Jan Raap
Onderzoeker / gast
- Naam
- Dr. J. Raap
- Telefoon
- +31 71 527 4442
- j.raap@chem.leidenuniv.nl
Onderzoeker / gast
- Wiskunde en Natuurwetenschappen
- Leiden Institute of Chemistry
- LIC/Chemical Biology
- LIC/CB/Supramolecular & Biomat. Chem.
- Golysheva E.A., Boyle A.L., Biondi B., Ruzza P., Kros A., Raap J., Toniolo C. & Dzuba S.A. (2021), Probing the E/K peptide coiled-coil assembly by double electron-electron resonance and circular dichroism, Biochemistry 60(1): 19-30.
- Kumar P., Son M. van, Zheng T., Raap J., Kros A. & Huber M.I. (2018), Coiled-coil Formation of the Membrane-Fusion K/E Peptides Viewed by Electron Paramagnetic Resonance, PLOS One 13(1): e0191197.
- Milov A.D., Tsvetkov Y.D., Raap J., De Zotti M., Formaggio F. & Toniolo C. (2016), Conformation, self-aggregation, and membrane interaction of peptaibols as studied by pulsed electron double resonance spectroscopy, Journal of Peptide Science 106(1): 6-24.
- Rabe M., Aisenbrey C., Pluhackova K., De Wert V., Boyle A.L., Bruggeman D.F., Kirsch S.A., Böckmann R.A., Kros A., Raap J. & Bechinger B. (2016), A Coiled-Coil Peptide Shaping Lipid Bilayers upon Fusion, Biophysical Journal 111(10): 2162-2175.
- Boyle A., Zheng T., Bulacu M., Daudey G., Versluis F., Voskuhl J., Martelli G., Raap J., Sevink G.J.A. & Kros A. (2016), Adding complexity to peptide-mediated membrane fusion. [conferentie poster].
- Zheng T., Bulacu M.I., Daudey G.A., Versluis F., Voskuhl J., Martelli G., Raap J., Sevink G.J.A., Kros A. & Boyle A.L. (2016), A non-zipper-like tetrameric coiled coil promotes membrane fusion, RSC Advances 6(10): 7990-7998.
- Zheng T., Boyle A.L., Marsden H.R., Valdink D., Martelli G., Raap J. & Kros A. (2015), Probing coiled-coil assembly by paramagnetic NMR spectroscopy , Organic and Biomolecular Chemistry 13: 1159-1168.
- Steendam R.E., Benthem J.B. van, Huijs M.E., Meekes H., Enckevort J.P. van, Raap J., Rutjes P.J.T. & Vlieg E. (2015), Deracemization controlled by reaction-induced nucleation: Viedma ripening as a safety catch for total spontaneous resolution, Crystal Growth & Design 15: 3917-3921.
- Steendam R.E., Dickhout J., Enckevort J.P., Meekes H., Raap J., Rutjes P.J.T. & Vlieg E. (2015), Linear deracemization kinetics during Viedma ripening: autocatalysis overruled by chiral additives, Crystal Growth & Design 15: 1975-1982.
- Steendam R.R.E., Brouwer M.C.T., Huijs E.M.E., Kulka M.W., Meekes H., Van Enckevort W.J.P., Raap J., Rutjes F.P.J.T. & Vlieg E. (2014), Enantiopure Isoindolinones through Viedma Ripening, Chemistry: a European Journal 20(42): 13527-13530.
- Son M. van, Zheng T., Kumar P., Valdink D., Raap J., Kros A. & Huber M. (2014), Towards Artificial Membrane Fusion: Ek-Peptides, the Coilied-Coil Zipper, Biophysical Journal 106(2): 506A-506A.
- Steendam R.R.E., Verkade J.M.M., Benthum T.J.B. van, Meekes H., Enckevort W.J.P., Raap J., Rutjes F.P.J.T. & Vlieg E. (2014), Emergence of single-molecular chirality from achiral reactants, Nature Communications 5: 5534.
- Dzuba Sergei A. & Raap Jan (2013), Spin-Echo Electron Paramagnetic Resonance (EPR) Spectroscopy of a Pore-Forming (Lipo)Peptaibol in Model and Bacterial Membranes, Chemistry and Biodiversity 10(5): 864-875.
