Geoffrey, Hiemstra Pieter S., Goumans Marie Jose, Rabelink Ton J., De Vries Antoine A.F., Quax Paul H.A., Jukema J. Wouter, Biessen Erik A.L. & Van Zonneveld Anton Jan (2013), Quaking, an RNA-Binding Protein, Is a Critical Regulator of Vascular Smooth Muscle Cell Phenotype, Circulation Research 113(9): 1065-1075.
- Hoefer Imo E., Sels Jan-Willem, Jukema J. Wouter, Bergheanu Sandrin, Biessen Erik, McClellan Elizabeth, Daemen Mat, Doevendans Pieter, De Groot Philip, Hillaert Marieke, Horsman Sebastiaan, Ilhan Mustafa, Kuiper Johan, Pijls Nico, Redekop Ken, Van der Spek Peter, Stubbs Andrew, Van de Veer Eric, Waltenberger Johannes, Van Zonneveld Anton-Jan & Pasterkamp Gerard (2013), Circulating cells as predictors of secondary manifestations of cardiovascular disease: design of the CIRCULATING CELLS study, Clinical Research in Cardiology 102(11): 847-856.
- Karper J., De Jager S.C.A., Ewing M.M., De Vries M.R., Arens R., Bot I., Jukema J.W., Kuiper J. & Quax P. (2013), RP105 (cd180) as a TLR-4 regulator ameliorates atherosclerosis via its role on B-cells, European Heart Journal 34: 441-441.
- De Jager S.C.A., Van Puijvelde G.H., Anas A.A., Bot M., Asbach M., Schoneveld A., Habets K.L.L., Foks A.C., Pasterkamp G., Van der Poll T. & Kuiper J. (2013), Leukocyte TLR5 deficiency inhibits atherosclerosis by reduced macrophage recruitment and defective t cell responsiveness, Cardiology 126: 281-281.
- Van Berkel T., Kuiper J. & Van Eck M. (2013), Macrophage cholesterol homeostasis and atherosclerosis, Cardiology 126: 199-199.
- Hoekstra M., Frodermann V., Aardweg T. van den, Sluis R.J. van der & Kuiper J. (2013), Leukocytosis and Enhanced Susceptibility to Endotoxemia but Not Atherosclerotic in Adrenalectomized APOE Knockout Mice, PLoS ONE 8(11): e80441.
- Bot M., Jager S.C., MacAleese L., Lagraauw H.M., Berkel T.J.C. van, Quax P.H.A., Kuiper J., Heeren R.M., Biessen E.A. & Bot I. (2013), Lysophosphatidic acid triggers mast cell-driven atherosclerotic plaque destabilization by increasing vascular inflammation, Journal of Lipid Research 54(5): 1265-1274.
- Kuiper J., Quax P.H. & Bot I. (2013), Anti-apoptotic serpins as therapeutics in cardiovascular diseases, Cardiovascular & hematological disorders drug targets 13(2): 111-22.
- Foks A.C., Ran I.A., Frodermann V., Bot I., Santbrink P.J. van, Kuiper J. & Puijvelde G.H.M. van (2013), Agonistic anti-TIGIT treatment inhibits T cell responses in LDLr deficient mice without affecting atherosclerotic lesion development, PLoS ONE 8(12): e83134.
- Bot M., Veldhoven P.P. van, Jager S.C.A. de., Johnson J., Nijstad N., Santbrink P.J. van, Westra M.M., Hoeven G. van der, Gijbels M.J., Mueller-Tidow C., Varge G., Tietge U.J.F., Kuiper J., Berkel T.J.C. van, Nofer J.R., Bot I. & Biessen E.A.L. (2013), Hematopoietic Sphingosine 1-Phosphate Lyase Deficiency Decreases Atherosclerotic Lesion Development in LDL-Receptor Deficient Mice, PLoS ONE 8(5): e63360.
- Calpe-Berdiel L., Zhao Y., Graauw M. de, Ye D., Santbrink P.J. van, Mommaas A.M., Foks A., Bot M., Meurs I., Kuiper J., Mack J.T., Eck M. van, Tew K.D. & Berkel T.J.C. van (2012), Macrophage ABCA2 deletion modulates intracellular cholesterol deposition, affects macrophage apoptosis, and decreases early atherosclerosis in LDL receptor knockout mice, Atherosclerosis 223(2): 332-341.
- Sels J.W.E.M., Eisenberg E.H.A.M., Hoefer I.E., Zonneveld A.J. van, Kuiper J., Jukema J.W., Pijls N.H.J. & Pasterkamp G. (2012), Fractional Flow Reserve Is Not Associated with Inflammatory Markers in Patients with Stable Coronary Artery Disease, PLoS ONE 7(10): e46356.
- Meurs I., Calpe-Berdiel L., Habets K.L.L., Zhao Y., Korporaal S.J.A., Mommaas A.M., Josselin E., Hildebrand R.B., Ye D., Out R., Kuiper J., Berkel T.J.C. van, Chimini G. & Eck M. van (2012), Effects of Deletion of Macrophage ABCA7 on Lipid Metabolism and the Development of Atherosclerosis in the Presence and Absence of ABCA1, PLoS ONE 7(3): e30984.
