Ferdinand Breedveld
- Naam
- Prof.dr. F.C. Breedveld
- Telefoon
- +31 71 526 2564
- f.c.breedveld@lumc.nl
- ORCID iD
- null
- Faculteit Geneeskunde
- LUMC - Medische Faculteit Leiden
- Stamm, T.A.; Machold, K.P.; Aletaha, D.; Alasti, F.; Lipsky, P.; Pisetsky, D.; Landewe, R.; Heijde, D. van der; Sepriano, A.; Aringer, M.; Boumpas, D.; Burmester, G.; Cutolo, M.; Ebner, W.; Graninger, W.; Huizinga, T.; Schett, G.; Schulze-Koops, H.; Tak, P.P.; Martin-Mola, E.; Breedveld, F. & Smolen, J. (2018), Induction of sustained remission in early inflammatory arthritis with the combination of infliximab plus methotrexate: the DINORA trial, Arthritis Research and Therapy 20.
- Breedveld, F.C.; Kalden, J.R. & Smolen, J.S. (2016), Advances in targeted therapy, Rheumatology 55: 1-2.
- Winthrop, K.L.; Strand, V.; Heijde, D. van der; Mease, P.; Crow, M.K.; Weinblatt, M.; Bathon, J.; Buch, M.H.; Burmester, G.R.; Dougados, M.; Kay, J.; Mariette, X.; Breedveld, F.C.; Kalden, J.R.; Smolen, J.S. & Furst, D.E. (2016), The unmet need in rheumatology: reports from the Targeted Therapies meeting 2016, Clinical and Experimental Rheumatology 34(4): S69-S76.
- Smolen, J.S.; Basset, S.C.; Boers, M.; Breedveld, F.; Edwards, C.J.; Kvien, T.K.; Miossec, P.; Sokka-Isler, T.; Vollenhoven, R.F. van; Abadie, E.C.; Bruyere, O.; Cooper, C.; Makinen, H.; Thomas, T.; Tugwell, P.; Reginster, J.Y. & European Soc Clinical Economic (2016), Clinical trials of new drugs for the treatment of rheumatoid arthritis: focus on early disease, Annals of the Rheumatic Diseases 75(7): 1268-1271.
- Stoffer, M.A.; Schoels, M.M.; Smolen, J.S.; Aletaha, D.; Breedveld, F.C.; Burmester, G.; Bykerk, V.; Dougados, M.; Emery, P.; Haraoui, B.; Gomez-Reino, J.; Kvien, T.K.; Nash, P.; Navarro-Compan, V.; Scholte-Voshaar, M.; Vollenhoven, R. van; Heijde, D. van der & Stamm, T.A. (2016), y Evidence for treating rheumatoid arthritis to target: results of a systematic literature search update, Annals of the Rheumatic Diseases 75(1): 16-22.
- Smolen, J.S.; Breedveld, F.C.; Burmester, G.R.; Bykerk, V.; Dougados, M.; Emery, P.; Kvien, T.K.; Navarro-Compan, M.V.; Oliver, S.; Schoels, M.; Scholte-Voshaar, M.; Stamm, T.; Stoffer, M.; Takeuchi, T.; Aletaha, D.; Andreu, J.L.; Aringer, M.; Bergman, M.; Betteridge, N.; Bijlsma, H.; Burkhardt, H.; Cardiel, M.; Combe, B.; Durez, P.; Fonseca, J.E.; Gibofsky, A.; Gomez-Reino, J.J.; Graninger, W.; Hannonen, P.; Haraoui, B.; Kouloumas, M.; Landewe, R.; Martin-Mola, E.; Nash, P.; Ostergaard, M.; Ostor, A.; Richards, P.; Sokka-Isler, T.; Thorne, C.; Tzioufas, A.G.; Vollenhoven, R. van; Wit, M. de & Heijde, D. van der (2016), Treating rheumatoid arthritis to target: 2014 update of the recommendations of an international task force, Annals of the Rheumatic Diseases 75(1): 3-15.
- Smolen, J.S.; Landewe, R.; Breedveld, F.C.; Buch, M.; Burmester, G.; Dougados, M.; Emery, P.; Gaujoux-Viala, C.; Gossec, L.; Nam, J.; Ramiro, S.; Winthrop, K.; Wit, M. de; Aletaha, D.; Betteridge, N.; Bijlsma, J.W.J.; Boers, M.; Buttgereit, F.; Combe, B.; Cutolo, M.; Damjanov, N.; Hazes, J.M.W.; Kouloumas, M.; Kvien, T.K.; Mariette, X.; Pavelka, K.; Riel, P.L.C.M. van; Rubbert-Roth, A.; Scholte-Voshaar, M.; Scott, D.L.; Sokka-Isler, T.; Wong, J.B. & Heijde, D. van der (2014), EULAR recommendations for the management of rheumatoid arthritis with synthetic and biological disease-modifying antirheumatic drugs: 2013 update, Annals of the Rheumatic Diseases 73(3): 492-509.
- Keystone, E.C.; Breedveld, F.C.; Heijde, D. van der; Landewe, R.; Florentinus, S.; Arulmani, U.; Liu, S.F.; Kupper, H. & Kavanaugh, A. (2014), Longterm Effect of Delaying Combination Therapy with Tumor Necrosis Factor Inhibitor in Patients with Aggressive Early Rheumatoid Arthritis: 10-year Efficacy and Safety of Adalimumab from the Randomized Controlled PREMIER Trial with Open-label Extension, Journal of Rheumatology 41(1): 5-14.
- Keystone, E.; Breedveld, F.; Heijde, D. van der; Vollenhoven, R. van; Florentinus, S.; Faccin, F.; Liu, S.F.; Kupper, H. & Kavanaugh, A. (2013), Achieving Comprehensive Disease Control in Long-Standing or Early Rheumatoid Arthritis Patients Treated with Adalimumab Plus Methotrexate versus Methotrexate Alone.
- Keystone, E.; Heijde, D. van der; Landewe, R.; Breedveld, F.; Liu, S.F. & Mozaffarian, N. (2013), Analysis of Integrated Radiographic Data for Two Longterm, Open-Label Extension Studies of Adalimumab.
- Furst, D.E.; Keystone, E.C.; So, A.K.; Braun, J.; Breedveld, F.C.; Burmester, G.R.; Benedetti, F. de; Dorner, T.; Emery, P.; Fleischmann, R.; Gibofsky, A.; Kalden, J.R.; Kavanaugh, A.; Kirkham, B.; Mease, P.; Rubbert-Roth, A.; Sieper, J.; Singer, N.G.; Smolen, J.S.; Riel, P.L.C.M. van; Weisman, M.H. & Winthrop, K.L. (2013), Updated consensus statement on biological agents for the treatment of rheumatic diseases, 2012, Annals of the Rheumatic Diseases 72: 2-34.
- Breedveld, F.C.; Kalden, J.R. & Smolen, J.S. (2013), Advances in targeted therapies XIV, Annals of the Rheumatic Diseases 72: 1-1.
- Schoels, M.M.; Heijde, D. van der; Breedveld, F.C.; Burmester, G.R.; Dougados, M.; Emery, P.; Ferraccioli, G.; Gabay, C.; Gibofsky, A.; Gomez-Reino, J.J.; Jones, G.; Kvien, T.K.; Murikama, M.M.; Nishimoto, N. & Smolen, J.S. (2013), Blocking the effects of interleukin-6 in rheumatoid arthritis and other inflammatory rheumatic diseases: systematic literature review and meta-analysis informing a consensus statement, Annals of the Rheumatic Diseases 72(4): 583-589.
- Smolen, J.S.; Schoels, M.M.; Nishimoto, N.; Breedveld, F.C.; Burmester, G.R.; Dougados, M.; Emery, P.; Ferraccioli, G.; Gabay, C.; Gibofsky, A.; Gomez-Reino, J.J.; Jones, G.; Kvien, T.K.; Murakami, M.; Betteridge, N.; Bingham, C.O.; Bykerk, V.; Choy, E.H.; Combe, B.; Cutolo, M.; Graninger, W.; Lanas, A.; Martin-Mola, E.; Montecucco, C.; Ostergaard, M.; Pavelka, K.; Rubbert-Roth, A.; Sattar, N.; Scholte-Voshaar, M.; Tanaka, Y.; Trauner, M.; Valentini, G.; Winthrop, K.L.; Wit, M. de & Heijde, D. van der (2013), Consensus statement on blocking the effects of interleukin-6 and in particular by interleukin-6 receptor inhibition in rheumatoid arthritis and other inflammatory conditions, Annals of the Rheumatic Diseases 72(4): 482-492.
- Keystone, E.C.; Breedveld, F.C.; Heijde, D. van der; Landewe, R.; Florentinus, S.; Arulmani, U.; Liu, S.F.; Kupper, H. & Kavanaugh, A. (2013), Long-Term Impact of Delaying Combination Therapy With Adalimumab Plus Methotrexate By 2 Years in Patients With Early Rheumatoid Arthritis: Final 10-Year Results of the Premier Trial, Arthritis and Rheumatism 65: S595-S595.
- Keystone, E.; Breedveld, F.; Kupper, H.; Liu, S.F. & Florentinns, S. (2013), Longterm Use of Adalimumab as Monotherapy Following Attainment of Low Disease Activity with Adalimumab plus Methotrexate, Journal of Rheumatology 40(6): 967-968.
- Breedveld, F.C.; Kalden, J.R. & Smolen, J.S. (2012), Advances in targeted therapies XIII, Annals of the Rheumatic Diseases 71: 1-1.
- Furst, D.E.; Keystone, E.C.; Braun, J.; Breedveld, F.C.; Burmester, G.R.; Benedetti, F. de; Dorner, T.; Emery, P.; Fleischmann, R.; Gibofsky, A.; Kalden, J.R.; Kavanaugh, A.; Kirkham, B.; Mease, P.; Sieper, J.; Singer, N.G.; Smolen, J.S.; Riel, P.L.C.M. van; Weisman, M.H. & Winthrop, K. (2012), Updated consensus statement on biological agents for the treatment of rheumatic diseases, 2011, Annals of the Rheumatic Diseases 71: 2-45.
- Gossec, L.; Smolen, J.S.; Gaujoux-Viala, C.; Ash, Z.; Marzo-Ortega, H.; Heijde, D. van der; FitzGerald, O.; Aletaha, D.; Balint, P.; Boumpas, D.; Braun, J.; Breedveld, F.C.; Burmester, G.; Canete, J.D.; Wit, M. de; Dagfinrud, H.; Vlam, K. de; Dougados, M.; Helliwell, P.; Kavanaugh, A.; Kvien, T.K.; Landewe, R.; Luger, T.; Maccarone, M.; McGonagle, D.; McHugh, N.; McInnes, I.B.; Ritchlin, C.; Sieper, J.; Tak, P.P.; Valesini, G.; Vencovsky, J.; Winthrop, K.L.; Zink, A. & Emery, P. (2012), European League Against Rheumatism recommendations for the management of psoriatic arthritis with pharmacological therapies, Annals of the Rheumatic Diseases 71(1): 4-12.
- Breedveld, F.; Keystone, E.; Heijde, D. van der; Landewe, R.; Smolen, J.S.; Guerette, B.; McIlraith, M.; Kupper, H.; Liu, S.F. & Kavanaugh, A. (2012), INITIAL COMBINATION THERAPY WITH ADALIMUMAB PLUS METHOTREXATE LEADS TO BETTER LONG-TERM OUTCOMES THAN WITH EITHER MONOTHERAPY IN PATIENTS WITH EARLY RHEUMATOID ARTHRITIS: 8-YEAR RESULTS OF AN OPEN-LABEL EXTENSION OF A PHASE 3 TRIAL, Rheumatology 51: 118-119.
- Keystone, E.C.; Breedveld, F.C.; Kupper, H.; Liu, S.F. & Florentinus, S. (2012), Long-Term Use of Adalimumab As Monotherapy Following Attainment of Low Disease Activity with Adalimumab Plus Methotrexate, Arthritis and Rheumatism 64(10): S559-S560.
- Heijde, D. van der; Landewe, R.; Keystone, E.C.; Breedveld, F.C.; Liu, S.F. & Mozaffarian, N. (2012), Analysis of Integrated Radiographic Data for Two Long-Term, Open-Label Extension Studies of Adalimumab., Arthritis and Rheumatism 64(10): S439-S440.
- Keystone, E.C.; Breedveld, F.C.; Heijde, D. van der; Vollenhoven, R.F. van; Florentinus, S.; Faccin, F.; Liu, S.F.; Kupper, H. & Kavanaugh, A. (2012), Achieving Comprehensive Disease Control in Long-Standing or Early Rheumatoid Arthritis Patients Treated with Adalimumab Plus Methotrexate Versus Methotrexate Alone, Arthritis and Rheumatism 64(10): S559-S559.
- Buch, M.H.; Smolen, J.S.; Betteridge, N.; Breedveld, F.C.; Burmester, G.; Dorner, T.; Ferraccioli, G.; Gottenberg, J.E.; Isaacs, J.; Kvien, T.K.; Mariette, X.; Martin-Mola, E.; Pavelka, K.; Tak, P.P.; Heijde, D. van der; Vollenhoven, R.F. van; Emery, P. & Rituximab Consensus Expert Comm (2011), Updated consensus statement on the use of rituximab in patients with rheumatoid arthritis, Annals of the Rheumatic Diseases 70(6): 909-920.
- Breedveld, F.C. & Combe, B. (2011), Understanding emerging treatment paradigms in rheumatoid arthritis, Arthritis Research and Therapy 13.
- Burmester, G.; Lanas, A.; Biasucci, L.; Hermann, M.; Lohmander, S.; Olivieri, I.; Scarpignato, C.; Smolen, J.; Hawkey, C.; Bajkowski, A.; Berenbaum, F.; Breedveld, F.; Dieleman, P.; Dougados, M.; MacDonald, T.; Mola, E.M.; Mets, T.; Noortgate, N. van den & Stoevelaar, H. (2011), The appropriate use of non-steroidal anti-inflammatory drugs in rheumatic disease: opinions of a multidisciplinary European expert panel, Annals of the Rheumatic Diseases 70(5): 818-822.