- Steendam Rene R.E., Harmsen Bram, Meekes Hugo, Van Enckevort Willem J.P., Kaptein Bernard, Kellogg Richard M., Raap Jan, Rutjes Floris P.J.T. & Vlieg Elias (2013), Controlling the Effect of Chiral Impurities on Viedma Ripening, Crystal Growth & Design 13(11): 4776-4780.
- Syryamina V.N., Zotti M. de, Peggion C., Formaggio F., Toniolo C., Raap J. & Dzuba S.A. (2012), A Molecular View on the Role of Cholesterol upon Membrane Insertion, Aggregation, and Water Accessibility of the Antibiotic Lipopeptide Trichogin GA IV As Revealed by EPR, The Journal of Physical Chemistry B 116: 5653-5660.
- Syryamina V.N., Isaev N.P., Peggion C., Formaggio F., Toniolo C., Raap J. & Dzuba S.A. (2010), Small-Amplitude Backbone Motions of the Spin-Labeled Lipopeptide Trichogin GA IV in a Lipid Membrane As Revealed by Electron Spin Echo, The Journal of Physical Chemistry B 114: 12277-12283.
- Milov A.D., Samoilova R.I., Shubin A.A., Gorbunova E.Yu., Mustaeva L.G., Ovchinnikova V., Raap J. & Tsvetkov Y.D. (2010), Self-Aggregation and Orientation of the Ion Channel-Forming Zervamicin IIA in the Membranes of ePC Vesicles Studied by cw EPR and ESEEM Spectroscopy, Applied Magnetic Resonance 38(1): 75-84.
- Milov A.D., Samoilova R.I., Tsvetkov Y.D., De Zotti M., Formaggio F., Toniolo C., Handgraaf J.-W. & Raap J. (2009), Structure of Self-Aggregated Alamethicin in ePC Membranes Detected by Pulsed Electron-Electron Double Resonance and Electron Spin Echo Envelope Modulation Spectroscopies, Biophysical Journal 96(8): 3197-3209.
- Salnikov E.S., Friedrich H., Li X., Bertani P., Reissmann S., Hertweck C., O’Neil J.D.J., Raap J. & Bechinger B. (2009), Structure and Alignment of the Membrane-Associated Peptaibols Ampullosporin A and Alamethicin by Oriented 15N and 31P Solid-State NMR Spectroscopy, Biophysical Journal 96(1): 86-100.
- Salnikov E.S., De Zotti M., Formaggio F., Li X., Toniolo C., O’Neil J.D.J., Raap J., Dzuba S.A. & Bechinger B. (2009), Alamethicin Topology in Phospholipid Membranes by Oriented Solid-state NMR and EPR Spectroscopies: a Comparison, Journal of Physical Chemistry B 113(10): 3034-3042.
- Milov A.D., Samoilova R.I., Tsvetkov Y.D., De Zotti M., Toniolo C. & Raap J. (2008), PELDOR Conformational Analysis of bis-Labeled Alamethicin Aggregated in Phospholipid Vesicles, Journal of Physical Chemistry B 112(43): 13469-13472.
- Salnikov E.S., Bertani P., Raap J. & Bechinger B. (2008), Analysis of the amide 15N chemical shift tensor of the Cα tetrasubstituted constituent of membrane-active peptaibols, the α-aminoisobutyric acid residue, compared to those of di- and tri-substituted proteinogenic amino acid residues, Journal of Biomolecular NMR 45(4): 373-387.
- Weidema A.F., Kropacheva T.N., Raap J. & Ypey D.L. (2007), Membrane Permeabilization of a Mammalian Neuroendocrine Cell Type (PC12) by the Channel-Forming Peptides Zervamicin, Alamethicin, and Gramicidin, Chemistry and Biodiversity 4: 1347-1359.
- Milov A.D., Tsvetkov Y.D., Gorbunova E.Y., Mustaeva L.G., Ovchinnikova T.V., Handgraaf J.W. & Raap J. (2007), Solvent effects on the secondary structure of membrane active Zervamicin determined by PELDOR specroscopy, Chemistry and Biodiversity 4: 1243-1255.
- Milov A.D., Samoilova M.I., Tsvetkov Y.D., Jost M., Peggion C., Formaggio F., Crisma M., Toniolo C., Handgraaf J.W. & Raap J. (2007), Supramolecular structure of self-assembling alamethicin analog studied by ESR and PELDOR, Chemistry and Biodiversity 4: 1275-1298.