- Wong M.C., Diepen J.A. van, Hu L., Guigas B., Boer H.C. de, Puijvelde G.H.M. van, Kuiper J., Zonneveld A.J. van, Shoelson S.E., Voshol P.J., Romijn J.A., Havekes L.M., Tamsma J.T., Rensen P.C., Hiemstra P.S. & Berbée J.F. (2012), Hepatocyte-specific IKKβ expression aggravates atherosclerosis development in APOE*3-Leiden mice, Atherosclerosis 220(2): 362-368.
- Calpe-Berdiel L., Zhao Y., Graauw M. de, Ye D., Santbrink P.J. van, Mommaas A.M., Foks A.C., Bot M., Meurs I., Kuiper J., Mack J.T., Eck M. van, Tew K.D. & Berkel T.J.C. van (2012), Macrophage ABCA2 deletion modulates intracellular cholesterol deposition, affects macrophage apoptosis, and decreases early atherosclerosis in LDL receptor knockout mice, Atherosclerosis 223(2): 332-341.
- Jager S.C. de, Karper J.C., Bot I., Vries M.R. de, Binder C.J., Kuiper J. & Quax P.H. (2012), Extracellular toll like receptor regulator RP105/CD180 ameliorates atherosclerosis via its role on B cells, Immunology 137: 296-296.
- Foks A.C., Bot I., Frodermann V., Jager S.C.A. de, Borg M. ter, Santbrink P.J. van, Yagita H., Kuiper J. & Puijvelde G.H.M. van (2012), Interference of the CD30-CD30L pathway reduces atherosclerosis development, Immunology 137: 478-478.
- Kuiper J. (2012), Immunomodulation of atherosclerosis, Vascular Pharmacology 56(5-6): 337-337.
- Bot I., Vries H. de, Bot M., Berkel T.J.C. van, IJzerman A.P. & Kuiper J. (2012), Adenosine A(2B) receptor agonism inhibits vascular smooth muscle cell proliferation and intimal hyperplasia in ApoE deficient mice, Vascular Pharmacology 56(5-6): 349-350.
- Vries M.R. de, Wezel A., Schepers A., Kuiper J., Bot I. & Quax P.H.A. (2012), Mast cell activation via complement factor C5a modulates vein graft remodeling and accelerated atherosclerosis, Vascular Pharmacology 56(5-6): 372-372.
- Ramos O., Jager S.C. de, Santbrink P.J. van, Borg M. ter, Sluis R. van der & Kuiper J. (2012), Inhibition of IL-27 attenuates atherosclerosis, Immunology 137: 255-255.
- Hoekstra M., Sluis R.J. van der, Kuiper J. & Berkel T.J.C. van (2012), Nonalcoholic fatty liver disease is associated with an altered hepatocyte microRNA profile in LDL receptor knockout mice, Journal of Nutritional Biochemistry 23(6): 622-628.
- Lammers B., Zhao Y., Foks A.C., Hildebrand R.B., Kuiper J., Berkel T.J. van & Eck M. van (2012), Leukocyte ABCA1 remains atheroprotective in splenectomized LDL receptor knockout mice, PLoS ONE 7(10): e48080.
- Karper J.C., Ewing M.M., Habets K.L., Vries M.R. de, Peters E.A., Oeveren-Rietdijk A.M. van, Boer H.C. de, Hamming J.F., Kuiper J., Kandimalla E.R., La Monica N., Jukema J.W. & Quax P.H. (2012), Blocking Toll-Like Receptors 7 and 9 Reduces Postinterventional Remodeling via reduced Macrophage Activation, Foam Cell Formation, and Migration, Arteriosclerosis and thrombosis: a journal of vascular biology/American Heart Associati 32(8): 72-80.
- Bot I., Vries H. de, Korporaal S.J.A., Foks A.C., Bot M., Veldhoven J.P.D., Borg M.N.D. ter, Santbrink P.J. van, Berkel T.J. van.C., Kuiper J. & Ijzerman A.P. (2012), Adenosine A(2B) Receptor Agonism Inhibits Neointimal Lesion Development After Arterial Injury in Apolipoprotein E-Deficient Mice, Arteriosclerosis, Thrombosis, and Vascular Biology 32(9): 2197-2205.
- Foks A.C., Bot I., Frodermann V., Jager S.C. de, Borg M. ter, Santbrink P.J. van, Yagita H., Kuiper J. & Puijvelde G.H.M. van (2012), Interference of the CD30-CD30L pathway reduces atherosclerosis development, Arteriosclerosis, Thrombosis, and Vascular Biology 32(12): 2862-2868.
- Lombardo E., Roomen C.P.A.A. van, Van Puijvelde G.H., Ottenhoff R., Eijk M. van, Aten J., Kuiper J., Overkleeft H.S., Groen A.K., Verhoeven A.J., Aerts J.M.F.G. & Bietrix F. (2012), Correction of Liver Steatosis by a Hydrophobic Iminosugar Modulating Glycosphingolipids Metabolism, PLoS ONE 7(10): 38520.
- Wong M.C., Diepen J.A. van, Hu L., Guigas B., Boer H.C., Puijvelde G.H. van, Kuiper J., Zonneveld A.J. van, Shoelson S.E., Voshol P.J., Romijn J.A., Havekes L.M., Tamsma J.T., Rensen P.C.N., Hiemstra P.S. & Berbee J.F.P. (2012), Hepatocyte-specific IKK beta expression aggravates atherosclerosis development in APOE*3-Leiden mice, Atherosclerosis 220(2): 362-368.
