Medical Systems Biophysics and Bioengineering
Key publications
Key publications of the Medical Systems Biophysics and Bioengineeringgroup (Mashaghi Lab)
- Mashaghi A., Kramer G., Bechtluft P., Zachmann-Brand B., Driessen A.J., Bukau B., and Tans S.J., Reshaping of the conformational search of a protein by the chaperone trigger factor. Nature 500(7460): 98-101 (2013)
- van Wijk R., Tans S., ten Wolde P.R., Mashaghi A., Non-monotonic dynamics and crosstalk in signaling pathways and their implications for pharmacology, Scientific Reports 5, 11376 (2015)
- Ungelenk S., Moayed F., Scharf A., Mashaghi A., Tans S.J., Mayer M.P., Mogk A., Bukau B., Small heat shock proteins hold stress-aggregated proteins in near-native conformation for efficient refolding, 7: 13673 Nature Communications (2016)
- Mashaghi A., Bezrukavnikov S., Minde D.P., Wentink A.S., Kityk R., Zachmann-Brand B., Mayer M.P., Kramer G., Bukau B., and Tans S.J., Alternative modes of client binding enable functional plasticity of Hsp70. Nature 539(7629): 448-451 (2016)
- Ghafari M. and Mashaghi A., On the role of topology in regulating transcriptional cascades. Physical Chemistry Chemical Physics 19, 25168-25179 (2017)
- Eslani M., Putra I., Shen X., Hamouie J., Tadepalli A., Anwar K.N., Kink J.A., Ghassemi S., Agnihotri G., Reshetylo S., Mashaghi A., Dana R., Hematti P., Djalilian A.R., Cornea Derived MSCs Therapeutically modulate macrophage immunophenotype and angiogenic function. Stem Cells (2018)
- Ramezanpour A., Beam A.L., Chen J.H., Mashaghi A. Statistical Physics for Medical Diagnostics: Learning, Inference, and Optimization Algorithms. Diagnostics 10(11):972 (2020)
- Heidari M. Schiessel H. Mashaghi A. (2020), Circuit Topology Analysis of Polymer Folding Reactions, ACS Central Science 6(6): 839-847.
- Junaid A.O., Tang H., Reeuwijk A. van, Abouleila Y.A.M.I., Wuelfroth P., Duinen V. van, Stam W., Zonneveld A.J. van, Hankemeier T. & Mashaghi Tabari A. (2020), Ebola Hemorrhagic Shock Syndrome-on-a-Chip, iScience 23(1): 100765.
- Evers T., Holt L., Alberti S., Mashaghi A. Reciprocal regulation of cellular mechanics and metabolism. Nature Metabolism 3, 456-468 (2021)
- Scalvini B., Schiessel H., Golonev A. & Mashaghi Tabari A. (2022), Circuit topology analysis of cellular genome reveals signature motifs, conformational heterogeneity, and scaling, iScience 25(3): 103866.
- Scalvini B., Heling L.W.H.J., Sheikhhassani V., Sunderlikova V., Tans S.J. & Mashaghi Tabari A. (2023), Cytosolic interactome protects against protein unfolding in a single molecule experiment, Advanced Biology 7(12): 2300105.