Universiteit Leiden

nl en

Theodorus van Berkel

Emeritus hoogleraar Biofarmacie in het bijzonder de drug targeting

Naam
Prof.dr. T.J.C. van Berkel
Telefoon
+31 71 527 2727
E-mail
t.berkel@lacdr.leidenuniv.nl

Emeritus hoogleraar Biofarmacie in het bijzonder de drug targeting

  • Wiskunde en Natuurwetenschappen
  • Leiden Academic Centre for Drug Research
  • LACDR/Biopharmaceutics
  • Hoekstra M. & Berkel T.J.C. van (2016), Functionality of High-Density Lipoprotein as Antiatherosclerotic Therapeutic Target, ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY 36(11): E87-E94.artikel in tijdschrift (refereed)
  • Louwe M.C., Lammers B., Frias M.A., Foks A.C., Leeuw L.R. de, Hildebrand R.B., Kuiper J., Smit J.W.A., Berkel T.J.C.van, James R.W., Geerling J.J., Rensen P.C.N. & Eck M. van (2016), ABCA1 deficiency protects the heart against myocardial infarction-induced injury, Atherosclerosis 2016(251): 159-163.artikel in tijdschrift (refereed)
  • Medina I., Cougoule C., Drechsler M., Bermudez B., Koenen R.R., Sluimer J., Wolfs I., Döring Y., Herias V., Gijbels M., Bot I., de Jager S.C., Weber C., Cleutjens J., van Berkel T.J.C., Sikkink K.J., Mócsai A., Maridonneau-Parini I., Soehnlein O. & Biessen E.A. (2015), Hck/Fgr Kinase Deficiency Reduces Plaque Growth and Stability by Blunting Monocyte Recruitment and Intraplaque Motility, Circulation 132(6): 490-501.artikel in tijdschrift (refereed)
  • Kampen E. van, Beaslas O., Hildebrand R.B., Lammers B., Berkel T.J.C. van, Olkkonen V.M. & Eck M. van (2014), Orp8 Deficiency in Bone Marrow-Derived Cells Reduces Atherosclerotic Lesion Progression in LDL Receptor Knockout Mice, PLoS ONE 9(10): e109024.artikel in tijdschrift (refereed)
  • Bot I., Daissormont I.T., Zernecke A., Puijvelde G.H.M. van, Kramp B., Jager S.C. de, Sluimer J.C., Manca M., Hérias V., Westra M.M., Bot M., Santbrink P.J. van, Berkel T.J.C. van, Su L., Skjelland M., Gullestad L., Kuiper J., Halvorsen B., Aukrust P., Koenen R.R., Weber C. & Biessen E.A. (2014), CXCR4 blockade induces atherosclerosis by affecting neutrophil function, Journal of Molecular and Cellular Cardiology 74: 44-52.artikel in tijdschrift (refereed)
  • Stoep M. van der, Li Z., Sluis R.J. van der, Berkel T.J.C. van, Eck M. van, Hoekstra M. & Korporaal S.J.A. (2013), Liver X receptor (LXR) activation influences murine platelet count only under normolipidemic conditions, Journal of Thrombosis and Haemostasis 11: 910-910.artikel in tijdschrift (refereed)
  • Van der Stoep M., Li Z., Calpe-Berdiel L., Van der Sluis R. J., McKinnon H. J., Smit M. J., Van Berkel T. J. C., Van Eck M., Hoekstra M. & Korporaal S. J. A. (2013), Liver X receptor (LXR) agonist T0901317 induces regression of early and advanced atherosclerotic lesions under normolipidemic conditions in mice Journal of Thrombosis and Haemostasis. 520-520.congresbijdrage (refereed)
  • Bot M., Jager S.C., MacAleese L., Lagraauw H.M., Berkel T.J., Quax P.H., Kuiper J., Heeren R.M., Biessen E.A. & Bot I. (2013), Lysophosphatidic acid triggers mast cell-driven atherosclerotic plaque destabilization by increasing vascular inflammation., Journal of lipid research 54(5): 1265-74.artikel in tijdschrift (refereed)
  • Vrins C.L.J., Ottenhoff R., Oever K. van den, Waart D.R. de, Kruyt J.K., Zhao Y., Berkel T.J.C. van, Havekes L.M., Aerts J.M., Eck M. van, Rensen P.C.N. & Groen A.K. (2012), Trans-intestinal cholesterol efflux is not mediated through high density lipoprotein, Journal of lipid research 53(10): 2017-2023.artikel in tijdschrift (refereed)
  • Hoekstra M., Sluis R.J. van der, Li Z., Oosterveer M.H., Groen A.K. & Berkel T.J.C. van (2012), FXR agonist GW4064 increases plasma glucocorticoid levels in C57BL/6 mice, MOLECULAR AND CELLULAR ENDOCRINOLOGY 362(1-2): 69-75.artikel in tijdschrift (refereed)
  • Bot I., Vries H. de, Korporaal S.J.A., Foks A.C., Bot M., Veldhoven J.P.D, Borg M.N. D. ter, Santbrink P.J. van, Berkel T.J. van. C., Kuiper J. & Ijzerman A.P. (2012), Adenosine A(2B) Receptor Agonism Inhibits Neointimal Lesion Development After Arterial Injury in Apolipoprotein E-Deficient Mice, ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY 32(9): 2197-2205.artikel in tijdschrift (refereed)
  • Li Z., Wang Y., Sluis R.J. van der, Hoorn J.W.A. van der, Princen H.M.G., Eck M. van, Berkel T.J.C. van, Rensen P.C.N. & Hoekstra M. (2012), Niacin reduces plasma CETP levels by diminishing liver macrophage content in CETP transgenic mice, Biochemical Pharmacology 84(6): 821-829.artikel in tijdschrift (refereed)
  • Calpe-Berdiel L., Zhao Y., Graauw M. de, Ye D., Santbrink P.J. van, Mommaas A.M., Foks A., Bot M., Meurs I., Kuiper J., Mack J.T., Eck M. van, Tew K.D. & Berkel T.J.C. van (2012), Macrophage ABCA2 deletion modulates intracellular cholesterol deposition, affects macrophage apoptosis, and decreases early atherosclerosis in LDL receptor knockout mice, Atherosclerosis 223(2): 332-341.artikel in tijdschrift (refereed)
  • Calpe-Berdiel L., Zhao Y., Graauw M. de, Ye D., Santbrink P.J. van, Mommaas A.M., Foks A.C., Bot M., Meurs I., Kuiper J., Mack J.T., Eck M. van, Tew K.D. & Berkel T.J.C. van (2012), Macrophage ABCA2 deletion modulates intracellular cholesterol deposition, affects macrophage apoptosis, and decreases early atherosclerosis in LDL receptor knockout mice, Atherosclerosis 223(2): 332-341.artikel in tijdschrift (refereed)
  • Sluis R.J. van der, Puijvelde G.H.M. van, Berkel T.J.C. van & Hoekstra M. (2012), Adrenalectomy stimulates the formation of initial atherosclerotic lesions: reversal by adrenal transplantation, Atherosclerosis 221(1): 76-83.artikel in tijdschrift (refereed)
  • Meurs I., Lammers B., Zhao Y., Out R., Hildebrand R.B., Hoekstra M., Berkel T.J.C. van & Eck M. van (2012), The effect of ABCG1 deficiency on atherosclerotic lesion development in LDL receptor knockout mice depends on the stage of atherogenesis, Atherosclerosis 221(1): 41-47.artikel in tijdschrift (refereed)
  • Berkel T.J.C. van (25 maart 2011), Met Hartstocht voor de Va(ar)ten (Lezing). Leiden.overig
  • Hu L., Hoogt C.C. van der, Espirito Santo S.M.S., Out R., Kypreos K.E., Vlijmen B.L. van, Berkel T.J.C. van, Romijn J.A., Havekes L.M., Willems van Dijk K. & Rensen P.C.N. (2008), The hepatic uptake of VLDL in absence off the three major apoE-recognizing receptors is regulated by LPL activity and involves heparan sulfate proteoglycans and scavenger receptor BI, Journal of Lipid Research.artikel in tijdschrift (refereed)
  • Hoekstra M., Meurs I., Koenders M., Out R., Hildebrand R.B., Kruijt J.K., Eck M. van & Berkel T.J.C. van (2008), Absence of HDL cholesteryl ester uptake in mice via SR-BI impairs an adequate adrenalglucocorticoid-mediated stress resose to fasting, Journal of Lipid Research 49: 738-745.artikel in tijdschrift (refereed)
  • Wanrooij E.J.A. van, Jager S.C.A. de, Es T. van, Vos P, Birch H.L., Owen D.A., Watson R.J., Biessen E.A.L., Chapman G.A. & Berkel T.J.C. van (2008), CXCR3 antagonist NBI-74330 attenuates atherosclerotic plaque formation in LDL receoptor-deficient mice, Arteriosclerosis, Thrombosis and Vascular Biology 28: 251-257.artikel in tijdschrift (refereed)
  • Out R., Hoekstra M., Habets K.L., Meurs I., Waard V. de, Hildebrand R.B., Wang Y., Chimini G., Kuiper J., Berkel T.J.C. van & Eck M. van (2008), Combined deletion of macrophage ABCA1 and ABCG1 leads to massive lipid accumulation in tissue macrophagesand distinct atherosclerosis at relatively low plasma cholesterol levels, Arteriosclerosis, Thrombosis and Vascular Biology 28: 258-264.artikel in tijdschrift (refereed)
  • Eck M. van, Hoekstra M., Out R., Ros I.X., Kruijt J.K., Hildebrand R.B. & Berkel T.J.C. van (2008), Scavenger receptor BI facilitates the metabolism of VLDL lipoproteins in vivo, Journal of Lipid Research 49(1): 136-146.artikel in tijdschrift (refereed)
  • Guo J., Bot I., Nooijer R. de, Hoffman S.J., Stroup G.B., Biessen E.A.L., Benson G.M., Groot P.H., Eck M. van & Berkel T.J.C. van (2008), Leukocyte cathepsin K affects atherosclerotic lesion composition and bone mineral density in LDL-receptor deficient mice, Cardiovascular Research.artikel in tijdschrift (refereed)
  • Hauer A.D., Habets K.L., Wanrooij E.J.A. van, Vos P. de, Krueger J., Reisfeld R.A., Berkel T.J.C. van & Kuiper J. (2008), Vaccination against TIE2 reduces atherosclerosis, Atherosclerosis.artikel in tijdschrift (refereed)