- Korporaal S.J.A., Meurs I., Hauer A.D., Hildebrand R.B., Hoekstra M., Ten Cate H., Pratico D., Akkerman J.W.N., Berkel T.J.C. van, Kuiper J. & Eck M. van (2011), Deletion of the HDL receptor SR-BI in mice modulates thrombosis susceptibility and indirectly affects platelet function by elevation of plasma free cholesterol, Arteriosclerosis and thrombosis: a journal of vascular biology/American Heart Associati 31(1): 34-42.
- Hoogendoorn S., Habets K.L., Passemard S., Kuiper J., Marel G.A. van der, Florea B.I. & Overkleeft H.S. (2011), Targeted pH-dependent fluorescent activity-based cathepsin probes, Chemical Communications 47(33): .
- Wong M.C., Van Diepen J.A., Hu L., Guigas B., De Boer H.C., Van Puijvelde G.H., Kuiper J., Van Zonneveld A.J., Shoelson S.E., Voshol P.J., Romijn J.A., Havekes L.M., Tamsma J.T., Rensen P.C., Hiemstra P.S. & Berbee J.F. (2011), Hepatocyte-specific IKKbeta expression aggravates atherosclerosis development in APOE*3-Leiden mice, Atherosclerosis : .
- Vries M.R. de, Wezel A., Schepers A., Kuiper J., Bot I. & Quax P.H.A. (2011), Complement factor C5A modulates vein graft remodeling and accelerated atherosclerosis via interference in mast cell activation, Atherosclerosis Supplements 12(1): 79-79.
- Wezel A., De Vries M.R., Schepers A., Kuiper J., Bot I. & Quax P. (2011), Complement-factor C5a modulates vein graft remodeling and accelerated atherosclerosis via interference in Mast cell activation, Molecular Immunology 48(14): 1693-1693.
- Van Puijvelde G., Van Osch P., Bot I., Foks A., Ter Borg M., Habets K., Van Berkel T. & Kuiper J. (2011), NKT cells aggravate the development of abdominal aortic aneurysms, Immunology 135: 173-173.
- De Jager S.C. & Kuiper J. (2011), Vaccination strategies in atherosclerosis, Thrombosis and Haemostasis 106(5): .
- Es T. van, Puijvelde G.H.M. van, Michon I.N., Wanrooij E.J. van, Vos P. de, Peterse N., Berkel T.J. van & Kuiper J. (2011), IL-15 aggravates atherosclerotic lesion development in LDL receptor deficient mice, Vaccine 29(5): 976-983.
- Jager S.C. de, Bermudez B., Bot I., Koenen R.R., Bot M., Kavelaars A., Waard V. de, Heijnen C.J., Muriana F.J., Weber C., Berkel T.J.C. van, Kuiper J., Lee S.J., Abia R. & Biessen E.A. (2011), Growth differentiation factor 15 deficiency protects against atherosclerosis by attenuating CCR2-mediated macrophage chemotaxis, The Journal of Experimental Medicine 208(2): 217-225.
- Lammers B., Chandak P.G., Aflaki E., Puijvelde G.H.M. van, Radovic B., Hildebrand R.B., Meurs I., Out R., Kuiper J., Berkel T.J.C. van, Kolb D., Haemmerle G., Zechner R., Levak-Frank S., Eck M. van & Kratky D. (2011), Macrophage adipose triglyceride lipase deficiency attenuates atherosclerotic lesion development in low-density lipoprotein receptor knockout mice, Arteriosclerosis, Thrombosis, and Vascular Biology 31(1): 67-73.
- Lammers B., Chandak P.G., Aflaki E., Puijvelde G.H.M. van, Radovic B., Hildebrand R.B., Meurs I., Out R., Kuiper J., Berkel T.J.C. van, Kolb D., Haemmerle G., Zechner R., Levak-Frank S., Eck M. van & Kratky D. (2011), Macrophage adipose triglyceride lipase deficiency attenuates atherosclerotic lesion development in LDL receptor knockout mice, Arteriosclerosis, Thrombosis, and Vascular Biology 31(1): 67-73.
- Foks A.C., Frodermann V., Ter Borg M., Habets K.L., Bot I., Zhao Y., Van Eck M., Van Berkel T.J., Kuiper J. & Van Puijvelde G.H. (2011), Differential effects of regulatory T cells on the initiation and regression of atherosclerosis, Atherosclerosis 218(1): 53-60.
- Habets K.L., Puijvelde G.H.M. van, Duivenvoorde L.M. van, Wanrooij E.J. van, Vos P. de, Tervaert J.W., Berkel T.J.C. van, Toes R.E. & Kuiper J. (2010), Vaccination using oxidized low-density lipoprotein-pulsed dendritic cells reduces atherosclerosis in LDL receptor-deficient mice, Cardiovascular Research 85(3): 622-630.
- Korporaal S.J., Meurs I. van, Hauer A.D., Hildebrand R.B., Hoekstra M., Cate H.T., Pratico D., Akkerman J.W., Van Berkel T.J., Kuiper J. & Van Eck M. (2010), Deletion of the high-density lipoprotein receptor scavenger receptor BI in mice modulates thrombosis susceptibility and indirectly affects platelet function by elevation of plasma free cholesterol, Arteriosclerosis, Thrombosis, and Vascular Biology 31(1): .
