Lizi Xia
Promovendus / gast
- Naam
- Dr. L. Xia
- Telefoon
- +31 71 527 4237
- l.xia.2@lacdr.leidenuniv.nl
Promovendus / gast
- Wiskunde en Natuurwetenschappen
- Leiden Academic Centre for Drug Research
- LACDR/Medicinal Chemistry
- Bouma J., Soethoudt M., Gils N. van, Xia L., Stelt M van der & Heitman L.H. (2022), Cellular assay to study β-arrestin recruitment by the cannabinoid receptors 1 and 2. In: Maccarrone M. (red.), Endocannabinoid Signaling. Methods in Molecular Biology nr. 2576. New York, U.S.A.: Humana. 189-199.
- Xia L. (30 mei 2018), Corpora non agunt nisi fixata : ligand receptor binding kinetics in G protein-coupled receptors (Dissertatie. Leiden Academic Centre for Drug Research (LACDR), Science, Leiden University). Promotor(en) en copromotor(en): IJzerman A.P., Heitman L.H.
- Xia L., Vries H. de, Yang X., Lenselink E.B., Kyrizaki A., Barth F., Louvel J., Dreyer M.K., Es D. van der, IJzerman A.P. & Heitman L.H. (2018), Kinetics of human cannabinoid 1 (CB1) receptor antagonists: Structure-kinetics relationships (SKR) and implications for insurmountable antagonism, Biochemical Pharmacology 151: 166-179.
- Xia L.Z., Kyrizaki A., Tosh D.K., Duijl T.T. van, Roorda J.C., Jacobson K.A., IJzerman A.P. & Heitman L.H. (2018), A binding kinetics study of human adenosine A(3) receptor agonists, Biochemical Pharmacology 153: 248-259.
- Xia L., Vries H. de, Lenselink E.B., Louvel J.A., Waring M.J., Cheng L., Pahlen S., Petersson M.J., Schell P., Olsson R.I., Heitman L.H., Sheppard R.J. & IJzerman A.P. (2017), Structure-Affinity Relationships and Structure-Kinetic Relationships of 1,2-Diarylimidazol-4-carboxamide Derivatives as Human Cannabinoid 1 Receptor Antagonists, Journal of Medicinal Chemistry 60(23): 9545-9564.
- Xia L., Burger W.A.C., Veldhoven J.P.D. van, Kuiper B.J., Duijl T.T. van, Lenselink E.B., Paasman E., Heitman L.H. & IJzerman A.P. (2017), Structure-Affinity Relationships and Structure-Kinetics Relationships of Pyrido[2,1-f]purine-2,4-dione Derivatives as Human Adenosine A(3) Receptor Antagonists, Journal of Medicinal Chemistry 60(17): 7555-7568.
- Xia L., Vries H. de, IJzerman A.P. & Heitman L.H. (2016), Scintillation proximity assay (SPA) as a new approach to determine a ligand's kinetic profile. A case in point for the adenosine A1 receptor, Purinergic Signalling 12(1): 115-126.
- Massink A., Gutiérrez-de-Terán H., Lenselink E.B., Ortiz Zacarías N.V., Xia L., Heitman L.H., Katritch V., Stevens R.C. & IJzerman A.P. (2015), Sodium Ion Binding Pocket Mutations and Adenosine A2A Receptor Function, Molecular Pharmacology 87(2): 305-13.
- Guo D., Xia L., Veldhoven J.P.D. van, Hazeu M.D., Mocking T., Brussee J.M., IJzerman A.P. & Heitman L.H. (2014), Binding kinetics of ZM241385 derivatives at the human adenosine A(2A) receptor, ChemMedChem 9(4): 752-761.
- Louvel J.A., Guo D., Agliardi M., Mocking T.A.M., Kars R., Xia L., Vries H. de, Brussee J., Heitman L.H. & IJzerman A.P. (2014), Agonists for the adenosine A(1) receptor with tunable residence time: a case for nonribose 4-Amino-6-aryl-5-cyano-2-thiopyrimidines, Journal of Medicinal Chemistry 57(8): 3213-3222.
Geen relevante nevenwerkzaamheden