Jeanine Houwing-Duistermaat
Hoogleraar
- Naam
- Prof. dr. J.J. Houwing-Duistermaat
- Telefoon
- 071 5269707
- j.j.houwing@lumc.nl
- ORCID iD
- 0000-0002-4505-7137
Hoogleraar
- Faculteit Geneeskunde
- LUMC
- Fuady, A.M.; Roon-Mom, W.M.C. van; Kielbasa, S.M.; Uh, H.W. & Houwing-Duistermaat, J.J. (2020), Statistical method for modeling sequencing data from different technologies in longitudinal studies with application to Huntington disease, Biometrical Journal 63(4).
- Esquivel-Muelbert, A.; Phillips, O.L.; Brienen, R.J.W.; Fauset, S.; Sullivan, M.J.P.; Baker, T.R.; Chao, K.J.; Feldpausch, T.R.; Gloor, E.; Higuchi, N.; Houwing-Duistermaat, J.; Lloyd, J.; Liu, H.Y.; Malhi, Y.; Marimon, B.; Marimon, B.; Monteagudo-Mendoza, A.; Poorter, L.; Silveira, M.; Torre, E.V.; Davila, E.A.; Pasquel, J.D.; Almeida, E.; Loayza, P.A.; Andrade, A.; Aragao, L.E.O.C.; Araujo-Murakami, A.; Arets, E.; Arroyo, L.; Aymard, G.A.; Baisie, M.; Baraloto, C.; Camargo, P.B.; Barroso, J.; Blanc, L.; Bonal, D.; Bongers, F.; Boot, R.; Brown, F.; Burban, B.; Camargo, J.L.; Castro, W.; Moscoso, V.C.; Chave, J.; Comiskey, J.; Valverde, F.C.; Costa, A.L. da; Cardozo, N.D.; Fiore, A. di; Dourdain, A.; Erwin, T.; Llampazo, G.F.; Vieira, I.C.G.; Herrera, R.; Honorio Coronado, E.; Huamantupa-Chuquimaco, I.; Jimenez-Rojas, E.; Killeen, T.; Laurance, S.; Laurance, W.; Levesley, A.; Lewis, S.L.; Ladvocat, K.L.L.M.; Lopez-Gonzalez, G.; Lovejoy, T.; Meir, P.; Mendoza, C.; Morandi, P.; Neill, D.; Nogueira Lima, A.J.; Vargas, P.N.; Oliveira, E.A. de; Camacho, N.P.; Pardo, G.; Peacock, J.; Pena-Claros, M.; Penuela-Mora, M.C.; Pickavance, G.; Pipoly, J.; Pitman, N.; Prieto, A.; Pugh, T.A.M.; Quesada, C.; Ramirez-Angulo, H.; Almeida Reis, S.M. de; Rejou-Machain, M.; Correa, Z.R.; Bayona, L.R.; Rudas, A.; Salomao, R.; Serrano, J.; Espejo, J.S.; Silva, N.; Singh, J.; Stahl, C.; Stropp, J.; Swamy, V.; Talbot, J.; Steege, H. ter; Terborgh, J.; Thomas, R.; Toledo, M.; Torres-Lezama, A.; Gamarra, L.V.; Heijden, G. van der; Meer, P. van der; Hout, P. van der; Martinez, R.V.; Vieira, S.A.; Cayo, J.V.; Vos, V.; Zagt, R.; Zuidema, P. & Galbraith, D. (2020), Tree mode of death and mortality risk factors across Amazon forests, Nature Communications 11(1).
- Raymond, B.; Bouwman, A.C.; Schrooten, C.; Houwing-Duistermaat, J. & Veerkamp, R.F. (2018), Utility of whole-genome sequence data for across-breed genomic prediction, Genetics Selection Evolution 50.
- Bas-Hoogendam, J.M.; Harrewijn, A.; Tissier, R.L.M.; Molen, M.J.W. van der; Steenbergen, H. van; Vliet, I.M. van; Reichart, C.G.; Houwing-Duistermaat, J.J.; Slagboom, P.E.; Wee, N.J.A. van der & Westenberg, P.M. (2018), The Leiden Family Lab study on Social Anxiety Disorder: A multiplex, multigenerational family study on neurocognitive endophenotypes, International Journal of Methods in Psychiatric Research 27(2).
- Rodriguez-Girondo, M.; Deelen, J.; Slagboom, E.P. & Houwing-Duistermaat, J.J. (2018), Survival analysis with delayed entry in selected families with application to human longevity, Statistical Methods in Medical Research 27(3): 933-954.
- Bas-Hoogendam, J.M.; Steenbergen, H. van; Tissier, R.L.M.; Houwing-Duistermaat, J.J.; Westenberg, P.M. & Wee, N.J.A. van der (2018), Subcortical brain volumes, cortical thickness and cortical surface area in families genetically enriched for social anxiety disorder - A multiplex multigenerational neuroimaging study, EBioMedicine 36: 410-428.
- Rodriguez-Girondo, M.; Salo, P.; Burzykowski, T.; Perola, M.; Houwing-Duistermaat, J. & Mertens, B. (2018), SEQUENTIAL DOUBLE CROSS-VALIDATION FOR ASSESSMENT OF ADDED PREDICTIVE ABILITY IN HIGH-DIMENSIONAL OMIC APPLICATIONS, Annals of Applied Statistics 12(3): 1655-1678.
- Bouhaddani, S. el; Uh, H.W.; Hayward, C.; Jongbloed, G. & Houwing-Duistermaat, J. (2018), Probabilistic partial least squares model: Identifiability, estimation and application, Journal of Multivariate Analysis 167: 331-346.
- Berg, N. van den; Rodriguez-Girondo, M.; Craen, A.J.M. de; Houwing-Duistermaat, J.J.; Beekman, M. & Slagboom, P.E. (2018), Longevity Around the Turn of the 20th Century: Life-Long Sustained Survival Advantage for Parents of Today's Nonagenarians, Journals of Gerontology, Series A 73(10): 1295-1302.
- Bouhaddani, S. el; Uh, H.W.; Jongbloed, G.; Hayward, C.; Klaric, L.; Kielbasa, S.M. & Houwing-Duistermaat, J. (2018), Integrating omics datasets with the OmicsPLS package, BMC Bioinformatics 19.
- Tissier, R.; Houwing-Duistermaat, J. & Rodriguez-Girondo, M. (2018), Improving stability of prediction models based on correlated omics data by using network approaches, PLoS ONE 13(2).
- Harrewijn, A.; Molen, M.J.W. van der; Verkuil, B.; Sweijen, S.W.; Houwing-Duistermaat, J.J. & Westenberg, P.M. (2018), Heart rate variability as candidate endophenotype of social anxiety: A two-generation family study, Journal of Affective Disorders 237: 47-55.
- Raymond, B.; Bouwman, A.C.; Wientjes, Y.C.J.; Schrooten, C.; Houwing-Duistermaat, J. & Veerkamp, R.F. (2018), Genomic prediction for numerically small breeds, using models with pre-selected and differentially weighted markers, Genetics Selection Evolution 50.
- Martin, I.; Djuardi, Y.; Sartono, E.; Rosa, B.A.; Supali, T.; Mitreva, M.; Houwing-Duistermaat, J.J. & Yazdanbakhsh, M. (2018), Dynamic changes in human-gut microbiome in relation to a placebo-controlled anthelminthic trial in Indonesia, PLoS Neglected Tropical Diseases 12(8).
- Harrewijn, A.; Molen, M.J.W. van der; Vliet, I.M. van; Houwing-Duistermaat, J.J. & Westenberg, P.M. (2018), Delta-beta correlation as a candidate endophenotype of social anxiety: A two-generation family study, Journal of Affective Disorders 227: 398-405.
- Ruiter, K. de; Tahapary, D.L.; Wammes, L.J.; Wiria, A.E.; Hamid, F.; Lieshout, L. van; Smit, J.W.A.; Houwing-Duistermaat, J.J.; Sartono, E.; Supali, T. & Yazdanbakhsh, M. (2017), The effect of three-monthly albendazole treatment on Th2 responses: Differential effects on IgE and IL-5, Parasite Immunology 39(6).
- Plomp, R.; Ruhaak, L.R.; Uh, H.W.; Reiding, K.R.; Selman, M.; Houwing-Duistermaat, J.J.; Slagboom, P.E.; Beekman, M. & Wuhrer, M. (2017), Subclass-specific IgG glycosylation is associated with markers of inflammation and metabolic health, Scientific Reports 7.
- Ben-Avraham, D.; Karasik, D.; Verghese, J.; Lunetta, K.L.; Smith, J.A.; Eicher, J.D.; Vered, R.; Deelen, J.; Arnold, A.M.; Buchman, A.S.; Tanaka, T.; Faul, J.D.; Nethander, M.; Fornage, M.; Adams, H.H.; Matteini, A.M.; Callisaya, M.L.; Smith, A.V.; Yu, L.; Jager, P.L. de; Evans, D.A.; Gudnason, V.; Hofman, A.; Pattie, A.; Corley, J.; Launer, L.J.; Knopman, D.S.; Parimi, N.; Turner, S.T.; Bandinelli, S.; Beekman, M.; Gutman, D.; Sharvit, L.; Mooijaart, S.P.; Liewald, D.C.; Houwing-Duistermaat, J.J.; Ohlsson, C.; Moed, M.; Verlinden, V.J.; Mellstrom, D.; Geest, J.N. van der; Karlsson, M.; Hernandez, D.; McWhirter, R.; Liu, Y.M.; Thomson, R.; Tranah, G.J.; Uitterlinden, A.G.; Weir, D.R.; Zhao, W.; Starr, J.M.; Johnson, A.D.; Ikram, M.A.; Bennett, D.A.; Cummings, S.R.; Deary, I.J.; Harris, T.B.; Kardia, S.L.R.; Mosley, T.H.; Srikanth, V.K.; Windham, B.G.; Newman, A.B.; Walston, J.D.; Davies, G.; Evans, D.S.; Slagboom, E.P.; Ferrucci, L.; Kiel, D.P.; Murabito, J.M. & Atzmon, G. (2017), The complex genetics of gait speed: genome-wide meta-analysis approach (vol 9, pg 209, 2017), Aging 9(7): 1844-1846.
- Ben-Avraham, D.; Karasik, D.; Verghese, J.; Lunetta, K.L.; Smith, J.A.; Eicher, J.D.; Vered, R.; Deelen, J.; Arnold, A.M.; Buchman, A.S.; Tanaka, T.; Faul, J.D.; Nethander, M.; Fornage, M.; Adams, H.H.; Matteini, A.M.; Callisaya, M.L.; Smith, A.V.; Yu, L.; Jager, P.L. de; Evans, D.A.; Gudnason, V.; Hofman, A.; Pattie, A.; Corley, J.; Launer, L.J.; Knopman, D.S.; Parimi, N.; Turner, S.T.; Bandinelli, S.; Beekman, M.; Gutman, D.; Sharvit, L.; Mooijaart, S.P.; Liewald, D.C.; Houwing-Duistermaat, J.J.; Ohlsson, C.; Moed, M.; Verlinden, V.J.; Mellstrom, D.; Geest, J.N. van der; Karlsson, M.; Hernandez, D.; McWhirter, R.; Liu, Y.M.; Thomson, R.; Tranah, G.J.; Uitterlinden, A.G.; Weir, D.R.; Zhao, W.; Starr, J.M.; Johnson, A.D.; Ikram, M.A.; Bennett, D.A.; Cummings, S.R.; Deary, I.J.; Harris, T.B.; Kardia, S.L.R.; Mosley, T.H.; Srikanth, V.K.; Windham, B.G.; Newman, A.B.; Walston, J.D.; Davies, G.; Evans, D.S.; Slagboom, E.P.; Ferrucci, L.; Kiel, D.P.; Murabito, J.M. & Atzmon, G. (2017), The complex genetics of gait speed: genome-wide meta-analysis approach, Aging 9(1): 209-246.
- Xu, M.K.; Gaysina, D.; Tsonaka, R.; Morin, A.J.S.; Croudace, T.J.; Barnett, J.H.; Houwing-Duistermaat, J.; Richards, M.; Jones, P.B. & LHA Genetics Grp (2017), Monoamine Oxidase A (MAOA) Gene and Personality Traits from Late Adolescence through Early Adulthood: A Latent Variable Investigation, Frontiers in Psychology 8.
- Reiding, K.R.; Ruhaak, L.R.; Uh, H.W.; Bouhaddani, S. el; Akker, E.B. van den; Plomp, R.; McDonnell, L.A.; Houwing-Duistermaat, J.J.; Slagboom, P.E.; Beekman, M. & Wuhrer, M. (2017), Human Plasma N-glycosylation as Analyzed by Matrix-Assisted Laser Desorption/Ionization-Fourier Transform Ion Cyclotron Resonance-MS Associates with Markers of Inflammation and Metabolic Health, Molecular and Cellular Proteomics 16(2): 228-242.
- Bartzis, G.; Deelen, J.; Maia, J.; Ligterink, W.; Hilhorst, H.W.M.; Houwing-Duistermaat, J.J.; Eeuwijk, F. van & Uh, H.W. (2017), Estimation of metabolite networks with regard to a specific covariable: applications to plant and human data.
- Tahapary, D.L.; Ruiter, K. de; Martin, I.; Brienen, E.A.T.; Lieshout, L. van; Djuardi, Y.; Djimandjaja, C.C.; Houwing-Duistermaat, J.J.; Soewondo, P.; Sartono, E.; Supali, T.; Smit, J.W.A. & Yazdanbakhsh, M. (2017), Effect of anthelmintic treatment on leptin, adiponectin and leptin to adiponectin ratio: a randomized-controlled trial, Nutrition and Diabetes 7.
- Tahapary, D.L.; Ruiter, K. de; Martin, I.; Brienen, E.A.T.; Lieshout, L. van; Cobbaert, C.M.; Soewondo, P.; Djuardi, Y.; Wiria, A.E.; Houwing-Duistermaat, J.J.; Sartono, E.; Smit, J.W.A.; Yazdanbakhsh, M. & Supali, T. (2017), Effect of Anthelmintic Treatment on Insulin Resistance: A Cluster-Randomized, Placebo-Controlled Trial in Indonesia, Clinical Infectious Diseases 65(5): 764-771.