- Hoekstra M., Van der Lans C.A., Halvorsen B., Gullestad L., Kuiper J., Aukrust P., Van Berkel T.J. & Biessen E.A. (2010), The peripheral blood mononuclear cell microRNA signature of coronary artery disease, Biochemical and Biophysical Research Communications 394(3): .
- Hoekstra M., Li Z., Kruijt J.K., Van Eck M., Van Berkel T.J. & Kuiper J. (2010), The expression level of non-alcoholic fatty liver disease-related gene PNPLA3 in hepatocytes is highly influenced by hepatic lipid status, Journal of Hepatology 52(2): .
- Lammers B., Chandak P.G., Aflaki E., Van Puijvelde G.H., Radovic B., Hildebrand R.B., Meurs I. van, Out R., Kuiper J., Van Berkel T.J., Kolb D., Haemmerle G., Zechner R., Levak-Frank S., Van Eck M. & Kratky D. (2010), Macrophage adipose triglyceride lipase deficiency attenuates atherosclerotic lesion development in low-density lipoprotein receptor knockout mice, Arteriosclerosis, Thrombosis, and Vascular Biology 31(1): .
- Van Es T., Van Puijvelde G.H., Michon I.N., Van Wanrooij E.J., De Vos P., Peterse N., Van Berkel T.J. & Kuiper J. (2010), IL-15 aggravates atherosclerotic lesion development in LDL receptor deficient mice, Vaccine 29(5): .
- Habets K.L., Van Puijvelde G.H., Van Duivenvoorde L.M., Van Wanrooij E.J., De Vos P., Tervaert J.W., Van Berkel T.J., Toes R.E. & Kuiper J. (2010), Vaccination using oxidized low-density lipoprotein-pulsed dendritic cells reduces atherosclerosis in LDL receptor-deficient mice, Cardiovascular Research 85(3): .
- Es T. van, Puijvelde G.H.M. van, Foks A.C., Habets K.L., Bot I., Gilboa E., Berkel T.J. van & Kuiper J. (2010), Vaccination against Foxp3(+) regulatory T cells aggravates atherosclerosis, Atherosclerosis 209(1): 74-80.
- Van Es T., Van Puijvelde G.H., Foks A.C., Habets K.L., Bot I., Gilboa E., Van Berkel T.J. & Kuiper J. (2010), Vaccination against Foxp3(+) regulatory T cells aggravates atherosclerosis, Atherosclerosis 209(1): .
- Es T. van, Puijvelde G.H.M. van, Ramos O.H., Segers F.M., Joosten L.A., Berg W.B. van den, Michon I.M., Vos P. de, Berkel T.J.C. van & Kuiper J. (2009), Attenuated atherosclerosis upon IL-17R signaling disruption in LDLr deficient mice, Biochemical and Biophysical Research Communications 388(2): 261-265.
- Hoekstra M., Ye D., Hildebrand R.B., Zhao Y., Lammers B., Stitzinger M., Kuiper J., Berkel T.J.C. van & Eck M. van (2009), Scavenger receptor class B type I-mediated uptake of serum cholesterol is essential for optimal adrenal glucocorticoid production, Journal of Lipid Research 50(6): 1039-1046.
- Van Es T., Van Puijvelde G.H., Ramos O.H., Segers F.M., Joosten L.A., Van den Berg W.B., Michon I.M., De Vos P., Van Berkel T.J.C. & Kuiper J. (2009), Attenuated atherosclerosis upon IL-17R signaling disruption in LDLr deficient mice, Biochemical and Biophysical Research Communications 388(2): 261-5.
- Hillaert W., Verdoes M., Florea B.I., Saragliadis N., Habets K., Kuiper J., Van Calenbergh S., Ossendorp F., Van der Marel G.A., Driessen C. & Overkleeft H.S. (2009), Receptor-Mediated Targeting of Cathepsins in Professional Antigen Presenting Cells, Angewandte Chemie - International Edition in English 48(9): 1629-1632.
- Puijvelde G.H.M. van, Wanrooij E.J. van, Hauer A.D., Vos P. de, Berkel T.J.C. van & Kuiper J. (2009), Effect of natural killer T cell activation on the initiation of atherosclerosis, Thrombosis and Haemostasis 102(2): 223-230.
- Jager S.C. de, Canté-Barrett K., Bot I., Husberg C., Puijvelde G.H.M. van, Santbrink P.J. van, Yndestad A., Oever J.M. van den, Kuiper J., Berkel T.J.C. van, Lipp M., Zwaginga J.J., Fibbe W.E., Aukrust P. & Biessen E.A. (2009), Impaired effector memory T-cell regulation facilitates graft versus host disease in CCR7-deficient bone marrow transplant chimeras, Transplantation 88(5): 631-639.
- Out R., Hoekstra M., Habets K.L., Meurs I., Waard V. de, Hildebrand R.B., Wang Y., Chimini G., Kuiper J., Berkel T.J.C. van & Eck M. van (2008), Combined deletion of macrophage ABCA1 and ABCG1 leads to massive lipid accumulation in tissue macrophagesand distinct atherosclerosis at relatively low plasma cholesterol levels, Arteriosclerosis, Thrombosis, and Vascular Biology 28(2): 258-264.