- Genovese, M.C.; Breedveld, F.C.; Emery, P.; Cohen, S.B.; Keystone, E.; Matteson, E.L.; Burke, L.; Chai, A.; Reiss, W.; Sweetser, M. & Shaw, T. (2011), SAFETY OF SUBSEQUENT BIOLOGIC THERAPY IN RA PATIENTS WHO DISCONTINUED RITUXIMAB, Rheumatology 50: 126-126.
- Nash, P.; Breedveld, F.C.; Robertson, D.; Foehl, J.; Ferdousi, T.; Freundlich, B. & Koenig, A. (2011), ETANERCEPT PLUS METHOTREXATE COMBINATION THERAPY IS EFFICACIOUS IN MODERATE AS WELL AS SEVERE EARLY RHEUMATOID ARTHRITIS, Rheumatology 50: ii3ii3.
- Miossec, P.; Verweij, C.L.; Klareskog, L.; Pitzalis, C.; Barton, A.; Lekkerkerker, F.; Reiter, S.; Laslop, A.; Breedveld, F.; Abadie, E.; Flamion, B.; Dere, W.; Mpofu, S.; Goel, N.; Ethgen, D.; Mitlak, B.; Ormarsdottir, S.; Rao, R.; Tsouderos, Y.; Reginster, J.Y. & GREES (2011), Biomarkers and personalised medicine in rheumatoid arthritis: a proposal for interactions between academia, industry and regulatory bodies, Annals of the Rheumatic Diseases 70(10): 1713-1718.
- Genovese, M.; Cividino, A.; Keystone, E.; Breedveld, F.; Emery, P.; Cohen, S.; Matteson, E.; Burke, L.; Chai, A.; Reiss, W.; Sweetser, M. & Shaw, T. (2011), Assessing the Rate of Serious Infections in Rheumatoid Arthritis (RA) Patients who Receive Other Biologic Therapies after Discontinuing Rituximab (RTX), Journal of Rheumatology 38(6): 1165-1165.
- Breedveld, F.C.; Kalden, J.R. & Smolen, J.S. (2011), Advances in targeted therapies XII, Annals of the Rheumatic Diseases 70: I1I1.
- Smolen, J.S.; Boers, M.; Abadie, E.C.; Breedveld, F.C.; Emery, P.; Bardin, T.; Goel, N.; Ethgen, D.J.; Avouac, B.P.; Dere, W.H.; Durez, P.; Matucci-Cerinic, M.; Flamion, B.; Laslop, A.; Lekkerkerker, F.J.; Miossec, P.; Mitlak, B.H.; Ormarsdottir, S.; Paolozzi, L.; Rao, R.; Reiter, S.; Tsouderos, Y.; Reginster, J.Y. & GREES (2011), Recommendations for an update of 2003 European regulatory requirements for registration of drugs to be used in the treatment of RA, Current Medical Research and Opinion 27(2): 315-325.
- Smolen, J.S.; Boers, M.; Abadie, E.C.; Breedveld, F.C.; Emery, P.; Bardin, T.; Goel, N.; Ethgen, D.J.; Avouac, B.P.; Durez, P.; Flamion, B.; Laslop, A.; Miossec, P.; Reiter, S.; Reginster, J.Y. & Task Force Grp Respect Ethics & Ex (2011), Updating the 2003 European regulatory requirements for registering disease-modifying drugs to be used in the treatment of rheumatoid arthritis., Rheumatology.
- Goekoop-Ruiterman, Y.P.M.; Vries-Bouwstra, J.K. de; Kerstens, P.J.S.M.; Nielen, M.M.J.; Vos, K.; Schaardenburg, D. van; Speyer, I.; Seys, P.E.H.; Breedveld, F.C.; Allaart, C.F. & Dijkmans, B.A.C. (2010), DAS-driven therapy versus routine care in patients with recent-onset active rheumatoid arthritis, Annals of the Rheumatic Diseases 69(1): 65-69.
- Furst, D.E.; Keystone, E.C.; Braun, J.; Breedveld, F.C.; Burmester, G.R.; Benedetti, F. de; Dorner, T.; Emery, P.; Fleischmann, R.; Gibofsky, A.; Kalden, J.R.; Kavanaugh, A.; Kirkham, B.; Mease, P.; Sieper, J.; Singer, N.G.; Smolen, J.S.; Riel, P.L.C.M. van; Weisman, M.H. & Winthrop, K. (2010), Updated consensus statement on biological agents for the treatment of rheumatic diseases, 2009, Annals of the Rheumatic Diseases 69: 2-29.
- Coombs, J.H.; Bloom, B.J.; Breedveld, F.C.; Fletcher, M.P.; Gruben, D.; Kremer, J.M.; Burgos-Vargas, R.; Wilkinson, B.; Zerbini, C.A.F. & Zwillich, S.H. (2010), Improved pain, physical functioning and health status in patients with rheumatoid arthritis treated with CP-690,550, an orally active Janus kinase (JAK) inhibitor: results from a randomised, double-blind, placebo-controlled trial, Annals of the Rheumatic Diseases 69(2): 413-416.
- Smolen, J.S.; Landewe, R.; Breedveld, F.C.; Dougados, M.; Emery, P.; Gaujoux-Viala, C.; Gorter, S.; Knevel, R.; Nam, J.; Schoels, M.; Aletaha, D.; Buch, M.; Gossec, L.; Huizinga, T.; Bijlsma, J.W.J.W.; Burmester, G.; Combe, B.; Cutolo, M.; Gabay, C.; Gomez-Reino, J.; Kouloumas, M.; Kvien, T.K.; Martin-Mola, E.; McInnes, I.; Pavelka, K.; Riel, P. van; Scholte, M.; Scott, D.L.; Sokka, T.; Valesini, G.; Vollenhoven, R. van; Winthrop, K.L.; Wong, J.; Zink, A. & Heijde, D. van der (2010), EULAR recommendations for the management of rheumatoid arthritis with synthetic and biological disease-modifying antirheumatic drugs, Annals of the Rheumatic Diseases 69(6): 964-975.
- Schoels, M.; Knevel, R.; Aletaha, D.; Bijlsma, J.W.J.; Breedveld, F.C.; Boumpas, D.T.; Burmester, G.; Combe, B.; Cutolo, M.; Dougados, M.; Emery, P.; Heijde, D. van der; Huizinga, T.W.J.; Kalden, J.; Keystone, E.C.; Kvien, T.K.; Martin-Mola, E.; Montecucco, C.; Wit, M. de & Smolen, J.S. (2010), Evidence for treating rheumatoid arthritis to target: results of a systematic literature search, Annals of the Rheumatic Diseases 69(4): 638-643.
- Machold, K.P.; Landewe, R.; Smolen, J.S.; Stamm, T.A.; Heijde, D.M. van der; Verpoort, K.N.; Brickmann, K.; Vazquez-Mellado, J.; Karateev, D.E.; Breedveld, F.C.; Emery, P. & Huizinga, T.W.J. (2010), The Stop Arthritis Very Early (SAVE) trial, an international multicentre, randomised, double-blind, placebo-controlled trial on glucocorticoids in very early arthritis, Annals of the Rheumatic Diseases 69(3): 495-502.
- Heijde, D. van der; Breedveld, F.C.; Kavanaugh, A.; Keystone, E.C.; Landewe, R.; Patra, K. & Pangan, A.L. (2010), Disease Activity, Physical Function, and Radiographic Progression After Longterm Therapy with Adalimumab Plus Methotrexate: 5-Year Results of PREMIER, Journal of Rheumatology 37(11): 2237-2246.
- Landewe, R.B.M.; Houbiers, J.G.A.; Bosch, F. van den; in't Hout, J.; Verschueren, P.C.P.M.; Meijerink, J.H.; Hoogen, F.H.J. van den; Masek, B.A.; Bruyn, G.A.W.; Wouters, J.M.G.W.; Voskuyl, A.E.; Laar, J.M. van; Bijlsma, J.J.W.; Heijde, D.M.F.M. van der; Breedveld, F.C.; Putte, L.B.A. van de; Miltenburg, A.M.M. & Keyser, F. de (2010), Intranasal administration of recombinant human cartilage glycoprotein-39 as a treatment for rheumatoid arthritis: a phase II, multicentre, double-blind, randomised, placebo-controlled, parallel-group, dose-finding trial, Annals of the Rheumatic Diseases 69(9): 1655-1659.
- Smolen, J.S.; Aletaha, D.; Bijlsma, J.W.J.; Breedveld, F.C.; Boumpas, D.; Burmester, G.; Combe, B.; Cutolo, M.; Wit, M. de; Dougados, M.; Emery, P.; Gibofsky, A.; Gomez-Reino, J.J.; Haraoui, B.; Kalden, J.; Keystone, E.C.; Kvien, T.K.; McInnes, I.; Martin-Mola, E.; Montecucco, C.; Schoels, M.; Heijde, D. van der & T2T Expert Comm (2010), Treating rheumatoid arthritis to target: recommendations of an international task force, Annals of the Rheumatic Diseases 69(4): 631-637.
- Emery, P.; Breedveld, F.; Heijde, D. van der; Ferraccioli, G.; Dougados, M.; Robertson, D.; Pedersen, R.; Koenig, A.S.; Freundlich, B. & Combination Methotrexate Etanercep (2010), Two-Year Clinical and Radiographic Results With Combination Etanercept-Methotrexate Therapy Versus Monotherapy in Early Rheumatoid Arthritis, Arthritis and Rheumatism 62(3): 674-682.
- Breedveld, F.C.; Kalden, J.R. & Smolen, J.S. (2010), Advances in targeted therapies XI., Annals of the Rheumatic Diseases 69 Suppl 1: i1.
- Genovese, M.C.; Breedveld, F.C.; Emery, P.; Cohen, S.B.; Keystone, E.C.; Matteson, E.L.; Burke, L.S.; Chai, A.; Reiss, W.G.; Sweetser, M.T. & Shaw, T.M. (2010), AN ASSESSMENT OF THE SERIOUS INFECTION RATE IN RITUXIMAB-TREATED RHEUMATOID ARTHRITIS (RA) PATIENTS WHO SUBSEQUENTLY RECEIVED OTHER BIOLOGIC THERAPIES: A FOLLOW-UP FROM RITUXIMAB CLINICAL TRIALS, Rheumatology 49: I4I4.
- Risselada, A.; Tekstra, J.; Teng, Y.K.; Welsing, P.M.J.; Breedveld, F.; Laar, J.M. van & Bijlsma, J.W.J. (2010), Costs of rituximab maintenance treatment in patients with refractory rheumatoid arthritis, Annals of the Rheumatic Diseases 69(10): 1891U1982.
- Schoels, M.; Aletaha, D.; Smolen, J.S.; Bijlsma, J.W.J.; Burmester, G.; Breedveld, F.C.; Cutolo, M.; Combe, B.; Dougados, M.; Emery, P.; Kalden, J.; Keystone, E.C.; Kvien, T.K.; Martin-Mola, E.; Montecucco, C. & Wit, M. de (2010), Follow-up standards and treatment targets in rheumatoid arthritis: results of a questionnaire at the EULAR 2008, Annals of the Rheumatic Diseases 69(3): 575-578.
- Kremer JM, Bloom BJ, Breedveld FC, Coombs JH, Fletcher MP, Gruben D, Krishnaswami S, Burgos-Vargas R, Wilkinson B, Zerbini CAF & Zwillich SH (2009), The Safety and Efficacy of a JAK Inhibitor in Patients With Active Rheumatoid Arthritis Results of a Double-Blind, Placebo-Controlled Phase IIa Trial of Three Dosage Levels of CP-690,550 Versus Placebo, Arthritis and Rheumatism 60(7): 1895-1905.
- Genovese MC, Breedveld FC, Emery P, Cohen SB, Keystone E, Matteson E, Baptiste Y, Burke L, Reiss W & Sweetser M (2009), SAFETY OF OTHER BIOLOGIC THERAPIES FOLLOWING RITUXIMAB TREATMENT IN RA PATIENTS, Rheumatology 48: I90I91.
- Khraishi M, Genovese MC & Breedveld F (2009), Safety of Other Biologic Therapies Following Rituximab Treatment in RA Patients, Journal of Rheumatology 36(11): 2598-2599.
- Genovese MC, Breedveld FC, Emery P, Cohen S, Keystone E, Matteson EL, Baptiste Y, Chai A, Burke L, Reiss W, Sweetser M & Shaw TM (2009), Safety of biological therapies following rituximab treatment in rheumatoid arthritis patients, Annals of the Rheumatic Diseases 68(12): 1894-1897.
- Teng, Y.K.O.; Tekstra, J.; Breedveld, F.C.; Lafeber, F.; Bijlsma, J.W.J. & Laar, J.M. van (2009), Rituximab fixed retreatment versus on-demand retreatment in refractory rheumatoid arthritis: comparison of two B cell depleting treatment strategies, Annals of the Rheumatic Diseases 68(6): 1075-1077.
- Aletaha D, Funovits J, Breedveld FC, Sharp J, Segurado O & Smolen JS (2009), Rheumatoid Arthritis Joint Progression in Sustained Remission Is Determined by Disease Activity Levels Preceding the Period of Radiographic Assessment, Arthritis and Rheumatism 60(5): 1242-1249.
- Gilworth G, Emery P, Gossec L, Vlieland TPMV, Breedveld FC, Hueber AJ, Schett G & Tennant A (2009), Adaptation and cross-cultural validation of the rheumatoid arthritis work instability scale (RA-WIS), Annals of the Rheumatic Diseases 68(11): 1686-1690.
- van den Hout WB, Goekoop-Ruiterman YPM, Allaart CF, de Vries-Bouwstra JK, Hazes JMM, Kerstens PJSM, van Zeben D, Hulsmans HMJ, de Jonge-Bok JM & de Sonnaville PBJ (2009), Cost-Utility Analysis of Treatment Strategies in Patients With Recent-Onset Rheumatoid Arthritis, Arthritis and Rheumatism 61(3): 291-299.