  • Haan W. de, Out R., Berbée J.F., Hoogt C.C. van der, Dijk K.W. van, Berkel T.J.C. van, Romijn J.A., Havekes L.M. & Rensen P.C.N. (2008), Apolipoprotein CI inhibits scavenger receptor BI and increases plasma HDL levels in vivo, Biochemical and Biophysical Research Communications 377(4): 1294-1298.artikel in tijdschrift (refereed)
  • Ye D., Kraaijeveld A.O., Grauss R.W., Willems S.M., Vark-van der Zee L.C. van, Jager S.C.A. de, Jauhiainen M., Kuivenhoven J.A., Dalling-Thie G.M., Atsma D.E., Hogendoorn P.C., Biessen E.A.L., Berkel T.J.C. van, Jukema J.W. & Eck M. van (2008), Reduced leucocyte cholesteryl ester transfer protein expression in acute coronary syndromes, Journal of Internal Medicine 264(6): 571-585.artikel in tijdschrift (refereed)
  • Jager S.C.A. de, Kraaijeveld A.O., Grauss R.W., Jager W. de, Liem S.S., Hoeven B.L. van der, Prakken B.J., Putter H., Berkel T.J.C. van, Atsma D.E., Schalij M.J., Jukema J.W. & Biessen E.A.L. (2008), CCL3 (MIP-1alpha) levels are elevated during acute coronary syndromes and show strong prognostic power for future ischemic events, Journal of Molecular and Cellular Cardiology 45(3): 446-452.artikel in tijdschrift (refereed)
  • Hu L., Hoogt C.C. van der, Espirito Santo S.M.S., Out R., Kypreos K.E., Vlijmen B.J.M. van, Berkel T.J.C. van, Romijn J.A., Havekes L.M., Dijk K.W. van & Rensen P.C.N. (2008), The hepatic uptake of VLDL in lrp-ldlr-/-vldlr-/- mice is regulated by LPL, Journal of Lipid Research 49(7): 1553-1561.artikel in tijdschrift (refereed)
  • Wanrooij E.J.A. van, Vos P. de, Bixel M.G., Vestweber D., Berkel T.J.C. van & Kuiper J. (2008), Vaccination against CD99 inhibits atherogenesis in low-density lipoprotein, Cardiovascular Research 78(3): 590-596.artikel in tijdschrift (refereed)
  • Hoekstra M., Meurs I., Koenders M., Out R., Hildebrand R.B., Kruijt J.K., Eck M. van & Berkel T.J.C. van (2008), Absence of HDL cholesteryl ester uptake in mice via SR-BI impairs an adequate, Journal of Lipid Research 49(4): 738-745.artikel in tijdschrift (refereed)
  • Wanrooij E.J.A. van, Jager S.C.A. de, Es T. van, Vos P. de, Birch H.L., Owen D.A., Watson R.J., Biessen E.A.L., Chapman G.A., Berkel T.J.C. van & Kuiper J. (2008), CXCR3 antagonist NBI-74330 attenuates atherosclerotic plaque formation in LDL, Arterioscler.Thromb Vasc Biol. 28(2): 251-257.artikel in tijdschrift (refereed)
  • Out R., Hoekstra M., Habets K., Meurs I., Waard V. de, Hildebrand R.B., Wang Y., Chimini G., Kuiper J., Berkel T.J.C. van & Eck M. van (2008), Combined deletion of macrophage ABCA1 and ABCG1 leads to massive lipid accumulation in tissue macrophages and distinct atherosclerosis at relatively low, Arterioscler.Thromb Vasc Biol. 28(2): 258-264.artikel in tijdschrift (refereed)
  • Out R., Jessup W., Goff L.J., Hoekstra M., Gelissen I.C., Zhao Y., Kritharides L., Chimini G., Kuiper J., Chapman M.J., Huby T., Berkel T.J.C. van & Eck M. van (2008), Coexistence of foam cells and hypocholesterolemia in mice lacking the ABC, Circulation Research 102(1): 113-120.artikel in tijdschrift (refereed)
  • Hawinkels L.J.A.C., Rossenberg S.M.W. van, Jonge-Muller E.S.M. de, Molenaar T.J.M., Appeldoorn C.C.M., Berkel T.J.C. van, Sier C.F.M. & Biessen E.A.L. (2007), Efficient degradation-aided selection of protease inhibitors by phage display, Biochemical and Biophysical Research Communications 364(3): 549-555.artikel in tijdschrift (refereed)
  • Lucerna M., Zernecke A., Nooijer R. de, Jager S.C.A. de, Bot I., Lans C. van der, Kholova I, Liehn E.A., Berkel T.J.C. van, Yla-Herttuala S., Weber C. & Biessen E.A.L. (2007), Vascular endothelial growth factor-A induces plaque expansion in Apo Eknockout mice by promoting de novo leukocyte recruitment, Blood 109: 122-129.artikel in tijdschrift (refereed)
  • Yu H., Sliedregt-Bol K.M., Overkleeft H.S., Marel G.A. van der, Berkel T.J.C. van & Biessen E.A.L. (2007), Therapeutic potential of a synthetic peptide inhibitor of nuclear factor of activated T cells as antirestenotic agent, Arteriosclerosis, Thrombosis and Vascular Biology 26(7): 1531-1537.artikel in tijdschrift (refereed)
  • Triesscheijn M., Ruevekamp M., Out R., Berkel T.J.C. van, Schellens J.H., Baas P. & Stewart F.A. (2007), The pharmacokinetic behavior of the photosensitizer meso-tetra-hydroxyphenyl-chlorin in mice and men, Cancer Chemotherapy and Pharmacology 60: 113-122.artikel in tijdschrift (refereed)
  • Kraaijeveld A.O., Jager S.C.A. de, Jager W.J. de, Prakken B.J., McColl S.R., Haspels I, Putter H., Berkel T.J.C. van, Nagelkerken L., Jukema J.W. & Biessen E.A.L. (2007), CC Chemokine Ligand-5 (CCL5/RANTES) and CC Chemokine Ligand-18 (CCL18/PARC) Are Specific Markers of Refractory Unstable Angina Pectoris and Are Transiently Raised During Severe Ischemic Symptoms, Circulation 116: 1931-1941.artikel in tijdschrift (refereed)
  • Westerterp M., Eck M. van, Haan W. de, Offerman E.H., Berkel T.J.C. van, Havekes L.M. & Rensen P.C.N. (2007), Apolipoprotein CI aggravates atherosclerosis development in apoE-knockout mice despite mediating cholesterol efflux from macrophages., Atherosclerosis 195(1): E9-E16.artikel in tijdschrift (refereed)
  • Eck M. van, Ye D., Hildebrand R.B., Kruijt J.K., Haan W. de, Hoekstra M., Rensen P.C.N., Ehnholm C., Jauhiainen M. & Berkel T.J.C. van (2007), Important role for bone marrow-derived cholesteryl ester transfer protein in lipoprotein cholesterol redistribution and atherosclerotic lesion development in LDL receptor knockout mice., Circulation Research 100: 678-685.artikel in tijdschrift (refereed)
  • Vikstedt R., Ye D., Metso J, Hildebrand R.B., Berkel T.J.C. van, Ehnholm C., Jauhiainen M. & Eck M. van (2007), Macrophage phospholipid transfer protein contributes significantly to total plasma phospholipid transfer activity and its deficiency leads to diminished atherosclerotic lesion development, Arteriosclerosis, Thrombosis and Vascular Biology 27: 578-586.artikel in tijdschrift (refereed)
  • Out R., Hoekstra M., Meurs I., Vos P. de, Kuiper J., Eck M. van & Berkel T.J.C. van (2007), Total body ABCG1 expression protects against early atherosclerotic lesion development in mice, Arteriosclerosis, Thrombosis and Vascular Biology 27: 594-599.artikel in tijdschrift (refereed)
  • Fledderus J.O., Thienen J.V. van, Boon R.A., Dekker R.J., Rohlena J., Volger O.L., Bijnen A.B., Daemen M.J., Kuiper J., Berkel T.J.C. van, Pannekoek H. & Horrevoets A.J.G. (2007), Prolonged shear stress and KLF2 suppress constitutive proinflammatory transcription through inhibition of ATF2, Blood 109: 4249-4257.artikel in tijdschrift (refereed)
  • Nofer J.R., Bot M., Brodde M., Taylor P.J., Salm P.H., Brinkmann V., Berkel T.J.C. van, Assmann G. & Biessen E.A.L. (2007), FTY720, a synthetic sphingosine 1 phosphate analogue, inhibits development of atherosclerosis in low-density lipoprotein receptor-deficient mice, Circulation 115: 501-508.artikel in tijdschrift (refereed)
  • Bot I., Jager S.C.A. de, Zernecke A., Lindstedt K, Berkel T.J.C. van, Weber C. & Biessen E.A.L. (2007), Perivascular mast cells promote atherogenesis and induce plaque destabilization in apolipoprotein E-deficient mice, Circulation 115: 2516-2525.artikel in tijdschrift (refereed)
  • Volger O.L., Fledderus J.O., Kisters N., Fontijn R.D., Moerland P.D., Kuiper J., Berkel T.J.C. van, Bijnens A.P., Daemen M.J., Pannekoek H. & Horrevoets A.J.G. (2007), Distinctive expression of chemokines and transforming growth factor-β signaling in human arterial endothelium during atherosclerosis, American Journal of Pathology 171: 326-337.artikel in tijdschrift (refereed)
  • Herczenik E., Bouma B., Korporaal S.J.A., Strangi R., Zeng Q., Gros P., Eck M. van, Berkel T.J.C. van, Gebbink M.F. & Akkerman J.W. (2007), Activation of human platelets by misfolded proteins, Arteriosclerosis, Thrombosis and Vascular Biology 27: 1657-1665.artikel in tijdschrift (refereed)
  • Pennings M., Hildebrand R.B., Ye D., Kunne C., Berkel T.J.C. van, Groen A.K. & Eck M. van (2007), Bone marrow-derived multidrug resistance protein ABCB4 protects against atherosclerotic lesion development in LDL receptor knockout mice, Cardiovascular Research 76: 175-183.artikel in tijdschrift (refereed)
  • Yu H., Berkel T.J.C. van & Biessen E.A.L. (2007), Therapeutic potential of VIVIT, a selective peptide inhibitor of nuclear factor of activated T cells, in cardiovascular disorders, Cardiovascular Drugs and Therapy 25: 175-187.artikel in tijdschrift (refereed)