- Kropacheva T.N. & Raap J. (2007), Enzymatic reaction in a vesicular microreactor: peptaibol facilitated substrate transport, Chemistry and Biodiversity 4: 1388-1394.
- Milov A.D., Samoilova M.I., Tsvetkov Y.D., Formaggio F., Toniolo C. & Raap J. (2007), Self-Aggregation of spin-labeled alamethicin in ePC vesicles studied by pulsed electron-electron double resonance, Journal of the American Chemical Society 129: 9260-9261.
- Milov A.D., Samoilova R.I., Tsvetkov Y.D., Jost M., Peggion C., Formaggio F., Toniolo C., Crisma M., Handgraaf J.-W. & Raap J. (2007), Supramolecular Structure of Self-assembling Alamethicin Analog Studied by ESR and PELDOR, Chemistry and Biodiversity 4: 1275-1298.
- Milov A.D., Samoilova R.I., Tsvetkov Y.D., Formaggio F., Toniolo C. & Raap J. (2007), Self-Aggregation of Spin-Labeled Alamethicin in ePC Vesicles Studied by Pulsed Electron-Electron Double Resonance, Journal of the American Chemical Society 129(30): 9260-9261.
- Kropacheva T.N., Salnikov E.S., Nguyen H.H., Reissmann S., Yakimenko Z.A., Tagaev A.A., Ovchinnikova T.V. & Raap J. (2005), Membrane association and activity of 15/16-membered peptide antibiotics: Zervamicin IIB, ampullosporin A and antiamoebin I, Biochimica et Biophysica Acta 1715: 6-18.
- Raap J., Erkelens K., Ogrel A., Skladnev DA & Brückner H. (2005), Fungal biosynthesis of non‐ribosomal peptide antibiotics and α, α‐dialkylated amino acid constituents, JOURNAL OF PEPTIDE SCIENCE 11: 331-338.
- Siebum A.H.G., Tsang R.K.F., Steen R. van der, Raap J. & Lugtenburg J. (2004), Synthesis of (epsilon-C-13-,epsilon N-15)-enriched L-lysine - Establishing schemes for the preparation of all possible C-13 and N-15 isotopomers of L-lysine, L-ornithine, and L-proline, European Journal of Organic Chemistry 2004(21): 4391-4396.
- Siebus A.H.G., Woo W., Raap J. & Lugtenburg J. (2004), Access to any site-directed isotopomer of methionine, selenomethionine, cysteine, and selenocysteine - Use of simple, efficient modular synthetic reaction schemes for isotope incorporation, European Journal of Organic Chemistry 2004(13): 2905-2913.
- Milov A.D., Tsvetkov Y.D., Formaggio F., Oancea S., Toniolo C. & Raap J. (2003), Aggretation of spin labeld trichogin GA IV dimers: Distance disribution between spin labels in frozen solutions by PELDOR data, Journal of Physical Chemistry B 107: 13719-13727.
- Alia A., Hulsebosch B., Gorkom H.J. van, Raap J., Lugtenburg J., Matysik J., Groot H.J.M. de & Gast P. (2003), Probing the electronic structure of tyrosine radial Y-D (center dot) in photosystem II by EPR spectroscopy using site specific isotope labelling in Spirodela oligorrhiza, Chemical Physics 294(3): 459-469.
- Milov A.D., Tsvetkov Y.D., Formaggio F., Crisma M., Toniolo C. & Raap J. (2003), Self-assembling and membrane modifying properties of a lipopeptaibol studied by CW-ESR and PELDOR spectroscopies, JOURNAL OF PEPTIDE SCIENCE 9: 690-700.
- Ouwerkerk N., Steenweg M., Ruijter M. de, Brouwer J., Boom J.H. van, Lugtenburg J. & Raap J. (2002), One-pot two-step enzymatic coupling of pyrimidine bases to 2-deoxy-D-ribose-5-phosphate. A new strategy in the synthesis of stable isotope labeled deoxynucleosides, Journal of Organic Chemistry (JOC) 67(5): 1480-1489.
- Schulten E.A.M., Matysik J., Alia A., Kiihne S.R., Raap J., Lugtenburg J., Gast P., Hoff A.J. & Groot H.J.M. de (2002), 13C MAS NMR and photo-CIDNP reveal a pronounced assymetry in the electron ground state of the special pair of Rhodobacter spearoides reaction centers, Biochemistry 41(27): 8708-8717.