- Houwing-Duistermaat, J.J.; Uh, H.W. & Gusnanto, A. (2017), Discussion on the paper 'Statistical contributions to bioinformatics: Design, modelling, structure learning and integration' by Jeffrey S. Morris and Veerabhadran Baladandayuthapani, Statistical Modelling 17(4-5): 319-326.
- Ghorbanoghli, Z.; Nieuwenhuis, M.H.; Houwing-Duistermaat, J.J.; Jagmohan-Changur, S.; Hes, F.J.; Tops, C.M.; Wagner, A.; Aalfs, C.M.; Verhoef, S.; Garcia, E.B.G.; Sijmons, R.H.; Menko, F.H.; Letteboer, T.G.; Hoogerbrugge, N.; Wezel, T. van; Vasen, H.F.A. & Wijnen, J.T. (2016), Colorectal cancer risk variants at 8q23.3 and 11q23.1 are associated with disease phenotype in APC mutation carriers, Familial Cancer 15(4): 563-570.
- Wammes, L.J.; Hamid, F.; Wiria, A.E.; May, L.; Kaisar, M.M.M.; Prasetyani-Gieseler, M.A.; Djuardi, Y.; Wibowo, H.; Kruize, Y.C.M.; Verweij, J.J.; Jong, S.E. de; Tsonaka, R.; Houwing-Duistermaat, J.J.; Sartono, E.; Luty, A.J.F.; Supali, T. & Yazdanbakhsh, M. (2016), Community deworming alleviates geohelminth-induced immune hyporesponsiveness, Proceedings of the National Academy of Sciences 113(44): 12526-12531.
- Bouhaddani, S. el; Houwing-Duistermaat, J.; Salo, P.; Perola, M.; Jongbloed, G. & Uh, H.W. (2016), Evaluation of O2PLS in Omics data integration, BMC Bioinformatics 17.
- Teumer, A.; Qi, Q.B.; Nethander, M.; Aschard, H.; Bandinelli, S.; Beekman, M.; Berndt, S.I.; Bidlingmaier, M.; Broer, L.; Cappola, A.; Ceda, G.P.; Chanock, S.; Chen, M.H.; Chen, T.C.; Chen, Y.D.I.; Chung, J.; Miglianico, F.D.; Eriksson, J.; Ferrucci, L.; Friedrich, N.; Gnewuch, C.; Goodarzi, M.O.; Grarup, N.; Guo, T.W.; Hammer, E.; Hayes, R.B.; Hicks, A.A.; Hofman, A.; Houwing-Duistermaat, J.J.; Hu, F.; Hunter, D.J.; Husemoen, L.L.; Isaacs, A.; Jacobs, K.B.; Janssen, J.A.M.J.L.; Jansson, J.O.; Jehmlich, N.; Johnson, S.; Juul, A.; Karlsson, M.; Kilpelainen, T.O.; Kovacs, P.; Kraft, P.; Li, C.; Linneberg, A.; Liu, Y.M.; Loos, R.J.F.; Lorentzon, M.; Lu, Y.C.; Maggio, M.; Magi, R.; Meigs, J.; Mellstrom, D.; Nauck, M.; Newman, A.B.; Pollak, M.N.; Pramstaller, P.P.; Prokopenko, I.; Psaty, B.M.; Reincke, M.; Rimm, E.B.; Rotter, J.I.; Saint Pierre, A.; Schurmann, C.; Seshadri, S.; Sjogren, K.; Slagboom, P.E.; Strickler, H.D.; Stumvoll, M.; Suh, Y.S.; Sun, Q.; Zhang, C.L.; Svensson, J.; Tanaka, T.; Tare, A.; Tonjes, A.; Uh, H.W.; Duijn, C.M. van; Heemst, D. van; Vandenput, L.; Vasan, R.S.; Volker, U.; Willems, S.M.; Ohlsson, C.; Wallaschofski, H.; Kaplan, R.C.; CHARGE Longevity Working Grp & Body Composition Genetics Consorti (2016), Genomewide meta-analysis identifies loci associated with IGF-I and IGFBP-3 levels with impact on age-related traits, Aging Cell 15(5): 811-824.
- Djuardi, Y.; Supali, T.; Wibowo, H.; Heijmans, B.T.; Deelen, J.; Slagboom, E.P.; Houwing-Duistermaat, J.J.; Sartono, E. & Yazdanbakhsh, M. (2016), Maternal and child cytokine relationship in early life is not altered by cytokine gene polymorphisms, Genes and Immunity 17(7): 380-385.
- Rest, O. van de; Schutte, B.A.M.; Deelen, J.; Stassen, S.A.M.; Akker, E.B. van den; Heemst, D. van; Dibbets-Schneider, P.; Dipten-Van Der Veen, R.A. van; Kelderman, M.; Hankemeier, T.; Mooijaart, S.P.; Grond, J. van der; Houwing-Duistermaat, J.J.; Beekman, M.; Feskens, E.J.M. & Slagboom, P.E. (2016), Metabolic effects of a 13-weeks lifestyle intervention in older adults: The Growing Old Together Study, Aging 8(1): 111-126.
- Liu, F.; Hamer, M.A.; Deelen, J.; Lall, J.S.; Jacobs, L.; Heemst, D. van; Murray, P.G.; Wollstein, A.; Craen, A.J.M. de; Uh, H.W.; Zeng, C.Q.; Hofman, A.; Uitterlinden, A.G.; Houwing-Duistermaat, J.J.; Pardo, L.M.; Beekman, M.; Slagboom, P.E.; Nijsten, T.; Kayser, M. & Gunn, D.A. (2016), The MC1R Gene and Youthful Looks, Current Biology 26(9): 1213-1220.
- Akker, E.B. van den; Pitts, S.J.; Deelen, J.; Moed, M.H.; Potluri, S.; Rooij, J. van; Suchiman, H.E.D.; Lakenberg, N.; Dijcker, W.J. de; Uitterlinden, A.G.; Kraaij, R.; Hofman, A.; Craen, A.J.M. de; Houwing-Duistermaat, J.J.; Ommen, G.J.B. van; Cox, D.R.; Meurs, J.B.J. van; Beekman, M.; Reinders, M.J.T.; Slagboom, P.E. & Genome Netherlands Consortium (2016), Uncompromised 10-year survival of oldest old carrying somatic mutations in DNMT3A and TET2, Blood 127(11): 1512-1515.
- Finken, M.J.J.; Schrevel, M.; Houwing-Duistermaat, J.J.; Kharagjitsingh, A.V.; Dekker, F.W.; Koeleman, B.P.; Roep, B.O. & Wit, J.M. (2016), Vitamin D receptor polymorphisms and growth until adulthood after very premature birth, Journal of Bone and Mineral Metabolism 34(5): 564-570.
- Auffray, C.; Balling, R.; Barroso, I.; Bencze, L.; Benson, M.; Bergeron, J.; Bernal-Delgado, E.; Blomberg, N.; Bock, C.; Conesa, A.; Signore, S. del; Delogne, C.; Devilee, P.; Meglio, A. di; Eijkemans, M.; Flicek, P.; Graf, N.; Grimm, V.; Guchelaar, H.J.; Guo, Y.K.; Gut, I.G.; Hanbury, A.; Hanif, S.; Hilgers, R.D.; Honrado, A.; Hose, D.R.; Houwing-Duistermaat, J.; Hubbard, T.; Janacek, S.H.; Karanikas, H.; Kievits, T.; Kohler, M.; Kremer, A.; Lanfear, J.; Lengauer, T.; Maes, E.; Meert, T.; Muller, W.; Nickel, D.; Oledzki, P.; Pedersen, B.; Petkovic, M.; Pliakos, K.; Rattray, M.; Mas, J.R.I.; Schneider, R.; Sengstag, T.; Serra-Picamal, X.; Spek, W.; Vaas, L.A.I.; Batenburg, O. van; Vandelaer, M.; Varnai, P.; Villoslada, P.; Vizcaino, J.A.; Wubbe, J.P.M. & Zanetti, G. (2016), Making sense of big data in health research: towards an EU action plan (vol 8, pg 71, 2016), Genome Medicine 8.
- Beekman, M.; Uh, H.W.; Heemst, D. van; Wuhrer, M.; Ruhaak, L.R.; Gonzalez-Covarrubias, V.; Hankemeier, T.; Houwing-Duistermaat, J.J. & Slagboom, P.E. (2016), Classification for Longevity Potential: The Use of Novel Biomarkers, Frontiers in Public Health 4.
- Spoel, E. van der; Rozing, M.P.; Houwing-Duistermaat, J.J.; Slagboom, P.E.; Beekman, M.; Craen, A.J.M. de; Westendorp, R.G.J. & Heemst, D. van (2015), Association analysis of insulin-like growth factor-1 axis parameters with survival and functional status in nonagenarians of the Leiden Longevity Study, Aging 7(11): 956-963.
- Reinards, T.H.C.M.; Albers, H.M.; Brinkman, D.M.C.; Kamphuis, S.S.M.; Rossum, M.A.J. van; Girschick, H.J.; Wouters, C.; Hoppenreijs, E.P.A.H.; Saurenmann, R.K.; Hinks, A.; Ellis, J.A.; Bakker, E.; Verduijn, W.; Slagboom, P.; Huizinga, T.W.J.; Toes, R.E.M.; Houwing-Duistermaat, J.J.; Cate, R. ten & Schilham, M.W. (2015), CD226 (DNAM-1) is associated with susceptibility to juvenile idiopathic arthritis, Annals of the Rheumatic Diseases 74(12): 2193-2198.
- Weller, C.M.; Wilbrink, L.A.; Houwing-Duistermaat, J.J.; Koelewijn, S.C.; Vijfhuizen, L.S.; Haan, J.; Ferrari, M.D.; Terwindt, G.M.; Maagdenberg, A.M. van den & Vries, B. de (2015), Cluster headache and the hypocretin receptor 2 reconsidered: A genetic association study and meta-analysis, Cephalalgia 35(9): 741-747.
- Punt, S.; Houwing-Duistermaat, J.J.; Schulkens, I.A.; Thijssen, V.L.; Osse, E.M.; Kroon, C.D. de; Griffioen, A.W.; Fleuren, G.J.; Gorter, A. & Jordanova, E.S. (2015), Correlations between immune response and vascularization qRT-PCR gene expression clusters in squamous cervical cancer, Molecular Cancer 14.
- Horikoshi, M.; Magi, R.; Bunt, M. van de; Surakka, I.; Sarin, A.P.; Mahajan, A.; Marullo, L.; Thorleifsson, G.; Hagg, S.; Hottenga, J.J.; Ladenvall, C.; Ried, J.S.; Winkler, T.W.; Willems, S.M.; Pervjakova, N.; Esko, T.; Beekman, M.; Nelson, C.P.; Willenborg, C.; Wiltshire, S.; Ferreira, T.; Fernandez, J.; Gaulton, K.J.; Steinthorsdottir, V.; Hamsten, A.; Magnusson, P.K.E.; Willemsen, G.; Milaneschi, Y.; Robertson, N.R.; Groves, C.J.; Bennett, A.J.; Lehtimaki, T.; Viikari, J.S.; Rung, J.; Lyssenko, V.; Perola, M.; Heid, I.M.; Herder, C.; Grallert, H.; Muller-Nurasyid, M.; Roden, M.; Hypponen, E.; Isaacs, A.; Leeuwen, E.M. van; Karssen, L.C.; Mihailov, E.; Houwing-Duistermaat, J.J.; Craen, A.J.M. de; Deelen, J.; Havulinna, A.S.; Blades, M.; Hengstenberg, C.; Erdmann, J.; Schunkert, H.; Kaprio, J.; Tobin, M.D.; Samani, N.J.; Lind, L.; Salomaa, V.; Lindgren, C.M.; Slagboom, P.E.; Metspalu, A.; Duijn, C.M. van; Eriksson, J.G.; Peters, A.; Gieger, C.; Jula, A.; Groop, L.; Raitakari, O.T.; Power, C.; Penninx, B.W.J.H.; Geus, E. de; Smit, J.H.; Boomsma, D.I.; Pedersen, N.L.; Ingelsson, E.; Thorsteinsdottir, U.; Stefansson, K.; Ripatti, S.; Prokopenko, I.; McCarthy, M.I.; Morris, A.P. & Engage Consortium (2015), Discovery and Fine-Mapping of Glycaemic and Obesity-Related Trait Loci Using High-Density Imputation, PLoS Genetics 11(7).
- Hollander, W. den; Ramos, Y.F.; Bomer, N.; Elzinga, S.; Breggen, R. van der; Lakenberg, N.; Dijcker, W.J. de; Suchiman, E.H.; Duijnisveld, B.J.; Bohringer, S.; Houwing-Duistermaat, J.J.; Slagboom, E.P.; Bos, S.D.; Nelissen, R.G. & Meulenbelt, I. (2015), DISCRIMINATING BETWEEN PUTATIVE EPIGENETIC OSTEOARTHRITIS DISEASE DRIVERS AND SHEER MARKERS, Osteoarthritis and Cartilage 23: A190-A190.
- Balliu, B.; Tsonaka, R.; Boehringer, S. & Houwing-Duistermaat, J. (2015), A Retrospective Likelihood Approach for Efficient Integration of Multiple Omics Factors in Case-Control Association Studies.
- Rooy, D.P.C. de; Tsonaka, R.; Andersson, M.L.E.; Forslind, K.; Zhernakova, A.; Frank-Bertoncelj, M.; Kovel, C.G.F. de; Koeleman, B.P.C.; Heijde, D.M.F.M. van der; Huizinga, T.W.J.; Toes, R.E.M.; Houwing-Duistermaat, J.J.; Ospelt, C.; Svensson, B. & Helm-van Mil, A.H.M. van der (2015), Genetic Factors for the Severity of ACPA-negative Rheumatoid Arthritis in 2 Cohorts of Early Disease: A Genome-wide Study, Journal of Rheumatology 42(8): 1383-1391.
