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Proefschrift

Functional characterization and unraveling the Gene Regulatory Networks (GRNs) of HD-Zip transcription factor HB40 (and HB22) in Arabidopsis thaliana

In this Ph.D. thesis, we characterized two novel upstream regulators of JUB1, HB40, and HB22, in Arabidopsis thaliana. In Chapter 2, we described functions of HB40 in modulating growth and development via the regulation of JUB1 and GA inactivation genes GA2OXs.

Auteur
Dong, S.
Datum
14 mei 2020
Links
Thesis in Leiden Repository

In this Ph.D. thesis, we characterized two novel upstream regulators of JUB1, HB40, and HB22, in Arabidopsis thaliana. In Chapter 2, we described functions of HB40 in modulating growth and development via the regulation of JUB1 and GA inactivation genes GA2OXs. In Chapter 3, we studied whether the HB40-JUB1 regulatory unit plays a role in drought tolerance. Our results suggest that HB40-JUB1 is involved in the modulation of growth, development and drought response. In Chapter 4, we showed that HB40 and its homologues HB21 and HB53 are functionally redundant in repressing hypocotyl elongation under dark conditions. Like HB40, HB21 and HB53 positively and directly regulate the expression of JUB1. In Chapter 5, we investigated the potential gene regulatory network (GRN) controlled by HB22.

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