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Discovery and characterization of new glucosylated metabolites: pathophysiological consequences

Within this thesis the central stage is taken by the discovery and investigation of transglycosylation of sterols. First, investigation focuses on the development of a method to accurately detect and quantify glucosylated metabolites in biological materials.

H.N.J. Meijer
02 november 2023
Thesis in Leiden Repository

Next, the studies concentrate on the formation and occurrence of specific glucosylated metabolites, in particular glucosyl-desmosterol (GlcDesm), glucosyl-7-dehydrocholesterol (Glc7DHC) and glucosylated vitamin D3 (GlcD3).

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