- Tsonaka, R.; Woude, D. van der & Houwing-Duistermaat, J. (2015), Marginal Genetic Effects Estimation in Family and Twin Studies Using Random-Effects Models, Biometrics 71(4): 1130-1138.
- Spagnoli, A.; Houwing-Duistermaat, J.J. & Alfo, M. (2015), Mixed-effect models for longitudinal responses with different types of dropout: an application to the Leiden 85-plus study, Journal of Applied Statistics 42(9): 1896-1910.
- Tissier, R.; Tsonaka, R. & Houwing-Duistermaat, J. (2015), Secondary Phenotype Analysis in Ascertained Family Designs: Application to the Leiden Longevity Study, Human Heredity 79(1): 47-47.
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- Hart, L.M. 't; Fritsche, A.; Nijpels, G.; Leeuwen, N. van; Donnelly, L.A.; Dekker, J.M.; Alssema, M.; Fadista, J.; Carlotti, F.; Gjesing, A.P.; Palmer, C.N.A.; Haeften, T.W. van; Herzberg-Schafer, S.A.; Simonis-Bik, A.M.C.; Houwing-Duistermaat, J.J.; Helmer, Q.; Deelen, J.; Guigas, B.; Hansen, T.; Machicao, F.; Willemsen, G.; Heine, R.J.; Kramer, M.H.H.; Holst, J.J.; Koning, E.J.P. de; Haring, H.U.; Pedersen, O.; Groop, L.; Geus, E.J.C. de; Slagboom, P.E.; Boomsma, D.I.; Eekhoff, E.M.W.; Pearson, E.R. & Diamant, M. (2013), The CTRB1/2 Locus Affects Diabetes Susceptibility and Treatment via the Incretin Pathway, Diabetes 62(9): 3275-3281.
- Ruhaak, L.R.; Koeleman, C.A.M.; Uh, H.W.; Stam, J.C.; Heemst, D. van; Maier, A.B.; Houwing-Duistermaat, J.J.; Hensbergen, P.J.; Slagboom, P.E.; Deelder, A.M. & Wuhrer, M. (2013), Targeted Biomarker Discovery by High Throughput Glycosylation Profiling of Human Plasma Alpha1-Antitrypsin and Immunoglobulin A, PLoS ONE 8(9).
- Verschuren, J.J.W.; Trompet, S.; Sampietro, M.L.; Heijmans, B.T.; Koch, W.; Kastrati, A.; Houwing-Duistermaat, J.J.; Slagboom, P.E.; Quax, P.H.A. & Jukema, J.W. (2013), Pathway Analysis Using Genome-Wide Association Study Data for Coronary Restenosis - A Potential Role for the PARVB Gene, PLoS ONE 8(8).
- Gonzalez-Covarrubias, V.; Beekman, M.; Uh, H.W.; Dane, A.; Troost, J.; Paliukhovich, I.; Kloet, F.M. van der; Houwing-Duistermaat, J.; Vreeken, R.J.; Hankemeier, T. & Slagboom, E.P. (2013), Lipidomics of familial longevity, Aging Cell 12(3): 426-434.
- Visser, M.C.H. de; Minkelen, R. van; Marion, V. van; Heijer, M. den; Eikenboom, J.; Vos, H.L.; Slagboom, P.E.; Houwing-Duistermaat, J.J.; Rosendaal, F.R. & Bertina, R.M. (2013), Genome-wide linkage scan in affected sibling pairs identifies novel susceptibility region for venous thromboembolism: Genetics In Familial Thrombosis study, Journal of Thrombosis and Haemostasis 11(8): 1474-1484.
- Trouw, L.A.; Daha, N.; Kurreeman, F.A.S.; Bohringer, S.; Goulielmos, G.N.; Westra, H.J.; Zhernakova, A.; Franke, L.; Stahl, E.A.; Levarht, E.W.N.; Stoeken-Rijsbergen, G.; Verduijn, W.; Roos, A.; Li, Y.; Houwing-Duistermaat, J.J.; Huizinga, T.W.J. & Toes, R.E.M. (2013), Genetic variants in the region of the C1q genes are associated with rheumatoid arthritis, Clinical and Experimental Immunology 173(1): 76-83.
- Rooy, D.P.C. de; Yeremenko, N.G.; Wilson, A.G.; Knevel, R.; Lindqvist, E.; Saxne, T.; Krabben, A.; Leijsma, M.K.; Daha, N.A.; Tsonaka, S.; Zhernakova, A.; Houwing-Duistermaat, J.J.; Huizinga, T.W.J.; Toes, R.E.M.; Baeten, D.L.P.; Brouwer, E. & Helm-van Mil, A.H.M. van der (2013), Genetic studies on components of the Wnt signalling pathway and the severity of joint destruction in rheumatoid arthritis, Annals of the Rheumatic Diseases 72(5): 769-775.
- Tsonaka, R.; Visser, M.C.H. de & Houwing-Duistermaat, J. (2013), Estimation of genetic effects in multiple cases family studies using penalized maximum likelihood methodology, Biostatistics 14(2): 220-231.
- Ye, K.; Beekman, M.; Lameijer, E.W.; Zhang, Y.J.; Moed, M.H.; Akker, E.B. van den; Deelen, J.; Houwing-Duistermaat, J.J.; Kremer, D.; Anvar, S.Y.; Laros, J.F.J.; Jones, D.; Raine, K.; Blackburne, B.; Potluri, S.; Long, Q.; Guryev, V.; Breggen, R. van der; Westendorp, R.G.J.; Hoen, P.A.C. 't; Dunnen, J. den; Ommen, G.J.B. van; Willemsen, G.; Pitts, S.J.; Cox, D.R.; Ning, Z.M.; Boomsma, D.I. & Slagboom, P.E. (2013), Aging as Accelerated Accumulation of Somatic Variants: Whole-Genome Sequencing of Centenarian and Middle-Aged Monozygotic Twin Pairs, Twin Research and Human Genetics 16(6): 1026-1032.
- Ghahramanzadeh, R.; Esselink, G.; Kodde, L.P.; Duistermaat, H.; Valkenburg, J.L.C.H. van; Marashi, S.H.; Smulders, M.J.M. & Wiel, C.C.M. van de (2013), Efficient distinction of invasive aquatic plant species from non-invasive related species using DNA barcoding, Molecular Ecology Resources 13(1): 21-31.
- Lauc, G.; Huffman, J.E.; Pucic, M.; Zgaga, L.; Adamczyk, B.; Muzinic, A.; Novokmet, M.; Polasek, O.; Gornik, O.; Kristic, J.; Keser, T.; Vitart, V.; Scheijen, B.; Uh, H.W.; Molokhia, M.; Patrick, A.L.; McKeigue, P.; Kolcic, I.; Lukic, I.K.; Swann, O.; Leeuwen, F.N. van; Ruhaak, L.R.; Houwing-Duistermaat, J.J.; Slagboom, P.E.; Beekman, M.; Craen, A.J.M. de; Deelder, A.M.; Zeng, Q.; Wang, W.; Hastie, N.D.; Gyllensten, U.; Wilson, J.F.; Wuhrer, M.; Wright, A.F.; Rudd, P.M.; Hayward, C.; Aulchenko, Y.; Campbell, H. & Rudan, I. (2013), Loci Associated with N-Glycosylation of Human Immunoglobulin G Show Pleiotropy with Autoimmune Diseases and Haematological Cancers, PLoS Genetics 9(1): -.
- Beekman, M.; Blanche, H.; Perola, M.; Hervonen, A.; Bezrukov, V.; Sikora, E.; Flachsbart, F.; Christiansen, L.; Craen, A.J.M. de; Kirkwood, T.B.L.; Rea, I.M.; Poulain, M.; Robine, J.M.; Valensin, S.; Stazi, M.A.; Passarino, G.; Deiana, L.; Gonos, E.S.; Paternoster, L.; Sorensen, T.I.A.; Tan, Q.H.; Helmer, Q.; Akker, E.B. van den; Deelen, J.; Martella, F.; Cordell, H.J.; Ayers, K.L.; Vaupel, J.W.; Tornwall, O.; Johnson, T.E.; Schreiber, S.; Lathrop, M.; Skytthe, A.; Westendorp, R.G.J.; Christensen, K.; Gampe, J.; Nebel, A.; Houwing-Duistermaat, J.J.; Slagboom, P.E.; Franceschi, C. & GEHA Consortium (2013), Genome-wide linkage analysis for human longevity: Genetics of Healthy Aging Study., Aging Cell.
- Porcu, E.; Medici, M.; Pistis, G.; Volpato, C.B.; Wilson, S.G.; Cappola, A.R.; Bos, S.D.; Deelen, J.; Heijer, M. den; Freathy, R.M.; Lahti, J.; Liu, C.Y.; Lopez, L.M.; Nolte, I.M.; O'Connell, J.R.; Tanaka, T.; Trompet, S.; Arnold, A.; Bandinelli, S.; Beekman, M.; Bohringer, S.; Brown, S.J.; Buckley, B.M.; Camaschella, C.; Craen, A.J.M. de; Davies, G.; Visser, M.C.H. de; Ford, I.; Forsen, T.; Frayling, T.M.; Fugazzola, L.; Gogele, M.; Hattersley, A.T.; Hermus, A.R.; Hofman, A.; Houwing-Duistermaat, J.J.; Jensen, R.A.; Kajantie, E.; Kloppenburg, M.; Lim, E.M.; Masciullo, C.; Mariotti, S.; Minelli, C.; Mitchell, B.D.; Nagaraja, R.; Netea-Maier, R.T.; Palotie, A.; Persani, L.; Piras, M.G.; Psaty, B.M.; Raikkonen, K.; Richards, J.B.; Rivadeneira, F.; Sala, C.; Sabra, M.M.; Sattar, N.; Shields, B.M.; Soranzo, N.; Starr, J.M.; Stott, D.J.; Sweep, F.C.G.J.; Usala, G.; Klauw, M.M. van der; Heemst, D. van; Mullem, A. van; Vermeulen, S.H.; Visser, W.E.; Walsh, J.P.; Westendorp, R.G.J.; Widen, E.; Zhai, G.J.; Cucca, F.; Deary, I.J.; Eriksson, J.G.; Ferrucci, L.; Fox, C.S.; Jukema, J.W.; Kiemeney, L.A.; Pramstaller, P.P.; Schlessinger, D.; Shuldiner, A.R.; Slagboom, E.P.; Uitterlinden, A.G.; Vaidya, B.; Visser, T.J.; Wolffenbuttel, B.H.R.; Meulenbelt, I.; Rotter, J.I.; Spector, T.D.; Hicks, A.A.; Toniolo, D.; Sanna, S.; Peeters, R.P. & Naitza, S. (2013), A Meta-Analysis of Thyroid-Related Traits Reveals Novel Loci and Gender-Specific Differences in the Regulation of Thyroid Function, PLoS Genetics 9(2).
- Rooy, D.P.C. de; Zhernakova, A.; Tsonaka, R.; Willemze, A.; Kurreeman, B.A.S.; Toes, R.E.M.; Huizinga, T.W.J.; Houwing-Duistermaat, J.J.; Gregersen, P.K. & Helm-van Mil, A.H.M. van der (2013), A GENETIC VARIANT IN THE REGION OF MMP-9 IS ASSOCIATED WITH SERUM LEVELS AND PROGRESSION OF JOINT DAMAGE IN RHEUMATOID ARTHRITIS, Annals of the Rheumatic Diseases 72: A48-A48.
- Willemze, A.; Bohringer, S.; Knevel, R.; Levarht, E.W.N.; Stoeken-Rijsbergen, G.; Houwing-Duistermaat, J.J.; Helm-van Mil, A.H.M. van der; Huizinga, T.W.J.; Toes, R.E.M. & Trouw, L.A. (2012), The ACPA recognition profile and subgrouping of ACPA-positive RA patients, Annals of the Rheumatic Diseases 71(2): 268-274.
- Passtoors, W.M.; Boer, J.M.; Goeman, J.J.; Akker, E.B. van den; Deelen, J.; Zwaan, B.J.; Scarborough, A.; Breggen, R. van der; Vossen, R.H.A.M.; Houwing-Duistermaat, J.J.; Ommen, G.J.B. van; Westendorp, R.G.J.; Heemst, D. van; Craen, A.J.M. de; White, A.J.; Gunn, D.A.; Beekman, M. & Slagboom, P.E. (2012), Transcriptional Profiling of Human Familial Longevity Indicates a Role for ASF1A and IL7R., PLoS ONE 7(1): e27759.
- Tsonaka, R.; Visser, M.C.H. de & Houwing-Duistermaat, J. (2012), Estimation of genetic effects in ascertained case-control family studies using penalized maximum likelihood methodology.
- Out, A.A.; Wasielewski, M.; Huijts, P.E.A.; Minderhout, I.J.H.M. van; Houwing-Duistermaat, J.J.; Tops, C.M.J.; Nielsen, M.; Seynaeve, C.; Wijnen, J.T.; Breuning, M.H.; Asperen, C.J. van; Schutte, M.; Hes, F.J. & Devilee, P. (2012), MUTYH gene variants and breast cancer in a Dutch case-control study, Breast Cancer Research and Treatment 134(1): 219-227.
- Bodegom, D. van; Eriksson, U.K.; Houwing-Duistermaat, J.J. & Westendorp, R.G.J. (2012), Clustering of child mortality in a contemporary polygamous population in Africa., Biodemography and Social Biology 58(2): 162-72.
- Verschuren, J.J.W.; Trompet, S.; Postmus, I.; Sampietro, M.L.; Heijmans, B.T.; Houwing-Duistermaat, J.J.; Slagboom, P.E. & Jukema, J.W. (2012), Systematic Testing of Literature Reported Genetic Variation Associated with Coronary Restenosis: Results of the GENDER Study, PLoS ONE 7(8): -.
