Universiteit Leiden

nl en


Synthetic peptides, nucleic acids and molecular probes to study ADP-Ribosylation

This thesis presents the first synthetic peptides ADP-ribosylated on serine, threonine, tyrosine, arginine and cysteine.

Voorneveld, J.
08 september 2022
Thesis in Leiden Repository

Besides synthetic peptides, this thesis discusses the first synthetic route towards ADP-ribosylated nucleic acids. Furthermore, two photoaffinity probes for PARP1 have been developed and assessed in living cells and two activity based probes have been synthesized, designed for CD38.

Deze website maakt gebruik van cookies.  Meer informatie.