Universiteit Leiden

nl en

Kees Pleij

Hoogleraar / emeritus

Naam
Prof.dr. C.W.A. Pleij
Telefoon
+31 71 527 4769
E-mail
c.pley@chem.leidenuniv.nl

Hoogleraar / emeritus

  • Wiskunde en Natuurwetenschappen
  • Leiden Institute of Chemistry
  • LIC/Molecular Genetics

Werkadres

Gorlaeus Laboratoria
Einsteinweg 55
2333 CC Leiden
Kamernummer HB221

Contact

  • Olsthoorn R.C.L., Reumerman R., Hilbers C.W., Pleij C.W.A. & Heus H.A. (2010), Functional analysis of the SRV-1 RNA frameshifting pseudoknot, Nucleic Acids Research 38(21): 7665-7672.artikel in tijdschrift (refereed)
  • Chen S.C., Gultyaev A.P., Pleij C.W. & Olsthoorn R.C. (2009), A Secondary Structure Model for the 3'-Untranslated Region of Ilarvirus RNAs. In: Diversity, Properties and Parameters.. 65-83.boekdeel
  • Chen S.C., Born E. van den, Pleij C.W.A., Snijder E.J. & Olsthoorn R.C.L. (2007), A new structure model for the packaging signal in the genome of group IIa Coronaviruses., Journal of Virology 81(12): 6771-6774.artikel in tijdschrift
  • Olsthoorn-Tieleman L.N., Palstra R.J., Wezel G.P. van, Bibb M.J. & Pleij C.W.A. (2007), Elongation factor Tu3 from the kirromycin-producer Streptomyces ramocissimus is resistant to three classes of EF-Tu-specific inhibitors, Journal of Bacteriology 189: 3581-3590.artikel in tijdschrift (refereed)
  • Ongus J.R., Roode E.C., Pleij C.W.A., Vlak J.M. & Oers M.M. (2006), The 5' non-translated region of Varroa destructor virus 1 (genus Iflavirus): structure prediction and IRES activity in Lymantria dispar cells, Journal of General Virology 87: 3397-3407.artikel in tijdschrift (refereed)
  • Nagel J.H.A., Flamm C., Hofacker I.L., Franke K., Smit M.H. de, Schuster P. & Pleij C.W.A. (2006), Structural parameters affecting the kinetics of RNA hairpin formation, Nucleic Acids Research 34: 3568-3576.artikel in tijdschrift (refereed)
  • Gultyaev A.P., Pleij C.W.A. & Westhof E. (2005), RNA structure: Pseudoknots. In: "Encyclopedia of life sciences". In: Encyclopedia of life sciences. Chichester: John Wiley & Sons, Ltd.boekdeel
  • Koening R., Barends S., Gultyaev A.P., Lesemann D.-E., Vetten H.J., Loss S. & Pleij C.W.A. (2005), Nemesia ring necrosis virus: a new tymovirus with a genomic RNA having a histidylatable tobamovirus-like 3¿ end, Journal of General Virology 86: 1827-1833.artikel in tijdschrift
  • Koenig R., Pleij C.W.A., Leseman D.-E., Loss S. & Vetten H.J. (2005), Molecular characterization of isolates of anagyris vein yellowing virus, plantage mottle virus and scrophularia mottle virus ¿ comparison of various approaches for tymovirus classification, Arch. Virol. 150: 2325-2338.artikel in tijdschrift
  • Gultyaev A.P., Pleij C.W.A. & Westhoff E. (2005), RNA Structure: Pseudoknots. Encyclopedia of Life Sciences. ?: John Wiley & Sons, Ltd.boek
  • Roon A.M.M. van, Bink H.H.J., Plaisier J.R., Pleij C.W.A., Abrahams J.P. & Pannu N.S. (2004), Crystal structure of an empty capsid of turnip yellow mosaic virus, JOURNAL OF MOLECULAR BIOLOGY 341(5): 1205-1214.artikel in tijdschrift (refereed)