  • Hauer A.D., Puijvelde G.H.M. van, Peterse N., Vos P. de, Weel V. van, Wanrooij E.J.A. van, Biessen E.A.L., Quax P.H., Niethammer A.G., Reisfeld R.A., Berkel T.J.C. van & Kuiper J. (2007), Vaccination against VEGFR2 attenuates initiation and progression of atherosclerosis, Arteriosclerosis, Thrombosis and Vascular Biology 27: 2050-2057.artikel in tijdschrift (refereed)
  • Kraaieveld A.O., Jager S.C.A. de, Jager W.J. de, Prakken B.J., McColl S.R., Haspels I, Putter H., Berkel T.J.C. van, Nagelkerken L., Jukema J.W. & Biessen E.A.L. (2007), CC chemokine ligand-5 (CCL5/RANTES) and CC chemokine ligand-18 (CCL18/PARC) are specific markers of refractory unstable angina pectoris and are transiently raised during severe ischemic symptoms, Circulation 116: 1931-1941.artikel in tijdschrift (refereed)
  • Puijvelde G.H.M. van, Es T. van, Wanrooij E.J.A. van, Habets K.L., Vos P. de, Zee R. van der, Eden W. van, Berkel T.J.C. van & Kuiper J. (2007), Induction of oral tolerance to HSP60 or an HSP60-peptide activates T cell regulation and reduces atherosclerosis, Arteriosclerosis, Thrombosis and Vascular Biology 27: 2677-2683.artikel in tijdschrift (refereed)
  • Kuiper J., Puijvelde G.H.M. van, Wanrooij E.J.A. van, Es T. van, Habets K.L., Hauer A.D. & Berkel T.J.C. van (2007), Immunomodulation of the inflammatory response in atherosclerosis, Current Opinion in Lipidology 18: 521-526.artikel in tijdschrift (refereed)
  • Korporaal S.J.A., Eck M. van, Adelmeijer J., Ijsseldijk M.J., Out R., Lisman T., Lenting P.J., Berkel T.J.C. van & Akkerman J.W. (2007), Platelet activation by oxidized low density lipoprotein is mediated by CD36 and scavenger receptor-A, Arteriosclerosis, Thrombosis and Vascular Biology 27: 2476-2483.artikel in tijdschrift (refereed)
  • Bot I., Berkel T.J.C. van & Biessen E.A.L. (2007), Viral serine protease inhibitors as anti-atherosclerotic therapy, Current Opinion in Investigational Drugs 8: 729-735.artikel in tijdschrift (refereed)
  • Eck M. van, Hoekstra M., Hildebrand R.B., Yaong Y., Stengel D., Kruijt J.K., Sattler W., Tietge U.J., Ninio E., Berkel T.J.C. van & Praticò D. (2007), Increased oxidative stress in scavenger receptor BI knockout mice with dysfunctional HDL, Arteriosclerosis, Thrombosis and Vascular Biology 27: 2413-2419.artikel in tijdschrift (refereed)
  • Rensen P.C.N., Sliedregt L.A.J.M., Santbrink P.J. van, Ferns M., Schifferstein H.N.J., Leeuwen S.H., Souverijn J.H.M., Berkel T.J.C. van & Biessen E.A.L. (2006), Stimulation of liver-directed cholesterol flux in mice by novel N-acetylgalactosamine-terminated glycolipids with high affinity for the asialoglycoprotein receptor., Arteriosclerosis, Thrombosis and Vascular Biology 26: 169-175.artikel in tijdschrift (refereed)
  • Rensen P.C., Sliedregt L.A.J.M., Santbrink P.J. van, Ferns M., Schifferstein H.N.J., Leeuwen S.H., Souverein J.H., Berkel T.J.C. van & Biessen E.A. (2006), Stimulation of liver-directed cholesterol flux in mice by novel N-acetylgalactosamine-terminated glycolipids with high affinity for the asialoglycoprotein receptor., Arteriosclerosis, Thrombosis and Vascular Biology.artikel in tijdschrift (refereed)
  • Rensen P.C.N., Sliedregt L.A.J.M., Santbrink P.J. van, Ferns M., Schifferstein H.N.J., Leeuwen SH van, Souverijn J.H.M., Berkel T.J.C. van & Biessen E.A.L. (2006), Stimulation of liver-directed cholesterol flux in mice by novel N-acetylgalactosamine-terminated glycolipids with high affinity for the asialoglycoprotein receptor., Arteriosclerosis, Thrombosis and Vascular Biology 26: 169-175.artikel in tijdschrift (refereed)
  • Rensen P.C.N., Gras J.C.E., Lindfors EK, Willems van Dijk K., Jukema J.W., Berkel T.J.C. van & Biessen E.A.L. (2006), Selective targeting of liposomes to macrophages using a ligand with high affinity for the macrophage scavenger receptor class A., Current drug discovery technologies 3: 135-144.artikel in tijdschrift (refereed)
  • Nooijer R. de, Verkleij C.J.N., Thüsen J.H. von der, Jukema J.W., Wall E.E. van der, Berkel T.J.C. van, Baker A.H. & Biessen E.A.L. (2006), Lesional Overexpression of Matrix Metalloproteinase-9 Promotes Intraplaque Hemorrhage in Advanced Lesions But Not at Earlier Stages of Atherogenesis, Arteriosclerosis, Thrombosis and Vascular Biology 26: 340-346.artikel in tijdschrift (refereed)
  • Snoey J., Mertens G., Lievens J., Berkel T.J.C. van, Collen D., Biessen E.A.L. & Geest B. van der (2006), Lipid Emulsions Potently Increase Transgene Expression in Hepatocytes after Adenoviral Transfer, Molecular Therapy 13: 98-107.artikel in tijdschrift (refereed)
  • Hauer A.D., Vos P. de, Peterse N., Cate H. ten, Berkel T.J.C. van, Stassen F.R. & Kuiper J. (2006), Delivery of Chlamydia pneumoniae to the vessel wall aggravates atherosclerosis in LDLr(-/-) mice, Cardiovascular Research 69: 280-288.artikel in tijdschrift (refereed)
  • Kruit J.K., Groen A.K., Berkel T.J.C. van & Kuipers F. (2006), Emerging roles of the intestine in control of cholesterol metabolism, World Journal of Gastroenterology 28: 6429-6439.artikel in tijdschrift (refereed)
  • Wanrooij E.J.A. van, Puijvelde G.H.M. van, Vos P. de, Yagita H., Berkel T.J.C. van & Kuiper J. (2006), Interruption of the Tnfrsf4/Tnfsf4 (OX40/OX40L) pathway attenuates atherogenesis in low-density lipoprotein receptor-deficient mice, Arteriosclerosis, Thrombosis and Vascular Biology.artikel in tijdschrift (refereed)
  • Puijvelde G.H.M. van, Hauer A.D., Vos P. de, Heuvel R. van den, Herwijnen M.J., Zee R. van der, Eden W. van, Berkel T.J.C. van & Kuiper J. (2006), Induction of oral tolerance to oxidized low-density lipoprotein ameliorates atherosclerosis, Circulation 31: 1968-1976.artikel in tijdschrift (refereed)
  • Singaraja R., Eck M. van, Bissada N., Zimetti F., Collins H.L., Hildebrand RB, Hayden A., Brunham L.R., Kang M.H., Fruchart JC, Berkel T.J.C. van, Parks J.S., Staels B., Rothblat G.H., Fievet C. & Hayden M.R. (2006), Both hepatic and extrahepatic ABCA1 have discrete and essential functions in the maintenance of plasma high-density lipoprotein cholesterol levels in vivo, Circulation 19: 1301-1309.artikel in tijdschrift (refereed)
  • Pennings M., Meurs I., Ye D., Out R., Hoekstra M., Berkel T.J.C. van & Eck M. van (2006), Regulation of cholesterol homeostasis in macrophages and consequences for atherosclerotic lesion development, Febs Letters 580: 5588-5596.artikel in tijdschrift (refereed)
  • Hoekstra M., Stitzinger M., Wanrooij E.J.A. van, Michon I.N., Kruijt J.K., Kamphorst J.T., Eck M. van, Vreugdenhil E., Berkel T.J.C. van & Kuiper J. (2006), Microarray analysis indicates an important role for FABP5 and putative novel FABPs on a Western-type diet, Journal of Lipid Research 47: 2198-2207.artikel in tijdschrift (refereed)
  • Out R., Hoekstra M., Hildebrand RB, Kruit J.K., Meurs I., Li Z., Kuipers F., Berkel T.J.C. van & Eck M. van (2006), Macrophage ABCG1 deletion disrupts lipid homeostasis in alveolar macrophages and moderately influences atherosclerotic lesion development in LDL receptor-deficient mice, Arteriosclerosis, Thrombosis and Vascular Biology 26: 2295-2300.artikel in tijdschrift (refereed)
  • Vikstedt R., Ye D., Metso J, Hildebrand RB, Berkel T.J.C. van, Ehnholm C., Jauhiainen M. & Eck M. van (2006), Macrophage PLTP contributes significantly to total plasma phospholipid transfer activity and its deficiency leads to diminished atherosclerotic lesion development, Arteriosclerosis, Thrombosis and Vascular Biology.artikel in tijdschrift (refereed)
  • Gras J.C.E., Verkuijlen P., Frants R.R., Havekes L.M., Berkel T.J.C. van, Biessen E.A.L. & Dijk K.W. van (2006), Specific and efficient targeting of adenovirus vectors to macrophages: Application of a fusion protein between an adenovirus-binding fragment and avidin, linked to a biotinylated oligonucleotide, Journal of Gene Medicine 8(6): 668-678.artikel in tijdschrift (refereed)
  • Nooijer R. de, Verkleij C.J.N., Thusen J.H. von der, Jukema J.W., Wall E.E. van der, Berkel T.J.C. van, Baker A.H. & Biessen E.A.L. (2006), Lesional overexpression of matrix metalloproteinase-9 promotes intraplaque hemorrhage in advanced lesions but not at earlier stages of atherogenesis, Arteriosclerosis, Thrombosis and Vascular Biology 26(2): 340-346.artikel in tijdschrift (refereed)
  • Eck M. van, Singaraja R., Ye D., Hildebrand R.B., James E.R., Hayden M.R. & Berkel T.J.C. van (2006), Macrophage ATP-binding cassette transporter A1 overexpression inhibits atherosclerotic lesion progression in low-density lipoprotein receptor knockout mice, Arterioscler.Thromb.Vasc.Biol. 26: 929-954.artikel in tijdschrift (refereed)