- van der Kooij SM, le Cessie S, Goekoop-Ruiterman YPM, de Vries-Bouwstra JK, van Zeben D, Kerstens PJSM, Hazes JMW, van Schaardenburg D, Breedveld FC & Dijkmans BAC (2009), Clinical and radiological efficacy of initial vs delayed treatment with infliximab plus methotrexate in patients with early rheumatoid arthritis, Annals of the Rheumatic Diseases 68(7): 1153-1158.
- Guler-Yuksel M, Allaart CF, Goekoop-Ruiterman YPM, de Vries-Bouwstra JK, van Groenendael JHLM, Mallee C, de Bois MHW, Breedveld FC, Dijkmans BAC & Lems WF (2009), Changes in hand and generalised bone mineral density in patients with recent-onset rheumatoid arthritis, Annals of the Rheumatic Diseases 68(3): 330-336.
- Botha-Scheepers S, Riyazi N, Watt I, Rosendaal FR, Slagboom E, Bellamy N, Breedveld FC & Kloppenburg M (2009), Progression of hand osteoarthritis over 2 years: a clinical and radiological follow-up study, Annals of the Rheumatic Diseases 68(8): 1260-1264.
- Emmer BJ, van der Bijl AE, Huizinga TW, Breedveld FC, Steens SC, Th Bosma GP, van Buchem MA & van der Grond J (2009), Brain involvement in rheumatoid arthritis: a magnetic resonance spectroscopy study., Arthritis and Rheumatism 60(11): 3190-5.
- Bijl, A.E. van der; Teng, Y.K.O.; Oosterhout, M. van; Breedveld, F.C.; Allaart, C.F. & Huizinga, T.W.J. (2009), Efficacy of Intraarticular Infliximab in Patients With Chronic or Recurrent Gonarthritis: A Clinical Randomized Trial, Arthritis and Rheumatism 61(7): 974-978.
- van der Kooij SM, Goekoop-Ruiterman YPM, de Vries-Bouwstra JK, Guler-Yuksel M, Zwinderman AH, Kerstens PJSM, van der Lubbe PAHM, de Beus WM, Grillet BAM, Ronday HK, Huizinga TWJ, Breedveld FC, Dijkmans BAC & Allaart CF (2009), Drug-free remission, functioning and radiographic damage after 4 years of response-driven treatment in patients with recent-onset rheumatoid arthritis, Annals of the Rheumatic Diseases 68(6): 914-921.
- Emmer BJ, van der Bijl AE, Huizinga TWJ, Breedveld FC, Steens SCA, Bosma GPT, van Buchem MA & van der Grond J (2009), Brain Involvement in Rheumatoid Arthritis A Magnetic Resonance Spectroscopy Study, Arthritis and Rheumatism 60(11): 3190-3195.
- van der Kooij SM, de Vries-Bouwstra JK, Goekoop-Ruiterman YPM, Ewals JAPM, Han KH, Hazes JMW, Kerstens PJSM, Peeters AJ, van Zeben D & Breedveld FC (2009), Patient-Reported Outcomes in a Randomized Trial Comparing Four Different Treatment Strategies in Recent-Onset Rheumatoid Arthritis, Arthritis and Rheumatism 61(1): 4-12.
- Botha-Scheepers S, Riyazi N, Watt I, Rosendaal FR, Slagboom E, Bellamy N, Breedveld FC & Kloppenburg M (2009), Progression of hand osteoarthritis over 2 years: a clinical and radiological follow-up study., Annals of the Rheumatic Diseases 68(8): 1260-4.
- van der Kooij SM, le Cessie S, Goekoop-Ruiterman YP, de Vries-Bouwstra JK, van Zeben D, Kerstens PJ, Hazes JM, van Schaardenburg D, Breedveld FC, Dijkmans BA & Allaart CF (2009), Clinical and radiological efficacy of initial vs delayed treatment with infliximab plus methotrexate in patients with early rheumatoid arthritis., Annals of the Rheumatic Diseases 68(7): 1153-8.
- De Boer IG, Peeters AJ, Ronday HK, Mertens BJA, Breedveld FC & Vlieland TPMV (2008), The usage of functional wrist orthoses in patients with rheumatoid arthritis, Disability and Rehabilitation 30(4).
- Botha-Scheepers S, Dougados M, Ravaud P, Le Graverand MPH, Watt I, Breedveld FC & Kloppenburg M (2008), Effect of medial tibial plateau alignment on serial radiographs on the capacity to predict progression of knee osteoarthritis, Osteoarthritis and Cartilage 16(2).
- Genovese M, Van Vollenhoven R, Breedveld F, Emery P, Moreland L, Keystone E, Matteson E, Baptiste Y, Burke L, Reiss W, Sweetser M & Shaw T (2008), Safety of TNF inhibitors (TNF-is) and non-biologic DMARDs in rheumatoid arthritis (RA) patients (pts) previously treated with Rituximab (RTX), Scandinavian Journal of Rheumatology 37.
- de Jong Z, Munneke M, Vilim V, Zwinderman AH, Kroon HM, Ronday HK, Lems WF, Dijkmans BA, Breedveld FC, Vliet Vlieland TP, Hazes JM & Degroot J (2008), Value of serum cartilage oligomeric matrix protein as a prognostic marker of large-joint damage in rheumatoid arthritis--data from the RAPIT study., Rheumatology 47(6): 868-71.
- de Boer IG, Peeters AJ, Ronday HK, Mertens BJ, Breedveld FC & Vliet Vlieland TP (2008), The usage of functional wrist orthoses in patients with rheumatoid arthritis., Disability and Rehabilitation 30(4): 286-95.
- Emery P, Breedveld F, Hall S, Durez P, Pedersen R, Robertson D, Koenig AS & Freundlich B (2008), Remission rates in subjects with active early rheumatoid arthritis - 1 year results of the comet trial, Rheumatology 47.
- Emery P, Genovese MC, Breedveld F, Moreland L, Keystone E, Matteson EL, Baptiste Y, Reiss W, Sweetser M & Shaw T (2008), Safety of tnf inhibitors and non-biologic DMARDs in rheumatoid arthritis patients previously treated with rituximab, Rheumatology 47.
- van der Kooij SM, Allaart CF, Dijkmans BAC & Breedveld FC (2008), Innovative treatment strategies for patients with rheumatoid arthritis, Current Opinion in Rheumatology 20(3).
- Guler-Yuksel M, Bijsterbosch J, Goekoop-Ruiterman YPM, de Vries-Bouwstra JK, Hulsmans HMJ, de Beus WM, Han KH, Breedveld FC, Dijkmans BAC, Allaart CF & Lems WF (2008), Changes in bone mineral density in patients with recent onset, active rheumatoid arthritis, Annals of the Rheumatic Diseases 67(6).
- de Vries-Bouwstra JK, Goekoop-Ruiterman YPM, Verpoort KN, Schreuder GMT, Ewals JAPM, Terwiel JP, Ronday HK, Kerstens PJSM, Toes REM, de Vries RRP, Breedveld FC, Dijkmans BAC, Huizinga TWJ & Allaart CF (2008), Progression of joint damage in early rheumatoid arthritis, Arthritis and Rheumatism 58(5).
- de Jong Z, Munneke M, Vilim V, Zwinderman AH, Kroon HM, Ronday HK, Lems WF, Dijkmans BAC, Breedveld FC, Vlieland TPMV, Hazes JMW & DeGroot J (2008), Value of serum cartilage oligomeric matrix protein as a prognostic marker of large-joint damage in rheumatoid arthritis - data from the RAPIT study, Rheumatology 47(6).
- Riyazi N, Rosendaal FR, Slagboom E, Kroon HM, Breedveld FC & Kloppenburg M (2008), Risk factors in familial osteoarthritis: the GARP sibling study, Osteoarthritis and Cartilage 16(6).
- van der Bijl AE, Breedveld FC, Antoni CE, Kalden JR, Kary S, Burmester GR, Beckmann C, Unnebrink K & Kupper H (2008), An open-label pilot study of the effectiveness of adalimumab in patients with rheumatoid arthritis and previous infliximab treatment: relationship to reasons for failure and anti-infliximab antibody status, Clinical Rheumatology 27(8).
- Botha-Scheepers S, Watt I, Slagboom E, de Craen AJM, Meulenbelt I, Rosendaal FR, Breedveld FC, Huizinga TWJ & Kloppenburg M (2008), Innate production of tumour necrosis factor alpha and interleukin 10 is associated with radiological progression of knee osteoarthritis, Annals of the Rheumatic Diseases 67(8).
- Emery P, Breedveld FC, Hall S, Durez P, Chang DJ, Robertson D, Singh A, Pedersen RD, Koenig AS & Freundlich B (2008), Comparison of methotrexate monotherapy with a combination of methotrexate and etanercept in active, early, moderate to severe rheumatoid arthritis (COMET): a randomised, double-blind, parallel treatment trial, Lancet 372(9636).
- Emery P, Breedveld FC, Hall S, Durez P, Chang DJ, Pedersen R, Koenig AS, Robertson D & Freundlich B (2008), Clinical remission, radiographic non-progression, and normalized function with the combination of etanercept and methotrexate in the treatment of early active rheumatoid arthritis: 1-year results of the COMET trial, Arthritis and Rheumatism 58(9).
- Botha-Scheepers S, Watt I, Rosendaal FR, Breedveld FC, le Graverand MPH & Kloppenburg M (2008), Changes in Outcome Measures for Impairment, Activity Limitation, and Participation Restriction Over Two Years in Osteoarthritis of the Lower Extremities, Arthritis and Rheumatism 59(12).
- Emery P, Breedveld F, Koenig AS & Robertson D (2008), COMET results are not stellar Reply, Lancet 372(9652).
- Teng, Y.K.O.; Tekstra, J.; Breedveld, F.C.; Lafeber, F.P.; Bijlsma, J.W.J. & Laar, J.M. van (2008), Rituximab fixed retreatment versus on-demand retreatment in refractory rheumatoid arthritis: Comparison of two B-cell depleting treatment strategies, Arthritis and Rheumatism 58(9).
- Aletaha D, Furovits J, Segurado O, Breedveld F & Smolen J (2008), Scores of rheumatoid arthritis (RA) disease activity indices can be mapped to ACR responses, and vice versa, Arthritis and Rheumatism 58(9).
- Breedveld FC, Kavanaugh A, van Riel P, Patra K, Pangan A & Perez JL (2008), Initial combination therapy with adalimumab and methotrexate sustains clinical remission and response for early RA patients treated through year 5, Arthritis and Rheumatism 58(9).
- van der Kooij SM, Goekoop-Ruiterman YPM, de Vries-Bouwstra JK, Peeters AJ, van Krugten MV, Breedveld FC, Dijkmans BAC & Allaart CF (2008), Probability of continued low disease activity in patients with recent onset rheumatoid arthritis treated according to the disease activity score, Annals of the Rheumatic Diseases 67(2).
- van der Kooij SM, de Vries-Bouwstra JK, Goekoop-Ruiterman YPM, van Zeben D, Kerstens PJSM, Gerards AH, van Groenendael JHLM, Hazes JMW, Breedveld FC, Allaart CF & Dijkmans BAC (2007), Limited efficacy of conventional DMARDs after initial methotrexate failure in patients with recent onset rheumatoid arthritis treated according to the disease activity score, Annals of the Rheumatic Diseases 66(10).
- van der Kooij SM, Goekoop-Ruiterman YPM, de Vries-Bouwstra JK, van der Lubbe PAH, van Krugten MV, Breedveld FC, Dijkmans BAC & Allaart CF (2007), Initial versus delayed treatment with infliximab plus methotrexate in patients with early rheumatoid arthritis: Results from the best study, Annals of the Rheumatic Diseases 66.
- Botha-Scheepers S, Watt I, Slagboom E, Craen AJM, Meulenbelt I, Rosendaal F, Breedveld FC, Huizinga TWJ & Kloppenburg M (2007), Innate production of tumor necrosis factor-alpha and interleukin-10 is associated with radiological progression of knee osteoarthritis, Annals of the Rheumatic Diseases 66.
- van der Bijl AE, Allaart CF, Breedveld FC, Kerstens PJSM & Dijkmans BAC (2007), Why publish a secondary analysis of only one treatment group in the Behandelstrategieen voor Reumatoide Artritis trial? Comment on the article by van der Bijl et al - Reply, Arthritis and Rheumatism 56(11).
- Kloppenburg M, Stamm T, Watt I, Kainberger F, Cawston TE, Birrell FN, Petersson IF, Saxne T, Kvien TK, Slatkowsky-Christensen B, Dougados M, Gossec L, Breedveld FC & Smolen JS (2007), Research in hand osteoarthritis: Time for reappraisal and demand for new strategies. An opinion paper, Annals of the Rheumatic Diseases 66(9).
- Verpoort KN, Cheung K, Ioan-Facsinay A, Mil AVHV, de Vries R, Breedveld FC, Huizinga TWJ, Pruijn GJM & Toes REM (2007), Fine-specificity of the antibodies against citrullinated protein response is influenced by shared epitope alleles, Arthritis Research and Therapy 9.
- Verpoort KN, Cheung K, Ioan-Facsinay A, van der Helm-van Mil AHM, de Vries-Bouwstra JK, Allaart CF, Drijfhout JW, de Vries RRP, Breedveld FC, Huizinga TWJ, Pruijn GJM & Toes REM (2007), Fine specificity of the anti-citrullinated protein antibody response is influenced by the shared epitope alleles, Arthritis and Rheumatism 56(12).
- Guler-Yuksel M, Bijsterbosch J, Goekoop-Ruiterman YPM, de Vries-Bouwstra JK, Ronday HK, Peeters AJ, de Jonge-Bok JM, Breedveld FC, Dijkmans BAC, Allaart CF & Lems WF (2007), Bone mineral density in patients with recently diagnosed, active rheumatoid arthritis, Annals of the Rheumatic Diseases 66(11).
- Verpoort KN, Voort EAMP, Mil AHMV, Zijde CMJ, van Tol MJD, Drijfhout JW, Breedveld FC, de Vries RRP, Huizinga TWJ & Toes REM (2007), Association of smoking with the constitution of the anti-cyclic citrullinated peptide response in the absence of HLA-DRB1 shared epitope alleles, Arthritis and Rheumatism 56(9).
