
Nathaniel Martin
Professor Biological chemistry
- Name
- Prof.dr. N.I. Martin
- Telephone
- +31 71 527 2954
- n.i.martin@biology.leidenuniv.nl
The Martin group is part of the Institute of Biology Leiden (IBL) at Leiden University. We apply (bio)organic chemistry and chemical biology-based approaches to address biologically interesting and medically relevant questions. Our research interests are broad and include investigating new molecular strategies for combatting infectious disease as well as developing innovative tools with which to study epigenetic processes. The Martin group is comprised of a number of Postdocs, PhDs, and Master/Bachelor student researchers. We also regularly host foreign students who visit Leiden for a research internship abroad (for example Erasmus students). Feel free to contact us if you are interested in joining the group.
More information about Nathaniel Martin
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Brief summary of research over last 5 years
Prof. Martin leads an independent research group with a major focus on applying bioorganic chemistry in pursuit of novel anti-infectives and molecular tools to study epigenetic processes. In recent years he has succeeded in acquiring external research funding, most notably the ERC Consolidator Grant (€2,0M) and the NWO VIDI grant (€800k, both awarded to the top 10% of researchers in their peer group). Recent output from the Martin group includes contributions made to understanding fundamental principles of antibiotic mechanism (MedChemComm 2018, Angew. Chem. Int. Ed. 2017, Biochemistry 2016, J. Med. Chem. 2016), bacterial replication (PLoS ONE 2016, J. Biol. Chem. 2014), and antibiotic resistance (ACS Infect. Dis. 2018, Mol. Cell. Proteomics 2018. ACS Infect. Dis. 2017). The group has also developed new synthetic strategies for the preparation of a range of novel anti-infective compounds (Molecules 2018, Chem. Sci. 2017, J. Am. Chem. Soc. 2015, J. Med. Chem. 2014) and biologically active peptides (ChemBioChem 2018, Proc. Natl. Acad. Sci. U.S.A. 2017, Org. Biomol. Chem. 2014). More information about the group and our research can be found at our website.
International visibility, activities, prizes, scholarships etc.
Prof. Martin conducted his PhD studies at the University of Alberta (Canada) under the guidance of Prof. John Vederas. Upon completing his PhD in 2004 Martin took up a postdoctoral position at UC Berkeley (USA) working in the group of Prof. Michael Marletta where he sharpened his biochemical skills. In the final year of his postdoc at Berkeley Martin applied for and was awarded the highly competitive young investigators “VENI” grant from the Netherlands Organization for Scientific Research (NWO). With this grant Martin began my career in Utrecht in 2007 as an independent junior principle investigator. As of July 1, 2018, Martin took up a new appointment as Full Professor of Biological Chemistry at the Institute of Biology Leiden (IBL). In recognition of his research accomplishments Prof. Martin has received a number of personal grants (see previous section) and in 2016 was also named as one of the top three young medicinal chemists in Europe (in voting for the EFMC Prize Young Medicinal Chemists in Academia). In addition to his research, Prof. Martin is also a dedicated teacher and was voted ‘Lecturer of the Year’ for 2015, 2016, 2017, and 2018 by the Utrecht University Molecular Life Science undergraduate students.
Professor Biological chemistry
- Science
- Instituut Biologie Leiden
- IBL Microbial Sciences
- Yakovlieva L., Wood T.M., Kemmink J., Kotsogianni Teftsoglou I., Koller F., Lassak J., Martin N.I. & Walvoort M.T.C. (2021), A β-hairpin epitope as novel structural requirement for protein arginine rhamnosylation, Chemical Science 12(4): 1560-1567.
- Haren M.J. van, Tehrani K.H.M.E., Kotsogianni Teftsoglou A.I., Wade N., Brüchle N.C., Mashayekhi V. & Martin N.I. (2021), Cephalosporin prodrug inhibitors overcome metallo‐β‐lactamase driven antibiotic resistance, Chemistry-a European Journal : 1-7.
- Diehl A., Wood T.M., Gebhard S., Martin N.I. & Fritz G. (2020), The cell envelope stress response of bacillus subtilis towards laspartomycin C, Antibiotics 9(11): 729.
- Tehrani K.H.M.E., Brüchle N.C., Wade N., Mashayekhi V., Pesce D., Haren M.J. van & Martin N.I. (2020), Small molecule carboxylates inhibit metallo-β-lactamases and resensitize carbapenem-resistant bacteria to meropenem, ACS Infectious Diseases 6(6): 1366-1371.