  • Meulewater F., Lipzig R. van, Gultyaev A.P., Pleij C.W.A., Damme D. van, Cornelissen M. & Eldik G. van (2004), Conservation of RNA structures enables TNV and BYDV 5' and 3' elements to cooperate synergistically in cap-independent translation, Nucleic Acids Research 32: 172-173.artikel in tijdschrift (refereed)
  • Girard G.A.O., Roussis A., Gultyaev A.P., Pleij C.W.A. & Spaink H.P. (2003), Structural motifs in the RNA encoded by the early nodulation gene enod40 of soybean, Nucleic Acids Research 31: 5003-5015.artikel in tijdschrift (refereed)
  • Girard G., Roussis A., Gultyaev A.P., Pleij C.W.A. & Spaink H.P. (2003), Structural motifs in the RNA encoded by the early modulation gene enod40 of soybean, Nucleic Acids Research 31: 5003-5015.artikel in tijdschrift (refereed)
  • Barends S., Bink H.H.J., Worm S.H.E. van den, Pleij C.W.A. & Kraal B. (2003), Entrapping Ribosomes for viral translation: tRNA mimicry as a molecular Trojan horse, Cell 112: 123-129.artikel in tijdschrift (refereed)
  • Bink H.H.J., Schirawski J., Haenni A.-L. & Pleij C.W.A. (2003), The 5'-proximal hairpin of Turnip Yellow Mosaic Virus RNA: Its role in translation and encapsidation, Journal of Virology 77: 7452-7458.artikel in tijdschrift (refereed)
  • Girard G.A.O., Roussis A., Gultyaev A.P., Pleij C.W.A. & Spaink H.P. (2003), Structural motifs in the RNA encoded by the early nodulation gene enod40 of soybean, Nucleic Acids Research 31: 5003-5015.artikel in tijdschrift (refereed)
  • Mathu S.G.J., Knudsen C.R., Duin J. van, Kraal B. & Pleij C.W.A. (2003), The 5'-proximal hairpin of turnip yellow mosaic virus RNA: Its role in translation and encapsidation, Journal of Virology 77: 7452-7458.artikel in tijdschrift (refereed)
  • Lipzig R. van, Gultyaev A.P., Pleij C.W.A., Montagu M. van, Cornelissen M. & Meulewaeter F. (2002), The 5' and 3' extremities of the satellite tobacco necrosis virus translational enhancer domain contribute differentially to stimulation of translation., RNA: A Publication of the RNA Society 8: 229-236.artikel in tijdschrift (refereed)
  • Barends S., Bjoerk K., Gultyaev A.P., Smit M.H. de, Pleij C.W.A. & Kraal B. (2002), Functional evidence for D- and T-loop interactions in tmRNA., FEBS Letters 514: 78-83.artikel in tijdschrift (refereed)
  • Charlier N., Leyssen P., Pleij C.W.A., Lemey P., Billoir F., Laethem K. van, Vandamme A.-M., Clercq E. de, Lamballerie X. de & Neyts J. (2002), Complete genome sequence of the Montana Myotis leukoencephalitis virus, phylogenetic analysis and comparative study of the 3' untranslated region of flaviviruses with no known vector., Journal of General Virology 83: 1875-1885.artikel in tijdschrift (refereed)
  • Smit M.H. de, Gultyaev A.P., Hilge M., Bink H.H.J., Barends S., Kraal B. & Pleij C.W.A. (2002), Structural variation and functional importance of a D-loop-T-loop interaction in valine-accepting tRNA-like structures of plant viral RNAs., Nucleic Acids Research 30(19): 4232-4240.artikel in tijdschrift (refereed)
  • Bink H.H.J., Hellendoorn K., Meulen J van der & Pleij C.W.A. (2002), Protonation on non-Watson-Crick basepairs and encapsidaion of Turnip Yellow Mosaic Virus RNA., Proceedings of the National Academy of Science of the United States of America 99(21): 13465-13470.artikel in tijdschrift (refereed)