- Knevel, R.; Krabben, A.; Brouwer, E.; Posthumus; Wilson, A.G.; Saxne, T.; Lindqvist, E.; Rooy, D.P.C. de; Daha, N.A.; Linden, M.P.M. van der; Stoeken-Rijsbergen, G.; Toorn, L. van; Koeleman, B.F.C.; Tsonaka, S.; Zhernakova, A.; Houwing-Duistermaat, J.J.; Toes, R.E.M.; Huizinga, T.W.J. & Helm-van Mil, A.H.M. van der (2012), GENETIC VARIANTS IN IL-15 ASSOCIATE WITH PROGRESSION OF JOINT DESTRUCTION IN RHEUMATOID ARTHRITIS, A MULTI COHORT STUDY, Annals of the Rheumatic Diseases 71: -.
- Woude, D. van der; Houwing-Duistermaat, J.J.; Morgan, A.; Worthington, J.; Huizinga, T.W.J.; Roep, B.O.; Toes, R.M. & Vries, R.R.P. de (2012), THE CONTRIBUTION OF GENETIC RISK FACTORS OTHER THAN THE HLA SHARED EPITOPE ALLELES TO THE GENETIC VARIANCE OF RHEUMATOID ARTHRITIS, Annals of the Rheumatic Diseases 71: A52-A52.
- Knevel, R.; Klein, K.; Somers, K.; Ospelt, C.; Houwing-Duistermaat, J.J.; Nies, J. van; Rooy, D.P.C. de; Bock, L. de; Schonkeren, J.; Stoeken-Rijsbergen, G.; Kiridly, J.; Rodriguez-Rodriguez, L.; Helmer, Q.; Sinissen, P.; Huizinga, T.W.J.; Toes, R.E.M.; Gay, S.; Gregersen, P.K.; Somers, V. & Helm-van Mil, A.H.M. van der (2012), Genome-Wide Association Study On the Severity of Joint Destruction in Autoantibody Positive Rheumatoid Arthritis Identifies a Role for Sperm Associated Antigen 16, Arthritis and Rheumatism 64(10): S1132-S1132.
- Houwing-Duistermaat, J.J. (2012), Detecting genetic variants for extreme aging using multiple data sources., European Journal of Human Genetics.
- Tsonaka, R. & Houwing-Duistermaat, J.J. (2012), Gene-Set Testing On Autosomes And Sex Chromosomes For Complex Phenotypes: An Application In Follow-Up Data For Rheumatoid Arthritis, Genetic Epidemiology 36(2): 161-161.
- Rooy, D.P.C. de; Yeremenko, N.G.; Wilson, A.G.; Knevel, R.; Lindqvist, E.; Saxne, T.; Krabben, A.; Leijsma, M.K.; Daha, N.A.; Tsonaka, S.; Zhernakova, A.; Houwing-Duistermaat, J.J.; Huizinga, T.W.J.; Toes, R.E.M.; Baeten, D.L.P.; Brouwer, E. & Helm-van Mil, A.H.M. van der (2012), Genetic studies on components of the Wnt signalling pathway and the severity of joint destruction in rheumatoid arthritis., Annals of the Rheumatic Diseases.
- Knevel, R.; Rooy, D.P. de; Gregersen, P.K.; Lindqvist, E.; Wilson, A.G.; Grondal, G.; Zhernakova, A.; Nies, J.A. van; Toes, R.E.; Tsonaka, R.; Houwing-Duistermaat, J.J.; Steinsson, K.; Huizinga, T.W.; Saxne, T. & Helm-van Mil, A.H. van der (2012), Studying associations between variants in TRAF1-C5 and TNFAIP3-OLIG3 and the progression of joint destruction in rheumatoid arthritis in multiple cohorts, Annals of the Rheumatic Diseases 71(10): 1753-U226.
- Rooy, D.P.C. de; Zhernakova, A.; Tsonaka, R.; Kurreeman, F.; Toes, R.E.M.; Huizinga, T.W.J.; Houwing-Duistermaat, J.; Gregersen, P.K. & Helm-van Mil, A.H.M. van der (2012), New Genetic Risk Loci for the Radiographic Severity of Rheumatoid Arthritis, Arthritis and Rheumatism 64(10): S421-S422.
- Zeggini, E.; Panoutsopoulou, K.; Southam, L.; Rayner, N.W.; Day-Williams, A.G.; Lopes, M.C.; Boraska, V.; Esko, T.; Evangelou, E.; Hofman, A.; Houwing-Duistermaat, J.J.; Ingvarsson, T.; Jonsdottir, I.; Jonsson, H.; Kerkhof, H.J.M.; Kloppenburg, M.; Bos, S.D.; Mangino, M.; Metrustry, S.; Slagboom, P.E.; Thorleifsson, G.; Raine, E.V.A.; Ratnayake, M.; Ricketts, M.; Beazley, C.; Blackburn, H.; Bumpstead, S.; Elliott, K.S.; Hunt, S.E.; Potter, S.C.; Shin, S.Y.; Yadav, V.K.; Zhai, G.J.; Sherburn, K.; Dixon, K.; Arden, E.; Aslam, N.; Battley, P.K.; Carluke, I.; Doherty, S.; Gordon, A.; Joseph, J.; Keen, R.; Koller, N.C.; Mitchell, S.; O'Neill, F.; Paling, E.; Reed, M.R.; Rivadeneira, F.; Swift, D.; Walker, K.; Watkins, B.; Wheeler, M.; Birrell, F.; Ioannidis, J.P.A.; Meulenbelt, I.; Metspalu, A.; Rai, A.; Salter, D.; Stefansson, K.; Styrkarsdottir, U.; Uitterlinden, A.G.; Meurs, J.B.J. van; Chapman, K.; Deloukas, P.; Ollier, W.E.R.; Wallis, G.A.; Arden, N.; Carr, A.; Doherty, M.; McCaskie, A.; Wilkinson, J.M.; Ralston, S.H.; Valdes, A.M.; Spector, T.D.; Loughlin, J. & arcOGEN Consortium & arcOGEN Colla (2012), Identification of new susceptibility loci for osteoarthritis (arcOGEN): a genome-wide association study, Lancet 380(9844): 815-823.
- Balliu, B.; Tsonaka, R.; Woude, D. van der; Bohringer, S. & Houwing-Duistermaat, J. (2012), Modeling The Non-Inherited Maternal Antigens Effect In Multi-Case Families, Genetic Epidemiology 36(2): 129-129.
- Passtoors, W.M.; Boer, J.M.; Goeman, J.J.; Akker, E.B. van den; Deelen, J.; Zwaan, B.J.; Scarborough, A.; Breggen, R. van der; Vossen, R.H.A.M.; Houwing-Duistermaat, J.J.; Ommen, G.J.B. van; Westendorp, R.G.J.; Heemst, D. van; Craen, A.J.M. de; White, A.J.; Gunn, D.A.; Beekman, M. & Slagboom, P.E. (2012), Transcriptional Profiling of Human Familial Longevity Indicates a Role for ASF1A and IL7R, PLoS ONE 7(1): -.
- Uh HW, Deelen J, Beekman M, Helmer Q, Rivadeneira F, Hottenga JJ, Boomsma DI, Hofman A, Uitterlinden AG, Slagboom PE, Böhringer S & Houwing-Duistermaat JJ (2012), How to deal with the early GWAS data when imputting and combining different arrays is necessary, European Journal of Human Genetics.
- Jansen, D.T.S.L.; Daha, N.; Kurreeman, F.A.S.; Bohringer, S.; Stoeken-Rijsbergen, G.; Houwing-Duistermaat, J.J.; Huizinga, T.W.; Toes, R.E.M. & Trouw, L.A. (2012), GENETIC VARIANTS OF C1Q ARE A RISK FOR RHEUMATOID ARTHRITIS, Annals of the Rheumatic Diseases 71: A54-A54.
- Uh, H.W.; Tsonaka, R.; Wuhrer, M.; Slagboom, E. & Houwing-Duistermaat, J. (2012), Integrating Multiple Glycans and Genetic Data Using Joint Modeling Techniques: An Application in Leiden Longevity Study, Genetic Epidemiology 36(7): 777-777.
- Willemze, A.; Woude, D. van der; Ghidey, W.; Levarht, E.W.N.; Stoeken-Rijsbergen, G.; Verduyn, W.; Vries, R.R.P. de; Houwing-Duistermaat, J.J.; Huizinga, T.W.J.; Trouw, L.A. & Toes, R.E.M. (2011), The Interaction Between HLA Shared Epitope Alleles and Smoking and Its Contribution to Autoimmunity Against Several Citrullinated Antigens, Arthritis and Rheumatism 63(7): 1823-1832.
- Trouw, L.A.; Bohringer, S.; Daha, N.A.; Stahl, E.A.; Raychaudhuri, S.; Kurreeman, F.A.; Stoeken-Rijsbergen, G.; Houwing-Duistermaat, J.J.; Huizinga, T.W. & Toes, R.E. (2011), The major risk alleles of age-related macular degeneration (AMD) in CFH do not play a major role in rheumatoid arthritis (RA)., Clinical and Experimental Immunology 166(3): 333-7.
- Willemze, A.; Bohringer, S.; Knevel, R.; Levarht, E.W.N.; Stoeken-Rijsbergen, G.; Houwing-Duistermaat, J.J.; Helm-van Mil, A.H.M. van der; Huizinga, T.W.J.; Toes, R.E.M. & Trouw, L.A. (2011), The ACPA recognition profile and subgrouping of ACPA-positive RA patients., Annals of the Rheumatic Diseases.
- Shi, J.; Bohringer, S.; Stahl, E.A.; Raychaudhuri, S.; Kurreeman, F.A.; Houwing-Duistermaat, J.J.; Huizinga, T.W.; Toes, R.E. & Trouw, L.A. (2011), THE MAJOR RISK ALLELES OF AGE RELATED MACULAR DEGENERATION IN CFH, DO NOT PLAY A MAJOR ROLE IN RHEUMATOID ARTHRITIS, Annals of the Rheumatic Diseases 70.
- Trouw, L.A.; Kurreeman, F.A.S.; Daha, N.; Bohringer, S.; Stoeken-Rijsbergen, G.; Houwing-Duistermaat, J.J.; Huizinga, T.W. & Toes, R.E. (2011), GENETIC VARIANTS OF C1Q ARE A RISK FOR RHEUMATOID ARTHRITIS, Annals of the Rheumatic Diseases 70: A17A17.
- Daha, N.A.; Willemze, A.; Robinson, D.B.; Oen, K.G.; Smolik, I.; Hart, D.; Ghidey, W.; Houwing-Duistermaat, J.J.; Siminovitch, K.A.; Huizinga, T.W.J.; El-Gabalawy, H.S. & Toes, R.E.M. (2011), GENETIC INTERACTION IN THE SUSCEPTIBILITY OF RHEUMATOID ARTHRITIS, Annals of the Rheumatic Diseases 70: A84A84.
- Uh, H.W.; Deelen, J.; Beekman, M.; Helmer, Q.; Rivadeneira, F.; Hottenga, J.J.; Boomsma, D.I.; Hofman, A.; Uitterlinden, A.G.; Slagboom, P.E.; Bohringer, S. & Houwing-Duistermaat, J.J. (2011), How to deal with the early GWAS data when imputing and combining different arrays is necessary., European Journal of Human Genetics.
- Meulenbelt, I.; Bos, S.D.; Chapman, K.; Breggen, R. van der; Houwing-Duistermaat, J.J.; Kremer, D.; Kloppenburg, M.; Carr, A.; Tsezou, A.; Gonzalez, A.; Loughlin, J. & Slagboom, E. (2011), Meta-analyses of genes modulating intracellular T3 bio-availability reveal a possible role for the DIO3 gene in osteoarthritis susceptibility, Annals of the Rheumatic Diseases 70(1): 164-167.
- Tsonaka, R.; Helm-van Mil, A.H.M. van der & Houwing-Duistermaat, J.J. (2011), A two-stage mixed-effects model approach for gene-set analyses in candidate gene studies.
- Martella, F.; Vermunt, J.K.; Beekman, M.; Westendorp, R.G.J.; Slagboom, P.E. & Houwing-Duistermaat, J.J. (2011), A mixture model with random-effects components for classifying sibling pairs, Statistics in Medicine 30(27): 3252-3264.
- Houwing-Duistermaat JJ, Uh HW & Tsonaka R (2011), Pathway analysis for family data using nested random-effects models., BMC Proceedings 5 Suppl 9: S22.
- Martella, F.; Vermunt, J.K.; Beekman, M.; Westendorp, R.G.J.; Slagboom, P.E. & Houwing-Duistermaat, J.J. (2011), A mixture model with random-effects components for classifying sibling pairs, Statistics in Medicine.
- Bickeboller, H.; Houwing-Duistermaat, J.J.; Wang, X.F. & Yan, X.T. (2011), Dealing with high dimensionality for the identification of common and rare variants as main effects and for gene-environment interaction, Genetic Epidemiology.
- Daha NA, Kurreeman FAS, Böhringer S, Stoeken-Rijsbergen G, Houwing-Duistermaat JJ, Huizinga TW, Toes REM & Trouw LA (2011), Genetic variants of C1q are a risk for rheumatoid arthritis, Molecular Immunology.
- Uh H-W, Tsonaka R & Houwing-Duistermaat JJ (2011), Does pathway analysis make it easier for common variants to tag rare ones?
- Waarsing, J.H.; Kloppenburg, M.; Slagboom, P.E.; Kroon, H.M.; Houwing-Duistermaat, J.J.; Weinans, H. & Meulenbelt, I. (2011), Osteoarthritis Susceptibility Genes Influence the Association Between Hip Morphology and Osteoarthritis, Arthritis and Rheumatism 63(5): 1349-1354.
- Houwing-Duistermaat JJ, Uh HW & Tsonaka R. (2011), Pathway Analysis using Nested Random Effects Models for SNPs.
