Rolf Vossen
- Naam
- Ing. R.H.A.M. Vossen
- Telefoon
- +31 71 526 9111
- r.vossen@lumc.nl
- Faculteit Geneeskunde
- Divisie 4
- Humane Genetica
- Ducarmon, Q.R.; Bruggen, T. van der; Harmanus, C.; Sanders, I.M.J.G.; Daenen, L.G.M.; Fluit, A.C.; Vossen, R.H.A.M.; Kloet, S.L.; Kuijper, E.J. & Smits, W.K. (2023), Clostridioides difficile infection with isolates of cryptic clade C-II: a genomic analysis of polymerase chain reaction ribotype 151, Clinical Microbiology and Infection 29(4): 538e1-538e6.
- Roseboom, A.M.; Ducarmon, Q.R.; Hornung, B.V.H.; Harmanus, C.; Crobach, M.J.T.; Kuijper, E.J.; Vossen, R.H.A.M.; Kloet, S.L. & Smits, W.K. (2023), Carriage of three plasmids in a single human clinical isolate of Clostridioides difficile, Plasmid 125.
- Kampfraath, A.A.; Klasson, L.; Anvar, S.Y.; Vossen, R.H.A.M.; Roelofs, D.; Kraaijeveld, K. & Ellers, J. (2019), Genome expansion of an obligate parthenogenesis-associated Wolbachia poses an exception to the symbiont reduction model, BMC Genomics 20.
- Weerts, M.J.A.; Timmermans, E.C.; Stolpe, A. van de; Vossen, R.H.A.M.; Anvar, S.Y.; Foekens, J.A.; Sleijfer, S. & Martens, J.W.M. (2018), Tumor-Specific Mitochondrial DNA Variants Are Rarely Detected in Cell-Free DNA, Neoplasia 20(7): 687-696.
- Prokopuk, L.; Stringer, J.M.; White, C.R.; Vossen, R.H.A.M.; White, S.J.; Cohen, A.S.A.; Gibson, W.T. & Western, P.S. (2018), Loss of maternal EED results in postnatal overgrowth, Clinical Epigenetics 10.
- Frank, J.; Lucker, S.; Vossen, R.H.A.M.; Jetten, M.S.M.; Hall, R.J.; Camp, H.J.M.O. den & Anvar, S.Y. (2018), Resolving the complete genome of Kuenenia stuttgartiensis from a membrane bioreactor enrichment using Single-Molecule Real-Time sequencing, Scientific Reports 8.
- Schubert, S.A.; Ruano, D.; Elsayed, F.A.; Boot, A.; Crobach, S.; Sarasqueta, A.F.; Wolffenbuttel, B.; Klauw, M.M. van der; Oosting, J.; Tops, C.M.; Eijk, R. van; Vasen, H.F.A.; Vossen, R.H.A.M.; Nielsen, M.; Castellvi-Bel, S.; Ruiz-Ponte, C.; Tomlinson, I.; Dunlop, M.G.; Vodicka, P.; Wijnen, J.T.; Hes, F.J.; Morreau, H.; Miranda, N.F.C.C. de; Sijmons, R.H. & Wezel, T. van (2017), Evidence for genetic association between chromosome 1q loci and predisposition to colorectal neoplasia, British Journal of Cancer 117(8): 1215-1223.
- Borras, D.M.; Vossen, R.H.A.M.; Liem, M.; Buermans, H.P.J.; Dauwerse, H.; Heusden, D. van; Gansevoort, R.T.; Dunnen, J.T. den; Janssen, B.; Peters, D.J.M.; Losekoot, M. & Anvar, S.Y. (2017), Detecting PKD1 variants in polycystic kidney disease patients by single-molecule long-read sequencing, Human Mutation 38(7): 870-879.
- Buermans, H.P.J.; Vossen, R.H.A.M.; Anvar, S.Y.; Allard, W.G.; Guchelaar, H.J.; White, S.J.; Dunnen, J.T. den; Swen, J.J. & Straaten, T. van der (2017), Flexible and Scalable Full-Length CYP2D6 Long Amplicon PacBio Sequencing, Human Mutation 38(3): 310-316.
- Frank, J.; Dingemanse, C.; Schmitz, A.M.; Vossen, R.H.A.M.; Ommen, G.J.B. van; Dunnen, J.T. den; Robanus-Maandag, E.C. & Anvar, S.Y. (2016), The Complete Genome Sequence of the Murine Pathobiont Helicobacter typhlonius, Frontiers in Microbiology 6.
- Hassan, S.M.; Vossen, R.H.A.M.; Chessa, R.; Dunnen, J.T. den; Bakker, E.; Giordano, P. & Harteveld, C.L. (2014), Molecular diagnostics of the HBB gene in an Omani cohort using bench-top DNA Ion Torrent PGM technology, Blood Cells, Molecules and Diseases 53(3): 133-137.
- Anvar, S.Y.; Gaag, K.J. van der; Heijden, J.W.F. van der; Veltrop, M.H.A.M.; Vossen, R.H.A.M.; Leeuw, R.H. de; Breukel, C.; Buermans, H.P.J.; Verbeek, J.S.; Knijff, P. de; Dunnen, J.T. den & Laros, J.F.J. (2014), TSSV: a tool for characterization of complex allelic variants in pure and mixed genomes, Bioinformatics 30(12): 1651-1659.
- Passtoors, W.M.; Boer, J.M.; Goeman, J.J.; Akker, E.B. van den; Deelen, J.; Zwaan, B.J.; Scarborough, A.; Breggen, R. van der; Vossen, R.H.A.M.; Houwing-Duistermaat, J.J.; Ommen, G.J.B. van; Westendorp, R.G.J.; Heemst, D. van; Craen, A.J.M. de; White, A.J.; Gunn, D.A.; Beekman, M. & Slagboom, P.E. (2012), Transcriptional Profiling of Human Familial Longevity Indicates a Role for ASF1A and IL7R, PLoS ONE 7(1): -.