  • Zadelaar A.S.M., Thusen J.H. von der, Boesten L.S.M., Hoeben R.C., Kockx M.M., Versnel M.A., Berkel T.J.C. van, Havekes L.M., Biessen E.A.L. & Vlijmen B.J.M. van (2005), Increased vulnerability of pre-existing atherosclerosis in ApoE-deficient mice following adenovirus-mediated Fas ligand gene transfer, Atherosclerosis 183: 244-250.artikel in tijdschrift (refereed)
  • Zadelaar A.S.M., Thusen J.H. von der, Boesten LS, Hoeben R.C., Kockx M.M., Versnel M.A., Berkel T.J.C. van, Havekes L.M., Biessen E.A. & Vlijmen B.J.M. van (2005), Increased vulnerability of pre-existing atherosclerosis in ApoE-deficient mice following adenovirus mediated Fas ligand gene transfer., Atherosclerosis 183(2): 244-250.artikel in tijdschrift (refereed)
  • Nooijer R. de, Verkleij C.J.N., Thusen J.H. von der, Jukema J.W., Wall E.E. van der, Berkel T.J.C. van, Baker A.H. & Biessen E.A. (2005), Lesional overexpression of matrix metalloproteinase-9 promotes intraplaque hemorrhage in advanced lesions but not at earlier stages of atherogenesis., Arteriosclerosis, Thrombosis and Vascular Biology 26(2): 340-346.artikel in tijdschrift (refereed)
  • Zadelaar A.S.M., Thusen J.H. von der, Boesten L.S.M., Hoeben R.C., Kockx M.M., Versnel M.A., Berkel T.J.C. van, Havekes L.M., Biessen E.A.L. & Vlijmen B.J.M. van (2005), Increased vulnerability of pre-existing atherosclerosis in ApoE-deficient mice following adenovirus-mediated Fas ligand gene transfer., Atherosclerosis 183(2): 244-250.artikel in tijdschrift (refereed)
  • Krom Y.D., Gras J.C.E., Frants R.R., Havekes L.M., Berkel T.J.C. van, Biessen E.A.L. & Willems van Dijk K. (2005), Efficient targeting of adenoviral vectors to integrin positive vascular cells utilizing a CAR-cyclic RGD linker protein., Biochemical and Biophysical Research Communications 338: 847-854.artikel in tijdschrift (refereed)
  • Eck M. van, Oost J., Goudriaan J.R., Hoekstra M., Hildebrand M., Bos IST, Willems van Dijk K. & Berkel T.J.C. van (2005), Role of the macrophage very-low-density lipoprotein receptor in atherosclerotic lesion development., Atherosclerosis 83: 230-237.artikel in tijdschrift (refereed)
  • Krom Y.D., Gras J.C.E., Frants R.R., Havekes L.M., Berkel T.J.C. van, Biessen E.A. & Willems Van Dijk J.A.P. (2005), Efficient targeting of adenoviral vectors to integrin positive vascular cells utilizing a CAR-cyclic RGD linker protein., Biochemical Biophysical Research Communications 338: 847-854.artikel in tijdschrift (refereed)
  • Eck MV, Oost J., Goudriaan J.R., Hoekstra M, Hildebrand RB, Bos IS, Willems Van Dijk J.A.P. & Berkel T.J.C. van (2005), Role of the macrophage very-low-density lipoprotein receptor in atherosclerotic lesion development., Atherosclerosis 183: 230-237.artikel in tijdschrift (refereed)
  • Krom Y.D., Gras J.C.E., Frants R.R., Havekes L.M., Berkel T.J.C. van, Biessen E.A.L. & Willems van Dijk K. (2005), Efficient targeting of adenoviral vectors to integrin positive vascular cells utilizing a CAR-cyclic RGD linker protein., Biochemical and Biophysical Research Communications 338: 847-854.artikel in tijdschrift (refereed)
  • Meurs I., Hoekstra M., Wanrooij E.J.A. van, Hildebrand RB, Kuiper J., Kuipers F., Hardeman M.R., Berkel T.J.C. van & Eck M. van (2005), HDL cholesterol levels are an important factor for determining the lifespan of erythrocytes, Experimental Hematology 33: 1309-1319.artikel in tijdschrift
  • Wanrooij E.J.A. van, Happe H., Hauer A.D., Vos P, Imanishi T., Fujiwara H., Berkel T.J.C. van & Kuiper J. (2005), HIV Entry Inhibitor TAK-779 Attenuates Atherogenesis in Low-Density Lipoprotein Receptor-Deficient Mice, Arteriosclerosis, Thrombosis and Vascular Biology 25: 2642-2647.artikel in tijdschrift
  • Berkel T.J.C. van, Out R., Hoekstra M., Kuiper J., Biessen E.A.L. & Eck M. van (2005), Scavenger receptors: friend or foe in atherosclerosis?, Current Opinion in Lipidology 16: 525-535.artikel in tijdschrift
  • Hauer A.D., Uyttenhove C., Vos P. de, Stroobant V., Renauld J.C., Berkel T.J.C. van, Snick J. van & Kuiper J. (2005), Blockade of interleukin-12 function by protein vaccination attenuates atherosclerosis, Circulation 112: 1054-1062.artikel in tijdschrift
  • Dekker R.J., Thienen J.V. van, Rohlena J., Jager S.C.A. de, Elderkamp Y.W., Seppen J., Vries C.J. de, Biessen E.A.L., Berkel T.J.C. van, Pannekoek H. & Horrevoets A.J.G. (2005), Endothelial KLF2 links local arterial shear stress levels to the expression of vascular tone-regulating genes, American Journal of Pathology 67: 609-618.artikel in tijdschrift
  • Guo J., Eck M. van, Waard V. de, Maeda N., Benson G.N., Groot P.H. & Berkel T.J.C. van (2005), The presence of leukocyte CC-chemokine receptor 2 in CCR2 knockout mice promotes atherogenesis, Biochimica et Biophysica Acta 1740: 543-459.artikel in tijdschrift
  • Tietge U.J., Pratico D., Ding T., Funk C.D., Hildebrand RB, Berkel T.J.C. van & Eck M. van (2005), Macrophage-specific expression of group IIA sPLA2 results in accelerated atherogenesis by increasing oxidative stress, Journal of Lipid Research 46: 1604-1614.artikel in tijdschrift
  • Eck M. van, Pennings M., Hoekstra M., Out R. & Berkel T.J.C. van (2005), Scavenger receptor BI and ATP-binding cassette transporter A1 in reverse cholesterol transport and atherosclerosis, Current Opinion in Lipidology 16: 307-315.artikel in tijdschrift
  • Donners M.M., Bot I., Windt L.J. de, Berkel T.J.C. van, Daemen M.J., Biessen E.A.L. & Heeneman S. (2005), Low-dose FK506 blocks collar-induced atherosclerotic plaque development and stabilizes plaques in ApoE-/- mice, American Journal of Transplantation 5: 1204-1215.artikel in tijdschrift
  • Bot I., Guo J., Eck M. van, Santbrink P.J. van, Groot P.H., Hildebrand RB, Seppen J., Berkel T.J.C. van & Biessen E.A.L. (2005), Lentiviral shRNA silencing of murine bone marrow cell CCR2 leads to persistent knockdown of CCR2 function in vivo, Blood 106: 1147-1153.artikel in tijdschrift
  • Out R., Hoekstra M., Jager S.C.A. de, Vos P. de, Westhuyzen D.R. van der, Webb N.R., Eck M. van, Biessen E.A.L. & Berkel T.J.C. van (2005), Adenovirus-mediated hepatic overexpression of scavenger receptor class B type I accelerates chylomicron metabolism in C57BL/6J mice, Journal of Lipid Research 46: 1172-1181.artikel in tijdschrift
  • Hoekstra M., Out R., Kruijt J.K., Eck M. van & Berkel T.J.C. van (2005), Diet induced regulation of genes involved in cholesterol metabolism in rat liver parenchymal and Kupffer cells, Journal of Hepatology 42: 400-407.artikel in tijdschrift
  • Appeldoorn C.G., Bonnefoy A., Lutters B.C.H., Daenens K., Berkel T.J.C. van, Hoylaerts M.F. & Biessen E.A.L. (2005), Gallic acid antagonizes P-selectin-mediated platelet-leukocyte interactions: implications for the French paradox, Circulation 111: 106-112.artikel in tijdschrift
  • Willekens F.L., Werre J.M., Kruijt J.K., Roerdinkholder-Stoelwinder B., Groenen-Dopp Y.A., Bos A.G. van den, Bosman G.L. & Berkel T.J.C. van (2005), Liver Kupffer cells rapidly remove red blood cell-derived vesicles from the circulation by scavenger receptors, Blood 105: 2141-2145.artikel in tijdschrift
  • Guo J., Waard V. de, Eck M. van, Hildebrand RB, Wanrooij E.J.A. van, Kuiper J., Maeda N., Benson M.H., Groot P.H.E. & Berkel T.J.C. van (2005), Repopulation of apolipoprotein E knockout mice with CCR2-deficient progenitor cells does not inhibit ongoing atherosclerotic lesion development, Arteriosclerosis, Thrombosis and Vascular Biology 25: 1014-1019.artikel in tijdschrift
  • Rensen P.C.N., Berbee J.F.P., Schippers E.F., Dissel J.T. van, Bakker-Woudenberg A.J.M., Leeuwen H.J. van, Haas C.J.C., Kessel K.P.M., Berkel T.J.C. van, Kuiper J., Kooistra T & Havekes L.M. (2004), Apolipoproteins modulate inflammatory responses in rodents and humans: implications for sepsis., Shock 21: 153.artikel in tijdschrift (refereed)
  • Rossenberg S.M.W. van, Keulen A.C.I. van, Drijfhout J.W., Vasto S, Koerten H.K., Spies F., Noordende J.M. van t, Berkel T.J.C. van & Biessen E.A. (2004), Stable polyplexes based on arginine-containing oligopeptides for in vivo gene delivery, Gene Therapy 11: 457-464.artikel in tijdschrift
  • Nooijer R. de, Thüsen J.H. von der, Verkleij C.J.N., Kuiper J., Jukema J.W., Wall E.E. van der, Berkel T.J.C. van & Biessen E.A.L. (2004), Overexpression of IL-18 decreases intimal collagen content and promotes a vulnerable plaque phenotype in apolipoprotein-E-deficient mice, Arteriosclerosis, Thrombosis and Vascular Biology 24: 2313-9.artikel in tijdschrift (refereed)