- El-Gabalawy, H.S.; Robinson, D.B.; Daha, N.A.; Oen, K.G.; Smolik, I.; Elias, B.; Hart, D.; Bernstein, C.N.; Sun, Y.; Lu, Y.; Houwing-Duistermaat, J.J. & Siminovitch, K.A. (2011), Non-HLA genes modulate the risk of rheumatoid arthritis associated with HLA-DRB1 in a susceptible North American Native population, Genes and Immunity 12(7): 568-574.
- Willemze, A.; Bohringer, S.; Knevel, R.; Levarht, E.W.N.; Stoeken-Rijsbergen, G.; Houwing-Duistermaat, J.J.; Helm-van Mil, A.H.M. van der; Huizinga, T.W.J.; Toes, R.E.M. & Trouw, L.A. (2011), The ACPA Recognition Profile and Sub-Grouping of APCA Positive Rheumatoid Arthritis Patients., Arthritis and Rheumatism 63(10): S849-S850.
- Willemze, A.; Woude, D. van der; Ghidey, W.; Levarht, E.W.N.; Stoeken-Rijsbergen, G.; Verduyn, W.; Vries, R.R.P. de; Houwing-Duistermaat, J.J.; Huizinga, T.W.J.; Trouw, L.A. & Toes, R.E.M. (2011), The interaction between HLA shared epitope alleles and smoking and its contribution to autoimmunity against several citrullinated antigens., Arthritis and Rheumatism 63(7): 1823-32.
- Landt, M.C.T.S.O. 't; Meulenbelt, I.; Bartels, M.; Suchiman, E.; Middeldorp, C.M.; Houwing-Duistermaat, J.J.; Trier, J. van; Onkenhout, E.J.; Vink, J.M.; Beijsterveldt, C.E.M. van; Brandys, M.K.; Sanders, N.; Zipfel, S.; Herzog, W.; Herpertz-Dahlmann, B.; Klampfl, K.; Fleischhaker, C.; Zeeck, A.; Zwaan, M. de; Herpertz, S.; Ehrlich, S.; Elburg, A.A. van; Adan, R.A.H.; Scherag, S.; Hinney, A.; Hebebrand, J.; Boomsma, D.I.; Furth, E.F. van & Slagboom, P.E. (2011), Association study in eating disorders: TPH2 associates with anorexia nervosa and self-induced vomiting, Genes, Brain and Behavior 10(2): 236-243.
- Emonts, M.; Hazes, M.J.M.W.; Houwing-Duistermaat, J.J.; Gaast-de Jongh, C.E. van der; Vogel, L. de; Han, H.K.H.; Wouters, J.M.G.W.; Laman, J.D. & Dolhain, R.J.E.M. (2011), Polymorphisms in genes controlling inflammation and tissue repair in rheumatoid arthritis: a case control study, BMC Medical Genetics 12.
- Bickeboller, H.; Houwing-Duistermaat, J.J.; Wang, X.F. & Yan, X.T. (2011), Dealing with high dimensionality for the identification of common and rare variants as main effects and for gene-environment interaction, Genetic Epidemiology 35: S35-S40.
- Deelen, J.; Uh, H.W.; Monajemi, R.; Heemst, D. van; Thijssen, P.E.; Bohringer, S.; Akker, E.B. van den; Craen, A.J.M. de; Rivadeneira, F.; Uitterlinden, A.G.; Westendorp, R.G.J.; Goeman, J.J.; Slagboom, P.E.; Houwing-Duistermaat, J.J. & Beekman, M. (2011), Gene set analysis of GWAS data for human longevity highlights the relevance of the insulin/IGF-1 signaling and telomere maintenance pathways., AGE.
- Deelen, J.; Beekman, M.; Uh, H.W.; Helmer, Q.; Kuningas, M.; Christiansen, L.; Kremer, D.; Breggen, R. van der; Suchiman, H.E.D.; Lakenberg, N.; Akker, E.B. van den; Passtoors, W.M.; Tiemeier, H.; Heemst, D. van; Craen, A.J. de; Rivadeneira, F.; Geus, E.J. de; Perola, M.; Ouderaa, F.J. van der; Gunn, D.A.; Boomsma, D.I.; Uitterlinden, A.G.; Christensen, K.; Duijn, C.M. van; Heijmans, B.T.; Houwing-Duistermaat, J.J.; Westendorp, R.G.J. & Slagboom, P.E. (2011), Genome-wide association study identifies a single major locus contributing to survival into old age; the APOE locus revisited, Aging Cell 10(4): 686-698.
- Ruhaak, L.R.; Uh, H.W.; Beekman, M.; Hokke, C.H.; Westendorp, R.G.J.; Houwing-Duistermaat, J.; Wuhrer, M.; Deelder, A.M. & Sagboom, P.E. (2010), Plasma protein N-glycan profiles are associated with calendar age, familial longevity and health., Journal of Proteome Research.
- Albers, H.M.; Brinkman, D.M.C.; Kamphuis, S.S.M.; Suijlekom-Smit, L.W.A. van; Rossum, M.A.J. van; Hoppenreijs, E.P.A.H.; Girschick, H.J.; Wouters, C.; Saurenmann, R.K.; Houwing-Duistermaat, J.J.; Huizinga, T.W.J.; Schilham, M.W. & Cate, R. ten (2010), Clinical Course and Prognostic Value of Disease Activity in the First Two Years in Different Subtypes of Juvenile Idiopathic Arthritis, Arthritis Care & Research 62(2): 204-212.
- Hart, L.M. 't; Simonis-Bik, A.M.; Nijpels, G.; Haeften, T.W. van; Schafer, S.A.; Houwing-Duistermaat, J.J.; Boomsma, D.I.; Groenewoud, M.J.; Reiling, E.; Hove, E.C. van; Diamant, M.; Kramer, M.H.H.; Heine, R.J.; Maassen, J.A.; Kirchhoff, K.; Machicao, F.; Haring, H.U.; Slagboom, P.E.; Willemsen, G.; Eekhoff, E.M.; Geus, E.J. de; Dekker, J.M. & Fritsche, A. (2010), Combined Risk Allele Score of Eight Type 2 Diabetes Genes Is Associated With Reduced First-Phase Glucose-Stimulated Insulin Secretion During Hyperglycemic Clamps, Diabetes 59(1): 287-292.
- Emonts, M.; Vermont, C.L.; Houwing-Duistermaat, J.J.; Haralambous, E.; Gaast-de Jongh, C.E.; Hazelzet, J.A.; Faust, S.N.; Betts, H.; Hermans, P.W.M.; Levin, M.; Groot, R. de; St Mary's Imperial Coll Grp & Erasmus MC-Sophia Children's Hosp (2010), POLYMORPHISMS IN PARP, IL1B, IL4, IL10, C1INH, DEFB1, AND DEFA4 IN MENINGOCOCCAL DISEASE IN THREE POPULATIONS, Shock 34(1): 17-22.
- Simonis-Bik, A.M.; Nijpels, G.; Haeften, T.W. van; Houwing-Duistermaat, J.J.; Boomsma, D.I.; Reiling, E.; Hove, E.C. van; Diamant, M.; Kramer, M.H.H.; Heine, R.J.; Maassen, J.A.; Slagboom, P.E.; Willemsen, G.; Dekker, J.M.; Eekhoff, E.M.; Geus, E.J. de & Hart, L.M. 't (2010), Gene Variants in the Novel Type 2 Diabetes Loci CDC123/CAMK1D, THADA, ADAMTS9, BCL11A, and MTNR1B Affect Different Aspects of Pancreatic beta-Cell Function, Diabetes 59(1): 293-301.
- Woude, D. van der; Alemayehu, W.G.; Daha, N.A.; Verduyn, W.; Vries, R.R.P. de; Houwing-Duistermaat, J.J.; Huizinga, T.W.J. & Toes, R.E.M. (2010), A GENE - ENVIRONMENT INTERACTION BETWEEN HLA SE ALLELES AND SMOKING AFFECTS THE REACTIVITY OF ACPA TO VARIOUS CITRULLINATED ANTIGENS, Annals of the Rheumatic Diseases 69.
- Bos, S.D.; Lakenberg, N.; Breggen, R. van der; Houwing-Duistermaat, J.J.; Kloppenburg, M.; Craen, A.J.M. de; Beekman, M.; Meulenbelt, I. & Slagboom, P.E. (2010), A genome-wide linkage scan reveals CD53 as an important regulator of innate TNF-alpha levels, European Journal of Human Genetics 18(8): 953-959.
- Callegaro, A.; Meulenbelt, I.; Kloppenburg, M.; Slagboom, P.E. & Houwing-Duistermaat, J.J. (2010), Allele-Sharing Statistics Using Information on Family History, Annals of Human Genetics 74: 547-554.
- Ruhaak, L.R.; Uh, H.W.; Beekman, M.; Koeleman, C.A.M.; Hokke, C.H.; Westendorp, R.G.J.; Wuhrer, M.; Houwing-Duistermaat, J.J.; Slagboom, P.E. & Deelder, A.M. (2010), Decreased Levels of Bisecting GlcNAc Glycoforms of IgG Are Associated with Human Longevity, PLoS ONE 5(9).
- Rozing, M.P.; Houwing-Duistermaat, J.J.; Slagboom, P.E.; Beekman, M.; Frolich, M.; Craen, A.J.M. de; Westendorp, R.G.J. & Heemst, D. van (2010), Familial Longevity Is Associated with Decreased Thyroid Function, Journal of Clinical Endocrinology and Metabolism 95(11): 4979-4984.
- Woude, D. van der; Alemayehu, W.G.; Verduijn, W.; Vries, R.R.P. de; Houwing-Duistermaat, J.J.; Huizinga, T.W.J. & Toes, R.E.M. (2010), Gene-environment interaction influences the reactivity of autoantibodies to citrullinated antigens in rheumatoid arthritis, Nature Genetics 42(10): 814-816.
- Marques, R.B.; Thabet, M.M.; White, S.J.; Houwing-Duistermaat, J.J.; Bakker, A.M.; Hendriks, G.J.; Zhernakova, A.; Huizinga, T.W.; Helm-van Mil, A.H. van der & Toes, R.E. (2010), Genetic Variation of the Fc Gamma Receptor 3B Gene and Association with Rheumatoid Arthritis, PLoS ONE 5(10).
- Beekman, M.; Nederstigt, C.; Suchiman, H.E.D.; Kremer, D.; Breggen, R. van der; Lakenberg, N.; Alemayehu, W.G.; Craen, A.J.M. de; Westendorp, R.G.J.; Boomsma, D.I.; Geus, E.J.C. de; Houwing-Duistermaat, J.J.; Heijmans, B.T. & Slagboom, P.E. (2010), Genome-wide association study (GWAS)-identified disease risk alleles do not compromise human longevity, Proceedings of the National Academy of Sciences 107(42): 18046-18049.
- Bergen, C.A.M. van; Rutten, C.E.; Meijden, E.D. van der; Luxemburg-Heijs, S.A.P. van; Lurvink, E.G.A.; Houwing-Duistermaat, J.J.; Kester, M.G.D.; Mulder, A.; Willemze, R.; Falkenburg, J.H.F. & Griffioen, M. (2010), High-Throughput Characterization of 10 New Minor Histocompatibility Antigens by Whole Genome Association Scanning, Cancer Research 70(22): 9073-9083.
- Woude, D. van der; Lie, B.A.; Lundstrom, E.; Balsa, A.; Feitsma, A.L.; Houwing-Duistermaat, J.J.; Verduijn, W.; Nordang, G.B.N.; Alfredsson, L.; Klareskog, L.; Pascual-Salcedo, D.; Gonzalez-Gay, M.A.; Lopez-Nevot, M.A.; Valero, F.; Roep, B.O.; Huizinga, T.W.J.; Kvien, T.K.; Martin, J.; Padyukov, L.; Vries, R.R.P. de & Toes, R.E.M. (2010), Protection Against Anti-Citrullinated Protein Antibody-Positive Rheumatoid Arthritis Is Predominantly Associated With HLA-DRB1*1301 A Meta-Analysis of HLA-DRB1 Associations With Anti-Citrullinated Protein Antibody-Positive and Anti-Citrullinated Protein Antibody-Negative Rheumatoid Arthritis in Four European Populations, Arthritis and Rheumatism 62(5): 1236-1245.
- Nies, J.A.B. van; Knevel, R.; Daha, N.; Linden, M.P.M. van der; Gregersen, P.K.; Kern, M.; Cessie, S.; Houwing-Duistermaat, J.J.; Huizinga, T.W.J.; Toes, R.E.M. & Helm-van Mil, A.H.M. van der (2010), The PTPN22 susceptibility risk variant is not associated with the rate of joint destruction in anti-citrullinated protein antibody-positive rheumatoid arthritis, Annals of the Rheumatic Diseases 69(9): 1730U24.
- Kurreeman, F.A.S.; Goulielmos, G.N.; Alizadeh, B.Z.; Rueda, B.; Houwing-Duistermaat, J.; Sanchez, E.; Bevova, M.; Radstake, T.R.; Vonk, M.C.; Galanakis, E.; Ortego, N.; Verduyn, W.; Zervou, M.I.; Roep, B.O.; Dema, B.; Espino, L.; Urcelay, E.; Boumpas, D.T.; Berg, L.H. van den; Wijmenga, C.; Koeleman, B.P.C.; Huizinga, T.W.J.; Toes, R.E.M.; Martin, J.; AADEA Grp & SLEGEN Consortium (2010), The TRAF1-C5 region on chromosome 9q33 is associated with multiple autoimmune diseases, Annals of the Rheumatic Diseases 69(4): 696-699.
- Landt, M.C.T.S.O. 't; Meulenbelt, I.; Bartels, M.; Suchiman, E.; Middeldorp, C.M.; Houwing-Duistermaat, J.J.; Trier, J. van; Onkenhout, E.J.; Vink, J.M.; Beijsterveldt, C.E.M. van; Brandys, M.K.; Sanders, N.; Zipfel, S.; Herzog, W.; Herpertz-Dahlmann, B.; Klampfl, K.; Fleischhaker, C.; Zeeck, A.; Zwaan, M. de; Herpertz, S.; Ehrlich, S.; Elburg, A.A. van; Adan, R.A.H.; Scherag, S.; Hinney, A.; Hebebrand, J.; Boomsma, D.I.; Furth, E.F. van & Slagboom, P.E. (2010), Association study in eating disorders: TPH2 associates with anorexia nervosa and self-induced vomiting., Genes, Brain and Behavior.
