Jaco Slingerland
Onderzoeker / gast
- Naam
- Dr. C.J. Slingerland
- Telefoon
- +31 71 527 2727
- c.j.slingerland@biology.leidenuniv.nl
Supervisor(s)
Onderzoeker / gast
- Wiskunde en Natuurwetenschappen
- Instituut Biologie Leiden
- IBL Microbial Sciences
- Slingerland C.J. (28 februari 2024), New polymyxin antibiotics for old problems : addressing nephrotoxicity and resistance (Dissertatie. Institute of Biology Leiden (IBL), Faculty of Science, Leiden University). Promotor(en) en copromotor(en): Martin N.I., Innocenti P.
- Slingerland C.J., Wesseling C.M.J., Innocenti P., Westphal K.G.C., Masereeuw R. & Martin N.I. (2022), Synthesis and evaluation of polymyxins bearing reductively labile disulfide-linked lipids, Journal of Medicinal Chemistry 65(23): 15878-15892.
- Wade N., Wesseling C.M.J., Innocenti P., Slingerland C.J., Koningstein G.M., Luirink J. & Martin N.I. (2022), Synthesis and structure–activity studies of β-barrel assembly machine complex inhibitor MRL-494, ACS Infectious Diseases 8(11): 2242-2252.
- Slingerland C.J., Kotsogianni A.I., Wesseling C.M.J. & Martin N.I. (2022), Polymyxin stereochemistry and its role in antibacterial activity and outer membrane disruption, ACS Infectious Diseases 8(12): 2396-2404.
- Wood T.M., Slingerland C.J. & Martin N.I. (2021), A convenient chemoenzymatic preparation of chimeric macrocyclic peptide antibiotics with potent activity against gram-negative pathogens, Journal of Medicinal Chemistry 64(15): 10890–10899.
- Wesseling C.M.J., Slingerland C.J., Veraar S., Lok S. & Martin N.I. (2021), Structure-activity studies with bis-amidines that potentiate Gram-positive specific antibiotics against Gram-negative pathogens, ACS Infectious Diseases 7(12): 3314-3335.
- Groesen E. van, Slingerland C.J., Innocenti P., Mihajlovic M., Masereeuw R. & Martin N.I. (2021), Vancomyxins: vancomycin-polymyxin nonapeptide conjugates that retain anti-gram-positive activity with enhanced potency against gram-negative strains, ACS Infectious Diseases 7(9): 2746–2754.
- Wesseling C.M.J., Wood T.M., Slingerland C.J., Bertheussen K., Lok S. & Martin N.I. (2021), Thrombin-derived peptides potentiate the activity of Gram-positive-specific antibiotics against Gram-negative bacteria, Molecules 26(7): 1954.