Linda Aulin
Assistant professor
- Name
- Dr. L.B.S. Aulin
- Telephone
- 071 5272727
- l.b.s.aulin@lacdr.leidenuniv.nl
- ORCID iD
- 0000-0003-4840-5704
Assistant professor
- LACDR
- Divisie Systems Pharmacology and Pharmacy
- Tandar S.T., Clercq A. de, Aulin L.B.S., Biesen W. van, Delanghe S, Vanommeslaeghe F., Paepe P. de, Hasselt J.G.C. van Cock P.A. de & Eloot S. (2026), Model-based optimisation for teicoplanin dosing in patients undergoing maintenance haemodialysis, Clinical Microbiology and Infection 32(3): 466-473.
- Otto M.E., Jacobs G.E., Mechelen J.C. van, Borghans L.G.J.M., Hasselt J.G.C. van & Aulin L.B.S. (2026), Pharmacokinetics and pharmacodynamics of intravenous and oral (S)‐ketamine: Investigating metabolite contribution to subjective effects: investigating metabolite contribution to subjective effects, British Journal of Clinical Pharmacology 92(7): 2260-2271.
- Tandar S.T., Zwep L.B, Woudt S.H.S., Schoffelen A.F., Smits W.K., Aulin L.B.S., Liakopoulos A., Hasselt J.G.C., Cohen S.J.W.T., Melles D.C., Dijk K. van, Alzubaidy A., Scholing M., Kuil S.D., Blaauw G.J., Bijllaardt W., Kraan E.M., Haeseker M.B., Da Silva J.M., Jong E. de, Maraha B., Griethuysen A.J. van, Wintermans B.B., Trijp M.J.C.A. van, Muller A.E., Wong M., Ott A., Bathoorn E., Lokate M., Sinnige J., Melles D.C., Bank L. & Sebens F.W. Renders N H Dorigo-Zetsma J W Bakker L J Ang W Waar K van der Beek M T Leversteijn-van Hall M A van Mens S P Schaftenaar E Nabuurs-Franssen M H Maat I Sturm P D J Diederen B M W Bode L G M Ong D S Y van Rijn M Dinant S Reijer M den van Dam D W de Brauwer E I G B Bentvelsen R G Stohr J J J M Vlek A L M de Graaf M Troelstra A Gast K B van Meer M P A de Vries J Debast S B Altorf van der Kuil W Bierman S M de Greeff S C Groenendijk S R Hertroys R Kruithof L Nauta I M Notermans D W Polman J van den Reek W J Schoffelen A F Velthuis F Wielders C C H de Wit B J Zoetigheid R E (2026), Clinical prevalence of collateral sensitivity: a systematic exploration of multicentre antimicrobial surveillance data, The Lancet. Microbe 7(4): 101274 (101274).
- Alarcon Rios A.C., Zwep L.B., Vriesendorp B., Knibbe C.A.J., Ciofu O., Liakopoulos A., Aulin L.B.S., Rozen D.E. & Hasselt J.G.C. van (2025), Colistin resistance dynamics in Pseudomonas aeruginosa under biofilm and planktonic growth, Antimicrobial Agents and Chemotherapy 69(10): e00421-25.
- Tandar S.T., Aulin L.B.S., Leemkuil E. M.J., Liakopoulos A. & Hasselt J.G.C. van (2024), Semi-mechanistic modeling of resistance development to β-lactam and β-lactamase-inhibitor combinations, Journal of Pharmacokinetics and Pharmacodynamics 51: 199-211.
- Liu F., Aulin L.B.S. & Manson M.L. Krekels E.H.J. Hasselt J.G.C. van (2023), Unraveling the effects of acute inflammation on pharmacokinetics: a model-based analysis focusing on renal glomerular filtration rate and cytochrome P450 3A4-mediated metabolism, European Journal of Drug Metabolism and Pharmacokinetics 48: 623–631.