  • Thüsen J.H. von der, Fekkes M.L., Passier R., Zonneveld A.J. van, Manfroid V., Berkel T.J.C. van & Biessen E.A.L. (2004), Adenoviral transfer of endothelial nitric oxide synthase attenuates lesion formation in a novel murine model of postangioplasty restenosis, Arteriosclerosis, Thrombosis and Vascular Biology 24: 357-362.artikel in tijdschrift (refereed)
  • Nooijer R. de, Thüsen J.H. von der, Verkleij C.J., Kuiper J., Jukema J.W., Wall E.E. van der, Berkel T.J.C. van & Biessen E.A.L. (2004), Overexpression of IL-18 decreases intimal collagen content and promotes a vulnerable plaque phenotype in apolipoprotein-E-deficient mice, Arteriosclerosis, Thrombosis and Vascular Biology 24: 2313-2319.artikel in tijdschrift (refereed)
  • Korporaal S.J.A., Relou I.A., Eck M. van, Strasser V., Bezemer M., Gorter G., Berkel T.J.C. van, Nimpf J., Akkerman J.W. & Lenting P.J. (2004), Binding of Low Density Lipoprotein to Platelet Apolipoprotein E Receptor 2' results in phosphorylation of p38MAPK, Journal of Biological Chemistry 279(50): 52526-52534.artikel in tijdschrift (refereed)
  • Lutters B.C.H., Leeuwenburgh M.A., Appeldoorn C.C.M., Molenaar T.J.M., Berkel T.J.C. van & Biessen E.A.L. (2004), Blocking endothelial adhesion molecules: a potential therapeutic strategy to combat atherogenesis, Current Opinion in Lipidology 15: 545-552.artikel in tijdschrift (refereed)
  • Out R., Hoekstra M., Spijkers J.A., Kruijt J.K., Eck M. van, Bos I.S.T., Twisk J & Berkel T.J.C. van (2004), Scavenger receptor class B type I is solely reponsible for the selective uptake of cholesteryl esters from HDL by the liver and the adrenals in mice, Journal of Lipid Research 45: 2088-2095.artikel in tijdschrift (refereed)
  • Out R., Kruijt J.K., Rensen P.C.N., Hildebrand R.B., Vos P. de, Eck M. van & Berkel T.J.C. van (2004), Scavenger receptor BI plays a role in facilitating chylomicron metabolism, Journal of Biological Chemistry 279(18): 18401-18406.artikel in tijdschrift (refereed)
  • Rensen P.C.N., Leeuwen S.H., Sliedregt L.A.J.M., Berkel T.J.C. van & Biessen E.A.L. (2004), Design and synthesis of novel N-acetylgalactosamine-terminated glycolipids for targeting of lipoproteins to the hepatic asialoglycoprotein receptor, Journal of Medicinal Chemistry 4: 5798-5808.artikel in tijdschrift (refereed)
  • Eck M. van, Bos I.S., Hildebrand R.B., Rij B.T. & Berkel T.J.C. van (2004), Dual role for scavenger receptor class B, type I on bone marrow-derived cells in atherosclerotic lesion development, AM J Pathol 165: 785-794.artikel in tijdschrift (refereed)
  • Rossenberg S.M.W. van, Keulen A.C.I. van, Drijfhout J.W., Vasto S., Koerten H.K., Spies F., Noordende J.M. van t, Berkel T.J.C. van & Biessen E.A.L. (2004), Stable polyplexes based on arginine-containing oligopeptides for in vivo gene delivery, Gene Therapy 11: 457-464.artikel in tijdschrift (refereed)
  • Thüsen J.H. von der, Fekkes M.L., Passier R., Zonneveld A.J. van, Mainfroid V., Berkel T.J.C. van & Biessen E.A.L. (2004), Adenoviral transfer of endothelial nitrocoxide synthase attenuates lesion formation in a novel murine model of postangioplasty restenosis, Arteriosclerosis, Thrombosis and Vascular Biology 24: 357-362.artikel in tijdschrift (refereed)
  • Willekens F.L., Werre J.M., Kruijt J.K., Roerdinkholder-Stoelwinder B., Groenen-Dopp Y.A., Bos A.G. van den, Bosman G.J. & Berkel T.J.C. van (2004), Liver Kupffer cells rapidly remove red blood cell-derived vesicles from the circulation by scavenger receptors, Blood 18: 2141-2145.artikel in tijdschrift (refereed)
  • Rossenberg S.M.W. van, Sliedregt-Bol K.M., Prince P.C., Berkel T.J.C. van, Boom J.H. van, Marel G.A. van der & Biessen E.A.L. (2003), A targeted peptide nucleic acid to down-regulate mouse microsomal triglyceride transfer protein expression in hepatocytes, Bioconjugate Chemistry 14: 1077-1082.artikel in tijdschrift (refereed)
  • Rossenberg S.M.W. van, Sliedregt-Bol K.M., Koning G., Elst H. van den, Berkel T.J.C. van, Boom J.H. van, Marel G.A. van der & Biessen E.A.L. (2003), Improvement of hepatocyte-specific gene expression by a targeted colchicine prodrug, ChemBioChem 4: 633-639.artikel in tijdschrift (refereed)
  • Hoen P.A.C. t, Out R., Commandeur J.N.M., Vermeulen N.P.E., Batenburg F.H.D. van, Manoharan M., Berkel T.J.C. van, Biessen E.A.L. & Bijsterbosch M.K. (2003), Selection of antisense oligodeoxynucleotides against Glutathione S-transferease Mu, RNA 8: 1572-1583.artikel in tijdschrift (refereed)
  • Appeldoorn C.C.M., Molenaar T.J.M., Bonnefoy A., Leeuwen S.H., Vandervoort P.A., Hoylaerts M.F., Berkel T.J.C. van & Biessen E.A.L. (2003), Rational optimization of a short human P-selectin-binding peptide leads to nanomolar affinity antagonists, Journal of Biological Chemistry 278(12): 10201-10207.artikel in tijdschrift (refereed)
  • Bot I., Thüsen J.H. von der, Donners M.M., Lucas A., Fekkes M.L., Jager S.C.A. de, Kuiper J., Daemen M.J., Berkel T.J.C. van, Heeneman S. & Biessen E.A.L. (2003), Serine protease inhibitor Serp-1 strongly impairs atherosclerotic lesion formation and induces a stable plaque phenotype in ApoE-/-mice, Circulation Research 93: 464-471.artikel in tijdschrift (refereed)
  • Guo J., Eck M. van, Twisk J, Maeda N., Benson G.N., Groot P.H. & Berkel T.J.C. van (2003), Transplantation of monocyte CC-chemokine receptor 2-deficient bone marrow into ApoE3-Leiden mice inhibits atherogenesis, Arterioscler.Thromb.Vasc.Biol. 23: 447-453.artikel in tijdschrift (refereed)
  • Hoekstra M., Kruijt J.K., Eck M. van & Berkel T.J.C. van (2003), Specific gene expression of ATP-binding cassette transporters and nuclear hormone receptors in rat liver parenchymal, endothelial, and Kupffer cells, Journal of Biological Chemistry 278(28): 25448-25453.artikel in tijdschrift (refereed)
  • Hoen P.A.C. t, Lans C. van der, Eck M. van, Bijsterbosch M.K., Berkel T.J.C. van & Twisk J (2003), Aorta of ApoE-deficient mice responds to atherogenic stimuli by a prelesional increase and subsequent decrease in the expression of antioxidant enzymes, Circulation Research 93: 262-269.artikel in tijdschrift (refereed)
  • Molenaar T.J.M., Twisk J, Haas S.A. de, Peterse N., Vogelaar B.J., Leeuwen S.H., Michon I.N., Berkel T.J.C. van, Kuiper J. & Biessen E.A.L. (2003), P-selectin as a candidate target in athero-sclerosis, Biochemical Pharmacology 66: 859-866.artikel in tijdschrift (refereed)
  • Amersfoort E.S. van, Berkel T.J.C. van & Kuiper J. (2003), Receptors, mediators, and mechanisms involved in bacterial sepsis and septic shock, Clinical Microbiology Reviews 16: 379-414.artikel in tijdschrift (refereed)
  • Eck M. van, Twisk J., Hoekstra M., Rij B.T., Lans C. van der, Bos I.S., Kruijt J.K., Kuipers F. & Berkel T.J.C. van (2003), Differential effects of scavenger receptor BI deficiency on lipid metabolism in cells of the arterial wall and in the liver, Journal of Biological Chemistry 278(26): 23699-23705.artikel in tijdschrift (refereed)
  • Thüsen J.H. von der, Kuiper J., Berkel T.J.C. van & Biessen E.A.L. (2003), Interleukins in atherosclerosis: molecular pathways and therapeutic potential, Pharmacological Reviews 55: 133-166.artikel in tijdschrift (refereed)
  • Thüsen J.H. von der, Vlijmen B.J.M. van, Hoeben R.C., Kockx M.M., Havekes L.M., Berkel T.J.C. van & Biessen E.A.L. (2002), Induction of atherosclerotic plaque rupture in apolipoprotein E - / - mice after adenovirus-mediated transfer of p53, Circulation: 2064-2070.artikel in tijdschrift (refereed)
  • Thüsen J.H. von der, Vlijmen B.J.M. van, Hoeben R.C., Kockx M., Havekes A.M., Berkel T.J.C. van & Biessen E.A. (2002), Induction of atherosclerotic plaque rupture in apolipoprotein E -/- mice after adenovirus-mediated transfer of p53, Circulation 105(17): 2064-2070.artikel in tijdschrift (refereed)
  • Biessen E.A.L., Sliedregt-Bol K.M., Hoen P.A.C. t, Prince P., Bilt E. van de, Valentijn A.R.P.M., Meeuwenoord N.J., Princen H., Bijsterbosch M.K., Marel G.A. van der, Boom J.H. van & Berkel T.J.C. van (2002), Design of a targeted peptide nucleic acid prodrug to inhibit hepatic human microsal triglyceride transfer protein expression in hepatocytes, Bioconjugate Chemistry 13: 295-302.artikel in tijdschrift (refereed)
  • Thüsen J.H. von der, Berkel T.J.C. van, Biessen E.A.L., Hoeben R.C., Vlijmen B.J.M. van, Havekes L.M. & Kockx M.M. (2002), Unraveling the mechanisms of plaque rupture in murine models, Circulation 106: 186.artikel in tijdschrift (refereed)