- Tehrani K.H.M.E., Fu H., Brüchle N.C., Mashayekhi V., Prats Luján A., Haren M.J. van, Poelarends G.J. & Martin N.I. (2020), Aminocarboxylic acids related to aspergillomarasmine A (AMA) and ethylenediamine-N,N′-disuccinic acid (EDDS) are strong zinc-binders and inhibitors of the metallo-beta-lactamase NDM-1, Chemical Communications 56(20): 3047-3049.
- Wood T.M., Bertheussen K. & Martin N.I. (2019), The contribution of achiral residues in the laspartomycin family of calcium-dependent lipopeptide antibiotics, Organic and Biomolecular Chemistry 18(3): 514-517.
- Haren M.J. van & Martin N.I. (2019), PRMT Inhibitors Topics in Medicinal Chemistry. Berlin: Springer. 1-38.
- Chiorean S., Antwi I., Carney D.W., Kotsogianni I., Giltrap A.M., Alexander F.M., Cochrane S.A., Payne R.J., Martin N.I., Henninot A. & Vederas J.C. (2020), Dissecting the Binding Interactions of Teixobactin with the Bacterial Cell‐Wall Precursor Lipid II, CHEMBIOCHEM 21(6): 789-792.
- Martin N.I. (13 September 2019), Antibiotics: the molecular marvels of modern medicine (Inaugural address. Institute of Biology (IBL), Faculty of Science, Leiden University).
- Zhang Y., Haren M.J. van & Martin N.I. (2020), Peptidic transition state analogues as PRMT inhibitors, Methods 175: 24-29.
- Gao Y., Haren M.J. van, Moret E.E., Rood J.J.M., Sartini D., Salvucci A., Emanuelli M., Craveur P., Babault N., Jin J. & Martin N.I. (2019), Bisubstrate Inhibitors of Nicotinamide N-Methyltransferase (NNMT) with Enhanced Activity, Journal of Medicinal Chemistry 62(14): 6597-6614.
- Brouwer M.S.M., Tehrani K.H.M.E., Rapallini M., Geurts Y., Kant A., Harders F., Mashayekhi V., Martin N.I., Bossers A., Mevius D.J., Wit B. & Veldman K.T. (2019), Novel Carbapenemases FLC-1 and IMI-2 Encoded by an Enterobacter cloacae Complex Isolated from Food Products, Antimicrobial Agents and Chemotherapy 63(6): e02338.
- Wood T.M. & Martin N.I. (2019), The calcium-dependent lipopeptide antibiotics: structure, mechanism, & medicinal chemistry, Medchemcomm 10(5): 634-646.
- Heesterbeek D.A.C., Martin N.I., Velthuizen A., Duijst M., Ruyken M., Wubbolts R., Rooijakker S.H.M. & Bardoel B.W. (2019), Complement-dependent outer membrane perturbation sensitizes Gram-negative bacteria to Gram-positive specific antibiotics, Scientific Reports 9: 3074.
- Lin M-H., Potel C.M., Tehrani K.H.M.E., Heck A.J.R. Martin N.I. & Lemeer S. (2018), A new tool to reveal bacterial signaling mechanisms in antibiotic treatment and resistance, Molecular and Cellular Proteomics 17(12): 2496-2507.
- Tehrani K.H.M.E. & Martin N.I. (2018), β-lactam/β-lactamase inhibitor combinations: an update, MEDCHEMCOMM 9: 1439-1456.
- Haren M.J. van, Thomas M.G., Sartini D., Barlow D.J., Ramsden D.B., Emanuelli M., Klamt F., Martin N.I. & Parsons R.B. (2018), The kinetic analysis of the N-methylation of 4-phenylpyridine by nicotinamide N-methyltransferase: Evidence for a novel mechanism of substrate inhibition, International Journal of Biochemistry and Cell Biology 98: 127-136.
- Mena-Barragán T., García-Moreno M.I., Sevšek A., Okazaki T., Nanba E., Higaki K., Martin N.I., Pieters R.J., García Fernández J.M. & Ortiz Mellet C. (2018), Probing the inhibitor versus chaperone properties of sp2-iminosugars towards human β-glucocerebrosidase: A picomolar chaperone for Gaucher disease, Molecules 23(4): 927.
- Bolt H.L., Kleijn L.H.J., Martin N.I. & Cobb S.L. (2018), Synthesis of Antibacterial Nisin–Peptoid Hybrids Using Click Methodology, Molecules 23(7): 1566.
