Proefschrift
Inverse design of curvature-sensing antiviral peptides
Viral diseases constitute one of the major challenges in modern medicine. Membrane-targeting have broad-spectrum potential and could distinguish viral membranes from the host cell plasma membrane by the difference in membrane curvature.
- Auteur
- N. van Hilten
- Datum
- 14 september 2023
- Links
- Thesis in Leiden Repository
In this thesis, we used a combination of molecular dynamics simulations and an evolutionary algorithm to inverse design such curvature-sensing antiviral peptides, purely from physical principles.