Tyrza van Leeuwen
Project manager/ management & office assistent
- Naam
- Dr. T. van Leeuwen
- Telefoon
- +31 71 527 4292
- t.van.leeuwen@lic.leidenuniv.nl
- ORCID iD
- 0000-0002-8891-2797
Project manager/ management & office assistent
- Wiskunde en Natuurwetenschappen
- Leiden Institute of Chemistry
- LIC/Diensten
- LIC/D/Management & Secretariaten
- Ligthart N.A.M., Geus M.A.R. de, Plassche M.A.T. van de, Torres Garcia D., Isendoorn M.M.E., Reinalda L., Ofman D.E., Leeuwen T. van & Kasteren S.I. van (2023), A lysosome-targeted tetrazine for organelle-specific click-to-release chemistry in antigen presenting cells, Journal of the American Chemical Society 145(23): 12630-12640.
- Leeuwen T. van (23 november 2023), Bioorthogonal chemistry to unveil antigen processing events (Dissertatie. Leiden Institute of Chemistry (LIC), Faculty of Science, Leiden University). Promotor(en): Kasteren S.I. van & Overkleeft H.S.
- Leeuwen T. van, Doelman W., Kieboom R.W.R. van den, Florea B.I. & Kasteren S.I. van (2023), Bioorthogonal peptide enrichment from complex samples using a rink-amide-based catch-and-release strategy, ChemBioChem 24(8): e202300082.
- Torres-Garcia D., Plassche M.A.T. van de, Boven E. van, Leeuwen T. van, Groenewold M.G.J., Sarris A.J.C., Klein L., Overkleeft H.S. & Kasteren S.I. van (2022), Methyltetrazine as a small live-cell compatible bioorthogonal handle for imaging enzyme activities in situ, RSC Chemical Biology 3(11): 1325-1330.
- Dalen F.J. van, Bakkum T., Leeuwen T. van, Groenewold G.J.M., Deu E., Koster A.J., Kasteren S.I. van & Verdoes M. (2021), Application of a highly selective cathepsin S two-step activity-based probe in multicolor bio-orthogonal correlative light-electron microscopy, Frontiers in Chemistry 8: 628433.
- Leeuwen T. van, Araman C., Pournara L.P., Kampstra A.S.B., Bakkum T., Marqvorsen M.H.S., Nascimento C.R., Groenewold G.J.M., Wulp W. van der, Camps M.G.M., Janssen G.M.C., Veelen P.A. van, Westen G.J.P. van Janssen A.P.A., Florea B.I., Overkleeft H.S., Ossendorp F.A., Toes R.E.M. & Kasteren S.I. van (2021), Bioorthogonal protein labelling enables the study of antigen processing of citrullinated and carbamylated auto-antigens, RSC Chemical Biology 2(3): 855-862.
- Bakkum T., Heemskerk M.T., Bos E., Groenewold G.J.M., Oikonomeas-Koppasis N., Walburg K.V., Veen S. van, Lienden M.J.C. van der, Leeuwen T. van, Haks M.C., Ottenhoff T.H.M., Koster A.J. & Kasteren S.I. van (2020), Bioorthogonal correlative light-electron microscopy of mycobacterium tuberculosis in macrophages reveals the effect of antituberculosis drugs on subcellular bacterial distribution, ACS Central Science 6(11): 1997-2007.
- Bakkum T., Leeuwen T. van, Sarris A.J.C., Elsland D.M. van, Poulcharidis D., Overkleeft H.S. & Kasteren S.I. van (2018), Quantification of Bioorthogonal Stability in Immune Phagocytes Using Flow Cytometry Reveals Rapid Degradation of Strained Alkynes, ACS Chemical Biology 13(5): 1173-1179.