- Aten, E.; Brasz, L.C.; Bornholdt, D.; Hooijkaas, I.B.; Porteous, M.E.; Sybert, V.P.; Vermeer, M.H.; Vossen, R.H.A.M.; Wielen, M.J.R. van der; Bakker, E.; Breuning, M.H.; Grzeschik, K.H.; Oosterwijk, J.C. & Dunnen, J.T. den (2010), Keratosis Follicularis Spinulosa Decalvans Is Caused by Mutations in MBTPS2, Human Mutation 31(10): 1125-1133.
- Spitali, P.; Heemskerk, H.; Vossen, R.H.A.M.; Ferlini, A.; Dunnen, J.T. den; Hoen, P.A.C. 't & Aartsma-Rus, A. (2010), Accurate quantification of dystrophin mRNA and exon skipping levels in Duchenne Muscular Dystrophy, Laboratory Investigation 90(9): 1396-1402.
- Vossen, R.H.A.M.; Duijn, M. van; Daha, M.R.; Dunnen, J.T. den & Roos, A. (2010), High-throughput Genotyping of Mannose-binding Lectin Variants Using High-resolution DNA-melting Analysis, Human Mutation 31(4): E1286E1293.
- Pepers BA, Schut MH, Vossen RH, van Ommen GJ, den Dunnen JT & van Roon-Mom WM (2009), Cost-effective HRMA pre-sequence typing of clone libraries; application to phage display selection., BMC Biotechnology 9: 50.
- Filipe B, Albuquerque C, Bik E, Lage P, Rodrigues P, Vossen R, Tops C & Leitao CN (2009), APC Somatic Mosaicism in a Patient with Gardner Syndrome Carrying the E1573X Mutation: Report of a Case, Diseases of the Colon and Rectum 52(8): 1516-1520.
- Vossen, R.H.A.M.; Aten, E.; Roos, A. & Dunnen, J.T. den (2009), High-resolution melting analysis (HRMA): more than just sequence variant screening., Human Mutation: Variation, Informatics and Disease 30(6): 860-6.
- t Hoen PAC, Ariyurek Y, Thygesen HH, Vreugdenhil E, Vossen RHAM, de Menezes RX, Boer JM, van Ommen GJB & den Dunnen JT (2008), Deep sequencing-based expression analysis shows major advances in robustness, resolution and inter-lab portability over five microarray platforms, Nucleic Acids Research 36(21).
- Pedotti P, t Hoen PA, Vreugdenhil E, Schenk GJ, Vossen RH, Ariyurek Y, de Hollander M, Kuiper R, van Ommen GJB, den Dunnen JT, Boer JM & de Menezes RX (2008), Can subtle changes in gene expression be consistently detected with different microarray platforms?, BMC Genomics 9.
- 't Hoen PAC, de Meijer EJ, Boer JM, Vossen RHAM, Turk R, Maatman RGHJ, Davies KE, van Ommen GJB, van Deutekom JCT & den Dunnen JT (2008), Generation and characterization of transgenic mice with the full-length human DMD gene, Journal of Biological Chemistry 283(9).
- Boon EMJ, Schleeht HB, Martin P, Daniels G, Vossen RHAM, Den Dunnen JT, Bakker B & Elles R (2007), Y chromosome detection by Real Time PCR and pyrophosphorolysis-activated DNA isolated from maternal polymerisation using free fetal plasma, Prenatal Diagnosis 27(10).
- Roos A, Dieltjes P, Vossen RHAM, Daha MR & de Knijff P (2006), Detection of three single nucleotide polymorphisms in the gene encoding mannose-binding lectin in a single pyrosequencing reaction, Journal of Immunological Methods 309(1-2).
- Lalic T, Vossen RH, Coffa J, Schouten JP, Guc-Scekic M, Radivojevic D, Djurisic M, Breuning MH, White SJ & den Dunnen JT (2005), Deletion and duplication screening in the DMD gene using MLPA, European Journal of Human Genetics 13(11).
- Bremmer-Bout M, Aartsma-Rus A, de Meijer EJ, Kaman WE, Janson AAM, Vossen RHAM, van Ommen GJB, den Dunnen JT & van Deutekom JCT (2004), Targeted exon skipping in transgenic hDMD mice: A model for direct preclinical screening of human-specific antisense oligonucleotides, Molecular Therapy 10(2).
- Hofstra RMW, Mulder IM, Vossen R, de Koning-Gans PAM, Kraak M, Ginjaar IB, van der Hout AH, Bakker E, Buys CHCM, van Ommen GJB, van Essen AJ & den Dunnen JT (2004), DGGE based whole-gene mutation scanning of the dystrophlin gene in Duchenne and Becker muscular dystrophy patients, Human Mutation 23(1).
- Berns EMJJ, Klijn JGM, Look MP, Grebenchtchikov N, Vossen R, Peters H, Geurts-Moespot A, Portengen H, van Staveren IL, Meijer-van Gelder ME, Bakker B, Sweep FCGJ & Foekens JA (2003), Combined vascular endothelial growth factor and TP53 status predicts poor response to tamoxifen therapy in estrogen receptor-positive advanced breast cancer, Clinical Cancer Research 9(4).
- Berns EMJJ, Foekens JA, Vossen R, Look MP, Devilee P, Henzen-Logmans SC, van Staveren IL, van Putten WLJ, Inganas M, Meijer-van Gelder ME, Cornelisse C, Claassen CJC, Portengen H, Bakker B & Klijn JGM (2000), Complete sequencing of TP53 predicts poor response to systemic therapy of advanced breast cancer.