Universiteit Leiden

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Christian Tudorache

Assistant professor

Name
Dr. C. Tudorache
Telephone
+31 71 527 4759
E-mail
c.tudorache@biology.leidenuniv.nl

My research focuses on physiological mechanisms and interactions underlying stress and behavioural responses to stressors. Since the study of stress is multi-disciplinary and integrative, my research combines physiology, behaviour, and molecular biology, but also includes morphology, biomechanics and toxicology.

More information about Christian Tudorache

Brief Biography

  • 2014- present Postdoctoral fellow (IBL), Leiden University, The Netherlands. Collaborators: Dr. Marcel Schaaf, Dr. Hans Slabbekoorn
  • 2010-2014 Postdoctoral fellow (VENI), Leiden University, The Netherlands. Supervisors: Dr. Guido van den Thillart, Prof. Dr. Herman Spaink
  • 2009-2010 Consultant, Ecological Engineering Antea Group, Rotterdam, The Netherlands. 
  • 2008-2009 Postdoctoral fellow (Hydro Manitoba), University of New Brunswick, Fredericton, Canada. Supervisor: Prof. Dr. Tillmann Benfey
  • 2004-2008 PhD student, Antwerp University, Belgium. Promotor: Prof. Dr. Ronny Blust, Co-promotor: Prof. Dr. Gudrun de Boeck

Research

My research focuses on physiological mechanisms and interactions underlying stress and behavioural responses to stressors. Since the study of stress is multi-disciplinary and integrative, my research combines physiology, behaviour, and molecular biology, but also includes morphology, biomechanics and toxicology.

Stress (eco)physiology and toxicology

During long-term swimming, fish are exposed to a variety of environmental stressors. In order to study the energetics of active swimming, I develop new, environmentally relevant approaches, combining classical and novel research methodologies such as respirometry, fitness tests, volitional swimming behaviour and kinematics. In this light, I use (neuro)behavioural and biomechanical methods to split aerobically and anaerobically powered swimming modes as affected by ammonia toxicity, and define chemical and biological, not only physical, obstructions for free migration in the filed.

Stress coping styles

Recently, variations in stress coping styles became a widespread research topic, relevant for a variety of fields. Although not always examined together, molecular biology, physiology and behaviour are almost always interwoven and interact with each other. The application of personalities in medical issues, including personalised medicine, susceptibility to and heritability of various diseases, is a promising new field of research. Zebrafish are an upcoming model in this new field of stress research.

I use swimming kinematics to detect and characterize the behavioural stress response during volitional activity in zebrafish larvae and a combination of molecular and behavioural techniques to elicit the temporal aspects of the physiological stress response in adult zebrafish. Classic and newly developed methods for my research on swimming physiology cover: respirometry, locomotion kinematics and behavioural methods. Answering questions related to epigenetic and adaptation mechanisms, this research branch finds applications in medical biology, animal welfare and environmental health issues, including personality disorders, toxicology and global change.

Assistant professor

  • Wiskunde en Natuurwetenschappen
  • Instituut Biologie Leiden
  • IBL Animal Sciences & Health

Work address

Sylvius
Sylviusweg 72
2333 BE Leiden
Room number 6.514B

Contact

Publications

  • Geen relevante nevenwerkzaamheden

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