Universiteit Leiden

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Drug research

In the Drug Research theme, we primarily work with rodents. Rodents, such as mice, are one of the most common laboratory animals. These small mammals are easily housed and exhibit a rapid rate of reproduction.

Mice as models for human diseases

In drug research, we employ advanced laboratory animal models that serve as representations for the diseases we aim to comprehend and treat. Frequently, we use so-called humanised mouse models for this type of research. Through genetic modifications of these animals, we can investigate the progression of diseases such as cancer, atherosclerosis or neurological complications. The insights gained from studies using these mouse models contribute to the ongoing development of new drugs for human use.

Fundamental insights for new medications

Conducting fundamental research with these mouse models enables us to enhance our understanding of the biological processes at a cellular level that form the basis of diseases. These type of animal experiments aid in identifying drug targets for the development of new medicines.

Testing the safety of new medications

These mouse models are also used for the final stage in developmental drug research. In this stage, candidate drugs must be tested on laboratory animals to ensure that subsequent human trials are conducted as safe as possible.

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