Shardul Paricharak
Promovendus / gast
- Naam
- Dr. S.A. Paricharak
- Telefoon
- +31 71 527 4328
- s.a.paricharak@lacdr.leidenuniv.nl
Promovendus / gast
- Wiskunde en Natuurwetenschappen
- Leiden Academic Centre for Drug Research
- LACDR/Medicinal Chemistry
- Paricharak S.A., Méndez-Lucio O., Chavan Ravindranath A., Bender A., IJzerman A.P. & Westen G.J. van (2018), Data-driven approaches used for compound library design, hit triage and bioactivity modeling in high-throughput screening, Briefings in Bioinformatics 19(2): 277-285.
- Paricharak S.A. (9 februari 2017), Transforming data into knowledge for intelligent decision-making in early drug discovery (Dissertatie. Leiden Academic Centre for Drug Research (LACDR), Science, Leiden University). Promotor(en) en copromotor(en): IJzerman A.P., Bender A.
- Mohan C.D., Srinivasa V., Rangappa S., Mervin L., Mohan S., Paricharak S.A., Baday S., Li F., Shanmugam M.K., Chinnathambi A., Zayed M.E., Alharbi S.A., Bender A., Sethi G. & Basappa Rangappa K.S. (2016), Trisubstituted-Imidazoles Induce Apoptosis in Human Breast Cancer Cells by Targeting the Oncogenic PI3K/Akt/mTOR Signaling Pathway, PLoS ONE 11(4): e0153155.
- Paricharak S., IJzerman A.P., Bender A. & Nigsch F. (2016), Analysis of Iterative Screening with Stepwise Compound Selection Based on Novartis In-house HTS Data, ACS Chemical Biology 11: 1255-1264.
- Kumar K.H., Paricharak S., Mohan C.D., Bharathkumar H., Nagabhushana G.P., Rajashekar D.K., Chandrappa G.T., Bender A. & Basappa Rangappa K.S. (2016), Nano-MoO3-mediated synthesis of bioactive thiazolidin-4-ones acting as anti-bacterial agents and their mode-of-action analysis using in silico target prediction, docking and similarity searching, New Journal of Chemistry 40(3): 2189-2199.
- Paricharak S., Cortés-Ciriano I., IJzerman A.P., Malliavin T.E. & Bender A. (2015), Proteochemometric modelling coupled to in silico target prediction:: an integrated approach for the simultaneous prediction of polypharmacology and binding affinity/potency of small molecules, Journal of Cheminformatics 7: 15.
- Anusha S., Baburajeev C.P., Mohan C.D., Mathai J., Rangappa S., Mohan S., Paricharak S., Mervin L., Fuchs J.E., Mahedra M., Bender A. & Basappa Rangappa K.S. (2015), A Nano-MgO and Ionic Liquid-Catalyzed ‘Green’ Synthesis Protocol for the Development of Adamantyl-Imidazolo- Thiadiazoles as Anti-Tuberculosis Agents Targeting Sterol 14α-Demethylase (CYP51), PLoS ONE 10(10): e0139798.
- Neelgundmath M., Dinesh K.R., Mohan C.D., Li F., Dai X., Siveen K.S., Paricharak S., Mason D.J., Fuchs J.E., Sethi G., Bender A., Rangappa K.S., Kotresh O. & Basappa (2015), Novel synthetic coumarins that targets NF-κB in Hepatocellular carcinoma, Bioorganic and Medicinal Chemistry Letters 25: 893-897.
- Koutsoukas A., Paricharak S., Galloway W.R.J.D., Spring D.R., IJzerman A.P., Glen R.C., Marcus D. & Bender A. (2014), How Diverse Are Diversity Assessment Methods? A Comparative Analysis and Benchmarking of Molecular Descriptor Space, Journal of Chemical Information and Modeling 54(1): 230-242.
- Bharathkumar H., Paricharak S., Dinesh K.R., Siveen K.S., Fuchs J.E., Rangappa S., Mohan C.D., Mohandas N., Kumar A.P., Sethi G., Bender A. & Basappa Rangappa K.S. (2014), Synthesis, biological evaluation and in silico and in vitro mode-of-action analysis of novel dihydropyrimidones targeting PPAR-γ, RSC Advances 4: 45143-45146.
- Bharathkumar H., Sundaram M.S., Jagadish S., Paricharak S.A., Hemshekhar M., Mason D., Kemparaju K., Girish K.S., Basappa Bender A. & Rangappa K.S. (2014), Novel Benzoxazine-Based Aglycones Block Glucose Uptake In Vivo by Inhibiting Glycosidases, PLoS ONE 9(7): e102759.
- Paricharak S., Klenka T., Augustin M., Patel U.A. & Bender A. (2013), Are phylogenetic trees suitable for chemogenomics analyses of bioactivity data sets: the importance of shared active compounds and choosing a suitable data embedding method, as exemplified on Kinases, 5(49): 49-68.
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