- Verhoef J, Toussaint PJ, Zwetsloot-Schonk JHM, Breedveld FC, Putter H & Vlieland TPMV (2007), Effectiveness of the introduction of an international classification of functioning, disability and health-based rehabilitation tool in multidisciplinary team care in patients with rheumatoid arthritis, Arthritis and Rheumatism 57(2).
- Linn-Rasker SP, van der Helm-van Mil AHM, Breedveld FC & Huizinga TWJ (2007), Arthritis of the large joints - in particular, the knee - at first presentation is predictive for a high level of radiological destruction of the small joints in rheumatoid arthritis, Annals of the Rheumatic Diseases 66(5).
- van Dongen H, van Aken J, Lard LR, Visser K, Ronday HK, Hulsmans HMJ, Speyer I, Westedt ML, Peeters AJ, Allaart CF, Toes REM, Breedveld FC & Huizinga TWJ (2007), Efficacy of methotrexate treatment in patients with probable rheumatoid arthritis - A double-blind, randomized, placebo-controlled trial, Arthritis and Rheumatism 56(5).
- de Vries-Bouwstra JK, Goekoop-Ruiterman YPM, Wesoly J, Hulsmans HJ, de Craen AJM, Breedveld FC, Dijkmans BAC, Allaart CF & Huizinga TWJ (2007), Ex vivo interleukin 1 receptor antagonist production on lipopolysaccharide stimulation is associated with rheumatoid arthritis and with joint damage, Annals of the Rheumatic Diseases 66(8).
- Goekoop-Ruiterman YPM, de Vries-Bouwstra JK, Allaart CF, Kerstens PJSM, Grillet BAM, de Jager MH, Han KH, Speyer I, van der Lubbe PAHM, Seys PEH, Breedveld FC & Dijkmans BAC (2007), Patient preferences for treatment: report from a randomised comparison of treatment strategies in early rheumatoid arthritis (BeSt trial), Annals of the Rheumatic Diseases 66(9).
- Botha-Scheepers SA, Watt I, Slagboom E, Meulenbelt I, Rosendaal FR, Breedveld FC & Kloppenburg M (2007), Influence of familial factors on radiologic disease progression over two years in siblings with osteoarthritis at multiple sites: A prospective longitudinal cohort study, Arthritis and Rheumatism 57(4).
- Guller-Yuksel M, Breedveld FC, Allaart CF, Dijkmans BAC & Lems WF (2007), Bone mineral density (BMD) in patients with rheumatoid arthritis (RA): 1 year follow-up in the best study, Osteoporosis International 18.
- van der Kooij SM, van der Bijl AE, Allaart CF, Goekoop-Ruiterman YPM, de Vries-Bouwstra JK, Guler-Yuksel M, van Schaardenburg D, Grillet BAM, Breedveld FC & Dijkmans BAC (2007), Remission induction in early rheumatoid arthritis with initial infliximab and methotrexate therapy: 4-year follow-up data of the disease course after infliximab discontinuation in the best trial, Annals of the Rheumatic Diseases 66.
- Botha-Scheepers S, Riyazi N, Watt I, Rosendaal FR, Slagboom E, Bellamy N, Breedveld FC & Kloppenburg M (2007), Progression of hand osteoarthritis over two years: A clinical and radiological follow-up study, Annals of the Rheumatic Diseases 66.
- Coombs JH, Bloom BJ, Breedveld FC, Fletcher MP, Gruben D, Kremer JM, Krishnaswami S, Burgos-Vargas R, Wilkinson B, Zerbini CAF & Zwillich SH (2007), Improvements in pain, function, and health status in patients taking CP-690,550, an orally active inhibitor of janus kinase 3 (JAK3I): Results from a randomized, double-blind, placebo-controlled trial in the treatment of active rheumatoid arthritis, Annals of the Rheumatic Diseases 66.
- van Vollenhoven RF, Ferraccioli G, Breedveld F, Ray S & Cifaldi M (2007), Effect of adalimumab combination therapy on work performance: Results from a companion study to premier, Annals of the Rheumatic Diseases 66.
- Emery P, Breedveld F, Martin-Mola E, Pavelka K, Szczepanski L, Hagerty D, Magrini F, Behrendt C & Kelman A (2007), Relationship between peripheral B cell levels and loss of EULAR response in rheumatoid arthritis patients treated with rituximab, Annals of the Rheumatic Diseases 66.
- van der Kooij SM, Goekoop-Ruiterman YPM, de Vries-Bouwstra JK, Hazes JMW, Kerstens PJS, van Zeben D, Han KH, Hulsmans HMJ, Breedveld FC, Dijkmans BAC & Allaart CF (2007), Clinical and radiological efficacy of four different treatment strategies in patients with early rheumatoid arthritis: 3-year follow-up of the best study, Annals of the Rheumatic Diseases 66.
- Gilworth G, Emery P, Gossec L, Vlieland TPMV, Breedveld FC, Heuber A, Schett G & Tennant A (2007), Adaptation and cross-cultural validation of the RA-WIS, Annals of the Rheumatic Diseases 66.
- Breedveld FC, Bloom BJ, Coombs J, Fletcher MP, Gruben D, Kremer JM, Krishnaswami S, Burgos-Vargas R, Zerbini C, Wilkinson B & Zwillich SH (2007), 6 weeks of treatment of active rheumatoid arthritis with an orally active inhibitor of JANUS kinase 3, cp-690,550, is associated with dose-dependent increases in remission rates and improvement in the CDAI and SDAI, Annals of the Rheumatic Diseases 66.
- Emery P, Breedveld F, Hall S, Durez P, Pedersen R, Robertson D, Freundlich B & Chang DJ (2007), Remission rates in subjects with active early rheumatoid arthritis 1 year results of the COMET trial: Combination of methotrexate and etanercept in active early rheumatoid arthritis, Arthritis and Rheumatism 56(12).
- Goekoop-Ruiterman YPM, de Vries-Bouwstra JK, Allaart CF, van Zeben D, Kerstens PJSM, Hazes JMW, Zwinderman AH, Peeters AJ, de Jonge-Bok JM, Mallee C, de Beus WM, de Sonnaville PBJ, Ewals JAPM, Breedveld FC & Dijkmans BAC (2007), Comparison of treatment strategies in early rheumatoid arthritis - A randomized trial, Annals of Internal Medicine 146(6).
- van der Bijl AE, Emmer BJ, Breedveld FC, Middelkoop HAM, Jurgens CK, van Buchem MA, Huizinga TWJ & van der Grond J (2007), Advanced magnetic resonance imaging of the brain in patients treated with TNF-alpha blocking agents, Clinical and Experimental Rheumatology 25(2).
- Botha-Scheepers S, Kloppenburg M, Kroon HM, Le Graverand MPH, Breedveld FC, Ravaud P & Dougados M (2007), Fixed-flexion knee radiography: the sensitivity to detect knee joint space narrowing in osteoarthritis, Osteoarthritis and Cartilage 15(3).
- van den Berg MH, Ronday HK, Peeters AJ, Voogt-Van Der Harst EM, Munneke M, Breedveld FC & Vlieland TPMV (2007), Engagement and satisfaction with an Internet-based physical activity intervention in patients with rheumatoid arthritis, Rheumatology 46(3).
- van den Berg MH, de Boer IG, le Cessie S, Breedveld FC & Vlieland TPMV (2007), Most people with rheumatoid arthritis undertake leisure-time physical activity and exercise in the Netherlands: an observational study, Australian Journal of Physiotherapy 53(2).
- Breedveld FC (2007), The future of EULAR in Europe, Annals of the Rheumatic Diseases 66.
- van Dongen H, van Aken J, Lard LR, Visser K, Ronday HK, Hulsmans HMJ, Speyer I, Westedt ML, Peeters AJ, Allaart CF, Toes REM, Breedveld FC & Huizinga TWJ (2007), The probable rheumatoid arthritis: Methotrexate versus placebo treatment (the prompt) study: A double-blind randomized controlled trial, Annals of the Rheumatic Diseases 66.
- van der Helm-van Mil AHM, le Cessie S, van Dongen H, Breedveld FC, Toes REM & Huizinga TWJ (2007), A prediction rule for disease outcome in patients with recent-onset undifferentiated arthritis - How to guide individual treatment decisions, Arthritis and Rheumatism 56(2).
- van der Bijl AE, Goekoop-Ruiterman YPM, de Vries-Bouwstra JK, ten Wolde S, Han KH, van Krugten MV, Allaart CF, Breedveld FC & Dijkmans BAC (2007), Infliximab and methotrexate as induction therapy in patients with early rheumatoid arthritis, Arthritis and Rheumatism 56(7).
- Breedveld FC, Khraishi MM, Genovese M, Emery P, Moreland LW, Keystone E, Matteson EL, Burke L, Agarwal S, Kim D & Cooper S (2007), Safety of TNF inhibitors in rheumatoid arthritis patients previously treated with rituximab, Journal of Rheumatology 34(7).
- Smolen JS, Keystone EC, Emery P, Breedveld FC, Betteridge N, Burmester GR, Dougados M, Ferraccioli G, Jaeger U, Klareskog L, Kvien TK, Martin-Mola E & Pavelka K (2007), Consensus statement on the use of rituximab in patients with rheumatoid arthritis, Annals of the Rheumatic Diseases 66(2).
- Combe B, Landewe R, Lukas C, Bolosiu HD, Breedveld F, Dougados M, Emery P, Ferraccioli G, Hazes JMW, Klareskog L, Machold K, Martin-Mola E, Nielsen H, Silman A, Smolen J & Yazici H (2007), EULAR recommendations for the management of early arthritis: report of a task force of the European Standing Committee for International Clinical Studies Including Therapeutics (ESCISIT), Annals of the Rheumatic Diseases 66(1).
- Allaart CF, Breedveld FC & Dijkmans BAC (2007), Treatment of recent-onset rheumatoid arthritis: Lessons from the BeSt study, Journal of Rheumatology 34.
- van den Berg MH, de Boer IG, le Cessie S, Breedveld FC & Vlieland TPMV (2007), Are patients with rheumatoid arthritis less physically active than the general population?, JCR: Journal of Clinical Rheumatology 13(4).
- Breedveld F, Agarwal S, Yin M, Ren S, Li NF, Shaw TM & Davies BE (2007), Rituximab pharmacokinetics in patients with rheumatoid arthritis: B-cell levels do not correlate with clinical response, Journal of Clinical Pharmacology 47(9).
- Laar, J.M. van; Melchers, M.; Teng, Y.K.O.; Zouwen, B. van der; Mohammadi, R.; Fischer, R.; Margolis, L.; Fitzgerald, W.; Grivel, J.C.; Breedveld, F.C.; Lipsky, P.E. & Grammer, A.C. (2007), Sustained secretion of immunoglobulin by long-lived human tonsil plasma cells, American Journal of Pathology 171(3).
- Furst DE, Breedveld FC, Kalden JR, Smolen JS, Burmester GR, Sieper J, Emery P, Keystone EC, Schiff MH, Mease P, van Riel PLCM, Fleischmann R, Weisman MH & Weinblatt ME (2007), Updated consensus statement on biological agents for the treatment of rheumatic diseases, 2007, Annals of the Rheumatic Diseases 66.
- van Oosterhous M, Sont JK, Bajema IM, Breedveld FC, van Laar JM & Moseley B (2007), Arthroscopic lavage plus corticosteroids was more effective than arthroscopic lavage plus placebo or joint aspiration plus corticosteroids for arthritis of the knee, Journal of Bone and Joint Surgery, American Volume 89A(5).
- Van der Helm-van Mil AHM, Verpoort KN, Breedveld FC, Huizinga TWJ, Toes REM & De Vries RRP (2006), The HLA-DRB1 shared epitope alleles are primarily a risk factor for anti-CCP antibodies and are not an independent risk factor to develop rheumatoid arthritis, Annals of the Rheumatic Diseases 65: 74-74.
- De Vries-Bouwstra JK, Goekoop-Ruiterman YPM, Verpoort KN, Schreuder GMT, De Bois MHW, Mallee C, Toes REM, De Vries RRP, Breedveld FC, Dijkmans BAC, Huizinga TWJ & Allaart CF (2006), The association of HLA class II antigens and anti-CCP antibodies with progression of joint damage is affected by early and targeted treatment of rheumatoid arthritis, Annals of the Rheumatic Diseases 65: 88-89.
- Verpoort, K.N.; Jol-van Der Zijde, C.M.; Papendrecht-van der Voort, E.A.M.; Ioan-Facsinay, A.; Drijfhout, J.W.; Tol, M.J.D. van; Breedveld, F.C.; Huizinga, T.W.J. & Toes, R.E.M. (2006), Isotypes of anti-citrullinated peptide antibodies (ACPA) in undifferentiated arthritis and rheumatoid arthritis suggest an ongoing immune response, Annals of the Rheumatic Diseases 65: 102-102.
- Van der Bijl AE, Van der Kooij SM, Goekoop-Ruiterman YP, de Vries-Bouwstra JK, Breedveld FC, Allaart CF & Dijkmans BA (2006), Persistent good clinical response after tapering and discontinuation of initial infliximab therapy in patients with early rheumatoid arthritis: 3-year results from the best trial, Annals of the Rheumatic Diseases 65: 109-109.
- Van der Kooij SM, De Vries-Bouwstra JK, Goekoop-Ruiterman YPM, Van Zeben D, Kerstens PJSM, Peeters AJ, De Jonge-Bok JM, Hazes JMW, Breedveld FC, Allaart CF & Dijkmans BAC (2006), Joint damage progression in early rheumatoid arthritis patients despite continued conventional treatment after failure on initial methotrexate, Annals of the Rheumatic Diseases 65: 347-348.
- van Oosterhout M, Sont JK, Bajema IM, Breedveld FC & van Laar JM (2006), Comparison of efficacy of arthroscopic lavage plus administration of corticosteroids, arthroscopic lavage plus administration of placebo, and joint aspiration plus administration of corticosteroids in arthritis of the knee: A randomized controlled trial, Arthritis and Rheumatism 55(6).