- Vaarhorst, A.A.M.; Beekman, M.; Suchiman, E.H.D.; Heemst, D. van; Houwing-Duistermaat, J.J.; Westendorp, R.G.J.; Slagboom, P.E.; Heijmans, B.T.; Project Grp & Leiden Longevity Study LLS Grp (2010), Lipid metabolism in long-lived families: the Leiden Longevity Study., AGE.
- Woude, D. van der; Lie, B.A.; Lundstrom, E.; Balsa, A.; Feitsma, A.L.; Houwing-Duistermaat, J.J.; Verduijn, W.; Nordang, G.B.N.; Alfredsson, L.; Klareskog, L.; Pascual-Salcedo, D.; Gonzalez-Gay, M.A.; Lopez-Nevot, M.A.; Valero, F.; Roep, B.O.; Huizinga, T.W.J.; Kvien, T.K.; Martin, J.; Padyukov, L.; Vries, R.R.P. de & Toes, R.E.M. (2010), Protection against anti-citrullinated protein antibody-positive rheumatoid arthritis is predominantly associated with HLA-DRB1*1301: a meta-analysis of HLA-DRB1 associations with anti-citrullinated protein antibody-positive and anti-citrullinated protein antibody-negative rheumatoid arthritis in four European populations., Arthritis and Rheumatism 62(5): 1236-45.
- Middeldorp, A.; Jagmohan-Changur, S.C.; Klift, H.M. van der; Puijenbroek, M. van; Houwing-Duistermaat, J.J.; Webb, E.; Houlston, R.; Tops, C.; Vasen, H.F.A.; Devilee, P.; Morreau, H.; Wezel, T. van & Wijnen, J. (2010), Comprehensive Genetic Analysis of Seven Large Families with Mismatch Repair Proficient Colorectal Cancer, Genes, Chromosomes and Cancer 49(6): 539-548.
- Ruhaak LR, Uh HW, Beekman B, Koeleman CAM, Hokke CH, Westendorp RG, Wuhrer M, Houwing-Duistermaat JJ, Slagboom PE & Deelder AE (2010), Plasma protein N-glycan profiles are associated with calender age, familial longevity and health, Journal of Proteome Research.
- Bos, S.D.; Lakenberg, N.; Breggen, R. van der; Houwing-Duistermaat, J.J.; Kloppenburg, M.; Craen, A.J.M. de; Beekman, M.; Meulenbelt, I. & Slagboom, P.E. (2010), A genome-wide linkage scan reveals CD53 as an important regulator of innate TNF-alpha levels, European Journal of Human Genetics 18(8): 953-959.
- Uh, H.W.; Bohringer, S. & Houwing-Duistermaat, J.J. (2010), How Confident are We About the Results from a Genome-wide Association Study Using Imputed Data in Leiden Longevity Study?, Genetic Epidemiology 34(8): 951-951.
- Callegaro, A.; Lebrec, J.J.P. & Houwing-Duistermaat, J.J. (2010), Testing for Genetic Association in the Presence of Linkage and Gene-Covariate Interactions, Biometrical Journal 52(1): 22-33.
- Callegaro, A.; Lebrec, J.J.P. & Houwing-Duistermaat, J.J. (2010), Testing for genetic association in the presence of linkage and gene-covariate interactions., Biometrical Journal 52(1): 22-33.
- Callegaro, A.; Houwelingen, J.C. van & Houwing-Duistermaat, J.J. (2010), Robust age at onset linkage analysis in nuclear families., Human Heredity 69(2): 80-90.
- Albers, H.M.; Brinkman, D.M.C.; Kamphuis, S.S.M.; Suijlekom-Smit, L.W.A. van; Rossum, M.A.J. van; Hoppenreijs, E.P.A.H.; Girschick, H.J.; Wouters, C.; Saurenmann, R.K.; Houwing-Duistermaat, J.J.; Huizinga, T.W.J.; Schilham, M.W. & Cate, R. ten (2010), Clinical course and prognostic value of disease activity in the first two years in different subtypes of juvenile idiopathic arthritis.
- Callegaro, A.; Houwelingen, J.C. van & Houwing-Duistermaat, J.J. (2010), Robust Age at Onset Linkage Analysis in Nuclear Families, Human Heredity 69(2): 80-90.
- Meulenbelt, I.; Bos, S.D.; Kloppenburg, M.; Lakenberg, N.; Houwing-Duistermaat, J.J.; Watt, I.; Craen, A.J. de; Duijn, C.M. van & Slagboom, P.E. (2010), Interleukin-1 Gene Cluster Variants With Innate Cytokine Production Profiles and Osteoarthritis in Subjects From the Genetics, Osteoarthritis and Progression Study, Arthritis and Rheumatism 62(4): 1119-1126.
- Kurreeman, F.A.S.; Goulielmos, G.N.; Alizadeh, B.Z.; Rueda, B.; Houwing-Duistermaat, J.; Sanchez, E.; Bevova, M.; Radstake, T.R.; Vonk, M.C.; Galanakis, E.; Ortego, N.; Verduyn, W.; Zervou, M.I.; Roep, B.O.; Dema, B.; Espino, L.; Urcelay, E.; Boumpas, D.T.; Berg, L.H. van den; Wijmenga, C.; Koeleman, B.P.C.; Huizinga, T.W.J.; Toes, R.E.M.; Martin, J.; AADEA Grp & SLEGEN Consortium (2010), The TRAF1-C5 region on chromosome 9q33 is associated with multiple autoimmune diseases., Annals of the Rheumatic Diseases 69(4): 696-699.
- Hart, L.M. 't; Simonis-Bik, A.M.; Nijpels, G.; Haeften, T.W. van; Schafer, S.A.; Houwing-Duistermaat, J.J.; Boomsma, D.I.; Groenewoud, M.J.; Reiling, E.; Hove, E.C. van; Diamant, M.; Kramer, M.H.H.; Heine, R.J.; Maassen, J.A.; Kirchhoff, K.; Machicao, F.; Haring, H.U.; Slagboom, P.E.; Willemsen, G.; Eekhoff, E.M.; Geus, E.J. de; Dekker, J.M. & Fritsche, A. (2010), Combined risk allele score of eight type 2 diabetes genes is associated with reduced first-phase glucose-stimulated insulin secretion during hyperglycemic clamps.
- Yanbaeva DG, Dentener MA, Spruit MA, Houwing-Duistermaat JJ, Kotz D, Passos VL & Wouters EFM (2009), IL6 and CRP haplotypes are associated with COPD risk and systemic inflammation: a case-control study, BMC Medical Genetics 10.
- Houwing-Duistermaat JJ, Callegaro A, Beekman M, Westendorp RG, Slagboom PE & van Houwelingen JC (2009), Weighted statistics for aggregation and linkage analysis of human longevity in selected families: The Leiden Longevity Study, Statistics in Medicine 28(1): 140-151.
- Albers, H.M.; Kurreeman, F.A.S.; Stoeken-Rijsbergen, G.; Brinkman, D.M.C.; Kamphuis, S.S.M.; Rossum, M.A.J. van; Girschick, H.J.; Wouters, C.; Saurenmann, R.K.; Hoppenreijs, E.; Slagboom, P.; Houwing-Duistermaat, J.J.; Verduijn, W.; Huizinga, T.W.J.; Cate, R. ten; Toes, R.E.M. & Schilham, M.W. (2009), Association of the Autoimmunity Locus 4q27 With Juvenile Idiopathic Arthritis, Arthritis and Rheumatism 60(3): 901-904.
- Helmer Q, Lebrec J, Callegaro A & Houwing-Duistermaat JJ (2009), Arthur: software for weighted score tests for linkage analysis, Annals of Human Genetics 73: 669-669.
- Uh HW, Houwing-Duistermaat JJ, Putter H & van Houwelingen HC (2009), Assessment of global phase uncertainty in case-control studies, BMC Genetics 10.
- Lebrec JJ, Huizinga TW, Toes RE, Houwing-Duistermaat JJ & van Houwelingen HC (2009), Integration of gene ontology pathways with North American Rheumatoid Arthritis Consortium genome-wide association data via linear modeling., BMC Proceedings 3 Suppl 7: S94.
- Callegaro A, Uh HW, Helmer Q & Houwing-Duistermaat JJ (2009), New score tests for age-at-onset linkage analysis in general pedigrees., BMC Proceedings 3 Suppl 7: S97.
- Uh HW, Wijk HJ & Houwing-Duistermaat JJ (2009), Testing for genetic association taking into account phenotypic information of relatives., BMC Proceedings 3 Suppl 7: S123.
- Uh HW, Beekman M, Slagboom PE & Houwing-Duistermaat JJ (2009), Testing for genetic association using family data: incorporating phenotypic information of un-genotyped relatives, Annals of Human Genetics 73: 662-662.
- van der Woude D, Houwing-Duistermaat JJ, Toes REM, Huizinga TWJ, Thomson W, Worthington J, van der Helm-van Mil AHM & de Vries RRP (2009), Quantitative Heritability of Anti-Citrullinated Protein Antibody-Positive and Anti-Citrullinated Protein Antibody-Negative Rheumatoid Arthritis, Arthritis and Rheumatism 60(4): 916-923.
- van der Woude D, Houwing-Duistermaat JJ, Toes REM, Huizinga TWJ, Thomson W, Worthington J, van der Helm-van Mil AHM & de Vries RRP (2009), Quantitative Heritability of Anti-Citrullinated Protein Antibody-Positive and Anti-Citrullinated Protein Antibody-Negative Rheumatoid Arthritis, Arthritis and Rheumatism 60(4): 916-923.
- van der Woude D, Houwing-Duistermaat JJ, Toes REM, Huizinga TWJ, Thomson W, Worthington J, van der Helm-van Mil AHM & de Vries RRP (2009), Quantitative Heritability of Anti-Citrullinated Protein Antibody-Positive and Anti-Citrullinated Protein Antibody-Negative Rheumatoid Arthritis, Arthritis and Rheumatism 60(4): 916-923.
- Middeldorp A, Jagmohan-Changur S, van Eijk R, Tops C, Devilee P, Vasen HFA, Hes FJ, Houlston R, Tomlinson I, Houwing-Duistermaat JJ, Wijnen JT, Morreau H & van Wezel T (2009), Enrichment of Low Penetrance Susceptibility Loci in a Dutch Familial Colorectal Cancer Cohort, Cancer Epidemiology, Biomarkers and Prevention 18(11): 3062-3067.
- Callegaro A, van Houwelingen HC & Houwing-Duistermaat JJ (2009), Score test for age at onset genetic linkage analysis in selected sibling pairs, Statistics in Medicine 28(14): 1913-1926.
- el Galta R, van Houwelingen HC & Houwing-Duistermaat JJ (2009), Global Tests for Linkage, Biometrical Journal 51(1): 70-83.
- Houwing-Duistermaat JJ, Callegaro A, Beekman M, Westendorp RG, Slagboom PE & van Houwelingen JC (2009), Weighted statistics for aggregation and linkage analysis of human longevity in selected families: the Leiden Longevity Study., Statistics in Medicine 28(1): 140-51.
- Callegaro A, van Houwelingen HC & Houwing-Duistermaat JJ (2009), Score test for age at onset genetic linkage analysis in selected sibling pairs.
- Helderman-van den Enden AT, de Jong R, den Dunnen JT, Houwing-Duistermaat JJ, Kneppers AL, Ginjaar HB, Breuning MH & Bakker E (2009), Recurrence risk due to germ line mosaicism: Duchenne and Becker muscular dystrophy.
- Emonts M, Vermont CL, Houwing-Duistermaat JJ, Haralambous E, Gaast-de Jongh CE, Hazelzet JA, Faust SN, Betts H, Hermans PW, Levin M, de Groot R & (2009), Polymorphisms in PARP, IL1B, IL4, IL10, C1INH, DEFB1 and DEFA4 in meningococcal disease in three populations., Shock.
- Albers, H.M.; Kurreeman, F.A.S.; Stoeken-Rijsbergen, G.; Brinkman, D.M.C.; Kamphuis, S.S.M.; Rossum, M.A.J. van; Girschick, H.J.; Wouters, C.; Saurenmann, R.K.; Hoppenreijs, E.; Slagboom, P.; Houwing-Duistermaat, J.J.; Verduijn, W.; Huizinga, T.W.J.; Cate, R. ten; Toes, R.E.M. & Schilham, M.W. (2009), Association of the autoimmunity locus 4q27 with juvenile idiopathic arthritis., Arthritis and Rheumatism 60(3): 901-4.
- Callegaro A & Houwing-Duistermaat J (2009), Family-based Association Tests: Accounting for Sib-sib Correlation, Linkage Effect, and Gene-environment Interaction., Genetic Epidemiology 33(8): 763-764.
- van der Woude D, Houwing-Duistermaat JJ, Toes RE, Huizinga TW, Thomson W, Worthington J, van der Helm-van Mil AH & de Vries RR (2009), Quantitative heritability of anti-citrullinated protein antibody-positive and anti-citrullinated protein antibody-negative rheumatoid arthritis., Arthritis and Rheumatism 60(4): 916-23.
- Houwing-Duistermaat JJ, Callegaro A & Meulenbelt I (2009), Weighting of the Test Statistic by Family History Improves the Power to Detect Linkage., Genetic Epidemiology 33(8): 799-799.
- Colas F, Meulenbelt I, Houwing-Duistermaat JJ, Kloppenburg M, Watt I, van Rooden SM, Visser M, Marinus J, van Hilten JJ, Slagboom PE & Kok JN (2008), Reliability of Cluster Results for Different Types of Time Adjustments in Complex Disease Research, 2008 30TH ANNUAL INTERNATIONAL CONFERENCE OF THE IEEE ENGINEERING IN MEDICINE AND BIOLOGY SOCIETY, VOLS 1-8: 4601-4604.