- Milov A.D., Tsvetkov Yu.D., Gorbunova E.Y., Mustaeva L.G., Ovchinnikova T.V. & Raap J. (2002), Self-aggregation properties of spin-labeled Zervamicin IIa as studied by PELDOR spectroscopy, Biopolymers 64: 328-336.
- Boer I. de, Bosman L., Raap J., Oschkinat H. & Groot H.J.M. de (2002), 2D13C-13C MAS NMR Correlation spectroscopy with mixing by true 1H spin diffusion reveals long-range intermolecular distance restraints in ultra high magnetic field, Journal of Magnetic Resonance 157(2): 286-291.
- Shenkarev Z.O., Balashova T.A., Efremov R.G., Yakimenko Z.A., Ovchinnikova T.V., Raap J. & Arseniev A.S. (2002), Spacial structure of zervamicin IIB bound to DPC micelles: implications for voltage-gating, Biophysical Journal 82: 762-771.
- Rossum B.J. van, Schulten E.A.M., Raap J., Oschkinat H. & Groot H.J.M. de (2002), A 3-D structural model of solid self-assembled chlorophyll a/H2O from multispin labeling and MAS NMR 2-D dipolar correllation spectroscopy in high magnetic field, Journal of Magnetic Resonance 155(1): 1-14.
- Ouwerkerk N., Boom J.H. van, Lugtenburg J. & Raap J. (2002), Synthesis of [1',2',5',2-13C4]-2'-deoxy-D-adenosine by a chemoenzymatic strategy to enable labelling of any of the 215 carbon-13 and nitrogen-15 isotopomers, European Journal of Organic Chemistry 2002(14): 2356-2362.
- Matysik J., Schulten E., Alia A., Gast P., Raap J., Lugtenburg J., Hoff A.J. & Groot H.J.M. de (2001), Photo-CIDNP 13C magic angle spinning NMR on bacterial reaction centres: exploring the electronic structure of the special pair and its surroundings, Biological Chemistry 382(8): 1271-1276.
- Kandori H., Yamazaki Y., Shichida Y., Raap J., Lugtenburg J., Belenky M. & Herzfeld J. (2001), Tight Asp-85-Thr-89 Association during the Pump Switch of Bacteriorhodopsin, Proceedings of the National Academy of Sciences 98(4): 1571-1576.
- Milov A.D., Tsvetkov Yu.D., Formaggio F., Crisma M., Toniolo C. & Raap J. (2001), The Secondary Structure of a Membrane-Modifying paptide in a Supramolecular Assembly Studied by PELDOR and CW-ESR Spectroscopies, Journal of the American Chemical Society 123: 3784-3789.
- Soede-Huijbregts C., Laren M. van, Hulsbergen F.B., Raap J. & Lugtenburg J. (2001), Improved Specific Synthesis of [1'-15N]- and [3'-15N]L-Histidine, Journal of Labelled Compounds and Radiopharmaceuticals 44(12): 831-841.
- Alia A., Matysik J., Soede-Huijbregts C., Baldus M., Raap J., Lugtenburg J., Gast P., Gorkom H.J. van, Hoff A.J. & Groot H.J.M. de (2001), Ultrahigh field MAS NMR dipolar correlation spectroscopy of the histidine residues in light-harvesting complex II from photosynthetic bacteria levels partial internal charge transfer in the B850/his complex, Journal of the American Chemical Society 123(20): 4803-4809.
- Milov A.D., Yu Yu, Tsvetkov D.E., Formaggio F., Crisma M., Toniolo C., Millhauser G.L. & Raap J. (2001), Self-Assembling Properties of a Membrane-Modifying Lipopeptaibol in Weakly Polar Solvents Studied by CW ESR, Journal of Physical Chemistry B 105: 11206-11213.
- Bechinger B., Skladnev DA, Ogrel A., Rogozhkina AV, Ovchinnikova T.V., O'Neill JDJ & Raap J. (2001), 15N and 31P Solid State NMR Investigations on the Orientation of Zervamicin II and Alamethicin in Phosphatidylcholine Membranes, Biochemistry 40: 9428-9437.
- Griffiths J.M., Bennett A.E., Engelhard M., Siebert F., Raap J., Lugtenburg J., Herzfeld J. & Griffin R.G. (2000), Structural Investigation of the Active Site in Bacteriorhodopsin: Geometric Constraints in the Roles of Asp-85 and Asp-212 in the Proton-Pumping Mechanism from Solid State NMR, Biochemistry 39(2): 362-371.