- van den Berg MH, Ronday HK, Peeters AJ, le Cessie S, van der Giesen FJ, Breedveld FC & Vlieland TPMV (2006), Using Internet technology to deliver a home-based physical activity intervention for patients with rheumatoid arthritis: A randomized controlled trial, Arthritis and Rheumatism 55(6).
- Verpoort KN, Jol-van der Zijde CM, Papendrecht-van der Voort EAM, Ioan-Facsinay A, Drijfhout JW, van Tol MJD, Breedveld FC, Huizinga TWJ & Toes REM (2006), Isotype distribution of anti-cyclic citrullinated peptide antibodies in undifferentiated arthritis and rheumatoid arthritis reflects an ongoing immune response, Arthritis and Rheumatism 54(12).
- Meulenbelt I, Min JL, van Duijn CM, Kloppenburg M, Breedveld FC & Slagboom PE (2006), Strong linkage on 2q33.3 to familial early-onset generalized osteoarthritis and a consideration of two positional candidate genes, European Journal of Human Genetics 14(12).
- Allaart CF, Goekoop-Ruiterman YPM, de Vries-Bouwstra JK, Breedveld FC & Dijkmans BAC (2006), Aiming at low disease activity in rheumatoid arthritis with initial combination therapy or initial monotherapy strategies: the BeSt study, Clinical and Experimental Rheumatology 24(6).
- Botha-Scheepers S, Riyazi N, Kroon HM, Scharloo M, Houwing-Duistermaat JJ, Slagboom E, Rosendaal FR, Breedveld FC & Kloppenburg M (2006), Activity limitations in the lower extremities in patients with osteoarthritis: the modifying effects of illness perceptions and mental health, Osteoarthritis and Cartilage 14(11).
- Remans PHJ, Wijbrandts CA, Sanders ME, Toes RE, Breedveld FC, Tak PP, van Laar JM & Reedquist KA (2006), CTLA-4Ig suppresses reactive oxygen species by preventing synovial adherent cell-induced inactivation of Rap1, a Ras family GTPase mediator of oxidative stress in rheumatoid arthritis T cells, Arthritis and Rheumatism 54(10).
- Furst DE, Breedveld FC, Kalden JR, Smolen JS, Burmester GR, Emery P, Keystone EC, Schiff MH, van Riel PLCM, Weinblatt ME & Weisman MH (2006), Updated consensus statement on biological agents for the treatment of rheumatic diseases, 2006, Annals of the Rheumatic Diseases 65.
- Botha-Scheepers S, Watt I, Slagboom E, de Craen T, Meulenbelt I, Rosendaal FR, Breedveld FC, Huizinga TWJ & Kloppenburg M (2006), Innate production of tumor necrosis factor-alpha and interleukin-10 upon lipopolysaccharide stimulation are associated with radiological progression of knee osteoarthritis., Arthritis and Rheumatism 54(9).
- van der Helm-van Mil AHM, Breedveld FC & Huizinga TWJ (2006), Aspects of early arthritis - Definition of disease states in early arthritis: Remission versus minimal disease activity, Arthritis Research and Therapy 8(4).
- de Vries-Bouwstra J, Le Cessie S, Allaart C, Breedveld F & Huizinga T (2006), Using predicted disease outcome to provide differentiated treatment of early rheumatoid arthritis, Journal of Rheumatology 33(9).
- van den Bemt BJ, van den Hoogen FH, Breedveld FC, van der Tempel H & Janknegt R (2006), InforMatrix((R)): treatment of rheumatoid arthritis using biologicals, Expert Opinion on Pharmacotherapy 7(13).
- Haringman JJ, Gerlag DM, Smeets TJM, Baeten D, Van den Bosch F, Bresnihan B, Breedveld FC, Dinant HJ, Legay F, Gram H, Loetscher P, Schmouder R, Woodworth T & Tak PP (2006), A randomized controlled trial with an anti-CCL2 (anti-monocyte chemotactic protein 1) monoclonal antibody in patients with rheumatoid arthritis, Arthritis and Rheumatism 54(8).
- Botha-Scheepers S, Dougados M, Ravaud P, Le Graverand MH, Watt I, Breedveld FC & Kloppenburg M (2006), Effect of medial tibial plateau alignment on serial radiographs on the capacity to detect predisposing factors of progression of knee osteoarthritis, Annals of the Rheumatic Diseases 65.
- Goekoop-Ruiterman YPM, Allaart CF, Breedveld FC, de Vries-Bowstra JK & Dijkmans BAC (2006), How should best strategy and tight control be translated into clinical practice? Comment on the article by Goekoop-Ruiterman et al - Reply, Arthritis and Rheumatism 54(7).
- Botha-Scheepers S, Kloppenburg M, Kroon HM, Le Graverand MH, Breedveld FC, Ravaud P & Dougados M (2006), Fixed-flexion knee radiography: The long-term reproducibility and sensitivity to detect knee joint space narrowing in osteoarthritis, Annals of the Rheumatic Diseases 65.
- De Boer IG, Peeters AJ, Ronday HK, Mertens BJA, Breedveld FC & Vlieland TPMV (2006), Possession of assistive devices in patients with rheumatoid arthritis, Annals of the Rheumatic Diseases 65.
- van Aken J, van Dongen H, le Cessie S, Allaart CF, Breedveld FC & Huizinga TWJ (2006), Comparison of long term outcome of patients with rheumatoid arthritis presenting with undifferentiated arthritis or with rheumatoid arthritis: an observational cohort study, Annals of the Rheumatic Diseases 65(1).
- Vermeulen HM, Breedveld FC, Le Cessie S, Rozing PM, van den Ende CHM & Vlieland TPMV (2006), Responsiveness of the shoulder function assessment scale in patients with rheumatoid arthritis, Annals of the Rheumatic Diseases 65(2).
- Breedveld FC, Weisman MH, Kavanaugh AF, Cohen SB, Pavelka K, van Vollenhoven R, Sharp J, Perez JL & Spencer-Green GT (2006), The PREMIER study - A multicenter, randomized, double-blind clinical trial of combination therapy with adalimumab plus methotrexate versus methotrexate alone or adalimumab alone in patients with early, aggressive rheumatoid arthritis who had not had previous methotrexate treatment, Arthritis and Rheumatism 54(1).
- Hoeksma HL, van den Ende CHM, Breedveld FC, Ronday HK & Dekker J (2006), A comparison of the OARSI response criteria with patient's global assessment in patients with osteoarthritis of the hip treated with a non-pharmacological intervention, Osteoarthritis and Cartilage 14(1).
- Linn-Rasker SP, van der Helm-van Mil AHM, van Gaalen FA, Kloppenburg M, de Vries RRP, le Cessie S, Breedveld FC, Toes REM & Huizinga TWJ (2006), Smoking is a risk factor for anti-CCP antibodies only in rheumatoid arthritis patients who carry HLA-DRB1 shared epitope alleles, Annals of the Rheumatic Diseases 65(3).
- Schoe A, van der Laan-Baalbergen NE, Huizinga TWJ, Breedveld FC & van Laar JM (2006), Pulmonary fibrosis in a patient with rheumatoid arthritis treated with adalimumab, Arthritis and Rheumatism 55(1).
- Wessels JAM, de Vries-Bouwstra JK, Heijmans BT, Slagboom PE, Goekoop-Ruiterman YPM, Allaart CF, Kerstens PJSM, van Zeben D, Breedveld FC, Dijkmans BAC, Huizinga TWJ & Guchelaar HJ (2006), Efficacy and toxicity of methotrexate in early rheumatoid arthritis are associated with single-nucleotide polymorphisms in genes coding for folate pathway enzymes, Arthritis and Rheumatism 54(4).
- van der Helm-van Mil AHM, Verpoort KN, Breedveld FC, Huizinga TWJ, Toes REM & de Vries RRP (2006), The HLA-DRB1 shared epitope alleles are primarily a risk factor for anti-cyclic citrullinated peptide antibodies and are not an independent risk factor for development of rheumatoid arthritis, Arthritis and Rheumatism 54(4).
- Verpoort KN, van Gaalen FA, van der Helm-van Mil A, Schreuder GMT, Breedveld FC, Huizinga TWJ, de Vries RRP & Toes REM (2005), Hla-dr3 is associated with anti-ccp antibody negative rheumatoid arthritis., Arthritis and Rheumatism 52(9): S150-S150.
- Verpoort KN, van Gaalen FA, Helm-Van Mil AHMVD, Schreuder GMT, de Vries RRP, Breedveld FC, Huizinga TWJ & Toes REM (2005), HLA DR3 is associated with anti-CCP negative rheumatoid arthritis, Annals of the Rheumatic Diseases 64: 120-120.
- Breedveld FC, Han C, Bala M, van der Heijde D, Baker D, Kavanaugh AF, Maini RN & Lipsky PE (2005), Association between baseline radiographic damage and improvement in physical function after treatment of patients with rheumatoid arthritis, Annals of the Rheumatic Diseases 64(1).
- van den Hout WB, de Jong Z, Munneke M, Hazes JMW, Breedveld FC & Vlieland TPMV (2005), Cost-utility and cost-effectiveness analyses of a long-term, high-intensity exercise program compared with conventional physical therapy in patients with rheumatoid arthritis, Arthritis and Rheumatism 53(1).
- Riyazi N, Meulenbelt I, Kroon HM, Ronday KH, le Graverand MPH, Rosendaal FR, Breedveld FC, Slagboom PE & Kloppenburg M (2005), Evidence for familial aggregation of hand, hip, and spine but not knee osteoarthritis in siblings with multiple joint involvement: the GARP study, Annals of the Rheumatic Diseases 64(3).
- Hoeksma HL, Dekker J, Ronday HK, Breedveld FC & Van den Ende CHM (2005), Manual therapy in osteoarthritis of the hip: outcome in subgroups of patients, Rheumatology 44(4).
- Smolen JS, Han C, Bala M, Maini RN, Kalden JR, van der Heijde D, Breedveld FC, Furst DE & Lipsky PE (2005), Evidence of radiographic benefit of treatment with infliximab plus methotrexate in rheumatoid arthritis patients who had no clinical improvement - A detailed subanalysis of data from the anti-tumor necrosis factor trial in rheumatoid arthritis with concomitant therapy study, Arthritis and Rheumatism 52(4).
- Riyazi N, Slagboom E, de Craen AJM, Meulenbelt I, Houwing-Duistermaat JJ, Kroon HM, van Schaardenburg D, Rosendaal FR, Breedveld FC, Huizinga TWJ & Kloppenburg M (2005), Association of the risk of osteoarthritis with high innate production of interleukin-1 beta and low innate production of interleukin-10 ex vivo, upon lipopolysaccharide stimulation, Arthritis and Rheumatism 52(5).
- Wessels JAM, De Vries-Bouwstra JK, Heijmans BT, Goekoop-Ruiterman YPM, Allaart CF, Kerstens PJS, Van Zeben D, Breedveld FC, Dijkmans BAC, Huizinga TWJ & Guchelaar H (2005), Efficacy and toxicity of methotrexate in early rheumatoid arthritis are associated with single nucleotide polymorphisms in genes coding for folate pathway enzymes, Annals of the Rheumatic Diseases 64.
- De Buck PDM, Le Cessie S, Van den Hout WB, Peeters AJ, Ronday HK, Speyer I, Breedveld FC & Vlieland TPMV (2005), A randomised comparison of a multidisciplinary job retention vocational rehabilitation programme with usual outpatient care in patients with chronic arthritis at risk for job loss, Annals of the Rheumatic Diseases 64.
- Van den Berg MH, Ronday HK, Peeters AJ, Le Cessie S, Breedveld FC & Vlieland TPMV (2005), Using internet technology to deliver a home-based physical activity intervention for patients with rheumatoid arthritis: A randomized controlled trial, Annals of the Rheumatic Diseases 64.
- Van Aken J, Van Dongen H, Le Cessie S, Allaart CF, Breedveld FC & Huizinga TJ (2005), Long term outcome of rheumatoid arthritis that presented with undifferentiated arthritis compared to rheumatoid arthritis at presentation - An observational cohort study, Annals of the Rheumatic Diseases 64.
- Botha-Scheepers SA, Kroon HM, Slagboom E, Rosendaal FR, Breedveld FC & Klopppenburg M (2005), The natural history and determinants of lower extremity functioning over two years in osteoarthritis, Annals of the Rheumatic Diseases 64.
- Riyazi N, Botha-Scheepers SA, Houwing-Duistermaat JJ, Kroon HM, Rosendaal FR, Slagboom E, Breedveld FC & Kloppenburg M (2005), Why is there a discrepancy between disease and disability in osteoarthritis in the hands?, Annals of the Rheumatic Diseases 64.
- De Boer IG, Peeters AJ, Ronday HK, Mertens BJA, Breedveld FC & Vlieland TPMV (2005), Functional wrist orthoses in patients with rheumatoid arthritis: Factors contributing to possession and use, Annals of the Rheumatic Diseases 64.
- Tolboom TCA, Mil AHMVDV, Nelissen RGHH, Breedveld FC, Toes REM & Huizinga TWJ (2005), Invasiveness of fibroblast-like synoviocytes is an individual patient characteristic associated with the rate of joint destruction in patients with rheumatoid arthritis, Arthritis and Rheumatism 52(7).
- Remans PHJ, van Oosterhout M, Smeets TJM, Sanders M, Frederiks WM, Reedquist KA, Tak PP, Breedveld FC & van Laar JM (2005), Intracellular free radical production in synovial T lymphocytes from patients with rheumatoid arthritis, Arthritis and Rheumatism 52(7).
- van der Helm-van Mil AHM, Verpoort KN, Breedveld FC, Toes REM & Huizinga TWJ (2005), Antibodies to citrullinated proteins and differences in clinical progression of rheumatoid arthritis, Arthritis Research and Therapy 7(5).
- Teng, Y.K.O.; Verburg, R.J.; Sont, J.K.; Hout, W.B. van den; Breedveld, F.C. & Laar, J.A. van (2005), Long-term followup of health status in patients with severe rheumatoid arthritis after high-dose chemotherapy followed by autologous hematopoietic stem cell transplantation, Arthritis and Rheumatism 52(8).
