Universiteit Leiden

nl en

Proefschrift

Through the magnifying glass

Although nanoparticles are extensively used in various applications like consumer products and have most probably entered the environment, little is known about the effects of these particles on living organisms.

Auteur
Pomeren, M. van
Datum
17 april 2019
Links
Thesis in Leiden Repository

Although nanoparticles are extensively used in various applications like consumer products and have most probably entered the environment, little is known about the effects of these particles on living organisms. In this thesis, we aim to understand how the size and shape of nanoparticles influence their toxicity. Not only do we compare the toxic effect of these material characteristics over a series of metallic nanoparticles, therewith eliminating the effect of the core-material, but do we also investigate on an individual level where the particles migrate to inside the organism. This thesis aims to obtain a better understanding of the uptake, biodistribution and subsequent toxicity of nanoparticles, moving forward from the “organism as a black box” principle to a more detailed understanding of the harm caused by nanoparticles.

Deze website maakt gebruik van cookies. Meer informatie