- Balashova T.A., Shenkarev Z.O., Tagaev A.A., Ovchinnikova T.V., Raap J. & Arseniev A.S. (2000), NMR Structure of the Channel-Former Zervamicin IIB in Isotropic Solvents, FEBS Letters 466: 333-336.
- Kandori H., Kinoshita N., Yamazaki Y., Maeda A., Shichida Y., Needleman R., Lanyi J.K., Bizounok M., Herzfeld J., Raap J. & Lugtenburg J. (2000), Local and Distant Protein Structural Changes on Photoisomerization of the Retinal in Bacteriorhodopsin, Proceedings of the National Academy of Sciences 97(9): 4643-4648.
- Milov A.D., Tsvetkov Yu.D., Formaggio F., Crisma M., Toniolo C. & Raap J. (2000), Self-Assembling Properties of Membrane-Modifying Peptides Studied by PELDOR and CW-ESR Spectroscopies, Journal of the American Chemical Society 122(16): 3843-3848.
- Ouwerkerk N., Boom J.H. van, Lugtenburg J. & Raap J. (2000), Chemo-Enzymatic Synthesis of Thymidine 13C-Labelled in the 2'-Deoxyribose Moiety, European Journal of Organic Chemistry 2000(5): 861-866.
- Ogrel A., Shvets V., Sevenster P., Broxterman Q.B. & Raap J. (2000), Synthesis of 15N-Labelled D-Isovaline and alpha-Aminoisobutyric Acid, European Journal of Organic Chemistry : 857-859.
- Creemers A.F.L., Klaassen C.H.W., Bovee-Geurts P., Kelle R., Kragl U., Raap J., Grip W.J. de, Lugtenburg J. & Groot H.J.M. de (1999), Solid state N-15 NMR evidence for a complex Schiff base counterion in the visual G-protein-coupled receptor rhodopsin, Biochemistry 38(22): 7195-7199.
- Raap J., Nieuwenhuis S.A.M., Creemers A.F.L., Hexspoor S., Kragl U. & Lugtenburg J. (1999), Synthesis of Isotopically Labeled L-Phenylalanine and L-Tyrosine, European Journal of Organic Chemistry 1999(10): 2609-2621.
- Kropacheva T.N. & Raap J. (1999), Voltage-Dependent Interaction of the Peptaibol Antibiotic Zervamicin II with Phospholipid Vesicles, FEBS Letters 460: 500-504.
- Rossum B.J. van, Steensgaard D., Holzwarth A.R., Soede-Huijbregts C., Schaffner K., Raap J., Lugtenburg J., Gast P., Hoff A.J. & Groot H.J.M. de (1999), Magic angle spinning NMR of Photosynthetic components. Greve J., Puppels G.J. & Otto C. (red.), Spectroscopy of Biological Molecules: New Directions. 8th European Conference on the Spectroscopy of Biological Molecules 29 augustus 1999 - 2 september 1999. Spectroscopy of Biological Molecules: New Directions. Dordrecht: Springer. 201-204.
- Grip W.J. de, Lange F. de, Klaassen C.H.W., Verdegem P.J.E., Wallace-Williams S., Creemers A.F.L., Bergo V., Bovee-Geurts P.H.M., Raap J., Rothschild K.J., Groot H.J.M. de & Lugtenburg J. (1999), Photoactivation of rhodopsin: Interplay between protein and chromophore Rhodopsins and Phototransduction. In: Takeuchi I., Bock G. & Goode J.A. (red.), Rhodospins and Phototransduction: Rhodospins and Phototransduction: Novartis Symposium 224. Novartis Foundation Symposia nr. 224: Wiley. 102-123.
- Kandori H., Kinoshita N., Yamazaki Y., Maeda A., Shichida Y., Needleman R., Lanyi J.K., Bizounok M., Herzfeld J., Raap J. & Lugtenburg J. (1999), Structural Change of Threonine 89 upon Photoisomerization in Bacteriorhodopsin as Revealed by Polarized FTIR Spectroscopy, Biochemistry 38(30): 9676-9683.
- Milov A.D., Maryasov A.G., Tsvetkov Yu.D. & Raap J. (1999), Pulsed ELDOR in Spin-Labelled Polypeptides, Journal of Physical Letters 303: 135.