  • Bink H.H.J., Hellendoorn K., Meulen J van der & Pleij C.W.A. (2002), Protonartion of non-Watson-Crick base pairs and encapsidation of turnip yellow mosaic virus RNA, Proceedings of the National Academy of Science of the United States of America 99(21): 13465-13470.artikel in tijdschrift
  • Nagel J.H.A. & Pleij C.W.A. (2002), Self-induced structural switches in RNA., Biochimie 84: 913-923.artikel in tijdschrift (refereed)
  • Bink H.H.J. & Pleij C.W.A. (2002), RNA-protein interaction in spherical viruses., Archives of Virology 174: 2261-2279.artikel in tijdschrift (refereed)
  • Gultyaev A.P., Batenburg F.H.D. van & Pleij C.W.A. (2002), Selective Pressures on RNA Hairpins In Vivo and In Vitro, Journal of Molecular Evoluation 54: 1-8.artikel in tijdschrift (refereed)
  • Nagel J.H.A., Gultyaev A.P., Öistämö K.J., Gerdes K. & Pleij C.W.A. (2002), A pH-jump approach for investigating secondary structure refolding kinetics in RNA, Nucleic Acids Research 30(13): e63.artikel in tijdschrift (refereed)
  • Batenburg F.H.D. van, Gultyaev A.P. & Pleij C.W.A. (2001), PseudoBase: structural information on RNA pseudoknots., Nucleic Acids Research 29: 194-195.artikel in tijdschrift (refereed)
  • Michiels P.J.A., Versleijen A.A.M., Verlaan P.W.G., Pleij C.W.A., Hilbers C.W. & Heus H.A. (2001), Solution structure of the pseudoknot of SRV-1 RNA, involved in ribosomal frameshifting., Journal of Molecular Biology 310(5): 1109-1123.artikel in tijdschrift (refereed)
  • Deiman A.L.M., Verlaan P.W.G. & Pleij C.W.A. (2000), In vitro transcription by different plant viral RNA polymerases: a comparison with the turnip yellow mosaic virus replicase., Journal of Virology 74: 264-271.artikel in tijdschrift (refereed)
  • Batenburg F.H.D. van, Gultyaev A.P., Pleij C.W.A., Ng J. & Oliehoek J. (2000), PseudoBase: A database with RNA pseudoknots., Nucleic Acids Research 28: 201-204.artikel in tijdschrift (refereed)
  • Koenig R., Pleij C.W.A. & Buettner G. (2000), Structure and variability of the 3' end of RNA 3 of Beet soil-borne pomovirus - a virus with uncertain pathogenic effects., Archives of Virology 145: 1173-1181.artikel in tijdschrift (refereed)
  • Koenig R., Pleij C.W.A. & Huth W. (2000), Genome properties of a new furovirus which is widely spread in cereal crops in Europe.. In: Sherwood J.L., Rush C.M. (Red.) Proceedings of the Fourth Symposium of the International Working Group on Plant Viruses with Fungal Vectors, Asilomar Conference Center, Monterey, California, October 5-8, 1999. 41-44.congresbijdrage
  • Gultyaev A.P., Batenburg F.H.D. van & Pleij C.W.A. (1999), An approximation of loop free energy values of RNA H-pseudoknots., RNA: A Publication of the RNA Society 5: 609-617.artikel in tijdschrift (refereed)
  • Bringloe D.H., Pleij C.W.A. & Coutts R.H.A. (1999), Mutation analysis of cis-elements in the 3'- and 5'-untranslated regions of satellite tobacco necrosis virus strain C RNA., Virology 264: 76-84.artikel in tijdschrift (refereed)
  • Nagel J.H.A., Gultyaev A.P., Gerdes K. & Pleij C.W.A. (1999), Metastable structures and refolding kinetics in hok mRNA of plasmid R1., RNA: A Publication of the RNA Society 5(11): 1408-1418.artikel in tijdschrift (refereed)