- Hauer A.D., Habets K.L., Wanrooij E.J.A. van, Vos P. de, Krueger J., Reisfeld R.A., Berkel T.J.C. van & Kuiper J. (2008), Vaccination against TIE2 reduces atherosclerosis, Atherosclerosis : .
- Wanrooij E.J.A. van, Vos P. de, Bixel M.G., Vestweber D., Berkel T.J.C. van & Kuiper J. (2008), Vaccination against CD99 inhibits atherogenesis in low-density lipoprotein, Cardiovascular Research 78(3): 590-596.
- Out R., Jessup W., Goff L.J., Hoekstra M., Gelissen I.C., Zhao Y., Kritharides L., Chimini G., Kuiper J., Chapman M.J., Huby T., Berkel T.J.C. van & Eck M. van (2008), Coexistence of foam cells and hypocholesterolemia in mice lacking the ABC, Circulation Research 102(1): 113-120.
- Wanrooij E.J.A. van, Jager S.C.A. de, Es T. van, Vos P., Birch H.L., Owen D.A., Watson R.J., Biessen E.A.L., Chapman G.A. & Berkel T.J.C. van (2008), CXCR3 antagonist NBI-74330 attenuates atherosclerotic plaque formation in LDL receoptor-deficient mice, Arteriosclerosis, Thrombosis, and Vascular Biology 28(2): 251-257.
- Puijvelde G.H.M. van, Es T. van, Habets K.L., Hauer A.D., Berkel T.J.C. van & Kuiper J. (2008), A vaccine against atherosclerosis: myth or reality?, Future Cardiology 4(2): 125-33.
- Boon R.A., Fledderus J.O., Volger O.L., Wanrooij E.J.A. van, Pardali E., Weesie F., Kuiper J., Pannekoek H., Dijke P. ten & Horrevoets A.J.G. (2007), KLF2 suppresses TGF-β signaling in endothelium through induction of Smad7 and inhibition of AP-1, Arteriosclerosis, Thrombosis, and Vascular Biology 27: 532-539.
- Wanrooij E.J. van, Puijvelde G.H.M. van, Vos P. de, Yagita H., Berkel T.J.C. van & Kuiper J. (2007), Interruption of the Tnfrsf4/Tnfsf4 (OX40/OX40L) pathway attenuates atherogenesis in low-density lipoprotein receptor-deficient mice, Arteriosclerosis, Thrombosis, and Vascular Biology 27(1): 204-210.
- Puijvelde G.H.M. van, Es T. van, Wanrooij E.J. van, Habets K.L., Vos P. de, Zee R. van der, Eden W. van, Berkel T.J.C. van & Kuiper J. (2007), Induction of oral tolerance to HSP60 or an HSP60-peptide activates T cell regulation and reduces atherosclerosis, Arteriosclerosis, Thrombosis, and Vascular Biology 27(12): 2677-83.
- Volger O.L., Fledderus J.O., Kisters N., Fontijn R.D., Moerland P.D., Kuiper J., Berkel T.J.C. van, Bijnens A.P., Daemen M.J., Pannekoek H. & Horrevoets A.J.G. (2007), Distinctive expression of chemokines and transforming growth factor-β signaling in human arterial endothelium during atherosclerosis, The American Journal of Pathology 171: 326-337.
- Kuiper J., Puijvelde G.H.M. van, Wanrooij E.J.A. van, Es T. van, Habets K.L., Hauer A.D. & Berkel T.J.C. van (2007), Immunomodulation of the inflammatory response in atherosclerosis, Current Opinion in Lipidology 18: 521-526.
- Hauer A.D., Puijvelde G.H.M. van, Peterse N., Vos P. de, Weel V. van, Wanrooij E.J.A. van, Biessen E.A.L., Quax P.H., Niethammer A.G., Reisfeld R.A., Berkel T.J.C. van & Kuiper J. (2007), Vaccination against VEGFR2 attenuates initiation and progression of atherosclerosis, Arteriosclerosis, Thrombosis, and Vascular Biology 27: 2050-2057.
- Fledderus J.O., Thienen J.V. van, Boon R.A., Dekker R.J., Rohlena J., Volger O.L., Bijnen A.B., Daemen M.J., Kuiper J., Berkel T.J.C. van, Pannekoek H. & Horrevoets A.J.G. (2007), Prolonged shear stress and KLF2 suppress constitutive proinflammatory transcription through inhibition of ATF2, Blood 109: 4249-4257.
- Out R., Hoekstra M., Meurs I., Vos P. de, Kuiper J., Eck M. van & Berkel T.J.C. van (2007), Total body ABCG1 expression protects against early atherosclerotic lesion development in mice, Arteriosclerosis, Thrombosis, and Vascular Biology 27: 594-599.
- Wanrooij E.J. van, Puijvelde G.H. van, Vos P. de, Yagita H., Berkel T.J.C. van & Kuiper J. (2007), Interruption of the Tnfrsf4/Tnfsf4 (OX40/)X40L) pathway attenuates atherogenesis in low-density lipoprotein receptor-deficient mice, Arteriosclerosis, Thrombosis, and Vascular Biology 27(1): 204-210.