- Rossum B.-J. van, Boender G.-J, Mulder F.M., Raap J., Balaban T.S., Holzwarth A.R., Schaffner K., Prytulla S., Oschkinat H & Groot H.J.M. de (1998), Multidimensional CP-MAS 13C NMR of uniformly enriched chlorophyll, Spectrochimica Acta Part A : Molecular and Biomolecular Spectroscopy 54(9): 1167-1176.
- Schulten E.A.M., Rossum B.J. van, Ashurst J., Oschkinat H., Raap J. & Groot H.J.M. de (1998), MAS NMR Dipolar Correlation Spectroscopy of partially deuterated 13C-labelled Chlorophyll a, Proceedings of the XIth International Congress on Photosynthesis : .
- Toropov Yu.V., Dzuba S.A., Tsvetkov Yu.D., Monaco V., Formaggio F., Crisma M., Toniolo C. & Raap J. (1998), Molecular Dynamics of TOAC Spin Labelled Peptaibols Studied in Glassy Liquid Using Echo-Detected EPR Spectroscopy, Applied Magnetic Resonance 15: 237.
- Ogrel A., Ogrel S., Shvets V. & Raap J. (1998), Synthesis of the 15N-Gln-11 Labelled Peptaibol Antibiotic Zervamicin IIB, Letters in Peptide Science 5: 175.
- Soede-Huijbregts C., Cappon J.J., Boender G.-J, Raap J., Gast P., Hoff A.J., Lugtenburg J. & Groot H.J.M. de (1998), 15N MAS NMR spectroscopy of [n-25N] and [t-15N] histidine labelled bacterial photosynthetic reaction centers. In: Garab G. (red.), Photosynthesis: Mechanisms and Effects. Dordrecht, The Netherlands: Kluwer Academic Publishers. 759-762.
- Nieuwenhuis S.A.M., Hulsebosch R.J., Raap J., Gast P., Lugtenburg J. & Hoff A.J. (1998), Structure of the Y_D Tyrosine Radical in photosystem II - Determination of the orientation of the Phenoxyl Ring by Enantioselective deuteration of the Methylene Group, Journal of the American Chemical Society 120(4): 829-830.
- Hu J.G., Sun B.Q., Bizounok M., Hatcher M.E., Lansing J.C., Raap J., Verdegem P.J.E., Lugtenburg J., Griffin R.G. & Herzfeld J. (1998), Early and Late M Intermediates in the Bacteriorhodopsin Photocycle: A Solid State NMR Study, Biochemistry 37(22): 8088-8096.
- Liu X.M., Lee M.J., Coleman M., Rath P., Nilsson A., Fischer W.B., Bizounok M., Herzfeld J., Karstens W.F.J., Raap J., Lugtenburg J. & Rothschild K.J. (1998), Detection of Threonine Structural Changes upon Formation of the M-Intermediate of Bacteriorhodopsin: Evidence for Assigment to Thr-89, Biochimica et Biophysica Acta. Bioenergetics 1365(3): 363-372.
- Maryasov A.G., Tsvetkov Yu.D. & Raap J. (1998), Weakly Coupled Radical Pairs in Solids: ELDOR in ESE Structure Studies, Applied Magnetic Resonance 14: 101.
- Alia A., Matysik J., Soede-Huijbregts C., Gast P., Raap J., Lugtenburg J., Groot H.J.M. de & Gorkom H.J. van (1998), Selective 15N-isotope labelling of histidines in PSII reaction centers of Spirodela oligorrhiza. In: Garab G. (red.), Photosynthesis: Mechanisms and Effects nr. II. Dordrecht, The Netherlands: Kluwer Academic Publishers. 1009-1012.
- Ogrel A., Bloemhoff W., Lugtenburg J. & Raap J. (1997), Total synthesis of zervamicin IIB and its deuterium-labelled analogues, Journal of Peptide Science 3(3): 193-208.
- Ogrel A., Heerma W., Versluis K., Lugtenburg J. & Raap J. (1997), Mass spectrometric analysis of site specific deuterated zervamicins, Analytical Letters 30(15): 2827-2846.
- Egorova-Zachernyuk A., Rossum B. van, Boender G.J., Franken E., Ashurst J., Raap J., Gast P., Hoff A.J. Oschkinat H. & Groot H.J.M. de (1997), Characterization of pheophytin ground states in Rhodobacter sphaeroides R26 photosynthetic reaction centers from multispin pheophytin enrichment and 2-D 13C MAS NMR dipolar correlation spectroscopy, Biochemistry 36(24): 7513-7519.
