Universiteit Leiden

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Bart Roep

Professor Diabetology, in particular the immunopathology of type 1 diabetes mellitus

Name
Prof.dr. B.O. Roep
Telephone
+31 71 526 3869
E-mail
b.o.roep@lumc.nl

Dr. Bart O. Roep is Professor of Diabetology, Immunopathology & Intervention and Director of the National Diabetes Center of Excellence at the Leiden University Medical Center in The Netherlands and Visiting Professor of the Danish Diabetes Academy. He is also Founding Chair and Professor of Medicine of the Department of Diabetes Immunology, and holds the Chan Soon-Shiong Shapiro Distinguished Chair in Diabetes at the Diabetes & Metabolism Research Institute at the Beckman Research Institute of the City of Hope in Los Angeles.

More information about Bart Roep

Dr. Bart O. Roep is Professor of Diabetology, Immunopathology & Intervention and Director of the National Diabetes Center of Excellence at the Leiden University Medical Center in The Netherlands and Visiting Professor of the Danish Diabetes Academy. He is also Founding Chair and Professor of Medicine of the Department of Diabetes Immunology, and holds the Chan Soon-Shiong Shapiro Distinguished Chair in Diabetes at the Diabetes & Metabolism Research Institute at the Beckman Research Institute of the City of Hope in Los Angeles.

Type 1 diabetes

Dr. Roep’s mission is to understand the cause of type 1 diabetes in humans, and translate this knowledge into innovative strategies for immune intervention therapy aiming at a cure for type 1 diabetes.

Academic career

After studying medical sciences at the University of Amsterdam, he obtained his PhD in medicine at the Leiden University Medical Center. Dr. Roep was postdoc at the University of California in San Francisco in 1990 and 1991, after which he continued his career in the LUMC. In 2016, he joined the Diabetes & Metabolism Research Institute at the Beckman Diabetes Institute and National Medical Center at the City of Hope in Los Angeles to lead the Wanek Family Project to cure type 1 diabetes.

Dr. Roep discovered the role of T cells in diabetes and focused on defining human cellular immune responses, autoantigen identification, and islet transplantation and the design, execution and immunological monitoring of immune intervention strategies in clinical type 1 diabetes and beta-cell replacement therapies, including pioneering trials on tissue-specific tolerance induction, clinical islet transplantation, and gene and stem cell therapy. He is founder and director of the national platform for clinical immune intervention therapy in The Netherlands and published more than 350 original articles on his discoveries. He received many prestigious awards, including the Minkowski Prize, the VICI award and a Fellowship of the Royal Dutch Academy of Arts and Sciences.

Prizes and honourable appointments

  • Eli Lilly Diabetes Award 1990-1991
  • Royal Academy of Arts and Sciences Fellow 1993
  • Marie Parijs Prize for Innovative Clinical Research 1999
  • Minkowski Prize 2002
  • Mary Jane Kugel Research Award, JDRF, New York 2007
  • Vici Award ZonMW 2007
  • Presidential Lecture, EASD-AIDPIT Society, Igles-Innsbruck, 2010, 2013, 2014
  • Dutch Diabetes Patient Society Award 2010
  • Corona-Gallina Prize 2011
  • JDRF Netherlands Award for T1D Scientific Excellence, 2013
  • Gerold & Kayla Grodsky Award 2014
  • Elected Member of the Danish Diabetes Academy 2015
  • Lifetime Achievement Award from the JDRF Network for Pancreatic Organ Donors 2016
  • Poll Visiting Scholar at the University of Washington’s Diabetes Research Center, 2017
  • Endowment Chan Soon-Shiong Shapiro Distinguished Chair in Diabetes, 2017

More information

https://mediator.zonmw.nl/mediator-26-november-2017/zicht-op-vaccin-tegen-diabetes-type-1/
https://www.diabetes.co.uk/in-depth/interview-dr-bart-roep-man-wants-cure-type-1-diabetes-within-six-years/

Professor Diabetology, in particular the immunopathology of type 1 diabetes mellitus

  • Faculteit Geneeskunde
  • Divisie 4
  • Immunohematologie en Bloedtransfusie

Work address

LUMC Main Building
Albinusdreef 2
2333 ZA Leiden
Room number E3-Q

Contact

Publications

  • Beckman Research Institute Afdelingshoofd Department Diabetes Immunology
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