  • Rossenberg S.M.W. van, Sliedregt-Bol K.M., Meeuwenoord N.J., Berkel T.J.C. van, Boom J.H. van, Marel G.A. van der & Biessen E.A.L. (2002), Targeted lysosome disruptive elements for improvement of parenchymal liver cell-specific gene delivery, Journal of Biological Chemistry 277(48): 45803-45810.artikel in tijdschrift (refereed)
  • Biessen E.A.L., Sliedregt-Bol K.M., Hoen P.A.C. t, Prince P., Bilt E. van de, Valentijn A.R.P.M., Meeuwenoord N.J., Princen H., Bijsterbosch M.K., Marel M.A. van der, Boom J.H. van & Berkel T.J.C. van (2002), Design of a targeted peptide nucleic acid prodrug to inhibit hepatic human microsomal triglyceride transfer protein expression in hepatocytes., Bioconjugate Chemistry 13: 295-300.artikel in tijdschrift (refereed)
  • Hoen P.A.C. t, Out R., Commandeur J.N.M., Vermeulen N.P.E., Batenburg F.H.D. van, Manoharan M., Berkel T.J.C. van, Biessen E.A.L. & Bijsterbosch M.K. (2002), Selection of antisense oligodeoxynucleotides against glutathions S-transerase Mu, RNA 8: 1572-1583.artikel in tijdschrift (refereed)
  • Hoen P.A.C. t, Rosema B.-S., Commandeur J.N.M., Vermeulen N.P.E., Manoharan M., Berkel T.J.C. van, Biessen E.A.L. & Bijsterbosch M.K. (2002), Selection of effective antisense oligodeoxynucleotides with a green fluorescent protein-based assay. Discovery of selective and potent inhibitors of GST-Mu expression, European Journal of Biochemistry 269: 2574-2583.artikel in tijdschrift (refereed)
  • Hoen P.A.C. t, Rooseboom M., Bijsterbosch M.K., Berkel T.J.C. van, Vermeulen N.P.E. & Commandeur J.N.M. (2002), Induction of glutathione-S-transferase mRNA levels by chemopreventive selenocysteine Se-conjugates, Biochemical Pharmacology 63: 1843-1849.artikel in tijdschrift (refereed)
  • Appeldoorn C.C.M., Molenaar T.J.M., Leeuwen SH van, Berkel T.J.C. van & Biessen E.A.L. (2002), Rational optimization of P-selectin binding peptide leads to nanomolar affinity for the use in anti-atherothrombotic therapy, Circulation 106: II-84.artikel in tijdschrift (refereed)
  • Bijsterbosch M.K., Manoharan M., Dorland R., Veghel R. van, Biessen E.A.L. & Berkel T.J.C. van (2002), Bis-Cholesteryl-conjugated phosphorothioate oligodeoxynucleotides are highly selectively taken up by the liver, Journal of Pharmacy and Pharmacology 302: 619-626.artikel in tijdschrift (refereed)
  • Bot I., Thüsen J.H. von der, Donners M.M., Lucas A.R., Berkel T.J.C. van, Kuiper J., Heeneman S. & Biessen E.A.L. (2002), The serine protease inhibitor Serp-1 strongly impairs de novo atherosclerotic lesion formation in ApoE -/- mice, Circulation 106: II-300.artikel in tijdschrift (refereed)
  • Eck M. van, Bos I.S., Kaminski W.E., Orso E., Rothe G., Twisk J, Bottcher A., Amersfoort E.S. van, Christiansen-Weber T.A., Fung-Leung W.P., Berkel T.J.C. van & Schmitz G. (2002), Leukocyte ABCA1 controls susceptibility to atherosclerosis and macrophage recruitment into tissues, Proceedings National Academy of Sciences 99: 6298-6303.artikel in tijdschrift (refereed)
  • Eck M. van, Bos S. & Berkel T.J.C. van (2002), Macrophage scavenger receptor B1 (SRBI) deficiency promotes atherosclerotic lesion development, Circulation 106: II-77.artikel in tijdschrift (refereed)
  • Eck M. van, Twisk J, Rij B. van, Lans C. van der, Hoekstra M., Bos S., Kuipers F. & Berkel T.J.C. van (2002), Differential effects of scavenger receptor BI (SRBI) deficiency on the arterial wall and the liver, Circulation 106: II-77.artikel in tijdschrift (refereed)
  • Hoen P.A.C. t, Out R., Commandeur J.N.M., Vermeulen N.P.E., Batenburg F.H.D. van, Manoharan M., Berkel T.J.C. van, Biessen E.A.L. & Bijsterbosch M.K. (2002), Selection of antisense oligodeoxynucleotides against glutathione S-transferase Mu, RNA 8: 1572-1583.artikel in tijdschrift (refereed)
  • Hoen P.A.C. t, Rosema S.W., Commandeur J.N.M., Vermeulen J.J., Manoharan M., Berkel T.J.C. van & Biessen E.A.L. (2002), Selection of effective antisense oligodeoxynucleotides with a green fluorescent protein-based assay. Discovery of selective and potent inhibitors of glutathione S-transferase Mu expression, European Journal of Biochemistry 269: 2574-2583.artikel in tijdschrift (refereed)
  • Michon I.N., Hauer A.D., Thüsen J.H. von der, Molenaar T.J.M., Berkel T.J.C. van & Kuiper J. (2002), Targeting of peptides to restenotic vascular smooth muscle cells using phage display in vitro and in vivo, Biochimica et Biophysica Acta 1591: 87-97.artikel in tijdschrift (refereed)
  • Michon I.N., Penning L.C., Molenaar T.J.M., Berkel T.J.C. van & Kuiper J. (2002), The effect of TGF-beta receptor binding peptides on smooth muscle cells, Biochemical and Biophysical Research Communications 293: 1279-1286.artikel in tijdschrift (refereed)
  • Molenaar T.J.M., Appeldoorn C.C.M., Haas S.A. de, Michon I.N., Bonnefoy A., Hoylarts M.F., Pannekoek H., Berkel T.J.C. van, Kuiper J. & Biessen E.A.L. (2002), Specific inhibition of P-selectin-mediated cell adhesion by phage display-derived peptide antagonists, Blood 100: 3570-3577.artikel in tijdschrift (refereed)
  • Molenaar T.J.M., Michon I.N., Haas S.A. de, Berkel T.J.C. van & Biessen E.A.L. (2002), Uptake and processing of modified bacteriophage M13 in mice: implications for phage display, Virology 293: 182-191.artikel in tijdschrift (refereed)
  • Molenaar T.J.M., Korporaal S.J.A., Akkerman J.W., Berkel T.J.C. van, Kuiper J. & Biessen E.A.L. (2002), Peptide antagonists inhibit the interaction of P-selectin with sulfatide-containing liposomes and reduce platelet aggregation, Circulation 106: II-120.artikel in tijdschrift (refereed)
  • Molenaar T.J.M., Berkel T.J.C. van, Kuiper J., Mayadas-Norton T. & Biessen E.A.L. (2002), Specific binding and cleavage of P-selectin by μ-calpain is mediated by a highly conserved pentapeptide motif, Circulation 106: II-150.artikel in tijdschrift (refereed)
  • Rijken D.C., Kaaden M.E. van der, Groeneveld E., Barrett-Bergshoeff M.M., Berkel T.J.C. van & Kuiper J. (2002), Characterization of the binding of urokinase-type plasminogen activator to the asialoglycoprotein receptor, Thrombosis and Haemostasis 88: 83-88.artikel in tijdschrift (refereed)
  • Thüsen J.H. von der, Berkel T.J.C. van, Biessen E.A.L., Hoeben R.C., Vlijmen B.J.M. van, Havekes L.M. & Kocks M.M. (2002), Unraveling the mechanism of plaque rupture in marine models. Response, Circulation 106: 186-187.artikel in tijdschrift (refereed)
  • Thüsen J.H. von der, Nooijer R. de, Wanrooij E.J.A. van, Berkel T.J.C. van, Lai M.C. & Biessen E.A.L. (2002), Cathepsin S expression level is critical in atherosclerotic lesion homeostasis, Circulation 106: II-43.artikel in tijdschrift (refereed)
  • Eck-Smaling M.M. van, Willems Van Dijk J.A.P., Herijgers N., Hofker M.H., Groot PH & Berkel T.J.C. van (2001), Essential role for the (hepatic) LDL receptor in macrophage apolipoprotein E-induced reduction in serum cholesterol levels and atherosclerosis., Atherosclerosis 154: 103-112.artikel in tijdschrift (refereed)
  • Sliedregt L.A.J.M., Rossenberg S.M.W. van, Autar R., Valentijn A.R.P.M., Marel G.A. van der, Boom J.H. van, Piperi C., Merwe P.A. van der, Kuiper J., Berkel T.J.C. van & Biessen E.A.L. (2001), Design and synthesis of a multivalent homing device for targeting to murine CD22, Bioorganic and Medicinal Chemistry 9(1): 85-97.artikel in tijdschrift (refereed)
  • Jong M.C., Rensen P.C.N., Dahlmans V.E.H., Boom H van der, Berkel T.J.C. van & Havekes A.M. (2001), Apolipoprotein C-III deficiency accerates triglyceride hydrolysis by lipoprotein lipase in wild-type and ApoE knockout mice, Journal of Lipid Research 42(10): 1578-1585.artikel in tijdschrift (refereed)
  • Sliedregt L.A.J.M., Rossenberg S.M.W. van, Autar R., Valentijn A.R.P.M., Marel G.A. van der, Boom J.H. van, Piperi C., Merwe P.A. van der, Kuiper J., Berkel T.J.C. van & Biessen E.A. (2001), Design and synthesis of multivalent homing device for targeting to murine CD22., Bioorganic and Medicinal Chemistry 9(1): 85-97.artikel in tijdschrift (refereed)
  • Jong M.C., Rensen P.C.N., Dahlmans V.E.H., Boom H van der, Berkel T.J.C. van & Havekes L.M. (2001), Apolipoprotein C-III deficiency accelerates triglyceride hydrolysis by lipoprotein lipase in wild-type and apoE knockout mice, Journal of Lipid Research 42: 1578-1585.artikel in tijdschrift (refereed)
  • Vlijmen B.J.M. van, Gerritsen G, Franken AL, Boesten L.S.M., Kockx M.M., Gijbels M.J.J., Vierboom M.P.M., Eck M. van, Water B. van de, Berkel T.J.C. van & Havekes L.M. (2001), Macrophage p53 deficiency leads to enhanced atherosclerosis in ApoE*3-Leiden transgenic mice, Circulation Research 88: 780-786.artikel in tijdschrift (refereed)