- Brown J.I., Koopmans T., Strien J. van, Martin N.I. & Frankel A. (2018), Kinetic analysis of PRMT1 reveals multifactorial processivity and a sequential ordered mechanism, ChemBioChem 19(1): 85-99.
- Kleijn L.H.J., Vlieg H.C., Wood T.M., Sastre Toraño J., Janssen B.J.C. & Martin N.I. (2017), A High-Resolution Crystal Structure that Reveals Molecular Details of Target Recognition by the Calcium-Dependent Lipopeptide Antibiotic Laspartomycin C., Angewandte Chemie International Edition 56(52): 16546-16549.
- Bergstrom A., Katko A., Adkins Z.B., Hill J.E., Cheng Z., Burnett M.L., Yang H., Aitha M., Mehaffey M.R., Brodbelt J.S., Tehrani K.H.M.E., Martin N.I., Bonomo R.A., Page R.C., Tierney D.L., Fast W., Wright G.D. & Crowder M.W. (2018), Probing the interaction of Aspergillomarasmine A (AMA) with metallo-β-lactamases NDM-1, VIM-2, and IMP-7, ACS Infectious Diseases 4(2): 135-145.
- Hart P. ‘t, Wood T.M., Tehrani K.H.M.E., Harten R.M. van, Śleszyńska M., Rentero Rebollo I., Hendrickx A.P.A., Willems R.J.L., Breukink E. & Martin N.I. (2017), De novo identification of lipid II binding lipopeptides with antibacterial activity against vancomycin-resistant bacteria, Chemical Science 8(12): 7991-7997.
- Hajmohammadebrahimtehrani K. & Martin N.I. (2017), Thiol-Containing Metallo-β-Lactamase Inhibitors Resensitize Resistant Gram-Negative Bacteria to Meropenem, ACS Infectious Diseases 3(10): 711-717.
- Cura V., Marechal N., Troffer-Charlier N., Strub J-M., Haren M.J. van, Martin N.I., Cianferani S., Bonnefond L. & Cavarelli J. (2017), Functional insights from structural studies of protein arginine methyltransferase 2, FEBS Journal 284(1): 77-96.
- Haren M.J. van, Taig R., Kuppens J., Sastre Toraño J., Moret E.E., Parsons R.B., Sartini D., Emanuelli M. & Martin N.I. (2017), Inhibitors of nicotinamide N-methyltransferase designed to mimic the methylation reaction transition state, Organic and Biomolecular Chemistry 15(31): 6656-6667.
- Harten R.M. van, Willems R.J.L., Martin N.I. & Hendrickx A.P.A. (2017), New Compounds, Novel Antimicrobial Therapies?, Trends in Microbiology 25(6): 467-479.
- Sevšek A., Šrot L., Rihter J., Čelan M., Quarles Ufford, L. van, Moret E.E., Martin N.I. & Pieters R.J. (2017), N-Guanidino Derivatives of 1,5-Dideoxy-1,5-imino-D-xylitol are Potent, Selective, and Stable Inhibitors of β-Glucocerebrosidase, ChemMedChem 12(7): 483-486.
- Sevšek A., Sastre Toraño J., Quarles Ufford, L. van, Moret E.E., Pieters R.J. & Martin N.I. (2017), Orthoester Functionalized N-Guanidino Derivatives of 1,5-dideoxy-1,5-imino-D-xylitol as pH-Responsive Inhibitors of β-Glucocerebrosidase, MedChemComm 8(11): 2050-2054.
- Oude Blenke E., Sleszynska M., Evers M.J.W., Storm G., Martin N.I. & Mastrobattista E. (2017), Strategies for the activation and release of the membranolytic peptide melittin from liposomes using endosomal pH as a trigger, Bioconjugate Chemistry 28(2): 574-582.
- Kleijn L.H.J. & Martin N.I. (2017), The Cyclic Lipopeptide Antibiotics. In: Fisher J., Mobashery S., Miller M. (Eds.) Antibacterials. Topics in Medicinal Chemistry no. 26 Cham: Springer. 27-53.
- Haren M.J. van, Marechal N., Troffer-Charlier N., Cianciulli A., Sardella G., Cavarelli J. & Martin N.I. (2017), Transition state mimics are valuable mechanistic probes for structural studies with the arginine methyltransferase CARM1, Proceedings of the National Academy of Sciences of the United States of America 114(14): 3625-3630.