- Puijvelde G.H.M. van, Es T. van, Wanrooij E.J.A. van, Habets K.L., Vos P. de, Zee R. van der, Eden W. van, Berkel T.J.C. van & Kuiper J. (2007), Induction of oral tolerance to HSP60 or an HSP60-peptide activates T cell regulation and reduces atherosclerosis, Arteriosclerosis, Thrombosis, and Vascular Biology 27: 2677-2683.
- Kuiper J., Puijvelde G.H.M. van, Wanrooij E.J. van, Es T. van, Habets K., Hauer A.D. & Berkel T.J.C. van (2007), Immunomodulation of the inflammatory response in atherosclerosis, Current Opinion in Lipidology 18(5): 521-526.
- Hauer A.D., Puijvelde G.H.M. van, Peterse N., Vos P. de, Weel V. van, Wanrooij E.J. van, Biessen E.A., Quax P.H., Niethammer A.G., Reisfeld R.A., Berkel T.J.C. van & Kuiper J. (2007), Vaccination against VEGFR2 attenuates initiation and progression of atherosclerosis, Arteriosclerosis, Thrombosis, and Vascular Biology 27(9): 2050-2057.
- Hoekstra M., Stitzinger M., Out R., Van Eck M., Van Berkel T.J. & Kuiper J. (2007), Nutrition-induced changes in adiponutrin gene expression implicate a role for adiponutrin in hepatic lipogenesis, Atherosclerosis Supplements 8(1): 211-211.
- Hoekstra M., Stitzinger M., Wanrooij E.J.A. van, Michon I.N., Kruijt J.K., Kamphorst J.T., Eck M. van, Vreugdenhil E., Berkel T.J.C. van & Kuiper J. (2006), Microarray analysis indicates an important role for FABP5 and putative novel FABPs on a Western-type diet, Journal of Lipid Research 47: 2198-2207.
- Puijvelde G.H.M. van, Hauer A.D., Vos P. de, Heuvel R. van den, Herwijnen M.J., Zee R. van der, Eden W. van, Berkel T.J.C. van & Kuiper J. (2006), Induction of oral tolerance to oxidized low-density lipoprotein ameliorates atherosclerosis, Circulation 31: 1968-1976.
- Wanrooij E.J.A. van, Puijvelde G.H.M. van, Vos P. de, Yagita H., Berkel T.J.C. van & Kuiper J. (2006), Interruption of the Tnfrsf4/Tnfsf4 (OX40/OX40L) pathway attenuates atherogenesis in low-density lipoprotein receptor-deficient mice, Arteriosclerosis, Thrombosis, and Vascular Biology : .
- Boon R.A., Fledderus J.O., Volger O.L., Wanrooij E.J.A. van, Pardali E., Weesie F., Kuiper J., Pannekoek H., Dijke P. ten & Horrevoets A.J.G. (2006), KLF2 suppresses TGF- signaling in endothelium through induction of Smad7 and inhibition of AP-1, Arteriosclerosis, Thrombosis, and Vascular Biology : .
- Bijnens A.P., Lutgens E., Ayoubi T., Kuiper J., Horrevoets A.J.G. & Daemen M.J. (2006), Genome-wide expression studies of atherosclerosis: critical issues in methodology, analysis, interpretation of transcriptomics data, Arteriosclerosis, Thrombosis, and Vascular Biology 26: 1226-1235.
- Hauer A.D., Vos P. de, Peterse N., Cate H. ten, Berkel T.J.C. van, Stassen F.R. & Kuiper J. (2006), Delivery of Chlamydia pneumoniae to the vessel wall aggravates atherosclerosis in LDLr(-/-) mice, Cardiovascular Research 69: 280-288.
- Puijvelde G.H.M. van, Hauer A.D., Vos P. de, Heuvel R. van den, Herwijnen M.J. van, Zee R. van der, Eden W. van, Berkel T.J.C. van & Kuiper J. (2006), Induction of oral tolerance to oxidized low-density lipoprotein ameliorates atherosclerosis, Circulation 114(18): 1968-1976.
- Hauer A.D., Uyttenhove C., Vos P. de, Stroobant V., Renauld J.C., Berkel T.J.C. van, Snick J. van & Kuiper J. (2005), Blockade of interleukin-12 function by protein vaccination attenuates atherosclerosis, Circulation 112: 1054-1062.
- Berkel T.J.C. van, Out R., Hoekstra M., Kuiper J., Biessen E.A.L. & Eck M. van (2005), Scavenger receptors: friend or foe in atherosclerosis?, Current Opinion in Lipidology 16: 525-535.
- Wanrooij E.J.A. van, Happe H., Hauer A.D., Vos P., Imanishi T., Fujiwara H., Berkel T.J.C. van & Kuiper J. (2005), HIV Entry Inhibitor TAK-779 Attenuates Atherogenesis in Low-Density Lipoprotein Receptor-Deficient Mice, Arteriosclerosis, Thrombosis, and Vascular Biology 25: 2642-2647.
- Meurs I., Hoekstra M., Wanrooij E.J.A. van, Hildebrand RB, Kuiper J., Kuipers F., Hardeman M.R., Berkel T.J.C. van & Eck M. van (2005), HDL cholesterol levels are an important factor for determining the lifespan of erythrocytes, Experimental Hematology 33: 1309-1319.
