Dissertation
The impact of non-genetic factors on drug metabolism: towards better phenotype predictions
This thesis investigates how non-genetic factors, such as inflammation and concomitant medication, impact hepatic drug metabolism and subsequent drug metabolizing phenotype predictions.
- Author
- L.M. de Jong
- Date
- 05 June 2025
- Links
- Thesis in Leiden Repository
This work is grounded in the hypothesis that these factors significantly affect drug metabolism and, therefore, should be incorporated into pharmacogenetic-based phenotype predictions.