- van der Bijl AE, Allaart CF, van Vugt JPP, van Duinen SG & Breedveld FC (2005), Rheumatoid vasculitis treated with infliximab, Journal of Rheumatology 32(8).
- van der Helm-van Mil AHM, Huizinga TWJ, Schreuder GMT, Breedveld FC, de Vries RRP & Toes REM (2005), An independent role of protective HLA class II alleles in rheumatoid arthritis severity and susceptibility, Arthritis and Rheumatism 52(9).
- Botha-Scheepers SA, Watt I, Rosendaal FR, Breedveld FC, Slagboom E & Kloppenburg M (2005), Familial aggregation of radiological progression in siblings with symptomatic osteoarthritis at multiple sites: The GARP study, Arthritis and Rheumatism 52(9).
- Wessels JAM, de Vries-Bouwstra JK, Heijmans BT, Goekoop-Ruiterman YPM, Allaart CF, Kerstens PJ, van Zeben D, Breedveld FC, Dijkmans BAC, Huizinga TWJ & Guchelaar HJ (2005), Single nucleotide polymorphisms in genes coding for folate pathway enzymes are determinants for methotrexate efficacy in early rheumatoid arthritis, Arthritis and Rheumatism 52(9).
- van den Berg MH, Ronday HK, Peeters AJ, le Cessie S, Breedveld FC & Vlieland TPV (2005), Using Internet technology to deliver a home-based physical activity intervention for patients with rheumatoid arthritis: A randomized controlled trial., Arthritis and Rheumatism 52(9).
- Verpoort KN, van Gaalen FA, van der Helm-van Mil AHM, Schreuder GMT, Breedveld FC, Huizinga TWJ, de Vries RRP & Toes REM (2005), Association of HLA-DR3 with anti-cyclic citrullinated peptide antibody-negative rheumatoid arthritis, Arthritis and Rheumatism 52(10).
- Botha-Scheepers S, Watt I, Breedveld FC & Kloppenburg M (2005), Reading radiographs in pairs or in chronological order influences radiological progression in osteoarthritis, Rheumatology 44(11).
- Furst DE, Breedveld FC, Kalden JR, Smolen JS, Burmester GR, Bijlsma JWJ, Dougados M, Emery P, Keystone EC, Klareskog L & Mease PJ (2005), Updated consensus statement on biological agents, specifically tumour necrosis factor alpha (TNF alpha) blocking agents and interleukin-1 receptor antagonist (IL-1ra), for the treatment of rheumatic diseases, 2005, Annals of the Rheumatic Diseases 64.
- de Buck PDM, le Cessie S, van den Hout WB, Peeters AJ, Ronday HK, Westedt ML, Breedveld FC & Vlieland TPM (2005), Randomized comparison of a multidisciplinary job-retention vocational rehabilitation program with usual outpatient care in patients with chronic arthritis at risk for job loss, Arthritis and Rheumatism 53(5).
- Aletaha D, Breedveld FC & Smolen JS (2005), The need for new classification criteria for rheumatoid arthritis, Arthritis and Rheumatism 52(11).
- Goekoop-Ruiterman YPM, de Vries-Bouwstra JK, Allaart CF, van Zeben D, Kerstens PJSM, Hazes JMW, Zwinderman AH, Ronday HK, Han KH, Westedt ML, Gerards AH, van Groenendael JHLM, Lems WF, van Krugten MV, Breedveld FC & Dijkmans C (2005), Clinical and radiographic outcomes of four different treatment strategies in patients with early rheumatoid arthritis (the BeSt study) - A randomized, controlled trial, Arthritis and Rheumatism 52(11).
- Huizinga TWJ, Amos CI, van der Helm-van Mil AHM, Chen W, van Gaalen FA, Jawaheer D, Schreuder GMT, Wener M, Breedveld FC, Ahmad N, Lum RF, de Vries RRP, Gregersen PK, Toes REM & Criswell LA (2005), Refining the complex rheumatoid arthritis phenotype based on specificity of the HLA-DRB1 shared epitope for antibodies to citrullinated proteins, Arthritis and Rheumatism 52(11).
- de Vries-Bouwstra JK, Dijkmans BAC & Breedveld FC (2005), Biologics in early rheumatoid arthritis, Rheumatic Disease Clinics of North America 31(4).
- Farge D, Passweg J, van Laar JM, Marjanovic Z, Besenthal C, Finke J, Peter HH, Breedveld FC, Fibbe WE, Black C, Denton C, Koetter I, Locatelli F, Martini A, Schattenberg AVN, van den Hoogen F, van de Putte L, Lanza F, Arnold R, Bacon PA, Bingham S, Ciceri F, Didier B, Diez-Martin JL, Emery P, Feremans W, Hertenstein B, Hiepe F, Luosujarvi R, Lara AL, Marmont A, Martinez AM, Cascon HP, Bocelli-Tyndall C, Gluckman E, Gratwohl A & Tyndall A (2004), Autologous stem cell transplantation in the treatment of systemic sclerosis: report from the EBMT/EULAR Registry, Annals of the Rheumatic Diseases 63(8).
- van Gaalen FA, van Aken J, Huizinga TWJ, Schreuder GMT, Breedveld FC, Zanelli E, van Venrooij WJ, Verweij CL, Toes REM & de Vries RRP (2004), Association between HLA class II genes and autoantibodies to cyclic citrullinated peptides (CCPs) influences the severity of rheumatoid arthritis, Arthritis and Rheumatism 50(7).
- Kalden JR, Smolen JS, Emery P, van Riel PLCM, Dougados M, Strand CV & Breedveld FC (2004), Leflunomide in combination therapy, Journal of Rheumatology 31.
- Smolen JS, Emery P, Kalden JR, Van Riel PLCM, Dougados M, Strand CV & Breedveld FC (2004), The efficacy of leflunomide monotherapy in rheumatoid arthritis: Towards the goals of disease modifying antirheumatic drug therapy, Journal of Rheumatology 31.
- van Gaalen FA, van Aken J, Huizinga TW, Schreuder GM, Breedveld FC, Zanelli E, van Venrooij WJ, Verweij C, Toes RE & de Vries R (2004), Association between Hla class Ii genes and autoantibodies to cyclic citrullinated peptides (Ccp) affects severity of rheumatoid arthritis., Arthritis and Rheumatism 50(9): S359-S359.
- van Gaalen FA, Toes REM, Ditzel HJ, Schaller M, Breedveld FC, Verweij CL & Huizinga TWJ (2004), Association of autoantibodies to glucose-6-phosphate isomerase with extraarticular complications in rheumatoid arthritis, Arthritis and Rheumatism 50(2): 395-399.
- Remans PHJ, Sont JK, Wagenaar LW, Wouters-Wesseling W, Zuijderduin WM, Jongma A, Breedveld FC & van Laar JM (2004), Nutrient supplementation with polyunsaturated fatty acids and micronutrients in rheumatoid arthritis: clinical and biochemical effects, European Journal of Clinical Nutrition 58(6).
- van Gaalen FA, Linn-Rasker SP, van Venrooij WJ, de Jong BA, Breedveld FC, Verweij CL, Toes REM & Huizinga TWJ (2004), Autoantibodies to cyclic citrullinated peptides predict progression to rheumatoid arthritis in patients with undifferentiated arthritis - A prospective cohort study, Arthritis and Rheumatism 50(3): 709-715.
- Kraan MC, Smeets TJM, van Loon MJ, Breedveld FC, Dijkmans BAC & Tak PP (2004), Differential effects of leflunomide and methotrexate on cytokine production in rheumatoid arthritis, Annals of the Rheumatic Diseases 63(9).
- Riyazi N, Rosendaal FR, Kroon HM, Slagboon E, Breedveld FC & Kloppenburg M (2004), Environmental risk factors contribute to familial osteoarthritis (OA): A sibling study, Arthritis and Rheumatism 50(9).
- de Jong Z, Munneke M, Zwinderman AH, Kroon HM, Ronday KH, Lems WF, Dijkmans BAC, Breedveld FC, Vlieland TPMV, Hazes JMW & Huizinga TWJ (2004), Long term high intensity exercise and damage of small joints in rheumatoid arthritis, Annals of the Rheumatic Diseases 63(11).
- Breedveld FC & Kalden JR (2004), Appropriate and effective management of rheumatoid arthritis, Annals of the Rheumatic Diseases 63(6).
- Hoeksma HL, Dekker J, Ronday HK, Heering A, van der Lubbe N, Vel C, Breedveld FC & van den Ende CHM (2004), Comparison of manual therapy and exercise therapy in osteoarthritis of the hip: A randomized clinical trial, Arthritis and Rheumatism 51(5).
- Botha-Scheepers SA, Riyazi N, Kroon HM, Slagboom E, Meulebelt I, Rosendaal FR, Breedveld FC & Kloppenburg M (2004), Pain and disability in the lower extremities in patients with osteoarthritis (OA) at multiple sites are associated with lumbar spine OA, the number of oa joints, range of motion and psychological factors, Annals of the Rheumatic Diseases 63.
- Riyazi N, Huizinga TJ, de Craen AR, Meulenbelt I, Kroon HM, Rosendaal R, Breedveld FC, Slagboom E & Kloppenburg M (2004), Identification of three new genetically determined risk factors for osteoarthritis (OA): High levels of interleukin (IL)-1 beta and IL-receptor antagonist (IL-1Ra) and low IL-10 production, Annals of the Rheumatic Diseases 63.
- Riyazi N, Hulzinga TWJ, De Craen AJM, Meulenbelt I, Kroon HM, Rosendaal FR, Breedveld FC, Slagboom E & Kloppenburg M (2004), Identification of three new genetically determined risk factors for osteoarthritis (OA): High levels of interleukin (IL)-1beta and IL-receptor antagonist (IL-1Ra) and low IL-10 production, Annals of the Rheumatic Diseases 63.
- Furst DE, Breedveld FC, Kalden JR, Smolen JS, Burmester GR, Bijlsma JWJ, Dougados M, Emery P, Keystone EC, Klareskog L & Mease PJ (2004), Updated consensus statement on biological agents, specifically tumour necrosis factor alpha (TNF alpha) blocking agents and interleukin-1 receptor antagonist (IL-1ra), for the treatment of rheumatic diseases, 2004, Annals of the Rheumatic Diseases 63.
- Kraan MC, Haringman JJ, Weedon H, Barg EC, Smith MD, Ahern MJ, Smeets TJM, Breedveld FC & Tak PP (2004), T cells, fibroblast-like synoviocytes, and granzyme B plus cytotoxic cells are associated with joint damage in patients with recent onset rheumatoid arthritis, Annals of the Rheumatic Diseases 63(5).
- de Jong Z, Munneke M, Lems WF, Zwinderman AH, Kroon HM, Pauwels EKJ, Jansen A, Ronday KH, Dijkmans BAC, Breedveld FC, Vlieland TPMV & Hazes JMW (2004), Slowing of bone loss in patients with rheumatoid arthritis by long-term high-intensity exercise - Results of a randomized, controlled trial, Arthritis and Rheumatism 50(4).
- Maini RN, Breedveld FC, Kalden JR, Smolen JS, Furst D, Weisman MH, St Clair EW, Keenan GF, van der Heijde D, Marsters PA & Lipsky PE (2004), Sustained improvement over two years in physical function, structural damage, and signs and symptoms among patients with rheumatoid arthritis treated with infliximab and methotrexate, Arthritis and Rheumatism 50(4).
- van Aken J, Lard LR, le Cessie S, Hazes JMW, Breedveld FC & Huizinga TWJ (2004), Radiological outcome after four years of early versus delayed treatment strategy in patients with recent onset rheumatoid arthritis, Annals of the Rheumatic Diseases 63(3).
- Breedveld FC, Emery P, Keystone E, Patel K, Furst DE, Kalden JR, St Clair EW, Weisman M, Smolen J, Lipsky PE & Maini RN (2004), Infliximab in active early rheumatoid arthritis, Annals of the Rheumatic Diseases 63(2).
- Huizinga T, Schonkeren J, Kurreeman F, van Gaalen F, Westendorp R, Breedveld FC & Toes R (2003), Analysis of IL-10 gene variants in rheumatoid arthritis, Arthritis Research and Therapy 5: S25-S25.
- van Gaalen FA, Lard L, Schonkeren J, Pieterman E, Stoeken G, Vos K, Nelissen R, Westendorp R, Hoeben R, Breedveld FC, Toes R & Huizinga TWJ (2003), A polymorphism in the IL-10 promoter affects autoantibody production and subsequent joint destruction in rheumatoid arthritis, Arthritis Research and Therapy 5: S18-S19.
- van Gaalen FA, Linn-Rasker SP, van Venrooij WJ, de Jong BA, Breedveld FC, Verweij CL, Toes REM & Huizinga TWJ (2003), Autoantibodies predict progression to rheumatoid arthritis in undifferentiated arthritis: a prospective cohort study, Arthritis Research and Therapy 5: S9-S9.
- van der Pouw Kraan TCTM, van Gaalen F, Huizinga TWJ, Pieterman E, Breedveld FC & Verweij CL (2003), Discovery of distinctive gene expression profiles in rheumatoid synovium using cDNA microarray technology: evidence for the existence of multiple pathways of tissue destruction and repair, Genes and Immunity 4(3): 187-196.
- Kraan TCTMV, van Gaalen FA, Kasperkovitz PV, Verbeet NL, Smeets TJM, Kraan MC, Fero M, Tak PP, Huizinga TWJ, Pieterman E, Breedveld FC, Alizadeh AA & Verweij CL (2003), Rheumatoid arthritis is a heterogeneous disease - Evidence for differences in the activation of the STAT-1 pathway between rheumatoid tissues, Arthritis and Rheumatism 48(8): 2132-2145.
- Breedveld FC (2003), Should rheumatoid arthritis be treated conservatively or aggressively?, Rheumatology 42.
- van de Putte LBA, Rau R, Breedveld FC, Kalden JR, Malaise MG, van Riel PLCM, Schattenkirchner M, Emery P, Burmester GR, Zeidler H, Moutsopoulos HM, Beck K & Kupper H (2003), Efficacy and safety of the fully human anti-tumour necrosis factor alpha monoclonal antibody adalimumab (D2E7) in DMARD refractory patients with rheumatoid arthritis: a 12 week, phase II study, Annals of the Rheumatic Diseases 62(12).