- Guo J., Waard V. de, Eck M. van, Hildebrand RB, Wanrooij E.J.A. van, Kuiper J., Maeda N., Benson M.H., Groot P.H.E. & Berkel T.J.C. van (2005), Repopulation of apolipoprotein E knockout mice with CCR2-deficient progenitor cells does not inhibit ongoing atherosclerotic lesion development, Arteriosclerosis, Thrombosis, and Vascular Biology 25: 1014-1019.
- Hauer A.D., Vos P. de, Peterse N., Weel V., Quax P.H., Puijvelde G.H.M. van, Berkel T.H.J. van, Reisfeld R.A. & Kuiper J. (2005), Vaccination against VEGF receptor 2 blocks initiation and progression of atherosclerosis, Atherosclerosis Supplements 6(1): 68-68.
- Rensen P.C.N., Berbee J.F.P., Schippers E.F., Dissel J.T. van, Bakker-Woudenberg A.J.M., Leeuwen H.J. van, Haas C.J.C., Kessel K.P.M., Berkel T.J.C. van, Kuiper J., Kooistra T. & Havekes L.M. (2004), Apolipoproteins modulate inflammatory responses in rodents and humans: implications for sepsis, Shock 21: 153.
- Egmond M. van, Garderen E. van, Spriel A.B. van, Damen C.A., Amersfoort E.S. van, Zandbergen G. van, Hattum J. van, Kuiper J. & Winkel J.G. van de (2004), FcalphaRI-positive liver Kupffer cells: reappraisal of the fun of immunoglobulin A in immunity, Nature Medicine 6(6): 680-685.
- Nooijer R. de, Thüsen J.H. von der, Verkleij C.J.N., Kuiper J., Jukema J.W., Wall E.E. van der, Berkel T.J.C. van & Biessen E.A.L. (2004), Overexpression of IL-18 decreases intimal collagen content and promotes a vulnerable plaque phenotype in apolipoprotein-E-deficient mice, Arteriosclerosis, Thrombosis, and Vascular Biology 24: 2313-9.
- Berkel T.J.C. van, Thüsen J.H. von der, Kuiper J., Biessen E. & Eck M. van (2004), Genetic manipulation of macrophage and vascular genes in mouse models of atherosclerosis, International Congress Series 1262: 384-387.
- Lutters B., Molenaar T., Korporaal S., Akkerman J., Berkel T.J.C. van, Kuiper J. & Biessen E. (2004), Peptide antagonists specifically inhibit the interaction between P-selectin and platelet-exposed sulfatides and reduce platelet aggregation, Atherosclerosis Supplements 5(1): 12-12.
- Hauer A., Uyttenhove C., Vos P. de, Stroobant V., Renauld J., Berkel T.J.C. van, Snick J. van & Kuiper J. (2004), Vaccination against interleukin 12 attenuates atherosclerosis in LDL receptor deficient mice, Atherosclerosis Supplements 5(1): 41-42.
- Puijvelde G. van, Vos P. de, Zee R. van der, Eden W. van, Berkel T.J.C. van & Kuiper J. (2004), Oral tolerance with oxidized LDL reduces atherogenesis, Atherosclerosis Supplements 5(1): 43-43.
- Thüsen J.H. von der, Kuiper J., Berkel T.J.C. van & Biessen E.A.L. (2003), Interleukins in atherosclerosis: molecular pathways and therapeutic potential, Pharmacological Reviews 55: 133-166.
- Molenaar T.J.M., Twisk J., Haas S.A. de, Peterse N., Vogelaar B.J., Leeuwen S.H., Michon I.N., Berkel T.J.C. van, Kuiper J. & Biessen E.A.L. (2003), P-selectin as a candidate target in athero-sclerosis, Biochemical Pharmacology 66: 859-866.
- Amersfoort E.S. van, Berkel T.J.C. van & Kuiper J. (2003), Receptors, mediators, and mechanisms involved in bacterial sepsis and septic shock, Clinical Microbiology Reviews 16: 379-414.
- Nooijer R. de, Thusen J.H. von der, Kuiper J., Verkleij C.J., Berkel T.J.C. van, Levy S. & Biessen E.A. (2003), Overexpression of interleukin-18 decreases plaque stability apolipoprotein-E deficient mice, Arteriosclerosis, Thrombosis, and Vascular Biology 108(17): 224-224.
- Florea B.I., Molenaar T.J.M., Bot I., Michon I.N., Kuiper J., Berkel T.J.C. van, Junginger H.E., Biessen E.A.L. & Borchard G. (2003), Identification of an internalising peptide in differentiated Calu-3 cells by phage display technology; application to gene delivery to the airways, Journal of Drug Targeting 11(7): 383-390.
- Bot I., Thüsen J.H. von der, Donners M.M., Lucas A., Fekkes M.L., Jager S.C.A. de, Kuiper J., Daemen M.J., Berkel T.J.C. van, Heeneman S. & Biessen E.A.L. (2003), Serine protease inhibitor Serp-1 strongly impairs atherosclerotic lesion formation and induces a stable plaque phenotype in ApoE-/-mice, Circulation Research 93: 464-471.
