Macromolecular Biochemistry

Macromolecular Biochemistry is a section of the Leiden Institute of Chemistry at Leiden University, comprising the PIs Marcellus Ubbink, Remus Dame, Aimee Boyle and Lars Jeuken.

The research is aimed at understanding peptide, protein & nucleic acid structure, function and interactions. Particular interests comprise protein-protein interactions & enzyme function (Prof. Ubbink), biophysical aspects of protein - DNA interactions (Prof. Dame), and peptide/protein-metal interactions, applications of designed metallo-peptides and proteins (Dr. Boyle) and protein - nanoparticle interactions for applicationd in light-driven redox catalysis (Prof. Jeuken).

The section houses equipment for recombinant protein production and a variety biophysical characterisation methods.