- Paige U.B.A. le, Smits B., Hart P. 't, Lefeber A.W.M., Martin N.I. & Ingen H. van (2017), Weak coupling between magnetically inequivalent spins: the deceptively simple, complicated spectrum of a C-13-labeled trimethylated amine, Journal of Magnetic Resonance 278: 96-103.
- Haren M.J. van, Sastre Toraño J., Sartini D., Emanuelli M., Parsons R.B. & Martin N.I. (2016), A rapid and efficient assay for the characterization of substrates and inhibitors of nicotinamide N-methyltransferase, Biochemistry 55(37): 5307-5315.
- Sevšek A., Čelan M., Erjavec B., Quarles Ufford L van., Sastre Toraño J., Moret E.E., Pieters R.J & Martin N.I. (2016), Bicyclic isoureas derived from 1-deoxynojirimycin are potent inhibitors of β-glucocerebrosidase, Organic and Biomolecular Chemistry 14: 8670-8673.
- Pagliero R.J., D’Astolfo D.S., Lelieveld D., Pratiwi R.D., Aits S., Jaattela M., Martin N.I., Klumperman J. & Egan D.A. (2016), Discovery of Small Molecules That Induce Lysosomal Cell Death in Cancer Cell Lines Using an Image-Based Screening Platform, ASSAY and Drug Development Technologies 14(8): 489-510.
- Oppedijk S.F., Martin N.I. & Breukink E. (2016), Hit ‘em where it hurts: the growing and structurally diverse family of peptides that target lipid-II, BBA - Biomembranes 1858(5): 947-957.
- Hart P. 't., Oppedijk S.F., Breukink E. & Martin N.I. (2016), New insights into nisin’s antibacterial mechanism revealed by binding studies with synthetic lipid II analogues, Biochemistry 55(1): 232-237.
- Thomas M.G., Sartini D., Emanuelli M., Haren, M.J. van, Martin N.I., Mountford D.M., Barlow D.J., Klamt F., Ramsden D.B., Reza M. & Parsons R.B. (2016), Nicotinamide N-methyltransferase catalyses the N-methylation of the endogenous β-carboline norharman: evidence for a novel detoxification pathway, Biochemical Journal 473(19): 3253–3267.
- Veer I.L. van 't, Leloup N.O.L., Egan A.J.F., Janssen B.J.C., Martin N.I., Vollmer W. & Breukink E. (2016), Site-specific immobilization of the peptidoglycan synthase PBP1B on a surface plasmon resonance chip surface, ChemBioChem 17(23): 2250-2256.
- Maňásková S.H., Nazmi K., Hof W. van 't, Belkum A. van, Martin N.I., Bikker F.J., Wamel W.J.B. van & Veerman E.C.I. (2016), Staphylococcus aureus Sortase A-mediated incorporation of peptides: Effect of peptide modification on incorporation, PLoS ONE 11(1): e147401.
- Kleijn L.H.J., Oppedijk S.F., Hart, P. 't, Harten R.M. van, Martin-Visscher L.A., Kemmink J., Breukink E. & Martin N.I. (2016), Total synthesis of Laspartomycin C and characterization of its antibacterial mechanism of action, Journal of Medicinal Chemistry 59(7): 3569–3574.
- Corradini E., Klaasse G., Leurs U., Heck A.J.R., Martin N.I. & Scholten A. (2015), Charting the interactome of PDE3A in human cells using an IBMX based chemical proteomics approach, Molecular Biosystems 11(10): 2786-2797.
- Oude Blenke E., Klaasse G., Merten H., Plückthun A., Mastrobattista E. & Martin N.I. (2015), Liposome functionalization with copper-free “Click Chemistry”, Journal of Controlled Release 202: 14-20.
- Gruba N., Wysocka M., Brzezińska M., Debowski D., Rolka K., Martin N.I. & Lesner A. (2015), Novel internally quenched substrate of the trypsin-like subunit of 20S eukaryotic proteasome, Analytical Biochemistry 508: 8-45.
- Koopmans T., Wood T.M., Hart, P. 't, Kleijn L.H.J., Hendrickx A.P.A., Willems R.J.L., Breukink E. & Martin N.I. (2015), Semisynthetic lipopeptides derived from nisin display antibacterial activity and lipid II-binding on par with that of the parent compound, Journal of the American Chemical Society 137(29): 9382-9389.
