Ludovic Bretin
Gast (onderzoeker)
- Naam
- Dr. L.R. Bretin
- Telefoon
- 071 5272727
- l.r.bretin@lic.leidenuniv.nl
- ORCID iD
- 0000-0002-2949-0512
Gast (onderzoeker)
- Faculteit der Wiskunde en Natuurwetenschappen
- LIC
- Chemistry for a sustainable society
- Metals in Catalysis, Biom & Inorganic Mat.
- Bretin L.R., Husiev Y., Vadde R., Zhang L., Hakkennes M.L.A., Abyar S., Johns A.C., Le Dévédec S.E., Betancourt T., Kornienko A. & Bonnet S.A. (2024), Red‐light activation of a microtubule polymerization inhibitor via amide functionalization of the ruthenium photocage, Angewandte Chemie (International Edition) 63(5): e202316425.
- Abyar S., Huang L., Husiev Y., Bretin L.R., Chau B., Vadde R., Wildeman J.H., Belfor K., Wijyay L.S., Noord V.E. van der, Harms A.C., Siegler M.A., Le Dévédec S.E. & Bonnet S.A. (2024), Oxygen-dependent interactions between the ruthenium cage and the photoreleased inhibitor in NAMPT-targeted photoactivated chemotherapy, Journal of Medicinal Chemistry 67(13): 11086–11102.
- Zhou X., Wang P., Vadde R., Zhang L., Jiang S., Li X., Abyar S., Papadopoulou P., Shao Y., Bretin L.R., Siegler M.A., Buda F., Kros A., Fan J., Peng X., Sun W. & Bonnet S.A. (2023), In vivo metallophilic self-assembly of a light-activated anticancer drug, Nature Chemistry 15: 980-987 (980-987).
- Zhang L., Wang P., Zhou X.Q., Bretin L.R., Zeng X., Husiev Y., Polanco Rivas E.A., Zhao G., Wijaya L.S., Biver T., Le Dévédec S.E., Sun W. & Bonnet S. (2023), Cyclic ruthenium-peptide conjugates as integrin-targeting phototherapeutic prodrugs for the treatment of brain tumors, Journal of the American Chemical Society 145(27): 14963-14980.
- Chen Q., Cuello-Garibo J.A., Bretin L.R., Zhang L., Ramu V., Aydar Y., Batsiun Y., Bronkhorst S., Husiev Y., Beztsinna N., Chen L., Zhou X.Q., Schmidt C., Ott I., Jager M.J., Brouwer A.M., Snaar-Jagalska B.E. & Bonnet S.A. (2022), Photosubstitution in a trisheteroleptic ruthenium complex inhibits conjunctival melanoma growth in a zebrafish orthotopic xenograft model, Chemical Science 13(23): 6899-6919.