- Velde E.T. van der, Vriend J.W.J., Theeuwes E., Murk Jansen H.D.M., Kuiper J., Hoekstra W.H.G.J. & Mulder B.J.M. (2003), Quality assurance measures in the CONCOR national registry and DNA-bank of patients with congenital heart disease in the Netherlands, IEEE, Computers in Cardiology 30: 395-398.
- Molenaar T.J.M., Michon I.N., Haas S.A. de, Berkel T.J.C. van & Biessen E.A.L. (2002), Uptake and processing of modified bacteriophage M13 in mice: implications for phage display, Virology 293: 182-191.
- Michon I.N., Penning L.C., Molenaar T.J.M., Berkel T.J.C. van & Kuiper J. (2002), The effect of TGF-beta receptor binding peptides on smooth muscle cells, Biochemical and Biophysical Research Communications 293: 1279-1286.
- Molenaar T.J.M., Appeldoorn C.C.M., Haas S.A. de, Michon I.N., Bonnefoy A., Hoylarts M.F., Pannekoek H., Berkel T.J.C. van, Kuiper J. & Biessen E.A.L. (2002), Specific inhibition of P-selectin-mediated cell adhesion by phage display-derived peptide antagonists, Blood 100: 3570-3577.
- Molenaar T.J.M., Korporaal S.J.A., Akkerman J.W., Berkel T.J.C. van, Kuiper J. & Biessen E.A.L. (2002), Peptide antagonists inhibit the interaction of P-selectin with sulfatide-containing liposomes and reduce platelet aggregation, Circulation 106: II-120.
- Rijken D.C., Kaaden M.E. van der, Groeneveld E., Barrett-Bergshoeff M.M., Berkel T.J.C. van & Kuiper J. (2002), Characterization of the binding of urokinase-type plasminogen activator to the asialoglycoprotein receptor, Thrombosis and Haemostasis 88: 83-88.
- Michon I.N., Hauer A.D., Thüsen J.H. von der, Molenaar T.J.M., Berkel T.J.C. van & Kuiper J. (2002), Targeting of peptides to restenotic vascular smooth muscle cells using phage display in vitro and in vivo, Biochimica et Biophysica Acta 1591: 87-97.
- Bot I., Thüsen J.H. von der, Donners M.M., Lucas A.R., Berkel T.J.C. van, Kuiper J., Heeneman S. & Biessen E.A.L. (2002), The serine protease inhibitor Serp-1 strongly impairs de novo atherosclerotic lesion formation in ApoE -/- mice, Circulation 106: II-300.
- Molenaar T.J.M., Berkel T.J.C. van, Kuiper J., Mayadas-Norton T. & Biessen E.A.L. (2002), Specific binding and cleavage of P-selectin by μ-calpain is mediated by a highly conserved pentapeptide motif, Circulation 106: II-150.
- Sliedregt L.A.J.M., Rossenberg S.M.W. van, Autar R., Valentijn A.R.P.M., Marel G.A. van der, Boom J.H. van, Piperi C., Merwe P.A. van der, Kuiper J., Berkel T.J.C. van & Biessen E.A. (2001), Design and synthesis of multivalent homing device for targeting to murine CD22, Bioorganic & Medicinal Chemistry 9(1): 85-97.
- Vries H.E., Buchner B., Berkel T.J.C. van & Kuiper J. (1999), Specific interaction of oxidized low density lipoprotein with macrophage-derived foam cells isolated from rabbit atherosclerotic lesions, Arteriosclerosis, Thrombosis, and Vascular Biology 19: 638-645.
- Vries H.E., Moor A.C.E., Dubbelman T.M.A.R., Berkel T.J.C. van & Kuiper J. (1999), Oxidized low-density lipoprotein as a delivery system for photosensitizers: implications for photodynamic therapy of atherosclerosis, Journal of Pharmacology and Experimental Therapeutics 289: 528-534.
- Kuiper J., Vries H.E., Moor A.C.E., Dubbelman T.M.A.R. & Berkel T.J.C. van (1998), Arteriosclerosis and photodynamic therapy: oxidatively modified LDL as a delivery system for photosensitizer, Circulation 98: I-635.
- Vries H.E., Ronke E., Reinders J.H., Berkel T.J.C. van & Kuiper J. (1998), Acute effects of oxidized low density lipoprotein on the metabolic responses of macrophages, The FASEB Journal 12: 111-118.
- Kaaden M.E. van der, Rijken D.C. & Kuiper J. (1998), Plasma clearance of urokinase-type plasminogen activator, Fibrinolysis and Proteolysis 12: 251-258.
- Oosten M. van, Bilt E. van de, Berkel T.J.C. van & Kuiper J. (1998), New scavenger receptor-like receptors for the binding of lipopolysaccharide to liver endothelial and Kupffer cells, Infection and Immunity 66: 5107-5112.
- Rensen P.C.N., Oosten M. van, Amersfoort E.S. van, Eck M. van, Kuiper J. & Berkel T.J.C. van (1998), Apolipoprotein E is increased by bacterial LPS in vivo and protects against LPS-induced lethality, Circulation 98: I-305.
- Biessen E.A.L., Vietsch H., Kuiper J. & Berkel T.J.C. van (1998), Liver uptake of phosphodiester oligodeoxynucleotides is mediated by scavenger receptor type binding sites, Molecular Pharmacology 53: 262-269.
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- lid Scientific Advisroy Board