- Healy K., Aulin L.B.S., Freij U., Ellerstad M., Brückle L., Hillmering H., Svae T.E., Broliden K. & Gustafsson R. (2023), Prevalence of parvovirus B19 viremia among German blood donations and the relationship to ABO and rhesus blood group antigens, The Journal of Infectious Diseases 227(10): 1214-1218.
- Liakopoulos A., Aulin L.B.S., Buffoni M., Fragkiskou E., Hasselt J.G.C. van & Rozen D.E. (2022), Allele-specific collateral and fitness effects determine the dynamics of fluoroquinolone resistance evolution, Proceedings of the National Academy of Sciences 119(18): e2121768119.
- Aulin L.B.S., Kleijburg A., Moerland M. & Hasselt J.G.C. van (2022), Characterizing the kinetics of presepsin and associated inflammatory biomarkers in human endotoxemia, Inflammation Research 71(9): 999-1001.
- Healy K., Freij U., Ellerstad M., Aulin L.B.S., Brückle L., Hillmering H., Chen M.S. & Gustafsson R. (2022), Evaluating the prevalence of Hepatitis E virus infection in a large cohort of European blood donors, 2015-2018, Journal of Viral Hepatitis 29(9): 835-839.
- Liu F., Aulin L.B.S., Guo T., Krekels E.H.J., Moerland M., Graaf P.H. van der & Hasselt J.G.C. van (2022), Modelling inflammatory biomarker dynamics in a human lipopolysaccharide (LPS) challenge study using delay differential equations, British Journal of Clinical Pharmacology 88(12): 5420-5427.
- Aulin L.B.S., Tandar S.T., Zijp T. van, Ballegooie E. van, Graaf P.H. van der, Saleh M.A.A.E.W., Välitalo P. & Hasselt J.G.C. van (2022), Physiologically based modelling framework for prediction of pulmonary pharmacokinetics of antimicrobial target site concentrations, Clinical Pharmacokinetics 61: 1735-1748.
- Aulin L.B.S. (14 December 2022), Quantitative pharmacology of antimicrobials (Dissertatie. Leiden Academic Centre for Drug Research (LADCR), Faculty of Science, Leiden University). Supervisor(s) and Co-supervisor(s): Graaf P.H. van der, Hasselt J.G.C. van.
- Aulin L.B.S., De Paepe. P., Dhont E., Jaeger A. de, Vande Walle J., Vandenberghe W., McWhinney B.C., Ungerer J.P.J., Hasselt J.G.C. van & Cock P.A.J.G. de (2021), Population pharmacokinetics of unbound and total teicoplanin in critically ill pediatric patients, Clinical Pharmacokinetics 60: 353-363.
- Aulin L.B.S., Koumans C.I.M., Haakman Y., Os W. van, Kraakman M.E.M., Gooskens J., Smits W.K., Liakopoulos A. & Hasselt J.G.C. van (2021), Distinct evolution of colistin resistance associated with experimental resistance evolution models in Klebsiella pneumoniae, Journal of Antimicrobial Chemotherapy 76(2): 533-535.
- Aulin L.B.S., Lange D.W. de, Saleh M.A.A., Graaf P.H. van der, Völler S. & Hasselt J.G.C. (2021), Biomarker-guided individualization of antibiotic therapy, Clinical Pharmacology & Therapeutics 110(2): 346-360.
- Aulin L.B.S., Liakopoulos A., Graaf P.H. van der, Rozen D.E. & Hasselt J.G.C. (2021), Design principles of collateral sensitivity-based dosing strategies, Nature Communications 12: 5691.
- Aulin L.B.S., Valitalo P.A., Rizk M.L., Visser S.A.G., Rao G., Graaf P.H. van der & Hasselt J.G.C. van (2018), Validation of a Model Predicting Anti-infective Lung Penetration in the Epithelial Lining Fluid of Humans, Pharmaceutical Research 35(2): 26.