- Ogrel A., Bloemhoff W., Lugtenburg J. & Raap J. (1997), Synthesis of the isotopically labelled C-terminal fragment of zervamicin: an approach to the synthesis of Aib-containing peptides, European Journal of Organic Chemistry 1997(1): 41-47.
- Hulsebosch R.J., Brink J.S. van den, Nieuwenhuis S.A.M., Gast P., Raap J., Lugtenburg J. & Hoff A.J. (1997), Electronic structure of the neutral tyrosine radical in frozen solution. Selective H-2-, C-13-, and O-17-isotope labeling and EPR spectroscopy at 9 and 35 GHz, Journal of the American Chemical Society 119(37): 8685-8694.
- Rossum B.J. van, Wachtveitl J., Raap J., Hoef K. van der, Gast P., Lugtenburg J., Oesterhelt D. & Groot H.J.M. de (1997), 13C MAS NMR evidence for structural similarity of L162YL mutant and Rhodobacter sphaeroides R26 RC, despite widely different cytochrome c(2)-mediated re-reduction kinetics of the oxidized primary donor, Spectrochimica Acta Part A : Molecular and Biomolecular Spectroscopy 53(12): 2201-2208.
- Egorova-Zachernyuk T.A., Shvets V.I., Versluis K., Heerma W., Creemers A.F.L., Nieuwenhuis S.A.M., Lugtenburg J. & Raap J. (1996), Preparation of site-specific isotopically labelled zervamicins, the antibiotic peptaibols produced by emericellopsis salmosynnemata, Journal of Peptide Science 2(6): 341-350.
- Kropacheva T.N., Liemt W.B.S. van, Raap J., Lugtenburg J. & Hoff A.J. (1996), Hydrogen-bonding effect on C-13 and proton hyperfine couplings of [4-C-13]-labeled ubisemiquinones in vitro, The Journal of Physical Chemistry 100(24): 10433-10442.
- Raap J., Wolthuis W.N.E. & Hehenkamp J.J.J. Lugtenburg J. (1995), Enantioselective synthesis of isotopically labeled alpha-amino-acids Preparation of specifically 13C-labelled L-lysines, Amino Acids 8: 171-186.
- Boender G.J., Raap J., Prytulla S., Oschkinat H. & Groot H.J.M. de (1995), MAS NMR structure refinement of uniformly 13C enriched chlorophyll a/water aggregates with 2D dipolar correlation spectroscopy, Chemical Physics Letters 237(5-6): 502-508.
- Boender G.J., Balaban T.S., Holzwarth A.R., Schaffner K., Raap J., Prytulla S., Oschkinat H. & Groot H.J.M. de (1995), Comparison of the stacking of chlorophylls in chlorosomes versus aggregates of bacteriochlorophyll C and chlorophyll A using 2-D MAS NMR spectroscopy. Mathis P. (red.), Photosynthesis : from light to biosphere.. Xth International Photosynthesis Congress 20 augustus 1995 - 25 augustus 1995. PHOTOSYNTHESIS: FROM LIGHT TO BIOSPHERE, VOL I nr. 1. Dordrecht: Kluser Academic Publishers. 347-350.
- Shochat S., Gast P., Hoff A.J., Boender G.J., Leeuwen S. van, Liemt W.B.S. van, Vijgenboom E., Raap J., Lugtenburg J. & Groot H.J.M. de (1995), 13C MAS NMR evidence for a homogeneously ordered environment of tyrosine M210 in reaction centres of Rhodobacter sphaeroides, Spectrochimica Acta Part A : Molecular and Biomolecular Spectroscopy 51(1): 135-144.
- Yamazaki Y., Hatanaka M., Kandori H., Sasaki J., Karstens W.F.J., Raap J., Lugtenburg J., Bizounok M., Herzfeld J., Needleman R., Lanyi J.K. & Maeda A. (1995), Water structural changes at the proton uptake site (the Thr46-Asp96 domain) in the L intermediate of bacteriorhodopsin, Biochemistry 34(21): 7088-7093.
- Karstens W.F.J., Berger H.J.F.F., Haren E.R. van, Lugtenburg J. & Raap J. (1995), Enantioselective synthesis of isotopically labelled L-alpha-amino acids prepapration of 13C-, 18O- and 2H-labelled L-serines and L-threonines, Journal of Labelled Compounds and Radiopharmaceuticals 36(11): 1077-1096.
