Patrick Dekker
Onderzoeker/gast
- Naam
- P.M. Dekker Ph.D.
- Telefoon
- 071 5273585
- p.m.dekker@lic.leidenuniv.nl
- ORCID iD
- 0000-0002-4970-0038
Onderzoeker/gast
- LIC
- Chemistry for Human Health/LG
- Bio-organic Synthesis/LG
Onderzoeker
- LIC
- Chemistry for Human Health/LG
- Bio-organic Synthesis/LG
- Dekker P.M., Huber E.M., Maurits E., Wang X., Heinemeyer W., Florea B.I., Groll M. & Overkleeft H.S. (2026), Structure-based design of pan-selective peptide epoxyketones for the three human immunoproteasome active sites, Journal of Medicinal Chemistry 69(2): 1247-1263.
- Miyamoto Y., Hurysz B.M., Fajtova P., Eckmann P., Serafim M.S.M., Kronenberger T., Al-Hindy M., Dekker P.M., Maurits E., Overkleeft H.S, Bergdahl B.M., Almaliti J., Gerwick W.H., O'Donoghue A.J. & Eckmann L. (2025), Inhibitors of the 20S proteasome β5 subunit as potent and selective agents against Trichomonas vaginalis, Antimicrobial Agents and Chemotherapy 69(12): e00893-25.
- Dekker P.M. (28 november 2024), Design of selective inhibitors for human immunoproteasomes (Dissertatie. Leiden Institute of Chemistry (LIC), Faculty of Science, Leiden University). Promotor(en) en copromotor(en): Overkleeft H.S., Florea B.I.
- Maurits E., Graaff M.J. van de, Maiorana S., Wander D.P.A., Dekker P.M., Zanden S.Y. van der, Florea B.I., Neefjes J.J.C., Overkleeft H.S. & Kasteren S.I. van (2020), Immunoproteasome inhibitor-doxorubicin conjugates target multiple myeloma cells and release doxorubicin upon low-dose photon irradiation, Journal of the American Chemical Society 142(16): 7250-7253.