- Uh HW, Hartgers FC, Yazdanbakhsh M & Houwing-Duistermaat JJ (2008), Evaluation of regression methods when immunological measurements are constrained by detection limits, BMC Immunology 9.
- Ghidey W, Stijnen T, Houwing-Duistermaat J, Heijmans B, Beekman M, Westendorp R, Slagboom E & van Houwelingen HC (2008), Predicting a binary outcome using SNPs: a case study on prediction of longevity, Genetic Epidemiology 32(7).
- Lebrec JJ, Putter H, Houwing-Duistermaat JJ & van Houwelingen HC (2008), Influence of genotyping error in linkage mapping for complex traits--an analytic study., BMC Genetics 9: 57.
- Colas F, Meulenbelt I, Houwing-Duistermaat JJ, Slagboom PE & Kok JN (2008), A comparison of two methods for finding groups using heat maps and model based clustering, APPLICATIONS AND INNOVATIONS IN INTELLIGENT SYSTEMS XV: 119-131.
- Colas F, Meulenbelt I, Houwing-Duistermaat JJ, Kloppenburg M, Watt I, van Rooden SA, Visser M, Marinus J, Cannon EO, Bender A, van Hilten JJ, Slagboom PE & Kok JN (2008), A Scenario Implementation in R for SubtypeDiscovery Examplified on Chemoinformatics Data, LEVERAGING APPLICATIONS OF FORMAL METHODS, VERIFICATION AND VALIDATION, PROCEEDINGS 17: 669-683.
- Albers, H.M.; Kurreeman, F.A.S.; Houwing-Duistermaat, J.J.; Brinkman, D.M.C.; Kamphuis, S.S.M.; Girschick, H.J.; Wouters, C.; Rossum, M.A.J. van; Verduijn, W.; Toes, R.E.M.; Huizinga, T.W.J.; Schilham, M.W. & Cate, R. ten (2008), The TRAF1/C5 region is a risk factor for polyarthritis in juvenile idiopathic arthritis., Annals of the Rheumatic Diseases 67(11): 1578-80.
- Lebrec JJP, Putter H, Houwing-Duistermaat JJ & Van Houwelingen HC (2008), Influence of genotyping error in linkage mapping for complex traits - an analytic study, BMC Genetics 9.
- Meulenbelt I, Min JL, Bos S, Riyazi N, Houwing-Duistermaat JJ, van der Wijk HJ, Kroon HM, Nakajima M, Ikegawa S, Uitterlinden AG, van Meurs JBJ, van der Deure WM, Visser TJ, Seymour AB, Lakenberg N, van der Breggen R, Kremer D, van Duijn CM, Kloppenburg M, Loughlin J & Slagboom PE (2008), Identification of DIO2 as a new susceptibility locus for symptomatic osteoarthritis, Human Molecular Genetics 17(12).
- Kurreeman FAS, Rocha D, Houwing-Duistermaat J, Vrijmoet S, Teixeira VH, Migliorini P, Balsa A, Westhovens R, Barrera P, Alves H, Vaz C, Fernandes M, Pascual-Saicedo D, Michou L, Bombardieri S, Radstake T, van Riel P, van de Putte L, Lopes-Vaz A, Prum B, Bardin T, Gut I, Cornelis F, Huizinga TWJ, Petit-Teixeira E & Toes REM (2008), Replication of the tumor necrosis factor receptor-associated factor 1/complement component 5 region as a susceptibility locus for rheumatoid arthritis in a European family-based study, Arthritis and Rheumatism 58(9).
- Ghidey W, Stijnen T, Houwing-Duistermaat JJ, Heijmans BT, Beekman M, Westendorp RGJ, Slagboom PE & van Houwelingen HC (2008), Prediction models for SNP data, Annals of Human Genetics 72.
- Houwing-Duistermaat JJ, Uh HW, van Minkelen R & de Visser MC (2008), A score statistic for genetic association given linkage, Annals of Human Genetics 72.
- Albers, H.; Kurreeman, F.; Houwing-Duistermaat, J.; Brinkman, D.; Kamphuis, S.; Girschick, H.; Wouters, C.; Rossum, M. van; Verduyn, W.; Toes, R.; Huizinga, T.; Schilham, M. & Cate, R. ten (2008), The TRAF1/C5 region is a risk factor for polyarthritis in juvenile idiopathic arthritis, Arthritis and Rheumatism 58(9).
- Oldenburg RA, Kroeze-Jansema KHG, Houwing-Duistermaat JJ, Bayley JP, Dambrot C, van Asperen CJ, van den Ouweland AMW, Bakker B, van Beers EH, Nederlof PM, Vasen H, Hoogerbrugge N, Cornelisse CJ, Meijers-Heijboer H & Devilee P (2008), Genome-wide linkage scan in dutch hereditary non-BRCA 1/2 breast cancer families identifies 9q21-22 as a putative breast cancer susceptibility locus, Genes, Chromosomes and Cancer 47(11).
- Bos SD, Suchiman HED, Kloppenburg M, Houwing-Duistermaat JJ, le Graverand MPH, Seymour AB, Kroon HM, Slagboom PE & Meulenbelt I (2008), Allelic variation at the C-reactive protein gene associates to both hand osteoarthritis severity and serum high sensitive C-reactive protein levels in the GARP study, Annals of the Rheumatic Diseases 67(6).
- Keijser S, Jager MJ, Dogterom-Ballering HCM, Schoonderwoerd DT, de Keizer RJW, Krose CJM, Houwing-Duistermaat JJ, van der Plas MJA, van Dissel JT & Nibbering PH (2008), Lactoferrin Glu561Asp polymorphism is associated with susceptibility to herpes simplex keratitis, Experimental Eye Research 86(1).
- Albers, H.M.; Kurreeman, F.A.S.; Houwing-Duistermaat, J.J.; Brinkman, D.M.C.; Kamphuis, S.S.M.; Girschick, H.J.; Wouters, C.; Rossum, M.A.J. van; Verduijn, W.; Toes, R.E.M.; Huizinga, T.W.J.; Schilham, M.W. & Cate, R. ten (2008), The TRAF1/C5 region is a risk factor for polyarthritis in juvenile idiopathic arthritis, Annals of the Rheumatic Diseases 67(11).
- De Willige SU, De Visser MCH, Vos HL, Houwing-Duistermaat JJ, Rosendaal FR & Bertina RM (2008), Selectin haplotypes and the risk of venous thrombosis: influence of linkage disequilibrium with the factor V Leiden mutation, Journal of Thrombosis and Haemostasis 6(3).
- Thabet M, Van der Helm-Van Mil A, Marques R, Bakker A, White S, Houwing-Duistermaat J, Toes R & Huizinga T (2008), Lower copy number of FC gamma receptor 3B gene is associated with rheumatoid arthritis, Annals of the Rheumatic Diseases 67.
- Supali T, Djuardi Y, Pfarr KM, Wibowo H, Taylor MJ, Hoerauf A, Houwing-Duistermaat JJ, Yazdanbakhsh M & Sartono E (2008), Doxycycline treatment of Brugia malayi-infected persons reduces microfilaremia and adverse reactions after diethylcarbamazine and albendazole treatment, Clinical Infectious Diseases 46(9).
- Callegaro A, van Houwelingen HJC & Houwing-Duistermaat J (2007), Robust testing for genetic linkage taking into account age at onset, Annals of Human Genetics 71: 550-550.
- Uh HW, Mertens BJ, Jan van der Wijk H, Putter H, van Houwelingen HC & Houwing-Duistermaat JJ (2007), Model selection based on logistic regression in a highly correlated candidate gene region., BMC Proceedings 1 Suppl 1: S114.
- Stolk L, Rivadeneira F, Houwing-Duistermaat J, Hofman A, van Meurs JBJ, Pols HAP & Uitterlinden AG (2007), Multi-locus analysis of estrogen pathway polymorphisms and vertebral fracture risk in elderly women: An exercise, Calcified Tissue International 80: S104-S104.
- Kurreeman FAS, Padyukov L, Marques RB, Schrodi SJ, Seddighzadeh M, Stoeken-Rijsbergen G, van der Helm-van Mil AHM, Allaart CF, Verduyn W, Houwing-Duistermaat J, Alfredsson L, Begovich AB, Klareskog L, Huizinga TWJ & Toes REM (2007), A candidate gene approach identifies the TRAF1/C5 region as a risk factor for rheumatoid arthritis, PLoS Medicine 4(9).
- van Minkelen R, de Visser MCH, Houwing-Duistermaat JJ, Vos HL, Bertina RM & Rosendaal FR (2007), Haplotypes of IL1B, IL1RN, IL1R1, and IL1R2 and the risk of venous thrombosis, Arteriosclerosis, Thrombosis, and Vascular Biology 27(6).
- Meulenbelt I, Kloppenburg M, Kroon HM, Houwing-Duistermaat JJ, Garnero P, Hellio-Le Graverand MP, DeGroot J & Slagboom PE (2007), Clusters of biochemical markers are associated with radiographic subtypes of osteoarthritis (OA) in subject with familial OA at multiple sites. The GARP study, Osteoarthritis and Cartilage 15(4).
- Middeldorp A, Jagmohan-Changur S, Helmer Q, van der Klift HM, Tops CMJ, Vasen HFA, Devilee P, Morreau H, Houwing-Duistermaat JJ, Wijnen JT & van Wezel T (2007), A procedure for the detection of linkage with high density SNP arrays in a large pedigree with colorectal cancer, BMC Cancer 7.
- Emonts M, Veenhoven RH, Wiertsema SP, Houwing-Duistermaat JJ, Walraven V, de Groot R, Hermans PWM & Sanders EAM (2007), Genetic polymorphisms in immunoresponse genes TNFA, IL6, IL10, and TLR4 are associated with recurrent acute otitis media, Pediatrics 120(4).
- van de Linde KD, Boor PRC, Houwing-Duistermaat JJ, Crusius BJA, Wilson PJH, Kuipers EJ & de Rooij FWM (2007), CARD15 mutations in Dutch familial and sporadic inflammatory bowel disease and an overview of European studies, European Journal of Gastroenterology and Hepatology 19(6).
- Wesoly J, Hu X, Thabet MM, Chang M, Uh H, Allaart CF, Toes REM, Houwing-Duistermaat JJ, Begovich AB & Huizinga TWJ (2007), The 620W allele is the PTPN22 genetic variant conferring susceptibility to RA in a Dutch population, Rheumatology 46(4).
- Yang Q, Biernacka JM, Chen MH, Houwing-Duistermaat JJ, Bergemann TL, Basu S, Fan R, Liu L, Bourgey M, Clerget-Darpoux F, Lin WY, Elston RC & Cupples LA (2007), Using linkage and association to identify and model genetic ettects: Summary of GAW15 group 4, Genetic Epidemiology 31.
- Emonts M, Wiertsema SP, Veenhoven RH, Houwing-Duistermaat JJ, Walraven V, de Groot R, Hermans PWM & Sanders EAM (2007), The 4G/4G plasminogen activator inhibitor-1 genotype is associated with frequent recurrence of acute otitis media, Pediatrics 120(2).
- Houwing-Duistermaat JJ, Helmer Q, Heijmans BT, Beekman M & Slagboom PE (2007), Selection of informative SNPs for sibling pair linkage analysis from large SNP arrays, Genetic Epidemiology 31(6).
- Callegaro A, van Houwelingen JC & Houwing-Duistermaat JJ (2007), A score statistic for linkage analysis of age at onset data, Genetic Epidemiology 31(6).
- Uh HW, Hartgers FC, Yazdanbakhsh M & Houwing-Duistermaat JJ (2007), Combined analysis of SNP and gene expression data in TLR genes with respect to infection disease in Ghana, Genetic Epidemiology 31(6).
- Houwing-Duistermaat JJ, Callegaro A, Beekman M, Westendorp RGJ, Slagboom E & van Houwelingen JC (2007), A score statistic for linkage analysis of censored outcomes applied to a candidate region at chromosome 4 for human longevity, Genetic Epidemiology 31(5).
- Emonts M, Hazes JMW, Houwing-Duistermaat JJ, de Jongh CE, de Vogel L, Wouters JMGW, Han KH, Laman JD & Dolhain RJEM (2007), Polymorphisms in inflammatory response genes are associated with rheumatoid arthritis, Annals of the Rheumatic Diseases 66.
- Emonts M, de Jongh CE, Houwing-Duistermaat JJ, van Leeuwen WB, de Groot R, Verbrugh HA, Hermans PWM & van Belkum A (2007), Association between nasal carriage of Staphylococcus aureus and the human complement cascade activator serine protease C1 inhibitor (C1INH) valine vs. methionine polymorphism at amino acid position 480, FEMS Immunology and Medical Microbiology 50(3).
- el Galta R, de Willige SU, de Visser MC, Helmer Q, Hsu L & Houwing-Duistermaat JJ (2007), Generalizing Terwilliger's likelihood approach: a new score statistic to test for genetic association, BMC Genetics 8.
- van der Linde K, Boor PPC, Meijssen MAC, Sandkuijl LA, Houwing-Duistermaat JJ, Kuipers EJ, Wilson JHP & de Rooij FWM (2007), Allele-sharing of cytokine genes in familial inflammatory bowel disease, Hepato-Gastroenterology 54(77).
- Mooijaart, S.P.; Kuningas, M.; Westendorp, R.G.J.; Houwing-Duistermaat, J.J.; Slagboom, P.E.; Rensen, P.C.N. & Heemst, D. van (2007), Liver X receptor alpha associates with human life span, The Journals of Gerontology, Series A: Biological Sciences and Medical Sciences 62(4).
- Meulenbelt I, Kloppenburg M, Houwing-Duistermaat JJ, Garnero P, Le Graverand MH, DeGroot J & Slagboom PE (2006), Biochemical markers are associated with radiographic subtypes of osteoarthritis (OA) in subject with familial oa at multiple sites. The GARP study, Annals of the Rheumatic Diseases 65: 589-589.