- Smolen JS, Sokka T, Pincus T & Breedveld FC (2003), A proposed treatment algorithm for rheumatoid arthritis: Aggressive therapy, methotrexate, and quantitative measures, Clinical and Experimental Rheumatology 21(5).
- van Aken J, van Bilsen JHM, Allaart CF, Huizinga TWJ & Breedveld FC (2003), The Leiden Early Arthritis Clinic, Clinical and Experimental Rheumatology 21(5).
- Furst DE, Breedveld FC, Kalden JR, Smolen JS, Burmester GR, Dougados M, Emery P, Gibofsky A, Kavenaugh AF, Keystone EC, Klareskog L, Russell AS, van de Putte LBA & Weisman MH (2003), Updated consensus statement on biological agents for the treatment of rheumatoid arthritis and other immune mediated inflammatory diseases (May 2003), Annals of the Rheumatic Diseases 62.
- Breedveld FC, Kalden JR & Smolen JS (2003), Advances in targeted therapies V, Annals of the Rheumatic Diseases 62.
- De Vries-Bouwstra JK, le Cessie S, Allaart CF, Breedveld FC & Huizinga TWJ (2003), Using predicted disease outcome to provide differentiated treatment of early rheumatoid arthritis., Arthritis and Rheumatism 48(9).
- Tijhuis GJ, Zwinderman AH, Hazes JMW, Breedveld FC & Vlieland PMTV (2003), Two-year follow-up of a randomized controlled trial of a clinical nurse specialist intervention, inpatient, and day patient team care in rheumatoid arthritis, Journal of Advanced Nursing 41(1).
- Riyazi N, Meulenbelt I, Kroon HM, le Graverand MPH, Woodworth T, Rosendaal FR, Breedveld FC, Slagboom PE & Kloppenburg M (2003), Evidence for familial aggregation of hip, hand and spine osteoarthritis (OA) in siblings with clinical and radiological OA. The GARP study., Arthritis and Rheumatism 48(9).
- Emery P, Reece RJ, Kraan MC, O'Connor PJ, Radjenovic A, Veale DJ, Ridgway JP, Gibbon WW, Breedveld FC & Tak PP (2003), Unproven hypothesis that leflunomide is better than methotrexate as measured by magnetic resonance imaging: comment on the article by Reece et al - Reply, Arthritis and Rheumatism 48(1).
- van der Laan WH, Quax PHA, Seemayer CA, Huisman LGM, Pieterman EJ, Grimbergen JM, Verheijen JH, Breedveld FC, Gay RE, Gay S, Huizinga TWJ & Pap T (2003), Cartilage degradation and invasion by rheumatoid synovial fibroblasts is inhibited by gene transfer of TIMP-1 and TIMP-3, Gene Therapy 10(3).
- de Jong Z, Munneke M, Zwinderman AH, Kroon HM, Jansen A, Ronday KH, van Schaardenburg D, Dijkmans BAC, Van den Ende CHM, Breedveld FC, Vlieland TPMV & Hazes JMW (2003), Is a long-term high-intensity safe in patients with exercise program effective and rheumatoid arthritis? Results of a randomized controlled trial, Arthritis and Rheumatism 48(9).
- Hoeksma HL, Van den Ende CHM, Ronday HK, Heering A, Breedveld FC & Dekker J (2003), Comparison of the responsiveness of the Harris Hip Score with generic measures for hip function in osteoarthritis of the hip, Annals of the Rheumatic Diseases 62(10).
- Smolen JS, Breedveld FC, Schiff MH, Kalden JR, Emery P, Eberl G, van Riel PL & Tugwell P (2003), A simplified disease activity index for rheumatoid arthritis for use in clinical practice, Rheumatology 42(2).
- van den Hout WB, Tijhuis GJ, Hazes JMW, Breedveld FC & Vlieland TPMV (2003), Cost effectiveness and cost utility analysis of multidisciplinary care in patients with rheumatoid arthritis: a randomised comparison of clinical nurse specialist care, inpatient team care, and day patient team care, Annals of the Rheumatic Diseases 62(4).
- Tijhuis GJ, Kooiman KG, Zwinderman AH, Hazes JMW, Breedveld FC & Vlieland TPMV (2003), Validation of a novel satisfaction questionnaire for patients with rheumatoid arthritis receiving outpatient clinical nurse specialist care, inpatient care, or day patient team care, Arthritis and Rheumatism 49(2).
- Voskuyl AE, Hazes JMW, Zwinderman AH, Paleolog EM, van der Meer FJM, Daha MR & Breedveld FC (2003), Diagnostic strategy for the assessment of rheumatoid vasculitis, Annals of the Rheumatic Diseases 62(5).
- Arend SM, Breedveld FC & van Dissel JT (2003), TNF-alpha blockade and tuberculosis: better look before you leap, Netherlands Journal of Medicine 61(4).
- Kalden JR, Schattenkirchner M, Sorensen H, Emery P, Deighton C, Rozman B & Breedveld F (2003), The efficacy and safety of leflunomide in patients with active rheumatoid arthritis - A five-year followup study, Arthritis and Rheumatism 48(6).
- Lard LR, van Gaalen FA, Schonkeren JJM, Pieterman EJ, Stoeken G, Vos K, Nelissen RGHH, Westendorp RGJ, Hoeben RC, Breedveld FC, Toes REM & Huizinga TWJ (2003), Association of the-2849 interleukin-10 promoter polymorphism with autoantibody production and joint destruction in rheumatoid arthritis, Arthritis and Rheumatism 48(7).
- Badrising UA, Maat-Schieman MLC, Ferrari MD, Zwinderman AH, Wessels JAM, Breedveld FC, van Doorn PA, van Engelen BGM, Hoogendijk JE, Howeler CJ, de Jager AE, Jennekens FGI, Koehler PJ, de Visser M, Viddeleer A, Verschuuren JJ & Wintzen AR (2002), Comparison of weakness progression in inclusion body myositis during treatment with methotrexate or placebo, Annals of Neurology 51(3).
- Emery P, Breedveld FC, Dougados M, Kalden JR, Schiff MH & Smolen JS (2002), Early referral recommendation for newly diagnosed rheumatoid arthritis: evidence based development of a clinical guide, Annals of the Rheumatic Diseases 61(4).
- Breedveld FC (2002), Leflunomide in treatment of rheumatoid arthritis - Reply, Lancet 359(9312).
- Kraan TCTV, van Gaalen FA, Alizadeh AA, Fero M, Huizinga TWJ, Pieterman E, Breedveld FC, Botstein D, Brown PO & Verweij CL (2002), Distinctive gene expression profiles in synovial tissue from rheumatoid arthritis patients by cDNA microarray analysis., Arthritis and Rheumatism 46(9): S266-S267.
- van der Heijde D, Simon L, Smolen J, Strand V, Sharp J, Boers M, Breedveld F, Weisman M, Weinblatt M, Rau R & Lipsky P (2002), How to report radiographic data in randomized clinical trials in rheumatoid arthritis: Guidelines from a roundtable discussion, Arthritis and Rheumatism 47(2).
- Reece RJ, Kraan MC, Radjenovic A, Veale DJ, O'Connor PJ, Ridgway JP, Gibbon WW, Breedveld FC, Tak PP & Emery P (2002), Comparative assessment of leflunomide and methotrexate for the treatment of rheumatoid arthritis, by dynamic enhanced magnetic resonance imaging, Arthritis and Rheumatism 46(2).
- Visser H, le Cessie S, Vos K, Breedveld FC & Hazes JMW (2002), How to diagnose rheumatoid arthritis early - A prediction model for persistent (erosive) arthritis, Arthritis and Rheumatism 46(2).
- Mason U, Aldrich J, Breedveld F, Davis CB, Elliott M, Jackson M, Jorgensen C, Keystone E, Levy R, Tesser J, Totoritis M, Truneh A, Weisman M, Wiesenhutter C, Yocum D & Zhu J (2002), CD4 coating, but not CD4 depletion, is a predictor of efficacy with primatized (TM) monoclonal anti-CD4 treatment of active rheumatoid arthritis, Journal of Rheumatology 29(2).
- Lard LR, Boers M, Verhoeven A, Vos K, Visser H, Hazes JMW, Zwinderman AH, Schreuder GMT, Breedveld FC, de Vries RRP, van der Linden S, Zanelli E & Huizinga TWJ (2002), Early and aggressive treatment of rheumatoid arthritis patients affects the association of HLA class II antigens with progression of joint damage, Arthritis and Rheumatism 46(4).
- Drossaers-Bakker KW, Zwinderman AH, van Zeben D, Breedveld FC & Hazes JMW (2002), Pregnancy and oral contraceptive use do not significantly influence outcome in long term rheumatoid arthritis, Annals of the Rheumatic Diseases 61(5).
- Huizinga TWJ, Machold KP, Breedveld FC, Lipsky PE & Smolen JS (2002), Criteria for early rheumatoid arthritis - From Bayes' law revisited to new thoughts on pathogenesis, Arthritis and Rheumatism 46(5).
- Visser H, Vos K, Zanelli E, Verduyn W, Schreuder GMT, Speyer I, Breedveld FC & Hazes JMW (2002), Sarcoid arthritis: clinical characteristics, diagnostic aspects, and risk factors, Annals of the Rheumatic Diseases 61(6).
- Verburg RJ, Toes REM, Fibbe WE, Breedveld FC & van Laar JM (2002), High dose chemotherapy and autologous hematopoietic stem cell transplantation for rheumatoid arthritis: A review, Human Immunology 63(8).
- Drossaers-Bakker KW, Zwinderman AH, Vlieland TPMV, Van Zeben D, Vos K, Breedveld FC & Hazes JMW (2002), Long-term outcome in rheumatoid arthritis: A simple algorithm of baseline parameters can predict radiographic damage, disability, and disease course at 12-year followup, Arthritis and Rheumatism 47(4).
- Landewe RBM, Breedveld FC & Dijkmans BAC (2002), Methotrexate treatment and mortality in rheumatoid arthritis, Lancet 360(9339).
- Pascual M, Mataran L, Jones G, Shing D, van der Slik AR, Giphart MJ, Schreuder GMT, de Vries RRP, Breedveld FC, Roovers E, Zanelli E & Martin J (2002), HLA haplotypes and susceptibility to rheumatoid arthritis - More than class II genes, Scandinavian Journal of Rheumatology 31(5).
- Tijhuis GJ, Zwinderman AH, Hazes JMW, Van den Hout WB, Breedveld FC & Vlieland TPMV (2002), A randomized comparison of care provided by a clinical nurse specialist, an inpatient team, and a day patient team in rheumatoid arthritis, Arthritis and Rheumatism 47(5).
- Choy EHS, Panayi GS, Emery P, Madden S, Breedveld FC, Kraan MC, Kalden JR, Rascu A, Brown JCC, Rapson N & Johnston JM (2002), Repeat-cycle study of high-dose intravenous 4162W94 anti-CD4 humanized monoclonal antibody in rheumatoid arthritis. A randomized placebo-controlled trial, Rheumatology 41(10).
- Tolboom TCA, Pieterman E, van der Laan WH, Toes REM, Huidekoper AL, Nelissen RGHH, Breedveld FC & Huizinga TWJ (2002), Invasive properties of fibroblast-like synoviocytes: correlation with growth characteristics and expression of MMP-1, MMP-3, and MMP-10, Annals of the Rheumatic Diseases 61(11).
- Furst DE, Breedveld FC, Kalden JR, Smolen JS, Antoni CE, Bijlsma JWJ, Burmester GR, Cronstein B, Keystone EC, Kavanaugh A & Klareskog L (2002), Updated consensus statement on biological agents for the treatment of rheumatoid arthritis and other rheumatic diseases (May 2002), Annals of the Rheumatic Diseases 61.
- van Esch WJE, Reparon-Schuijt CC, Hamstra HJ, van Kooten C, Logtenberg T, Breedveld FC & Verweij CL (2002), Polyreactivity of human IgG Fc-binding phage antibodies constructed from synovial fluid CD38+B cells of patients with rheumatoid arthritis, Journal of Autoimmunity 19(4).
- Breedveld F.C. & Brooks P. (red.) (2001), Bailliere's Best Practice & Research Clinical Rheumatology. Best Practice & Research Clinical Rheumatology. London: Bailliere Tindall, A Harcourt Health Sciences Company.
- Lard LR, Visser H, Speyer I, vander Horst-Bruinsma IE, Zwinderman AH, Breedveld FC & Hazes JMW (2001), Early versus delayed treatment in patients with recent-onset rheumatoid arthritis: Comparison of two cohorts who received different treatment strategies, American Journal of Medicine 111(6).
- Reparon-Schuijt CC, van Esch WJE, van Kooten C, Ezendam NPM, Levarht EWN, Breedveld FC & Verweij CL (2001), Presence of a population of CD20+,CD38-B lymphocytes with defective proliferative responsiveness in the synovial compartment of patients with rheumatoid arthritis, Arthritis and Rheumatism 44(9).
- van Ede AE, Laan RFJM, Rood MJ, Huizinga TWJ, van de Laar MAFJ, van Denderen CJ, Westgeest TAA, Romme TC, de Rooij DJRAM, Jacobs MJM, de Boo TM, van der Wilt GJ, Severens JL, Hartman M, Krabbe PFM, Dijkmans BAC, Breedveld FC & van de Putte LBA (2001), Effect of folic or folinic acid supplementation on the toxicity and efficacy of methotrexate in rheumatoid arthritis - A forty-eight-week, multicenter, randomized, double-blind, placebo-controlled study, Arthritis and Rheumatism 44(7).
- Vos K, Visser H, Schreuder GMT, de Vries RRP, Zwinderman AH, Breedveld FC, Hazes JMW & Zanelli EH (2001), Human leukocyte antigen-DQ and DR polymorphisms predict rheumatoid arthritis outcome better than DR alone, Human Immunology 62(11).
