Nicola Wade
Promovendus / gast
- Naam
- Dr. N. Wade
- Telefoon
- +31 71 527 4363
- n.wade@biology.leidenuniv.nl
- ORCID iD
- 0000-0001-6191-4066
Promovendus / gast
- Wiskunde en Natuurwetenschappen
- Instituut Biologie Leiden
- IBL Microbial Sciences
- Wade N. (17 januari 2024), Search and rescue: tackling antibiotic resistance with chemistry (Dissertatie. Institute of Biology Leiden (IBL), Faculty of Science, Leiden University). Promotor(en) en copromotor(en): Martin N.I., Innocenti P.
- Groesen E. van, Mons E., Kotsogianni A.I., Arts M., Tehrani K.H.M.E., Wade N., Lysenko V., Stel F.M., Zwerus J.T., De Benedetti S., Bakker A.T., Chakraborty P., Stelt M. van der, Scheffers D.-J., Gooskens J., Smits W.K., Holden K., Gilmour P., Willemse J.J., Hitchcock C.A., Hasselt J.G.C. van, Schneider T. & Martin N.I. (2024), Semisynthetic guanidino lipoglycopeptides with potent in vitro and in vivo antibacterial activity, Science Translational Medicine 16(759): eabo4736.
- Wade N., Wesseling C.M.J., Innocenti P., Slingerland C.J., Koningstein G.M., Luirink J. & Martin N.I. (2022), Synthesis and structure–activity studies of β-barrel assembly machine complex inhibitor MRL-494, ACS infectious diseases 8(11): 2242-2252.
- Haren M.J. van, Tehrani K.H.M.E., Kotsogianni Teftsoglou A.I., Wade N., Brüchle N.C., Mashayekhi V. & Martin N.I. (2021), Cephalosporin prodrug inhibitors overcome metallo‐β‐lactamase driven antibiotic resistance, Chemistry: a European Journal 27(11): 3806-3811.
- Tehrani K.H.M.E., Wade N., Mashayekhi V., Brüchle N.C., Jespers W., Voskuil K., Pesce D., Haren. M.J. van, Westen G.J.P. van & Martin N.I. (2021), Novel cephalosporin conjugates display potent and selective inhibition of imipenemase-type metallo-β-lactamases, Journal of Medicinal Chemistry 64(13): 9141-9151.
- Wade N., Tehrani K.H.M.E., Brüchle N.C., Haren M.J. van, Mashayekhi Vi. & Martin N.I. (2021), Mechanistic investigations of metallo‐β‐lactamase inhibitors: strong zinc binding Is not required for potent enzyme inhibition, ChemMedChem 16(10): 1651-1659.
- Tehrani K.H.M.E., Wade N., Mashayekhi V., Brüchle N., Jespers W., Voskuil K., Pesce D., Haren M.J. van, Westen G.J.P. van & Martin N.I. (2021), Novel Cephalosporin conjugates display potent and selective inhibition of Imipenemase-type Metallo-β-Lactamases, Journal of Medicinal Chemistry 64(13): 9141–9151.
- Haren M.J. van, Tehrani K.H.M.E., Kotsogianni I., Wade N., Brüchle N., Mashayekhi V. & Martin N.I. (2021), Cephalosporin prodrug inhibitors overcome metallo-β-lactamase driven antibiotic resistance, Chemistry: a European Journal 27(11): 3806-3811.
- Tehrani K.H.M.E., Brüchle N.C., Wade N., Mashayekhi V., Pesce D., Haren M.J. van & Martin N.I. (2020), Small molecule carboxylates inhibit metallo-β-lactamases and resensitize carbapenem-resistant bacteria to meropenem, ACS infectious diseases 6(6): 1366-1371.
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