- Haren M.J. van, Quarles Ufford L. van, Moret E.E. & Martin N.I. (2015), Synthesis and evaluation of protein arginine N-methyltransferase inhibitors designed to simultaneously occupy both substrate binding sites, Organic and Biomolecular Chemistry 13(2): 549.
- Mooney C.A., Johnson S.A., Hart P. 't, Quarles Ufford L. van, Haan C.A.M. de, Moret E.E. & Martin N.I. (2014), Oseltamivir analogues bearing N-substituted guanidines as potent neuraminidase inhibitors, Journal of Medicinal Chemistry 57(7): 3154-3160.
- Thomas D., Koopmans T., Lakowski T.M., Kreinin H., Bui J.M., Vhuiyan M.I., Martin N.I. & Frankel A. (2014), Protein arginine N-methyltransferase substrate preferences for different N(eta)-substituted arginyl peptides, Chembiochem : a European journal of chemical biology 15(11): 1607-1613.
- Dekker F.J., Bosch T. van den & Martin N.I. (2014), Small molecule inhibitors of histone acetyltransferases and deacetylases are potential drugs for inflammatory diseases, Drug Discovery Today 19(5): 654-660.
- Mohammadi T., Sijbrandi R., Lutters M., Verheul J., Martin N.I., Blaauwen T. den, Kruijff B. de & Breukink E. (2014), Specificity of the transport of lipid II by FtsW in Escherichia coli, Journal of Biological Chemistry 289: 14707-14718.
- Hart P. 't, Kleijn L.H.J., Bruin G. de, Oppedijk S.F., Kemmink J. & Martin N.I. (2014), A combined solid- and solution-phase approach provides convenient access to analogues of the calcium-dependent lipopeptide antibiotics, Organic and Biomolecular Chemistry 12(6): 913-918.
- Koopmans T., Haren M. van, Quarles Ufford L. van, Beekman J. & Martin N.I. (2013), A concise preparation of the fluorescent amino acid L-(7-hydroxycoumarin-4-yl) ethylglycine and extension of its utility in solid phase peptide synthesis, Bioorganic and Medicinal Chemistry 21(2): 533.
- Wandelen L. van, Ameijde J. van, Ismail-Ali A., Quarles Ufford L. van, Vijftigschild L., Beekmans J., Martin N.I., Ruijtenbeek R. & Liskamp R.M.J. (2013), Cell-penetrating bisubstrate-based protein kinase C inhibitors, ACS Chemical Biology 8(7): 1479-1487.
- Hattum H. van, Martin N.I., Ruijtenbeek R. & Pieters R.J. (2013), Development of a microarray detection method for galectin cancer proteins based on ligand binding, Analytical Biochemistry 434(1): 99-104.
- Kooij R., Branderhorst H.M., Bonte S., Wieclawska S., Martin N.I. & Pieters R.J. (2013), Glycosidase inhibition by novel guanidinium and urea iminosugar derivatives, Medchemcomm 4(2): 387-393.
- Kleijn L.H.J., Müskens F.M., Oppedijk S.F., Bruin G. de & Martin N.I. (2012), A concise preparation of the non-proteinogenic amino acid L-kynurenine, Tetrahedron Letters 53(47): 6430-6432.
- Hart P. 't, Thomas D., Ommeren R. van, Lakowski T.M., Frankel A. & Martin N.I. (2012), Analogues of the HIV-Tat peptide containing Nη-modified arginines as potent inhibitors of protein arginine N-methyltransferases, Medchemcomm 3(10): 1235-1244.
- Koopmans T., Dekker F.J. & Martin N.I. (2012), A photocleavable affinity tag for the enrichment of alkyne-modified biomolecules, RSC Advances 2(6): 2244-2246.
- Olrichs N.K., Aarsman M.E.G., Verheul J., Arnusch C.J., Martin N.I., Herve M., Vollmer W., Kruijff B. de, Breukink E. & Blaauwen T.A. den (2011), A novel in vivo cell-wall labeling approach sheds new light on peptidoglycan synthesis in Escherichia coli, ChemBioChem 12(7): 1124-1133.
- Hart P. ‘t , Lakowski T.M., Thomas D., Frankel A. & Martin N.I. (2011), Peptidic partial-bisubstrates as inhibitors of the protein arginine N-methyltransferases, ChemBioChem 12(9): 1427-1432.
