Marjolein Isendoorn
Gastonderzoeker
- Naam
- Dr. M.M.E. Isendoorn
- Telefoon
- 071 5273576
- m.m.e.isendoorn@lic.leidenuniv.nl
- ORCID iD
- 0000-0002-8076-3766
Gastonderzoeker
- Faculteit der Wiskunde en Natuurwetenschappen
- LIC
- Chemistry for Human Health
- Bio-organic Synthesis
- Isendoorn M.M.E. (2 september 2025), Design and synthesis of immunomodulatory peptide conjugates (Dissertatie. Leiden Institute of Chemistry (LIC), Faculty of Science, Leiden University). Promotor(en): Codée J.D.C. & Filippov D.V.
- Mostert T.P., Kessler A.L., Luijten R.J., Doelman W., Isendoorn M.M.E., Filippov D.V., Kasteren S.I. van & Buschow S.I. (2025), Bioorthogonal click chemistry to visualize an immunogenic HLA-A2-restricted hepatitis B virus epitope in human monocyte-derived dendritic cells, Journal of Immunology : vkaf312.
- Castello G., Isendoorn M.M.E., Camps M., Meeuwenoord N.J., Verhoeks V.F.H., Ende T.C. van den, Codée J.D.C., Ossendorp F. & Filippov D.V. (2025), Solid-Phase Synthesis and Immunological Evaluation of Peptide Conjugates Containing Stereochemically Defined UPam-Based TLR2 Ligands and Epitopes from SARS-CoV-2 Virus, Bioconjugate Chemistry : .
- Doelman W., Ligthart N.A.M., Plassche M.A.T. van de, Geus M.A.R. de, Reinalda L., Isendoorn M.M.E., Filippov D.V. & Kasteren S.I. van (2024), Synthesis of peptides containing a combination of free and 2-trans-cyclooctene carbamate protected lysine residues, ChemBioChem 25(4): e202300786.
- Isendoorn M.M.E., Castello G., Koc C., Meeuwenoord N.J., Codee J.D.C., Ossendorp F. & Filippov D.V. (2024), Mono-Palmitoyl-N-Alkylurea Ligands as specific activators of Human Toll-Like Receptor 2/6 Heterodimer, ChemBioChem 25(23): e202400583.
- Noone D.P., Isendoorn M.M.E., Hamers S.M.W.R., Keizer M.E., Wulffele J., Velden T.T. van der, Dijkstra D.J., Trouw L.A., Filippov D.V. & Sharp T.H. (2024), Structural basis for surface activation of the classical complement cascade by the short pentraxin C- reactive protein, Proceedings of the National Academy of Sciences 121(37): e2404542121.
- Ligthart N.A.M., Geus M.A.R. de, Plassche M.A.T. van de, Torres Garcia D., Isendoorn M.M.E., Reinalda L., Ofman D.E., Leeuwen T. van & Kasteren S.I. van (2023), A lysosome-targeted tetrazine for organelle-specific click-to-release chemistry in antigen presenting cells, Journal of the American Chemical Society 145(23): 12630-12640.
- Tondini E., Reintjens N.R.M., Castello G., Arakelian T., Isendoorn M.M.E., Camps M., Vree J., Marel G.A. van der, Filippov D.V., Codee J.D.C. & Ossendorp F. (2022), Lipid A analog CRX-527 conjugated to synthetic peptides enhances vaccination efficacy and tumor control, npj Vaccines 7: 64.