  • Eck-Smaling M.M. van, Winther M.P.J. de, Herijgers N., Havekes L.M., Hofker M.H., Groot PH & Berkel T.J.C. van (2000), Effect of human scavenger receptor class A overexpression in bone marrow-derived cells on cholesterol levels and atherosclerosis in ApoE-deficient mice., Arteriosclerosis, Thrombosis and Vascular Biology 20: 2600-2606.artikel in tijdschrift (refereed)
  • Tacken P.J., Teusink B, Jong M.C., Harats D, Havekes L.M., Hofker M.H., Koffeman L.J. & Berkel T.J.C. van (2000), LDL receptor deficiency unmasks altered VLDL triglyceride metabolism in VLDL receptor transgenic and knockout mice., Journal of Lipid Research 41: 2055-2062.artikel in tijdschrift (refereed)
  • Herijgers N., Winther M.P.J. de, Eck M. van, Havekes A.M., Hofker M.H., Koffeman L.J. & Berkel T.J.C. van (2000), Effect of human scavenger receptor class A oerexpression in bone marrow-derived cells on lipoprotein metabolism and atherosclerosis in low density lipoprotein receptor knockout mice, Journal of Lipid Research 41(9): 1402-1409.artikel in tijdschrift (refereed)
  • Herijgers N., Winther M.P.J. de, Eck-Smaling M.M. van, Havekes L.M., Hofker M.H., Hoogerbrugge P.M. & Berkel T.J.C. van (2000), Effect of human scavenger receptor class A overexpression in bone marrow-derived cells on lipoprotein metabolism and atherosclerosis in low density lipoprotein receptor knockout mice., Journal of Lipid Research 41: 1402-1409.artikel in tijdschrift (refereed)
  • Eck-Smaling M.M. van, Herijgers N., Willems Van Dijk J.A.P., Havekes L.M., Hofker M.H., Groot PH & Berkel T.J.C. van (2000), Effect of macrophage-derived mouse ApoE, human ApoE3-Leiden, and human ApoE2 (Arg158-->Cys) on cholesterol levels and atherosclerosis in ApoE-deficient mice., Arteriosclerosis, Thrombosis and Vascular Biology 20: 119-127.artikel in tijdschrift (refereed)
  • Rensen P.C.N., Jong M.C., Vark LC, Boom H van der, Hendriks W.L., Berkel T.J.C. van, Biessen E.A.L. & Havekes A.M. (2000), Apolipoprotein E is resistant to intracellular degradation in vitro and in vivo. Evidence for retroendocytosis, Journal of Biological Chemistry 275(12): 8564-8571.artikel in tijdschrift (refereed)
  • Eck M. van, Winther M.P.J. de, Herijgers N., Havekes A.M., Hofker M.H., Groot PH & Berkel T.J.C. van (2000), Effect of human scavenger receptor class A overexpression in bone marrow-derived cells on cholesterol levels and atherosclerosis in apoE-deficient mice, Arteriosclerosis, Thrombosis and Vascular Biology 20: 2600-2606.artikel in tijdschrift (refereed)
  • Eck M. van, Herijgers N., Dijk K.W. van, Havekes A.M., Hofker M.H., Groot PH & Berkel T.J.C. van (2000), Effect of macrophage-derived mouse ApoE, human ApoE3, human ApoE2 (Arg155-Cys) on cholesterol levels and atherosclerosis in ApoE-deficient mice, Arteriosclerosis, Thrombosis and Vascular Biology 20(1): 119-127.artikel in tijdschrift (refereed)
  • Biessen E.A.L., Valentijn A.R.P.M., De Vrueh R.L., Bilt E. van de, Sliedregt L.A.J.M., Prince P.C., Bijsterbosch M.K., Boom J.H. van, Marel G.A. van der, Mulder F.E. & Berkel T.J.C. van (2000), Novel hepatotrophic prodrugs of the antiviral nucleoside 9-(2-phosphonylmethoxyethyl)adenine with improved pharmacokinetics and antiviral activity., The FASEB Journal 14: 1784-1792.artikel in tijdschrift (refereed)
  • Bijsterbosch M.K., Boom J.H. van, Marel G.A. van der, Mulder F.E. & Berkel T.J.C. van (2000), Novel hepatotrophic prodrugs of the antiviral nucleoside 9-(2-phosphonylmethoxyethyl) adenine with improved pharmokinetics and antiviral activity, The FASEB Journal 14: 1784-1792.artikel in tijdschrift (refereed)
  • Vlijmen B.J.M. van, Willems van Dijk K., Hof B.H. van 't, Zee A. van der, Santamarina-Fojo S., Berkel T.J.C. van, Havekes L.M. & Hofker M.H. (1999), In LDL receptor-deficient mice, catabolism of remnant lipoproteins requires a high level of apoE but is inhibited by excess apoE, Journal of Lipid Research 40: 336-344.artikel in tijdschrift (refereed)
  • Fluiter K., Sattler W., Beer M.C. de, Connel P.M., Westhuijzen D.R. van der & Berkel T.J.C. van (1999), Scavenger receptor BI mediates the selective uptake of oxidized cholesterolesters by rat liver, Journal of Biological Chemistry 26(13): 8893-8899.artikel in tijdschrift (refereed)
  • Sliedregt L.A.J.M., Rensen P.C.N., Rump E.T., Santbrink P.J. van, Bijsterbosch M.K., Valentijn A.R.P.M., Marel G.A. van der, Boom J.H. van, Berkel T.J.C. van & Biessen E.A.L. (1999), Design and synthesis of novel amphiphilic dendritic galactosides for selective targeting of liposomes to the hepatic asialoglycoprotein receptor, Journal of Medicinal Chemistry 42: 609-618.artikel in tijdschrift (refereed)
  • Versluis J., Rump E.T., Rensen P.C.N., Berkel T.J.C. van & Bijsterbosch M.K. (1999), The stable incorporation of a lipophilic daunorubicin prodrug into apolipoprotein E-exposing liposomes induces uptake of the prodrug via the LDL receptor in vivo, Journal of Pharmacology and Experimental Therapeutics 289: 1-7.artikel in tijdschrift (refereed)
  • Vries H.E., Buchner B., Berkel T.J.C. van & Kuiper J. (1999), Specific interaction of oxidized low density lipoprotein with macrophage-derived foam cells isolated from rabbit atherosclerotic lesions, Arteriosclerosis, Thrombosis and Vascular Biology 19: 638-645.artikel in tijdschrift (refereed)
  • Vries H.E., Moor A.C.E., Dubbelman T.M.A.R., Berkel T.J.C. van & Kuiper J. (1999), Oxidized low-density lipoprotein as a delivery system for photosensitizers: implications for photodynamic therapy of atherosclerosis, Journal of Pharmacology and Experimental Therapeutics 289: 528-534.artikel in tijdschrift (refereed)
  • Vries H.E., Moor A.C.E., Dubbelman T.M.A.R., Berkel T.J.C. van & Kuiper J. (1999), Oxidized low-density lipoprotein as a delivery system for photosensitizers: implications for photodynamic therapy of atherosclerosis, Journal of Pharmacology and Experimental Therapeutics 289: 528-534.artikel in tijdschrift (refereed)
  • Willems Van Dijk J.A.P., Vlijmen B.J.M. van, Hof H.B. van 't, Zee A. van der, Santamarina-Fojo S., Berkel T.J.C. van, Havekes L.M. & Hofker M.H. (1999), In LDL receptor-deficient mice, catabolism of remnant lipoproteins requires a high level of apoE but is inhibited by excess apoE., Journal of Lipid Research 40: 336-344.artikel in tijdschrift (refereed)
  • Willems van Dijk K., Vlijmen B.J.M. van, Hof H.B. van 't, Zee A van der, Santamarina-Fojo S., Berkel T.J.C. van, Havekes A.M. & Hofker M.H. (1999), In LDL receptor-deficient mice, catabolism of remnant lipoproteins requires a high level of apoE but is inhibited by excess apoE., Journal of Lipid Research 40: 336-344.artikel in tijdschrift (refereed)
  • Vlijmen B.J.M. van, Rohlmann A., Page S.T., Bensadoun A, . Bos I.S.T., Berkel T.J.C. van, Havekes A.M. & Hertz J. (1999), An extrahepatic receptor-associated protein-sensitive mechanism is involved in the metabolism of triglyceride-rich lipoprotein., Journal of Biological Chemistry 274: 35219-35226.artikel in tijdschrift (refereed)
  • Biessen E.A.L., Bilt E. van de, Prince P., Valentijn A.R.P.M., Marel G.A. van der, Boom J.H. van & Berkel T.J.C. van (1999), Tissue specific down-regulation of microsomal triglyceride tranfer protein by glycoconjugated PNA, Circulation 100: 4305-4310.artikel in tijdschrift (refereed)
  • Berkel T.J.C. van, Velzen A.G. van, Kruijt J.K., Suzuki H. & Kodama T. (1998), Oxidized LDL catabolism in scavenger receptor class A type I, II, knock out mice, Circulation 98: I-108.artikel in tijdschrift (refereed)
  • Berkel T.J.C. van, Velzen A.G. van, Kruijt J.K., Suzuki H. & Kodama T. (1998), Uptake and catabolism of modified LDL in scavenger-receptor class A type I/II knock-out mice, Biochemical Journal 331: 29-35.artikel in tijdschrift (refereed)
  • Biessen E.A.L., Vietsch H., Kuiper J. & Berkel T.J.C. van (1998), Liver uptake of phosphodiester oligodeoxynucleotides is mediated by scavenger receptor type binding sites, Molecular Pharmacology 53: 262-269.artikel in tijdschrift (refereed)
  • Bijsterbosch M.K., Smeijsters L.J.J.W. & Berkel T.J.C. van (1998), Disposition of the acyclic nucleoside phosphonate (s)-9-(3-hydroxy-2-phosphonylmethoxypropyl) adenine [(s)-HPMPA], Antimicrobial Agents and Chemotherapy 42: 1146-1150.artikel in tijdschrift (refereed)