  • Koenig R., Pleij C.W.A. & Huth W. (1999), Molecular characterization of a new furovirus mainly infecting rye., Archives of Virology 144: 2125-2140.artikel in tijdschrift (refereed)
  • Poot R.A. drs., Worm S.H.E. van den, Pleij C.W.A. & Duin J. van (1998), Base complementarity in helix 2 of the central pseudoknot in 16S ribosomal RNA is essential for ribosome functioning., Nucleic Acids Research 26: 549-553.artikel in tijdschrift (refereed)
  • Gultyaev A.P., Batenburg F.H.D. van & Pleij C.W.A. (1998), Dynamic competition between alternative structures in viroid RNAs stimulated by an RNA folding algorithm., Journal of Molecular Biology 276: 43-55.artikel in tijdschrift (refereed)
  • Kolk M.H., Graaf M. van der, Wijmenga S.S., Pleij C.W.A., Heus H.A. & Hilbers C.W. (1998), NMR structure of a classical pseudoknot: Interplay of single- and double-stranded RNA., Science 280: 434-438.artikel in tijdschrift (refereed)
  • Deiman A.L.M., Koenen A.K., Verlaan P.W.G. & Pleij C.W.A. (1998), Minimal template requirements for initiation of minus strand synthesis in vitro by the RNA-dependent RNA polymerase of turnip yellow mosaic virus., Journal of Virology 72: 3965-3972.artikel in tijdschrift (refereed)
  • Bringloe D.H., Gultyaev A.P., Pelpel M., Pleij C.W.A. & Coutts R.H.A. (1998), The nucleotide sequence of satellite tobacco necrosis virus strain C and helper-assisted replication of wild-type and mutant clones of the virus., Journal of General Virology 79: 1539-1546.artikel in tijdschrift (refereed)
  • Gultyaev A.P., Batenburg F.H.D. van & Pleij C.W.A. (1998), RNA folding dynamics. Computer simulations by a genetic algorithm.. In: Leontis N.B., Santa Lucia, Jr. J. (Red.) Molecular modeling of nucleic acids. Washington, DC: American Chemical Society. 229-245.boekdeel
  • Koenig R., Pleij C.W.A., Beier C. & Commandeur U. (1998), Genome properties of beet virus Q, a new furo-like virus from sugarbeet, determined from unpurified virus., Journal of General Virology 79: 2027-2036.artikel in tijdschrift (refereed)
  • Kolk M.H., Graaf M. van der, Fransen C.T.M., Wijmenga S.S., Pleij C.W.A., Heus H.A. & Hilbers C.W. (1998), Structure of the 3'-hairpin of the TYMV pseudoknot: preformation in RNA folding., EMBO Journal 12: 7498-7504.artikel in tijdschrift (refereed)
  • Bringloe D.H., Gultyaev A.P., Pelpel M., Pleij C.W.A. & Coutts R.H.A. (1998), The nucleotide sequence of satellite tobacco necrosis virus strain C and helper-assisted replication of wild-type and mutant clones of the virus., Journal of General Virology 79: 1539-1546.artikel in tijdschrift (refereed)
  • Gultyaev A.P., Batenburg F.H.D. van & Pleij C.W.A. (1998), RNA folding dynamics: Computer simulations by a genetic algorithm.. In: Leontis N.B., SantaLucia J. (Red.) Molecular Modeling of Nucleic Acids.. Washington: Am. Chem. Soc.boekdeel
  • Gultyaev A.P., Batenburg F.H.D. van & Pleij C.W.A. (1998), Dynamic competition between alternative structures in viroid RNAs simulated by an RNA folding algorithm, Journal of Molecular Biology 276: 43-55.artikel in tijdschrift (refereed)

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