- Cappon J.J. Witters K.D. Baart J., Verdegem P.J.E., Hoek A.C., Luiten R.J.H., Raap J. & Lugtenburg J. (1994), Synthesis of L-histidine specifically labeled with stable isotopes, Recueil des Travaux Chimiques des Pays-Bas = Journal of the Royal Netherlands Chemical Society 113(6): 318-328.
- Lakshmi K.V., Farrar M.R., Raap J., Lugtenburg J., Griffin R.G. & Herzfeld J. (1994), Solid state 13C and 15N NMR investigations of the N intermediate of bacteriorhodopsin, Biochemistry 33(30): 8853-8857.
- Ogrel A., Valilenko I.A., Lugtenburg J. & Raap J. (1994), Enzymatic synthesis of specifically 2H-labelled L-glutamic acids and 2H-, 15N-, 13C-labelled L-glutamines on a preparative scale, Recueil des Travaux Chimiques des Pays-Bas 113(7-8): 369-375.
- Brink J.S. van den, Spoyalov A.P., Gast P., Liemt W.B.S. van, Raap J., Lugtenburg J. & Hoff A.J. (1994), Asymmetric binding of the primary acceptor quinone in reaction centers of the photosynthetic bacterium rhodobacter-sphaeroides R26, probed with Q-band (35 GHz) EPR spectroscopy, FEBS Letters 353(3): 273-276.
- Lakshmi K.V., Auger M., Raap J., Lugtenburg J., Griffin R.G. & Herzfeld J. (1993), Internuclear distance measurement in a reaction intermediate: solid-state carbon-13 NMR rotational resonance determination of the Schiff-base configuration in the M-photointermediate of bacteriorhodopsin, Journal of the American Chemical Society 115(18): 8515-8516.
- Ames J.B., Ros M., Raap J., Lugtenburg J. & Mathies R.A. (1992), Time-resolved ultraviolet resonance Raman studies of protein structure: application to bacteriorhodopson, Biochemistry 31(23): 5328-5334.
- Ames J.B., Raap J., Lugtenburg J. & Mathies R.A. (1992), Resonance Raman study of halorhodopsin photocycle kinetics, chromophore structures, and chloride-pumping mechanism, Biochemistry 31(50): 12546-12554.
- Fischer M.R., Groot H.J.M. de, Raap J., Winkel C., Hoff A.J. & Lugtenburg J. (1992), Carbon-13 magic angle spinning NMR study of the light-induced and temperature-dependent changes in Rhodbacter sphaeroides R26 reaction centers enriched in [4'-13C]tyrosine, Biochemistry 31(45): 11038-11049.
- Cappon J.J., Walle G.A.M. van der, Verdegem P.J.E., Raap J. & Lugtenburg J. (1992), Synthesis of specifically stable-isotope_labeled l-proline via L-glutamic acid, Recueil des Travaux Chimiques des Pays-Bas = Journal of the Royal Netherlands Chemical Society 111(12): 517-523.
- Cappon J.J., Baart J., Walk G.A.M. van der, Raap J. & Lugtenburg J. (1991), Chemo-enzymatic synthesis of specifically stable-isotope labelled L-glutamic acid and 2-oxoglutaric acid, Recueil des Travaux Chimiques des Pays-Bas = Journal of the Royal Netherlands Chemical Society 110(5): 158-166.
- Raap J., Winkel C., Wit A.H.M. de, Houten A.H.H. van, Hoff A.J. & Lugtenburg J. (1990), Mass-spectrometric determination of isotopically labeled tyrosines and tryptophans in photosynthetic reaction centers of Rhodobacter sphaeroides R-26, Analytical Biochemistry 191(1): 9-15.
- Groot H.J.M. de, Raap J., Winkel C., Hoff A.J. & Lugtenburg J. (1990), Magic-angle spinning 13C NMR with atomic resolution of a photosynthetic reaction center enriched in [4'-13]tyrosine, Chemical Physics Letters 169(4): 307-310.
- Ames J.B., Fodor S.P.A., Gebhard R., Raap J., Berg E.M.M. van den, Lugtenburg J. & Mathies R.A. (1989), Bacteriorhodopsin's M412 intermediate contains a 13-cis,14-s-trans,15-anti-retinal Schiff base chromophore, Biochemistry 28(9): 3681-3687.