Bioorthogonal deprotection strategy to study T-cell activation and cross- presentation
Cytotoxic T-cells (CTLs) are involved in the clearance of viruses and killing of tumor cells.
- Lahav-van der Gracht, A.M.F.
- 13 October 2020
- Thesis in Leiden Repository
Cytotoxic T-cells (CTLs) are involved in the clearance of viruses and killing of tumor cells. The capacity of these killer cells to clear viruses and kill tumor cells can be harbored by the creation of vaccines. Improving understanding of T-cell activation and the possibility to understand, influence or even have control over this process might lead to better anti-cancer vaccines. Chemical tools can be a good addition to fill in the gaps of knowledge about T-cell activation.