- Bertoli-Avella AM, Dekker MCJ, Aulchenko YS, Houwing-Duistermaat JJ, Simons E, Testers L, Pardo LM, Rademaker TAM, Snijders PJLM, van Swieten JC, Bonifati V, Heutink P, van Duijn CM & Oostra BA (2006), Evidence for novel loci for late-onset Parkinson's disease in a genetic isolate from the Netherlands, Human Genetics 119(1-2): 51-60.
- Heijmans BT, Beekman M, Houwing-Duistermaat JJ, Cobain MR, Powell J, Blauw GJ, van der Ouderaa F, Westendorp RGJ & Slagboom PE (2006), Lipoprotein particle profiles mark familial and sporadic human longevity, PLoS Medicine 3(12): 2317-2323.
- Botha-Scheepers S, Riyazi N, Kroon HM, Scharloo M, Houwing-Duistermaat JJ, Slagboom E, Rosendaal FR, Breedveld FC & Kloppenburg M (2006), Activity limitations in the lower extremities in patients with osteoarthritis: the modifying effects of illness perceptions and mental health, Osteoarthritis and Cartilage 14(11).
- Min JL, Meulenbelt I, Riyazi N, Kloppenburg M, Houwing-Duistermaat JJ, Seymour AB, van Duijn CM & Slagboom PE (2006), Association of matrilin-3 polymorphisms with spinal disc degeneration and osteoarthritis of the first carpometacarpal joint of the hand, Annals of the Rheumatic Diseases 65(8).
- Oldenburg RA, Kroeze-Jansema K, Meijers-Heijboer H, van Asperen CJ, Hoogerbrugge N, van Leeuwen I, Vasen HFA, Cleton-Jansen AM, Kraan J, Houwing-Duistermaat JJ, Morreau H, Cornelisse CJ & Devilee P (2006), Characterization of familial non-BRCA1/2 breast tumors by loss of heterozygosity and immunophenotyping, Clinical Cancer Research 12(6).
- Rivadeneira F, van Meurs JBJ, Kant J, Zillikens MC, Stolk L, Beck TJ, Arp P, Schuit SCE, Hofman A, Houwing-Duistermaat JJ, van Duijn CM, van Leeuwen JPTM, Pols HAP & Uitterlinden AG (2006), Estrogen receptor beta (ESR2) polymorphisms in interaction with estrogen receptor alpha (ESR1) and insulin-like growth factor I (IGF1) variants influence the risk of fracture in postmenopausal women, Journal of Bone and Mineral Research 21(9).
- Beekman M, Blauw GJ, Houwing-Duistermaat JJ, Brandt BW, Westendorp RGJ & Slagboom PE (2006), Chromosome 4q25, microsomal transfer protein gene, and human longevity: Novel data and a meta-analysis of association studies, Journals of Gerontology, Series A 61(4).
- Meulenbelt I, Kloppenburg M, Kroon HM, Houwing-Duistermaat JJ, Garnero P, Le Graverand MPH, DeGroot J & Slagboom PE (2006), Urinary CTX-II levels are associated with radiographic subtypes of osteoarthritis in hip, knee, hand, and facet joints in subject with familial osteoarthritis at multiple sites: the GARP study, Annals of the Rheumatic Diseases 65(3).
- Geleijns K, Roos A, Houwing-Duistermaat JJ, van Rijs W, Tio-Gillen AP, Laman JD, van Doorn PA & Jacobs BC (2006), Mannose-binding lectin contributes to the severity of Guillain-Barre syndrome.
- de Willige SU, de Visser MCH, Houwing-Duistermaat JJ, Rosendaal FR, Vos HL & Bertina RM (2005), Genetic variation in the fibrinogen gamma gene increases the risk for deep venous thrombosis by reducing plasma fibrinogen gamma ' levels, Blood 106(13).
- Hae-Won Uh, Jeanine J Houwing-Duistermaat & Hein Putter and Hans C van Houwelingen (2005), How to quantify information loss due to phase ambiguity in haplotype case-control studies, BMC Genetics.
- Croes EA, El Galta R, Houwing-Duistermaat JJ, Ferdinand RF, Lopez LS, Rademaker TAM, Dekker MCJ, Oostra BA, Verhulst F & Van Duijn CM (2005), Phenotypic subtypes in attention deficit hyperactivity disorder in an isolated population, European Journal of Epidemiology 20(9).
- Nielsen M, Franken PF, Reinards THCM, Weiss MM, Wagner A, van der Klift H, Kloosterman S, Houwing-Duistermaat JJ, Aalfs CM, Ausems MGEM, Brocker-Vriends AHJT, Garcia EBG, Hoogerbrugge N, Menko FH, Sijmons RH, Verhoef S, Kuipers EJ, Morreau H, Breuning MH, Tops CMJ, Wijnen JT, Vasen HFA, Fodde R & Hes FJ (2005), Multiplicity in polyp count and extracolonic manifestations in 40 Dutch patients with MYH associated polyposis coli (MAP), Journal of Medical Genetics 42(9).
- Hsu L, Yu XS, Houwing-Duistermaat JJ, Uh HW, El Galta R, Lebrec JJP & Tang H (2005), Locally weighted transmission/disequilibrium test for genetic association analysis, BMC Genetics 6: -.
- Houwing-Duistermaat JJ, Uh HW, Lebrec JJP, Putter H & Hsu L (2005), Modeling the effect of an associated single-nucleotide polymorphism in linkage studies, BMC Genetics 6: -.
- El Galta R, Van Duijn CM, Van Houwelingen JC & Houwing-Duistermaat JJ (2005), Score statistic to test for genetic correlation for proband-family design, Annals of Human Genetics 69.
- Geleijns K, Roos A, Houwing-Duistermaat JJ, van Rijs W, Tio-Gillen AP, Laman JD, van Doorn PA & Jacobs BC (2005), Mannose-binding lectin contributes to the severity of Guillain-Barre syndrome, Journal of the Peripheral Nervous System 10.
- Riyazi N, Botha-Scheepers SA, Houwing-Duistermaat JJ, Kroon HM, Rosendaal FR, Slagboom E, Breedveld FC & Kloppenburg M (2005), Why is there a discrepancy between disease and disability in osteoarthritis in the hands?, Annals of the Rheumatic Diseases 64.
- Meulenbelt I, Kloppenburg M, Min JL, Kroon HM, Houwing-Duistermaat JJ, Le Graverand MH, De Groot J & Slagboom E (2005), UCTX-II levels are influenced by radiographic osteoarthritis (OA) in hip, knee, hand, and facet joints in sibling pairs with familial OA at multiple sites. The GARP study, Annals of the Rheumatic Diseases 64.
- Putter H, Houwing-Duistermaat JJ & Nagelkerke NJD (2005), Combining evidence for association from transmission disequilibrium and case-control studies using single-nucleotide polymorphisms, BMC Genetics 6: -.
- Bakker MI, May L, Hatta M, Kwenang A, Klatser PR, Oskam L & Houwing-Duistermaat JJ (2005), Genetic, household and spatial clustering of leprosy on an island in Indonesia: a population-based study, BMC Medical Genetics 6: -.
- Riyazi N, Slagboom E, de Craen AJM, Meulenbelt I, Houwing-Duistermaat JJ, Kroon HM, van Schaardenburg D, Rosendaal FR, Breedveld FC, Huizinga TWJ & Kloppenburg M (2005), Association of the risk of osteoarthritis with high innate production of interleukin-1 beta and low innate production of interleukin-10 ex vivo, upon lipopolysaccharide stimulation, Arthritis and Rheumatism 52(5).
- Min JL, Meulenbelt I, Riyazi N, Kloppenburg M, Houwing-Duistermaat JJ, Seymour AB, Pols HA, van Duijn CM & Slagboom PE (2005), Association of the Frizzled-related protein gene with symptomatic osteoarthritis at multiple sites, Arthritis and Rheumatism 52(4).
- El Galta R, Hsu L & Houwing-Duistermaat JJ (2005), Methods to test for association between a disease and a multi-allelic marker applied to a candidate region, BMC Genetics 6: -.
- Veldhuisen B, Stolk J, Frants RR, van Houwelingen JC & Houwing-Duistermaat JJ (2005), Power considerations for linkage analysis in an extremely selected population: a search for a modifier gene of pulmonary emphysema, Annals of Human Genetics 69: 773-774.
- Houwing-Duistermaat JJ, Putter H & Hsu L (2005), Modelling the effect of an associated single nucleotide polymorphism in affected sibling pair linkage studies, Annals of Human Genetics 69: 767-768.
- Wahyuni S, Houwing-Duistermaat JJ, , Supali T, Yazdanbakhsh M & Sartono E (2004), Clustering of filarial infection in an age-graded study: genetic, household and environmental influences, Parasitology 128.
- Geleijns K, Roos A, Houwing-Duistermaat JJ, van Doorn PA, van Rijs W, Tio-Gillen AP, Laman JD & Jacobs BC (2004), High levels of mannose-binding lectin are related to disease susceptibility and severity in Guillain-Barre syndrome, Journal of Neurology 251.
- Szabo CI, Schutte M, Broeks A, Houwing-Duistermaat JJ, Thorstenson YR, Durocher F, Oldenburg RA, Wasielewski M, Odefrey F, Thompson D, Floore AN, Kraan J, Klijn JGM, van den Ouweland AMW, Wagner TMU, Devilee P, Simard J, van't Veer LJ, Goldgar DE & Meijers-Heijboer H (2004), Are ATM mutations 7271T -> G and IVS10-6T -> G really high-risk breast cancer-susceptibility alleles?, Cancer Research 64(3).
- Geleijns K, Brouwer BA, Jacobs BC, Houwing-Duistermaat JJ, van Duijn CM & van Doorn PA (2004), The occurrence of Guillain-Barre syndrome within families, Neurology 63(9).
- Rivadeneira F, Schuit SCE, Houwing-Duistermaat JJ, Janssen JAM, Hofman A, Beck TJ, Pols HAP, Van Duijn CM & Uitterlinden AG (2004), GENE INTERACTION BETWEEN ESTROGEN RECEPTOR ALPHA AND IGF-I DETERMINES HIP BONE STRENGTH IN ELDERLY MEN, Calcified Tissue International 74: S40-S41.
- Rivadeneira F, Zillikens MC, Houwing-Duistermaat JJ, Beck TJ, Aulchenko Y, Oostra B, Uitterlinden AG, van Duijn CM & Pols HAP (2004), Novel DEXA-based osteoporosis phenotypes for genetic studies.
- Houwing-Duistermaat JJ, Bijkerk C, Hsu L, Stijnen T, Slagboom EP & van Duijn CM (2003), A unified approach to modelling linkage to quantitative and qualitative traits, Annals of Human Genetics 67.
- Kamphuisen PW, Lensen R, Houwing-Duistermaat JJ, Eikenboom JCJ, Harvey M, Bertina RM & Rosendaal FR (2000), Heritability of elevated factor VIII antigen levels in factor V Leiden families with thrombophilia.
- Terhell AJ, Houwing-Duistermaat JJ, Ruiterman Y, Haarbrink M, Abadi K & Yazdanbakhsh M (2000), Clustering of Brugia malayi infection in a community in South-Sulawesi, Indonesia.
- Houwing-Duistermaat JJ, van Houwelingen HC & de Winter JP (2000), Estimation of individual genetic effects from binary observations on relatives applied to a family history of respiratory illnesses and chronic lung disease of newborns, Biometrics 56(3): 808-814.
- van Oordt CWVH, Smits R, Schouten TG, Houwing-Duistermaat JJ, Williamson SLH, Luz A, Khan PM, van der Eb A, Breuer ML & Fodde R (1999), The genetic background modifies the spontaneous and X-ray-induced tumor spectrum in the Apc 1638N mouse model, Genes, Chromosomes and Cancer 24(3): 191-198.
- Meulenbelt I, Bijkerk C, Houwing-Duistermaat JJ, Breedveld FC, van Duijn CM & Slagboom PE (1999), Genetic studies on osteoarthritis., American Journal of Human Genetics 65(4): A435-A435.
- Bijkerk C, Houwing-Duistermaat JJ, Valkenburg HA, Meulenbelt I, Hofman A, Breedveld FC, Pols HAP, van Duijn CM & Slagboom PE (1999), Heritabilities of radiologic osteoarthritis in peripheral joints and of disc degeneration of the spine, Arthritis and Rheumatism 42(8): 1729-1735.
- Slagboom PE, Bijkerk C, Houwing-Duistermaat JJ, Valkenburg HA, Meulenbelt I, Hofman A, Breedveld FC, Pols HAP & van Duijn CM (1999), Heritability and candidate gene studies in Osteoarthritis, Zeitschrift f�r Gerontologie und Geriatrie 32(2): 127-127.
- Kamphuisen PW, Lensen R, Houwing-Duistermaat JJ, Eikenboom JCJ, Harvey M, Bertina RM & Rosendaal FR (1999), Heritability of elevated factor VIII antigen levels in families with thrombophilia, Thrombosis and Haemostasis: 418-419.
- Bijkerk, C.; Houwing-Duistermaat, J.J.; Meulenbelt, I.; Valkenburg, H.A.; Hofman, A.; Breedveld, F.C.; Pols, H.A.P.; Stijnen, T.; Dujin, C.M. van & Slagboom, P.E. (1998), The genetic influence on the occurrence of radiological osteoarthritis., Arthritis and Rheumatism 41(9): S145-S145.
- Kamphuisen PW, Houwing-Duistermaat JJ, van Houwelingen HC, Eikenboom JCJ, Bertina RM & Rosendaal FR (1998), Familial clustering of factor VIII and von Willebrand factor levels, Thrombosis and Haemostasis 79(2): 323-327.
- Houwing-Duistermaat JJ & van Houwelingen HC (1998), Incorporation of family history in logistic regression models, Statistics in Medicine 17(24): 2865-2882.
- Houwing-Duistermaat JJ, van Houwelingen HC & Terhell A (1998), Modelling the cause of dependency with application to filaria infection, Statistics in Medicine 17(24): 2939-2954.
- President
- Boardmember
- Member of Programmee committee