  • Eck M. van, Zimmerman R., Zechner R., Groot P.H.E. & Berkel T.J.C. van (1998), Role of macrophage-derived LPL in lipoprotein metabolism, Circulation 98: I-663.artikel in tijdschrift (refereed)
  • Fluiter K., Sattler W., Westhuijzen D.R. van der & Berkel T.J.C. van (1998), Scavenger receptor BI mediates the selective uptake of oxidized cholesterol esters by rat liver, Circulation 98: I-202.artikel in tijdschrift (refereed)
  • Fluiter K., Westhuijzen D.R. van der & Berkel T.J.C. van (1998), In vivo regulation of scavenger receptor BI and the selective uptake of HDL cholesteryl(esters) in rat liver parenchymal and Kupffer cells, Journal of Biological Chemistry 273(14): 8434-8438.artikel in tijdschrift (refereed)
  • Herijgers N., Eck M. van, Korporaal S.J.A., Groot P.H.E., Hoogerbrugge P.M. & Berkel T.J.C. van (1998), Crucial role of the macrophage low density receptor (LDLr) in foam cell formation and the development of atherosclerosis, Circulation 98: I-385.artikel in tijdschrift (refereed)
  • Kuiper J., Vries H.E., Moor A.C.E., Dubbelman T.M.A.R. & Berkel T.J.C. van (1998), Arteriosclerosis and photodynamic therapy: oxidatively modified LDL as a delivery system for photosensitizer, Circulation 98: I-635.artikel in tijdschrift (refereed)
  • Kuipers F., Jong M.C., Lin Y., Eck M. van, Havinga R., Bloks V., Verkade H.J., Hofker M.H., Moshage H., Berkel T.J.C. van, Vonk R.J. & Havekes L.M. (1998), Impaired secretion of very low density lipoprotein triglycerides by apolipoprotein E-deficient mouse hepatocytes, Journal of Clinical Investigation 100: 2915-2922.artikel in tijdschrift (refereed)
  • Oosten M. van, Bilt E. van de, Berkel T.J.C. van & Kuiper J. (1998), New scavenger receptor-like receptors for the binding of lipopolysaccharide to liver endothelial and Kupffer cells, Infection and Immunity 66: 5107-5112.artikel in tijdschrift (refereed)
  • Rensen P.C.N., Oosten M. van, Amersfoort E.S. van, Eck M. van, Kuiper J. & Berkel T.J.C. van (1998), Apolipoprotein E is increased by bacterial LPS in vivo and protects against LPS-induced lethality, Circulation 98: I-305.artikel in tijdschrift (refereed)
  • Rensen P.C.N., Sliedregt L.A.J.M., Santbrink P.J. van, Berkel T.J.C. van & Biessen E.A.L. (1998), Novel glycolipids with high affinity for the hepatic asialoglycoprotein receptor are potent cholesterol-lowering agents, Circulation 98: I-451.artikel in tijdschrift (refereed)
  • Rump E.T., Vrueh R.L.A. de, Sliedregt L.A.J.M., Biessen E.A.L., Berkel T.J.C. van & Bijsterbosch M.K. (1998), Preparation of conjugates of oligodeoxynucleotides and lipid structures, and their interaction with low-density lipoprotein, Bioconjugate Chemistry 9: 341-349.artikel in tijdschrift (refereed)
  • Versluis J., Rensen P.C.N., Rump E.T., Berkel T.J.C. van & Bijsterbosch M.K. (1998), LDL receptor-mediated delivery of a lipophilic daunorubicin derivative to B16 tumours in mice using apolipoprotein E-enriched liposomes, British Journal of Cancer 78: 1607-1614.artikel in tijdschrift (refereed)
  • Versluis J., Rump E.T., Rensen P.C.N., Berkel T.J.C. van & Bijsterbosch M.K. (1998), Synthesis of a lipophilic daunorubicin derivative and its incorporation into lipidic carriers developed for LDL receptor-mediated tumor therapy, Pharmaceutical Research 15: 531-537.artikel in tijdschrift (refereed)
  • Vries H.E., Ronke E., Reinders J.H., Berkel T.J.C. van & Kuiper J. (1998), Acute effects of oxidized low density lipoprotein on the metabolic responses of macrophages, The FASEB Journal 12: 111-118.artikel in tijdschrift (refereed)
  • Vrueh R.L.A. de, Rump E.T., Biessen E.A.L., Berkel T.J.C. van & Bijsterbosch M.K. (1998), Cryopreservation of 9-(2-phosphonylmethoxyethyl)adenine (PMEA) loaded lactosylated reconstituted high-density lipoprotein, Journal of Pharmaceutical Sciences 1: S-100.artikel in tijdschrift (refereed)
  • Biessen E.A.L., Vietsch H., Rump E.T., Bijsterbosch M.K. & Berkel T.J.C. van (1998), Targeted delivery of antisense oligodeoxynucleotides to the hepatocyte in vivo, Methods in Enzymology.artikel in tijdschrift (refereed)
  • Biessen E.A.L. & Berkel T.J.C. van (1998), Receptor-dependent cell specific delivery of antisense oligonucleotides. In: Cardiovascular specific gene expression. Dordrecht, The Netherlands: Kluwer Academic Publishers.boekdeel
  • Berkel T.J.C. van (1998), The concerted action of various cell types from the liver in lipoprotein catabolism (Lezing). University of Graz, Austria.overig
  • Berkel T.J.C. van (1998), Receptor-dependent cellular targeting of synthetic gene delivery systems (Lezing). Keystone, Colorado, USA.overig
  • Berkel T.J.C. van (1998), Gene Therapy: A view from Academia (Lezing). London, UK.overig
  • Berkel T.J.C. van (1998), In vivo fate of antisense oligonucleotides (Lezing). Napels, Italy.overig
  • Berkel T.J.C. van (1998), Role of scavenger-receptors class A and B in (modified) LDL and HDL metabolism (Lezing). Geneva, Switzerland.overig
  • Berkel T.J.C. van (1998), Role of scavenger-receptors in lipoprotein metabolism (Lezing). Utrecht, The Netherlands.overig
  • Berkel T.J.C. van (1998), New delivery systems for the specific targeting of drugs (Lezing). Shizuoka, Japan.overig
  • Berkel T.J.C. van (1998), The importance of scavenger-receptor class A and B for the metabolism of modified LDL and HDL by sinusoidal liver cells (Lezing). Christchurch, New Zealand.overig
  • Berkel T.J.C. van (1998), Oxidized LDL catabolism in scavenger receptor class A type I, II knock out mice (Lezing). Dallas, USA.overig
  • Berkel T.J.C. van (1998), Receptor-dependent cellular targeting of synthetic gene-delivery systems (Lezing). Houston, USA.overig
  • Keulen A.C.I. van, Drijfhout J.W., Noordende J.M. van t, Spies F., Koerten H.K., Berkel T.J.C. van & Biessen E.A.L. (1998), Development of non-viral vectors for hepatic gene therapy in vivo (Lezing). Vividale del Friuli, Udine, Italy.overig
  • Rensen P.C.N., Keulen A.C.I. van, Herijgers N., Sliedregt L.A.J.M., Santbrink P.J. van, Berkel T.J.C. van & Biessen E.A.L. (1998), Recombinant chylomicrons as promosing carriers of DNA for non-viral gene therapy (Lezing). Cividale del Friuli, Udine, Italy.overig
  • Kuipers F., Jong M.C., Lin Y.G., Eck M. van, Havinga R., Bloks V., Verkade H.J., Hofker M.H., Moshage H. & Berkel T.J.C. van (1997), Impaired secretion of very low density lipoprotein-triglycerides by apolipoprotein e-deficient mouse hepatocytes., Journal of Clinical Investigation 100: 2915-2922.artikel in tijdschrift (refereed)
  • Kuipers F., Jong M.C., Lin Y.G., Eck M. van, Havinga R., Bloks V., Verkade H.J., Hofker M.H., Moshage H., Berkel T.J.C. van & Vonk R. (1997), Impaired secretion of very low density lipoprotein-triglycerides by apolipoprotein E-deifcient mouse hepatocytes., Journal of Clinical Investigation 100: 2915-2922.artikel in tijdschrift (refereed)
  • Kuipers F., Jong M. de, Lin Y.G., Eck M. van, Havinga R., Bloks V., Verkade H.J., Hofker M.H., Moshage H., Berkel T.J.C. van, Vonk R. & Havekes A.M. (1997), Impaired secretion of very low density lipoprotein-triglyceride by apoliprotein E-deficient mouse hepatocytes., Journal of Clinical Investigation 100: 2915-2922.artikel in tijdschrift (refereed)
  • Berkel T.J.C. van, Eck M. van, Herijgers N., Hoogerbrugge P.M. & Groot P.H.E. (1997), Modulation of arteriosclerosis by gene therapy.. In: Wall E., et al .. (Red.) Vascular Medicine. Amsterdam: Kluwer. 197-218.boekdeel
  • Herijgers N., Eck M. van, Yates J.R.W., Pearce N.J., Hoogerbrugge P.M., Groot P.H.E. & Berkel T.J.C. van (1997), Bone marrow transplantation in Apoliprotein E-deficient mice: effect of ApoE gene-dosage on cholesterol, triglycerines, remnant catabolism and atherosclerosis., Arteriosclerosis, Thrombosis and Vascular Biology 17: 1995-2003.artikel in tijdschrift (refereed)
  • Eck M. van, Herijgers N., Vidgeon-Hart M., Pearce N.J., Hoogerbrugge P.M., Groot P.H.E. & Berkel T.J.C. van (1997), Bone marrow transplantation in Apolipoprotein E-deficient mice: effect of ApoE gene-dosage on serum lipid concentrations, beta-VLDL catabolism and artherosclerosis., Arteriosclerosis, Thrombosis and Vascular Biology 17: 3117-3126.artikel in tijdschrift (refereed)
  • van de Water B, van Berkel TJ & Kuiper J (1994), Activation of rat Kupffer cells to tumoricidal cells by the immunomodulator muramyl tripeptide-phosphatidylethanolamine incorporated into the novel drug carrier lactosylated low density lipoprotein., Molecular Pharmacology 45(5): 971-7.artikel in tijdschrift (refereed)

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