Amina Teunisse
- Naam
- Ing. A.F.A.S. Teunisse
- Telefoon
- +31 71 526 9111
- a.f.a.s.teunisse@lumc.nl
- Faculteit Geneeskunde
- Divisie 4
- Cel en Chemische biologie
- Mamunur Rashid, Clare Pacini, Droop Alastair, Holly Robertson, Francesco Iorio & David J. Adams (2020), Analysis of CRISPR‐Cas9 screens identifies genetic dependencies in melanoma, Pigment Cell and Melanoma Research.
- Christodoulou, E.; Doorn, R. van; Visser, M.; Teunisse, A.; Versluis, M.; Velden, P. van der; Hayward, N.K.; Jochemsen, A. & Gruis, N. (2019), NEK11 as a candidate high-penetrance melanoma susceptibility gene, Journal of Medical Genetics 56(11).
- Ent W. van der, Jochemsen A.G., Teunisse A.F., Krens S.G., Szuhai K., Spaink H.P., Hogendoorn P.C. & Snaar-Jagalska B.E. (2014), Ewing sarcoma inhibition by disruption of EWSR1-FLI1 transcriptional activity and reactivation of p53, Journal of Pathology 223(4): 415-424.
- Lange, J. de; Ly, L.V.; Lodder, K.; Verlaan-de Vries, M.; Teunisse, A.F.A.S.; Jager, M.J. & Jochemsen, A.G. (2012), Synergistic growth inhibition based on small-molecule p53 activation as treatment for intraocular melanoma, Oncogene 31(9): 1105-1116.
- Spinnler, C.; Hedstrom, E.; Li, H.; Lange, J. de; Nikulenkov, F.; Teunisse, A.F.A.S.; Verlaan-de Vries, M.; Grinkevich, V.; Jochemsen, A.G. & Selivanova, G. (2011), Abrogation of Wip1 expression by RITA-activated p53 potentiates apoptosis induction via activation of ATM and inhibition of HdmX, Cell Death and Differentiation 18(11): 1736-1745.
- Lenos, K.; Lange, J. de; Teunisse, A.F.A.S.; Lodder, K.; Verlaan-de Vries, M.; Wiercinska, E.; Burg, M.J.M. van der; Szuhai, K. & Jochemsen, A.G. (2011), Oncogenic functions of hMDMX in in vitro transformation of primary human fibroblasts and embryonic retinoblasts, Molecular Cancer 10: -.
- Lange, J. de; Ly, L.V.; Lodder, K.; Verlaan-de Vries, M.; Teunisse, A.F.A.S.; Jager, M.J. & Jochemsen, A.G. (2011), Synergistic growth inhibition based on small-molecule p53 activation as treatment for intraocular melanoma., Oncogene.
- Phillips, A.; Teunisse, A.; Lam, S.; Lodder, K.; Darley, M.; Emaduddin, M.; Wolf, A.; Richter, J.; Lange, J. de; Verlaan-de Vries, M.; Lenos, K.; Bohnke, A.; Bartel, F.; Blaydes, J.P. & Jochemsen, A.G. (2010), HDMX-L Is Expressed from a Functional p53-responsive Promoter in the First Intron of the HDMX Gene and Participates in an Autoregulatory Feedback Loop to Control p53 Activity, Journal of Biological Chemistry 285(38): 29111-29127.
- Hollestelle, A.; Nagel, J.H.A.; Smid, M.; Lam, S.; Elstrodt, F.; Wasielewski, M.; Ng, S.S.; French, P.J.; Peeters, J.K.; Rozendaal, M.J.; Riaz, M.; Koopman, D.G.; Hagen, T.L.M. ten; Leeuw, B.H.C.G.M. de; Zwarthoff, E.C.; Teunisse, A.; Spek, P.J. van der; Klijn, J.G.M.; Dinjens, W.N.M.; Ethier, S.P.; Clevers, H.; Jochemsen, A.G.; Bakker, M.A. den; Foekens, J.A.; Martens, J.W.M. & Schutte, M. (2010), Distinct gene mutation profiles among luminal-type and basal-type breast cancer cell lines, Breast Cancer Research and Treatment 121(1): 53-64.
- Lam, S.; Lodder, K.; Teunisse, A.F.A.S.; Rabelink, M.J.W.E.; Schutte, M. & Jochemsen, A.G. (2010), Role of Mdm4 in drug sensitivity of breast cancer cells, Oncogene 29(16): 2415-2426.
- Boesten L.S., Zadelaar A.S.,Nieuwkoop A. van, Hu L., Teunisse A.F.A.S., Jochemsen A.G., Evers B., Water B. van de, Gijbels M.J., Vlijmen B.J. van & Havekes L.M. Winther M.P. de (2009), Macrophage p53 controls macrophage death in atherosclerotic lesions of apolipoprotein E deficient mice, Atherosclerosis 207(2): 399-404.
- Boesten LSM, Zadelaar ASM, van Nieuwkoop A, Hu LH, Teunisse AFAS, Jochemsen AG, Evers B, van de Water B, Gijbels MJJ & van Vlijmen BJM (2009), Macrophage p53 controls macrophage death in atherosclerotic lesions of apolipoprotein E deficient mice, Atherosclerosis 207(2): 399-404.
- Laurie NA, Donovan SL, Shih CS, Zhang JK, Mills N, Fuller C, Teunisse A, Lam S, Ramos Y, Mohan A, Johnson D, Wilson M, Rodriguez-Galindo C, Quarto M, Francoz S, Mendrysa SM, Guy RK, Marine JC, Jochemsen AG & Dyer MA (2006), Inactivation of the p53 pathway in retinoblastoma, Nature 444(7115).
- Pereg Y, Lam S, Teunisse A, Biton S, Meulmeester E, Mittelman L, Buscemi G, Okamoto K, Taya Y, Shiloh Y & Jochemsen AG (2006), Differential roles of ATM- and Chk2-mediated phosphorylations of Hdmx in response to DNA damage, Molecular and Cellular Biology 26(18).
- Okamoto K, Kashima K, Pereg Y, Ishida M, Yamazaki S, Nota A, Teunisse A, Migliorini D, Kitabayashi I, Marine JC, Prives C, Shiloh Y, Jochemsen AG & Taya Y (2005), DNA damage-induced phosphorylation of MdmX at Serine 367 activates p53 by targeting MdmX for Mdm2-dependent degradation, Molecular and Cellular Biology 25(21).
- Meulmeester E, Maurice MM, Boutell C, Teunisse AFAS, Ovaa H, Abraham TE, Dirks RW & Jochemsen AG (2005), Loss of HAUSP-mediated deubiquitination contributes to DNA damage-induced destabilization of Hdmx and Hdm2, Molecular Cell 18(5).
- Pereg Y, Shkedy D, de Graaf P, Meulmeester E, Edelson-Averbukh M, Salek M, Biton S, Teunisse AFAS, Lehmann WD, Jochemsen AG & Shiloh Y (2005), Phosphorylation of Hdmx mediates its Hdm2- and ATM-dependent degradation in response to DNA damage, Proceedings of the National Academy of Sciences 102(14).