Universiteit Leiden

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Sophie Wintermans

PhD candidate

Name
Ir. S.E.L. Wintermans
Telephone
+31 71 527 2727
E-mail
s.e.l.wintermans@lic.leidenuniv.nl

Sophie Wintermans obtained her BSc and MSc in Molecular Life Sciences from Wageningen University & Research (Wageningen, the Netherlands). There, she specialized in both organic chemistry and biochemistry, with a focus on early drug development. During an internship with Symeres (Nijmegen, the Netherlands), she synthesized cyclin dependent kinase inhibitors for developing new anti-cancer drugs. During her MSc thesis with Dr. Bauke Albada, she worked with DNA catalysts called nucleoapzymes to selectively modify tyrosine residues in an enzyme-like fashion, which can be used as a tool for e.g., bioconjugation of drugs to antibodies. She then joined the Medical Biochemistry lab (Leiden University, the Netherlands) as a PhD candidate under the supervision of Dr. Marta Artola and Dr. René Olsthoorn to develop new small-molecule drugs targeting RNA pseudoknots. For this, she developed a novel high throughput assay to screen for potential RNA-binding molecules, which can now be applied to different RNA structures in hopes of finding new antimicrobial compounds.

PhD candidate

  • Science
  • Leiden Institute of Chemistry
  • LIC/Chemical Biology
  • LIC/CB/Medical Biochemistry

Work address

Gorlaeus Building
Einsteinweg 55
2333 CC Leiden

Contact

Publications

No relevant ancillary activities

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