Ludo Bretin
Onderzoeker
- Naam
- Dr. L.R. Bretin
- Telefoon
- +31 71 527 4261
- l.r.bretin@lic.leidenuniv.nl
- ORCID iD
- 0000-0002-2949-0512
Onderzoeker
- Wiskunde en Natuurwetenschappen
- Leiden Institute of Chemistry
- LIC/Energy & Sustainability
- LIC/ES/Metal in Cat. Biom. & Inorg. Mat.
- Bretin L.R., Husiev Y., Vadde R., Zhang L., Hakkennes M.L.A., Abyar S., Johns A.C., Le Dévédec S.E., Betancourt T., Kornienko A. & Bonnet S.A. (2024), Red‐light activation of a microtubule polymerization inhibitor via amide functionalization of the ruthenium photocage, Angewandte Chemie (International Edition) 63(5): e202316425.
- Zhang L., Wang P., Zhou X.Q., Bretin L.R., Zeng X., Husiev Y., Polanco Rivas E.A., Zhao G., Wijaya L.S., Biver T., Le Dévédec S.E., Sun W. & Bonnet S. (2023), Cyclic ruthenium-peptide conjugates as integrin-targeting phototherapeutic prodrugs for the treatment of brain tumors, Journal of the American Chemical Society 145(27): 14963-14980.
- Zhou X., Wang P., Vadde R., Zhang L., Jiang S., Li X., Abyar S., Papadopoulou P., Shao Y., Bretin L.R., Siegler M.A., Buda F., Kros A., Fan J., Peng X., Sun W. & Bonnet S.A. (2023), In vivo metallophilic self-assembly of a light-activated anticancer drug, Nature Chemistry 15: 980-987 (980-987).
- Chen Q., Cuello-Garibo J.A., Bretin L.R., Zhang L., Ramu V., Aydar Y., Batsiun Y., Bronkhorst S., Husiev Y., Beztsinna N., Chen L., Zhou X.Q., Schmidt C., Ott I., Jager M.J., Brouwer A.M., Snaar-Jagalska B.E. & Bonnet S.A. (2022), Photosubstitution in a trisheteroleptic ruthenium complex inhibits conjunctival melanoma growth in a zebrafish orthotopic xenograft model, Chemical Science 13(23): 6899-6919.