Brecht Ellenbroek
Promovendus
- Naam
- Mr. B.D. Ellenbroek
- Telefoon
- 071 5274206
- b.d.ellenbroek@lacdr.leidenuniv.nl
- ORCID iD
- 0000-0001-9987-9825
For more information look at the English website
Promovendus
- LACDR
- Divisie Medicinal Chemistry
- Kahler J.P., Ellenbroek B.D., Noord V.E. van der, Water B. van de & Pomplun S.J. (2026), ReCHEMbinant stapling enhances intracellular delivery and bioactivity of engineered protein inhibitors, Chem 12(4): 102839.
- Ellenbroek B.D. (10 juni 2026), The design of transcription factor-based inhibitors to target Myc: drop the Myc! (Dissertatie. Leiden Academic Centre for Drug Research (LACDR), Faculty of Science, Leiden University). Promotor(en) en copromotor(en): Eck M. van & Martin N.I., Pomplun S.J.
- Ellenbroek B.D., Tirtosentono A.S.S. & Pomplun S.J. (2025), AlphaFold-guided discovery of an overlapping MYC/Miz-1 interface enables peptidomimetic disruption of MYC/MAX, ChemMedChem 20(23): e202500740.
- Ellenbroek B.D., Kahler J.P., Evers S.R. & Pomplun S.J. (2024), Synthetic peptides: promising modalities for the targeting of disease-related nucleic acids, Angewandte Chemie (International Edition) 63(20): e202401704.
- Ellenbroek B.D., Kahler J.P., Arella D., Lin C., Jespers W., Züger E.A.K., Drukker M.E. & Pomplun S.J. (2024), Development of DuoMYC: a synthetic cell penetrant miniprotein that efficiently inhibits the oncogenic transcription factor MYC, Angewandte Chemie (International Edition) 64(4): e202416082.