- Furst DE, Keystone EC, Breedveld FC, Kalden JR, Smolen JS, Antoni CE, Burmester GR, Crofford LJ & Kavanaugh A (2001), Updated consensus statement on tumour necrosis factor blocking agents for the treatment of rheumatoid arthritis and other rheumatic diseases (April 2001), Annals of the Rheumatic Diseases 60.
- Verburg RJ, Kruize AA, van den Hoogen FHJ, Fibbe WE, Petersen EJ, Preijers F, Sont JK, Barge RMY, Bijlsma JWJ, van de Putte LB, Breedveld FC & van Laar JM (2001), High-dose chemotherapy and autologous hematopoietic stem cell transplantation in patients with rheumatoid arthritis - Results of an open study to assess feasibility, safety, and efficacy, Arthritis and Rheumatism 44(4).
- van Laar JM, Verburg RJ, Fibbe WE & Breedveld FC (2001), Intensive immunosuppression and autologous stem cell transplantation for patients with severe rheumatoid arthritis: The Leiden experience, Journal of Rheumatology 28.
- Snijders A, Elferink DG, Geluk A, van der Zanden AL, Vos K, Schreuder GMT, Breedveld FC, de Vries RRP & Zanelli EH (2001), An HLA-DRB1-derived peptide associated with protection against rheumatoid arthritis is naturally processed by human APCs, Journal of Immunology 166(8).
- van der Laan W, Molenaar E, Ronday K, Verheijen J, Breedveld F, Greenwald R, Dijkmans B & TeKoppele J (2001), Lack of effect of doxycycline on disease activity and joint damage in patients with rheumatoid arthritis. A double blind, placebo controlled trial, Journal of Rheumatology 28(9).
- Emery P, Reginster JY, Appelboom T, Breedveld FC, Edelmann E, Kekow J, Malaise M, Mola EM, Montecucco C, Sanda M, Sany J, Scott DL, Serni U & Seydoux G (2001), WHO Collaborating Centre consensus meeting on anti-cytokine therapy in rheumatoid arthritis, Rheumatology 40(6).
- Huizinga TWJ & Breedveld FC (2001), What will treatment of autoimmune diseases entail in 2010?, Springer Seminars in Immunopathology 23(1-2).
- Goossens PH, Verburg RJ & Breedveld FC (2001), Remission of Behcet's syndrome with tumour necrosis factor alpha blocking therapy, Annals of the Rheumatic Diseases 60(6).
- Binks M, Passweg JR, Furst D, McSweeney P, Sullivan K, Besenthal C, Finke J, Peter HH, van Laar J, Breedveld FC, Fibbe VE, Farge D, Gluckman E, Locatelli F, Martini A, van den Hoogen F, van de Putte L, Schattenberg AVN, Arnold R, Bacon PA, Emery P, Espigado I, Hertenstein B, Hiepe F, Kashyap A, Kotter I, Marmont A, Martinez A, Pascual MJ, Gratwohl A, Prentice HG, Black C & Tyndall A (2001), Phase I/II trial of autologous stem cell transplantation in systemic sclerosis: procedure related mortality and impact on skin disease, Annals of the Rheumatic Diseases 60(6).
- Van Esch WJE, Reparon-Schuijt CC, Levarht EWN, Van Kooten C, Breedveld FC & Verweij CL (2001), Differential requirements for induction of total immunoglobulin and physiological rheumatoid factor production by human peripheral blood B cells, Clinical and Experimental Immunology 123(3).
- Goekoop YPM, Allaart CFR, Breedveld FC & Dijkmans BAC (2001), Combination therapy in rheumatoid arthritis, Current Opinion in Rheumatology 13(3).
- Vos K, van der Horst-Bruinsma IE, Hazes JMW, Breedveld FC, le Cessie S, Schreuder GMT, de Vries RRP & Zanelli E (2001), Evidence for a protective role of the human leukocyte antigen class II region in early rheumatoid arthritis, Rheumatology 40(2).
- Reijnierse M, Dijkmans BAC, Hansen B, Pope TL, Kroon HM, Holscher HC, Breedveld FC & Bloem JL (2001), Neurologic dysfunction in patients with rheumatoid arthritis of the cervical spine. Predictive value of clinical, radiographic and MR imaging parameters, European Radiology 11(3).
- Rood MJ, Haverman JF, van Duinen SG, Breedveld FC, Verschuuren JJGM & Huizinga TWJ (2001), CNS involvement in systemic lupus erythematosus: a case with remarkable histopathological findings, Annals of the Rheumatic Diseases 60(3).
- Kraan MC, Smith MD, Weedon H, Ahern MJ, Breedveld FC & Tak PP (2001), Measurement of cytokine and adhesion molecule expression in synovial tissue by digital image analysis, Annals of the Rheumatic Diseases 60(3).
- Zanelli E, Jones G, Pascual M, Eerligh P, van der Slik AR, Zwinderman AH, Verduyn W, Schreuder GMT, Roovers E, Breedveld FC, de Vries RRP, Martin J & Giphart MJ (2001), The telomeric part of the HLA region predisposes to rheumatoid arthritis independently of the class II loci, Human Immunology 62(1).
- Ronday, H.K.; Laan, W.H. van der; Tak, P.P.; Roos, J.A.D.M. de; Bank, R.A.; TeKoppele, J.M.; Froelich, C.J.; Hack, C.E.; Hogendoorn, P.C.W.; Breedveld, F.C. & Verheijen, J.H. (2001), Human granzyme B mediates cartilage proteoglycan degradation and is expressed at the invasive front of the synovium in rheumatoid arthritis, Rheumatology 40(1).
- Goossens PH, Vogels R, Pieterman E, Havenga MJE, Bout A, Breedveld FC, Valerio D & Huizinga TWJ (2001), The influence of synovial fluid on adenovirus-mediated gene transfer to the synovial tissue, Arthritis and Rheumatism 44(1).
- Reparon-Schuijt CC, van Esch WJE, van Kooten C, Schellekens GA, de Jong BAW, van Venrooij WJ, Breedveld FC & Verweij CL (2001), Secretion of anti-citrulline-containing peptide antibody by B lymphocytes in rheumatoid arthritis, Arthritis and Rheumatism 44(1).
- Visser H, Speyer I, Ozcan B, Breedveld FC, van Ogtrop ML & Hazes JMW (2000), The diagnostic value of streptococcal serology in early arthritis: a prospective cohort study, Rheumatology 39(12).
- Vos K, Miltenburg AMM, van Meijgaarden KE, van den Heuvel M, Elferink DG, van Galen PJM, van Hogezand RA, van Vliet-Daskalopoulou E, Ottenhoff THM, Breedveld FC, Boots AMH & de Vries RRP (2000), Cellular immune response to human cartilage glycoprotein-39 (HC gp-39)-derived peptides in rheumatoid arthritis and other inflammatory conditions, Rheumatology 39(12).
- Hulshof MM, Bavinck JNB, Bergman W, Masclee AAM, Heickendorff L, Breedveld FC & Dijkmans BAC (2000), Double-blind, placebo-controlled study of oral calcitriol for the treatment of localized and systemic scleroderma, Journal of The American Academy of Dermatology 43(6).
- Huizinga TWJ, Keijsers V, Yanni G, Hall M, Ramage W, Lanchbury J, Pitzalis C, Drossaers-Bakker WK, Westendorp RGJ, Breedveld FC, Panayi G & Verweij CL (2000), Are differences in interleukin 10 production associated with joint damage?, Rheumatology 39(11).
- Lipsky PE, van der Heijde DMFM, St Clair EW, Furst DE, Breedveld FC, Kalden JR, Smolen JS, Weisman M, Emery P, Feldmann M, Harriman GR & Maini RN (2000), Infliximab and methotrexate in the treatment of rheumatoid arthritis, New England Journal of Medicine 343(22).
- Furst DE, Breedveld FC, Burmester GR, Crofford JJ, Emery P, Feldmann M, Kalden JR, Kavanaugh AF, Keystone EC, Klareskog LG, Lipsky PE, Maini RN, Russell AS, Scott DL, Smolen JS, Van de Putte LBA, Visher TL & Weisman MH (2000), Updated consensus statement on tumour necrosis factor blocking agents for the treatment of rheumatoid arthritis (May 2000), Annals of the Rheumatic Diseases 59.
- Breedveld FC, Kalden JR & Smolen JS (2000), Advances in targeted therapies II, Annals of the Rheumatic Diseases 59.
- Badrising UA, Maat-Schieman M, van Duinen SG, Breedveld F, van Doorn P, van Engelen B, van den Hoogen F, Hoogendijk J, Howeler C, de Jager A, Jennekens F, Koehler P, van der Leeuw H, de Visser M, Verschuuren JJ & Wintzen AR (2000), Epidemiology of inclusion body myositis in the Netherlands: A nationwide study, Neurology 55(9).
- Zanelli E, Breedveld FC & de Vries RRP (2000), HLA association with autoimmune disease: a failure to protect?, Rheumatology 39(10).
- Goossens PH, Schouten GJ, Heemskerk B, 't Hart BA, Bout A, Kluin PM, Breedveld FC, Valerio D & Huizinga TWJ (2000), The effect of promoter strength in adenoviral vectors in hyperplastic synovium, Clinical and Experimental Rheumatology 18(5).
- Drossaers-Bakker KW, Kroon HM, Zwinderman AH, Breedveld FC & Hazes JMW (2000), Radiographic damage of large joints in long-term rheumatoid arthritis and its relation to function, Rheumatology 39(9).
- van den Ende CHM, Breedveld FC, le Cessie S, Dijkmans BAC, de Mug AW & Hazes JMW (2000), Effect of intensive exercise on patients with active rheumatoid arthritis: a randomised clinical trial.
- Verschueren PC, Voskuyl AE, Smeets TJ, Zwinderman KH, Breedveld FC & Tak PP (2000), Increased cellularity and expression of adhesion molecules in muscle biopsy specimens from patients with rheumatoid arthritis with clinical suspicion of vasculitis, but negative routine histology.
- Emery P, Breedveld FC, Lemmel EM, Kaltwasser JP, Dawes PT, Gomor B, Van den Bosch F, Nordstrom D, Bjorneboe O, Dahl R, Horslev-Petersen K, de la Serna AR, Molloy M, Tikly M, Oed C, Rosenburg R & Loew-Friedrich I (2000), A comparison of the efficacy and safety of leflunomide and methotrexate for the treatment of rheumatoid arthritis.
- Kraan MC, De Koster BM, Elferink JGR, Post WJ, Breedveld FC & Tak PP (2000), Inhibition of neutrophil migration soon after initiation of treatment with leflunomide or methotrexate in patients with rheumatoid arthritis - Findings in a prospective, randomized, double-blind clinical trial in fifteen patients.
- Drossaers-Bakker KW, Amesz E, Zwinderman AH & Breedveld FC (2000), Comparison of three radiologic scoring systems for the long-term assessment of rheumatoid arthritis - Findings of an ongoing prospective inception cohort study of 132 women followed up for a median of twelve years.
- Vos K, Steenbakkers P, Miltenburg AMM, Bos E, van den Heuvel MW, van Hogezand RA, de Vries RRP, Breedveld FC & Boots AMH (2000), Raised human cartilage glycoprotein-39 plasma levels in patients with rheumatoid arthritis and other inflammatory conditions.
- Smolen JS, Breedveld FC, Burmester GR, Combe B, Emery P, Kalden JR, Klareskog L, Maini RN, Numo R, van de Putte LBA, van Riel PLCM & Rodriguez-Valverde V (2000), Consensus statement on the initiation and continuation of tumour necrosis factor blocking therapies in rheumatoid arthritis.
- Landewe RBM, van den Borne BEEM, Breedveld FC & Dijkmans BAC (2000), Methotrexate effects in patients with rheumatoid arthritis with cardiovascular comorbidity.
- Reparon-Schuijt CC, van Esch WJE, van Kooten C, Rozier BCD, Levarht EWN, Breedveld FC & Verweij CL (2000), Regulation of synovial B cell survival in rheumatoid arthritis by vascular cell adhesion molecule 1 (CD106) expressed on fibroblast-like synoviocytes.
- Zanelli E, Vos K, Breedveld F, de Vries R & David C (2000), Role of HLA-DQ in rheumatoid arthritis susceptibility: comment on the article by Be Vries ct al.
- Reijnierse M, Breedveld FC, Kroon HM, Hansen B, Pope TL & Bloem JL (2000), Are magnetic resonance flexion views useful in evaluating the cervical spine of patients with rheumatoid arthritis?
- Breedveld FC (2000), Therapeutic monoclonal antibodies.
- Rood MJ, Verschuuren JJGM, van Duinen SG, Maat-Schieman ML, Hegeman-Kleinn IM, van Buchem MA, Breedveld FC & Huizinga TWJ (2000), CNS involvement in primary Sjogren's syndrome: a case with a clue for the pathogenesis.
- Schellekens GA, Visser H, de Jong BAW, Van den Hoogen FHJ, Hazes JMW, Breedveld FC & van Venrooij WJ (2000), The diagnostic properties of rheumatoid arthritis antibodies recognizing a cyclic citrullinated peptide.
- Rood MJ, Van Krugten MV, Zanelli E, Van der Linden MW, Keijsers V, Schreuder GMT, Verduyn W, Westendorp RGJ, De Vries RRP, Breedveld FC, Verweij CL & Huizinga TWJ (2000), TNF-308A and HLA-DR3 alleles contribute independently to susceptibility to systemic lupus erythematosus.
- van Krugten MV, Huizinga TWJ, Kaijzel EL, Zanelli E, Drossaers-Bakker KW, van de Linde P, Hazes JMW, Zwinderman AH, Breedveld FC & Verweij CL (1999), Association of the TNF+489 polymorphism with susceptibility and radiographic damage in rheumatoid arthritis.
- Meulenbelt I, Bijkerk C, De Wildt SCM, Miedema HS, Breedveld FC, Pols HAP, Hofman A, Van Duijn CM & Slagboom PE (1999), Haplotype analysis of three polymorphisms of the COL2A1 gene and associations with generalised radiological osteoarthritis.
- Breedveld FC (1999), Investigational treatments in rheumatoid arthritis.
- 3 lezingen per jaar
- voorzitter Raad van Toezicht
- voorzitter Raad van Toezicht