- Lakowski T.M., Hart P. ‘t, Ahern C.A., Martin N.I. & Frankel A. (2010), Nη-Substituted arginyl peptide inhibitors of protein arginine N-methyltransferases, ACS Chemical Biology 5(11): 1053-1063.
- Martin N.I., Woodward J.J., Winter M.B. & Marletta M.A. (2009), 4,4-Difluorinated analogues of L-arginine and NG-hydroxy-L-arginine as mechanistic probes for nitric oxide synthase, Bioorganic and Medicinal Chemistry Letters 19(6): 1758-1762.
- Martin N.I. (2009), Concise preparation of tetra-orthogonally protected (2S,6R)-lanthionines, The Journal of organic chemistry 74(2): 946-949.
- Woodward J.J., Chang M.M., Martin N.I. & Marletta M.A. (2009), The second step of the nitric oxide synthase reaction: evidence for ferric-peroxo as the active oxidant, Journal of the American Chemical Society 131(1): 297-305.
- Martin N.I., Beeson W.T., Woodward J.J. & Marletta M.A. (2008), NG-Aminoguanidines from primary amines and the preparation of nitric oxide synthase inhibitors, Journal of Medicinal Chemistry 51(4): 924-931.
- Martin N.I. & Liskamp R.M.J. (2008), Preparation of NG-substituted L-arginine analogues suitable for solid phase peptide synthesis, Journal of Organic Chemistry 40(8): 7849-7851.
- Woodward J.J., Martin N.I. & Marletta M.A. (2007), An Escherichia coli expression-based method for heme Substitution, Nature Methods 4(1): 43-45.
- Martin N.I., Woodward J.J., Winter M.B., Beeson W.T. & Marletta M.A. (2007), Design and synthesis of C5 methylated L-arginine analogues as active site probes for nitric oxide synthase, Journal of the American Chemical Society 129(41): 12563-12570.
- Pattabiraman V.R., Stymiest J.L., Derksen D.J., Martin N.I. & Vederas J.C. (2007), Multiple on-resin olefin metathesis to form ring expanded analogues of the lantibiotic peptide, lacticin 3147 A2, Organic Letters 9(4): 699-702.
- Martin N.I., Derbyshire E.R. & Marletta M.A. (2007), Synthesis and evaluation of a phosphonate analogue of the soluble guanylate cyclase activator YC-1, Bioorganic and Medicinal Chemistry Letters 17(17): 4938-4941.
- Martin N.I. & Breukink E. (2007), The expanding role of lipid II as a target for lantibiotics, Future Microbiology 2(5).
- Martin N.I., Woodward J.J. & Marletta M.A. (2006), NG-Hydroxyguanidines from primary amines, Organic Letters 8(18): 4035-4038.
- Gursky L.J., Martin N.I., Derksen D.J., Belkum M.J. van, Kaur K., Vederas J.C., Stiles M.E. & McMullen L.M. (2006), Production of piscicolin 126 by Carnobacterium maltaromaticum UAL26 is controlled by temperature and induction peptide concentration, Archives of Microbiology 186: 317-325.
- Martin N.I., Hu H., Moake M.M., Churey J.J., Whittal R., Worobo R.W. & Vederas J.C. (2003), Isolation, structural characterization and properties of mattacin (polymyxin M), a cyclic peptide antibiotic produced by Paenibacillus kobensis M, Journal of Biological Chemistry 278: 13124-13132.
- Ramtohul Y.K., Martin N.I., Silkin L., James M.N.H. & Vederas J.C. (2002), Synthesis of pseudoxazolones and their inhibition of the 3C cysteine proteinases from hepatitis A virus and human rhinovirus-14, Journal of the Chemical Society Perkin Transactions 1 1(11): 1351-1359.
- Garneau S., Martin N.I. & Vederas J.C. (2002), Two-peptide bacteriocins produced by lactic acid bacteria, Biochimie 84(5-6): 577-592.
- Ramtohul Y.K., Martin N.I., Silkin L., James M.N.G. & Vederas J.C. (2001), Pseudoxazolones, a new class of inhibitors for cysteine proteinases: Inhibition of hepatitis A virus and human rhinovirus 3C proteinases, Chemical Communications 2001(24): 2740-2741.
- Mahaffy P.G., Martin N.I., Newman K.E., Hohn B., Mikula R.J. & Munoz V.A. (1998), Laundry Dryer Lint: A novel matrix for non-intrusive environmental lead screening, Environmental Science & Technology 32(16): 2467-2473.
- co-founder
- ad hoc referee for numerous scientific journals